1,863 results match your criteria Labor and Delivery Normal Delivery of the Newborn

Maternal overweight but not paternal overweight before pregnancy is associated with shorter newborn telomere length: evidence from Guangxi Zhuang birth cohort in China.

BMC Pregnancy Childbirth 2021 Apr 9;21(1):283. Epub 2021 Apr 9.

Department of Epidemiology and Health Statistics, School of Public Health, Guangxi Medical University, No. 22 Shuangyong Road, Nanning, 530021, Guangxi, China.

Background: Telomere length (TL) is variable at birth and is inversely associated with body mass index (BMI) in adulthood. A growing number of evidences suggested that a higher maternal pre-pregnancy BMI results in adverse offspring health outcomes, especially shorter newborn TL. However, a newborn's genetic endowment is equally derived from both parents, the association between parental pre-pregnancy BMI and newborn TL has been rarely discussed. Read More

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Effect of Delivery by Emergency or Elective Cesarean Section on Nitric Oxide Metabolites and Cortisol Amniotic Concentrations in at Term Normal Newborn Dogs: Preliminary Results.

Animals (Basel) 2021 Mar 5;11(3). Epub 2021 Mar 5.

Department of Veterinary Medicine, Università degli Studi di Milano, 26900 Lodi, Italy.

The neonatal response to stress was reported to be related to the type of delivery, that is elective or emergency cesarean sections (ELCS and EMCS, respectively). Nitric oxide (NO) is also reported to be related to uterine inertia, and high levels of NO metabolites (NOs) are associated with physical and emotional stress. The study aimed to assess the concentrations of cortisol (C) and NOs in the amniotic fluid of puppies delivered by ELCS or EMCS. Read More

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Situs Inversus Totalis in the Neonatal Setting.

Cureus 2021 Feb 23;13(2):e13516. Epub 2021 Feb 23.

Neonatology, MedStar Harbor Hospital, Baltimore, USA.

Situs inversus totalis (SIT) is a rare condition of complete inversion and mirroring of normal human anatomy. The incidence is approximately 1 in 8,000 to 1 in 25,000 live births. SIT is inherited in an autosomal recessive pattern and is associated with multiple gene mutations. Read More

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February 2021

Consequences of the SARS-CoV-2 pandemic in the perinatal period.

Mark L Hudak

Curr Opin Pediatr 2021 04;33(2):181-187

University of Florida College of Medicine, Jacksonville, Florida, USA.

Purpose Of Review: To provide an update on the consequences of severe acute respiratory syndrome (SARS)-CoV-2 infection on the health and perinatal outcomes of pregnant women and their infants.

Recent Findings: The severity of SARS-CoV-2 infection is greater in pregnant compared to nonpregnant women as measured by rates of admission to intensive care units, mechanical ventilation, mortality, and morbidities including myocardial infarction, venous thromboembolic and other thrombotic events, preeclampsia, preterm labor, and preterm birth. The risk of transmission from mother-to-infant is relatively low (1. Read More

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Quality of maternal and newborn hospital care in Brazil: a quality improvement cycle using the WHO assessment and quality tool.

Int J Qual Health Care 2021 Mar;33(1)

Dottorato di Ricerca in Scienze della Riproduzione e dello Sviluppo, Università degli Studi di Trieste, Piazzale Europa, Trieste 34127, Italy.

Background: Increasing efforts toward quality improvement (QI) are necessary in low- and middle-income countries (LMICs) to reduce maternal and perinatal mortality and morbidity and to promote respectful care. In Brazil, perinatal health indicators are below targets in several states despite universal access to perinatal services and very high rates of institutional births, indicating poor quality of care (QoC) as a key issue to be addressed. However, research efforts to develop and test QoC improvement interventions are scarce. Read More

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Adnexal torsion in pregnancy after in vitro fertilization: Case report and literature review.

Medicine (Baltimore) 2021 Jan;100(3):e24009

Center for Reproductive Medicine and Center for Prenatal Diagnosis, First Hospital, Jilin University, 71 Xinmin Street, Chaoyang District, Changchun, Jilin Province, China.

