89,058 results match your criteria Knee Joint


Examination of ankle function in individuals with a history of ACL reconstruction.

Phys Ther Sport 2019 Jan 10;36:55-61. Epub 2019 Jan 10.

Sports Medicine Research Institute, University of Kentucky, 720 Sports Center Drive, Lexington, KY, 40536, USA.

Objective: To determine the relationship between self-reported ankle and knee function, and to examine differences in ankle function between healthy and injured limbs in individuals with a history of ACL reconstruction (ACLR).

Design: Cross-sectional.

Setting: Laboratory. Read More

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http://dx.doi.org/10.1016/j.ptsp.2019.01.002DOI Listing
January 2019

Knee psoriatic enthesitis assessed using Positron Emission Tomography (PET)- FNa merged to ultrahigh field magnetic resonance imaging (UHF-MRI).

Joint Bone Spine 2019 Jan 17. Epub 2019 Jan 17.

Aix-Marseille University, CRMBM-CEMEREM, UMR CNRS 7339, 13385 Marseille, France; Department of Rheumatology, AP-HM, Aix-Marseille University, 13274 Marseille, France. Electronic address:

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http://dx.doi.org/10.1016/j.jbspin.2019.01.002DOI Listing
January 2019

The Evolving Large-Strain Shear Responses of Progressively Osteoarthritic Human Cartilage.

Osteoarthritis Cartilage 2019 Jan 17. Epub 2019 Jan 17.

University of Connecticut, Department of Mechanical Engineering, Storrs, CT, USA; University of Connecticut, Department of Biomedical Engineering, Storrs, CT, USA. Electronic address:

Objective: The composition and structure of articular cartilage evolves during the development and progression of osteoarthritis (OA) resulting in changing mechanical responses. We aimed to assess the evolution of the intrinsic, large-strain mechanics of human articular cartilage-governed by collagen and proteoglycan and their interactions-during the progression of OA.

Design: We completed quasi-static, large-strain shear tests on 64 specimens from ten donors undergoing total knee arthroplasty, and quantified the corresponding state of OA (OARSI grade), structural integrity (PLM score), and composition (glycosaminoglycan and collagen content). Read More

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http://dx.doi.org/10.1016/j.joca.2018.12.025DOI Listing
January 2019

Comparison of patency rates of lymphaticovenous anastomoses at different sites for lower extremity lymphedema.

J Vasc Surg Venous Lymphat Disord 2019 Jan 16. Epub 2019 Jan 16.

Department of Plastic and Reconstructive Surgery, Yamato Municipal Citizen's Hospital, Kanagawa, Japan.

Objective: Lymphaticovenous anastomosis (LVA) is one of the surgical treatments of lymphedema. However, only a few reports have evaluated LVA directly. This study aimed to evaluate the patency of LVA using indocyanine green fluorescence lymphography and to determine the optimal anastomosis site in patients with lower extremity lymphedema. Read More

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http://dx.doi.org/10.1016/j.jvsv.2018.10.022DOI Listing
January 2019

Evaluating movement performance: What you see isn't necessarily what you get.

Hum Mov Sci 2019 Jan 16;64:67-74. Epub 2019 Jan 16.

28 Division St, Kingston, Ontario K7L 3N6, Canada. Electronic address:

With the goal of reducing injury and enhancing performance, movement screening tools score an individual's movements against a standard and because it is a predictor of injury symmetry is often included in the score. Movement quality screening tools only consider kinematic asymmetry, which may underestimate the degree of asymmetry present during movement. Consider joint forces: if these forces are atypical, additional stress is created and control is reduced, which can lead to injury if the asymmetry is not addressed. Read More

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http://dx.doi.org/10.1016/j.humov.2019.01.003DOI Listing
January 2019
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Synovial fluid monocyte/macrophage subsets and their correlation to patient-reported outcomes in osteoarthritic patients: a cohort study.

Arthritis Res Ther 2019 Jan 18;21(1):26. Epub 2019 Jan 18.

Arthritis Program, University Health Network, Toronto, ON, Canada.

Background: Chronic, low-grade inflammation of the synovium (synovitis) is a hallmark of osteoarthritis (OA), thus understanding of OA immunobiology, mediated by immune effectors, is of importance. Specifically, monocytes/macrophages (MΦs) are known to be abundantly present in OA joints and involved in OA progression. However, different subsets of OA MΦs have not been investigated in detail, especially in terms of their relationship with patient-reported outcome measures (PROMs). Read More

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http://dx.doi.org/10.1186/s13075-018-1798-2DOI Listing
January 2019

Correlation between Interleukin-17 gene polymorphism and osteoarthritis susceptibility in Han Chinese population.

BMC Med Genet 2019 Jan 18;20(1):20. Epub 2019 Jan 18.

Second Department of Orthopaedic, Central Hospital of Cangzhou City, Cangzhou, 061001, Hebei, China.

