33,561 results match your criteria Kidney Transplantation Surgical Complications


Emerging biomarkers of delayed graft function in kidney transplantation.

Transplant Rev (Orlando) 2021 May 26;35(4):100629. Epub 2021 May 26.

Nephrology, Dialysis and Transplantation Unit, Advanced Research Center on Kidney Aging (A.R.K.A.), Department of Medical and Surgical Sciences, University of Foggia, Italy. Electronic address:

Delayed Graft Function (DGF) is one of the most common early complications in kidney transplantation, associated with poor graft outcomes, prolonged post-operative hospitalization and higher rejection rates. Given the severe shortage of high-quality organs for transplantation, DGF incidence is expected to raise in the next years because of the use of nonstandard kidneys from Extended Criteria Donors (ECD) and from Donors after Circulatory Death (DCD). Alongside conventional methods for the evaluation of renal allograft [e. Read More

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Kidney transplantation from expanded criteria donors: an increased risk of urinary complications. The UNyCORT* study.

BJU Int 2021 Jun 11. Epub 2021 Jun 11.

Clinique urologique, Hôpital Hôtel Dieu, CHU de Nantes, Nantes, France.

Objectives: To assess the impact of ECD (expanded criteria donors) on urinary complications in kidney transplantation.

Materials And Methods: UNyCORT is a cohort study based on the French prospective DIVAT cohort (Données Informatisées et VAlidées en Transplantation /Computerized and VAlidated Data in Transplantation). Data were extracted between January 1, 2002 and January 1, 2018 with one-year minimum follow-up, in relation to 44 pre-and post-operative variables. Read More

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Egyptian clinical practice guideline for kidney transplantation.

Arab J Urol 2021 Jan 3;19(2):105-122. Epub 2021 Jan 3.

Nephrology Department, Kasr El-Einy Medical School, Cairo University, Cairo, Egypt.

: To present the first Egyptian clinical practice guideline for kidney transplantation (KT). : A panel of multidisciplinary subspecialties related to KT prepared this document. The sources of information included updates of six international guidelines, and review of several relevant international and Egyptian publications. Read More

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January 2021

Case report of transplant renal artery stenosis secondary to mechanical renal artery kinking: Balloon angioplasty as a supportive diagnostic tool?

Int J Surg Case Rep 2021 May 29;83:106052. Epub 2021 May 29.

Avera Mckennan Hospital, University Health Center Department of Interventional, Radiology, 1325 S. Cliff Avenue, Sioux Falls, SD 57105, United States of America. Electronic address:

Introduction And Importance: Renal vascular complications are a significant cause of morbidity in living donor renal transplantation. Among renal vascular complications, transplant renal artery stenosis (TRAS) secondary to mechanical kinking is a rare but important cause of early graft dysfunction. Identifying this phenomenon and correcting the underlying cause is critical to graft viability in the post-operative period. Read More

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COVID-19 in normal, diseased and transplanted liver.

World J Gastroenterol 2021 May;27(20):2576-2585

Hepatology Unit, Department of Medicine, University of Tor Vergata, Rome 00133, Italy.

Starting from December 2019 the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has extended in the entire world giving origin to a pandemic. Although the respiratory system is the main apparatus involved by the infection, several other organs may suffer coronavirus disease 2019 (COVID-19)-related injuries. The human tissues expressing angiotensin-converting enzyme 2 (ACE2) are all possible targets of viral damage. Read More

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Therapy-resistant hypertension in pregnancy after live donor kidney transplantation

Orv Hetil 2021 06 6;162(23):924-926. Epub 2021 Jun 6.

3 Szegedi Tudományegyetem, Általános Orvostudományi Kar, Szülészeti és Nőgyógyászati Klinika, Szeged.

Összefoglaló. A veseátültetés a legnagyobb reményt nyújtja a végstádiumú vesebetegségben szenvedő nők számára, akik teherbe kívánnak esni. A veseátültetett beteg terhessége továbbra is kihívást jelent az immunszuppresszív gyógyszerek mellékhatásai, az allograftfunkció romlásának kockázata, a praeeclampsia és a magas vérnyomás káros anyai szövődményeinek rizikója, valamint a koraszülés, az alacsony születési súly kockázata miatt. Read More

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Coronavirus Disease 2019 and Kidney Transplantation in Saudi Arabia: Outcomes and Future Opportunities.

