31,983 results match your criteria La Presse Medicale [Journal]


[Elimination of hepatitis C virus infection].

Authors:
Stanislas Pol

Presse Med 2019 Jan;48(1 Pt 1):1-3

Université Paris Sorbonne, France; Institut Pasteur, Unité des cellules dendritiques, Inserm U-1223, France; AP -HP, hôpital Cochin, département d'hépatologie, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.lpm.2019.01.001DOI Listing
January 2019

[Health students quality of life: A challenge for universities].

Presse Med 2019 Feb 14. Epub 2019 Feb 14.

Université de Tours, service de santé universitaire, 10, boulevard Tonnellé, 37000 Tours, France.

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http://dx.doi.org/10.1016/j.lpm.2019.01.003DOI Listing
February 2019

Intervention psychothérapeutique brève (activation comportementale) pour le traitement de la dépression d’intensité légère à modérée en soins primaires : proposition d’un guide pour la pratique clinique.

Presse Med 2019 Feb 12. Epub 2019 Feb 12.

CHRU de Tours, clinique psychiatrique universitaire, centre expert dépression résistante, FondaMental, 12-26, rue du Coq, 37540 Saint-Cyr-sur-Loire, France; UMR 1253, iBrain, INSERM, Université de Tours, 37000 Tours, France.

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http://dx.doi.org/10.1016/j.lpm.2018.09.016DOI Listing
February 2019

[Prevalence and risk markers of anxiety and depression among health students].

Presse Med 2019 Feb 12. Epub 2019 Feb 12.

CHRU de Tours, laboratoire de santé publique, 37000 Tours, France; Université de Tours, faculté de médecine, équipe « Éducation, éthique, santé » (EA 7505), 37000 Tours, France; Université de Tours, faculté de médecine, 37000 Tours, France.

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http://dx.doi.org/10.1016/j.lpm.2019.01.002DOI Listing
February 2019

[An high level diagnosis!]

Presse Med 2019 Feb 6. Epub 2019 Feb 6.

Hôpitaux universitaires de Strasbourg, hôpital de Hautepierre, service d'accueil des urgences, 1, avenue Molière, 67098 Strasbourg, France; Université de Strasbourg, UMR 1260, faculté de médecine, 4, rue Kirschleger, 67000 Strasbourg, France.

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http://dx.doi.org/10.1016/j.lpm.2018.11.018DOI Listing
February 2019

[Hypotensions in the elderly: Clinical and therapeutic features].

Presse Med 2019 Feb 3. Epub 2019 Feb 3.

Hôpitaux universitaires Pitié-Salpêtrière Charles-Foix, hôpital Charles-Foix, service de gériatrie, 94200 Ivry-sur-Seine, France; Université Sorbonne, faculté de médecine Sorbonne Médecine, 75013 Paris, France.

Hypotension and especially very low diastolic blood pressure could be an at-risk situation in very old and frail patients and in those with coronary heart disease. Chronic hypotension in people with heart failure is an indicator of poor prognosis and hinders the management of therapy. Orthostatic hypotension is a decrease in blood pressure>20mmHg for systolic and/or>10mmHg for diastolic within 3minutes after transition from supine to upright. Read More

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http://dx.doi.org/10.1016/j.lpm.2018.11.008DOI Listing
February 2019
1 Read

[Childhood trauma in subjects at ultra high risk for psychosis].

Presse Med 2019 Jan 30. Epub 2019 Jan 30.

Hôpital Razi, service de psychiatrie Ibn Omrane, 1, rue des orangers, 2010 La Manouba, Tunisie; Université Tunis El Manar, faculté de médecine de Tunis, , Tunisie.

Childhood adversity rates would be higher in subjects at ultra-high risk of psychosis than in the general population. In addition to reference ideas, magical thoughts and social dysfunction, subjects at ultra-high risk of psychosis with a history of childhood trauma would experience more severe and specific symptoms. Childhood trauma, especially sexual abuse, was associated with the transition to psychosis. Read More

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http://dx.doi.org/10.1016/j.lpm.2018.11.023DOI Listing
January 2019
1.173 Impact Factor

[Update of French guidelines for the use of positron emission tomography (PET) in gastro-intestinal cancer (Part of the InCa guidelines)].

