352 results match your criteria Keratosis Pilaris


Seasonal Variability in Public Searches of Keratosis Pilaris: How the Internet can Illuminate a Pattern in Public Interest.

Dermatol Ther 2020 Jul 4:e13957. Epub 2020 Jul 4.

School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.

In this study, we examine keratosis pilaris search patterns using Google Trends to determine any seasonality. Monthly searches were collected from January 2004 to January 2020 using "keratosis pilaris" as the search term in the Google Trends database. United States search data was compared to monthly temperatures and tested for correlation. Read More

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http://dx.doi.org/10.1111/dth.13957DOI Listing

Keratosis pilaris-like eruption secondary to nilotinib in a child.

Pediatr Dermatol 2020 Jun 29. Epub 2020 Jun 29.

Department of Dermatology, University Hospital La Paz, Madrid, Spain.

Nilotinib is a new multitargeted tyrosine kinase inhibitor, which is used to treat chronic myelogenous leukemia when intolerance or recurrence to imatinib occurs. We report the case of a 14-year-old patient being treated with nilotinib who developed a keratosis pilaris-like eruption. This cutaneous adverse effect is a rare but increasingly reported side effect of this therapy. Read More

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http://dx.doi.org/10.1111/pde.14267DOI Listing

Assessment of 5-Aminolaevulinic Acid Photodynamic Therapy (ALA-PDT) in Chinese patients with actinic keratosis: Correlation of dermoscopic features with histopathology.

Australas J Dermatol 2020 May 18. Epub 2020 May 18.

Department of Dermatology, Peking University Third Hospital, Beijing, China.

Objectives: The study examines the changes in dermoscopic features of actinic keratosis (AK) after photodynamic therapy, and delineates the association between AK dermoscopic and histopathological findings.

Methods: A total of 21 patients (23 lesions) with pathologically confirmed actinic keratosis who received 5-aminolaevulinic acid (ALA) photodynamic therapy (ALA-PDT) were enrolled. The numbers of PDT treatments were: 1, n = 1; 2, n = 2; 3, n = 10; 4, n = 6; 5, n = 2; 6, n = 2). Read More

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http://dx.doi.org/10.1111/ajd.13289DOI Listing

Two is better than one: The combined effects of glycolic acid and salicylic acid on acne-related disorders.

J Cosmet Dermatol 2020 Apr 6. Epub 2020 Apr 6.

William Beaumont Hospital-Royal Oak, Royal Oak, MI.

Background: Many companies capitalized on treatable skin conditions by providing expensive prescription medications or high-end over-the-counter cosmetics. However, patients have become more apprehensive toward these medications in lieu of their often-detrimental side effect profile and reactivity with sensitive skin.

Aims: We developed a serum was created to counteract this budding problem. Read More

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http://dx.doi.org/10.1111/jocd.13387DOI Listing

Skin and nails abnormalities in a patient with ZTTK syndrome and a de novo mutation in SON.

Pediatr Dermatol 2020 May 11;37(3):517-519. Epub 2020 Feb 11.

Department of Dermatology, Hospital Universitario La Paz, Madrid, Spain.

Zhu-Tokita-Takenouchi-Kim (ZTTK) syndrome is a rare, severe, and recently described multisystem developmental disorder characterized by delayed psychomotor development and intellectual disability, characteristic facial features, hypotonia, poor overall growth, and visual abnormalities. Mucocutaneous manifestations have not been reported so far among individuals with ZTTK syndrome. Herein, we present a patient with ZTTK syndrome due to a de novo mutation in SON gene, who has dental abnormalities and retronychia of the toenails. Read More

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http://dx.doi.org/10.1111/pde.14113DOI Listing

Intense Pulsed-light Therapy Significantly Improves Keratosis Pilaris: A Randomized, Double-blind, Sham Irradiation-controlled Trial.

J Clin Aesthet Dermatol 2019 Oct 1;12(10):E53-E57. Epub 2019 Oct 1.