Background: Interleukin-17 (IL-17), a pleiotropic cytokine, plays a significant role in the inflammatory diseases. By a pilot study with small population, IL-17 polymorphisms (IL-17A rs2275913 and IL-17F rs763780) showed a more potential risk factor in knee osteoarthritis (OA) in our recruited subjects. In the current study, the association between IL-17A rs2275913 and IL-17F rs763780and the risk of OA in a Chinese population is studied. Read More

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http://dx.doi.org/10.1186/s12881-018-0736-0DOI Listing
January 2019

Multicenter, randomized, double-blind clinical trial to evaluate efficacy and safety of combined glucosamine sulfate and chondroitin sulfate capsules for treating knee osteoarthritis.

Adv Rheumatol 2018 Dec 5;58(1):41. Epub 2018 Dec 5.

Instituto de Pesquisa Clínica e Medicina Avançada (IMA), São Paulo, S.P., Brazil.

Objectives: To compare the efficacy and safety of a new fixed dose combination of glucosamine sulfate and chondroitin sulfate capsules (GS/CS) versus the fixed dose combination of glucosamine hydrochloride and chondroitin sulfate (Cosamin DS®) in capsules in patients with osteoarthritis (OA) of the knee.

Methods: Multicenter, randomized, double-blind study. Participants with knee OA Kellgren-Lawrence grades 1 to 3 and VAS of symptoms ≥4 cm were randomized to receive GS/CS or Cosamin DS® over 12 weeks. Read More

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http://dx.doi.org/10.1186/s42358-018-0041-9DOI Listing
December 2018

The effect of torsional shoe sole stiffness on knee moment and gross efficiency in cycling.

J Sports Sci 2019 Jan 18:1-7. Epub 2019 Jan 18.

a Faculty of Kinesiology , University of Calgary , Calgary , Canada.

Altering torsional stiffness of cycling shoe soles may be a novel approach to reducing knee joint moments and overuse injuries during cycling. We set out to determine if the magnitude of three-dimensional knee moments were different between cycling shoe soles with different torsional stiffnesses. Eight trained male cyclists cycled at 90% lactate threshold power output in one of two cycling shoe conditions in a randomized crossover design. Read More

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https://www.tandfonline.com/doi/full/10.1080/02640414.2019.1
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http://dx.doi.org/10.1080/02640414.2019.1565650DOI Listing
January 2019
1 Read

Selecting and optimising patients for total knee arthroplasty.

Med J Aust 2019 Jan 18. Epub 2019 Jan 18.

South Western Sydney Clinical School, UNSW, Sydney, NSW.

The minimum requirements for total knee arthroplasty (TKA) are significant, prolonged symptoms with supporting clinical and radiological signs. Despite interest in screening tools, there is limited evidence for a specific symptom threshold that justifies surgery. Non-operative treatments including medications, exercise and weight loss are unlikely to reverse radiographic changes, but they may improve symptoms and delay the need for surgery. Read More

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http://dx.doi.org/10.5694/mja2.12109DOI Listing
January 2019

Alterations in Joint Angular Velocity Following Traumatic Knee Injury in Ovine Models.

Ann Biomed Eng 2019 Jan 17. Epub 2019 Jan 17.

McCaig Institute for Bone & Joint Health, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.

Little effort has been directed towards the consequence of an injury on joint angular velocity. We hypothesized that the magnitude of knee joint angular velocity would be decreased after injury. Four injury groups were investigated in an ovine model: (1) anterior cruciate ligament (ACL) and medial collateral ligament (MCL) transection (ACL/MCL Tx) (n = 5), (2) lateral meniscectomy (Mx) (n = 5), (3) partial ACL transection (p-ACL Tx) (n = 5), and (4) partial-ACL and MCL transection (p-ACL/MCL Tx) (n = 5). Read More

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http://dx.doi.org/10.1007/s10439-019-02203-6DOI Listing
January 2019
1 Read

Immunohistochemical examination in arthrofibrosis of the knee joint.

Arch Orthop Trauma Surg 2019 Jan 17. Epub 2019 Jan 17.

Department of Knee, Hip and Shoulder Surgery, Schön Clinik Munich-Harlaching, Academic Teaching Hospital of the Paracelsus Private Medical University Salzburg, Strubergasse 21, 5020, Salzburg, Austria.

Introduction: Arthrofibrosis (AF) is the result of increased cell proliferation and synthesis of matrix proteins (collagen I, III, and VI). Especially after invasive knee surgery, e.g. Read More

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http://link.springer.com/10.1007/s00402-019-03115-9
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http://dx.doi.org/10.1007/s00402-019-03115-9DOI Listing
January 2019
1 Read

Tissue healing following segmental meniscal allograft transplantation: a pilot study.

Knee Surg Sports Traumatol Arthrosc 2019 Jan 17. Epub 2019 Jan 17.

JRF Ortho, Centennial, CO, 80112, USA.