Presse Med 2019 Jan 29. Epub 2019 Jan 29.

Hôpital Cochin, service de gastroentérologie et d'oncologie digestive, 75014 Paris, France.

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http://dx.doi.org/10.1016/j.lpm.2018.11.014DOI Listing
January 2019

Autoinflammatory diseases: State of the art.

Presse Med 2019 Feb 24;48(1 Pt 2):e25-e48. Epub 2019 Jan 24.

AP-HP, hôpital Tenon, Sorbonne université, service de médecine interne, centre de référence des maladies auto-inflammatoires et des amyloses d'origine inflammatoire (CEREMAIA), 75020 Paris, France; Assistance publique-Hôpitaux de Paris, hôpital Trousseau, université Pierre-et-Marie-Curie (UPMC)-Paris 6, Inserm UMRS_933, 75012 Paris, France.

Autoinflammatory diseases are characterized by innate immunity abnormalities. In autoinflammatory diseases (AID), inflammatory blood biomarkers are elevated during crisis without infection and usually without autoantibodies. The first 4 described AID were familial Mediterranean fever, cryopyrin-associated periodic fever syndrome (CAPS) or NLRP3-associated autoinflammatory disease (NRLP3-AID), mevalonate kinase deficiency (MKD) and TNFRSF1A-receptor associated periodic fever syndrome (TRAPS). Read More

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http://dx.doi.org/10.1016/j.lpm.2018.12.003DOI Listing
February 2019
1 Read

Familial Mediterranean Fever.

Presse Med 2019 Feb 25;48(1 Pt 2):e61-e76. Epub 2019 Jan 25.

University of Istanbul-Cerrahpasa, Cerrahpasa Medical Faculty, Division of Rheumatology, Department of Internal Medicine, 34098 Istanbul, Turkey.

Familial Mediterranean Fever (FMF) is the oldest and the most frequent of all described hereditary periodic fever syndromes. The populations originating from Mediterranean basin carry the highest risk for FMF however it is being increasingly recognized in many parts of the world. It is an autoinflammatory disease with an autosomal recessive transmission. Read More

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http://dx.doi.org/10.1016/j.lpm.2018.08.014DOI Listing
February 2019
1 Read

Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome - PFAPA syndrome.

Authors:
Per Wekell

Presse Med 2019 Feb 22;48(1 Pt 2):e77-e87. Epub 2019 Jan 22.

Department of Pediatrics, NU-Hospital Group, 45180 Uddevalla, Sweden; Department of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. Electronic address:

Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome is a complex autoinflammatory disease with a clinical phenotype characterised by recurrent episodes of fever, systemic inflammation and symptoms and signs depicted in disease acronym. Although PFAPA is the most common autoinflammatory disease among children in many parts of the world, the condition is still an enigma, which include the regular episodes, the prompt responses to corticosteroids, the genetic bases for the familial clustering and therapeutic effects of tonsillectomy. This review explores PFAPA syndrome with the aim of describing the current clinical and scientific understanding of the condition. Read More

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http://dx.doi.org/10.1016/j.lpm.2018.08.016DOI Listing
February 2019

[Prevalence of major depression in France in the general population and in specific populations from 2000 to 2018: A systematic review of the literature].

Presse Med 2019 Jan 21. Epub 2019 Jan 21.

Aix-Marseille université, faculté de médecine-Secteur Timone, EA 3279 : CEReSS-Centre d'étude et de recherche sur les services de santé et la qualité de vie, 27, boulevard Jean-Moulin, 13005 Marseille, France; Fondation FondaMental, 94000 Créteil, France.

Objective: To synthetize the data on the prevalence of major depressive disorders (MDD) in France in general population and in specific populations.

Method: A systematic review following the PRISMA criteria has been carried out. MEDLINE, google scholar, Isi web of science, PsychInfo et Cochrane library have been explored, from 2000 to April 2018. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07554982183048
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http://dx.doi.org/10.1016/j.lpm.2018.12.004DOI Listing
January 2019
8 Reads

Bilateral simultaneous central retinal vein occlusion revealing Waldenström's macroglobulinemia.

