8,882 results match your criteria LP Lumbar Puncture


Shunt tapping versus lumbar puncture for evaluating cerebrospinal fluid infections in pediatric population.

Turk Neurosurg 2018 Oct 2. Epub 2018 Oct 2.

Antalya Education and Research Hospital.

Aim: There is no consensus in the literature regarding the optimal method of obtaining cerebrospinal fluid sample in patients with suspected shunt infections. The most frequently used method is tapping shunt reservoir. Lumbar puncture is an alternative method yet it used far less frequently. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5137/1019-5149.JTN.24714-18.1DOI Listing
October 2018

Sphenopalatine ganglion block for treatment of post-dural puncture headache in obstetric patients: An observational study.

Indian J Anaesth 2018 Dec;62(12):972-977

Department of Anaesthesiology and Critical Care, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.

Background And Aims: Post-dural puncture headache (PDPH) is a consequence of spinal and epidural anaesthesia in approximately 1% of obstetric patients. The gold standard for its treatment is epidural blood patch. Sphenopalatine ganglion block (SPGB) has been proposed as a non-invasive intervention with minimal adverse effect. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/ija.IJA_443_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299770PMC
December 2018

Minimally invasive spinal anesthesia for cesarean section in maternal anticoagulation therapy: a randomized controlled trial.

BMC Anesthesiol 2019 Jan 12;19(1):11. Epub 2019 Jan 12.

Department of Anesthesiology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200127, China.

Background: Anticoagulant therapy during pregnancy is widely used due to the increasing awareness of maternal hypercoagulability. Few studies have reported the use of minimally invasive spinal anesthesia in these parturients. The objective of this study was to evaluate the safety and feasibility of minimally invasive spinal anesthesia in parturients with anticoagulation therapy undergoing cesarean section. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12871-018-0679-1DOI Listing
January 2019

Can an inflammatory reaction in the meninges, caused by spinal puncture through tattooed skin, evolve into adhesive arachnoiditis? An experimental model in rabbits.

Reg Anesth Pain Med 2019 Jan 11. Epub 2019 Jan 11.

Department of Anesthesiology, Botucatu Medical School, University of São Paulo State, UNESP, São Paulo, Brazil.

Background And Objectives: As the number of people with tattoos has been increasing, anesthesiologists are more and more faced with the decision to perform a neuraxial blockage through tattooed skin. In this study, we evaluated the possibility of puncture through tattooed skin determines acute inflammatory changes in the meninges and spinal cord and later evolve into adhesive arachnoiditis.

Method: Forty-two male rabbits were randomized into 3 groups of 14: G1, spinal puncture through non-tattooed skin and saline solution injection; G2, spinal puncture through tattooed skin and saline solution injection, captive for 30 days; G3, spinal puncture through tattooed skin and saline solution injection, captive for 360 days. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/rapm-2018-100085DOI Listing
January 2019
1 Read

Postdural puncture headache: Incidence and predisposing factors in a university hospital.

Agri 2019 Jan;31(1):1-8

Division of Algology, Department of Anesthesiology and Reanimation, Gaziantep University Faculty of Medicine, Gaziantep, Turkey.

Objectives: Postdural puncture headache (PDPH) may occur 12-72 hours after spinal anesthesia. PDPH causes patient discomfort following spinal anesthesia and therefore it presents a challenging situation for anesthetists.

Methods: This prospective randomized study enrolled 613 patients who were 18 years or older and who had been operated under spinal anesthesia. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5505/agri.2018.43925DOI Listing
January 2019

[Transient unilateral sudden hearing loss after spinal anesthesia].

Agri 2019 Jan;31(1):50-52

Department of Anesthesiology and Reanimation, Ordu State Hospital, Ordu,Turkey.

Hearing loss after spinal anesthesia is one of the rare complications. It has been suggested that low frequent hearing loss develops after the development of endolymphatic hydrops in the cochlea due to CSF escape after dural puncture. Hearing loss after nonotologic surgical procedures is very rare and usually can only be determined by audiometric evaluation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5505/agri.2017.17136DOI Listing
January 2019

Post dural puncture headache: a review of the literature.

Minerva Anestesiol 2019 Jan 4. Epub 2019 Jan 4.

Department of Anaesthesiology, University Hospital Basel, Basel, Switzerland.

