2,865 results match your criteria Lacrimal Gland Tumors


Paediatric ocular adnexal lymphoma: a population-based analysis.

BMJ Open Ophthalmol 2020 21;5(1):e000483. Epub 2020 Jun 21.

Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA.

Objective: To investigate the incidence, clinicopathological characteristics and survival of ocular adnexal lymphoma (OAL) in the paediatric population.

Methods And Analysis: In this retrospective case series, the Surveillance, Epidemiology and End Results database was accessed to identify individuals with OAL ≤18 years of age, diagnosed between 1973 and 2015. OAL located in the eyelid, conjunctiva, lacrimal apparatus and orbit were included. Read More

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http://dx.doi.org/10.1136/bmjophth-2020-000483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312335PMC

Reirradiation for Recurrent Scalp Angiosarcoma: Dosimetric Advantage of PBT over VMAT and EBT.

Int J Part Ther 2020 16;6(3):13-18. Epub 2019 Dec 16.

Department of Radiation Oncology, University Hospitals Seidman Cancer Center at Case Western Reserve University, Cleveland, OH, USA.

Purpose: Reirradiation in the scalp area can be challenging given the proximity to organs at risk (OARs), such as the eye and brain. Our aim is to evaluate the dosimetric differences of volumetric modulated arc therapy (VMAT) and electron beam therapy (EBT) compared with 3-dimensional proton beam therapy (PBT).

Patients And Methods: We evaluated a patient with recurrent angiosarcoma of the left temporal scalp after prior surgical resections and radiation therapy to 60 Gy in 30 fractions who needed reirradiation. Read More

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http://dx.doi.org/10.14338/IJPT-19-00074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038915PMC
December 2019

Outcomes in patients with lacrimal gland carcinoma treated with definitive radiotherapy or eye-sparing surgery followed by adjuvant radiotherapy.

Radiat Oncol 2020 Jun 22;15(1):156. Epub 2020 Jun 22.

Department of Electro-Optical Engineering, National Taipei University of Technology, 1, Sec. 3, Chung-Hsiao E. Rd, Taipei, 10608, Taiwan, ROC.

Background: The optimal treatment for lacrimal gland cancer remains unclear. Eye-preserving surgery, as opposed to exenteration, followed by adjuvant radiotherapy (RT), has recently been reported to deliver satisfactory outcomes, but evidence is sparse. The aim of the present study was to evaluate outcomes in patients with lacrimal gland cancer treated at two tertiary medical centers. Read More

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http://dx.doi.org/10.1186/s13014-020-01601-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310012PMC

Orbital solitary fibrous tumors: a multi-centered histopathological and immunohistochemical analysis with radiological description.

Ann Saudi Med 2020 May-Jun;40(3):227-233. Epub 2020 Jun 4.

From the Department of Neuroscience, School of Medicine and Surgery, University of Naples Federico II, Napoli, Campania, Italy.

Background: Solitary fibrous tumors (SFT), formerly called hemangiopericytoma, are rare tumors derived from mesenchymal cells originally described in the pleura, but these tumors may affect extraserosal tissues including the lacrimal gland and orbit.

Objective: Conduct a multi-centered clinical, radiological and histopathological analysis of 17 orbital SFT cases.

Design: A retrospective case series. Read More

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http://dx.doi.org/10.5144/0256-4947.2020.227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270616PMC

[Clinical and pathological analysis of 64 patients with primary neoplasms of the lacrimal drainage system].

Zhonghua Yan Ke Za Zhi 2020 May;56(5):364-369

Tianjin Eye Hospital, Tianjin Key Lab. of Ophthalmology and Visual Science, Nankai University Affiliated Eye Hospital, Clinical College of Ophthalmology of Tianjin Medical University, Tianjin Eye Institute, Tianjin 300020, China.

To analyze the pathological classification and age distribution of primary neoplasms of the lacrimal drainage system. Retrospective case series study. A total of 64 patients (65 eyes) were diagnosed with primary neoplasms of the lacrimal drainage system and received surgery at Tianjin Eye Hospital from January 2006 to December 2016. Read More

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http://dx.doi.org/10.3760/cma.j.cn112142-20190414-00216DOI Listing

Value of quantitative multiparametric MRI in differentiating pleomorphic adenomas from malignant epithelial tumors in lacrimal gland.

Neuroradiology 2020 May 19. Epub 2020 May 19.

Department of Radiology, Beijing Tongren Hospital, Capital Medical University, No. 1, Dongjiaominxiang, Dongcheng District, Beijing, 100730, China.

Purpose: To evaluate the diagnostic performance of the quantitative parameters derived from diffusion-weighted imaging (DWI) and dynamic contrast-enhanced (DCE) MRI in differentiating lacrimal gland pleomorphic adenomas (LGPAs) from lacrimal gland malignant epithelial tumors (LGMETs).

