132,895 results match your criteria Korean circulation journal[Journal]


Multiplex PCR for the rapid detection of insulin-like growth factor in the Pacific oyster, Crassostrea gigas: a useful indicator for growth assessment.

Mol Biol Rep 2018 Dec 13. Epub 2018 Dec 13.

Department of Marine Bio-Materials & Aquaculture, Pukyong National University, Busan, 48513, South Korea.

Insulin-like growth factor (IGF) expression plays a critical role in the endocrine regulation of proliferation, differentiation, and growth in shellfish as well as in fish. The Pacific oyster, Crassostrea gigas, is a significant aquaculture species that comprises a large percentage of the Korean shellfish industry; moreover, its growth is economically important in aquaculture. However, when measuring the growth rate in shellfish, the soft tissue weight is difficult to determine because of the shell weight. Read More

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December 2018

Screening of Genetic Factor in the Interaction Between Periodontitis and Metabolic Traits Using Candidate Gene Association Study (CGAS).

Authors:
Kyung-Hui Moon

Biochem Genet 2018 Dec 13. Epub 2018 Dec 13.

Department of Dental Hygiene, Jinju Health College, Uibyeong-ro 51, Jinju, Korea.

Periodontitis has been reported to relate to metabolic syndrome traits such as obesity, blood pressure, and so on. However, the relation between periodontitis and metabolic syndrome remains unclear. The present study aimed to confirm common genetic factors between periodontitis and metabolic traits using Candidate gene association study (CGAS) in the Korean population. Read More

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December 2018

Age as a Moderator of Social Skills Intervention Response Among Korean Adolescents with Autism Spectrum Disorder.

J Autism Dev Disord 2018 Dec 13. Epub 2018 Dec 13.

Department of Psychiatry, Seoul National University Bundang Hospital, 82, Gumi-ro 173beon-gil, Bundang-gu, Seongnam, Gyeonggi, 13620, South Korea.

Few studies have investigated the effect of age on treatment effectiveness of evidence-based social skills training in autism spectrum disorder (ASD) adolescents. This study evaluated the effectiveness of Program for the Education and Enrichment of Relational Skills (PEERS) in different ages of ASD adolescents. A total of 110 ASD adolescents aged 11-19 years were divided into early, middle, and late adolescence groups, and the changes in outcome measures following intervention were compared among the three groups. Read More

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December 2018

Validation of a Multiplexed Opsonophagocytic Assay for 11 Additional Pneumococcal Serotypes and Its Application to Functional Antibody Evaluation Induced by Pneumococcal Polysaccharide Vaccine.

J Korean Med Sci 2018 Dec 12;33(51):e340. Epub 2018 Dec 12.

Department of Pediatrics, Ewha Womans University College of Medicine, Seoul, Korea.

Background: Various pneumococcal vaccines have been evaluated for immunogenicity by opsonophagocytic assay (OPA). A multiplexed OPA (MOPA) for 13 pneumococcal serotypes was developed by Nahm and Burton, and expanded to 26 serotypes in 2012. The development of new conjugate vaccines with increased valence has necessitated expanded MOPAs to include these additional serotypes. Read More

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December 2018

The Association between Frequency of Social Contact and Frailty in Older People: Korean Frailty and Aging Cohort Study (KFACS).

J Korean Med Sci 2018 Dec 3;33(51):e332. Epub 2018 Dec 3.

Jungbu Area Epidemiologic Investigation Team, Occupational Safety and Health Research Institute, Incheon, Korea.

Background: The trend of aging society is occurring globally, and with it, one of the health problems that is emerging is frailty. Efforts are being made to account for the increasing prevalence of frailty, and various modifiable factors are being considered in regards to frailty. Because social contact has shown beneficial effects in terms of health in previous studies, it is increasingly being considered in relation to frailty. Read More

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December 2018

Prevalence of Pathological Brain Lesions in Girls with Central Precocious Puberty: Possible Overestimation?

J Korean Med Sci 2018 Dec 26;33(51):e329. Epub 2018 Nov 26.

Department of Pediatrics, Ajou University School of Medicine, Ajou University Hospital, Suwon, Korea.

Background: Brain magnetic resonance imaging (MRI) is routinely performed to identify brain lesions in girls with central precocious puberty (CPP). We aimed to investigate the prevalence and type of brain lesions among Korean girls with CPP and evaluate the need for routine brain MRI examinations.