Neuraxial analgesia and anaesthesia are widely used in obstetric anaesthesia. The most frequent complication after neuraxial blocks is post dural puncture headache. It can occur after unintentional dural puncture during epidural procedures or after spinal anaesthesia. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.23736/S0375-9393.18.13331-1DOI Listing
January 2019

Cerebrospinal Fluid Pressure-Related Features in Chronic Headache: A Prospective Study and Potential Diagnostic Implications.

Front Neurol 2018 18;9:1090. Epub 2018 Dec 18.

Neurosciences Research Center, Magna Græcia University, Catanzaro, Italy.

To identify the pressure-related features of isolated cerebrospinal fluid hypertension (ICH) in order to differentiate headache sufferers with ICH from those with primary headache disorder. In this prospective study, patients with refractory chronic headaches and suspected of having cerebrospinal fluid-pressure elevation without papilledema or sixth nerve palsy, together with controls, underwent 1-h lumbar cerebrospinal fluid pressure monitoring via a spinal puncture needle. We recruited 148 consecutive headache patients and 16 controls. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fneur.2018.01090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305580PMC
December 2018

Reversible intracranial hypertension following treatment of an extracranial vascular malformation: case report.

J Neurosurg Pediatr 2019 Jan 4:1-5. Epub 2019 Jan 4.

3Neurointerventional Radiology, Boston Children's Hospital, Boston, Massachusetts.

Pediatric hydrocephalus is a well-studied and still incompletely understood entity. One of the physiological means by which hydrocephalus and intracranial hypertension evolve is through perturbations to normal vascular dynamics. Here the authors report a unique case of an extracranial vascular anomaly resulting in persistently elevated intracranial pressures (ICPs) independent of CSF diversion in a patient with a Joubert syndrome-related disorder. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3171/2018.10.PEDS18235DOI Listing
January 2019

Bleeding complications following peripheral regional anaesthesia in patients treated with anticoagulants or antiplatelet agents: a systematic review.

Anaesth Crit Care Pain Med 2018 Dec 23. Epub 2018 Dec 23.

Department of anaesthesiology and intensive care, Grenoble Alpes University Hospital, France. Electronic address:

Background: Patients on either antiplatelet or anticoagulant therapy may need procedures performed under peripheral nerve blocks in preference to general anaesthesia techniques. The risk of bleeding associated with peripheral nerve blocks under these circumstances remains unknown. This systematic review evaluates the incidence of bleeding complications following peripheral nerve blocks in patients receiving antiplatelet and/or anticoagulant medication. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.accpm.2018.12.009DOI Listing
December 2018
1 Read

Optical coherence tomography represents a sensitive and reliable tool for routine monitoring idiopathic intracranial hypertension with and without papilledema.

Eur J Neurol 2018 Dec 26. Epub 2018 Dec 26.

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada.

Background: We previously reported that certain optical coherence tomography (OCT) measures were sensitive and reliable in identifying idiopathic intracranial hypertension (IIH). This prospective study aims to define OCT measures which allow differentiation of IIH with and without papilledema, thereby helping clinical decision-making.

Materials And Methods: 8 IIH patients with papilledema, 9 without papilledema and 19 with other neurological diseases (OND) were included. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ene.13893DOI Listing
December 2018

[Post-lumbar puncture syndrome].

Zh Nevrol Psikhiatr Im S S Korsakova 2018 ;118(11):87-92

Emergency Headache Center, Lariboisiere Hospital, AP-HP, F-75010, Paris, France.

This article presents a clinical case which describes some clinical aspects, risk factors, management and the prophylactic methods to prevent the post-lumbar puncture syndrome. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17116/jnevro201811811187DOI Listing
January 2018

Ultrasound Guided Lumbar Puncture and Remote Guidance for Potential In-Flight Evaluation of VIIP/SANS.

Aerosp Med Hum Perform 2019 Jan;90(1):58-62

Changes of visual function/neuro-opthalmic structures during spaceflight have been described as visual impairment and intracranial pressure syndrome (VIIP)/spaceflight-associated neuro-ocular syndrome (SANS). Although theories are suggested, the mechanism is unknown. Only indirect measurements of intracranial pressure (ICP) have been performed in spaceflight. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3357/AMHP.5170.2019DOI Listing
January 2019

The link between idiopathic intracranial hypertension, fibromyalgia, and chronic fatigue syndrome: exploration of a shared pathophysiology.

J Pain Res 2018 10;11:3129-3140. Epub 2018 Dec 10.