Ann Transplant 2021 Jun 4;26:e931832. Epub 2021 Jun 4.

Multi-Organ Transplant Center, King Fahad Specialist Hospital, Eastern Health Cluster, Dammam, Saudi Arabia.

BACKGROUND Kidney transplant services all over the world were severely impacted by the coronavirus disease 2019 pandemic. The optimum management of kidney transplant recipients with coronavirus disease 2019 remains uncertain. MATERIAL AND METHODS We conducted a multicenter cohort study of kidney transplant recipients with coronavirus disease 2019 infection in Saudi Arabia. Read More

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Robot-assisted Kidney Transplantation Is a Safe Alternative Approach for Morbidly Obese Patients with End-stage Renal Disease.

Int J Med Robot 2021 Jun 2:e2293. Epub 2021 Jun 2.

Division of Transplant Surgery, Department of Surgery, University of Virginia, Charlottesville, Virginia.

Background: Many centers deny obese patients with a body mass index (BMI) >35 access to kidney transplantation due to increased intraoperative and postoperative complications.

Methods: From August 2017 to December 2019, 73 consecutive cases of kidney transplantation in morbidly obese patients were enrolled at a single university at the initiation of a robotic transplant surgery program. Outcomes of patients who underwent robotic assisted kidney transplant (RAKT) were compared to frequency-matched patients undergoing open kidney transplant (OKT). Read More

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Spontaneous nephrocutaneous fistula due to xanthogranulomatous pyelonephritis with secondary enterocutaneous fistula: a rare case report.

Am J Clin Exp Urol 2021 15;9(2):177-181. Epub 2021 Apr 15.

School of Medicine, Isfahan University of Medical Sciences Isfahan, Iran.

Chronic infection, especially in the setting of obstruction like calculous disease, may result in the fistula tract development of fistula tract from kidney to the other proximal organs. However, nephrocutaneous fistula is a rare complication, and the primary cause of its development is previous surgical intervention, trauma, or malignancy. Our case was a 26-year-old Afghan man with xanthogranulomatous pyelonephritis (XGP) resulted in spontaneous nephrocutaneous fistula. Read More

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Guidelines for the acute care of severe limb trauma patients.

Anaesth Crit Care Pain Med 2021 May 28:100862. Epub 2021 May 28.

Soins Intensifs, Hôpitaux Universitaires de Genève, Genève, Suisse.

Goal: To provide healthcare professionals with comprehensive multidisciplinary expert recommendations for the acute care of severe limb trauma patients, both during the prehospital phase and after admission to a Trauma Centre.

Design: A consensus committee of 21 experts was formed. A formal conflict-of-interest (COI) policy was developed at the onset of the process and enforced throughout. Read More

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Step-by-step Development of a Cold Ischemia Device for Open and Robotic-assisted Renal Transplantation.

Eur Urol 2021 May 28. Epub 2021 May 28.

Department of Urology, Fundació Puigvert, Autonoma University of Barcelona, Spain.

Background: Kidney transplantation (KT) is the best renal replacement treatment. The rewarming time is associated with ischemia/reperfusion damage. In both the open (open KT [OKT]) and the robotic (robotic-assisted KT [RAKT]) approaches, ice slush is used to maintain graft temperature (T°) below 20 °C. Read More

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The utility of native ureter in the management of ureteral complications in children after renal transplantation.

Pediatr Transplant 2021 May 30:e14051. Epub 2021 May 30.

University of Wisconsin, Madison, WI, USA.

Background: Ureteral complications after renal transplantation in children are a major source of morbidity. Management is complex and variable.

Methods: With IRB approval, health records were retrospectively reviewed of patients who: were <18 years, underwent kidney transplant between 1997 and 2017, had at least 2 years of follow-up, and underwent interventions due to post-transplant ureteral complications. Read More

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Endarterectomy for Iliac Occlusive Disease during Kidney Transplantation: A Multicenter Experience.

Int J Angiol 2021 Jun 30;30(2):91-97. Epub 2020 Aug 30.

Division of Vascular and Endovascular Surgery, Mayo Clinic, Jacksonville, Florida.