Purpose: This in vivo histological study using an ovine model evaluated the 90-day healing of unilateral segmental meniscal allograft transplantation.

Methods: Fresh-frozen medial menisci were transplanted to replace the right medial meniscus of six female sheep. Tissue healing was evaluated using semi-quantitative, descriptive methods. Read More

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http://link.springer.com/10.1007/s00167-019-05355-z
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http://dx.doi.org/10.1007/s00167-019-05355-zDOI Listing
January 2019
1 Read

ACL degeneration after an excessive increase in the medial proximal tibial angle with medial open wedge high tibial osteotomy.

Knee Surg Sports Traumatol Arthrosc 2019 Jan 17. Epub 2019 Jan 17.

Department of Orthopaedic Surgery, Gifu University Graduate School of Medicine, Yanagido 1-1, Gifu, 501-1194, Japan.

Purpose: This study examined the influence of the mechanical medial proximal tibial angle (MPTA) on anterior cruciate ligament (ACL) degeneration following open wedge high tibial osteotomy (OWHTO). It was hypothesised that an excessive increase in MPTA would be associated with ACL degeneration following OWHTO.

Methods: Seventy-four knees treated with OWHTO were retrospectively examined. Read More

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http://dx.doi.org/10.1007/s00167-019-05354-0DOI Listing
January 2019

[Pediatric injuries of the knee joint].

Authors:
Thomas Neubauer

Unfallchirurg 2019 Jan;122(1)

Unfallchirurgische Abteilung, Landeskrankenhaus Horn, Spitalgasse 10, 3580, Horn, Österreich.

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http://link.springer.com/10.1007/s00113-018-0587-3
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http://dx.doi.org/10.1007/s00113-018-0587-3DOI Listing
January 2019
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Intravenous Tranexamic Acid Versus Topical Aminocaproic Acid: Which Method Has the Least Blood Loss and Transfusion Rates?

J Am Acad Orthop Surg Glob Res Rev 2018 Nov 7;2(11):e072. Epub 2018 Nov 7.

Department of Orthopaedics, Adult Reconstruction Section, University of California: Davis Medical Center, Sacramento, CA.

Introduction: Since the advent of antifibrinolytics, blood transfusions and their associated complications in total joint arthroplasty have decreased. Few studies have compared different antifibrinolytic types with respect to blood loss and transfusion rates. We sought to compare the blood loss and transfusion rates between epsilon-aminocaproic acid (EACA), tranexamic acid (TXA), and control. Read More

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http://dx.doi.org/10.5435/JAAOSGlobal-D-18-00072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324898PMC
November 2018
1 Read

Trends in Inpatient Resource Utilization and Complications Among Total Joint Arthroplasty Recipients: A Retrospective Cohort Study.

J Am Acad Orthop Surg Glob Res Rev 2018 Oct 16;2(10):e058. Epub 2018 Oct 16.

Anesthesiology, Critical Care, and Pain Management (Dr. Yang, Dr. Hong, Dr. Kim, Dr. Memtsoudis, and Dr. Liu), Hospital for Special Surgery, Weill Cornell Medical Center and the Department of Orthopedic Surgery (Dr. Gonzalez Della Valle, and Dr. Ranawat), Hospital for Special Surgery, Weill Cornell Medical Center, New York, NY.

Introduction: Joint arthroplasty practice is highly dynamic to adapt to economic changes and advances in medicine. This study provides updates of the current perioperative practice on healthcare resource utilization.

Methods: The study included total knee arthroplasty, total hip arthroplasty, and total shoulder arthroplasty within the healthcare cost and utilization project New York State database from 2007 to 2013 (ie, 202,100, 127,872, and 8858 cases, respectively). Read More

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http://dx.doi.org/10.5435/JAAOSGlobal-D-18-00058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324886PMC
October 2018

Effects of the applied ancient boxing exercise on leg strength and quality of life in patients with osteoarthritis.

J Exerc Rehabil 2018 Dec 27;14(6):1059-1066. Epub 2018 Dec 27.

Department of Internal Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

This study aimed to investigate the effect of ancient boxing exercise on the strength of leg muscles and quality of life in patients with osteoarthritis. The subjects were divided into 2 groups, control group (CG) and experimental group (EG). The average aged of control and experimental group were 60. Read More

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http://dx.doi.org/10.12965/jer.1836392.196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323346PMC
December 2018

Relations between external moment and movement of the knee joint during the stance phase in patients with severe knee osteoarthritis.

J Orthop 2019 Jan-Feb;16(1):101-104. Epub 2019 Jan 4.

Department of Radiological Sciences, Ibaraki Prefectural University of Health Sciences, Ami, Ibaraki, Japan.

Background: The relations between external knee moment and the knee joint movement during stance phase of the patients with knee osteoarthritis is unknown well. This study try to clarify the relations between external knee moment and the knee joint movement during stance phase of the patients with knee osteoarthritis.