Rationale: Torsion is the most common gynecologic emergency of the adnexal mass occurring during pregnancy. We report the clinical data of a case of twin pregnancy with adnexal torsion after in vitro fertilization (IVF) and embryo transfer, in which the patient underwent surgery for adnexal detorsion and experienced preterm delivery. One child died as a neonate, and the other child was diagnosed with hematological disease, which, to our knowledge, has not been reported previously. Read More

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January 2021

Monozygotic twins discordant for homologous Robertsonian translocation trisomy 21 of 46, XX, + 21, der (21;21) (q10; q10) in a twin-to-twin transfusion syndrome, case report.

BMC Pregnancy Childbirth 2021 Jan 30;21(1):101. Epub 2021 Jan 30.

Department of Obstetrics and Gynecology, Department of Fetal Medicine and Prenatal Diagnosis, Key Laboratory for Major Obstetric Diseases of Guangdong Province, The Third Affiliated Hospital of Guangzhou Medical University, 63 Duobao Road, Liwan District, Guangzhou, 510150, China.

Background: Monozygotic twins are nearly identical in genotype and phenotype because monozygotic twins arise from one fertilized oocyte. In all cases of discordant karyotype in monozygotic twins, trisomy 21 accounts for about one in 385,000. Monozygotic twins discordant for Robertsonian translocation trisomy 21 of the der (21;21)(q10;q10), in which the additional chromosome originates from the father is rare. Read More

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January 2021

Prediction of Preterm Delivery by Ultrasound Measurement of Cervical Length and Funneling Changes of the Cervix in Pregnant Women with Preterm Labor at 28-34 weeks of Gestation.

J Med Life 2020 Oct-Dec;13(4):536-542

1. Department of Obstetrics and Gynecology, Shahid Akbarabadi Hospital, Iran University of Medical Sciences, Tehran, Iran.

The present study aims at predicting preterm delivery by ultrasound measurement of cervical length and the funneling changes of the cervix in preterm labor pregnant women at 28-34 weeks of gestation. The present study is an observational-analytical study with a prospective cohort design. The statistical population of this study includes 70 preterm labor pregnant women who were referred to Tehran hospitals from March 2018 to March 2020. Read More

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January 2021

Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Twins Compared with Singletons.

South Med J 2021 Jan;114(1):28-31

From the Department of Obstetrics and Gynecology, New York Health + Hospitals/Lincoln, Bronx, New York.

Objectives: It is well known that twin pregnancies confer a high degree of adverse perinatal outcomes. Fetal growth restriction, preterm labor/delivery, and hypertensive disorders of pregnancy are among the causal etiologies associated. Hematologic parameters, specifically, the neutrophil:lymphocyte ratio (NLR), the platelet:lymphocyte ratio (PLR), and some of the routine complete blood cell count components denote a peculiar inflammatory and immunologic profile and have been used as clinical markers for specific obstetric syndromes. Read More

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January 2021

Changes in heart rate from 5 s to 5 min after birth in vaginally delivered term newborns with delayed cord clamping.

Arch Dis Child Fetal Neonatal Ed 2021 May 10;106(3):311-315. Epub 2020 Nov 10.

Department of Paediatrics, Stavanger University Hospital, Stavanger, Norway.

Objective: To determine heart rate centiles during the first 5 min after birth in healthy term newborns delivered vaginally with delayed cord clamping.

Design: Single-centre prospective observational study.

Setting: Stavanger University Hospital, Norway, March-August 2019. Read More

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Effect of sibship asthma on newborns with transient tachypnea of the newborn (TTN).

Zuhal Gundogdu

Clin Respir J 2021 Feb 25;15(2):232-236. Epub 2020 Oct 25.

Child Health and Diseases Department, Faculty of Medicine, Kocaeli University, Kocaeli, Turkey.

Background: A number of studies have demonstrated that transient tachypnea of the newborn (TTN) is a risk factor for later asthma. The present study attempts to determine whether older sibling asthma is a risk factor for TTN.

Methods: Medical records of 1318 newborns from neonatal intensive care and delivery units were studied. Read More

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February 2021

Intrapartum fetal heart rate between 150 and 160 bpm at or after 40 weeks and labor outcome.

Acta Obstet Gynecol Scand 2021 03 1;100(3):548-554. Epub 2020 Nov 1.

Department of Obstetrics and Gynecology, University of Parma, Parma, Italy.