Presse Med 2019 Jan 18. Epub 2019 Jan 18.

University of Sfax, Habib Bourguiba University Hospital, Faculty of Medicine, Department of Ophthalmology, Sfax, Tunisia.

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http://dx.doi.org/10.1016/j.lpm.2018.11.004DOI Listing
January 2019

[Cutaneous abscesses with streptomyces rectiverticillatus during an interleukin 12 deficiency].

Presse Med 2019 Jan 18;48(1 Pt 1):85-87. Epub 2019 Jan 18.

Hôpital la Rabta, faculté de médecine de Tunis, service des maladies infectieuses, 1002 Tunis, Tunisie.

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http://dx.doi.org/10.1016/j.lpm.2018.09.017DOI Listing
January 2019
1 Read

[Neuro-lupus revealed by a hemiparesis and abnormal movements of a teenager].

Presse Med 2019 Jan 18. Epub 2019 Jan 18.

CHRU de Besançon, département de neurologie, 3, boulevard Alexandre-Fleming, 25000 Besançon, France.

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http://dx.doi.org/10.1016/j.lpm.2018.11.021DOI Listing
January 2019

[The impact of periodontal therapy on the diabetes control: A systematic review].

Presse Med 2019 Jan 18;48(1 Pt 1):4-18. Epub 2019 Jan 18.

Université Mohammed V, faculté de médecine dentaire, département de parodontologie, Rabat, Maroc; Université Mohammed V, faculté de médecine et de pharmacie, laboratoire de biostatistique de recherche clinique et d'épidémiologie, Rabat, Maroc.

Purpose: The bidirectional relationship between diabetes and periodontal disease has been established. Diabetes is a risk factor for periodontal disease while periodontal disease is a complication of diabetes. The objective of this systematic review is to determine whether the administration of periodontal therapy compared to the absence of this treatment would have an impact on the diabetes control in diabetic patients with periodontitis. Read More

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http://dx.doi.org/10.1016/j.lpm.2018.12.002DOI Listing
January 2019

[Aspirin and preeclampsia].

Presse Med 2019 Jan 18;48(1 Pt 1):34-45. Epub 2019 Jan 18.

Assistance publique-Hôpital de Paris, centre hospitalier universitaire Cochin Broca Hôtel-Dieu, groupe hospitalier universitaire Ouest, département de gynécologie-obstétrique, maternité de Port-Royal, 53, avenue de l'Observatoire, 75014 Paris, France; PRES Sorbonne Paris Cité, université Paris Descartes, Paris, France; Fondation PremUP, Paris, France; DHU Risques et grossesse, Paris, France.

Indications for aspirin during pregnancy are a matter of debate and there is a recent trend to an extended prescription and an overuse of aspirin in pregnancy. Aspirin is efficient in secondary prevention of preeclampsia essentially in patients with a personal history of preeclampsia. The effect of aspirin on platelet aggregation and on the TXA2/PGI2 balance is dose-dependent. Read More

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http://dx.doi.org/10.1016/j.lpm.2018.11.022DOI Listing
January 2019
10 Reads

[Ischemic stroke post varicella angiopathy in children].

Presse Med 2019 Jan 18. Epub 2019 Jan 18.

CHU Mohammed VI, service de pédiatrie, Oujda, Maroc.

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http://dx.doi.org/10.1016/j.lpm.2018.11.019DOI Listing
January 2019

[Hypertension in the elderly].

Presse Med 2019 Jan 18. Epub 2019 Jan 18.

Hôpital Broca, université Paris Descartes, gériatrie, 54-56, rue Pascal, 75013 Paris, France; AP-HP, hôpital Broca, EA 4468, 75013 Paris, France. Electronic address:

After 80 years old, antihypertensive treatment significantly reduces cardiovascular events. In the elderly, blood pressure target depends on patients' frailty. After 80 years, French guidelines propose to aim a SBP<150 mmHg without orthostatic hypotension and without exceeding the prescription of more than three antihypertensive drugs. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07554982183045
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http://dx.doi.org/10.1016/j.lpm.2018.11.011DOI Listing
January 2019
14 Reads

Autoinflammatory syndromes.