Little is known about the surgical challenges and outcomes of kidney transplantation (KT) in the face of severe iliac occlusive disease (IOD). We aim to examine our institution's experience and outcomes compared with all KT patients. Retrospective review of our multi-institutional transplant database identified patients with IOD requiring vascular surgery involvement for iliac artery endarterectomy at time of KT from 2000 to 2018. Read More

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Cytotoxic T Lymphocytes (CTLs) and Kidney Transplantation: An Overview.

Methods Mol Biol 2021 ;2325:203-213

Nephrology Unit, Department of Medical and Surgical Sciences, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome, Italy.

Involvement of T lymphocytes in kidney transplantation is a well-developed topic; however, most of the scientific interest focused on the different type of CD4+ lymphocyte subpopulations. Few authors, instead, investigated the role of CD8+ T cells in renal transplantation and how deleterious they can be to long-term allograft survival. Recently, there has been a renewed interest in the CD8+ T cells involvement in the transplantation field with the aim to investigate the immunological mechanisms underlying the infiltration of CD8+ T cells and their biological functions in human kidney allografts. Read More

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January 2021

Case Report: Successful Response to Intravenous Immunoglobulin and Steroid Pulses in a Renal Transplant Recipient With Severe Covid-19 Disease and Associated Acute Allograft Failure.

Front Immunol 2021;12:671013. Epub 2021 May 11.

Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, Cordoba, Spain.

The impact of Covid-19 pneumonia caused by SARS-CoV-2 on transplanted populations under chronic immunosuppression seems to be greater than in normal population. Clinical management of the disease, particularly in those patients worsening after a cytokine storm, with or without allograft impairment and using available therapeutic approaches in the absence of specific drugs to fight against the virus, involves a major challenge for physicians. We herein provide evidence of the usefulness of high-dose intravenous immunoglobulin (IVIG) combined with steroid pulses to successfully treat a case of Covid-19 pneumonia in a single-kidney transplanted patient with mechanical ventilation and hemodialysis requirements in the setting of a cytokine storm. Read More

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Simultaneous right-sided nephrectomy with orthotopic liver and kidney transplantation-An alternative method for patients with autosomal dominant polycystic liver and kidney disease.

Langenbecks Arch Surg 2021 May 26. Epub 2021 May 26.

Department of General, Visceral and Vascular Surgery, University Hospital Jena, Am Klinikum 1, 07747, Jena, Germany.

Purpose: In patients suffering from autosomal dominant polycystic liver and kidney disease (ADPLKD), combined organ transplantation often poses a technical challenge due to the large volume of both organs. To simplify the transplantation procedure by improving the exposure of anatomical structures, we introduce a novel surgical technique of orthotopic liver and kidney transplantation.

Methods: The modified simultaneous liver and kidney transplantation technique via a right-sided L-incision included three steps: (1) right-sided nephrectomy in the recipient followed by (2) orthotopic liver transplantation in cava replacement technique and (3) the orthotopic kidney transplantation with arterial reconstruction to the right common iliac artery. Read More

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Long-term immunosuppression and multiple transplants predispose systemic lupus erythematosus patients with cytopenias to hematologic malignancies.

Medicine (Baltimore) 2021 May;100(21):e25985

Department of Medicine, State University of New York, Downstate Health Sciences University, Brooklyn, NY.

Abstract: Cytopenias in systemic lupus erythematosus (SLE) require clinical and laboratory workup and bone marrow (BM) examination to determine the cause and for appropriate patient management. Common causes include an increase in SLE activity, immune-mediated hemolysis, iron deficiency, antiphospholipid antibody syndrome, infection, or the effect of medications. We retrospectively evaluated the clinical and laboratory findings of patients with SLE and cytopenias who had undergone BM studies to determine the indicators of malignancy. Read More

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Graft kidney hydronephrosis caused by transplant ureter inguinal hernia: A case report.

Medicine (Baltimore) 2021 May;100(21):e25965

Department of Radiology, China Medical University Hospital.

Rationale: Ureteral obstruction of the graft kidney is a common complication of kidney transplantation. However, ureteral obstruction caused by inguinal hernia has rarely been reported. We present a rare case of ureteral obstruction with allograft dysfunction caused by an inguinal hernia. Read More

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Minimizing Post-Infusion Portal Vein Bleeding during Intrahepatic Islet Transplantation in Mice.

J Vis Exp 2021 May 10(171). Epub 2021 May 10.