Introduction: A baseline fetal heart rate between 110 and 160 bpm is considered normal. However, among normal fetuses the average baseline heart rate has been shown to diminish progressively and the 90th centile of the fetal heart rate at 40 weeks of gestation has been consistently found at around 150 bpm. The aim of our study was to assess the labor and neonatal outcome of fetuses at 40 gestational weeks or beyond, whose intrapartum baseline fetal heart rate was between 150 and 160 bpm. Read More

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Incidence, Intrapartum Risk Factors, and Prognosis of Neonatal Hypoxic-Ischemic Encephalopathy Among Infants Born at 35 Weeks Gestation or More.

J Obstet Gynaecol Can 2020 Dec 13;42(12):1489-1497. Epub 2020 Jun 13.

Department of Obstetrics & Gynaecology, Dalhousie University, Halifax, NS; Department of Pediatrics, Dalhousie University, Halifax, NS.

Introduction: Neonatal hypoxic-ischemic encephalopathy (HIE) is associated with neonatal mortality, acute neurological injury, and long-term neurodevelopmental disabilities; however, the association between intrapartum factors and HIE remains unclear.

Methods: This population-based cohort study used linked obstetrical and newborn data derived from the Nova Scotia Atlee Perinatal Database (NSAPD, 1988-2015) and the AC Allen Perinatal Follow-Up Program Database (2006-2015) for all pregnancies with live, non-anomalous newborns ≥35 weeks gestation, not delivered by pre-labour cesarean section. Temporal trends in HIE incidence were described, and logistic regression estimated odds ratios (OR) with 95% confidence intervals (CI) for the association of intrapartum factors with HIE. Read More

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December 2020

Trimester-Specific Blood Trihalomethane and Urinary Haloacetic Acid Concentrations and Adverse Birth Outcomes: Identifying Windows of Vulnerability during Pregnancy.

Environ Health Perspect 2020 10 7;128(10):107001. Epub 2020 Oct 7.

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

Background: Some disinfection by-products (DBPs) are reproductive and developmental toxicants in laboratory animals. However, studies of trimester-specific DBP exposure on adverse birth outcomes in humans are inconsistent.

Objective: We examined whether trimester-specific blood and urinary biomarkers of DBP were associated with small for gestational age (SGA), low birth weight (LBW), and preterm birth. Read More

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October 2020

[Normal childbirth: physiologic labor support and medical procedures. Guidelines of the French National Authority for Health (HAS) with the collaboration of the French College of Gynaecologists and Obstetricians (CNGOF) and the French College of Midwives (CNSF) -- Text of the Guidelines (short text)].

Gynecol Obstet Fertil Senol 2020 Dec 1;48(12):873-882. Epub 2020 Oct 1.

Service de gynécologie-obstétrique, maternité Aliénor d'Aquitaine, centre hospitalier universitaire de Bordeaux, place Amélie-Raba-Léon, 33000 Bordeaux, France. Electronic address:

Objective: The objective of these guidelines is to define for women at low obstetric risk modalities that respect the physiology of delivery and guarantee the quality and safety of maternal and newborn care.

Methods: These guidelines were made by a consensus of experts based on an analysis of the scientific literature and the French and international recommendations available on the subject.

Results: It is recommended to conduct a complete initial examination of the woman in labor at admission (consensus agreement). Read More

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December 2020

[Normal childbirth: physiologic labor support and medical procedures. Guidelines of the French National Authority for Health (HAS) with the collaboration of the French College of Gynaecologists and Obstetricians (CNGOF) and the French College of Midwives (CNSF) - Mother's wellbeing and regional or systemic analgesia for labor].

Gynecol Obstet Fertil Senol 2020 Dec 1;48(12):891-906. Epub 2020 Oct 1.

Société française d'anesthésie réanimation, Lille, France; Club d'anesthésie réanimation en obstétrique, Lille, France; Centre hospitalier de Nîmes, 30900 Nîmes, France.

Introduction: These guidelines deal with the parturient wellbeing in terms of hydration and regional and systemic pain management during labour.

Method: Guidelines were established based on literature analysis and experts consensus.

Results: Clear liquids consumption is permitted all along labor and postpartum, without volume limitation, in patients at low risk of general anesthesia (grade B). Read More

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December 2020

[Normal childbirth: physiologic labor support and medical procedures. Guidelines of the French National Authority for Health (HAS) with the collaboration of the French College of Gynaecologists and Obstetricians (CNGOF) and the French College of Midwives (CNSF) - Newborn care in the delivery room].