Methods: Seventy-seven cases with LG epithelial tumors confirmed by histopathology (47 LGPAs and 30 LGMETs) underwent DWI and DCE-MRI. The quantitative parameters including the apparent diffusion coefficient (ADC), the volume transfer constant (K), the efflux rate constant from the extravascular extracellular space (EES) to blood plasma (K), and the extravascular extracellular volume fraction (V) were used to differentiate LGPAs from LGMETs. Read More

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http://dx.doi.org/10.1007/s00234-020-02455-3DOI Listing

Palpebral Pleomorphic Adenomas of the Lacrimal Gland.

Ophthalmic Plast Reconstr Surg 2020 May 4. Epub 2020 May 4.

Adnexal Service, Moorfields Eye Hospital, London, United Kingdom.

Aims: To report the characteristics and management for patients with palpebral pleomorphic adenoma of the lacrimal gland.

Methods: The records for patients with palpebral pleomorphic adenoma seen at Moorfields Eye Hospital between 1978 and 2019 were reviewed for demographics, presentation, imaging, histopathology, management, and outcome.

Results: Forty-three patients (25 male; 58%) with palpebral pleomorphic adenoma were identified, presenting at a mean age of 46 years (median 46. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001682DOI Listing

Epithelial-Myoepithelial Carcinoma of the Lacrimal Sac and Literature Review of the Lacrimal System.

Allergy Rhinol (Providence) 2020 Jan-Dec;11:2152656720920600. Epub 2020 Apr 20.

Department of Otolaryngology-Head and Neck Surgery, Indiana University School of Medicine, Indianapolis, Indiana.

Background: Epithelial-myoepithelial carcinomas make up less than 0.1% of head and neck malignancies and are regarded as rare, low-grade malignant neoplasms of the salivary gland. They are thought to arise from intercalated ducts with histopathology showing a classic biphasic morphology of an outer layer of myoepithelial cells and inner layer of epithelial cells. Read More

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http://dx.doi.org/10.1177/2152656720920600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175067PMC

Epithelial-Myoepithelial Carcinoma of the Lacrimal Gland: Case Report of Youngest Patient.

Ophthalmic Plast Reconstr Surg 2020 Apr 17. Epub 2020 Apr 17.

Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences.

The authors report a case of extremely uncommon malignancy of lacrimal gland epithelial-myoepithelial carcinoma. This carcinoma is more commonly encountered in salivary glands and comprises 1% of all salivary gland tumors. Its occurrence in the orbit is very rare with only 6 cases reported in the literature, most of which arose in a pleomorphic adenoma. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001663DOI Listing

Mucoepidermoid Carcinoma of the Lacrimal Sac: Clinical-Pathologic Analysis, Including Molecular Genetics.

Ocul Oncol Pathol 2020 Mar 20;6(2):138-144. Epub 2019 Sep 20.

Department of Ophthalmology, Wills Eye Hospital, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

Purpose: The aim of this study was to assess whether mucoepidermoid carcinoma of the lacrimal sac is a counterpart of gene fusion-related salivary gland mucoepidermoid carcinoma.

Methods: In this retrospective observational case series, pathology records were searched for all cases of lacrimal sac mucoepidermoid carcinoma diagnosed between 1990 and 2018. Data collected included demographics, clinical findings, management, and follow-up. Read More

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http://dx.doi.org/10.1159/000502699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109434PMC

HPV may not play a role in all lacrimal transitional cell papilloma.

Rhinology 2020 Apr 6. Epub 2020 Apr 6.

Royal National Throat, Nose and Ear Hospital, London, UK.

Background: Tumours of the lacrimal duct apparatus (LDA) are rare and heterogenous but knowledge of their aetiology is important for the rhinologist. A link between transitional cell papilloma/carcinoma (TCP/TCC) and human papilloma virus (HPV) has been suggested in previous studies. We aimed to add to this body of evidence by submitting 16 LDA tumour samples from our tertiary referral centre for HPV analysis. Read More

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http://dx.doi.org/10.4193/Rhin19.283DOI Listing

Orbital manifestations of granulomatosis with polyangiitis: 12-year experience in Mexico City.

Orbit 2020 Mar 13:1-8. Epub 2020 Mar 13.

Oculoplastics Department, Instituto de Oftalmologia Fundacion Conde de Valenciana IAP, Mexico City, Mexico.

: To present the clinical picture and radiological characteristics of orbital manifestations of granulomatosis with polyangiitis in a Mexican hospital and compare them with worldwide literature.: Retrospective, observational study from January 2007 to January 2019. An electronic file review was performed. Read More

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http://dx.doi.org/10.1080/01676830.2020.1737717DOI Listing

Pilomatrix carcinoma of the lacrimal caruncle: a case report.

