35,040 results match your criteria Kidney Transplantation Surgical Complications


Various Techniques and Outcomes of Arterial Anastomosis in Live Renal Transplant: An Institutional Experience.

Cureus 2022 May 23;14(5):e25262. Epub 2022 May 23.

Urology, Madras Medical College, Chennai, IND.

Introduction Renal transplantation with multiple arteries is associated with a major index of surgical complications. Relevant papers and meta-analyses have shown relatively more vascular and urological complications in transplant of donor kidneys with multiple arteries. In live donor grafts due to the unavailability of a carrel patch, several techniques for bench and in situ reconstruction have been described in order to reduce the incidence of these vascular complications. Read More

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PO 21% oxygenated hypothermic machine perfusion in kidney transplantation: Any clinical benefit?

Int J Artif Organs 2022 Jun 24:3913988221107946. Epub 2022 Jun 24.

Liver-Kidney Transplantation Unit, Department of Medicine, University of Udine, Udine, Italy.

Background: In deceased donor kidney transplantation (KT), the use of hypothermic machine perfusion (HMP) has been acquiring the status of best practice in the pre-transplant management of kidney grafts. Two types of HMP are currently available, oxygenated HMP and non-oxygenated HMP. However, data on the real clinical impact of oxygenation on KT outcome are still heterogeneous. Read More

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Robotic Radical Prostatectomy for Prostate Cancer in Renal Transplant Recipients: Results from a Multicenter Series.

Eur Urol 2022 Jun 21. Epub 2022 Jun 21.

Department of Surgical Sciences, University of Turin and Città della Salute e della Scienza, Turin, Italy.

Background: Despite an expected increase in prostate cancer (PCa) incidence in the renal transplant recipient (RTR) population in the near future, robot-assisted radical prostatectomy (RARP) in these patients has been poorly detailed. It is not well understood whether results are comparable to RARP in the non-RTR setting.

Objective: To describe the surgical technique for RARP in RTR and report results from our multi-institutional experience. Read More

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Analysis of Volatile Anesthetic-Induced Organ Protection in Simultaneous Pancreas-Kidney Transplantation.

J Clin Med 2022 Jun 13;11(12). Epub 2022 Jun 13.

Department of Visceral, Transplantation, Vascular and Thoracic Surgery, University Hospital of Leipzig, 04103 Leipzig, Germany.

Background: Despite recent advances in surgical procedures and immunosuppressive regimes, early pancreatic graft dysfunction, mainly specified as ischemia-reperfusion injury (IRI)-Remains a common cause of pancreas graft failure with potentially worse outcomes in simultaneous pancreas-kidney transplantation (SPKT). Anesthetic conditioning is a widely described strategy to attenuate IRI and facilitate graft protection. Here, we investigate the effects of different volatile anesthetics (VAs) on early IRI-associated posttransplant clinical outcomes as well as graft function and outcome in SPKT recipients. Read More

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A Case Report of Tolvaptan Therapy for ADPKD Patients With COVID-19. The Need for Appropriate Counselling for Temporary Drug Discontinuation.

In Vivo 2022 Jul-Aug;36(4):1994-1997

Nephrology, Dialysis and Kidney Transplantation Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy;

Background: Patients with autosomal dominant polycystic kidney disease (ADPKD) may require specific therapy with vasopressin receptor antagonists to slow the progression of renal disease. Because of its mechanism of action, the most common side effects are polyuria, nocturia, and polydipsia. Elevations of liver enzyme levels can also occur during treatment with Tolvaptan. Read More

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Early Light Chains Removal and Albumin Levels with a Double Filter-Based Extracorporeal Treatment for Acute Myeloma Kidney.

Toxins (Basel) 2022 Jun 5;14(6). Epub 2022 Jun 5.

Nephrology Dialysis and Renal Transplantation Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Department of Experimental Diagnostic and Specialty Medicine (DIMES), Alma Mater Studiorum University of Bologna, 40138 Bologna, Italy.