Gynecol Obstet Fertil Senol 2020 Dec 1;48(12):944-952. Epub 2020 Oct 1.

Pôle femme enfant Victor-Pauchet, 80000 Amiens, France.

Objectives: The purpose of this literature review is to make recommendations regarding the first steps and care provided to the healthy newborn.

Methods: Consultation of the Medline database, and of national and international guidelines.

Results: The initial assessment of the newborn should quickly determine whether resuscitation is necessary or not. Read More

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December 2020

Weekend and off-hour effects on the incidence of cerebral palsy: contribution of consolidated perinatal care.

Environ Health Prev Med 2020 Sep 10;25(1):52. Epub 2020 Sep 10.

Department of the Japan Obstetric Compensation System for Cerebral Palsy, Japan Council for Quality Health Care, Tokyo, Japan.

Objective: This study estimated the effects of weekend and off-hour childbirth and the size of perinatal medical care center on the incidence of cerebral palsy.

Methods: The cases were all children with severe cerebral palsy born in Japan from 2009 to 2012 whose data were stored at the Japan Obstetric Compensation System for Cerebral Palsy database, a nationally representative database. The inclusion criteria were the following: neonates born between January 2009 and December 2012 who had a birth weight of at least 2000 g and gestational age of at least 33 weeks and who had severe disability resulting from cerebral palsy independent of congenital causes or factors during the neonatal period or thereafter. Read More

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September 2020

A CARE-compliant article successful salvage of bilateral perinatal testicular torsion after delivery out of breech presentation: A case report and review of the literature.

Medicine (Baltimore) 2020 Sep;99(36):e21763

Rationale: Neonatal testicular torsion is a rare condition. There is no consensus about the optimal surgical treatment of neonatal testicular torsions. The salvage rate reported in literature remains poor. Read More

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September 2020

Bradycardia-to-delivery interval and fetal outcomes in umbilical cord prolapse.

Acta Obstet Gynecol Scand 2021 01 14;100(1):170-177. Epub 2020 Sep 14.

Department of Obstetrics and Gynecology, The Chinese University of Hong Kong, Hong Kong, Hong Kong.

Introduction: Umbilical cord prolapse is a major obstetric emergency associated with significant perinatal complications. However, there is no consensus on the optimal decision-to-delivery interval, as many previous studies have shown poor correlation between the interval and umbilical cord arterial blood gas or perinatal outcomes. We aim to investigate whether bradycardia-to-delivery or decision-to-delivery interval was related to poor cord arterial pH or adverse perinatal outcome in umbilical cord prolapse. Read More

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January 2021

Fetomaternal Outcome of Pregnancy in Women with Tetralogy of Fallot.

Mymensingh Med J 2020 Jul;29(3):628-632

Dr Nargis Akhter, Associate Professor, Department of Gynae and Obstetrics, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh.

This prospective study was done to determine fetomaternal outcomes of pregnancy in women with Tetralogy of Fallot (TOF) and carried out in two centres especially in the care of patients with adult congenital heart disease (CHD) from January 2005 to December 2009. Clinical, haemodynamic and obstetric data were reviewed for pregnant women with TOF. Ten (10) pregnant women were identified in the age range 18 to 47 years. Read More

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Long-term effects of the nine-item list intervention on obstetric and neonatal outcomes in Robson group 1 - A time series study.

Acta Obstet Gynecol Scand 2021 01 1;100(1):154-161. Epub 2020 Sep 1.

Department of Obstetrics and Gynecology and Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.

Introduction: The nine-item list, with organizational and cultural changes, was implemented at the delivery unit in Linköping, Sweden between 2007 and 2010, aiming at improving the quality of care by offering more women a safe and attractive vaginal delivery. The target group for the intervention was nulliparous women at term with spontaneous onset of labor and cephalic presentation (Robson group 1). The aim of this study was to evaluate pregnancy outcomes before, during, early post and late post introduction of the nine-item list. Read More

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January 2021

Does the Caesarean Section Impact on 11β HSD2 and Fetal Cortisol?

Int J Environ Res Public Health 2020 08 1;17(15). Epub 2020 Aug 1.

First Department of Obstetrics and Gynaecology, Centre of Postgraduate Medical Education, Żelazna 90 Street, 01-004 Warsaw, Poland.