Department of Rehabilitation Sciences, Faculty of Kinesiology and Rehabilitation Sciences, Musculoskeletal Rehabilitation Research Unit, University of Leuven, Leuven, Belgium,

Purpose: Idiopathic intracranial hypertension (IICH) is a condition characterized by raised intracranial pressure (ICP), and its diagnosis is established when the opening pressure measured during a lumbar puncture is elevated >20 cm HO in nonobese patients or >25 cm HO in obese patients. Papilledema is caused by forced filling of the optic nerve sheath with cerebrospinal fluid (CSF). Other common but underappreciated symptoms of IICH are neck pain, back pain, and radicular pain in the arms and legs resulting from associated increased spinal pressure and forced filling of the spinal nerves with CSF. Read More

View Article

Download full-text PDF

Source
https://www.dovepress.com/the-link-between-idiopathic-intrac
Publisher Site
http://dx.doi.org/10.2147/JPR.S186878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292399PMC
December 2018
6 Reads

Management of non-missile penetrating spinal injury.

Neurosurg Rev 2018 Dec 18. Epub 2018 Dec 18.

Department of Neurosurgery, University of Utah School of Medicine, Salt Lake City, UT, USA.

Review of the literature with case illustration. Non-missile penetrating spinal injury (NPSI) represents a small subset of spinal cord injuries at tertiary trauma centers and is comprised mostly of knife violence. Strict guidelines for the management of penetrating spinal cord injury remain elusive given the variability of mechanisms, rarity of clinical experience, and paucity of prospective studies. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10143-018-01057-1DOI Listing
December 2018
1 Read

[Subjective memory impairments in early detection of dementia: Relation to acceptability of lumbar puncture in memory clinic patients].

Fortschr Neurol Psychiatr 2018 Dec 17. Epub 2018 Dec 17.

Vitos Klinikum Gießen-Marburg, Vitos Klinik für Psychiatrie und Psychotherapie Gießen; Fachbereich Medizin, Philipps-Universität Marburg.

Background: In memory clinics, biomarker-based diagnostic tools for early detection and differential diagnosis of dementia are increasingly important, even if their acceptance by patients is relatively low.

Objective: The aim of study was to examine whether sociodemographic and clinical features of memory clinic patients are associated with acceptance of lumbar puncture (LP). Of particular interest was the patients' self-perception of memory decline (subjective memory impairment, SMI) accompanied by related concerns that might affect decision to consent to LP. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/a-0644-2530DOI Listing
December 2018
1 Read

Epidemiology of lumbar punctures in hospitalized patients in the United States.

PLoS One 2018 13;13(12):e0208622. Epub 2018 Dec 13.

Department of Emergency Medicine, University of Alabama School of Medicine, Birmingham, Alabama, United States of America.

Objectives: Lumbar puncture (LP) is an important technique for assessing and treating neurological symptoms. The objective of this study was to describe the characteristics of diagnostic lumbar punctures performed on hospitalized patients in the United States.

Methods: We analyzed data from the 2010 National Inpatient Sample (NIS) and the National Emergency Department Survey (NEDS). Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0208622PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292631PMC
December 2018
2 Reads
3.234 Impact Factor

The Comparative Treatment of Intraventricular Chemotherapy by Ommaya Reservoir vs. Lumbar Puncture in Patients With Leptomeningeal Carcinomatosis.

Front Oncol 2018 20;8:509. Epub 2018 Nov 20.

Emergency Department, National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez" (INNN), Mexico City, Mexico.

Leptomeningeal Carcinomatosis (LCM) represents a state of systemic malignant disease with poor prognosis. The purpose of this study is to compare overall survival (OS) between intraventricular chemotherapy through Ommaya reservoir (OR) and chemotherapy through lumbar puncture (LP) in LCM. Forty adult patients with LCM were included. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fonc.2018.00509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256195PMC
November 2018
1 Read

Broken needle during spinal anesthesia: an avoidable complication.

Local Reg Anesth 2018 23;11:111-113. Epub 2018 Nov 23.

Department of Anesthesia, Ales-en-Cévennes Hospital, Alès-en-Cévennes, France.

The occurrence of a needle breaking is a very rare complication of spinal anesthesia (SA). We report a case of a broken spinal needle occurring in a morbid obese pregnant woman during SA indicated for an emergent cesarean section. Multiple puncture attempts due to difficult identification of lumbar spine, associated with an inadequate use of the introducer, contributed to this complication. Read More

View Article

Download full-text PDF

Source
https://www.dovepress.com/broken-needle-during-spinal-anesth
Publisher Site
http://dx.doi.org/10.2147/LRA.S175547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260186PMC
November 2018
5 Reads

Incidence and management of post-dural puncture headache following spinal anaesthesia and accidental dural puncture from a non-obstetric hospital: A retrospective analysis.