Department of Surgery, Medical University of South Carolina; Ralph H. Johnson Veterans Affairs Medical Center;

Although the liver is currently accepted as the primary transplantation site for human islets in clinical settings, islets are transplanted under the kidney capsule in most rodent preclinical islet transplantation studies. This model is commonly used because murine intrahepatic islet transplantation is technically challenging, and a high percentage of mice could die from surgical complications, especially bleeding from the injection site post-transplantation. In this study, two procedures that can minimize the incidence of post-infusion portal vein bleeding are demonstrated. Read More

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METHYLENE BLUE FOR TREATMENT OF HOSPITALIZED COVID-19 PATIENTS: A RANDOMIZED, CONTROLLED, OPEN-LABEL CLINICAL TRIAL, PHASE 2.

Rev Invest Clin 2021 ;73(3):190-198

Department of Biochemistry, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Background: There is no pharmacological intervention on the treatment of hypoxemia and respiratory distress in COVID-19 patients.

Objective: The objective of the study was to study the effect of the reduced form of methylene blue (MB) on the improvement of oxygen saturation (SpO) and respiratory rate (RR).

Methods: In an academic medical center, 80 hospitalized patients with severe COVID-19 were randomly assigned to receive either oral MB along with standard of care (SOC) (MB group, n = 40) or SOC only (SOC group, n=40). Read More

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Transplantation of 2-Month-Old En Bloc Pediatric Kidneys After a Complex Vascular Reconstruction - Traveling 2500 Miles to Get Transplanted: A Case Report.

Am J Case Rep 2021 May 21;22:e931124. Epub 2021 May 21.

Department of Surgery, Miami Transplant Institute, University of Miami Miller School of Medicine, Jackson Memorial Hospital, Miami, FL, USA.

BACKGROUND En bloc pediatric kidneys (EBPK) are one potential solution to increase the number of organs available in the donor community, thus promoting transplantation of these allografts into adult recipients. However, EBPK transplantation has been traditionally considered suboptimal due to concerns for perioperative complications, mainly vascular thrombosis. We report an en bloc kidney transplantation using vascular grafts from another deceased donor to extend the EBPK aorta and vena cava and create a tension-free anastomosis with recipient external iliac vessels. Read More

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Cardiovascular mortality in liver and kidney transplant recipients: A retrospective analysis from a single institution.

Medicine (Baltimore) 2021 May;100(20):e26019

Division of Cardiology, University Hospital Merkur.

Abstract: Previous studies have demonstrated cardiovascular causes to be among the leading causes of death after liver (LT) and kidney transplantation (KT). Although both recipient populations have unique pre-transplant cardiovascular burdens, they share similarities in post-transplant exposure to cardiovascular risk factors. The aim of this study was to compare cardiovascular mortality after LT and KT. Read More

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Long Term Outcomes and Complications of Reno-portal Anastomosis in Liver Transplantation: Results from a Propensity Score-Based Outcome Analysis.

Transpl Int 2021 May 18. Epub 2021 May 18.

Transplantation Center, Cleveland Clinic, Cleveland, OH, USA.

Introduction: Diffuse splanchnic vein thrombosis (DSVT) remains a serious challenge in liver transplantation (LT). Reno-portal anastomosis (RPA) has previously been reported as a valid option for management of patients with DSVT during LT. The aim of this study was to evaluate posttransplant renal function and surgical outcomes of patients with DSVT who underwent RPA during LT. Read More

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The hip replacement type choice: presentation of difficulty and responsibility about a case

Orv Hetil 2021 05 16;162(20):800-805. Epub 2021 May 16.

1 Service d'Orthopédie et Traumatologie Centre Hospitalier Universitaire - Brugmann, Université Libre de Bruxelles, 4, place Van Gehuchten, 1020 Bruxelles, Belgique.

Összefoglaló. A felszínpótló, fém a fémen csípőízületi protézisek reneszánszukat élték a 2000-es években. Elsősorban fiatal, aktív betegek esetében javasolták használni a remélt elméleti előnyök, mint a combfej csontállományának megőrzése, a csípőízület biomechanikájának fenntartása, a luxatio kockázatának csökkentése, a polietilén törmelékek és kopástermékek hiánya miatt. Read More

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Contrast-enhanced ultrasound of transplant organs - liver and kidney - in children.