Methods: Subjects comprised 15 patients who had 23 knees with severe osteoarthritis. Read More

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http://dx.doi.org/10.1016/j.jor.2018.12.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329197PMC
January 2019

Septic arthritis of the hip and knee treated surgically in pediatric patients: Analysis of the Kids' Inpatient Database.

J Orthop 2019 Jan-Feb;16(1):97-100. Epub 2019 Jan 4.

Department of Orthopaedic Surgery and Rehabilitation Medicine, SUNY Downstate Medical Center, Brooklyn, NY, USA.

Objective: This study evaluated incidence over time, any association between race and demographics, and hospital-related parameters in pediatric patients with septic hip or knee arthritis.

Methods: The Kids' Inpatient Database was used to identify all children with a diagnosis of septic hip or knee arthritis who underwent incision and drainage (1997-2012).

Results: Between 1997 and 2012, overall incidence of septic arthritis of the knee (0. Read More

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http://dx.doi.org/10.1016/j.jor.2018.12.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329196PMC
January 2019

The role of ADAMTS genes in the end stage of hip osteoarthritis.

Acta Orthop Traumatol Turc 2019 Jan 14. Epub 2019 Jan 14.

Department of Medical Biology, Gazi University Faculty of Medicine, Ankara, Turkey.

Purpose: The aim of this study is to investigate which ADAMTS genes play a major role in the development of primary hip osteoarthritis, by comparing the tissue and blood samples in patients with hip osteoarthritis and a control group.

Material And Methods: Human articular cartilage was obtained from femoral heads of 15 patients with end stage osteoarthritis undergoing total hip replacement. As the control group, the cartilages was obtained from femoral heads of 15 patients, who did not have osteoarthritis or degenerative changes in hip joint, undergoing hip replacement following the fracture of the femoral neck. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1017995X183016
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http://dx.doi.org/10.1016/j.aott.2018.12.007DOI Listing
January 2019
1 Read

The Treadport: Natural Gait on a Treadmill.

Hum Factors 2019 Jan 17:18720818819951. Epub 2019 Jan 17.

University of Utah, Salt Lake City, USA.

Objective:: To evaluate the differences between walking on an advanced robotic locomotion interface called the Treadport and walking overground with healthy subjects.

Background:: Previous studies have compared treadmill-based and overground walking in terms of gait parameters. The Treadport's unique features including self-selected speed capability, large belt, kinesthetic force feedback, and virtual reality environment distinguish it from other locomotion interfaces and could provide a natural walking experience for the users. Read More

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http://dx.doi.org/10.1177/0018720818819951DOI Listing
January 2019
2 Reads

Suspected Compartment Syndrome, Consumptive Thrombocytopenia, and Anemia Secondary to a Ruptured Arterial Aneurysm or Pseudoaneurysm Following Multiple Stifle Surgeries.

J Am Anim Hosp Assoc 2019 Jan 17. Epub 2019 Jan 17.

From Friendship Hospital for Animals, Washington, District of Columbia (M.L., J.M.C., S.K.H.); and Veterinary Pathology Services, Joint Pathology Center, Silver Spring, Maryland (J.R.C.).

A 12 yr old male neutered beagle was presented on transfer to the intensive care unit with severe anemia, thrombocytopenia, and bruising detected 1 day after undergoing tibial plateau leveling osteotomy surgery. The patient had undergone extra-capsular stifle stabilization surgery 14 wk prior to treat ligament disease in the same knee. Laboratory testing and treatment for anemia, presumptive immune-mediated thrombocytopenia, and possible hemostatic disorder was initiated. Read More

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http://dx.doi.org/10.5326/JAAHA-MS-6659DOI Listing
January 2019

The efficacy of local liposomal bupivacaine infiltration on pain and recovery after Total Joint Arthroplasty: A systematic review and meta-analysis of randomized controlled trials.

Medicine (Baltimore) 2019 Jan;98(3):e14092

Trauma knee department 1, Tianjin Hospital, Tianjin.

Background: Total Joint Arthroplasty (TJA) is gradually emerging as the treatment of choice for end-stage osteoarthritis. In the past, Perioperative liposomal bupivacaine treatment is still a controversial subject in TJA. Therefore, we write this systematic review and meta-analysis to evaluate the efficacy of liposomal bupivacaine on pain and recovery after TJA. Read More

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http://dx.doi.org/10.1097/MD.0000000000014092DOI Listing
January 2019
1 Read

Nomenclature Inconsistency and Selective Outcome Reporting Hinder Understanding of Stem Cell Therapy for the Knee.

J Bone Joint Surg Am 2019 Jan;101(2):186-195

Department of Orthopaedic Surgery, Keck School of Medicine of USC, Los Angeles, California.

Background: The prospect of treating knee cartilage injury/pathology with mesenchymal stem cells (MSCs) has garnered considerable attention in recent years, but study heterogeneity and a lack of randomized controlled trials (RCTs) preclude quantitative analysis. The purpose of this review was to provide clinicians with an overview of RCTs that addresses 2 key areas that have been largely overlooked: nomenclature inconsistency and selective outcome reporting.