Arq Bras Oftalmol 2020 Mar-Apr;83(2):153-156

Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA.

A 45-year-old man presented with a 3-month history of a mass located in the caruncle of his right eye. An incisional biopsy had been performed one month prior by another specialist, and the histopathology report showed basal cell carcinoma. The mass was completely excised with a 2 mm safety margin, and the large conjunctival defect was reconstructed with one sheet of amniotic membrane allograft. Read More

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http://dx.doi.org/10.5935/0004-2749.20200029DOI Listing

Clinical-dosimetric relationship between lacrimal gland dose and keratoconjunctivitis sicca in dogs with sinonasal tumors treated with radiation therapy.

J Vet Intern Med 2020 Mar 22;34(2):867-872. Epub 2020 Feb 22.

Department of Medical Physics, Grand River Regional Cancer Centre, Kitchener, Ontario, Canada.

Background: Dogs with sinonasal tumor can develop keratoconjunctivitis sicca (KCS) after radiation therapy (RT). In humans, the incidence of xerophtalmia is associated with the mean radiation dose received by the ipsilateral lacrimal gland (LG).

Hypothesis/objectives: The eyes receiving a higher mean LG dose are more likely to develop KCS. Read More

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http://dx.doi.org/10.1111/jvim.15744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096656PMC

Periorbital squamous cell carcinoma with simultaneous adenocarcinoma in the right orbit.

Int J Surg Case Rep 2020 6;67:187-190. Epub 2020 Feb 6.

Northwick Park Hospital London, HA1 3UJ, United Kingdom. Electronic address:

Introduction: Cutaneous squamous cell carcinoma (cSCC) is an invasive and malignant tumour that is common in the orbital region. However, adenocarcinoma of the lacrimal gland has an incidence of less than one case per million per year. We present a patient who experienced a cSCC and adenocarcinoma of the lacrimal gland, which is unusual for both these cancers to present in the same patient in such close proximity. Read More

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http://dx.doi.org/10.1016/j.ijscr.2020.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025094PMC
February 2020

Concomitant Orbital Tumours: Small Lymphocytic Lymphoma Involving the Lacrimal Gland of a Patient with Clinical Diagnoses of Muir-Torre Syndrome and Extensive Sebaceous Gland Carcinoma of the Ipsilateral Eyelid.

Ocul Oncol Pathol 2020 Jan 5;6(1):15-19. Epub 2019 Jun 5.

Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, United Kingdom.

Background/aims: We present a case of 2 concomitant tumours, i.e., a sebaceous carcinoma (SC) and a small lymphocytic lymphoma (SLL), in the lacrimal gland of a patient with Muir-Torre syndrome

Methods: Clinical history, orbital examination, diagnostic biopsy, excisional biopsy, and histopathologic analysis were utilized. Read More

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http://dx.doi.org/10.1159/000500161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984142PMC
January 2020

A Rare Pediatric Case of Lacrimal Gland Pleomorphic Adenoma.

Plast Reconstr Surg Glob Open 2019 Sep 23;7(9):e2435. Epub 2019 Sep 23.

Division of Pediatric Plastic Surgery, Children's National Health System.

Pleomorphic adenoma of the lacrimal gland is a rare benign finding in adults, and extremely uncommon in children. These tumors often present with increased propotosis or hypoglobus, and they invariably require operative excision. While many of these lesions can be removed through a subcranial or transorbital exposure, larger and more posterior tumors occasionally necessitate an intracranial approach. Read More

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http://dx.doi.org/10.1097/GOX.0000000000002435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908400PMC
September 2019

[Retrospective investigation of spontaneous bloody tears: a report of 27 cases].

Zhonghua Yan Ke Za Zhi 2020 Jan;56(1):53-58

Lacrimal Centre of Ophthalmology, the Third Medical Center, Chinese PLA General Hospital, Beijing 100039, China.

To summarize clinical experience on the clinical feature, etiology and treatment of patients with spontaneous bloody tears as the initial symptom. Retrospective series of case studies. The clinical data and follow-up data of 27 cases of bloody tears as the first symptom in Lacrimal Center of Ophthalmology, the Third Medical Center of Chinese PLA General Hospital from June 2015 to December 2018 were reviewed. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0412-4081.2020.01.013DOI Listing
January 2020

[Does orbital exenteration still has a place in 2019?]

J Fr Ophtalmol 2020 Feb 9;43(2):152-174. Epub 2019 Dec 9.

Service de chirurgie oncologique cervico-faciale, centre Antoine Lacassagne, 06189 Nice, France.