Renal impairment in Multiple Myeloma (MM) represents one of the most important factors that influences patient survival. In fact, before the introduction of modern chemotherapy, less than 25% of patients with acute kidney injury (AKI) and MM who required dialysis recovered sufficient renal function to become independent from dialysis, with a median overall survival of less than 1 year. There are many other factors involved in determining patient survival. Read More

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Vitamin D Metabolites, Body Composition, and Nutritional Status in Patients in the Long Term After Kidney Transplantation.

Ann Transplant 2022 Jun 21;27:e936009. Epub 2022 Jun 21.

Department of Internal Medicine and Transplant Nephrology, Chair of Pulmonology, Rheumatology and Clinical Immunology, Medical University of Łódź, Łódź, Poland.

BACKGROUND The aim of the study was to assess the relationship between body composition and nutritional status with the level of vitamin D metabolites 25(OH)D and 1,25(OH)₂D in patients in the long term after kidney transplantation (KTx). MATERIAL AND METHODS During 2 routine outpatient visits in summer and winter, the anthropometric and body composition measurements and laboratory data from 105 stable KTx patients were taken and the annual averages were analyzed. RESULTS Data of 64 patients (26 F, 38 M) at mean age 49. Read More

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Overview of pediatric kidney transplantation.

Semin Pediatr Surg 2022 Jun 29;31(3):151194. Epub 2022 May 29.

Division of Transplantation and Advanced Hepatobiliary Surgery, Ann and Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, IL, United States. Electronic address:

Kidney transplantation is the treatment of choice for pediatric patients with end-stage kidney disease. Unlike adult recipients undergoing transplantation, special considerations must be taken when transplanting children based on the underlying etiology of kidney disease, previous surgical procedures, anatomical limitations and necessary technical adjustments. Additionally, the choice of donor must be measured to ensure optimal graft survival given a longer post-transplant life expectancy. Read More

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The Perspectives of Biomarkers in Predicting the Survival of the Renal Graft.

Front Pediatr 2022 3;10:869628. Epub 2022 Jun 3.

Department of Surgical Sciences, Discipline of Urology, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.

Kidney transplantation (KT) is currently the elective approach for patients with end-stage renal disease. Although it is a safe choice for these patients, the early complications can lead to graft dysfunction. One of the most redoubtable complications is delayed graft function (DGF), having no specific treatment. Read More

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Could thymoglobulin increase hemorrhagic risk in the perioperative transplantation period of sensitized kidney recipients?

Actas Urol Esp (Engl Ed) 2022 Jun 15. Epub 2022 Jun 15.

Servicio Urología, Hospital del Mar, Barcelona, Spain.

Objective: It has been described that thymoglobulin could increase the risk of infections and malignancies, in comparison to basiliximab. Leukopenia and thrombocytopenia are also more common within the first days after transplantation among thymoglobulin patients. Our objective was to analyze bleeding complications in this subset of patients. Read More

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Elevated parathyroid hormone one year after kidney transplantation is an independent risk factor for graft loss even without hypercalcemia.

BMC Nephrol 2022 Jun 17;23(1):212. Epub 2022 Jun 17.

Department of Transplant and Endocrine Surgery, Japanese Red Cross Nagoya Daini Hospital, 2-9 Myoken-cho, Showa-ku, Nagoya, Aichi, 4668650, Japan.

Background: Hypercalcemic hyperparathyroidism has been associated with poor outcomes after kidney transplantation (KTx). However, the clinical implications of normocalcemic hyperparathyroidism after KTx are unclear. This retrospective cohort study attempted to identify these implications. Read More

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Phosphate balance during dialysis and after kidney transplantation in patients with chronic kidney disease.

Curr Opin Nephrol Hypertens 2022 Jul 10;31(4):326-331. Epub 2022 Jun 10.

Laboratorio de Fisiopatologia Renal LIM16, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo.

Purpose Of Review: In patients with chronic kidney disease (CKD), hyperphosphatemia is associated with several adverse outcomes, including bone fragility and progression of kidney and cardiovascular disease. However, there is a knowledge gap regarding phosphate balance in CKD. This review explores its current state, depending on the stage of CKD, dialysis modalities, and the influence of kidney transplantation. Read More

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The effect of single or multiple arteries in the donor kidney on renal transplant surgical outcomes.