Indian J Anaesth 2018 Nov;62(11):881-886

Department of Anaesthesia, Critical Care and Pain, Tata Memorial Hospital and Homi Bhabha National Institute, Mumbai, Maharashtra, India.

Background And Aims: Post-dural puncture headache (PDPH) is one of the complications following spinal anaesthesia (SA) and accidental dural puncture (ADP). In our institute, we routinely practice epidural analgesia (EA) for supra-major surgeries. Our previous audit on EA revealed 4% incidence of ADP. Read More

View Article

Download full-text PDF

Source
http://www.ijaweb.org/text.asp?2018/62/11/881/244837
Publisher Site
http://dx.doi.org/10.4103/ija.IJA_354_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236776PMC
November 2018
6 Reads

[Perineural cysts].

Pol Merkur Lekarski 2018 Nov;45(269):201-204

St Johns' Cancer Center in Lublin; Department of Human Anatomy, Medical University of Lublin.

Perineural cyst (Tarlov cyst) is a lesion in a form of fluid-filled sacks, usually located within the nerve root sheath at the posterior root of a spinal nerve, whose wall is formed by: endoneurium, peripheral nerve fibers and ganglion cells and areolar tissue. Depending on the studied population, the frequency of lesion occurence was estimated at 1.5- 13. Read More

View Article

Download full-text PDF

Source
November 2018

Effects of low-intensity electrical stimulation and adipose derived stem cells transplantation on the time-domain analysis-based electromyographic signals in dogs with SCI.

Neurosci Lett 2018 Dec 4;696:38-45. Epub 2018 Dec 4.

Institute of Technical Sciences of the Serbian Academy of Sciences and Arts, Belgrade, Serbia.

Introduction: The application of low-intensity electrical stimulation (LIES) to neural tissue increases neurochemical factors responsible for regeneration as nerve growth factor. Stem cell (SC) therapy for patients with Spinal cord injury (SCI) promote some increase functional improvement.

Objective: Investigate the electromyographic response in paraplegic dogs undergoing LIES and SC transplantation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neulet.2018.12.004DOI Listing
December 2018

[Percutaneous transforaminal endoscopic TESSYS technique for the treatment of bilateral lumbar disc herniation in single segment].

Zhongguo Gu Shang 2018 Nov;31(11):1041-1045

Spinal Minimally Invasive Department, Xi'an Honghui Hospital Xi'an 710054, Shaanxi, China;

Objective: To investigate the early clinical effects of transforaminal endoscopic spine system (TESSYS) for the treatment of bilateral lumbar disc herniation in single segment.

Methods: The clinical data of 38 patients with single-segment bilateral lumbar disc herniation treated by TESSYS technique from February 2016 to February 2018 were retrospectively analyzed. There were 26 males and 12 females, aged from 30 to 55 years old with an average of(35. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3969/j.issn.1003-0034.2018.11.011DOI Listing
November 2018
1 Read

A 10-year update: national survey questionnaire of obstetric anesthesia units in Israel.

Int J Obstet Anesth 2018 Nov 2. Epub 2018 Nov 2.

Department of Anesthesiology, Perioperative Medicine & Pain Treatment, Shaare Zedek Medical Center, Affiliated with the Hadassah-Hebrew University Medical School Ein-Kerem, Jerusalem, Israel.

Background: This nationwide survey was conducted to provide data about the obstetric anesthesia services in Israeli labor and delivery units in 2016.

Methods: Prospective survey questionnaire was emailed to obstetric anesthesia unit directors/chairperson of all 25 labor and delivery services units within the jurisdiction of the Israeli Ministry of Health.

Results: The response rate was 100%. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijoa.2018.10.014DOI Listing
November 2018
1 Read

C-Reactive Protein (CRP) levels in neonatal meningitis in England: an analysis of national variations in CRP cut-offs for lumbar puncture.

BMC Pediatr 2018 Dec 3;18(1):380. Epub 2018 Dec 3.

Department of Paediatrics, Kingston Hospital, Kingston, London, KT2 7QB, UK.

Background: Recent National Institute for Health and Care Excellence (NICE) CG149 guidelines suggest considering performing a lumbar puncture (LP) to investigate for meningitis in early-onset sepsis in a neonate when a C-reactive protein (CRP) level >10mg/L, but the evidence for this recommendation is poorly defined.