Introduction: Orbital exenteration is a radical anatomically and psychologically disfiguring procedure. It is mostly performed for management of orbital cancers or cancers with orbital involvement. The lack of benefit in terms of overall survival and the development of new molecular therapies (targeted therapies, immunotherapy) in recent years leads us to question its use. Read More

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http://dx.doi.org/10.1016/j.jfo.2019.04.021DOI Listing
February 2020

[Clinical application of modified kite flap in treatment of divided nevus of lateral canthus].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2019 Dec;33(12):1556-1559

Department of Plastic Surgery, the First Affiliated Hospital of Nanchang University, Nanchang Jiangxi, 330006, P.R.China.

Objective: To investigate the effectiveness of modified kite flap in repair of soft tissue defect after divided nevus of lateral canthus excision.

Methods: Between October 2010 and April 2018, 20 children (20 eyes) with divided nevus of lateral canthus were admitted. There were 13 boys and 7 girls, with an average age of 7. Read More

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http://dx.doi.org/10.7507/1002-1892.201905012DOI Listing
December 2019

Mohs Surgery for Periocular Tumors.

Dermatol Surg 2019 12;45 Suppl 2:S70-S78

Total Skin and Beauty Dermatology Center, Birmingham, Alabama.

Background: Skin cancers of the periorbital area present unique challenges to Mohs surgeons.

Objective: The need for precise and high-quality Mohs micrographic surgery (MMS) is paramount because of the complex anatomy, vital structures, and potential threat to vision.

Methods: A thorough comprehension of anatomy is essential to help predict tumor behavior and ensure successful outcomes for patients. Read More

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http://dx.doi.org/10.1097/DSS.0000000000002254DOI Listing
December 2019

Clinical Management of Acinic Cell Carcinoma of the Lacrimal Gland.

Case Rep Oncol 2019 Sep-Dec;12(3):777-790. Epub 2019 Oct 16.

Cranio-Maxillo-Facial Surgery Unit, University Hospital of Modena, Modena, Italy.

To report a case of acinic cell carcinoma occurred in the lacrimal gland. A 59-year-old man was admitted because of sudden blurring of vision, progressive proptosis of the left eye, and mild double vision in left and down directions of the gaze (Hess-Lancaster test). His medical history detailed controlled bilateral keratoconus and open angle glaucoma. Read More

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http://dx.doi.org/10.1159/000503557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872994PMC
October 2019

Role of F-18 FDG PET/CT in non-conjunctival origin ocular adnexal mucosa-associated lymphoid tissue (MALT) lymphomas.

EJNMMI Res 2019 Nov 21;9(1):99. Epub 2019 Nov 21.

Department of Ophthalmology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, Seoul, 06591, Republic of Korea.

Background: Despite the widespread use of F-18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) in the diagnosis and response assessment of patients with lymphoma, few studies have assessed its value in ocular adnexal lymphomas. The purpose of this study was to evaluate the role of FDG PET/CT in staging of non-conjunctival origin ocular adnexal mucosa-associated lymphoid tissue (MALT) lymphomas (OAML). In addition, the diagnostic sensitivity of FDG PET/CT was compared with magnetic resonance imaging (MRI). Read More

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http://dx.doi.org/10.1186/s13550-019-0562-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872696PMC
November 2019

Dose distribution of intensity-modulated proton therapy with and without a multi-leaf collimator for the treatment of maxillary sinus cancer: a comparative effectiveness study.

Radiat Oncol 2019 Nov 21;14(1):209. Epub 2019 Nov 21.

Departments of Radiology, Dentistry and Pharmaceutical Science, Okayama University Graduate School of Medicine, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8558, Japan.

Background: Severe complications, such as eye damage and dysfunciton of salivary glands, have been reported after radiotherapy among patients with head and neck cancer. Complications such as visual impairment have also been reported after proton therapy with pencil beam scanning (PBS). In the case of PBS, collimation can sharpen the penumbra towards surrounding normal tissue in the low energy region of the proton beam. Read More

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http://dx.doi.org/10.1186/s13014-019-1405-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873663PMC
November 2019

Intracapsular High-Grade Ductal Carcinoma In-Situ Ex Pleomorphic Adenoma of the Lacrimal Gland.

Ophthalmic Plast Reconstr Surg 2020 Jan/Feb;36(1):e1-e3

Department of Ophthalmology, University of California, San Francisco.

Primary ductal adenocarcinoma of the lacrimal gland is an aggressive neoplasm and can be seen either as a de novo malignancy or in the setting of a carcinoma ex pleomorphic adenoma. Carcinoma ex pleomorphic adenoma carries an overall unfavorable outcome; however, prognosis depends on the type and grade of the malignant component, presence of retained myoepithelial component, and extend of invasion beyond the capsule. Herein, the authors describe a 78-year-old man diagnosed with an incidental, intracapsular, high-grade ductal adenocarcinoma in situ ex pleomorphic adenoma, who is free of disease at 9 months subsequent to complete resection. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001491DOI Listing
November 2019

[A clinicopathological classification analysis of ocular mass lesions in 7 910 cases].