Ir J Med Sci 2022 Jun 13. Epub 2022 Jun 13.

Department of Urology, University of Health Sciences Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey.

Background: As the number of end-stage renal disease (ESRD) patients is increasing, but there are not enough living donors, it is necessary to broaden the criteria for candidates who can undergo donor nephrectomy. Thanks to surgeons' increasing experience with laparoscopic donor nephrectomy (LND), multiple renal artery grafts, previously considered a relative contraindication to donor nephrectomy, have become candidates for LDN. We aimed to compare the outcomes of donors and recipients with single artery and with multiple arteries in LDN. Read More

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Gut Microbiota Dysbiosis in BK Polyomavirus-Infected Renal Transplant Recipients: A Case-Control Study.

Front Cell Infect Microbiol 2022 27;12:860201. Epub 2022 May 27.

Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

Background: BK polyomavirus infection results in renal allograft dysfunction, and it is important to find methods of prediction and treatment. As a regulator of host immunity, changes in the gut microbiota are associated with a variety of infections. However, the correlation between microbiota dysbiosis and posttransplant BK polyomavirus infection was rarely studied. Read More

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Incidentally found focal xanthogranulomatous pyelonephritis with extensive venous thrombus.

Can J Urol 2022 Jun;29(3):11187-11189

Section of Urology and Renal Transplantation, Virginia Mason Franciscan Health, Seattle, Washington, USA.

A 71-year-old woman with history of asthma presented with 2 months history of shortness of breath; on imaging an incidental left renal mass was noted. Subsequent renal protocol CT was obtained that showed a 4.5 cm left upper pole exophytic mass with renal vein thrombus extending into the inferior vena cava to the level of the caudate lobe concerning for renal cell carcinoma. Read More

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Molecular Detection and Glycoprotein B (UL55) Genotyping of Cytomegalovirus among Sudanese Renal Transplant Recipients.

Biomed Res Int 2022 31;2022:5403694. Epub 2022 May 31.

Department of Microbiology, Faculty of Medical Laboratory Science, Al Neelain University, Sudan.

Background: Cytomegalovirus (CMV) is the most common opportunistic pathogen among renal transplants with significant morbidity and mortality. This study was designed to detect CMV DNA and to determine the frequency of different glycoprotein B (UL55) genotypes among Sudanese renal transplant recipients.

Methods: One hundred and four renal transplant recipients were included in this study. Read More

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Comparison of Open and Robot-Assisted Kidney Transplantation in terms of Perioperative and Postoperative Outcomes.

Int J Clin Pract 2022 6;2022:2663108. Epub 2022 May 6.

Department of Urology, Bahçelievler Memorial Hospital, Istanbul, Turkey.

Background: The gold standard treatment method for end-stage renal disease (ESRD) is renal transplantation (RT). RT can be done with open or minimally invasive surgical methods. We aimed to compare the outcomes between patients who underwent robot-assisted renal transplantation (RART) and open renal transplantation (ORT). Read More

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Incidence and Determinants of Complications of Percutaneous Kidney Biopsy in a Large Cohort of Native Kidney and Kidney Transplant Recipients.

Sultan Qaboos Univ Med J 2022 May 26;22(2):268-273. Epub 2022 May 26.

Department of Internal Medicine, Kasr Alainy University Hospital, Cairo, Egypt.

Objectives: This study aimed to determine the incidence and factors associated with complications for kidney biopsy. Percutaneous kidney biopsy is a useful diagnostic procedure. Haemorrhagic complications may occur following the procedure. Read More

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The Assessment and Outcomes of Crossmatching in Lung Transplantation in Korean Patients.

J Korean Med Sci 2022 Jun 6;37(22):e177. Epub 2022 Jun 6.

Department of Thoracic and Cardiovascular Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

Background: In lung transplantation, human leukocyte antigen (HLA) compatibility is not included in the lung allocation score system or considered when placing donor allografts. However, HLA matching may affect the outcomes of lung transplantation. This study evaluated the current assessment status, prevalence, and effects of HLA crossmatching in lung transplantation in Korean patients using nationwide multicenter registry data. Read More

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Zoster paresis in a renal transplant patient: preliminary considerations.