Methods: RCTs that purported to use stem cells or MSCs to treat knee cartilage were identified with use of PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses). Read More

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http://dx.doi.org/10.2106/JBJS.17.01474DOI Listing
January 2019

A Surgeon Scorecard Is Associated with Improved Value in Elective Primary Hip and Knee Arthroplasty.

J Bone Joint Surg Am 2019 Jan;101(2):152-159

Department of Surgery and Perioperative Care, Dell Medical School at the University of Texas, Austin, Texas.

Background: Despite increasing interest in total joint arthroplasty registries, evidence of the impact of physician-level performance on the value of care provided to patients undergoing hip and knee arthroplasty is lacking. The purpose of this study was to examine the effectiveness of an unblinded orthopaedic surgeon-specific value scorecard in improving patient outcomes and reducing hospital costs.

Methods: We retrospectively analyzed patient outcomes and hospital costs associated with total joint arthroplasties before and 9 months after the introduction of a Surgeon Value Scorecard at an urban tertiary care center. Read More

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http://dx.doi.org/10.2106/JBJS.17.01553DOI Listing
January 2019

A Novel, Automated Text-Messaging System Is Effective in Patients Undergoing Total Joint Arthroplasty.

J Bone Joint Surg Am 2019 Jan;101(2):145-151

Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois.

Background: Digital patient engagement platforms are designed to improve the efficacy of the perioperative surgical home, but the currently available solutions have shown low patient and provider adoption. The purpose of this study was to evaluate the effectiveness of a text-messaging (Short Message Service [SMS]) bot with respect to patient engagement following joint replacement procedures in a randomized clinical trial.

Methods: One hundred and fifty-nine patients (83 patients in the control group and 76 patients in the intervention group) were enrolled in a randomized controlled trial comparing the effectiveness of an SMS bot (intervention group) with the traditional perioperative education process (control group) in patients undergoing primary total knee or hip arthroplasty. Read More

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http://dx.doi.org/10.2106/JBJS.17.01505DOI Listing
January 2019

Comparison of Infection Risk with Corticosteroid or Hyaluronic Acid Injection Prior to Total Knee Arthroplasty.

J Bone Joint Surg Am 2019 Jan;101(2):112-118

Hospital for Special Surgery, New York, NY.

Background: Recent studies have shown that intra-articular injections ≤3 months before total knee arthroplasty increase the risk of periprosthetic joint infection. We are aware of no previous study that has differentiated the risk of periprosthetic joint infection on the basis of the type of medication injected. In addition, we are aware of no prior study that has evaluated whether hyaluronic acid injections increase the risk of infection after total knee arthroplasty. Read More

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http://dx.doi.org/10.2106/JBJS.18.00454DOI Listing
January 2019
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What's New in Adult Reconstructive Knee Surgery.

J Bone Joint Surg Am 2019 Jan;101(2):103-111

Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.2106/JBJS.18.01157DOI Listing
January 2019
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Functional outcome of two-stage reimplantation in patients with periprosthetic joint infection after primary total knee arthroplasty.

Int Orthop 2019 Jan 16. Epub 2019 Jan 16.

Russian Scientific Research Institute of Traumatology and Orthopedics named after R.R. Vreden, Akademika Baykova St., 8, St. Petersburg, 195427, Russian Federation.

Introduction: Two-stage reimplantation in patients with chronic periprosthetic joint infection (PJI) after total knee arthroplasty (TKA) with the use of either articulating or static antibiotic-loaded spacers during the first step is considered to be the golden standard in orthopaedics.

The Aim Of The Study: The aim of the study was to evaluate the correlation of spacer type with the infection elimination rate as well as functional outcomes after two-staged revision TKA in patients with PJI.

Materials And Methods: The cohort comprised 161 patients who were treated for PJI after TKA during a period from January 2007 to December 2015. Read More

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http://link.springer.com/10.1007/s00264-019-04296-z
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http://dx.doi.org/10.1007/s00264-019-04296-zDOI Listing
January 2019
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The Diagnosis and Therapy of Degenerative Knee Joint Disease: Expert Consensus from the Chinese Pain Medicine Panel.

Pain Res Manag 2018 13;2018:2010129. Epub 2018 Dec 13.

The Second Affiliated Hospital of Harbin Medical University, Harbin, China.

At present, there are many constantly updated guidelines and consensuses on the diagnosis and treatment of osteoarthritis both at home and abroad. The recommendations established using methods of evidence-based medicine has experienced strict research on controlling bias and promoting reproduction rate. As a result, the previous evidence was reevaluated, and a lot of changes were provoked in the diagnosis and treatment concept of osteoarthritis. Read More

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https://www.hindawi.com/journals/prm/2018/2010129/
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http://dx.doi.org/10.1155/2018/2010129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311766PMC
December 2018
1 Read

Micro-scale assessment of the postoperative effect of anterior cruciate ligament reconstruction preclinical study using a 7.1T micro-magnetic resonance imaging.

