132,561 results match your criteria Korean Journal of Nephrology[Journal]


Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome.

Cochrane Database Syst Rev 2018 Dec 2;12:CD011215. Epub 2018 Dec 2.

School of Korean Medicine, Pusan National University, Beom-eu, Meulgeum, Yangsan, Korea, South, 626-870.

Background: Carpal tunnel syndrome (CTS) is a compressive neuropathic disorder at the level of the wrist. Acupuncture and other methods that stimulate acupuncture points, such as electroacupuncture, auricular acupuncture, laser acupuncture, moxibustion, and acupressure, are used in treating CTS. Acupuncture has been recommended as a potentially useful treatment for CTS, but its effectiveness remains uncertain. Read More

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December 2018
3 Reads

Anthocyanins from Cornus kousa ethanolic extract attenuate obesity in association with anti-angiogenic activities in 3T3-L1 cells by down-regulating adipogeneses and lipogenesis.

PLoS One 2018 6;13(12):e0208556. Epub 2018 Dec 6.

Department of Biotechnology, Chonnam National University, Dun-Duk Dong, Yeosu, Chonnam, Korea.

Cornus kousa the Korean dogwood has been traditionally used in East Asia as therapeutic traditional medicine however biological activities of Cornus kousa have not been investigated previously. The aim of the present study was to evaluate anti-obesity activities coupled with anti-angiogenic activities of anthocyanins rich fraction of ethanolic leaf extract of Cornus kousa (ELECk) in HUVECs and 3T3- L1 cells. Dried plants leaves were extracted with 70% ethanol and anthocyanin fraction (AnT Fr) was obtained by eluting the ethanolic extract through non-polar macroporous resin and further purification by HPLC. Read More

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December 2018
1 Read

Association between metabolic parameters and glomerular hyperfiltration in a representative Korean population without chronic kidney disease.

PLoS One 2018 6;13(12):e0207843. Epub 2018 Dec 6.

Division of Endocrinology and Metabolism, Department of Internal Medicine, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, Korea.

Aims: To investigate associations of glomerular hyperfiltration with other metabolic factors in a nationally representative dataset.

Methods: We analyzed cross-sectional data from 15,918 subjects with estimated glomerular filtration rate (eGFR) >60 ml/min/1.73 m2 and urine albumin creation ratio (ACR) <30 mg/g, who participated in the 5th and 6th Korea National Health and Nutrition Examination Surveys. Read More

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December 2018

High probability areas for ASF infection in china along the russian and korean borders.

Transbound Emerg Dis 2018 Dec 6. Epub 2018 Dec 6.

Center of Conservation Medicine & Ecological Safety, Northeast Forestry University, Harbin, 150040, Heilongjiang province, P. R. China.

African swine fever (ASF) is a transcontinental, contagious, fatal virus disease of pig with devastating socioeconomic impacts. Interaction between infected wild boar and domestic pig may spread the virus. The disease is spreading fast from the west of Eurasia towards ASF-free China. Read More

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December 2018

Casticin inhibits growth and enhances ionizing radiation-induced apoptosis through the suppression of STAT3 signaling cascade.

J Cell Biochem 2018 Dec 5. Epub 2018 Dec 5.

Department of Science in Korean Medicine, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.

Casticin (CTC), one of the major components of Vitex rotundifolia L., has been reported to exert significant beneficial pharmacological activities and can function as an antiprolactin, anticancer, anti-inflammatory, neuroprotective, analgesic, and immunomodulatory agent. This study aimed at investigating whether the proapoptotic effects of CTC may be mediated through the abrogation of signal transducers and activators of transcription-3 (STAT3) signaling pathway in a variety of human tumor cells. Read More

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December 2018

Three types of a high-carbohydrate diet are differently associated with cardiometabolic risk factors in Korean adults.

Eur J Nutr 2018 Dec 5. Epub 2018 Dec 5.

Major of Food Science and Nutrition, School of Human Ecology, The Catholic University of Korea, 43 Jibong-ro, Wonmi-gu, Bucheon, 14662, Republic of Korea.