Presse Med 2019 Feb 19;48(1 Pt 2):e21-e23. Epub 2019 Jan 19.

AP-HP, hôpital Tenon, Sorbonne université, service de médecine interne, centre de référence des maladies auto-inflammatoires et des amyloses d'origine inflammatoire (CEREMAIA), 75020 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.lpm.2018.12.005DOI Listing
February 2019

[Asthma exacerbations in adults: Preventing and treat].

Presse Med 2019 Jan 18. Epub 2019 Jan 18.

Assistance publique-Hôpitaux de Paris, hôpital Bichat, centre de référence des maladies pulmonaires rares, service de pneumologie, département hospitalo-universitaire FIRE, 75877 Paris cedex 18, France; Université Paris Diderot, Inserm UMR 1152, 75018 Paris, France; LabEx Inflamex, 75018 Paris, France. Electronic address:

Exacerbations of asthma are still responsible for 900 deaths per year in France, most of which are considered preventable. They have a major impact on the quality of life of patients and are responsible for a large part of the socio-economic cost of asthma in France. Exacerbations of asthma can be partly prevented by inhaled corticosteroid treatment as controller therapy, at a dose adapted to the level of control of symptoms and the management of aggravating factors. Read More

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http://dx.doi.org/10.1016/j.lpm.2018.12.001DOI Listing
January 2019
1 Read

[About a lymphatic lumbago].

Presse Med 2019 Jan 18. Epub 2019 Jan 18.

Université Mohammed V, hôpital Avicenne, service de radiologie, Rabat, Maroc.

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http://dx.doi.org/10.1016/j.lpm.2018.11.020DOI Listing
January 2019

[Training to welcome families in intensive care unit by serious game].

Presse Med 2019 Jan 18. Epub 2019 Jan 18.

Hôpital Salengro, centre de réanimation, Entrée EST, rue P. Decoulx, 59037 Lille cedex, France.

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http://dx.doi.org/10.1016/j.lpm.2018.12.006DOI Listing
January 2019

How to prescribe a genetic test for the diagnosis of autoinflammatory diseases?

Presse Med 2019 Feb 18;48(1 Pt 2):e49-e59. Epub 2019 Jan 18.

University College London, National Amyloidosis Centre, Rowland Hill Street, London NW3 2PF, United Kingdom.

The systemic autoinflammatory disorders (SAIDs) are associated with dysregulation of the innate immune system, affecting pro-inflammatory cytokines and apoptosis pathways. The spectrum of SAIDs continues to grow with over 30 different disorders identified to date. The main indication for genetic referral is when a patient presents with clinical symptoms consistent with one or more of the SAIDs. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07554982183048
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http://dx.doi.org/10.1016/j.lpm.2018.08.015DOI Listing
February 2019
7 Reads

[Relapse of acute rheumatism fever associated with acute post-streptococcal glomerulonephritis].

Presse Med 2019 Jan 18. Epub 2019 Jan 18.

Centre hospitalier de Polynésie française, service de médecine interne et polyvalente, Tahiti, Polynésie française. Electronic address:

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http://dx.doi.org/10.1016/j.lpm.2018.11.024DOI Listing
January 2019
1 Read

[Essential hypertension: Definitions, hemodynamic, clinical and therapeutic review].

Presse Med 2019 Jan 18;48(1 Pt 1):19-28. Epub 2019 Jan 18.

AP-HP, université Paris-Descartes, hôpital hôtel-Dieu, centre de diagnostic et de thérapeutique, 1, place du Parvis de Notre-Dame, 75004 Paris, France. Electronic address:

Arterial hypertension is à chronic disease that affects more than 25 % of the French adult population. Increased peripheral resistance combined with normal cardiac output is a special feature of arterial hypertension. The increase in the resistance of arterioles remains an important feature of arterial hypertension while the study of the rigidity of large arterials trunks remains poorly explored. Read More

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http://dx.doi.org/10.1016/j.lpm.2018.11.017DOI Listing
January 2019

[Unusual mechanism of myocardial infarction in infective endocarditis].

Authors:
Yosra Messaoudi

Presse Med 2019 Jan 18;48(1 Pt 1):82-84. Epub 2019 Jan 18.

