1,191 results match your criteria Knee Osteochondritis Dissecans


Treatment of Knee Osteochondral Fractures.

Healthcare (Basel) 2022 Jun 8;10(6). Epub 2022 Jun 8.

Department of Morphological Sciences, Carol Davila University of Medicine and Pharmacy, RO-020021 Bucharest, Romania.

Osteochondral lesions (OCLs) that are frequently encountered in skeletally immature and adult patients are more common than once thought, and their incidence rate is rising. These lesions can appear in many synovial joints of the body, such as the shoulder, elbow, hip, and ankle, occurring most often in the knee. The term osteochondral lesion includes a vast spectrum of pathologies such as osteochondritis dissecans, osteochondral defects, osteochondral fractures, and osteonecrosis of the subchondral bone. Read More

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Chitosan based scaffold applied in patellar cartilage lesions showed positive clinical and MRI results at minimum 2 years of follow up.

Knee Surg Sports Traumatol Arthrosc 2022 Jun 9. Epub 2022 Jun 9.

Clinica Ortopedica e Traumatologica 2, IRCCS Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136, Bologna, Italy.

Purpose: New scaffold-based cartilage regeneration techniques have been developed to improve the results of microfractures also in complex locations like the patello-femoral joint. The aim of this study was to analyse the results obtained in patellar lesions treated with a bioscaffold,  a mixture composed by a chitosan solution, a buffer, and the patient's whole blood  which forms a stable clot into the lesion.

Methods: Fifteen patients with ICRS grade 3-4 cartilage lesions of the patellar surface were treated with a chitosan bioscaffold. Read More

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Vascularity of the early post-natal human distal femoral chondroepiphysis: Quantitative MRI analysis.

J Child Orthop 2022 Apr 30;16(2):152-158. Epub 2022 Apr 30.

Miami Orthopedic & Sports Medicine Institute, Baptist Health South Florida, Miami, FL, USA.

Purpose: Injury to or abnormality of developing distal femoral chondroepiphysis blood supply has been implicated in osteochondritis dissecans development. Progressive decrease in epiphyseal cartilage blood supply occurs in normal development; however, based on animal studies, it is hypothesized that there is greater decrease in regions more prone to osteochondritis dissecans lesions. We aimed to quantify differential regional perfusion of the immature distal femoral chondroepiphysis. Read More

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Gel-Based Autologous Chondrocyte Implantation in a Patient with Noncontained Osteochondral Knee Defect at 9-Year Follow-Up.

Case Rep Orthop 2022 16;2022:6946860. Epub 2022 May 16.

Department of Orthopedics, Civil Hospital, Bhavnagar, Gujarat, India.

Osteochondritis dissecans (OCD) is a disorder of the subchondral bone affecting the adjacent articular cartilage that may lead to cartilage and bone fragment detachment. It commonly occurs in the knee joint, elbow, wrist, and ankle. Although several surgical concepts have been described to treat OCD (fragment fixation, microfracture, autologous chondrocyte implantation (ACI), and mosaicplasty), no gold standard treatment has been accepted for managing OCD. Read More

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A systematic review of cartilage procedures for unstable osteochondritis dissecans.

Phys Sportsmed 2022 May 31:1-9. Epub 2022 May 31.

Division of Sports Medicine, Rothman Orthopaedic Institute, Philadelphia, PA, USA.

Objectives: Osteochondritis dissecans can result in significant limitations in activity, pain, and early osteoarthritis. There are various treatment modalities to address these defects. The purpose of this study was to provide a qualitative summary of the various treatment options for unstable osteochondritis dissecans in the knee. Read More

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Arthroscopic Drilling for Stable Juvenile Osteochondritis Dissecans of the Knee Is Safe and Patients Reliably Return to Daily Activities by 3 Months.

Arthrosc Sports Med Rehabil 2022 Apr 15;4(2):e645-e651. Epub 2022 Feb 15.

Division of Orthopaedics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, U.S.A.

Purpose: To assess the postoperative timeline for the return to activities of daily living (ADLs) in pediatric patients after arthroscopic drilling of a stable osteochondritis dissecans (OCD) lesion of the knee and to determine the rate of and risk factors for complications after the procedure.

