32,292 results match your criteria Kidney Transplantation Surgical Complications


Bariatric Surgery in Prior Solid Organ Transplantation Patients: Is Race a Predictor of Adverse Outcomes?

Obes Surg 2020 Jul 2. Epub 2020 Jul 2.

Department of Clinical Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, 19140, USA.

Purpose: Metabolic and bariatric surgery (MBS) is increasingly performed in patients with previous solid organ transplantation (PSOT). In addition, controversy remains about whether racial disparity in outcomes following MBS exists. Therefore, the aim of this analysis was to determine if race independently predicts outcomes in MBS patients with PSOT. Read More

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http://dx.doi.org/10.1007/s11695-020-04813-9DOI Listing

Pediatric Kidney Transplant Experience in Ontario: A Review of Division of the Surgical and Medical Management Across Local Tertiary Care Institutions.

Can J Kidney Health Dis 2020 8;7:2054358120925712. Epub 2020 Jun 8.

Division of Urology, The Hospital for Sick Children, Toronto, ON, Canada.

Background: Our institution is the largest pediatric kidney transplantation (KT) center in Canada and the referral center for pediatric KT in Ontario. Pediatric KT recipients are referred to our center for KT and transferred back to their local tertiary care institutions for post-transplant care. This investigation assesses whether the current system of transferring patients back to their local tertiary care institutions following KT allows decreased burden and distribution of resources from a single centralized surgical center. Read More

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http://dx.doi.org/10.1177/2054358120925712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285935PMC

The weekend effect and workforce in kidney transplantation.

Authors:
John D Scandling

Transpl Int 2020 Jun 19. Epub 2020 Jun 19.

Professor of Medicine, Stanford University - Medicine, 750 Welch Road, Palo Alto, California, 94304, United States.

The weekend effect, an association of increased mortality with admission to hospital on the weekend, appears to be true albeit contested. Its cause is unknown but may be weekend staffing. Studies of transplant registries in the U. Read More

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http://dx.doi.org/10.1111/tri.13676DOI Listing

The use of different dialysis membranes in therapy of patients with multiple myeloma.

Polim Med 2019 Jul-Dec;49(2):67-70

Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, Poland.

Free light chains accumulation is the reason of kidney injury in patients with multiple myeloma. The removal of free light chains can improve patients prognosis and survival, and in some cases allows for dialysotherapy discontinuation. Unfortunately, conventional dialysis is not effective enough in terms of free light chains removal. Read More

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http://dx.doi.org/10.17219/pim/122014DOI Listing

Minimally Invasive Surgery Is Feasible in Patients with Liver and Kidney Transplantation.

Ann Transplant 2020 Jun 16;25:e922602. Epub 2020 Jun 16.

Department of Surgery, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi, Taiwan.

BACKGROUND Minimally invasive surgery (MIS) has rapidly advanced, but its use in transplant patients has lagged. We share our experience of MIS for patients after kidney and liver transplantation and compare our results with similar studies in the literature. MATERIAL AND METHODS This study included 14 MIS (12 laparoscopic, 2 transvaginal) procedures for 13 transplant cases (6 liver and 7 kidney) done from May 2006 to May 2018. Read More

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http://dx.doi.org/10.12659/AOT.922602DOI Listing

[Post-transplantation diabetes in kidney transplant: from the diabetologist point of view].

Rev Med Suisse 2020 Jun;16(697):1200-1205

Service d'endocrinologie, diabétologie et métabolisme, CHUV, 1011 Lausanne.

Post-transplantation diabetes (PTDM) exposes to increased morbidity (cardiovascular or infectious complications, early graft dysfunction) and to a risk of premature death. Recognition of risk factors is essential for early and individualized care. The management of a PTDM requires the use of oral antidiabetic treatments (metformin or DPP4 inhibitors) or GLP1 receptor agonists for their favorable effects on weight and kidney that seem ideal in this context. Read More

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Double Single-Side Kidney Transplants With Bench Vascular Reconstruction: A Further Challenge Beyond the Marginality Without Future Preclusions.

Transplant Proc 2020 Jun 3;52(5):1544-1546. Epub 2020 Jun 3.

Department of Organ Insufficiencies and Transplantation, General Surgery and Transplantation, University Hospital of Bologna, Bologna, Italy.