BMJ Case Rep 2022 06 6;15(6). Epub 2022 Jun 6.

Department of Dermatology, Indiana University School of Medicine, Indianapolis, Indiana, USA

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Simultaneous nephrectomy during kidney transplantation for polycystic kidney disease does not detrimentally impact comorbidity and graft survival.

World J Transplant 2022 May;12(5):100-111

Surgical and Abdominal Transplantation Unit, University Clinics Saint Luc, Brussels 1200, Belgium.

Background: The lack of space, as an indication for a native unilateral nephrectomy for positioning a future kidney graft in the absence of other autosomal dominant polycystic kidney disease-related symptoms, remains controversial.

Aim: To evaluate the surgical comorbidity and the impact on graft survival of an associated ipsilateral native nephrectomy during isolated kidney transplantation in patients with autosomal dominant polycystic kidney disease.

Methods: One hundred and fifty-four kidney transplantations performed between January 2007 and January 2019 of which 77 without (kidney transplant alone (KTA) group) and 77 with associated ipsilateral nephrectomy (KTIN group), were retrospectively reviewed. Read More

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Chronic kidney disease and vaccinations-A practical guide for primary care providers.

J Natl Med Assoc 2022 Jun 31;114(3S2):S20-S24. Epub 2022 May 31.

Division of Nephrology and Hypertension, University of Kansas Medical Center Kansas City, Kansas, KS, USA.

Patients with chronic kidney disease (CKD) are susceptible to infectious organisms in part due to the many facets of uremia-associated immune deficiency. Vaccination plays a crucial role in curbing vaccine preventable infection in patients with CKD and Kidney transplant recipients. Vaccination should be done early in the course of CKD or prior to kidney transplantation when possible. Read More

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Predicting major events in ambulatory patients with advanced heart failure awaiting heart transplantation: a pilot study.

J Cardiovasc Med (Hagerstown) 2022 Jun;23(6):387-393

Cardiology Unit, Department of Cardiology and Medicine, Ospedali dei Colli Monaldi-Cotugno-CTO & University of Campania 'Luigi Vanvitelli'.

Aims: In heart failure (HF), prognostic risk scores focus on all-cause mortality prediction. However, in advanced HF (AdHF) ambulatory patients awaiting heart transplantation (HTx), hospitalizations for acutely decompensated/worsening HF are relevant to clinical decision-making, but unpredicted by common risk functions.

Methods: Among consecutive ambulatory patients added to the waitlist for HTx, event discriminators within 2 years from recruitment were assessed prospectively by area under the curve from receiver-operating characteristic curves, and by Cox proportional hazards models. Read More

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Preemptive simultaneous pancreas kidney transplantation has survival benefit to patients.

Kidney Int 2022 May 27. Epub 2022 May 27.

Nephrology and Kidney Transplant Department, Hospital Clínic de Barcelona, Barcelona, Spain; Laboratori Experimental de Nefrologia I Trasplantament (LENIT), Fundació Clínic per a la Recerca Biomèdica (FCRB), Barcelona, Spain. Electronic address:

Several organ allocation protocols give priority to wait-listed simultaneous kidney-pancreas (SPK) transplant recipients to mitigate the higher cardiovascular risk of patients with diabetes mellitus on dialysis. The available information regarding the impact of preemptive simultaneous kidney-pancreas transplantation on recipient and graft outcomes is nonetheless controversial. To help resolve this, we explored the influence of preemptive simultaneous kidney-pancreas transplants on patient and graft survival through a retrospective analysis of the OPTN/UNOS database, encompassing 9690 simultaneous transplant recipients between 2000 and 2017. Read More

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KIDNEY DAMAGE IN PATIENTS AFTER ALLOGENEIC STEM CELL TRANSPLANTATION.

Wiad Lek 2022 ;75(4 pt 1):877-880

WARSAW MEDICAL UNIVERSITY, WARSAW, POLAND.