Purpose: Although a high-carbohydrate diet typically shows low-fat intake, the prevalence of metabolic abnormalities in Asian countries has increased. We evaluated three types of a high-carbohydrate diet and its association with cardiometabolic risk factors in the Korean adult population.

Methods: A total of 14,438 adults (5813 men and 8625 women) who participated in the 2008-2012 Korea National Health and Nutrition Examination Surveys were selected. Read More

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December 2018
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A Simple Guideline to Assess the Characteristics of RNA-Seq Data.

Biomed Res Int 2018 4;2018:2906292. Epub 2018 Nov 4.

Department of Microbiology, College of Natural Sciences, Dankook University, Cheonan 31116, Republic of Korea.

Next-generation sequencing (NGS) techniques have been used to generate various molecular maps including genomes, epigenomes, and transcriptomes. Transcriptomes from a given cell population can be profiled via RNA-seq. However, there is no simple way to assess the characteristics of RNA-seq data systematically. Read More

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November 2018
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Prognostic accuracy of different disseminated intravascular coagulation criteria in critically ill adult patients: a protocol for a systematic review and meta-analysis.

BMJ Open 2018 Dec 4;8(12):e024878. Epub 2018 Dec 4.

Division of Trauma and Surgical Critical Care, Osaka General Medical Center, Osaka, Japan.

Introduction: Disseminated intravascular coagulation (DIC) is a common and serious condition that can lead to poor outcomes in critically ill patients. To make a correct diagnosis and improve the outcome of patients with DIC, several organisations have put forward DIC scoring systems. However, which criteria is the best to use for diagnosing DIC remains a continuing controversy even though many studies have been conducted to validate the diagnostic accuracy of each DIC scoring system. Read More

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December 2018
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Oriental Herbal Medicine for Neurological Disorders in Children: An Overview of Systematic Reviews.

Am J Chin Med 2018 Dec 6:1-26. Epub 2018 Dec 6.

* Department of Pediatrics of Korean Medicine, Kyung Hee University, Korean Medicine Hospital at Gangdong, Seoul 05278, Republic of Korea.

Oriental herbal medicine (OHM) has been widely used in pediatric neurological disorders and has attracted attention as a safe and effective treatment. We aim to summarize and evaluate the evidence for OHM in pediatric neurological disorders for evidence-based decision-making. Without language restrictions, up-to-date research data were obtained from nine electronic databases. Read More

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December 2018
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Assessment of P values of demographic data in randomized controlled trials reported in Korean Journal of Anesthesiology between 2010 to 2017.

Korean J Anesthesiol 2018 Dec 6. Epub 2018 Dec 6.

Department of Anesthesiology and Pain Medicine, Chung-Ang University College of Medicine, Seoul, Korea.

In large number of randomized controlled trials, many of researchers would like to provide P values of demographic data which commonly described in table 1 for the purpose of emphasizing no difference between groups. The authors would intend to demonstrate that statistically insignificant P value in demographic data implicate randomization has been well performed between groups. However, insignificant P value does not necessarily reflect the successful randomization. Read More

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December 2018

Isoamericanoic Acid B from as a Potential Phytoestrogen.

Nutrients 2018 Dec 4;10(12). Epub 2018 Dec 4.

School of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea.

Phytoestrogens derived from plants have attracted the attention of the general public and the medical community due to their potentially beneficial role in relieving menopausal symptoms. The deciduous tree Maxim (Aceraceae) has long been utilized in Korean folk medicine to alleviate many physiological disorders, including abscesses, surgical bleeding, and liver diseases. In order to explore structurally and/or biologically new constituents from Korean medicinal plants, a comprehensive phytochemical study was carried out on the bark of . Read More

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December 2018

Lichen-associated bacterium, a novel bioresource of polyhydroxyalkanoate (PHA) production and simultaneous degradation of naphthalene and anthracene.

J Microbiol Biotechnol 2018 Nov 16. Epub 2018 Nov 16.

Korean Lichen Research Institute, Sunchon National University, Suncheon, Republic of Korea.