Zhonghua Yan Ke Za Zhi 2019 Nov;55(11):847-853

Department of Ophthalmology, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.

To investigate the anatomical region, histopathological classification and histogensis distribution of ocular mass lesions in South China. Retrospective cases study. The clinical and pathological data of 7 910 samples with ocular (adnexal) tumors or proliferative lesions which were examined from January 2000 to May 2018 were retrospectively retrieved. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0412-4081.2019.11.011DOI Listing
November 2019

[Clinical features and pathological analysis of lacrimal gland occupying lesions in 91 cases].

Zhonghua Yan Ke Za Zhi 2019 Nov;55(11):842-846

Department of Ophthalmology, the Second People's Hospital of Yunnan Province, Yunnan Clinical Medical Research Center of Eye Diseases, Yunnan Clinical Medical Center of Eye Diseases, Kunming 650021, China.

To analyze the pathogenesis, histopathological classification and clinical features of lacrimal gland occupying lesions. This was a retrospective case series study. Clinical data of 91 patients (102 eyes) with lacrimal gland area occupying diseases who received ophthalmic surgery in the Second People's Hospital of Yunnan Province from January 2014 to November 2018 were retrospectively analyzed, including patients' age, reasons for treatment, gender, imageological examination data and pathological diagnosis results. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0412-4081.2019.11.010DOI Listing
November 2019

[Clinical features and surgical management of orbitotemporal neurofibromatosis].

Zhonghua Yan Ke Za Zhi 2019 Nov;55(11):828-833

Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Science Key Lab., Beijing 100730, China.

To report the clinical features and surgical treatment of orbitotemporal neurofibromatosis. It was a retrospective case series study. The clinical records of 24 patients who were treated for orbitotemporal neurofibromatosis between April 2007 and July 2017 at Beijing Tongren Hospital, Capital Medical University were analyzed. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0412-4081.2019.11.008DOI Listing
November 2019

Intraductal carcinomas of the salivary glands: systematic review and classification of 93 published cases.

Authors:
Andrea Palicelli

APMIS 2020 Mar 3;128(3):191-200. Epub 2020 Jan 3.

Pathology Unit, Azienda Unità Sanitaria Locale-IRCCS, Reggio Emilia, Italy.

Intraductal carcinomas (IDCs) are rare, not well-characterized salivary gland tumors. A systematic literature review of pure IDCs (without stromal invasion) of low-grade (LG-IDCs) or high-grade (HG-IDCs) was performed: IDCs were classified using the apocrine (AR+/S100-) vs intercalated (S100+/AR-) classification. Eighty-two LG-IDCs and 11 HG-IDCs were identified (84% parotid; 11% oral; 3% submandibular; 1% lacrimal; and 1% unknown). Read More

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http://dx.doi.org/10.1111/apm.13009DOI Listing

[Transcanalicular endoscopy of the lacrimal pathways].

Vestn Oftalmol 2019 ;135(4):78-82

Cheboksary branch of S.N. Fyodorov National Medical Research Center 'MNTK 'Eye Microsurgery', 10 Traktorostroiteley Pr., Cheboksary, Chuvash Republic, Russian Federation, 428028.

Purpose: To study the clinical significance of the method of transcanalicular dacryo-endoscopy, and to determine its place in the system of diagnostic and therapeutic measures for obstruction of lacrimal ducts (dacryostenosis).

Material And Methods: Transcanalicular endoscopy was performed in 44 patients aged 24 to 65 years with complaints characteristic of dacryostenosis on the equipment manufactured by 'Machida Endoscope Co., Ltd' (Japan). Read More

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http://dx.doi.org/10.17116/oftalma201913504178DOI Listing
October 2019

Dacryops - A review.

Orbit 2020 Apr 12;39(2):128-134. Epub 2019 Sep 12.

Department of Ophthalmology, University of California, San Francisco, California, USA.

: To review and summarize the epidemiology, clinical presentations, histopathologic characteristics and management of dacryops.: A comprehensive PubMed, Embase and Google Scholar search of all articles written in English and non-English language articles with abstract translated to English on dacryops were reviewed. Data reviewed included epidemiology, etiology, pathogenesis, clinical presentations, histopathologic characteristics and management of dacryops. Read More

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http://dx.doi.org/10.1080/01676830.2019.1608564DOI Listing
April 2020
1 Read

Long-term outcome, relapse patterns, and toxicity after radiotherapy for orbital mucosa-associated lymphoid tissue lymphoma: implications for radiotherapy optimization.