University of Sousse, faculty of medecine, Sousse, Tunisie; University of medecine, department of cardiology Ibn El Jazzar Hospital Kairouan, Sousse, Tunisie. Electronic address:

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http://dx.doi.org/10.1016/j.lpm.2018.04.012DOI Listing
January 2019
1 Read

[A splenic tendonitis ?]

Presse Med 2019 Jan 12;48(1 Pt 1):91-94. Epub 2018 Dec 12.

Hôpital Ibn Sina, service d'anatomie pathologique, Rabat, Maroc.

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http://dx.doi.org/10.1016/j.lpm.2018.11.013DOI Listing
January 2019

[Surgical repair of the sequelae of simultaneous burns of the four eyelids].

Presse Med 2019 Jan 11;48(1 Pt 1):89-90. Epub 2018 Dec 11.

Hôpital Habib Bourguiba de Sfax, service de chirurgie plastique réparatrice et esthétique, rue Al Firdaws, Sfax Tunisie.

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http://dx.doi.org/10.1016/j.lpm.2018.03.026DOI Listing
January 2019

Cutaneous vasculitis preceding the onset of anti-GBM disease (Goodpasture syndrome).

Authors:
Nicolas Kluger

Presse Med 2019 Jan 10;48(1 Pt 1):79-80. Epub 2018 Dec 10.

University of Helsinki, Helsinki University Central Hospital, Departments of dermatology, allergology and venereology, Meilahdentie 2, PO Box 160, 00029 Helsinki, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.lpm.2018.11.001DOI Listing
January 2019

[Retroperitoneal leiomyosarcoma in adult].

Presse Med 2019 Jan 10;48(1 Pt 1):77-79. Epub 2018 Dec 10.

Hôpital Militaire de Tunis, service d'oncologie médicale, Tunisie.

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http://dx.doi.org/10.1016/j.lpm.2018.11.003DOI Listing
January 2019

[Aortic stenosis in the elderly: The TAVI revolution].

Presse Med 2018 Dec 10. Epub 2018 Dec 10.

Hôpital Pitié-Salpêtrière (AP-HP), ACTION Study Group, Sorbonne Université, Université Paris 06 (UPMC), Inserm UMRS 1166, institut de cardiologie, Paris, France. Electronic address:

TAVI is currently recommended for severe symptomatic aortic stenosis in patients at prohibitive, high or intermediate surgical risk as estimated by surgical risk scores (STS score and EuroSCORE II). Comorbidity, technical feasibility of TAVI and concurrent pathology with need for complementary surgical correction are conditions to be considered to choose between open surgery and TAVI. The decision is often made by the "Heart Team". Read More

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http://dx.doi.org/10.1016/j.lpm.2018.11.007DOI Listing
December 2018

Dubin-Johnson syndrome in Tunisia: Spectrum of a rare disease.

Presse Med 2019 Jan 10;48(1 Pt 1):81-82. Epub 2018 Dec 10.

Laboratory of Experimental Hepatology, Experimental Medicine Centre, Institute for Clinical and Experimental Medicine, 14021 Prague 4, Czech Republic.

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http://dx.doi.org/10.1016/j.lpm.2018.09.020DOI Listing
January 2019
1 Read

[Alpha chain disease: From bedside to bench and back again, an exemplary translation].

Presse Med 2019 Jan 7;48(1 Pt 1):63-67. Epub 2018 Dec 7.

Université Paris-Diderot, faculté de médecine, 75010 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.lpm.2018.06.017DOI Listing
January 2019
3 Reads

Piezogenic pedal papules.

Presse Med 2019 Jan 7;48(1 Pt 1):88. Epub 2018 Dec 7.

University Hospital of Geneva, department of Dermatology, Geneva, Switzerland.

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https://linkinghub.elsevier.com/retrieve/pii/S07554982183037
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http://dx.doi.org/10.1016/j.lpm.2018.09.018DOI Listing
January 2019
5 Reads

High-degree atrioventricular block revealing hypertrophic cardiomyopathy related to a mutation in MYBPC3 gene.

Presse Med 2019 Jan 7;48(1 Pt 1):68-71. Epub 2018 Dec 7.