Methods: Data on trust-wide LP protocols, neonatal meningitis incidence, lumbar punctures, and CRP levels seen in cases of neonatal meningitis were asked of all 137 trusts in England that recorded a birth in 2017. Our local Kingston Hospital data on every LP performed was obtained to estimate the specificity of CRP rises. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12887-018-1354-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276241PMC
December 2018
2 Reads

Development and validation of a predictive risk factor model for epidural re-siting in women undergoing labour epidural analgesia: a retrospective cohort study.

BMC Anesthesiol 2018 Nov 29;18(1):176. Epub 2018 Nov 29.

Department of Women's Anaesthesia, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore, 229899, Singapore.

Background: Epidural catheter re-siting in parturients receiving labour epidural analgesia is distressing to the parturient and places them at increased complications from a repeat procedure. The aim of this study was to develop and validate a clinical risk factor model to predict the incidence of epidural catheter re-siting in labour analgesia.

Methods: The data from parturients that received labour epidural analgesia in our centre during 2014-2015 was used to develop a predictive model for epidural catheter re-siting during labour analgesia. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12871-018-0638-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267799PMC
November 2018
1 Read

Increased Intracranial Pressure in Acute Disseminated Encephalomyelitis.

J Child Neurol 2018 Nov 27:883073818811541. Epub 2018 Nov 27.

2 Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Tel Aviv, Israel.

Objective:: To assess the intracranial pressure in pediatric acute disseminated encephalomyelitis using spinal tap opening pressure on lumbar puncture, which is routinely performed as part of suspected acute disseminated encephalomyelitis workup. Compared to other cerebrospinal fluid parameters such as cell count, protein concentration, and presence of oligoclonal bands, cerebrospinal fluid opening pressure is infrequently recorded.

Methods:: A retrospective chart review of demographic, clinical, and laboratory data of children diagnosed with acute disseminated encephalomyelitis admitted to a tertiary referral hospital between 2005 and 2016. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0883073818811541DOI Listing
November 2018
7 Reads

Are Incoming Pediatric Interns Ready to Obtain the Essential Components of an Informed Consent for Lumbar Puncture?

Acad Pediatr 2018 Nov 23. Epub 2018 Nov 23.

Department of Pediatrics (EA Omoruyi, A Guardiola, and MS Barratt), McGovern Medical School, The University of Texas Health Science Center, Houston, Tex.

Objective: In 2013, the Association of American Medical Colleges created the "Core Entrustable Professional Activities (EPAs) for Entering Residency" to more clearly define the set of activities that entering residents should be able to perform on day 1 of residency without direct supervision. EPA #11 is obtaining informed consent for tests and/or procedures. This EPA acknowledges that an entrustable learner should be able to document a complete consent among other components. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.acap.2018.11.011DOI Listing
November 2018
1 Read

Biochemical Differences Between Vitreous Humor and Cerebral Spinal Fluid in a Death From Diabetic Ketoacidosis.

Am J Forensic Med Pathol 2018 Nov 20. Epub 2018 Nov 20.

Forensic Pathology and.

Biochemical analysis of cerebrospinal fluid (CSF) and vitreous humor (VH) forms an important diagnostic ancillary test at autopsy. Cerebrospinal fluid can be sampled from the ventricular system (VA) and from lumbar puncture (LP), whereas VH can be sampled from the orbits. Biochemical electrolytes seem to vary between VH and CSF collected from different sites, but whether there is any difference in glucose and β-hydroxybutyrate is unclear. Read More

View Article

Download full-text PDF

Source
http://Insights.ovid.com/crossref?an=00000433-900000000-9917
Publisher Site
http://dx.doi.org/10.1097/PAF.0000000000000450DOI Listing
November 2018
4 Reads

Is there a role for lumbar puncture in early detection of subarachnoid hemorrhage after negative head CT?

Intern Emerg Med 2018 Nov 24. Epub 2018 Nov 24.

Emergency Department, Turku University Hospital, Turku, Finland.

To investigate the role of lumbar puncture (LP) after a negative head computed tomography (CT) when ruling out subarachnoid hemorrhage (SAH) within 24 h of symptom onset. In a single-center, retrospective cohort study, we studied a consecutive series of patients from 2011 to 2015. All patients underwent CT or CT following LP to rule out SAH. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11739-018-1982-zDOI Listing
November 2018
1 Read

Intrathecal administration of nusinersen in adolescent and adult SMA type 2 and 3 patients.

J Neurol 2018 Nov 20. Epub 2018 Nov 20.

Department of Orthopedic Surgery, RKU-University and Rehabilitation Clinics, Ulm University, Ulm, Germany.