Lichens are generally known as self-sufficient symbiotic life-form between fungus and algae/cyanobacteria, also provide shelter for a wide range of beneficial bacteria. Besides, bacterial derived biodegradable polyhydroxyalkanoate (PHA) is currently grabbing the attention of many researchers as a promising alternative of non-degradable plastics. This study was conducted to develop a new method of PHA production using unexplored lichen-associated bacteria, which can simultaneously degrade two ubiquitous industrial toxins, anthracene and naphthalene. Read More

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November 2018
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Application of Artificial Intelligence in Capsule Endoscopy: Where Are We Now?

Clin Endosc 2018 Nov 30;51(6):547-551. Epub 2018 Nov 30.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.

Unlike wired endoscopy, capsule endoscopy requires additional time for a clinical specialist to review the operation and examine the lesions. To reduce the tedious review time and increase the accuracy of medical examinations, various approaches have been reported based on artificial intelligence for computer-aided diagnosis. Recently, deep learning-based approaches have been applied to many possible areas, showing greatly improved performance, especially for image-based recognition and classification. Read More

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November 2018
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Do you believe that processed EEG helps to prevent intraoperative awareness?

Authors:
Dong Woo Han

Korean J Anesthesiol 2018 Dec 30;71(6):427-429. Epub 2018 Nov 30.

Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

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December 2018
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Risk factors related to the recurrence of endometrioma in patients with long-term postoperative medical therapy.

Ginekol Pol 2018 ;89(11):611-617

Department of Obstetrics and Gynecology, Pusan National University School of Medicine Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.

Objectives: The purpose of this study was to identify clinical risk factors for the recurrence of ovarian endometrioma after ovarian cystectomy in Korean women with long-term postoperative medical therapy.

Material And Methods: A total of 134 patients who were surgically treated for endometriotic cysts at Pusan National University Hospital were included in this retrospective study. All patients received long-term postoperative medical treatment for at least 12 months after the first-line conservative surgery. Read More

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January 2018

Gender Differences in Smartphone Addiction Behaviors Associated With Parent-Child Bonding, Parent-Child Communication, and Parental Mediation Among Korean Elementary School Students.

J Addict Nurs 2018 Oct/Dec;29(4):244-254

Eun Jee Lee, PhD, RN, College of Nursing, Chonbuk National University, Jeonju, Republic of Korea. Hee Sun Kim, PhD, RN, College of Nursing, Research Institute of Nursing Science, Chonbuk National University, Jeonju, Republic of Korea.

Objective: This study investigated the gender differences in smartphone addiction (SA) behaviors associated with parent-child bonding, parent-child communication, and parental mediation among Korean elementary school students aged 11-13 years.

Method: A sample of 224 smartphone users (112 boys and 112 girls) was surveyed in a cross-sectional study. Descriptive statistics and multiple regression analysis were conducted to investigate the predictors of SA behaviors based on gender differences using SPSS Win 23. Read More

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December 2018

Sexual harassment and its relationship with depressive symptoms: A nationwide study of Korean EMS providers.

Am J Ind Med 2018 Dec 3. Epub 2018 Dec 3.

Department of Public Health Sciences, Graduate School of Korea University, Seoul, South Korea.

Background: Emergency medical service (EMS) providers may face sexual harassment (SH) from citizens. No studies have assessed SH prevalence and its association with depressive symptoms among EMS providers in South Korea.

Methods: We conducted a nationwide cross-sectional survey of 1346 EMS providers in South Korea. Read More

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December 2018

Comorbid immune-mediated diseases in inflammatory bowel disease: a nation-wide population-based study.

Aliment Pharmacol Ther 2018 Dec 2. Epub 2018 Dec 2.

Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Background: Although a higher risk of other immune-mediated diseases has been reported in inflammatory bowel disease (IBD) patients, the risk factors of immune-mediated diseases development and the effect of concomitant immune-mediated diseases on outcomes remain poorly defined.

Aim: To determine the risk factors of incident immune-mediated diseases and the impact of comorbid immune-mediated diseases on outcomes in IBD.

Methods: Using the National Health Insurance claims data for the entire Korean population, we identified 35 581 IBD patients without immune-mediated diseases and 595 IBD patients with immune-mediated diseases from 2012 to 2013, and follow-up until 2016. Read More

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December 2018

Population genetics of 19 Y-STR loci in Yanbian Korean samples from China.