Jpn J Clin Oncol 2019 Jul;49(7):664-670

Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, Republic of Korea.

Objectives: Although mucosa-associated lymphoid tissue lymphoma (MALToma) is sensitive to radiation therapy (RT), the optimal RT dose and treatment volumes have not been established. This study aimed to assess the relapse patterns and outcomes of patients with orbital MALToma who underwent RT and to suggest implications for optimized RT.

Methods: We reviewed 212 patients (246 orbits) diagnosed with orbital MALToma who received RT between 1993 and 2013. Read More

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http://dx.doi.org/10.1093/jjco/hyz044DOI Listing
July 2019
1 Read
1.747 Impact Factor

Mucosa-associated lymphoid tissue lymphoma of the accessory parotid gland presenting as a simple cheek mass: A case report.

Medicine (Baltimore) 2019 Sep;98(36):e17042

Rationale: Mucosa-associated lymphoid tissue (MALT) lymphoma, also known as extranodal marginal zone B-cell lymphoma, usually occurs in the gastric mucosa, lung, lacrimal glands, and salivary glands. MALT lymphoma arising from the accessory parotid gland is extremely rare and can therefore be easily confused with other types of soft tissue masses.

Patient Concerns: A 56-year-old woman presented with a 1-month history of a mass on the left cheek. Read More

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http://dx.doi.org/10.1097/MD.0000000000017042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739029PMC
September 2019
3 Reads

Orbital metastasis from a gastrointestinal stromal tumor: A case report.

Am J Ophthalmol Case Rep 2019 Dec 3;16:100528. Epub 2019 Aug 3.

Department of Ophthalmology, Yijishan Hospital of Wannan Medical College, Wuhu, 241000, China.

Background: Gastrointestinal stromal tumor (GIST) is the most common primary mesenchymal tumor. The most common metastasis sites are the liver and the surface of the peritoneum. In this study, we present a case of orbital GIST metastasis. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.100528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699248PMC
December 2019
2 Reads

Effect of Eyelid Involvement in the Reconstruction of Medial Canthal Defects.

Facial Plast Surg 2019 Aug 9;35(4):410-419. Epub 2019 Aug 9.

Department of Ophthalmology, Izmir Katip Celebi University Ataturk Training and Research Hospital, Izmir, Turkey.

The purpose of this study was to present surgical techniques for the reconstruction of medial canthal defects with and without the involvement of the eyelid. This study included 31 patients who underwent medial canthal reconstruction after tumor excision during a 6-year period. Data regarding patient demographics, defect size, tumor pathology, surgery techniques, functional and cosmetic outcomes, and complications were recorded. Read More

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http://dx.doi.org/10.1055/s-0039-1694722DOI Listing
August 2019
5 Reads

Lacrimal drainage system stenosis associated with Trastuzumab emtansine (Kadcyla®, T-DM1) administration: a case report.

BMC Cancer 2019 Aug 6;19(1):774. Epub 2019 Aug 6.

Department of Ophthalmology, College of Medicine, Seoul National University, Seoul, South Korea.

Background: Trastuzumab emtansine (Kadcyla®, T-DM1) is an antibody-drug conjugate used to treat HER2 (human epidermal growth factor receptor 2) overexpressing metastatic breast cancer. In this report, we present the first case of lacrimal drainage system stenosis identified after T-DM1 administration, and its successful treatment with a topical steroid.

Case Presentation: A 36-year-old female with metastatic breast cancer was referred for excessive tearing of both eyes. Read More

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http://dx.doi.org/10.1186/s12885-019-5986-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683558PMC
August 2019
6 Reads

Dacryoadenitis Caused by Blastomycosis: A Case Report.

Ophthalmic Plast Reconstr Surg 2019 Sep/Oct;35(5):e116-e118

Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, U.S.A.

This is the first case of histopathologically proven blastomycosis involving the lacrimal gland. A 51-year-old woman with a history of disseminated blastomycosis involving her lungs and skin, on oral itraconazole, presented with 3 days of right upper eyelid swelling, erythema, and pain concerning for recurrent dacryoadenitis. MRI showed enlargement of the right lacrimal gland with a cystic lesion at the anterior aspect of the gland with a radiographic differential diagnosis of abscess versus cyst. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001445DOI Listing
January 2020
4 Reads

A Case of Lacrimal Gland Ductal Carcinoma With Regional Lymph Node Metastasis.

Ophthalmic Plast Reconstr Surg 2019 Sep/Oct;35(5):e118-e121

Department of Ophthalmology, University of California San Francisco, San Francisco, California, U.S.A.