Spinal muscular atrophy is a genetic motor neuron disease that leads to progressive muscular atrophy and muscle weakness. In December 2016, the Food and Drug Administration, and in June 2017, the European Medicines Agency approved the antisense oligonucleotide nusinersen for treatment of spinal muscular atrophy. Nusinersen has to be repeatedly administered intrathecally. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00415-018-9124-0DOI Listing
November 2018
11 Reads

Management of Chyloretroperitoneum After Lumbar Surgery by Anterior Approach.

World Neurosurg 2018 Nov 14. Epub 2018 Nov 14.

Department of Neurosurgery, Sainte Anne Military Hospital, Toulon, France; French Military Health Service Academy, Ecole du Val-de-Grace, Paris, France.

Background: Anterior lumbar approach, routinely used in spinal surgery, provides many advantages, specifically avoidance of manipulation and potential injury to nervous system structures; it also provides indirect central and foraminal decompression, with a complication rate of 1%-3%. Chyloretroperitoneum is a rare complication of spinal procedures using anterior lumbar approach. The aim of this study was to discuss diagnosis, treatment, and management of chyloretroperitoneum based on review of the international literature through 2017. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S18788750183256
Publisher Site
http://dx.doi.org/10.1016/j.wneu.2018.11.018DOI Listing
November 2018
7 Reads

Objective demonstration of improvement of neurogenic bowel dysfunction in a case of spinal cord injury following stem cell therapy.

J Surg Case Rep 2018 Nov 13;2018(11):rjy300. Epub 2018 Nov 13.

General and Digestive Surgery Department, Hospital Fundación Jimenez Diaz, Madrid, Spain.

Constipation in spinal cord injury patients is a frequent complication that leads to a reduction of quality of life, extensive psychological and economic strain on patients and healthcare systems. We report a 58-year-old man with an incomplete SCI secondary to L1 vertebral fracture, presented gait disorder with neurogenic bowel and bladder dysfunction. He received 300 million autologous mesenchymal stromal cells (MSC) in the subarachnoid space by lumbar puncture. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jscr/rjy300DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232283PMC
November 2018
1 Read

Continuous spinal anaesthesia: A retrospective analysis of 318 cases.

Indian J Anaesth 2018 Oct;62(10):765-772

Department of Anaesthesia and Surgical Intensive Care, Changi General Hospital, Singapore.

Background And Aims: Continuous spinal anaesthesia (CSA) is an underutilised anaesthetic technique. Our objectives were to evaluate the use of CSA in our institution, its efficacy, ease to use and safety.

Methods: This was a retrospective analysis conducted in a tertiary centre. Read More

View Article

Download full-text PDF

Source
http://www.ijaweb.org/text.asp?2018/62/10/765/242889
Publisher Site
http://dx.doi.org/10.4103/ija.IJA_387_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190429PMC
October 2018
6 Reads

Cost of managing meningitis and encephalitis among infants and children in the United States.

Diagn Microbiol Infect Dis 2018 Oct 27. Epub 2018 Oct 27.

bioMérieux, Durham, NC; Hofstra Northwell School of Medicine, Hempstead, NY.

A retrospective cohort study design was used to assess the use and costs of diagnostic tests, medication, and total hospitalization costs for pediatric patients with suspected meningitis/encephalitis who received a lumbar puncture (LP) procedure. Related costs were calculated by timing of LP performed and infectious etiology for infants (<1 year) and children (1-17 years). A total of 3030 infants and 3635 children with suspected ME diagnosed between 2011 and 2014 were included in the study. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S07328893183054
Publisher Site
http://dx.doi.org/10.1016/j.diagmicrobio.2018.10.012DOI Listing
October 2018
8 Reads

Efficiency of dual siRNA-mediated gene therapy for intervertebral disc degeneration (IVDD).

Spine J 2018 Nov 12. Epub 2018 Nov 12.

Sunshine Medical Academy of Research and Training (SMART), Sunshine Hospitals, Hyderabad, Telangana, India. Electronic address:

Background Context: One of the common causes of low back pain is intervertebral disc degeneration. The pathophysiology of disc degeneration involves apoptosis of nucleus pulposes cells and degradation of extra cellular matrix (ECM). Caspase 3 plays a central role in apoptosis and the ADAMTS5 (A Disintegrin and Metalloproteinase with Thrombospondin motifs 5) gene plays a critical role in ECM degradation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.spinee.2018.10.016DOI Listing
November 2018
13 Reads

[A Process-Oriented Approach at Current Recommendations for Obstetric Anesthesia and Postoperative Monitoring After C-Section].