Ann Hum Genet 2018 Dec 2. Epub 2018 Dec 2.

School of Forensic Medicine, China Medical University, Shenyang, 110122, China.

Background: China harbors 56 ethnic groups, including Korean, with a population size of approximately 1.92 million at the 2010 census. Most of the Koreans live in Northeastern parts of China, including Jilin (59. Read More

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December 2018

Genetic diversity and population structure of Lychnis wilfordii (Caryophyllaceae) with newly developed 17 microsatellite markers.

Genes Genomics 2018 Nov 30. Epub 2018 Nov 30.

Plant Resources Division, National Institute of Biological Resources, Incheon, 22689, Republic of Korea.

Lychnis wilfordii (Regel) Maxim. is a perennial plant designated as an endangered species by the Korean government because of rapid reduction in its population size. Thus, a population genetic study of this species is needed to establish the strategy for management and conservation based on scientific evidences. Read More

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November 2018

Association between CD53 genetic polymorphisms and tuberculosis cases.

Genes Genomics 2018 Nov 30. Epub 2018 Nov 30.

Department of Biomedical Laboratory Science, College of Life and Health Sciences, Hoseo University, Asan, Chungnam, 31499, South Korea.

Background: Tetraspanin proteins are expressed in various immune cells, and they play an important role in tuberculosis formation. CD53 is a protein in the tetraspanin family that is expressed in many white blood cells. In particular, it plays an important role in cytokine regulation and interaction between natural killer (NK) cells and antigen-presenting cells (APCs). Read More

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November 2018

A case report of traditional Korean medicine treatments on uterine myoma with thyroid cancer.

Integr Med Res 2018 Dec 25;7(4):303-306. Epub 2018 Oct 25.

Department of Korean Medicine Obstetrics & Gynecology, College of Korean Medicine, Dae-jeon University, Daejeon, Republic of Korea.

Uterine myoma is a common benign tumor. When the symptoms are not severe, patients are often suggested to wait for menopause without treatment. If the size becomes too large or the symptoms get worse, the patient will receive surgery or hormone therapy. Read More

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December 2018

The Prevalence of Cervical Foraminal Stenosis on Computed Tomography of a Selected Community-Based Korean Population.

Clin Orthop Surg 2018 Dec 21;10(4):433-438. Epub 2018 Nov 21.

Department of Orthopaedic Surgery, Daegu Catholic University Medical Center, Daegu, Korea.

Background: Cervical foraminal stenosis (CFS) is one of the degenerative changes of the cervical spine; however, correlations between the severity of stenosis and that of symptoms are not consistent in the literature. Studies to date on the prevalence of stenosis are based on images obtained from the departments treating cervical lesions, and thus patient selection bias may have occurred. The purpose of this study was to investigate the prevalence of CFS according to the site, extent, and morphology of stenosis using cervical computed tomography (CT) images obtained from patients who were visiting not because of symptoms related to the cervical spine, cervical pain, or upper limb pain. Read More

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December 2018

Discordance between Physician and the General Public Perceptions of Prognostic Disclosure to Children with Serious Illness: a Korean Nationwide Study.

J Korean Med Sci 2018 Dec 26;33(49):e327. Epub 2018 Nov 26.

Department of Biomedical Informatics, Seoul National University College of Medicine, Seoul, Korea.

Background: It is difficult to decide whether to inform the child of the incurable illness. We investigated attitudes of the general population and physicians toward prognosis disclosure to children and associated factors in Korea.

Methods: Physicians working in one of 13 university hospitals or the National Cancer Center and members of the general public responded to the questionnaire. Read More

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December 2018

Quality of Anticoagulation and Treatment Satisfaction in Patients with Non-Valvular Atrial Fibrillation Treated with Vitamin K Antagonist: Result from the KORean Atrial Fibrillation Investigation II.

J Korean Med Sci 2018 Dec 21;33(49):e323. Epub 2018 Nov 21.

Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.