Pediatr Radiol 2021 May 12. Epub 2021 May 12.

Department of Radiology and Medical Imaging, University of Virginia Children's Hospital, Charlottesville, VA, USA.

Ultrasound (US) is the first-line imaging tool for evaluating liver and kidney transplants during and after the surgical procedures. In most patients after organ transplantation, gray-scale US coupled with color/power and spectral Doppler techniques is used to evaluate the transplant organs, assess the patency of vascular structures, and identify potential complications. In technically difficult or inconclusive cases, however, contrast-enhanced ultrasound (CEUS) can provide prompt and accurate diagnostic information that is essential for management decisions. Read More

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Postoperative acute kidney injury in adult non-cardiac surgery: joint consensus report of the Acute Disease Quality Initiative and PeriOperative Quality Initiative.

Nat Rev Nephrol 2021 May 11. Epub 2021 May 11.

Center for Critical Care Nephrology, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA.

Postoperative acute kidney injury (PO-AKI) is a common complication of major surgery that is strongly associated with short-term surgical complications and long-term adverse outcomes, including increased risk of chronic kidney disease, cardiovascular events and death. Risk factors for PO-AKI include older age and comorbid diseases such as chronic kidney disease and diabetes mellitus. PO-AKI is best defined as AKI occurring within 7 days of an operative intervention using the Kidney Disease Improving Global Outcomes (KDIGO) definition of AKI; however, additional prognostic information may be gained from detailed clinical assessment and other diagnostic investigations in the form of a focused kidney health assessment (KHA). Read More

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Pediatric liver and kidney transplantation in the era of COVID-19: a follow-up study from a tertiary referral center in Iran.

BMC Surg 2021 May 11;21(1):240. Epub 2021 May 11.

Shiraz Transplant Center, Abu-Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: We aimed to evaluate the impact of COVID-19 pandemic on pediatric transplant outcomes and determine whether to continue pediatric transplant activity or not, and how policies intended our center has been effective in preventing COVID-19 among organ transplant recipients.

Methods: We conducted a single-center, retrospective, cohort study of hospitalized pediatrics after organ transplantation at Shiraz transplant center since March to August 2020. All liver and kidney transplanted children were included the study and their laboratory and clinical related COVID-19 characteristics were followed up till 3 months after transplantation during hospitalization period and then weekly by the transplant committee. Read More

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Posterior cranial vault distraction osteogenesis in the immunocompromised patient.

Childs Nerv Syst 2021 May 10. Epub 2021 May 10.

Division of Plastic Surgery, Department of Surgery, Children's of Mississippi, University of Mississippi Medical Center, 2500 State Street, Jackson, MS, 39216, USA.

Purpose: The treatment of patients with multisuture craniosynostosis is complex and patient-dependent. Cranial distraction osteogenesis is a relatively new procedure for treatment of these patients, with its use increasing in many centers. With this increased use comes an expanding range of indications. Read More

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Clinical features of multidrug-resistant organism infections in early postoperative solid organ transplantation in a single center.

Ann Palliat Med 2021 Apr;10(4):4555-4562

Organ Transplantation Center, Panyu Campus, the Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

Background: The increasing occurrence of multidrug-resistant organisms (MDROs) infections has posed major challenge to solid organ transplantation (SOT). For SOT recipients, high-dose immunosuppressants and broad-spectrum antibiotics can markedly increase the risk of early postoperative MDRO infections and thus have adverse effects on the outcomes of SOT. Here, we analyzed the incidence and clinical features of early MDRO infections after SOT, in an attempt to provide new evidence for the control and treatment of early MDROs. Read More

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Tertiary hyperparathyroidism: a review.

Clin Ter 2021 May;172(3):241-246

Department of Surgical, Oncological and Oral Sciences, University of Palermo, Palermo, Italy.

Abstract: Tertiary hyperparathyroidism (HPT III) occurs when an excess of parathyroid hormone (PTH) is secreted by parathyroid glands, usually after longstanding secondary hyperparathyroidism. Some authorities reserve the term for secondary hyperparathyroidism that persists after successful renal transplantation. Long-standing chronic kidney disease (CKD) is associated with several metabolic disturbances that lead to increased secretion of PTH, including hyperphosphatemia, calcit-riol deficiency, and hypocalcaemia. Read More

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