Methods: This retrospective cross-sectional study evaluated data on 3,528 girls diagnosed with CPP from April 2003 to December 2016, and identified 317 girls who underwent sellar MRI. Read More

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December 2018

Effect of National Implementation of Telephone CPR Program to Improve Outcomes from Out-of-Hospital Cardiac Arrest: an Interrupted Time-Series Analysis.

J Korean Med Sci 2018 Dec 26;33(51):e328. Epub 2018 Nov 26.

Department of Emergency Medicine, Seoul National University College of Medicine, Seoul, Korea.

Background: In cardiac arrest, the survival rate increases with the provision of bystander cardiopulmonary resuscitation (CPR), of which the initial response and treatment are critical. Telephone CPR is among the effective methods that might increase the provision of bystander CPR. This study aimed to describe and examine the improvement of neurological outcomes in individuals with out-of-hospital acute cardiac arrest by implementing the nationwide, standardized telephone CPR program. Read More

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December 2018

Efficacy of First-Line Targeted Therapy in Real-World Korean Patients with Metastatic Renal Cell Carcinoma: Focus on Sunitinib and Pazopanib.

J Korean Med Sci 2018 Dec 22;33(51):e325. Epub 2018 Nov 22.

Department of Urology, National Cancer Center, Goyang, Korea.

Background: To evaluate survival outcomes and prognostic factors for overall survival (OS) in patients with metastatic renal cell carcinoma (mRCC) who received sunitinib (SU) and pazopanib (PZ) as first-line therapy in real-world Korean clinical practice.

Methods: Data of 554 patients with mRCC who received SU or PZ at eight institutions between 2012 and 2016 were retrospectively reviewed. Based on the targeted therapy, the patients were divided into SU (n = 293) or PZ (n = 261) groups, and the clinicopathological variables and survival rates of the two groups were compared. Read More

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December 2018

Complete Recovery of Oxysterol 7α-Hydroxylase Deficiency by Living Donor Transplantation in a 4-Month-Old Infant: the First Korean Case Report and Literature Review.

J Korean Med Sci 2018 Dec 22;33(51):e324. Epub 2018 Nov 22.

Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Korea.

Oxysterol 7α-hydroxylase deficiency is a very rare liver disease categorized as inborn errors of bile acid synthesis, caused by mutations. As it may cause rapid progression to end-stage liver disease even in early infancy, a high index of suspicion is required to prevent fatal outcomes. We describe the case of a 3-month-old boy with progressive cholestatic hepatitis and severe hepatic fibrosis. Read More

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December 2018

Modulation of senoinflammation by calorie restriction based on biochemical and Omics big data analysis.

BMB Rep 2018 Dec 14. Epub 2018 Dec 14.

Department of Pharmacy, College of Pharmacy, Pusan National University, Busan 46241, Republic of Korea.

Aging is a complex and progressive process characterized by physiological and functional decline with time that increases susceptibility to diseases. Aged-related functional change is accompanied by a low-grade, unresolved chronic inflammation as a major underlying mechanism. In order to explain aging in the context of chronic inflammation, a new integrative concept on age-related chronic inflammation is necessary that encompasses much broader and wider characteristics of cells, tissues, organs, systems, and interactions between immune and non-immune cells, metabolic and non-metabolic organs. Read More

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December 2018

Treatment outcomes and factors affecting treatment outcomes of new patients with tuberculosis in Busan, South Korea: a retrospective study of a citywide registry, 2014-2015.

BMC Infect Dis 2018 Dec 13;18(1):655. Epub 2018 Dec 13.

Busan Center for Infectious Disease Control and Prevention, Pusan National University Hospital, 179 Gudeok-ro, Seo-gu, Busan, 49241, South Korea.

Background: This study investigated the treatment outcomes, and factors affecting the outcomes, of new tuberculosis (TB) patients in Busan, South Korea.

Methods: We retrospectively analysed the citywide TB registry data (collected for the Korean National TB Surveillance System) of new TB patients registered in Busan from January 2014 to December 2015.

Results: A total of 4732 patients were included in this study (mean age, 52. Read More

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December 2018

Performance of PRECISE-DAPT Score for Predicting Bleeding Complication During Dual Antiplatelet Therapy.

Circ Cardiovasc Interv 2018 Dec;11(12):e006837

Department of Clinical Epidemiology and Biostatistics, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea (S.-C.Y.).