Background: Double kidney transplantation allows the use of marginal kidneys with a significant improvement in the recovery of renal function expected after transplantation, although with a greater anesthesiologic and surgical risk. One-sided positioning, more cautious in the event of functional exhaustion, can be complex due to vascular anomalies.

Materials And Methods: We report the case of 2 double unilateral kidney transplants with vascular reconstructions. Read More

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http://dx.doi.org/10.1016/j.transproceed.2020.02.184DOI Listing

Effects of Obesity on Postoperative Complications and Graft Survival After Kidney Transplantation.

Transplant Proc 2020 Jun 1. Epub 2020 Jun 1.

Service d'Urologie, Andrologie et Transplantation Rénale, CHU Besançon, France; Université de Franche-Comté, Besançon, France.

Objective: The objective of this study was to analyze the effects of obesity on postoperative complications and patient and graft survival after kidney transplantation.

Methods: We retrospectively included 506 patients who received a kidney transplant in our center during eleven years. Obesity was defined by a body mass index ≥ 30 kg/m based on World Health Organization criteria. Read More

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http://dx.doi.org/10.1016/j.transproceed.2020.02.178DOI Listing

Successful Kidney Transplantation Alone With Severe Left Ventricular Systolic Dysfunction of Ejection Fraction 14%: A Case Report.

Transplant Proc 2020 May 29. Epub 2020 May 29.

Department of Urology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.

It is well known that correction of uremia by kidney transplantation alone (KTA) improves left ventricular systolic dysfunction (LVSD). However, for kidney transplant candidates with extremely severe LVSD, KTA is considered to be contraindicated because of the high risk of peri-operative management. We report a case of successful kidney transplantation with severe LVSD with an ejection fraction (EF) of 14% and low systolic blood pressure (SBP) of approximately 65 to 80 mm Hg. Read More

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http://dx.doi.org/10.1016/j.transproceed.2020.02.146DOI Listing

Retroperitoneoscopy in the horse: Anatomical study of the retroperitoneal perirenal space and description of a surgical approach.

Equine Vet J 2020 May 30. Epub 2020 May 30.

Department of Surgery, Equine Clinic, ONIRIS, National College of Veterinary Medicine, Food Science and Engineering, Nantes, France.

Background: Surgical approaches to the kidneys and perirenal structures are uncommonly performed in horses and several complications have been described with the current procedures.

Objective: To describe the anatomy of the retroperitoneal perirenal space and investigate a retroperitoneal minimally invasive approach to access the kidney and perirenal structures in horses.

Study Design: Descriptive, cadaveric study. Read More

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http://dx.doi.org/10.1111/evj.13293DOI Listing

Robot-Assisted versus Laparoscopic Donor Nephrectomy: A Comparison of 250 Cases.

J Clin Med 2020 May 26;9(6). Epub 2020 May 26.

Department of Urology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humbold-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117 Berlin, Germany.

Living kidney donation is the best treatment for end-stage renal disease, however, the best surgical approach for minimally-invasive donor nephrectomy (DN) is still a matter of debate. This bi-centric study aimed to retrospectively compare perioperative outcomes and postoperative kidney function after 257 transperitoneal DNs including 52 robot-assisted (RDN) and 205 laparoscopic DNs (LDN). As primary outcomes, the intraoperative (operating time, warm ischemia time (WIT), major complications) and postoperative (length of stay, complications) results were compared. Read More

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http://dx.doi.org/10.3390/jcm9061610DOI Listing

Acute-on-Chronic Liver Failure.

N Engl J Med 2020 May;382(22):2137-2145

From the European Foundation for the Study of Chronic Liver Failure (EF Clif) and the European Association for the Study of the Liver-Chronic Liver Failure (EASL-CLIF) Consortium - both in Barcelona (V.A., R.M., R.J.); INSERM, Université de Paris, Centre de Recherche sur l'Inflammation, and Service d'Hépatologie, Hôpital Beaujon, Assistance Publique-Hôpitaux de Paris, Clichy - both in France (R.M.); and the Liver Failure Group, Institute for Liver Disease Health, University College London, Royal Free Hospital, London (R.J.).

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http://dx.doi.org/10.1056/NEJMra1914900DOI Listing

Inflammaging and Complement System: A Link Between Acute Kidney Injury and Chronic Graft Damage.

Front Immunol 2020 7;11:734. Epub 2020 May 7.

Nephrology, Dialysis and Transplantation Unit, Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, Bari, Italy.