Lille University Hospital, Department of Cardiology, 59037 Lille cedex, France.

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http://dx.doi.org/10.1016/j.lpm.2018.11.012DOI Listing
January 2019
1 Read

Tattooing and multiple sclerosis: A study among 445 French patients.

Authors:
Nicolas Kluger

Presse Med 2018 Dec 7. Epub 2018 Dec 7.

University of Helsinki and Helsinki University Central Hospital, Department of Dermatology, Allergology and Venereology, Helsinki, Finland; Assistance publique-Hôpitaux de Paris, Bichat-Claude Bernard Hospital, "Tattoo" consultation, Department of dermatology, 75018 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.lpm.2018.11.002DOI Listing
December 2018

Health care services and disease modifying therapies use in community-based multiple sclerosis patients: Evolution from 2013 to 2015 and demographic characteristics.

Presse Med 2019 Jan 7;48(1 Pt 1):e1-e19. Epub 2018 Dec 7.

Agence Régionale de Santé ARS, 13002 Marseille, France.

Interest Of The Work: Multiple sclerosis (MS) disease modifying therapies (DMT) utilization increased during the last decade with the approval of new drugs. Symptomatic treatments also play an important role. Describing time trends and demographic characteristics for DMT and symptomatic treatments utilization in population-based MS patients will lead to a better knowledge of the resources distribution. Read More

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http://dx.doi.org/10.1016/j.lpm.2018.04.013DOI Listing
January 2019

[Treatment with oral anticoagulants in older patients: Should warfarin still be prescribed?]

Presse Med 2018 Dec 7. Epub 2018 Dec 7.

AP-HP, hôpitaux universitaires Pitié-Salpêtrière-Charles Foix, site Charles Foix, service de gériatrie à orientation cardiologique et neurologique, 94205 Ivry-sur-Seine, France; Sorbonne université, faculté de médecine, 75013 Paris, France.

Vitamin-K antagonists (VKA) have been the standard for oral anticoagulation. However, they carry several problems in older patients: frequent bleeding complications, complex management, risk of interactions with multiple drugs. Two classes of direct oral anticoagulants (DOA) are currently available in France: (a) direct thrombin inhibitors: dabigatran; and (b) direct factor Xa inhibitors: rivaroxaban, apixaban and others. Read More

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http://dx.doi.org/10.1016/j.lpm.2018.11.010DOI Listing
December 2018
1 Read

[Dramatic improvement after decompressive craniectomy in a fulminant stroke-like case of herpes simplex encephalitis].

Presse Med 2019 Jan 7;48(1 Pt 1):74-77. Epub 2018 Dec 7.

Hôpital d'instruction des armées Sainte-Anne, service de neurochirurgie, BP600, 83800 Toulon Cedex 09, France.

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http://dx.doi.org/10.1016/j.lpm.2018.11.005DOI Listing
January 2019
1 Read

LPAC syndrome: An uncommon etiology of intrahepatic cholelithiasis.

Presse Med 2019 Jan 7;48(1 Pt 1):72-74. Epub 2018 Dec 7.

Mohamed Taher Maamouri Hospital, Gastro enterology department, Nabeul, Tunisia.

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http://dx.doi.org/10.1016/j.lpm.2018.11.006DOI Listing
January 2019
1 Read

[Biological function and dysfunction today: From the perspective of Georges Canguilhem].

Presse Med 2018 Dec 7. Epub 2018 Dec 7.

Université Paris I, Panthéon Sorbonne, 17, rue de la Sorbonne, 75005 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.lpm.2018.07.009DOI Listing
December 2018

[Treatment de-escalation in inflammatory bowel diseases].

Authors:
Vered Abitbol

Presse Med 2018 Nov - Dec;47(11-12 Pt 1):931-933

Hôpital Cochin, service de gastroentérologie, 27, rue du Faubourg-Saint-Jacques, 75014 Paris, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07554982183046
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http://dx.doi.org/10.1016/j.lpm.2018.11.015DOI Listing
December 2018
1 Read

Neuro-oncology: A rapidly evolving multidisciplinary speciality.

