J Dermatolog Treat 2018 Sep 10;29(6):630-632. Epub 2018 Jan 10.
a Section of Dermatology, Department of Medicine , University of Verona , Verona , Italy.
Background: Kyrle's disease (KD) is a primary perforating dermatosis that affects more commonly 30-50 year old females, and clinically characterized by pruritic hyperkeratotic and ulcerated nodules, papules and plaques, localized on extensor surface of upper and lower limbs, and on the trunk.
Objective: To determine the effectiveness of the treatment with oral isotretinoin in KD.
Methods: We present the case of a 63-year-old woman with hyperkeratotic, erythematous-brown nodules and plaques localized on arms and legs, intensely itching; some lesions were ulcerated and discharging. Read More