Background: Dual antiplatelet therapy (DAPT) helps prevent ischemic events after coronary stenting but comes with an increased risk of bleeding. Several risk scores have been proposed for the management of patients receiving DAPT, but no standardized tool exists for the purpose. We sought to compare the performance of the new PRECISE-DAPT (Predicting Bleeding Complication in Patients Undergoing Stent Implantation and Subsequent Dual Antiplatelet Therapy), CRUSADE (Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes with Early Implementation of the American College of Cardiology/American Heart Association Guidelines), and ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) scores for the prediction of bleeding in Korean patients receiving DAPT. Read More

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December 2018

Association between Atmospheric Particulate Pollutants and Mortality for Cardio-Cerebrovascular Diseases in Chinese Korean Population: A Case-Crossover Study.

Int J Environ Res Public Health 2018 Dec 12;15(12). Epub 2018 Dec 12.

School of Public Health, Medical College of Qingdao University, Qingdao 266021, Shandong Province, China.

Background: Air pollution in large Chinese cities has led to recent studies that highlighted the relationship between particulate matters (PM) and elevated risk of cardio-cerebrovascular mortality. However, it is unclear as to whether: (1) The same adverse relations exist in cities with relatively low levels of air pollution; and (2) the relationship between the two are similar across ethnic groups.

Methods: We collected data of PM (PM with an aerodynamic diameter ≤ 2. Read More

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December 2018

Mesoporous Highly-Deformable Composite Polymer for a Gapless Triboelectric Nanogenerator via a One-Step Metal Oxidation Process.

Micromachines (Basel) 2018 Dec 11;9(12). Epub 2018 Dec 11.

Aircraft System Technology Group, Korea Institute of Industrial Technology (KITECH), 57, Yangho-gil, Yeongcheon-si, Gyeongbuk-do 38822, Korea.

The oxidation of metal microparticles (MPs) in a polymer film yields a mesoporous highly-deformable composite polymer for enhancing performance and creating a gapless structure of triboelectric nanogenerators (TENGs). This is a one-step scalable synthesis for developing large-scale, cost-effective, and light-weight mesoporous polymer composites. We demonstrate mesoporous aluminum oxide (Al₂O₃) polydimethylsiloxane (PDMS) composites with a nano-flake structure on the surface of Al₂O₃ MPs in pores. Read More

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December 2018

Characterization of a High PM Exposure Group in Seoul Using the Korea Simulation Exposure Model for PM (KoSEM-PM) Based on Time⁻Activity Patterns and Microenvironmental Measurements.

Int J Environ Res Public Health 2018 Dec 10;15(12). Epub 2018 Dec 10.

Department of Environmental Health Sciences, Graduate School of Public Health, Seoul National University, Seoul 08826, Korea.

The Korea Simulation Exposure Model for fine particulate matter (PM) (KoSEM-PM) was developed to estimate population PM exposure in Korea. The data were acquired based on 59,945 min of the actual microenvironmental PM measurements and on the time⁻activity patterns of 8072 residents of Seoul. The aims of the study were to estimate daily PM exposure of Seoul population, and to determine the characteristics of a high exposure group. Read More

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December 2018

Bee venom acupuncture for circumscribed morphea in a patient with systemic sclerosis: A case report.

Medicine (Baltimore) 2018 Dec;97(49):e13404

Department of Acupuncture and Moxibustion Medicine, Dongguk University Ilsan Oriental Hospital, Goyang, Republic of Korea.

Rationale: Bee venom has been reported to demonstrate antinociceptive and anti-inflammatory effects in experimental studies, but there remain questions regarding the clinical use of bee venom, especially for scleroderma. This case report shows the successful outcome of bee venom acupuncture for circumscribed morphea in a patient with systemic sclerosis, which is considered to be a rare condition.

Patient Concerns: A 64-year-old Korean woman had circular white areas (3 and 1 cm diameter) with severe itch in the right lateral iliac crest. Read More

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December 2018

Risk factor of benign paroxysmal positional vertigo in trauma patients: A retrospective analysis using Korean trauma database.