Methods: In a retrospective chart review, data from all patients aged 18 years or younger who underwent arthroscopic drilling for a stable OCD lesion of either femoral condyle from May 2009 through July 2017 were collected. Demographic data, lesion characteristics, operative data, postoperative course, radiographic outcomes, and complications were recorded. Read More

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Longitudinal 3T MRI T * mapping of Juvenile osteochondritis dissecans (JOCD) lesions differentiates operative from non-operative patients-Pilot study.

J Orthop Res 2022 Apr 17. Epub 2022 Apr 17.

Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota, USA.

Juvenile osteochondritis dissecans (JOCD) is an orthopedic joint disorder of children and adolescents that can lead to premature osteoarthritis. Thirteen patients (mean age: 12.3 years, 4 females), 15 JOCD-affected and five contralateral healthy knees, that had a baseline and a follow-up magnetic resonance imaging (MRI) (mean interval of 8. Read More

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The "hump" a new arthroscopic phenomenon guiding for reliable therapy of osteochondritis dissecans of variable stability status.

Arch Orthop Trauma Surg 2022 Apr 2. Epub 2022 Apr 2.

Department of Trauma and Orthopaedic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Introduction: Despite 150 years of research, there are currently no reliable morphological characteristics that can be used to differentiate between stable and unstable juvenile osteochondritis dissecans (JOCD) lesions in the knee joint. Arthroscopic probing is still the gold standard. In arthroscopic evaluation, a previously undescribed pattern of a cartilaginous convex elevation ("hump") was identified as a new feature and potential sign of JOCD in transition to instability. Read More

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Comparison of the Healing Outcomes of Conservative Treatment for Stable Juvenile Osteochondritis Dissecans of the Lateral Femoral Condyle With Normal Lateral Meniscus and Incomplete Discoid Lateral Meniscus.

J Pediatr Orthop 2022 Jul 29;42(6):e649-e655. Epub 2022 Mar 29.

Department of Orthopaedic Surgery, Shimada Hospital, Habikino.

Background: This study aimed to compare the healing outcomes of conservative treatment for osteochondritis dissecans (OCD) of the lateral femoral condyle with normal lateral meniscus and incomplete discoid lateral meniscus (DLM).

Methods: Forty-four knees in 37 juvenile patients (mean age 9.9 y) with stable OCD and whose lateral meniscus shape was normal or incomplete DLM were enrolled. Read More

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Males and Females Exhibit Comparable Outcomes Following Treatment of OCD Lesions of the Knee: A Systematic Review.

Arthroscopy 2022 Mar 23. Epub 2022 Mar 23.

Department of Orthopaedic Surgery, Tulane University School of Medicine, New Orleans, Louisiana, U.S.A. Electronic address:

Purpose: The purpose of this study was to evaluate the impact of patient sex on outcomes after treatment of osteochondritis dissecans (OCD) lesions of the knee through a systematic review of current evidence.

Methods: This review was conducted according to the PRISMA guidelines using the PubMed, PubMed Central, Embase, Ovid Medline, Cochrane Libraries, and the Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases. Relevant outcomes included functional (e. Read More

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Validation of a Novel Magnetic Resonance Imaging Classification for Osteochondritis Dissecans of the Knee.

J Pediatr Orthop 2022 May-Jun 01;42(5):e486-e491

Division of Sports Medicine, Department of Orthopaedic Surgery, Boston Children's Hospital.

Background: The novel Kocher classification is a 3-group magnetic resonance imaging (MRI) classification system for osteochondritis dissecans (OCD) of the knee that was shown to have comparable reliability to that of the established 5-group Hefti classification. The purpose of this study was to evaluate the validity and clinical utility of this simplified system as an alternative to the Hefti classification.

Methods: Demographic data and arthroscopic findings were retrospectively collected from medical and surgical records of 144 consecutive knees in children with arthroscopically diagnosed knee OCD. Read More

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Osteochondral Allograft for Unsalvageable Osteochondritis Dissecans in the Skeletally Immature Knee.

Orthop J Sports Med 2022 Feb 11;10(2):23259671211072515. Epub 2022 Feb 11.

University of Texas Southwestern Medical Center, Dallas, Texas, USA.