The aberrant activation of complement system in several kidney diseases suggests that this pillar of innate immunity has a critical role in the pathophysiology of renal damage of different etiologies. A growing body of experimental evidence indicates that complement activation contributes to the pathogenesis of acute kidney injury (AKI) such as delayed graft function (DGF) in transplant patients. AKI is characterized by the rapid loss of the kidney's excretory function and is a complex syndrome currently lacking a specific medical treatment to arrest or attenuate progression in chronic kidney disease (CKD). Read More

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http://dx.doi.org/10.3389/fimmu.2020.00734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221190PMC

Salvage after Retroperitoneal Kidney Allograft Torsion.

Case Rep Transplant 2020 14;2020:8024598. Epub 2020 Jan 14.

Division of Transplantation, Department of Surgery, Yale University School of Medicine, New Haven, CT, USA.

Torsion of a transplanted kidney into the retroperitoneal space is a rare occurrence, with only three other reported cases. Failure after kidney transplantation is caused by surgical, immunological, and infective complications. Torsion is a complication that poses a serious risk of ischemic graft failure, and, if suspected, sonographic evaluation helps ascertain the diagnosis. Read More

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http://dx.doi.org/10.1155/2020/8024598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201506PMC
January 2020

Minimally invasive open pyeloplasty in children: Long-term follow-up.

Turk J Urol 2020 May 21. Epub 2020 May 21.

Kidney Transplantation Research Center, Isfahan University of Medical Sciences (IUMS), Isfahan, Iran.

Objective: Our aim was to report the long-term follow-up for minimally invasive open pyeloplasty in children.

Material And Methods: A total of 213 children with a mean age 16.33 months underwent miniature open pyeloplasty for ureteropelvic junction obstruction between January 2010 and May 2016. Read More

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http://dx.doi.org/10.5152/tud.2020.20011DOI Listing

Risk of Graft Failure in Kidney Recipients with Cured Post-Transplant Cancer.

J Korean Med Sci 2020 May 25;35(20):e166. Epub 2020 May 25.

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.

Background: Post-transplant cancer (PTC) is a critical complication after kidney transplantation. However, whether successfully cured PTC affects the long-term graft outcome remains unclear.

Methods: We retrospectively reviewed 1,629 kidney transplant recipients from 1995 to 2017 after excluding patients with post-transplant hematologic or advanced non-curable cancers and who underwent allograft nephrectomy because of cancer. Read More

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http://dx.doi.org/10.3346/jkms.2020.35.e166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246187PMC

Intraoperative Dialysis During Liver Transplantation.

Transplant Proc 2020 May 21. Epub 2020 May 21.

Department of Nephrology, Dialysis, and Internal Diseases, Medical University of Warsaw, Warsaw, Poland.

Background: Orthotopic liver transplantation (LT) is a technically complex surgical procedure associated with a major risk of hemodynamic instability and metabolic derangement, especially in patients with coexisting renal dysfunction. Some centers have applied intraoperative renal replacement therapy (ioRRT) to support patients with preoperative renal failure and prevent critical complications. Although there is a strong theoretical rationale for this treatment, there remains a paucity of definite data demonstrating its benefits. Read More

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http://dx.doi.org/10.1016/j.transproceed.2020.01.129DOI Listing

Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials.

Lancet 2020 05;395(10237):1627-1639

Department of Surgery, University of Regensburg, University Hospital Regensburg, Regensburg, Germany; Division of Personalized Tumor Therapy, Fraunhofer Institute for Experimental Medicine and Toxicology, Regensburg, Germany; Regensburg Center for Interventional Immunology, University of Regensburg, Regensburg, Germany. Electronic address:

Background: Use of cell-based medicinal products (CBMPs) represents a state-of-the-art approach for reducing general immunosuppression in organ transplantation. We tested multiple regulatory CBMPs in kidney transplant trials to establish the safety of regulatory CBMPs when combined with reduced immunosuppressive treatment.

Methods: The ONE Study consisted of seven investigator-led, single-arm trials done internationally at eight hospitals in France, Germany, Italy, the UK, and the USA (60 week follow-up). Read More

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http://dx.doi.org/10.1016/S0140-6736(20)30167-7DOI Listing

The emerging spectrum of cardiopulmonary pathology of the coronavirus disease 2019 (COVID-19): Report of 3 autopsies from Houston, Texas, and review of autopsy findings from other United States cities.