Medicine (Baltimore) 2018 Dec;97(49):e13150

Department of Trauma Surgery, Ujeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Benign paroxysmal positional vertigo (BPPV) is a comorbid condition prevalent in patients recovering from trauma. Due to the paucity of studies investigating the etiology of this condition, the present study sought to analyze the high-risk group of BPPV patients following trauma.Trauma patients visiting the emergency department from January to December 2016 were enrolled. Read More

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December 2018

Elective neurosurgical humanitarian care in a deployed setting.

Authors:

Neurosurg Focus 2018 Dec;45(6):E8

OBJECTIVEActive-duty neurosurgical coverage has been provided at Bagram Air Force Base in Afghanistan since 2007. Early operative logs were reflective of a large number of surgical procedures performed to treat battlefield injuries. However, with maturation of the war effort, the number of operations for battlefield injuries has decreased with time. Read More

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December 2018
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The shipboard Beirut terrorist bombing experience: a historical account and recommendations for preparedness in events of mass neurological injuries.

Authors:

Neurosurg Focus 2018 Dec;45(6):E18

On a Sunday morning at 06:22 on October 23, 1983, in Beirut, Lebanon, a semitrailer filled with TNT sped through the guarded barrier into the ground floor of the Civilian Aviation Authority and exploded, killing and wounding US Marines from the 1st Battalion 8th Regiment (2nd Division), as well as the battalion surgeon and deployed corpsmen. The truck bomb explosion, estimated to be the equivalent of 21,000 lbs of TNT, and regarded as the largest nonnuclear explosion since World War II, caused what was then the most lethal single-day death toll for the US Marine Corps since the Battle of Iwo Jima in World War II. Considerable neurological injury resulted from the bombing. Read More

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December 2018

A prospective, longitudinal cohort study: The impact of child maltreatment on delinquency among South Korean youth in middle and high school.

Authors:
Minhae Cho

Child Abuse Negl 2018 Dec 10;88:235-245. Epub 2018 Dec 10.

School of Social Work, University of Minnesota, Twin Cities Campus, 1404 Gortner Ave, St Paul, MN 55108, USA. Electronic address:

Background: Cultural groups vary in how they understand child maltreatment and children's misbehavior and these cultural variations may impact the relationship between maltreatment and delinquency.

Objective: This study investigated the impact of maltreatment on delinquency among South Korean youth.

Participants And Setting: Using Korean Children and Youth Panel Survey data, this study followed two cohorts of middle (n = 2,275) and high (n = 2,272) school youth for their first self-reported delinquency over 4 years. Read More

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December 2018

Effects of the Relative Distribution of Body Mass Index on the Incidence of Hypertension and Diabetes Mellitus, Using the Korean Obesity Index.

Metab Syndr Relat Disord 2018 Dec 13. Epub 2018 Dec 13.

Big Data Steering Department, National Health Insurance Service , Wonju, Korea.

Background: The Korean Obesity Index, which contains standard reference data (SRD) of obesity, was established in 2016 and revised in 2017 based on national health screening data to provide the distribution of the body mass index (BMI) of the whole population of Korea as a reference. This study aimed to investigate the effect of the SRD of obesity on the incidence of hypertension (HTN) and diabetes mellitus (DM).

Methods: The percentile of BMI was calculated for each of the 864 subgroups by defined by gender, region, and age group according to the groupings in the SRD. Read More

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December 2018

Fatty Acid- and Amino Acid-Specific Isotope Analysis for Accurate Authentication and Traceability in Organic Milk.

J Agric Food Chem 2018 Dec 13. Epub 2018 Dec 13.

The present study describes compound-specific δ13C and δ15N analyses of fatty acids and amino acids for improving the accurate authentication of organic milk (OM) against conventional milk (CM) collected in Korea. Most δ13Cfatty-acid and δ13Camino-acid values were lower in OM than in CM (P < 0.05); however, most δ15Namino-acid values displayed weak discriminative power for OM authentication. Read More

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December 2018

Influence of CYP2D6 genetic polymorphism on pharmacokinetics of active moiety of tolterodine.

Arch Pharm Res 2018 Dec 12. Epub 2018 Dec 12.

School of Pharmacy, Sungkyunkwan University, Suwon, 16419, Republic of Korea.

Tolterodine is metabolized to an active 5-hydroxymethyl tolterodine (5-HMT) by CYP2D6. This study investigated the relationship between CYP2D6 genotypes and pharmacokinetics of tolterodine and its active metabolite in healthy Korean subjects. All volunteers were genotyped for CYP2D6 and divided into four different genotype groups (CYP2D6*wt/*wt [*wt = *1 or *2], CYP2D6*wt/*10, CYP2D6*10/*10, and CYP2D6*5/*10). Read More

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December 2018

Bioactive secondary metabolites from an endophytic fungus Phoma sp. PF2 derived from Artemisia princeps Pamp.