Background: Vitamin K antagonist (VKA) to prevent thromboembolism in non-valvular atrial fibrillation (NVAF) patients has limitations such as drug interaction. This study investigated the clinical characteristics of Korean patients treated with VKA for stroke prevention and assessed quality of VKA therapy and treatment satisfaction.

Methods: We conducted a multicenter, prospective, non-interventional study. Read More

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December 2018

Has the Incidence of Acute Pyelonephritis Increased in Korea? - Big Data as a Double-edged Sword.

Authors:
Jin-Hong Yoo

J Korean Med Sci 2018 Dec 15;33(49):e317. Epub 2018 Nov 15.

Division of Infectious Diseases, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.

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December 2018

Estimation of the National Burden of Disease and Vulnerable Population Associated with Natural Disasters in Korea: Heavy Precipitation and Typhoon.

J Korean Med Sci 2018 Dec 14;33(49):e314. Epub 2018 Nov 14.

Department of Social and Preventive Medicine, Sungkyunkwan University School of Medicine, Suwon, Korea.

Background: Despite its growing significance, studies on the burden of disease associated with natural disasters from the perspective of public health were few. This study aimed at estimating the national burden of disease associated with typhoons and torrential rains in Korea.

Methods: During the period of 2002-2012, 11 typhoons and five torrential rains were selected. Read More

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December 2018

Ethical Priority Setting for Successful Publishing by Iranian Scientists.

J Korean Med Sci 2018 Dec 12;33(49):e313. Epub 2018 Nov 12.

Toxicology and Diseases Group, The Institute of Pharmaceutical Sciences (TIPS), and Department of Toxicology and Pharmacology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.

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December 2018

Descriptive Epidemiology of Acute Pyelonephritis in Korea, 2010-2014: Population-based Study.

J Korean Med Sci 2018 Dec 12;33(49):e310. Epub 2018 Nov 12.

Department of Internal Medicine, College of Medicine, Hanyang University, Seoul, Korea.

Background: Acute pyelonephritis (APN) is one of the most common community-acquired bacterial infections. Recent increases of antimicrobial resistance in urinary pathogens might have changed the other epidemiologic characteristics of APN. The objective of this study was to describe the current epidemiology of APN in Korea, using the entire population. Read More

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December 2018

Current Status of Pediatric Critical Care in Korea: Results of 2015 National Survey.

J Korean Med Sci 2018 Dec 12;33(49):e308. Epub 2018 Nov 12.

Department of Pediatrics, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.

Background: The aim of this study was to describe the structure, organization, management, and staffing of pediatric critical care (PCC) in Korea.

Methods: We directed a questionnaire survey for all Upper Grade General Hospitals (n = 43) in Korea in 2015. The first questionnaire was mainly about structure, organization, and staffing and responses were obtained from 32 hospitals. Read More

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December 2018
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The Symptom Trajectory of Attention-Deficit Hyperactivity Disorder in Korean School-Age Children.

Psychiatry Investig 2018 May 16;15(5):470-475. Epub 2018 May 16.

Environmental Health Center, Dankook University Hospital, Cheonan, Republic of Korea.

Objective: We aimed to investigate symptom trajectory of attention-deficit hyperactivity disorder (ADHD) in Korean school-age children.

Methods: Four hundred fifty six elementary school children were enrolled when they were in 1st grade and assessed once per year until 4th grade. Symptom severity was assessed by parents using the Korean version of the ADHD rating scale (K-ARS). Read More

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Reliability and Validity of the Korean Version of the Infant-Toddler Social and Emotional Assessment.

Psychiatry Investig 2018 May 16;15(5):460-469. Epub 2018 May 16.

Department of Psychiatry, Yonsei University College of Medicine, Seoul, Republic of Korea.

Objective: This article examined the psychometric properties of the Korean version of the Infant-Toddler Social and Emotional Assessment (K-ITSEA).

Methods: Translation and back-translation of the K-ITSEA were conducted after obtaining a permission. Two thousand two hundred thirty six Korean community infants (1,199 boys and 1,037 girls) between the ages of 12 and 36 months (M=34. Read More

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The 21-item and 12-item versions of the Depression Anxiety Stress Scales: Psychometric evaluation in a Korean population.