Drs. Maitriwong, Tangkijngamvong, and Asawanonda are with Division of Dermatology in the Department of Medicine, Faculty of Medicine at the Chulalongkorn University in Bangkok, Thailand.

Keratosis pilaris (KP) is a common benign follicular disorder for which various topical and laser treatments have been used, with limited efficacy. We evaluated the efficacy of intense pulsed light (IPL) therapy for the reduction of skin roughness, erythema, and hyperpigmentation in Thai subjects with KP. Twenty-four Thai patients with untreated KP on the upper outer arms were enrolled in a randomized, double-blind study. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937144PMC
October 2019

Hyperkeratotic Skin Adverse Events Induced by Anticancer Treatments: A Comprehensive Review.

Drug Saf 2020 May;43(5):395-408

Oncodermatology, Institut Claudius REGAUD and Institut Universitaire du Cancer Toulouse Oncopole, 1 avenue Irène Joliot-Curie 31059, Toulouse Cedex 9, France.

Hyperkeratotic skin adverse events are a group of toxic effects, characterized by the disruption of epidermal homeostasis and interaction with keratinocyte proliferation/differentiation or keratinocyte survival, and frequently reported with systemic anticancer treatments. These types of reactions include hand-foot skin reaction or palmoplantar keratoderma, induced psoriasis, keratosis pilaris-like or pityriasis rubra pilaris-like rashes, Grover's disease, and contact hyperkeratosis. Cutaneous squamoproliferative lesions are also described because of the presence of abnormal keratinocyte proliferation. Read More

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http://dx.doi.org/10.1007/s40264-020-00907-6DOI Listing

"Comparative study between the efficacy of fractional CO2 laser, Q-switched Nd:YAG laser (1064 nm), and both types in treatment of keratosis pilaris".

Lasers Med Sci 2020 Jan 11. Epub 2020 Jan 11.

Kasr El Aini Cairo University Hospital, Cairo, Egypt.

The aim of this study was to assess and compare the efficacy of fractional CO2 laser, Q-switched Nd:YAG laser (1064 nm), and their combined use in treatment of keratosis pilaris. The study included twenty female patients. For each patient, three areas were randomly assigned to treatment by either fractional CO2 laser (area A) or Q-switched laser (1064 nm) (area C), or both types of laser (area B). Read More

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http://dx.doi.org/10.1007/s10103-020-02956-wDOI Listing
January 2020

Diabetic Skin Changes Can Benefit from Moisturizer and Cleanser Use: A Review

J Drugs Dermatol 2019 Dec;18(12):1211-1217

INTRODUCTION: Diabetes mellitus (DM) associated skin changes, which may be the first sign of DM in undiagnosed patients. Frequently these patients present with dry skin, which may benefit from the use of gentle cleansers and moisturizers. A review paper was developed to explore DM-associated skin changes and possible benefits of cleanser and moisturizer use. Read More

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December 2019

The different faces of mycosis fungoides: results of a single-center study.

Int J Dermatol 2020 Mar 29;59(3):314-320. Epub 2019 Nov 29.

1st Department of Dermatology-Venereology, Faculty of Medicine, National and Kapodistrian University of Athens, Cutaneous Lymphoma Clinic, "A. Sygros" Hospital for Skin & Venereal Diseases, Athens, Greece.

Background: Mycosis fungoides (MF) accounts for the majority of cutaneous lymphomas. Apart from the predominant Alibert-Bazin type, several clinicopathological variants of diverse prevalence and biological behavior have been described. Data on clinical and epidemiological aspects of MF clinical subtypes are still weak. Read More

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http://dx.doi.org/10.1111/ijd.14735DOI Listing

Keratosis Pilaris.

Authors:

Pediatr Dermatol 2019 Nov;36(6):937-938

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http://dx.doi.org/10.1111/pde.14062DOI Listing
November 2019

Innovative 1064-nm Nd:YAG Laser Significantly Improves Keratosis Pilaris, A Randomized, Double-Blind, Sham-Irradiation-Controlled Trial.

Lasers Surg Med 2020 Jul 11;52(6):509-514. Epub 2019 Nov 11.