J Antibiot (Tokyo) 2018 Dec 12. Epub 2018 Dec 12.

College of Pharmacy and Innovative Drug Center, Duksung Women's University, Seoul, 01369, Republic of Korea.

Two new isochromanone derivatives, (3S,4S)-3,8-dihydroxy-6-methoxy-3,4,5-trimethylisochroman-1-one (1) and methyl (S)-8-hydroxy-6-methoxy-5-methyl-4a-(3-oxobutan-2-yl)benzoate (2), together with six known compounds (3‒8) were isolated from the cultures of an endophytic fungus Phoma sp. PF2 obtained from Artemisia princeps. The chemical structures of the isolated compounds were elucidated by interpretation of spectroscopic data (1D, 2D NMR, HRESIMS, and CD) and calculation of ECD. Read More

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December 2018

Increased α2-6 sialylation of endometrial cells contributes to the development of endometriosis.

Exp Mol Med 2018 Dec 12;50(12):164. Epub 2018 Dec 12.

Department of Korean Medical Science, School of Korean Medicine, Seoul, Republic of Korea.

Endometriosis is a disease characterized by implants of endometrial tissue outside the uterine cavity and is strongly associated with infertility. Focal adhesion of endometrial tissue to the peritoneum is an indication of incipient endometriosis. In this study, we examined the effect of various cytokines that are known to be involved in the pathology of endometriosis on endometrial cell adhesion. Read More

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December 2018

Efficacy and safety of thread embedding acupuncture for chronic low back pain: a randomized controlled pilot trial.

Trials 2018 Dec 12;19(1):680. Epub 2018 Dec 12.

Clinical Research Division, Korea Institute of Oriental Medicine, Daejeon, 34054, Republic of Korea.

Background: We investigated the efficacy and safety of thread-embedding acupuncture (TEA) for chronic low back pain (LBP) in a randomized controlled pilot trial with the aim of laying the foundation for a large-scale randomized controlled trial on this topic.

Methods: Forty participants were recruited for this two-arm, assessor-blinded randomized controlled pilot trial. The participants were randomly allocated to a TEA group (experimental group) or an acupuncture group (control group). Read More

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December 2018

Psychometric Validation of the Korean Version of the 9-Item European Heart Failure Self-Care Behaviour Scale.

Eval Health Prof 2018 Dec 13:163278718817946. Epub 2018 Dec 13.

2 Department of Nursing, Wonkwang University, Iksan, South Korea.

Heart failure (HF) is the most common cause of frequent hospitalizations and high mortality. Active engagement in self-care behaviors is an essential component of HF disease management. Although the 9-item European Heart Failure Self-care Behaviour Scale (EHFScBS-9) as a commonly used instrument has been validated in different languages, there is no validated tool for addressing self-care behaviors related to HF in Korea. Read More

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December 2018

Esculentoside H inhibits colon cancer cell migration and growth through suppression of MMP-9 gene expression via NF-kB signaling pathway.

J Cell Biochem 2018 Dec 7. Epub 2018 Dec 7.

Molecular and Cellular Glycobiology Unit, Department of Biological Sciences, SungKyunKwan University, Chunchun-Dong, Jangan-Gu, Suwon, Kyunggi-Do, Korea.

A water-soluble saponin, Esculentoside H (EsH), 3-O-(O-β-d-glucopyranosyl-(1→4)-β-d-xylopyranosyl)-28-β-d-glucopyranosylphytolaccagenin has been isolated and purified from the root extract of perennial plant Phytolacca esculenta. EsH is known to be an anticancer compound, having a capacity for TNF-α release. However, the effects of EsH on migration and growth in tumor cells have not yet been reported. Read More

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December 2018

Kinetic Analysis of Korean Traditional Dance Movements by Using Ground Reaction Force.

Iran J Public Health 2018 Oct;47(10):1602-1603

Sports and Health Care Major, Korea National University of Transportation, Chungju-si, Korea.

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October 2018

The association between long working hours and work-related musculoskeletal symptoms of Korean wage workers: data from the fourth Korean working conditions survey (a cross-sectional study).