Anasthesiol Intensivmed Notfallmed Schmerzther 2018 Oct 13;53(10):696-702. Epub 2018 Nov 13.

The known guidelines before a planned operation on aspiration, fasting and preoperative risk evaluation also apply in obstetrics. Extended measures are only justified under concrete anamnestic or specific symptoms. Neuraxial anesthesia techniques should be offered to the mother as early as possible, as waiting for a certain opening of the cervix is not justified. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-0043-111309DOI Listing
October 2018
1 Read

Is the intravenous giving set a reliable alternative to the spinal manometer in measuring cerebrospinal fluid opening pressure?

S Afr Med J 2018 Oct 2;108(10):865-869. Epub 2018 Oct 2.

Department of Medicine, Edendale Hospital, Pietermaritzburg, and Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.

Background: Measurement of the cerebrospinal fluid (CSF) opening pressure (OP) during lumbar puncture (LP) should be routine practice. In resource-limited centres, spinal manometers are seldom available and alternative procedures to measure CSF OP are undertaken.

Objectives: To investigate whether the intravenous giving set (IVGS) with a measuring tape is a reliable alternative to the spinal manometer. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7196/SAMJ.2018.v108i10.13176DOI Listing
October 2018
3 Reads

Ultrasound-Assisted Lumbar Puncture in a Neuromuscular Clinic has a High Success Rate and Less Pain.

Can J Neurol Sci 2018 Nov 13:1-4. Epub 2018 Nov 13.

3Ellen and Martin Prosserman Centre for Neuromuscular Diseases,Division of Neurology,Department of Medicine,University Health Network,University of Toronto,Toronto,Canada.

Background: Lumbar puncture (LP) performed with the assistance of ultrasound (US) may improve success rate, with fewer puncture attempts and less pain.

Objectives: To explore the utility of US-assisted LP in a neuromuscular clinic.

Methods: We performed a prospective, randomized, open-label study between May 2016 and January 2017. Read More

View Article

Download full-text PDF

Source
https://www.cambridge.org/core/product/identifier/S031716711
Publisher Site
http://dx.doi.org/10.1017/cjn.2018.351DOI Listing
November 2018
6 Reads

Iatrogenic lumbar artery injury in spine surgery: a literature review.

World Neurosurg 2018 Nov 9. Epub 2018 Nov 9.

Department of Spinal Surgery, General Hospital of Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, 750004, China. Electronic address:

Objective: To review the literature related to iatrogenic lumbar artery injury (ILAI) in spine surgery with a focus on which iatrogenic operation may cause lumbar artery (LA) injury.

Methods: We conducted a comprehensive search in the Web of Science, PubMed, EMBASE and Chinese biomedical databases in July 2018.

Results: A total of 20 articles on ILAI were selected in this study, most of which were published as case reports involving a total of 26 cases. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S18788750183252
Publisher Site
http://dx.doi.org/10.1016/j.wneu.2018.10.219DOI Listing
November 2018
8 Reads
2.420 Impact Factor

Update on Modalities and Techniques for Labor Epidural Analgesia and Anesthesia.

Adv Anesth 2018 Dec 27;36(1):139-162. Epub 2018 Sep 27.

Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S07376146183000
Publisher Site
http://dx.doi.org/10.1016/j.aan.2018.07.006DOI Listing
December 2018
6 Reads

The Legacy of the Seminal Publication by Guillain, Barré, and Strohl: The History Behind the Eponym.

WMJ 2018 Oct;117(4):160-163

Department of Neurology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin,

The report, "On a syndrome of radiculoneuritis with hyperalbuminosis of the cerebrospinal fluid without a cellular reaction. Remarks on the clinical characteristics and tracings of the tendon reflexes," published in 1916, included superb longitudinal clinical observations of progressive areflexic paralysis in 2 French soldiers, unique laboratory findings from the still new at that time technique of lumbar puncture, and electrophysiological studies. The classic observation of the albumino-cytologic dissociation in the spinal fluid, even over 100 years later, is still one of the most important laboratory findings used by clinicians to confirm the suspected diagnosis of the Acute Inflammatory Demyelinating Polyneuropathy, typically eponymously referred to as Guillain Barré Syndrome (GBS). Read More

View Article

Download full-text PDF

Source
October 2018
8 Reads

Lack of antiretroviral therapy is associated with higher risk of neurosyphilis among HIV-infected patients who remain serofast after therapy for early syphilis.