Background: While an excellent option for osteochondral defects in the adult knee, fresh osteochondral allograft (FOCA) in the skeletally immature adolescent knee has been infrequently studied.

Purpose: To compare radiographic and patient-reported outcomes (PROs) in skeletally mature and immature adolescents after FOCA in the knee for treatment of unsalvageable osteochondritis dissecans (OCD).

Study Design: Cohort study; Level of evidence, 3. Read More

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February 2022

Differences in Clinical and Functional Outcomes Between Osteochondral Allograft Transplantation and Autologous Chondrocyte Implantation for the Treatment of Focal Articular Cartilage Defects.

Orthop J Sports Med 2022 Feb 9;10(2):23259671211058425. Epub 2022 Feb 9.

Thomas Jefferson Rothman Orthopedic Institute, Philadelphia, Pennsylvania, USA.

Background: Articular cartilage pathology can result from a spectrum of origins, including trauma, osteochondritis dissecans, avascular necrosis, or degenerative joint disease.

Purpose: To compare the differences in clinical and patient-reported outcomes after autologous chondrocyte implantation (ACI) versus osteochondral allograft transplantation (OCA) in patients with focal articular cartilage defects without underlying bone loss.

Study Design: Cohort study; Level of evidence, 3. Read More

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February 2022

Association of Body Mass Index With Severity and Lesion Location in Adolescents With Osteochondritis Dissecans of the Knee.

Orthop J Sports Med 2021 Sep 23;9(9):23259671211045382. Epub 2021 Sep 23.

Pediatric Division, Department of Orthopaedics, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Background: The association between body mass index (BMI) and severity of osteochondritis dissecans (OCD) of the knee at presentation is poorly understood.

Hypothesis: We hypothesized that adolescents in higher BMI percentiles for age and sex would have OCD lesions that were more severe at their initial presentation and located more posteriorly on the condyle as compared with adolescents in lower BMI percentiles.

Study Design: Cohort study; Level of evidence, 3. Read More

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September 2021

Osteocondritis dissecans lesions of the knee restored by bone marrow aspirate concentrate. Clinical and imaging results in 18 patients.

Eur J Orthop Surg Traumatol 2022 Feb 8. Epub 2022 Feb 8.

I Orthopaedic and Traumatology Clinic, Rizzoli Orthopaedic Institute - Bologna, Viale G. C. Pupilli, 1 - 40100, Bologna, Italy.

Background: Osteochondritis dissecans (OCD) is a common cartilage disorder that specifically affects the knees of skeletally immature and young adult patients. There have been a few treatments that have been proposed: fixation of the fragment, drilling, microfractures. The aim of this study was to analyze retrospectively clinical and imaging results obtained by treating it with one-step bone marrow-derived cells Transplantation (BMDCT) technique. Read More

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February 2022

What Do We Currently Know About Patellofemoral Osteochondritis Dissecans?

Cartilage 2022 Jan-Mar;13(1):19476035221075948

Department of Radiology, Istituto Clinico S. Anna, Brescia, Italy.

Objective: Knee osteochondritis dissecans (OCD) is a still poorly understood pathological condition of the articular subchondral bone and its overlying cartilage. Patellofemoral involvement accounts for less than 1% of cases; tibial plateau and multifocal involvement is an even rarer instance. The purpose of this study is to review what is currently known about patellofemoral OCD (PF-OCD) and to present an unusual case of PF-OCD which progressed to become multifocal in an adult female patient. Read More

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Osteochondritis dissecans of the patella: a case-report in a juvenile football player.

Sci Med Footb 2021 08 14;5(3):250-253. Epub 2020 Dec 14.

Sporting Clube de Portugal, Football Club, Lisbon, Portugal.

Osteochondritis dissecans (OCD) lesions are a rare cause of joint pain. Most often they occur in the knee, but they can occur in elbow or ankle too. They have a predilection for the immature skeleton and are most commonly seen in male sex, athletically active young children and adolescents. Read More

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Repair of Osteochondritis Dissecans of the Lateral Femoral Condyle by a Trochlea Osteochondral Autograft: A Case Report.

JBJS Case Connect 2022 01 20;12(1). Epub 2022 Jan 20.