Ann Occup Environ Med 2018 3;30:67. Epub 2018 Dec 3.

Department of Occupational and Environmental Medicine, Soonchunhyang University Hospital, Seoul, South Korea.

Background: It has been reported that long working hours are hazardous to the workers' health. Especially, work-related musculoskeletal disorders (WMSDs) have been considered as one of the significant health issues in workplace. The objective of this study was to identify the association between long working hours and work-related musculoskeletal symptoms. Read More

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December 2018

Alleviates Oxidative Stress-Mediated Liver Injury through Activation of the CaMKK2-AMPK Signaling Pathway.

Evid Based Complement Alternat Med 2018 6;2018:8609285. Epub 2018 Nov 6.

Department of Herbal Formulation, College of Korean Medicine, Daegu Haany University, Gyeongsan 38610, Republic of Korea.

(SDT) is used frequently as a herbal prescription to treat deficiency syndromes in traditional Korean medicine. We investigated the hepatoprotective effects of SDT against oxidative stress and attempted to clarify the underlying molecular mechanisms. SDT pretreatment reduced arachidonic acid (AA) plus iron-mediated cytotoxicity in a concentration-dependent manner and prevented changes in apoptosis-related protein expression. Read More

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November 2018

High Doses of Partially Prevents Estrogen Deficiency-Induced Bone Loss With Anti-osteoclastogenic Activity Due to Enhanced iNOS/NO Signaling.

Front Pharmacol 2018 16;9:1314. Epub 2018 Nov 16.

Department of Anatomy, College of Korean Medicine, Kyung Hee University, Seoul, South Korea.

(BF) extract, a natural product with anti-inflammatory properties, has been traditionally used to treat menopausal symptoms, but its role in osteoporosis, another serious health concern of menopausal women, remains unknown. Here we investigated whether and how BF prevents estrogen deficiency-induced bone loss using both and models. Female Sprague-Dawley rats were ovariectomized (OVX) and subjected to oral BF treatment daily for 8 weeks. Read More

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November 2018

Effectiveness and Safety of Polydioxanone Thread-Embedding Acupuncture as an Adjunctive Therapy for Patients with Chronic Nonspecific Neck Pain: A Randomized Controlled Trial.

J Altern Complement Med 2018 Dec 5. Epub 2018 Dec 5.

5 Department of Neuropsychiatry, Dunsan Korean Medicine Hospital, Daejeon University , Daejeon, Republic of Korea.

Objective: To evaluate the effectiveness and safety of treatment with thread-embedding acupuncture (TEA) using polydioxanone in addition to usual care for patients with chronic nonspecific neck pain (CNP) compared with treatment with usual care alone.

Methods: A single-center, assessor-blinded, two-armed randomized controlled trial was performed. One hundred and six outpatients with CNP were randomly allocated into the TEA plus usual care (TU) group or the usual care (UC) group in a 1:1 ratio. Read More

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December 2018

Multicenter retrospective analysis of the safety and efficacy of regorafenib after progression on sorafenib in Korean patients with hepatocellular carcinoma.

Invest New Drugs 2018 Dec 7. Epub 2018 Dec 7.

Division of Hematology and Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.

Background The pivotal RESORCE trial showed that regorafenib was effective as second-line therapy for patients with advanced HCC who progressed on first-line sorafenib. Real-world data are needed to assess clinical outcomes and adverse events in the setting of daily practice. Methods Between April 2017 and August 2017, the Named Patient Program (NPP) was activated to provide controlled, pre-approval access of regorafenib in Korea. Read More

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December 2018

Intraocular pressure change after injection of intravitreal dexamethasone (Ozurdex) implant in Korean patients.

Br J Ophthalmol 2018 Dec 6. Epub 2018 Dec 6.

Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Seoul, Republic of Korea

Background/aims: To analyse intraocular pressure (IOP) changes over a period of 1 year after intravitreal dexamethasone (DEX, Ozurdex) implant injection and to compare the results with those of previously published studies that involved non-Asian populations.

Methods: A retrospective observational study was conducted. A total of 540 eyes of 503 patients who received DEX implant injection and were diagnosed with macular oedema (ME) due to various retinal diseases were examined. Read More

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December 2018

Efficacy and safety of polydioxanone thread embedded at specific acupoints for non-specific chronic neck pain: a study protocol for a randomized, subject-assessor-blinded, sham-controlled pilot trial.