Cardiovasc Pathol 2020 Sep - Oct;48:107233. Epub 2020 May 7.

Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth), Houston, Texas, USA; Center for Advanced Cardiopulmonary Therapies and Transplantation, McGovern Medical School and Memorial Hermann Hospital-Texas Medical Center, Houston, Texas, USA.

This paper collates the pathological findings from initial published autopsy reports on 23 patients with coronavirus disease 2019 (COVID-19) from 5 centers in the United States of America, including 3 cases from Houston, Texas. Findings confirm that COVID-19 is a systemic disease with major involvement of the lungs and heart. Acute COVID-19 pneumonia has features of a distinctive acute interstitial pneumonia with a diffuse alveolar damage component, coupled with microvascular involvement with intra- and extravascular fibrin deposition and intravascular trapping of neutrophils, and, frequently, with formation of microthombi in arterioles. Read More

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http://dx.doi.org/10.1016/j.carpath.2020.107233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204762PMC
July 2020
2.336 Impact Factor

The weekend effect in kidney transplantation outcomes: a French cohort-based study.

Transpl Int 2020 May 19. Epub 2020 May 19.

CRTI UMR 1064, Inserm, Université de Nantes, ITUN, RTRS Centaure, Nantes, France.

Background: Numerous studies have reported a weekend effect on outcomes for diseases treated at hospitals. No study has been conducted in France for kidney transplantation. We therefore performed a cohort-based study to evaluate whether outcomes of kidney transplant recipients display a weekend effect. Read More

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http://dx.doi.org/10.1111/tri.13653DOI Listing

Relationship between rabbit anti-thymocyte globulin and development of PTLD and its aggressive form in renal transplant population.

Ren Fail 2020 Nov;42(1):489-494

Institute of Medical Sciences, Faculty of Medicine, University of Liverpool, Liverpool, UK.

: The aim of our study is to explore the relationship of rabbit anti-thymocyte globulin (R-ATG) on development of post-transplant lymphoproliferative disease (PTLD) and its aggressive forms (monomorphic PTLD and Hodgkin lymphoma) in renal transplant recipients.: All patients diagnosed with PTLD post-renal transplant in the United States' Organ Procurement and Transplantation Network from 2003 till 2013 and followed up till 2017 were retrospectively reviewed. Multi-variable logistic regression analysis assessed association of R-ATG to development of PTLD and its aggressive form. Read More

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http://dx.doi.org/10.1080/0886022X.2020.1759636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301714PMC
November 2020
0.775 Impact Factor

Therapeutic efficacy of two surgical methods on the secondary hyperparathyroidism.

Gland Surg 2020 Apr;9(2):321-328

Department of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China.

Background: This study aimed to investigate the clinical efficacy of two surgical methods on hyperparathyroidism secondary to uremia and summarize the advantages and disadvantages of both methods.

Methods: Uremic patients who received parathyroidectomy (PTX) in the last 3 years were divided into two groups according to the surgical methods used [subtotal parathyroidectomy (SPTX) group and total parathyroidectomy + autologous implantation (TPTX + AT) group]. TPTX was performed if less than 4 glands were found during surgery. Read More

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http://dx.doi.org/10.21037/gs.2020.03.08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225472PMC

Is a Retroaortic Vein a Risk Factor in Laparoscopic Living Donor Nephrectomy?

Urol Int 2020 May 15:1-5. Epub 2020 May 15.

Department of Urology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany,

Introduction: In living donor transplantation choosing the right donor and donor side for laparoscopic donor nephrectomy is a challenging task in clinical practice. Knowledge about anomalies in renal blood supply are crucial to evaluate the feasibility of the operative procedure. Few data so far exist whether the existence of a retroaortic left renal vein has an impact on living kidney transplantation outcome for donor and recipient. Read More

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http://dx.doi.org/10.1159/000507642DOI Listing

A 14-Year Follow-Up of a Combined Liver-Pancreas-Kidney Transplantation: Case Report and Literature Review.

Front Med (Lausanne) 2020 28;7:148. Epub 2020 Apr 28.

Department of Urology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.