Asian Nurs Res (Korean Soc Nurs Sci) 2018 Nov 29. Epub 2018 Nov 29.

Uiwang-si Community Mental Health Center, Uiwang, Republic of Korea. Electronic address:

Purpose: This study aimed to evaluate the psychometric properties of the Depression Anxiety Stress Scales 21 and 12 in a Korean population.

Methods: The Depression Anxiety Stress Scales were translated into Korean using a translation and back-translation technique, and the content validity was assessed by an expert panel. Participants were recruited from 6 community health centers (n = 431) and 2 community mental health centers (n = 50). Read More

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November 2018

Easy cuts, easy rebound: Drug expenditures with massive price cuts in Korea.

Health Policy 2018 Nov 20. Epub 2018 Nov 20.

College of Nursing, Seoul National University, Seoul, Republic of Korea. Electronic address:

Backgrounds: Since 2012, the Korean government has introduced 46.5% price cut for off-patent medicines in order to reign everescalating drug expenditure. This study sought to appraise the impact of the price cut measure (in the context of Korean National Health Insurance system). Read More

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November 2018

Isolinderalactone regulates the BCL-2/caspase-3/PARP pathway and suppresses tumor growth in a human glioblastoma multiforme xenograft mouse model.

Cancer Lett 2018 Nov 29. Epub 2018 Nov 29.

Department of Korean Medical Science, School of Korean Medicine, Pusan National University, Yangsan, Gyeongnam, 50612, Republic of Korea; Korean Medical Science Research Center for Healthy-Aging, Pusan National University, Yangsan, Gyeongnam, 50612, Republic of Korea; Graduate Training Program of Korean Medicine for Healthy-Aging, Pusan National University, Yangsan, Gyeongnam, 50612, Republic of Korea. Electronic address:

Glioblastoma multiforme (GBM) is the most common malignant brain tumor, which remains incurable. Plant extracts are a potential source of potent anticancer medicines. In this study, we investigated the effect of isolinderalactone from Lindera aggregata on tumor growth using U-87 human glioblastoma cells. Read More

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November 2018
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Factors Associated with Vitamin D Status Among Korean Female Adolescents.

Authors:
Ji-Soo Kim

J Pediatr Nurs 2018 Nov 28. Epub 2018 Nov 28.

College of Nursing, Gachon University, 191 Hambakmoero, Yeonsu-gu, Incheon, 21936, Republic of Korea. Electronic address:

Purpose: The prevalence of vitamin D deficiency among female adolescents in South Korea is the highest in East Asia. Therefore, this study aims to identify factors associated with vitamin D status among female adolescents in South Korea.

Design And Methods: This cross-sectional descriptive study was conducted using a data set from the fifth Korean National Health and Nutrition Examination Survey (2010-2012). Read More

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November 2018

Gambierdiscus jejuensis sp. nov., an epiphytic dinoflagellate from the waters of Jeju Island, Korea, effect of temperature on the growth, and its global distribution.

Harmful Algae 2018 Dec 23;80:149-157. Epub 2018 Nov 23.

Department of Marine Biotechnology, College of Ocean Science and Technology, Kunsan National University, Kunsan 54150, Republic of Korea.

The genus Gambierdiscus produces ciguatera toxins, which has led to extensive studies of this genus. Epiphytic dinoflagellate cells were isolated from coralline macroalgae collected from the coastal waters of Jeju Island, Korea, and two clonal cultures were established. The morphology of these cells was examined using light and scanning electron microscopy, and the sequences of the small subunit (SSU), large subunit (LSU), and internal transcribed spacer (ITS) region of rDNA were determined. Read More

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December 2018

Postdischarge long-term cardiovascular outcomes of intensive care unit survivors who developed dialysis-requiring acute kidney injury after cardiac surgery.

J Crit Care 2018 Nov 24;50:92-98. Epub 2018 Nov 24.

Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea; Kidney Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address:

Purpose: Dialysis-requiring acute kidney injury (AKI-D) after cardiac surgery is a major cause of in-hospital mortality. However, the long-term outcome has not been previously examined.