Purpose: Comparison of the activity of 11beta-hydroxysteroid dehydrogenase type 2 in the placenta and the umbilical cord blood cortisol level between caesarean sections with or without uterine contraction and vaginal delivery groups. Cortisol is the main stress hormone responsible for the normal adaptation of the neonate to extrauterine life. The disorders resulting from a dysfunction of the 11β-HSD 2-cortisol system can explain the higher risk of developing diseases in children born by caesarean section. Read More

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Clinical features and outcomes of pregnant women with COVID-19: a systematic review and meta-analysis.

BMC Infect Dis 2020 Aug 3;20(1):564. Epub 2020 Aug 3.

Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University) of Ministry of Education, Postal address: No. 20, Section 3, South Renmin Road, Cheng Du, Sichuan province, 610041, P. R. China.

Background: The recent COVID-19 outbreak in Wuhan, China, has quickly spread throughout the world. In this study, we systematically reviewed the clinical features and outcomes of pregnant women with COVID-19.

Methods: PubMed, Web of Science, EMBASE and MEDLINE were searched from January 1, 2020, to April 16, 2020. Read More

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Intestinal Dysbiosis As a Possible Predictor of Very Early Preterm Labor in Pregnant Women With Metabolic Syndrome.

J Med Life 2020 Apr-Jun;13(2):200-205

Lukianova Institute of Pediatrics, Obstetrics and Gynecology of the NAMS of Ukraine, Kyiv, Ukraine.

The work assessed the state of the intestinal microbiocenosis in 52 puerperae at the in whom the pregnancy developed against the background of the metabolic syndrome. The diagnosis of metabolic syndrome was determined according to the criteria approved by the World Health Organization for pregnant women. The state of intestinal microbiocenosis was assessed by a bacteriological examination of feces immediately after delivery. Read More

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September 2020

Neonatal outcome in 29 pregnant women with COVID-19: A retrospective study in Wuhan, China.

PLoS Med 2020 07 28;17(7):e1003195. Epub 2020 Jul 28.

International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Background: As of June 1, 2020, coronavirus disease 2019 (COVID-19) has caused more than 6,000,000 infected persons and 360,000 deaths globally. Previous studies revealed pregnant women with COVID-19 had similar clinical manifestations to nonpregnant women. However, little is known about the outcome of neonates born to infected women. Read More

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Shoulder Dystocia: Managing an Obstetric Emergency.

Am Fam Physician 2020 07;102(2):84-90

AdventHealth Orlando Family Medicine Residency Program, Orlando, FL, USA.

Shoulder dystocia is an obstetric emergency in which normal traction on the fetal head does not lead to delivery of the shoulders. This can cause neonatal brachial plexus injuries, hypoxia, and maternal trauma, including damage to the bladder, anal sphincter, and rectum, and postpartum hemorrhage. Although fetal macrosomia, prior shoulder dystocia, and preexisting or gestational diabetes mellitus increases the risk of shoulder dystocia, most cases occur without warning. Read More

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Induction of labor and nulliparity: A nationwide clinical practice pilot evaluation.

Acta Obstet Gynecol Scand 2020 12 27;99(12):1700-1709. Epub 2020 Jul 27.

Department of Obstetrics and Gynecology, Oslo University Hospital, Oslo, Norway.

Introduction: Induction of labor has become an increasingly common obstetric procedure, but in nulliparous women or women with a previous cesarean section, it can pose a clinical challenge. Despite an overall expansion of medical indications for labor induction, there is little international consensus regarding the criteria for induction, or for the recommended methods among nulliparous women. In this light, we assessed variations in the practice of induction of labor among 21 birth units in a nationwide cohort of women with no prior vaginal birth. Read More

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December 2020

Fetal goiter identified in a pregnant woman with triiodothyronine-predominant graves' disease: a case report.

BMC Pregnancy Childbirth 2020 Jun 3;20(1):344. Epub 2020 Jun 3.

Department of Obstetrics and Gynecology, Akita University Hospital, 1-1-1 Hondo, Akita, 010-8543, Japan.

Background: Approximately 10% of all Graves' disease cases are triiodothyronine (T3)-predominant. T3-predominance is characterized by higher T3 levels than thyroxine (T4) levels. Thyroid stimulating hormone receptor autoantibody (TRAb) levels are higher in T3-predominant Graves' disease cases than in non-T3-predominant Graves' disease cases. Read More

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