Department of Medicine, Division of Dermatology, Faculty of Medicine, Chulalongkorn University, 1873 Rama 4 Road, Bangkok, 10330, Thailand.

Background And Objective: Keratosis pilaris (KP) is a common follicular disorder for which various topical agents and energy-based devices have been used with some efficacy. To evaluate the efficacy of a novel 1064-nm Nd:YAG laser for the reduction of skin roughness, erythema, and hyperpigmentation in KP subjects.

Study Design/materials And Methods: Twenty-three subjects with untreated KP on the upper outer arms participated in a randomized, single-blind fashion. Read More

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http://dx.doi.org/10.1002/lsm.23184DOI Listing

[Keratosis pilaris].

Pan Afr Med J 2019 30;33:274. Epub 2019 Jul 30.

Hôpital Civil Tétouan, Tétouan, Maroc.

Keratosis pilaris is characterized by small bumps around hair follicles. Keratosis pilaris simplex results in gray and keratotic papules mainly on the arms, thighs and buttocks. It mainly affects women. Read More

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http://dx.doi.org/10.11604/pamj.2019.33.274.16158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814928PMC
November 2019
1 Read

Pediatric case of Graham Little Piccardi Lassueur syndrome - A rare entity.

Drug Discov Ther 2019 Nov 27;13(5):294-296. Epub 2019 Oct 27.

Department of Tropical Medicine, School of Tropical Medicine, Kolkata, West Bengal, India.

Graham Little Piccardi Lassueur syndrome (GLPLS) is a rare dermatosis characterized by patchy cicatricial alopecia of scalp, rapidly developing keratosis pilaris like follicular papules over trunk and extremities, and noncicatricial loss of axillary and pubic hair. This syndrome which is mostly seen in middle aged post-menopausal females (between ages 30-70)has rarely ever been described in the pediatric age group. We report a case of a 15 year old girl presenting to us with this rare syndrome. Read More

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http://dx.doi.org/10.5582/ddt.2019.01055DOI Listing
November 2019
1 Read

Follicular occlusion disorders in Down syndrome patients.

Pediatr Dermatol 2020 Jan 18;37(1):219-221. Epub 2019 Oct 18.

Department of Dermatology, Baylor College of Medicine, Houston, TX, USA.

Disorders involving follicular occlusion, such as hidradenitis suppurativa, folliculitis, acneiform eruptions, and pilonidal cysts, have shown an increased prevalence in the Down syndrome (DS) population, but there are limited published data examining this association. We conducted a retrospective chart review of 243 DS patients presenting to a pediatric dermatology clinic to further examine the prevalence of disorders of follicular occlusion in DS patients. Our study showed high rates of disorders of follicular occlusion in DS patients, with prevalent disorders including folliculitis (21. Read More

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http://dx.doi.org/10.1111/pde.14012DOI Listing
January 2020
2 Reads

Skin changes in the obese patient.

J Am Acad Dermatol 2019 Nov;81(5):1037-1057

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida; Veterans Affairs Miami Health Care System, Miami, Florida. Electronic address:

Obesity is a worldwide major public health problem with an alarmingly increasing prevalence over the past 2 decades. The consequences of obesity in the skin are underestimated. In this paper, we review the effect of obesity on the skin, including how increased body mass index affects skin physiology, skin barrier, collagen structure, and wound healing. Read More

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http://dx.doi.org/10.1016/j.jaad.2018.12.070DOI Listing
November 2019
1 Read

Dermoscopy of Keratosis Pilaris.

Indian Dermatol Online J 2019 Sep-Oct;10(5):613-614. Epub 2019 Aug 28.

Department of Dermatology, Poornima Hospital, HMT Layout, RT Nagar, Bengaluru, Karnataka, India.

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http://dx.doi.org/10.4103/idoj.IDOJ_279_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743401PMC
August 2019
3 Reads

Clinical and dermoscopic evaluation of fractional carbon dioxide laser in management of keratosis pilaris in Egyptian type skin.