To investigate the long-term effect of triple organ transplantation (liver, kidney, and pancreas) in a patient with end-stage liver disease, post chronic hepatitis B, cirrhosis, chronic renal failure, and insulin-dependent diabetes mellitus caused by chronic pancreatitis and to explore the optimal surgical procedure. A 43-year-old man with progressive emaciation and hypourocrinia for 2 months. Results indicated exocrine pancreatic insufficiency and insulin-dependent diabetes related to chronic pancreatitis (CP) after developing end-stage hepatic and renal failure. Read More

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http://dx.doi.org/10.3389/fmed.2020.00148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198728PMC

Molecular Mechanisms of Premature Aging in Hemodialysis: The Complex Interplay Between Innate and Adaptive Immune Dysfunction.

Int J Mol Sci 2020 May 12;21(10). Epub 2020 May 12.

Nephrology, Dialysis and Transplantation Unit, Department of Medical and Surgical Sciences, University of Foggia, 71100 Foggia, Italy.

Hemodialysis (HD) patient are known to be susceptible to a wide range of early and long-term complication such as chronic inflammation, infections, malnutrition, and cardiovascular disease that significantly affect the incidence of mortality. A large gap between the number of people with end-stage kidney disease (ESKD) and patients who received kidney transplantation has been identified. Therefore, there is a huge need to explore the underlying pathophysiology of HD complications in order to provide treatment guidelines. Read More

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http://dx.doi.org/10.3390/ijms21103422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279398PMC

Stenting the ureteroneocystostomy reduces urological complications in kidney transplantation: a noninferiority randomized controlled trial, SPLINT trial.

Transpl Int 2020 May 13. Epub 2020 May 13.

Department of Surgery, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.

The role of ureteral stents in living-donor kidney transplantation remains uncertain. In this randomized controlled trial (SPLINT), we compared urological complications in living-donor kidney transplantations performed with or without stents. We included 200 consecutive patients that received living-donor kidney transplantations at the Erasmus MC, University Medical Center, Rotterdam. Read More

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http://dx.doi.org/10.1111/tri.13638DOI Listing

Influence of Parathyroidectomy on Kidney Graft Function in Secondary and Tertiary Hyperparathyroidism.

Transplant Proc 2020 May 10. Epub 2020 May 10.

Department of Surgery, Campus Charité Mitte, Campus Virchow-Klinikum, Charité - Universitätsmedizin Berlin, Berlin, Germany. Electronic address:

Background: Timing of parathyroidectomy (PTX) remains controversial in candidates for kidney transplant with concomitant renal hyperparathyroidism (HPT). The aim of this retrospective study was to identify the influence of early vs late posttransplant PTX compared to pretransplant PTX on renal graft function and morbidity.

Methods: This single-center cohort study includes 57 patients with renal HPT and kidney transplantation treated between 2007 and 2017. Read More

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http://dx.doi.org/10.1016/j.transproceed.2020.03.024DOI Listing

Third-party vessel allografts in kidney and pancreas transplantation: Utilization, de novo DSAs, and outcomes.

Am J Transplant 2020 May 13. Epub 2020 May 13.

Division of Nephrology, Department of Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, USA.

Third-party vascular allografts (VAs) are an invaluable resource in kidney and pancreas transplantation when vascular reconstruction is needed and additional vessels from the organ donor are not available. We report the largest single-center experience to date on VA use, at a high-volume U.S. Read More

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http://dx.doi.org/10.1111/ajt.16009DOI Listing

Continuous renal replacement therapy and its impact on hyperammonaemia in acute liver failure.

Crit Care Resusc 2020 Jun;22(2):158-165

Department of Intensive Care, Austin Health, Melbourne, VIC, Australia.

Objective: Hyperammonaemia contributes to complications in acute liver failure (ALF) and may be treated with continuous renal replacement therapy (CRRT), but current practice is poorly understood.

Design: We retrospectively analysed data for baseline characteristics, ammonia concentration, CRRT use, and outcomes in a cohort of Australian and New Zealand patients with ALF.

Setting: All liver transplant ICUs across Australia and New Zealand. Read More

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Timely surgical intervention for ureteric complications ensures adequate graft function in renal transplantation: a 10-year review.

ANZ J Surg 2020 May 8. Epub 2020 May 8.

Department of Vascular and Transplantation Surgery, Monash Medical Centre, Melbourne, Victoria, Australia.

Background: Ureteric complications can cause significant morbidity in renal and simultaneous pancreas-kidney (SPK) transplantation. This 10-year review identified transplant patients with ureteric complications necessitating surgical intervention in an Australian tertiary centre.