Medicine (Baltimore) 2018 Nov;97(45):e13171

Department of Dermatology.

Resolution of clinical symptoms and at least 4-fold decline in nontreponemal antibody titers after treatment of syphilis is regarded as "proof of cure." However, a substantial proportion of patients demonstrates <4-fold reduction of titers after recommended therapy (serofast state). It remains unclear whether the serofast state is indicative of persistence of bacteria or only a residual immune response. Read More

View Article

Download full-text PDF

Source
http://Insights.ovid.com/crossref?an=00005792-201811090-0007
Publisher Site
http://dx.doi.org/10.1097/MD.0000000000013171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250445PMC
November 2018
11 Reads

MRI-guided intrathecal transplantation of hydrogel-embedded glial progenitors in large animals.

Sci Rep 2018 Nov 7;8(1):16490. Epub 2018 Nov 7.

Department of Neurosurgery, School of Medicine, Collegium Medicum, University of Warmia and Mazury, Olsztyn, 10-719, Poland.

Disseminated diseases of the central nervous system such as amyotrophic lateral sclerosis (ALS) require that therapeutic agents are delivered and distributed broadly. Intrathecal route is attractive in that respect, but to date there was no methodology available allowing for optimization of this technique to assure safety and efficacy in a clinically relevant setting. Here, we report on interventional, MRI-guided approach for delivery of hydrogel-embedded glial progenitor cells facilitating cell placement over extended surface of the spinal cord in pigs and in naturally occurring ALS-like disease in dogs. Read More

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41598-018-34723-x
Publisher Site
http://dx.doi.org/10.1038/s41598-018-34723-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220305PMC
November 2018
3 Reads

Risk of neurosyphilis in HIV-infected persons with syphilis lacking signs or symptoms of central nervous system infection.

HIV Med 2019 Jan 7;20(1):27-32. Epub 2018 Nov 7.

Department of Internal Medicine, University of Illinois at Chicago, Chicago, IL, USA.

Objectives: People living with HIV (PLWH) are at increased risk of asymptomatic neurosyphilis; thus, it has been common practice to perform a lumbar puncture (LP) in all PLWH presenting with syphilis regardless of stage, signs or symptoms. However, this practice varies widely among clinicians. Our objective was to elucidate the number of LPs required to diagnose a single case of asymptomatic neurosyphilis. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/hiv.12677
Publisher Site
http://dx.doi.org/10.1111/hiv.12677DOI Listing
January 2019
7 Reads

Bone morphogenetic protein 2 alleviated intervertebral disc degeneration through mediating the degradation of ECM and apoptosis of nucleus pulposus cells via the PI3K/Akt pathway.

Int J Mol Med 2019 Jan 2;43(1):583-592. Epub 2018 Nov 2.

Department of Spinal Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P.R. China.

The present study aimed to explore the underlying mechanisms of bone morphogenetic protein 2 (BMP2) in alleviating intervertebral disc degeneration (IDD). A rat puncture IDD model was constructed, and the rats were randomly divided into six groups: Control; IDD (model); IDD+PBS [containing 1010 adeno‑associated virus serotype 2 (AAV)]; and IDD + AAV2‑BMP2 (106, 108 and 1010). IL‑1β was used to treat primary nucleus pulposus (NP) cells to mimic IDD in vitro. Read More

View Article

Download full-text PDF

Source
http://www.spandidos-publications.com/10.3892/ijmm.2018.3972
Publisher Site
http://dx.doi.org/10.3892/ijmm.2018.3972DOI Listing
January 2019
2 Reads

Post-acupuncture headache: an unfortunate case of an inadvertent lumbar puncture.

Singapore Med J 2018 10;59(10):557-558

Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore.

View Article

Download full-text PDF

Source
http://www.smj.org.sg/article/post-acupuncture-headache-unfo
Publisher Site
http://dx.doi.org/10.11622/smedj.2018131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199195PMC
October 2018
3 Reads

The Procedure Coordinator: A Resident-Driven Initiative to Increase Opportunity for Inpatient Procedures.

J Grad Med Educ 2018 Oct;10(5):583-586

Background : Training residents to become competent in common bedside procedures can be challenging. Some hospitals have attending physician-led procedure teams with oversight of all procedures to improve procedural training, but these teams require significant resources to establish and maintain.

Objective : We sought to improve resident procedural training by implementing a resident-run procedure team without routine attending involvement. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4300/JGME-D-18-00399.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194897PMC
October 2018