Materials And Methods: We performed a nationwide, population-based cohort study using the claims data in the Korean National Health Insurance System. Read More

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November 2018

Genetic diversity and haplotype structure of 27 Y-STR loci in a Yanbian Korean population from Jilin Province, Northeast China.

Leg Med (Tokyo) 2018 Nov 22;36:110-112. Epub 2018 Nov 22.

Institute of Forensic Medicine and Laboratory Medicine, Jining Medical University, Forensic Science Center of Jining Medical University, Jining, Shandong 272067, PR China. Electronic address:

In this study, 27 Y-STRs were analyzed in 347 male individuals from the Yanbian Korean population. Haplotype diversity (HD) and discrimination capacity (DC) values were calculated. Pairwise R values were evaluated in AMOVA analysis and visualized through multidimensional scaling (MDS). Read More

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November 2018

Genetic variants of PARK genes in Korean patients with early-onset Parkinson's disease.

Neurobiol Aging 2018 Nov 7. Epub 2018 Nov 7.

Green Cross Genome, Yongin, Gyeonggi-do, Republic of Korea. Electronic address:

Early-onset Parkinson's disease (EOPD) can be linked to different genetic backgrounds depending on the disease characteristics. In Korean patients with EOPD, however, only 5 PARK genes have been tested. We recruited 70 patients with EOPD from 4 hospitals in Korea, and 12 PARK genes were screened via multigene panel sequencing. Read More

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November 2018

Identification and Characterization of MicroRNAs Associated with Somatic Copy Number Alterations in Cancer.

Cancers (Basel) 2018 Nov 29;10(12). Epub 2018 Nov 29.

School of Electrical Engineering and Computer Science, Gwangju Institute of Science and Technology, Gwangju 61005, Korea.

MicroRNAs (miRNAs) are key molecules that regulate biological processes such as cell proliferation, differentiation, and apoptosis in cancer. Somatic copy number alterations (SCNAs) are common genetic mutations that play essential roles in cancer development. Here, we investigated the association between miRNAs and SCNAs in cancer. Read More

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November 2018

Differences in heritability of craniofacial skeletal and dental characteristics between hypo- and hyper-divergent patterns using Falconer's method and principal component analysis.

Angle Orthod 2018 Dec 5. Epub 2018 Dec 5.

Objectives:: To investigate the difference in heritability of craniofacial skeletal and dental characteristics between hypodivergent and hyperdivergent patterns.

Materials And Methods:: 53 Korean adult monozygotic (MZ) and dizygotic (DZ) twins and their siblings were divided into a hypodivergent group (Group 1, SN-MP < 35°, 17 MZ pairs; 11 DZ and sibling [DS] pairs of the same gender) and hyper-divergent group (Group 2, SN-MP > 35°, 16 MZ pairs; 9 DS pairs of the same gender). A total of 56 cephalometric variables were measured using lateral cephalographs. Read More

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December 2018

Cancer site differences in the health-related quality of life of Korean cancer survivors: Results from a Population-based Survey.

Public Health Nurs 2018 Dec 4. Epub 2018 Dec 4.

College of Nursing Science, Kyung Hee University, Seoul, South Korea.

Objectives: We investigated cancer site differences in the health-related quality of life (HRQOL) of cancer survivors.

Design And Sample: A secondary data analysis was conducted using the sixth Korea National Health and Nutrition Examination Survey (2013-2015). Participants were 15,461 adults (664 cancer survivors) with available EuroQol-5 Dimensions (EQ5D) information. Read More

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December 2018

Understanding the adoption of new drugs decided by several stakeholders in the South Korean market: a nonparametric event history analysis.

Authors:
Kyung-Bok Son

Health Econ Rev 2018 Dec 4;8(1):31. Epub 2018 Dec 4.

College of Pharmacy, Ewha Womans University, 52Ewhayeodae-gil, Seodaemun-gu, Seoul, 03760, South Korea.

Background: Regulatory approval and reimbursement decisions are necessary if new drugs are to become accessible in a timely manner. However, the process of regulatory approval and the establishment of reimbursement decisions varies across countries. This study aims to analyze the duration between regulatory approval and reimbursement decision for new drugs and to evaluate various factors affecting the timely availability of new medicines in the Korean market. Read More

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December 2018

Impact of a school-based culinary nutrition education program on vegetable consumption behavior, intention, and personal factors among Korean second-graders.