Exp Ther Med 2019 Jan 19;17(1):214-220. Epub 2018 Apr 19.

Department of Sports Medicine and Arthroscopic Surgery, Huashan Hospital, Sports Medicine Center, Fudan University, Shanghai 200040, P.R. China.

High-field micro-magnetic resonance imaging (MRI) scanning may provide additional information for quantitative analysis of graft bone healing processes, thus serving as a promising supplementary method in graft and bone healing evaluation following anterior cruciate ligament reconstruction (ACLR) surgery during preclinical studies. The present study included 12 New Zealand white rabbits that underwent ACLR with polyethylene terephthalate (PET) ligament. At 4, 8, and 16 weeks following surgery, 4 rabbits were euthanized and knee joint samples were harvested for a 7. Read More

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http://www.spandidos-publications.com/10.3892/etm.2018.6080
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http://dx.doi.org/10.3892/etm.2018.6080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307410PMC
January 2019
1 Read

Human amniotic membrane intra-articular injection prevents cartilage damage in an osteoarthritis model.

Exp Ther Med 2019 Jan 2;17(1):11-16. Epub 2018 Nov 2.

Orthopedics and Traumatology Service, Hospital Universitario 'Dr. José E. González', Monterrey, NL 64460, Mexico.

Osteoarthritis (OA) is a degenerative joint disease that affects the soft tissues and bones of involved articulations as a result of deregulation between synthesis and extracellular matrix degradation in articular cartilage. The present study evaluated the effect of intra-articular injection of human amniotic membrane (AM) as a treatment in an OA animal model in the knee. Chemical OA was developed in the knees of New Zealand rabbits. Read More

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http://dx.doi.org/10.3892/etm.2018.6924DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307525PMC
January 2019

Gait oscillation analysis during gait and stair-stepping in elder patients with knee osteoarthritis.

J Orthop Surg Res 2019 Jan 16;14(1):21. Epub 2019 Jan 16.

Department of Orthopaedic Surgery, National Hospital Organization Kanmon Medical Center, 1-1 Choufusotoura Shimonoseki, Yamaguchi, 752-8510, Japan.

Background: Evaluation of knee and lower limb function alone is not sufficient to assess gait. For accurate assessment of gait abnormality, gait oscillation should also be measured. The goal of this analysis was to assess the influence of the knee joint on gait oscillation during gait and stair-stepping in patients with osteoarthritis of the knee. Read More

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http://dx.doi.org/10.1186/s13018-019-1064-6DOI Listing
January 2019

Directional atherectomy with anti-restenotic therapy for the treatment of no-stenting zones.

J Cardiovasc Surg (Torino) 2019 Jan 16. Epub 2019 Jan 16.

Groupe Cardiovasculaire Interventionnel Clinique Pasteur Toulouse, Clinique Pasteur Gcvi, Toulouse, France.

Endovascular treatment for peripheral artery occlusive disease carries unresolved problem of restenosis. Treatment modalities in areas of high mechanical stress like popliteal artery and common femoral artery remains challenging. New-generation devices improved the results of stent therapy in this anatomical territory, but could impact on future surgical options if they are needed. Read More

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https://www.minervamedica.it/index2.php?show=R37Y9999N00A190
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http://dx.doi.org/10.23736/S0021-9509.19.10866-XDOI Listing
January 2019
1 Read

The Effect of Dexamethasone, Adrenergic and Cholinergic Receptor Agonists on Phospholipid Metabolism in Human Osteoarthritic Synoviocytes.

Int J Mol Sci 2019 Jan 15;20(2). Epub 2019 Jan 15.

Laboratory for Experimental Orthopaedics, Department of Orthopaedics, Justus Liebig University Giessen, 35392 Giessen, Germany.

Phospholipids (PLs) possess the unique ability to contribute to synovial joint lubrication. The aim of our study was to determine for the first time the effect of dexamethasone and some adrenergic and cholinergic agonists on the biosynthesis and release of PLs from human fibroblast-like synoviocytes (FLS). Osteoarthritic human knee FLS were treated with dexamethasone, terbutaline, epinephrine, carbachol, and pilocarpine, or the glucocorticoid receptor antagonist RU 486. Read More

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http://dx.doi.org/10.3390/ijms20020342DOI Listing
January 2019

Residual Mild Varus Alignment and Neutral Mechanical Alignment Have Similar Outcome after Total Knee Arthroplasty for Varus Osteoarthritis in Five-Year Follow-Up.

J Knee Surg 2019 Jan 16. Epub 2019 Jan 16.

Department of Joint Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.