Trials 2018 Dec 6;19(1):672. Epub 2018 Dec 6.

Department of Acupuncture and Moxibustion Medicine, College of Korean Medicine, Daejeon University, 62, Daehak-ro, Dong-gu, Daejeon, 34520, Republic of Korea.

Background: This study aims to evaluate the efficacy and safety of thread-embedding acupuncture (TEA) with polydioxanone thread embedded at various acupoints, compared with sham TEA, for the treatment of non-specific chronic neck pain.

Methods/design: This study will be an 8-week-long, two-armed, parallel, randomized, subject-assessor-blinded, sham-controlled pilot trial. Fifty eligible patients will be randomly allocated into the real TEA group or the sham TEA group. Read More

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December 2018
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Age-related perceptual difference of Kyungsang Korean accent contrast: A diachronic observation.

Authors:
Hyunjung Lee

J Acoust Soc Am 2018 Nov;144(5):EL367

Incheon National University, Michuhol Campus, 12 Gaetbeol-ro, Yeonsu-gu, Incheon, 21999, South Korea

This study investigated the perception of lexical pitch accent contrasts between innovative and conservative listeners under a sound change. Younger and older listeners speaking Kyungsang Korean participated in the 2AFC identification task. The participants responded to stimuli systematically varying spectral and temporal F0 properties (i. Read More

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November 2018

Twin principles for need-based attendance policy in undergraduate medical education.

Korean J Med Educ 2018 Dec 1;30(4):369-372. Epub 2018 Dec 1.

Department of Medical Education, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

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December 2018

Nurturing instead of depleting empathy during medical education: a medical student's perspective.

Authors:
Simone Chiang

Korean J Med Educ 2018 Dec 1;30(4):365-368. Epub 2018 Dec 1.

Faculty of Medicine, University of British Columbia, Vancouver, Canada.

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December 2018

Learning experience of undergraduate medical students during 'model preparation' of physiological concepts.

Korean J Med Educ 2018 Dec 1;30(4):359-364. Epub 2018 Dec 1.

Department of Physiology, Sri Manakula Vinayagar Medical College and Hospital, Puducherry, India.

Purpose: Learning physiological concepts and their practical applications in the appropriate contexts remains a great challenge for undergraduate medical students. Hence the present study aimed to analyze the learning experience of undergraduate medical students during an active learning process of 'preparation of models' depicting physiological concepts.

Methods: A total of 13 groups, involving 55 undergraduate medical students with three to five individuals in each group, were involved in model preparation. Read More

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December 2018

Comparison of results between modified-Angoff and bookmark methods for estimating cut score of the Korean medical licensing examination.

Authors:
Mikyoung Yim

Korean J Med Educ 2018 Dec 1;30(4):347-357. Epub 2018 Dec 1.

Research and Development Division, Korea Health Personnel Licensing Examination Institute, Seoul, Korea.

Purpose: The purpose of this study was to apply alternative standard setting methods for the Korean Medical Licensing Examination (KMLE), a criterion-referenced written examination, and to compare them to the conventional cut score used on the KMLE.

Methods: The process and results of criterion-referenced standard settings (i.e. Read More

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December 2018

The relationship between non-cognitive student attributes and academic achievements in a flipped learning classroom of a pre-dental science course.

Korean J Med Educ 2018 Dec 1;30(4):339-346. Epub 2018 Dec 1.

Dental Research Institute, Seoul National University School of Dentistry, Seoul, Korea.

Purpose: The purpose of this study was to examine whether non-cognitive student attributes such as learning style and personality type affected academic performance in a flipped learning classroom of a pre-dental undergraduate science course.

Methods: 'Biodiversity and Global Environment,' a 15-week, 3-credit course, was designed as a flipped class in Seoul National University School of Dentistry in 2017. Second-year pre-dental students were required to enroll in the course and to engage in online learning and in-class discussion. Read More

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December 2018

Experience of nursing students about the barriers to patient education: a qualitative study in Iran.

Korean J Med Educ 2018 Dec 1;30(4):327-337. Epub 2018 Dec 1.

Community Oriented Nursing Midwifery Research Center, Shahrekord University of Medical Sciences, Shahrekord, Ira.