Methods: The hospital records were scrutinized in detail to identify all patients who underwent renal or SPK transplantation from 1 June 2009 to 31 May 2019 with subsequent surgical management of ureteric complications. Read More

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http://dx.doi.org/10.1111/ans.15914DOI Listing

ENDOCRINOLOGY IN THE TIME OF COVID-19: Management of diabetes insipidus and hyponatraemia.

Eur J Endocrinol 2020 Jul;183(1):G9-G15

Department of Endocrinology, Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, Oxford, UK.

COVID-19 has changed the nature of medical consultations, emphasizing virtual patient counseling, with relevance for patients with diabetes insipidus (DI) or hyponatraemia. The main complication of desmopressin treatment in DI is dilutional hyponatraemia. Since plasma sodium monitoring is not always possible in times of COVID-19, we recommend to delay the desmopressin dose once a week until aquaresis occurs allowing excess retained water to be excreted. Read More

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http://dx.doi.org/10.1530/EJE-20-0338DOI Listing

Kidney Cancer Following Heart Transplantation, a Common Presentation of an Uncommon Malignancy: A Unique Case Series.

Isr Med Assoc J 2020 May;22(5):285-288

Department of Urology, Sheba Medical Center, Tel Hashomer, Israel.

Background: Heart transplantation (HT) success rate is limited by a high incidence of cancer post-HT. Data on kidney cancer following solid organ transplantation, especially HT, are limited, and only a few cases have been reported.

Objectives: To report a unique case series of detected kidney cancer following HT. Read More

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Robotic assisted nephrectomy for living kidney donation (RANLD) with use of multiple locking clips or ligatures for renal vascular closure.

Ann Transl Med 2020 Mar;8(6):305

Department of Visceral, Transplant, Thoracic and Vascular Surgery, University Hospital of Leipzig, Leipzig, Germany.

Background: Robotic assisted nephrectomy for living donation (RANLD) is a rapid emerging surgical technique competing for supremacy with totally laparoscopic and laparoscopic hand assisted techniques. Opinions about the safety of specific techniques of vascular closure in minimally invasive living kidney donation are heterogeneous and may be different for laparoscopic and robotic assisted surgical techniques.

Methods: We retrospectively analyzed perioperative and short-term outcomes of our first (n=40) RANLD performed with the da Vinci Si surgical platform. Read More

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http://dx.doi.org/10.21037/atm.2020.02.97DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186662PMC

Kidney transplantation and donation in the transgender population: A single-institution case series.

Am J Transplant 2020 Apr 30. Epub 2020 Apr 30.

Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

The medical needs of the transgender population are increasingly recognized within the US health care system. Hormone therapy and gender-affirming surgery present distinct anatomic, hormonal, infectious, and psychosocial issues among transgender kidney transplant donors and recipients. We present the first reported experience with kidney transplantation and donation in transgender patients. Read More

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http://dx.doi.org/10.1111/ajt.15963DOI Listing

Physical activity in elderly kidney transplant patients with multiple renal arteries.

Minerva Med 2020 Apr 23. Epub 2020 Apr 23.

General Surgery and Transplant Unit, Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.

Introduction: Kidney transplantation (KT) is the gold standard for treatment of patients with end- stage-renal disease. To expand the donor reserve, it is necessary to use marginal/suboptimal kidneys.

Methods: We retrospectively evaluated the short/long-term outcome of 34 KT elderly patients who received allografts with vascular abnormalities (MRA group), in comparison with 34 KT patients who received a kidney with a single renal artery (SRA group) pair-matched by age, length of time on dialysis, comorbidity and donor age. Read More

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http://dx.doi.org/10.23736/S0026-4806.20.06573-8DOI Listing

Early Complications After Kidney Transplantation in Patients Aged 60 Years and Older: A Single-Center, Paired-Kidney Analysis.

Transplant Proc 2020 Apr 22. Epub 2020 Apr 22.

Department of General, Vascular and Transplant Surgery, Medical University of Silesia, Katowice, Poland.

Objectives: As the population ages, the number of people suffering from cardiovascular diseases (CVD) and diabetes mellitus (DM) increases. The coexistence of these diseases can affect the results of kidney transplantation (KT) in the elderly. The aim of this study was to analyze surgical and nonsurgical complications in the early period after KT and to identify the factors that influence their development in recipients aged ≥ 60 years compared to younger recipients < 60 years. Read More

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http://dx.doi.org/10.1016/j.transproceed.2020.01.093DOI Listing

Recent Advances and Clinical Outcomes of Kidney Transplantation.