The effect of residual varus on survival rate and function in patients with varus knee osteoarthritis (OA) was considered an important issue for successful primary total knee arthroplasty (TKA). In this study, we compared the midterm clinical and functional outcomes in patients with different residual varus. A retrospective review of 175 patients (219 knees) with varus OA was > 3° for the hip-knee-ankle (HKA) who underwent primary TKA after exclusions and loss to follow-up from 237 patients (281 knees). Read More

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http://dx.doi.org/10.1055/s-0038-1677497DOI Listing
January 2019

Effectiveness and safety of tranexamic acid in total joint arthroplasty.

J Perioper Pract 2019 Jan 16:1750458919825812. Epub 2019 Jan 16.

1 Division of Trauma & Orthopaedics Surgery Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.

Total Joint arthroplasty is associated with significant blood loss, which could necessitate the use of blood transfusion. Several techniques are being utilised to limit the volume of blood loss, in order to avoid transfusion. In this review, we look at blood loss in total joint arthroplasty, and the perioperative strategies to limit the loss of blood. Read More

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http://dx.doi.org/10.1177/1750458919825812DOI Listing
January 2019

Posterior-stabilized versus cruciate-retained implants for total knee arthroplasty: a meta-analysis of clinical trials.

Eur J Orthop Surg Traumatol 2019 Jan 16. Epub 2019 Jan 16.

Department of Orthopaedics, RWTH Aachen University Clinic, Pauwelsstraße 30, 52074, Aachen, Germany.

Aim: A meta-analysis comparing the outcomes of patients undergoing cruciate retaining (CR) versus posterior stabilized (PS) in primary total knee arthroplasty was performed. The outcomes of interest were the Knee Society Rating System, clinical (KSCS) and functional (KSFS) subscales, joint range of motion (ROM), surgical duration and further complications (anterior knee pain, instability and revision rate).

Materials And Methods: The search was conducted in July 2018, accessing the following databases: Cochrane Systematic Reviews, Scopus, PubMed, EMBASE, CINAHL, AMED and Google Scholar. Read More

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http://link.springer.com/10.1007/s00590-019-02370-1
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http://dx.doi.org/10.1007/s00590-019-02370-1DOI Listing
January 2019
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Short-term pain reduction after low-dose radiotherapy in patients with severe osteoarthritis of the hip or knee joint: a cohort study and literature review.

Eur J Orthop Surg Traumatol 2019 Jan 16. Epub 2019 Jan 16.

Zuyderland Medical Centre, Sittard-Geleen, The Netherlands.

Background: Low-dose radiotherapy (LDRT) for pain reduction in osteoarthritis (OA) is a frequently used treatment in Germany and Eastern European countries. The evidence on the effects of LDRT on pain in patients with OA remains unclear. This study evaluated the effect of LDRT on pain in patients with severe OA of the hip or knee joint. Read More

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http://link.springer.com/10.1007/s00590-019-02377-8
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http://dx.doi.org/10.1007/s00590-019-02377-8DOI Listing
January 2019
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Dynamic intraligamentary stabilization of anterior cruciate ligament repair: hardware removal has no effect on knee laxity at 2-year follow-up.

Arch Orthop Trauma Surg 2019 Jan 16. Epub 2019 Jan 16.

Sonnenhof Orthopaedic Center, Buchserstrasse 30, 3006, Bern, Switzerland.

Introduction: Dynamic intraligamentary stabilization (DIS) stabilizes the knee joint during anterior cruciate ligament (ACL) healing. After 6 months, tibial hardware removal is offered to the patients if local discomfort at the implant site is present.

Aim: This study compared knee laxity and functional scores 2 years after DIS between patients with and without hardware removal. Read More

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http://dx.doi.org/10.1007/s00402-019-03113-xDOI Listing
January 2019

Impact of TNF inhibitor therapy on joint replacement rates in rheumatoid arthritis: a matched cohort analysis of BSRBR-RA UK registry data.

Rheumatology (Oxford) 2019 Jan 10. Epub 2019 Jan 10.

Pharmaco- and Device-Epidemiology Group, Centre for Statistics in Medicine, NDORMS, University of Oxford, Oxford.

Objectives: Previous ecological data suggest a decline in the need for joint replacements in RA patients following the introduction of TNF inhibitor (TNFi) therapy, although patient-level data are lacking. Our primary aim was to estimate the association between TNFi use and subsequent incidence of total hip replacement (THR) and total knee replacement.

Methods: A propensity score matched cohort was analysed using the British Society for Rheumatology Biologics Registry (2001-2016) for RA data. Read More

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https://academic.oup.com/rheumatology/advance-article/doi/10
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http://dx.doi.org/10.1093/rheumatology/key424DOI Listing
January 2019
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Opioid-Induced Reductions in Gait Variability in Healthy Volunteers and Individuals with Knee Osteoarthritis.

Pain Med 2019 Jan 12. Epub 2019 Jan 12.

The Parker Institute, Copenhagen University Hospital Bispebjerg-Frederiksberg, Copenhagen, Denmark.