Ductal carcinoma of the lacrimal gland is a very rare and aggressive neoplasm, with clinical and histopathologic similarities to salivary ductal carcinoma. Of the 25 previously reported cases, 2 patients had metastases to local lymph nodes confirmed on pathologic examination. The authors now report the clinical presentation, histopathologic and immunohistochemical features, and the treatment of a third patient with lacrimal gland ductal carcinoma with spread to local lymph nodes. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001447DOI Listing
January 2020
3 Reads

Prospective Assessment of Patient-Reported Dry Eye Syndrome After Whole Brain Radiation.

Int J Radiat Oncol Biol Phys 2019 11 24;105(4):765-772. Epub 2019 Jul 24.

Department of Radiation Oncology, University of North Carolina Hospitals, Chapel Hill, North Carolina.

Purpose: Dry eye is not typically considered a toxicity of whole brain radiation therapy (WBRT). We analyzed dry eye syndrome as part of a prospective study of patient-reported outcomes after WBRT.

Methods And Materials: Patients receiving WBRT to 25 to 40 Gy were enrolled on a study with dry mouth as the primary endpoint and dry eye syndrome as a secondary endpoint. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03603016193349
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http://dx.doi.org/10.1016/j.ijrobp.2019.07.015DOI Listing
November 2019
3 Reads

Cluster of differentiation 30 expression in lacrimal gland and conjunctival tissues in patients with Sjögren's syndrome: Case series.

Medicine (Baltimore) 2019 Jul;98(29):e16390

Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.

Introduction: Sjögren's syndrome (SS) often causes lymphoproliferative disorders such as malignant lymphoma and macroglobrinemia. Approximately 5% of long-term follow-up SS patients develop malignant lymphoma. Recently, the tumor necrosis factor receptor superfamily cluster of differentiation 30 (CD30) has been thought to be implicated in malignant cells in organs affected by Hodgikin lymphoma or in a prognostic marker of diffuse large B cell lymphoma. Read More

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http://dx.doi.org/10.1097/MD.0000000000016390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708891PMC
July 2019
3 Reads

Bilateral Lacrimal Sac Swelling in a Newborn.

Neoreviews 2019 04;20(4):e242-e244

Department of Pediatrics, Centro Hospitalar Oeste, Caldas da Rainha, Portugal.

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http://dx.doi.org/10.1542/neo.20-4-e242DOI Listing
April 2019
5 Reads

Primary lacrimal gland teratoma in an adult: A clinicopathologic and radiological correlation.

Indian J Ophthalmol 2019 07;67(7):1238-1240

Ocular Pathology Service, Centre for Sight, Asoka Capitol Building, Road No 2, Banjara Hills, Hyderabad, Telangana, India.

A 20-year-old male presented with a gradually growing mass in the left lateral brow region for 2 years. On imaging, the mass appeared to arise from the lacrimal gland, was cystic, without any bony abnormality. With a diagnosis of dermoid cyst, an excision biopsy was performed. Read More

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http://dx.doi.org/10.4103/ijo.IJO_1764_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611252PMC
July 2019
4 Reads
0.927 Impact Factor

Cystic appearance - a new feature of solid fibrous tumours in the lacrimal gland: a case report with literature review.

Diagn Pathol 2019 Jun 22;14(1):63. Epub 2019 Jun 22.

Department of Endocrinology, "Carol Davila" University of Medicine and Pharmacy, 050474, Bucharest, Romania.

Background: Solitary fibrous tumours (SFTs) rarely occur in the orbit, especially in the lacrimal area. These tumours are mostly solid. Cystic changes have been documented, but they remain very rare. Read More

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http://dx.doi.org/10.1186/s13000-019-0845-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589176PMC
June 2019
6 Reads

Efficacy of PROPELLER in reducing ocular motion artefacts and improving image quality of orbital MRI at 3 T using an eye surface coil.

Clin Radiol 2019 Sep 17;74(9):734.e7-734.e12. Epub 2019 Jun 17.

Clinical Center for Eye Tumors, Capital Medical University, Beijing 100730, China; Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.

Aim: To evaluate the efficacy of periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) in reducing ocular motion artefacts and improving image quality of orbital magnetic resonance imaging (MRI) at 3 T using an eye surface coil.

Materials And Methods: Forty-six patients underwent orbital 3 T MRI using an eye surface coil. The pre-contrast axial T2-wighted (W) PROPELLER and T1 fluid-attenuated inversion recovery (FLAIR) PROPELLER imaging were performed on 21 patients, and conventional T2W and T1W imaging were performed on 25 patients. Read More

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http://dx.doi.org/10.1016/j.crad.2019.05.014DOI Listing
September 2019
5 Reads

Isolated Langerhans Cell Histiocytosis of the Lacrimal Gland in Conjunction With Mucosa-Associated Lymphoid Tissue Lymphoma and Elevated IgG4 Plasma Cells.