J Cosmet Dermatol 2020 May 16;19(5):1110-1120. Epub 2019 Sep 16.

Department of Dermatology, Venereology & Andrology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.

Background: Numerous treatment modalities for keratosis pilaris have been tried with limited success.

Aim: To determine the efficacy, safety, and tolerability of fractional CO2 laser in the treatment of KP.

Patients And Methods: This prospective, single-blinded split-body placebo-controlled comparative study was conducted on 60 patients with bilateral KP of arms (group A) and thighs (group B). Read More

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http://dx.doi.org/10.1111/jocd.13140DOI Listing
May 2020
1 Read

Hidradenitis Suppurativa in a Patient with Smith-Magenis Syndrome: A Case Report.

Cureus 2019 Jun 22;11(6):e4970. Epub 2019 Jun 22.

Dermatology, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, USA.

Hidradenitis suppurativa (HS) is an inflammatory disorder characterized by recurrent painful nodules and draining sinus tracts with subsequent scarring. HS has been associated with several dermatologic syndromes including the follicular occlusion tetrad, PASH (pyoderma gangrenosum, acne, and suppurativa hidradenitis), PAPASH (pyogenic arthritis, pyoderma gangrenosum, acne, and suppurativa hidradenitis), and SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndromes. However, aside from the well-established association between HS and Down Syndrome, it has rarely been reported in association with other multisystem genetic diseases. Read More

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http://dx.doi.org/10.7759/cureus.4970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701913PMC
June 2019
3 Reads

Skin abnormalities in the Finnish National Gallery.

Authors:
Nicolas Kluger

J Cosmet Dermatol 2020 Apr 24;19(4):960-963. Epub 2019 Aug 24.

Department of Dermatology, Allergology and Venereology, Helsinki University Central Hospital, Helsinki, Finland.

The search for clinical signs suggestive of diseases and medical analysis in works of art and portraits is also known as iconodiagnosis. It raises discussions about underlying diseases and about whether the artist intended to represent them. We assessed the frequency of cutaneous signs in paintings on display in the permanent collections of the Ateneum and Sinebrychoff Art Museums, Finnish National Gallery in Helsinki. Read More

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http://dx.doi.org/10.1111/jocd.13095DOI Listing
April 2020
2 Reads

Noonan-Syndrom mit multiplen Lentigines und ausgeprägter Keratosis pilaris.

J Dtsch Dermatol Ges 2019 Jul;17(7):748-751

Department of Dermatology, Hospital Universitario de Cabueñes, Gijón, Spain.

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http://dx.doi.org/10.1111/ddg.13880_gDOI Listing
July 2019
3 Reads

Dermatologic Problems Commonly Seen by the Allergist/Immunologist.

J Allergy Clin Immunol Pract 2020 Jan 25;8(1):102-112. Epub 2019 Jul 25.

Division of Allergy and Immunology, Department of Internal Medicine, University of South Florida Morsani College of Medicine, Tampa, Fla.

Allergists/immunologists see a variety of skin disorders, some of which have a known immunologic basis whereas others do not. We review the prevalence, etiology, clinical presentation, and effective and low-cost care of common dermatologic conditions seen in outpatient practices. Conditions discussed include pityriasis alba, seborrheic dermatitis, rosacea, acne, tinea infections, intertrigo, lichen planus, tinea versicolor, lichen simplex chronicus, scabies, pityriasis rosea, keratosis pilaris, and seborrheic keratosis. Read More

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http://dx.doi.org/10.1016/j.jaip.2019.07.019DOI Listing
January 2020
5 Reads

Keratosis pilaris-like eruption induced by nilotinib.

G Ital Dermatol Venereol 2019 Jul 12. Epub 2019 Jul 12.

Dermatology Department, Ramon y Cajal University Hospital, Madrid, Spain.

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http://dx.doi.org/10.23736/S0392-0488.19.06333-8DOI Listing
July 2019
3 Reads

Noonan syndrome with multiple lentigines and prominent keratosis pilaris.