J Clin Med 2020 Apr 22;9(4). Epub 2020 Apr 22.

Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA.

Recent advances in surgical, immunosuppressive and monitoring protocols have led to the significant improvement of overall one-year kidney allograft outcomes. Nonetheless, there has not been a significant change in long-term kidney allograft outcomes. In fact, chronic and acute antibody-mediated rejection (ABMR) and non-immunological complications following kidney transplantation, including multiple incidences of primary kidney disease, as well as complications such as cardiovascular diseases, infections, and malignancy are the major factors that have contributed to the failure of kidney allografts. Read More

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http://dx.doi.org/10.3390/jcm9041193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230851PMC

Case 13-2020: A 29-Year-Old Man with High Blood Pressure, Renal Insufficiency, and Hematuria.

N Engl J Med 2020 Apr;382(17):1639-1647

From the Departments of Medicine (A.L.L., S.K.), Radiology (A.M.), and Pathology (K.J.T.), Massachusetts General Hospital, and the Departments of Medicine (A.L.L., S.K.), Radiology (A.M.), and Pathology (K.J.T.), Harvard Medical School - both in Boston.

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http://dx.doi.org/10.1056/NEJMcpc1916254DOI Listing

Relation Between Wound Complication and Lymphocele After Kidney Transplantation: A Monocentric Study.

Transplant Proc 2020 Jun 14;52(5):1562-1565. Epub 2020 Apr 14.

Operative Unit of General Surgery and Kidney Transplantation - Advanced Biomedical Science Department - University Federico II of Naples, Naples, Italy.

Introduction: Wound complication frequently arises after kidney transplantation and its risk factors are well known. In a previous paper we analyzed these factors, and in this new retrospective study we evaluate the influence of lymphocele in the development of wound complications.

Patients And Methods: From January 2000 to December 2018, 731 consecutive kidney transplants have been performed in our center. Read More

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http://dx.doi.org/10.1016/j.transproceed.2020.02.053DOI Listing

Metabolic Disorders with Kidney Transplant.

Clin J Am Soc Nephrol 2020 May 13;15(5):732-742. Epub 2020 Apr 13.

Department of Surgery, Section of Transplant, Yale University, New Haven, Connecticut

Metabolic disorders are highly prevalent in kidney transplant candidates and recipients and can adversely affect post-transplant graft outcomes. Management of diabetes, hyperparathyroidism, and obesity presents distinct opportunities to optimize patients both before and after transplant as well as the ability to track objective data over time to assess a patient's ability to partner effectively with the health care team and adhere to complex treatment regimens. Optimization of these particular disorders can most dramatically decrease the risk of surgical and cardiovascular complications post-transplant. Read More

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http://dx.doi.org/10.2215/CJN.09310819DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269213PMC

Selective Trans-arterial Embolization of Iatrogenic Vascular Lesions Did Not Influence the Global Renal Function After Partial Nephrectomy.

Urology 2020 Jul 10;141:108-113. Epub 2020 Apr 10.

Aix-Marseille University, APHM, Nord Academic Hospital, Dept. of Urology, Marseille, France.

Objective: To evaluate the renal function outcomes after selective trans-arterial embolization (SAE) of iatrogenic vascular lesions (IVL), including pseudoaneurysm and arteriovenous fistula, following partial nephrectomy (PN).

Materials And Methods: A multi-institutional study was conducted including consecutive patients who underwent PN between January 2009 and March 2019. Two surgical approaches were used: open and robot-assisted PN. Read More

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http://dx.doi.org/10.1016/j.urology.2020.03.036DOI Listing
July 2020
2.188 Impact Factor

[Managing patients in dialysis and with kidney transplant infected with Covid-19].

G Ital Nefrol 2020 Apr 9;37(2). Epub 2020 Apr 9.

Università degli Studi di Brescia, Dipartimento di Specialità Medico-Chirurgiche, Scienze Radiologiche e Sanità Pubblica, Brescia, Italia; ASST Spedali Civili di Brescia, Unità Operativa di Nefrologia, Brescia, Italia.