Ophthalmic Plast Reconstr Surg 2019 Jul/Aug;35(4):e92-e94

Department of Ophthalmology, Wills Eye Hospital, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania, U.S.A.

Langerhans cell histiocytosis (LCH) is a clonal neoplastic proliferation of Langerhans-type cells. Orbital LCH is infrequent, typically manifesting as an isolated lytic bony lesion with an adjacent soft tissue mass in a child. Isolated lacrimal gland involvement by LCH is extremely rare, with only 2 previously reported cases. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001399DOI Listing
December 2019
11 Reads

Multimodal therapy in the management of lacrimal gland adenoid cystic carcinoma.

BMC Ophthalmol 2019 Jun 8;19(1):125. Epub 2019 Jun 8.

Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, 639 Zhi Zao Ju Road, Shanghai, 200011, China.

Background: To evaluate the prognosis of Chinese patients with lacrimal gland adenoid cystic carcinoma treated with eye-sparing surgery and adjuvant multimodal therapy.

Methods: The study included 24 consecutive patients with lacrimal gland adenoid cystic carcinoma treated at the Ninth People's Hospital of Shanghai from May 2008 to September 2017. All patients underwent eye-sparing surgical tumor resection and 20 (83. Read More

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http://dx.doi.org/10.1186/s12886-019-1110-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556222PMC
June 2019
19 Reads

[Clinical analysis of adult onset orbital xanthogranuloma].

Zhonghua Yan Ke Za Zhi 2019 May;55(5):381-386

Tianjin Medical University Eye Hospital, College of Optometry and Ophthalmology, Tianjin Medical University Eye Institute, Tianjin 300384, China.

To investigate the clinical, imaging and pathological features of adult onset xanthogranuloma. Retrospective case series study.The clinical data of 4 adult patients with adult onset xanthogranuloma treated in the Tianjin Medical University Eye Hospital from 2015 to 2017 were analyzed. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0412-4081.2019.05.013DOI Listing
May 2019
15 Reads

Survival outcomes of eye-sparing surgery for adenoid cystic carcinoma of lacrimal gland.

Jpn J Ophthalmol 2019 Jul 27;63(4):344-351. Epub 2019 May 27.

Department of Ophthalmology, National Taiwan University Hospital, No. 7, Zhongshan S. Rd., Zongzheng Dist., Taipei City, Taiwan.

Purpose: To survey adenoid cystic carcinoma of lacrimal glands in Asian population and investigate the predictability in prognosis following the 8 edition American Joint Committee on Cancer (AJCC) staging guideline.

Study Design: Retrospective study.

Methods: The clinical entities and surgical outcomes of the patients who were histologically confirmed with a diagnosis of lacrimal adenoid cystic carcinoma in National Taiwan University Hospital between January 1995 and December 2015 were retrospectively reviewed. Read More

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http://link.springer.com/10.1007/s10384-019-00671-w
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http://dx.doi.org/10.1007/s10384-019-00671-wDOI Listing
July 2019
11 Reads

Nasolacrimal Duct Management During Endoscopic Sinus and Skull Base Surgery.

Ann Otol Rhinol Laryngol 2019 Oct 14;128(10):932-937. Epub 2019 May 14.

1 Department of Otolaryngology-Head and Neck Surgery, New York University Langone Health, NY, USA.

Objective: To evaluate rates of epiphora after transection and marsupialization of the nasolacrimal duct (NLD) during endoscopic sinus and skull base surgery.

Introduction: The nasolacrimal canal forms part of the medial wall of the maxillary sinus. Transecting the NLD is sometimes necessary for tumor resection or surgical access to maxillary sinus and infratemporal fossa pathology. Read More

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http://dx.doi.org/10.1177/0003489419848454DOI Listing
October 2019
12 Reads

Awake bedside nasal endoscopy for primary management of neonatal dacryocystoceles with intranasal cysts.

Int J Pediatr Otorhinolaryngol 2019 Aug 6;123:93-96. Epub 2019 May 6.

Department of Otolaryngology - Head and Neck Surgery, University of California - San Francisco, San Francisco, CA, USA. Electronic address:

Objective: To present outcomes of neonatal dacryocystoceles treated through endoscopic intranasal cyst marsupialization (EICM) without general anesthesia and nasolacrimal duct (NLD) probing or irrigation.

Methods: Records of eleven consecutive infants diagnosed with unilateral or bilateral congenital cysts associated with the nasolacrimal system between January 2016 and February 2019 at our institution were retrospectively reviewed.

Results: Age at diagnosis ranged from 0 to 56 days, and 45. Read More

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http://dx.doi.org/10.1016/j.ijporl.2019.04.043DOI Listing
August 2019
9 Reads