J Dtsch Dermatol Ges 2019 Jul 18;17(7):749-751. Epub 2019 Jun 18.

Department of Dermatology, Hospital Universitario de Cabueñes, Gijón, Spain.

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http://dx.doi.org/10.1111/ddg.13880DOI Listing
July 2019
6 Reads

Widespread keratosis pilaris-like eruption in an immunocompromised child.

JAAD Case Rep 2019 Apr 5;5(4):352-354. Epub 2019 Apr 5.

Department of Dermatology, University of Utah School of Medicine, Salt Lake City, Utah.

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http://dx.doi.org/10.1016/j.jdcr.2019.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453831PMC
April 2019
18 Reads

Follicular psoriasis induced by pembrolizumab in a patient with advanced non-small-cell lung cancer.

Int J Dermatol 2019 Aug 9;58(8):e151-e152. Epub 2019 Apr 9.

Dermatology, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy.

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http://dx.doi.org/10.1111/ijd.14457DOI Listing
August 2019
1 Read

A case of keratosis pilaris rubra in a 17th century portrait?

Authors:
N Kluger

J Eur Acad Dermatol Venereol 2019 08 3;33(8):1450-1451. Epub 2019 Apr 3.

Department of Dermatology, Allergology and Venereology, Helsinki University Central Hospital, Meilahdentie 2, PO Box 160, 00029 HUS, Helsinki, Finland.

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http://doi.wiley.com/10.1111/jdv.15561
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http://dx.doi.org/10.1111/jdv.15561DOI Listing
August 2019
10 Reads

Cutaneous findings in Bardet-Biedl syndrome.

Int J Dermatol 2019 Oct 20;58(10):1160-1164. Epub 2019 Feb 20.

Marshfield Medical Center, Marshfield, WI, USA.

Background: Bardet-Biedl syndrome (BBS) is a rare, pleiotropic syndrome and member of a diverse group of disorders known as ciliopathies. Improved understanding of dermatoses in BBS will further understanding of the syndrome and will help define the role of dermatologists in providing care for patients with BBS. The purpose of this study was to describe the cutaneous phenotype of BBS in patients attending a large, multispecialty BBS clinic. Read More

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http://dx.doi.org/10.1111/ijd.14412DOI Listing
October 2019
10 Reads

Reaccion acneiforme noduloquistica secundaria a vemurafenib con buena respuesta a isotretinoina oralSevere acneiform eruption associated with vemurafenib with response to isotretinoin.

Dermatol Online J 2018 Aug 15;24(8). Epub 2018 Aug 15.

Department of Dermatology, Hospital Universitario Fundacion Alcorcon, Madrid.

Vemurafenib, a kinase inhibitor that targets tumors with the BRAF V600E mutation, is a promising option for unresectable or metastatic melanoma. Cutaneous side-effects have been reported including alopecia, photosensitivity, squamous cell carcinoma, keratoacanthomas, keratosis pilaris-like eruption, and palmoplantar hyperkeratosis. Acneiform eruptions have been reported in 3%-6% of the patients treated with BRAF inhibitors,and 5 cases are described in the literature. Read More

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August 2018
9 Reads

Atrophoderma Vermiculatum in a 12-Year-Old Girl.

Skinmed 2018;16(6):421-422. Epub 2018 Dec 21.

Department of Dermatology and Allergy Centre, Odense University Hospital, Odense, Denmark.

A 12-year-old girl was referred to the University Hospital of Southern Denmark with multiple small, punched-out scars on both cheeks, proximal and lateral on the nose, and in the auricular conchae. According to the history, the skin lesions had been progressing since the age of 3 years. The family had consulted several dermatologists and one plastic surgeon without any specific diagnosis or therapeutic solution. Read More

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October 2019
1 Read

Severe vemurafenib-induced photosensitivity in a 6-year-old boy.

Pediatr Dermatol 2019 Jan 26;36(1):e62-e63. Epub 2018 Nov 26.

Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

Vemurafenib, a selective BRAF kinase inhibitor, has been found to induce several cutaneous adverse effects, ranging from a keratosis pilaris-like reaction to squamous cell carcinoma. While photosensitivity has been well described as one of these manifestations, we report a case of a 6-year-old boy on vemurafenib who developed a severe blistering sunburn after only two 30-minute episodes of sun exposure. A brief review of other common cutaneous adverse effects of vemurafenib is also provided. Read More

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http://dx.doi.org/10.1111/pde.13720DOI Listing
January 2019
9 Reads

Dermatological manifestations in Noonan syndrome: a prospective multicentric study of 129 patients positive for mutation.

Br J Dermatol 2019 06 18;180(6):1438-1448. Epub 2019 Jan 18.

University of Paris-Diderot, Paris, France.

Background: Data on dermatological manifestations of Noonan syndrome (NS) remain heterogeneous and are based on limited dermatological expertise.

Objectives: To describe the dermatological manifestations of NS, compare them with the literature findings, and test for dermatological phenotype-genotype correlations with or without the presence of PTPN11 mutations.

Methods: We performed a large 4-year, prospective, multicentric, collaborative dermatological and genetic study. Read More

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http://doi.wiley.com/10.1111/bjd.17404
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http://dx.doi.org/10.1111/bjd.17404DOI Listing
June 2019
24 Reads

And next… Adnexa: Ulerythema ophryogenes and keratosis pilaris.

Eur J Dermatol 2018 Aug;28(4):566-567

Department of Dermatology and Venereology, Hospital de Santo António dos Capuchos - Centro Hospitalar de Lisboa Central, Alameda de Santo António dos Capuchos, 1169-050 Lisbon, Portugal.

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http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/ej
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http://dx.doi.org/10.1684/ejd.2018.3385DOI Listing
August 2018
16 Reads

Dermatological aspects of the S2k guidelines on Down syndrome in childhood and adolescence.

J Dtsch Dermatol Ges 2018 Oct;16(10):1289-1295

Department of Pediatrics and Adolescent Medicine, Division of Pediatric Endocrinology and Diabetology, Saarland University Medical Center, Homburg, Germany.

With an incidence of 1 in 700 births, Down syndrome (DS) is not an uncommon condition. It is associated with various disorders of different organ systems. Serious disorders include cardiac defects and leukemia. Read More

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http://doi.wiley.com/10.1111/ddg.13665
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http://dx.doi.org/10.1111/ddg.13665DOI Listing
October 2018
15 Reads

Dermatologische Aspekte aus der S2k-Leitlinie zum Down-Syndrom im Kindes- und Jugendalter.

J Dtsch Dermatol Ges 2018 Oct;16(10):1289-1296

Universität des Saarlandes, Kliniken für Kinder- und Jugendmedizin, Sektion Pädiatrische Endokrinologie und Diabetologie, Homburg.

Das Down-Syndrom (DS) ist mit einer Inzidenz von 1 : 700 aller Geburten nicht selten und mit diversen Erkrankungen unterschiedlicher Organsysteme assoziiert. Zu den schwerwiegenden Erkrankungen zählen Herzfehler und Leukämie. Letztere zeigt sich im Neugeborenenalter und geht nicht immer in eine klassische myeloische Leukämie über (transiente myeloproliferative Erkrankung). Read More

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http://doi.wiley.com/10.1111/ddg.13665_g
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http://dx.doi.org/10.1111/ddg.13665_gDOI Listing
October 2018
21 Reads

Keratosis pilaris rubra with mucin deposition.

J Cutan Pathol 2018 Dec 21;45(12):958-961. Epub 2018 Oct 21.

Department of Dermatology, University of California Irvine, Irvine, California.

Keratosis pilaris (KP) is a benign cutaneous disorder characterized by folliculocentric hyperkeratotic papules most often occurring on the proximal extremities. Erythema is usually limited to perifollicular skin, but when keratosis pilaris presents on a background of confluent erythema, the term keratosis pilaris rubra (KPR) is used. The histological findings associated with KP have not been well described in the literature. Read More

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http://doi.wiley.com/10.1111/cup.13365
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http://dx.doi.org/10.1111/cup.13365DOI Listing
December 2018
25 Reads

A mosaic intragenic microduplication of LAMA1 and a constitutional 18p11.32 microduplication in a patient with keratosis pilaris and intellectual disability.