Department of Orthopaedic Surgery, Gifu University Graduate School of Medicine, Gifu City, Japan.

Case: A 17-year-old adolescent boy with large deep osteochondritis dissecans (OCD) of the right lateral femoral condyle was treated with ipsilateral trochlea osteochondral autograft transplantation combined with iliac cancellous bone grafting to the donor site of the lateral trochlea. Both autografts were fused 3 months after surgery. It was radiographically confirmed that the OCD lesion was successfully reconstructed. Read More

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January 2022

Clinical phenotype and musculoskeletal characteristics of patients with aggrecan deficiency.

Am J Med Genet A 2022 04 9;188(4):1193-1203. Epub 2022 Jan 9.

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

Aggrecan is a proteoglycan within the physeal and articular cartilage. Aggrecan deficiency, due to heterozygous mutations in the ACAN gene, causes dominantly inherited short stature and, in many patients, early-onset osteoarthritis and degenerative disc disease. We aimed to further characterize this phenotypic spectrum with an emphasis on musculoskeletal health. Read More

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Incidence of Subsequent Surgical Intervention at Short-term Follow-up in Previously Healing and Stable Juvenile Osteochondritis Dissecans of the Knee.

J Pediatr Orthop 2022 Mar;42(3):e271-e276

Orthopaedic Surgery, University of Michigan, Ann Arbor, MI.

Background: Juvenile osteochondritis dissecans (OCD) of the knee is a defect of subchondral bone seen primarily in active children and adolescents. Studies have evaluated the incidence of surgery in knee OCD, but the incidence of subsequent surgery in patients with stable, healing lesions cleared to return to activities is unknown. This study sought to determine the incidence of surgery in participants with knee OCD lesions cleared to return to activities and evaluate predictors of subsequent surgery. Read More

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Imaging Pitfall in the Pediatric Knee: Irregular Epiphyseal Ossification at the Femoral Condyle.

J Belg Soc Radiol 2021 10;105(1):84. Epub 2021 Dec 10.

King's College Hospital, London, GB.

Age-related variability in endochondral ossification of the femoral condyles in children is a normal variant of skeletal maturation and should not be misdiagnosed as osteochondritis dissecans or any other epiphyseal abnormality. Read More

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December 2021

Osteochondritis Dissecans Lesion of the Trochlear Groove: A Case of Nonsurgical Management for a Rare Lesion.

Case Rep Orthop 2021 13;2021:9776362. Epub 2021 Dec 13.

Jameson Crane Sports Medicine Institute, The Ohio State University Wexner Medical Center, 2835 Fred Taylor Dr., Columbus, Ohio 43202, USA.

Osteochondritis dissecans (OCD) lesions are potential causes of knee pain in pediatric patients, with lesions most frequently found on the lateral and medial femoral condyles. This case discusses an OCD lesion of the trochlear groove, a rare location for OCD lesions, in an 11-year-old female athlete. The patient presents after several years of knee pain that had acutely worsened, and both X-ray and MRI demonstrated the lesion, with MRI confirming a stable lesion. Read More

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December 2021

Variable expressivity in a family with an aggrecanopathy.

Mol Genet Genomic Med 2022 01 10;10(1):e1773. Epub 2021 Dec 10.

Shriners Hospitals for Children, Montreal, Quebec, Canada.

Background: Osteochondritis dissecans is a condition wherein there is a subchondral bone lesion that causes pain, inflammation, and cartilage damage. Dominant Familial Osteochondritis Dissecans is a rare and severe form of osteochondritis dissecans (OCD). It is caused by heterozygous pathogenic variants in the gene encoding Aggrecan; ACAN. Read More

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January 2022

Treatment of knee osteochondritis dissecans with autologous tendon transplantation: Clinical and radiological results.

World J Orthop 2021 Nov 18;12(11):867-876. Epub 2021 Nov 18.

Department of Orthopedics and Traumatology, Erzurum Regional Training and Research Hospital, Erzurum 25070, Turkey.

Background: Defect treatment with tendon autograft in osteochondral lesions has been published in the literature with an experimental study in dogs. To demonstrate that it is possible to treat knee osteochondral lesions with the technique of autologous tendon transplantation.