Purpose: Patient education is a dynamic and continuous process that should be implemented during the entire time of hospital stay and even afterward. Studies have shown the typically poor quality of patient education in Iran and its failure to convey the required knowledge and skills to patients. The purpose of this study was to survey the experience of nursing students in regard to the challenges of patient education in hospitals. Read More

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December 2018

Effects of medical communication curriculum on perceptions of Korean medical school students.

Korean J Med Educ 2018 Dec 1;30(4):317-326. Epub 2018 Dec 1.

Division of Science Education, Chonbuk National University College of Education, Jeonju, Korea.

Purpose: The study examines changes in students' self-assessment of their general communication (GC) and medical communication (MC) competencies, as well as perceptions of MC concepts.

Methods: Participants included 108 second year medical students enrolled at a Korean medical school studying an MC curriculum. It was divided into three sections, and participants responded to questionnaires before and after completing each section. Read More

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December 2018

The development of a community-based medical education program in Korea.

Korean J Med Educ 2018 Dec 1;30(4):309-315. Epub 2018 Dec 1.

Department of Family Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea.

Purpose: The introduction of community-based medical education would help improve the quality of primary care. This paper suggests learning objectives and an educational program for community-based medical education.

Methods: The educational program was developed in a 1-day consensus workshop. Read More

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December 2018

Improving a newly adapted teaching and learning approach: Collaborative Learning Cases using an action research.

Korean J Med Educ 2018 Dec 1;30(4):295-308. Epub 2018 Dec 1.

Centre for Medical Education, Yong Loo Lin School of Medicine, National University of Singapore.

Purpose: Although medical curricula are now better structured for integration of biomedical sciences and clinical training, most teaching and learning activities still follow the older teacher-centric discipline-specific formats. A newer pedagogical approach, known as Collaborative Learning Cases (CLCs), was adopted in the medical school to facilitate integration and collaborative learning. Before incorporating CLCs into the curriculum of year 1 students, two pilot runs using the action research method was carried out to improve the design of CLCs. Read More

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December 2018

History of Japanese medical education.

Authors:
Hirotaka Onishi

Korean J Med Educ 2018 Dec 1;30(4):283-294. Epub 2018 Dec 1.

Department of International Cooperation for Medical Education, International Research Center for Medical Education, The University of Tokyo, Tokyo, Japan.

Since medical education programs in Korea and Japan seem to mutually influence each other, this review article provides a history of Japanese medical education, focusing on the way in which it influenced and was influenced by Korean medical education. In the late 19th century, the University of Tokyo established the core medical school, disseminating its scholarship and system to other medical schools. In the early 20th century, the balance between the quality and quantity of medical education became a new issue; in response, Japan developed different levels of medical school, ranging from imperial universities to medical colleges and medical vocational schools. Read More

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December 2018

It is time to reconsider the unnecessary division of premedical and medical studies.

Authors:
Young-Mee Lee

Korean J Med Educ 2018 Dec 1;30(4):279-281. Epub 2018 Dec 1.

Department of Medical Education, Korea University College of Medicine, Seoul, Korea.

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December 2018

Severe vitamin D deficiency is a risk factor for renal hyperfiltration.

Am J Clin Nutr 2018 Dec;108(6):1342-1351

Department of Internal Medicine, College of Medicine, Institute of Kidney Disease Research.

Background: Vitamin D deficiency is associated with renal progression in chronic kidney disease. Moreover, improvement of clinical outcomes after vitamin D supplementation has been reported in the diabetic and chronic kidney disease population.

Objective: We investigated the association between renal hyperfiltration (RHF) and vitamin D status in a relatively healthy population. Read More

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December 2018

Efficacy and predictors of response to inhaled corticosteroid treatment for chronic cough.

Korean J Intern Med 2018 Dec 13. Epub 2018 Dec 13.

Lung Research Institute of Hallym University College of Medicine, Chuncheon, Korea.

Background/aims: Inhaled corticosteroids (ICS) are a treatment of choice for eosinophilic airway diseases, but their efficacy for other causes of chronic cough is controversial.

Methods: We conducted a prospective observational study to determine the ICS efficacy and clinical predictors of response to ICS in patients with upper airway cough syndrome (UACS) or unexplained chronic cough (UCC). Sixty-eight patients with UACS and 33 patients with UCC (duration of cough ≥ 8 weeks) were treated with ICS: 250 µg of fluticasone propionate or 400 µg of budesonide twice a day at physician's discretion. Read More

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December 2018