Nutr Res Pract 2018 Dec 30;12(6):527-534. Epub 2018 Nov 30.

Department of Food and Nutrition, Chungbuk National University, Chungdae-ro 1, Seowon-gu, Cheongju, Chungbuk 28644, Korea.

Background/objectives: Veggiecation was developed to improve children's vegetable consumption through classroom lecture and cooking activities. In this study, we explored potential determinants of vegetable consumption behavior and intention, and examined the impact of Veggiecation on vegetable consumption behavior, intention and personal factors among Korean children.

Materials/methods: The 4-week Veggiecation program was implemented for second-graders in South Korea (35 children in the intervention group, 36 in the control group). Read More

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December 2018

Evaluation of in vitro anti-oxidant and anti-inflammatory activities of Korean and Chinese .

Nutr Res Pract 2018 Dec 16;12(6):486-493. Epub 2018 Nov 16.

Department of Food and Nutrition, College of BioNano Technology, Gachon University, 1342, Seongnam-daero, Sujeong-gu, Seongnam, Gyeonggi 13120, Korea.

Background/objectives: The honeysuckle berry (HB) contains ascorbic acid and phenolic components, especially anthocyanins, flavonoids, and low-molecular-weight phenolic acids. In order to examine the potential of HB as a hepatoprotective medicinal food, we evaluated the anti-oxidant and anti-inflammatory activities of Korean HB (HBK) and Chinese HB (HBC).

Materials/methods: Antioxidant and anti-inflammatory effects of the extracts were examined in HepG2 and RAW 264. Read More

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December 2018

Evidence-based approaches for establishing the 2015 Dietary Reference Intakes for Koreans.

Nutr Res Pract 2018 Dec 30;12(6):459-468. Epub 2018 Nov 30.

Department of Food and Nutrition, Chung-Ang University, 4726, Seodong-daero, Daedeok-myeon, Anseong, Gyeonggi-do 17546, Korea.

Background/objectives: The Dietary Reference Intakes for Koreans (KDRIs), a set of reference intake values, have served as a basis for guiding a balanced diet that promotes health and prevents disease in the general Korean population. In the process of developing DRIs, a systematic review has played an important role in helping the DRI committees make evidence-based and transparent decisions for updating the next DRIs. Thus, the 2015 KDRI steering committee applied the systematic review framework to the revision process of the KDRIs. Read More

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December 2018
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GC/MS-Based Metabolomics Reveals Biomarkers in Asthma Murine Model Modulated by .

Evid Based Complement Alternat Med 2018 1;2018:1202860. Epub 2018 Nov 1.

School of Korean Medicine, Dongshin University, Naju 58245, Republic of Korea.

GC/MS coupled with multivariate statistical analysis was performed to identify marker metabolites in serum of mice after healing ovalbumin- (OVA-) induced asthma using . Principal component analysis (PCA) score plot showed separation among groups, with metabolite profiles of serum showing differences according to various treatments for the asthma murine model. Levels of stearic acid and arachidic acid were significantly lower in the serum from OVA-induced group than those from the control group. Read More

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November 2018

Projected lifetime cancer risks from occupational radiation exposure among diagnostic medical radiation workers in South Korea.

BMC Cancer 2018 Dec 4;18(1):1206. Epub 2018 Dec 4.

Department of Preventive Medicine, Korea University College of Medicine, 73, Inchon-ro, Seongbuk-gu, Seoul, 02841, South Korea.

Background: Timely assessment of cancer risk from current radiation exposure among medical radiation workers can contribute to the development of strategies to prevent excessive occupational radiation exposure. The purpose of the present study is to estimate the lifetime risk of cancers induced by occupational radiation exposure among medical radiation workers.

Methods: Using estimated organ doses and the RadRAT risk assessment tool, the lifetime cancer risk was estimated among medical radiation workers who were enrolled in the Korean National Dose Registry from 1996 to 2011. Read More

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December 2018