Aim: To evaluate the clinical and radiological results of patients with knee osteochondral lesions who were treated with autologous tendon transplantation. Read More

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November 2021

Fresh Osteochondral Allograft Transplantation in Osteochondritis Dissecans in the Knee Joint.

Life (Basel) 2021 Nov 8;11(11). Epub 2021 Nov 8.

Reconstructive Orthopaedic Surgery and Innovative Techniques-Musculoskeletal Tissue Bank, IRCCS Istituto Ortopedico Rizzoli, Via G.C. Pupilli 1, 40136 Bologna, Italy.

Osteochondritis dissecans (OCD) is a chronic and painful joint condition that can occur from childhood through to adult life. Microtrauma, vascular insufficiency, or abnormal endochondral ossification are the most common causes of OCD. Reconstructive techniques for OCD of the knee are typically necessary when either non-operative or reparative/regenerative operative treatments fail, or when the OCD is irreversible. Read More

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November 2021

Descriptive Epidemiology From the Research in Osteochondritis Dissecans of the Knee (ROCK) Prospective Cohort.

Am J Sports Med 2022 01 24;50(1):118-127. Epub 2021 Nov 24.

The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

Background: Osteochondritis dissecans (OCD) occurs most commonly in the knees of young individuals. This condition is known to cause pain and discomfort in the knee and can lead to disability and early knee osteoarthritis. The cause is not well understood, and treatment plans are not well delineated. Read More

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January 2022

Internal Fixation of Lateral Trochlear Groove Osteochondritis Dissecans With Simultaneous Lateral Retinacular Lengthening in Adolescent Athletes.

Am J Sports Med 2021 12 10;49(14):3867-3875. Epub 2021 Nov 10.

Department of Orthopedic Surgery, Myongji Hospital, Goyang-si, Korea.

Background: The goals of operative treatment for the adolescent athlete with unstable osteochondritis dissecans (OCD) lesion are rigid fixation and prevention of recurrence.

Purpose: To evaluate clinical and radiological outcomes of internal fixation of lateral trochlear groove OCD with simultaneous lateral retinacular lengthening.

Study Design: Case series; Level of evidence, 4. Read More

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December 2021

Arthroscopic Fixation of Knee Femoral Condyle Osteochondritis Dissecans Fragment With Bone Marrow Aspirate Concentrate.

Arthrosc Tech 2021 Oct 21;10(10):e2357-e2363. Epub 2021 Sep 21.

Department of Orthopaedic Surgery, Louisiana State University, Shreveport, Louisiana, U.S.A.

This article reviews a technique for arthroscopic fixation of an osteochondritis dissecans fragment with bone marrow aspirate concentrate augmentation. This technique involves safe harvest of bone marrow arthroscopically from the intercondylar notch, proper preparation and debridement of the parent bone, reduction of the progeny osteochondritis dissecans fragment, insertion of the bone marrow aspirate concentrate, and placement of multiple headless compression screws for fixation. Read More

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October 2021

Treatment Decisions in Pediatric Sports Medicine: Do Personal and Professional Bias Affect Decision-Making?

Orthop J Sports Med 2021 Oct 14;9(10):23259671211046258. Epub 2021 Oct 14.

Rady Children's Hospital, San Diego, California, USA.

Background: Personal and professional biases can affect decision-making regarding important issues in pediatric sports medicine. Gaining insight into the opinions of health care professionals who specialize in pediatric sports medicine will provide information that may be useful for directing ongoing research in this field.

Hypothesis: It was hypothesized that surgeons would demonstrate bias toward early surgical intervention versus nonsurgeons. Read More

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October 2021

Assessment and Management of Loose Bodies in the Knee Joint and Related Disease: A Narrative Review.

Curr Rheumatol Rev 2022 ;18(1):12-19

Orthopaedic Department, Villa Erbosa Hospital, Via Dell'Arcoveggio 50/2, 40129, Bologna, Italy.

Background: Loose bodies are frequently encountered during clinical activity and are a common finding during knee arthroscopy. Usually, treatment consists of the removal of loose bodies, which can be challenging even for experienced surgeons. The excision alone is not always the complete treatment, because loose bodies are generally secondary to other diseases that can cause persistent symptoms with the risk of new loose body formation. Read More

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