We are in the midst of a health emergency that is totally new for us all and that requires a concerted effort, especially when it comes to safeguarding patients on hemodialysis, and kidney transplant recipients. Brescia is currently a very active cluster of infections (2918 cases on the 17/03/2020), second only to Bergamo. The way our structure is organised has allowed us to treat nephropathic patients directly within the Nephrology Unit, following of course a great deal of reshuffling; at the moment, we are treating 21 transplanted patients and 17 on hemodialysis. Read More

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Impact of obesity on dialysis and transplant and its management.

Semin Dial 2020 05 10;33(3):279-285. Epub 2020 Apr 10.

Division of Nephrology, Department of Medicine, University of Cincinnati, Cincinnati, OH, USA.

Obesity is increasing to unprecedented levels, including in the end-stage kidney disease population, where upwards of 60% of kidney transplant patients are overweight or obese. Obesity poses additional challenges to the care of the dialysis patient, including difficulties in creating vascular access and inserting Tenckhoff catheters, higher rates of catheter malfunction and peritonitis, the need for longer and/or more frequent dialysis (or peritoneal dialysis [PD] exchanges) to achieve adequate clearance, increased metabolic complications particularly with PD, and obesity is a barrier to kidney transplantation. In this article, we review special considerations in performing PD, hemodialysis and transplant in the obese patient, as well as the evidence behind medical and surgical management of obesity in dialysis patients. Read More

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http://dx.doi.org/10.1111/sdi.12876DOI Listing

First considerations on the SARS-CoV-2 epidemic in the Dialysis Units of Piedmont and Aosta Valley, Northern Italy.

J Nephrol 2020 06;33(3):393-395

CMID-Nephrology and Dialysis Unit (ERK-Net Member), ASL Città di Torino - Hub S. Giovanni Bosco Hospital, Turin, Italy.

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http://dx.doi.org/10.1007/s40620-020-00732-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146073PMC

When ESKD complicates cancer screening and cancer treatment.

Semin Dial 2020 05 9;33(3):236-244. Epub 2020 Apr 9.

The University of Illinois College of Medicine, Urbana-Champaign and Carle Illinois College of Medicine, Urbana, IL, USA.

End-stage kidney disease (ESKD) affects the recommended screening, incidence, treatment, and mortality of cancer. Cancer occurring in a patient with ESKD can influence candidacy for kidney transplantation as well as dialysis decision-making and cancer treatment. Certain cancers are more common among ESKD patients, notably, viral-mediated cancers that are associated with human papilloma or hepatitis viruses, and urothelial cancers associated with analgesic and Balkan nephropathies. Read More

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http://dx.doi.org/10.1111/sdi.12879DOI Listing

Five compelling UTI questions after kidney transplant.

World J Urol 2020 Apr 7. Epub 2020 Apr 7.

Department of Urology, Shahid Labbafinejad Medical Center, Tehran, Iran.

Purpose: Urinary tract infection (UTI) is the most common bacterial infection among infectious complications in kidney transplant recipients (KTR). After transplantation, infections can result from surgical complications, donor-derived infections, pre-existing recipient infections, and nosocomial infections. Post-transplant infection is still a major cause of morbidity, mortality, graft dysfunction and rejection. Read More

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http://dx.doi.org/10.1007/s00345-020-03173-4DOI Listing
April 2020
2.666 Impact Factor

Early Postoperative Complications and Outcomes of Kidney Transplantation in Moderately Obese Patients.

Transplant Proc 2020 Apr 3. Epub 2020 Apr 3.

Department of General and Transplantation Surgery, Medical University of Warsaw, Warsaw, Poland.

Background: Obese renal transplant recipients (body mass index [BMI] ≥30 kg/m) are at risk of delayed graft function and postoperative complications, such as infections or delayed wound healing. There is also a tendency to exclude extremely obese patients from transplantation (KTx). Nonetheless, no association between obesity and increased mortality has been reported. Read More

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http://dx.doi.org/10.1016/j.transproceed.2020.02.110DOI Listing

Perioperative risks of bariatric surgery among patients with and without history of solid organ transplant.

Am J Transplant 2020 Apr 3. Epub 2020 Apr 3.

Department of General Surgery, Michigan Medicine, Ann Arbor, Michigan, USA.

Bariatric surgery is effective among patients with previous transplant in limited case series. However, the perioperative safety of bariatric surgery in this patient population is poorly understood. Therefore, we assessed the safety of bariatric surgery among previous-transplant patients using a database that captures >92% of all US bariatric procedures. Read More

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http://dx.doi.org/10.1111/ajt.15883DOI Listing