Objective: To investigate differences in gait variability induced by two different single-dose opioid formulations and an inert placebo in healthy volunteers and knee osteoarthritis patients.

Design: Experimental, randomized, double-blinded, crossover study of inert placebo (calcium tablets), 50 mg of tapentadol, and 100 mg of tramadol.

Setting: Laboratory setting. Read More

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http://dx.doi.org/10.1093/pm/pny286DOI Listing
January 2019
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The Popliteal Keystone Island Flap for Management of Contracture around Knee Joint: A Report of Two Cases.

Authors:
Mahmoud A Hifny

J Burn Care Res 2019 Jan 14. Epub 2019 Jan 14.

Department of Plastic Surgery, Faculty of Medicine, Qena University Hospital, South Valley University, Egypt.

Introduction: Flexion contracture affecting the knee joint is considered a challenging obstacle which usually affects patients' quality of life with significant functional disability. Several surgical procedures have been described for proper closure of surgical defects following contracture release over popliteal fossa. Although keystone flap reported for closure of full thickness burns defects, to our knowledge, it has never been used previously in management of hypertrophic scar contracture around the knee joint. Read More

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http://dx.doi.org/10.1093/jbcr/irz011DOI Listing
January 2019

Bleed volume of experimental knee haemarthrosis correlates with the subsequent degree of haemophilic arthropathy.

Haemophilia 2019 Jan 16. Epub 2019 Jan 16.

Global Drug Discovery, Novo Nordisk A/S, Maaloev, Denmark.

Background: Haemophilic arthropathy is the main morbidity of haemophilia. The individual pathological response to the same number of clinically evident joint bleeds is highly variable; thus, it remains unknown if certain joint bleeding characteristics are critical for the development of arthropathy.

Aim: To study the relation between bleed volume and subsequent development of arthropathy, we aimed to develop quantitative in vivo imaging of active joint bleeds in a mouse model of haemophilia. Read More

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http://doi.wiley.com/10.1111/hae.13672
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http://dx.doi.org/10.1111/hae.13672DOI Listing
January 2019
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Effects of Viscosupplementation on Knee Joint Arthrokinematics - Pilot Study.

Ortop Traumatol Rehabil 2018 Oct;20(5):409-419

Politechnika Opolska, Wydział Wychowania Fizycznego i Fizjoterapii, Opole, Polska / Opole University of Technology, Faculty of Physical Education and Physiotherapy, Opole, Poland.

Background: Osteoarthritis is one of the most common dysfunctions of the musculoskeletal system and viscosup-plementation is becoming an increasingly popular treatment in OA. However, current knowledge regarding biomechanical changes in synovial joints reveals many discrepancies. Therefore, the aim of our study was to evaluate the effect of visco-supplementation on knee joint arthrokinematics as analyzed by vibroarthrography. Read More

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https://ortopedia.com.pl/gicid/01.3001.0012.8277
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http://dx.doi.org/10.5604/01.3001.0012.8277DOI Listing
October 2018
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Practical Aspects of Hyaluronic Acid Application in Biolevox HA Preparations - Report on Research.

Ortop Traumatol Rehabil 2018 Oct;20(5):431-435

Wyższa Szkoła Biznesu i Nauk o Zdrowiu w Łodzi, Polska / The Academy of Business and Health Sciences of Lodz, Poland.

HA preparations in intraarticular injections have been applied in medicine since 1986 and became widely used in Poland at the beginning of the 90s of the twentieth century. Since then, numerous cases of successful application of intra-articular injections (the so called viscosupplementation) have been described in Polish and foreign literature. Changes in the molecular mass of hyaluronic acid and the related specific spatial structure result in different metabolic and immunological properties. Read More

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https://ortopedia.com.pl/gicid/01.3001.0012.7474
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http://dx.doi.org/10.5604/01.3001.0012.7474DOI Listing
October 2018
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Difficulties in Treating Complex Knee Injuries with Fracture of Posterior Tibial Plateau.

Ortop Traumatol Rehabil 2018 Aug;20(4):293-300

Samodzielny Publiczny Szpital Kliniczny CMKP im. prof. A. Grucy, Otwock, Polska / Gruca Orthopaedic and Trauma Teaching Hospita, Centre of Postgraduate Medical Education in Otwock, Poland Klinika Chirurgii Urazowej Narządu Ruchu i Ortopedii / Department of Traumatology and Orthopaedics.

Background: The aim of the study was to assess the outcomes of surgical treatment of complex knee injuries with a posterior inverted-L approach to the knee joint.

Material And Methods: The study retrospectively enrolled 13 patients who underwent surgical treatment due to knee injuries with posterior tibial plateau fractures in 2015-2017. Pre-operative planning was based on antero-po-sterior and lateral X-rays and CT images. Read More

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https://ortopedia.com.pl/gicid/01.3001.0012.6463
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http://dx.doi.org/10.5604/01.3001.0012.6463DOI Listing
August 2018
1 Read