The aim of the review is to present the most common renal complications after HSCT such as acute kidney injury, chronic kidney disease glomerulopathies. HSCT is a critical therapy for many cancer patients with cancer, as well as patients with some other nonmalignant hematologic disorders and certain congenital immune deficiencies. Kidney complications after HSCT in a form of acute kidney injury is associated with significant morbidity and worse patient outcome. Read More

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Belatacept as a Treatment Option in Patients with Severe BK Polyomavirus Infection and High Immunological Risk-Walking a Tightrope between Viral Control and Prevention of Rejection.

Viruses 2022 05 9;14(5). Epub 2022 May 9.

Department of Medicine D, Division of General Internal Medicine, Nephrology and Rheumatology, University Hospital of Münster, 48149 Münster, Germany.

Balancing the immune system with immunosuppressive treatment is essential in kidney transplant recipients to avoid allograft rejection on the one hand and infectious complications on the other. BK polyomavirus nephropathy (BKPyVAN) is a viral complication that seriously threatens kidney allograft survival. Therefore, the main treatment strategy is to reduce immunosuppression, but this is associated with an increased rejection risk. Read More

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Robotic-assisted laparoscopy living donor nephrectomy: Technique and results of a monocentric retrospective series.

Prog Urol 2022 Jul 24;32(8-9):567-576. Epub 2022 May 24.

Service d'urologie, UPEC, hôpital Henri-Mondor, Créteil, France.

Introduction: Robot-assisted nephrectomy for living kidney donation (LKD) has been described in the literature as a safe and reproducible technique in high volume centers with extensive robotic surgery experience. Any surgical procedure in a healthy individual ought to be safe in regards to complications. The objective of this study was to evaluate the Robotic-assisted Living Donor Nephrectomy (RLDN) experience in a robotic surgery expert center. Read More

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The learning curve for open and minimally-invasive kidney transplantation: a systematic review by the European Association of Urology Young Academic Urologists kidney transplantation working group.

Minerva Urol Nephrol 2022 May 27. Epub 2022 May 27.

Department of Urology, Fundació Puigvert, Autonoma University of Barcelona, Barcelona, Spain.

Introduction: There is lack of evidence on the impact of surgeons' learning curve on postoperative outcomes after open (OKT) or minimally-invasive (robot-assisted) kidney transplantation (RAKT). The aim of the review was to assess the learning curve (LC) for OKT and RAKT, focusing on intra-, peri-operative and functional outcomes.

Evidence Acquisition: A systematic review of the English-language literature published between 01/01/2000 - 10/12/2021 was conducted using the MEDLINE (Via PubMed), Web of Science and the Cochrane Library databases according to the principles highlighted by the EAU Guidelines Office and the PRISMA statement recommendations. Read More

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Anti-T-Lymphocyte Immunoglobulin (Grafalon) as an Induction Agent for Renal Transplantation: A Real-World, Retrospective, Single-Center Experience.

Exp Clin Transplant 2022 05;20(5):480-486

From the Department of Nephrology, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, India.

Objectives: Polyclonal antithymocyte globulins are widely used in the induction regimens of solid-organ transplant recipients; however, their doses and outcomes remain to be standardized in Indian patients. We report our clinical experience from the real-world use of Grafalon (an anti-T-lymphocyte globulin; ATG-Fresenius) as an induction agentin renal transplant recipients from India.

Materials And Methods: In this retrospective, single- center, observational study, we analyzed the medical records of 177 consecutive, kidney-only transplant recipients who received induction therapy with Grafalon from September 2016 to March 2018 at our center. Read More

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Glomerular Diseases of the Kidney Allograft: Toward a Precision Medicine Approach.

Semin Nephrol 2022 01;42(1):29-43

Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY. Electronic address:

The continual development of potent immunosuppressive regimens has led to a decreased incidence of acute rejection and improvement of short-term kidney allograft survival. In contrast to acute rejection, glomerular diseases of the kidney allograft are being encountered more frequently and are emerging as leading causes of late kidney allograft failure. Although data on the pathogeneses of glomerular diseases in the kidney allograft are sparse, cumulative evidence suggests that post-transplant glomerular diseases may be the result of inherited predispositions and immunologic triggers. Read More

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January 2022