Presse Med 2018 Nov - Dec;47(11-12 Pt 2):e185-e186

Sorbonne université, Inserm, CNRS, UMR S 1127, institut du cerveau et de la moelle épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié-Salpêtrière-Charles-Foix, service de neurologie 2-Mazarin, 75013 Paris, France.

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http://dx.doi.org/10.1016/j.lpm.2018.11.016DOI Listing
December 2018
1 Read

[Benzodiazepine cessation in ambulatory practice. A review].

Presse Med 2018 Oct 24;47(10):899-912. Epub 2018 Oct 24.

AP-HP, hôpital Fernand-Widal, département de psychiatrie et de médecine addictologique, 200, rue du Faubourg-Saint-Denis, 75010 Paris, France; Faculté de médecine Paris-Diderot et Inserm Umrs 1144, 75006 Paris, France. Electronic address:

Seven studies evaluated pharmacological treatments and 12 studies evaluated non-pharmacological interventions including Cognitive Behavioural Therapy (CBT), minimal interventions toward patients, pharmacists or physicians, or dedicated visits, in order to discontinue benzodiazepines treatments. Among pharmacological treatments, only melatonin was significantly efficacious in patients suffering from insomnia alone. BCT showed efficacy in increasing self-efficacy feeling toward BZD cessation and in patients with sleep disorders. Read More

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http://dx.doi.org/10.1016/j.lpm.2018.10.007DOI Listing
October 2018
17 Reads

[Should the duration of treatment be limited using benzodiazepines?]

Presse Med 2018 Oct 25;47(10):892-898. Epub 2018 Oct 25.

Université Bordeaux, Inserm, Bordeaux Population Health Research Center, Pharmaco epidemiology research team, UMR 1219, 33000 Bordeaux, France; Centre hospitalier Charles-Perrens, 33000 Bordeaux, France. Electronic address:

Benzodiazepines and Z-drugs have pharmacodynamic effects with tolerance that can occur quickly, after one week to one month of treatment and that concerns hypnotic and anxiolytic properties in particular. Old studies showed a real but poor short-term efficacy of benzodiazepines on anxiety and sleep disturbances. Long-term efficacy of benzodiazepines can be confused with the occurrence of rebound effect, discontinuation symptoms or relapse when the treatment is quitted; they contribute to an apparent efficacy, as well as the symptoms removal when treatment is re-initiated. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07554982183038
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http://dx.doi.org/10.1016/j.lpm.2018.10.006DOI Listing
October 2018
9 Reads

[Use and misuse of benzodiazepines out of France].

Presse Med 2018 Oct 25;47(10):882-885. Epub 2018 Oct 25.

Université Bordeaux, Inserm, Bordeaux Population Health Research Center, Pharmacoepidemiology research team, UMR 1219, 33000 Bordeaux, France; DRUGS-SAFE National Platform of Pharmacoepidemiology, France.

Among 8 countries included in the report of ANSM, France is second behind Spain, when defined daily doses (DDD) are considered. Few studies, recent and based on representative samples of population, investigated the use of benzodiazepines in other countries and data are limited to compare France and other countries. In most countries, the use of benzodiazepines increases with age and is more frequent in women than in men. Read More

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http://dx.doi.org/10.1016/j.lpm.2018.10.004DOI Listing
October 2018
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[Benzodiazepine use and misuse in France].

Presse Med 2018 Oct 25;47(10):878-881. Epub 2018 Oct 25.

University of Bordeaux, Inserm, Bordeaux Population Health Research Center, team Pharmacoepidemiology, UMR 1219, 33076 Bordeaux, France; DRUGS-SAFE National Platform of Pharmacoepidemiology, 33076 Bordeaux, France; University Hospital of Bordeaux, Clinical Pharmacology, 33076 Bordeaux, France.

Benzodiazepine use remains high in France in 2015, especially among the elders. However, encouraging trend is observed regarding hypnotic benzodiazepines initiation: between 2008 and 2015, incident use of hypnotics, including that of Z-drugs, decreased while incident use of anxiolytics remained stable. Most of new benzodiazepine users (86 %) had treatment duration that complies with guidelines. Read More

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http://dx.doi.org/10.1016/j.lpm.2018.10.005DOI Listing
October 2018
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