Am J Med Genet A 2018 11 23;176(11):2395-2403. Epub 2018 Sep 23.

Laboratory of Cytogenetics, Research Institute of Medical Genetics, Tomsk NRMC, Tomsk, Russia.

The application of array-based comparative genomic hybridization and next-generation sequencing has identified many chromosomal microdeletions and microduplications in patients with different pathological phenotypes. Different copy number variations are described within the short arm of chromosome 18 in patients with skin diseases. In particular, full or partial monosomy 18p has also been associated with keratosis pilaris. Read More

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http://dx.doi.org/10.1002/ajmg.a.40478DOI Listing
November 2018
49 Reads
2.160 Impact Factor

Skin diseases associated with atopic dermatitis.

Clin Dermatol 2018 Sep - Oct;36(5):631-640. Epub 2018 Jun 1.

Department of Dermatology, Mt Sinai West, Icahn School of Medicine at Mt Sinai, New York, NY. Electronic address:

Atopic dermatitis is a common chronic pruritic inflammatory skin disorder, characterized by an abnormal skin barrier, immune dysfunction, and an altered skin microbiome. Atopic dermatitis may be seen in conjunction with a variety of other skin disorders due to the complex pathogenesis of atopic dermatitis, involving genetic and environmental factors that are associated with immune dysfunction, barrier defects, and altered skin microbiomes. Skin disorders associated with atopic dermatitis include diseases sharing similar genetic origins like ichthyosis vulgaris, infectious diseases such as impetigo, and eczema herpeticum, in addition to the cutaneous autoimmune diseases, alopecia areata, and vitiligo. Read More

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http://dx.doi.org/10.1016/j.clindermatol.2018.05.004DOI Listing
January 2019
21 Reads

Widespread keratosis pilaris in a patient with Noonan syndrome with multiple lentigines.

Int J Dermatol 2018 11 27;57(11):e140-e141. Epub 2018 Aug 27.

Department of Dermatology, University of Health Sciences, Ankara Numune Training and Research Hospital, Ankara, Turkey.

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http://doi.wiley.com/10.1111/ijd.14209
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http://dx.doi.org/10.1111/ijd.14209DOI Listing
November 2018
14 Reads

Effectiveness of photopneumatic technology: a descriptive review of the literature.

Lasers Med Sci 2018 Nov 24;33(8):1631-1637. Epub 2018 Aug 24.

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1475 NW 12th Ave., 2nd Floor, Unit 2099, Sylvester Comprehensive Cancer Center, Miami, FL, 33136, USA.

Usage of photopneumatic technology has recently increased for treatment of different skin conditions such as acne, keratosis pilaris (KP), and rosacea. Photopneumatic devices combine gentle negative pressure with broad band pulsed light simultaneously to attack multiple targets in the skin for better treatment outcomes. In this literature review, we evaluate the efficacy of photopneumatic therapy on treatment of acne, keratosis pilaris (KP), and rosacea. Read More

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http://link.springer.com/10.1007/s10103-018-2619-1
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http://dx.doi.org/10.1007/s10103-018-2619-1DOI Listing
November 2018
52 Reads

Dermatological manifestations in cardiofaciocutaneous syndrome: a prospective multicentric study of 45 mutation-positive patients.

Br J Dermatol 2019 01 30;180(1):172-180. Epub 2018 Sep 30.

Department of Clinical Genetics, Arnaud de Villeneuve Hospital, University of Montpellier, Montpellier, France.

Background: Data on dermatological manifestations of cardiofaciocutaneous syndrome (CFCS) remain heterogeneous and almost without expert dermatological classification.

Objectives: To describe the dermatological manifestations of CFCS; to compare them with the literature findings; to assess those discriminating CFCS from other RASopathies, including Noonan syndrome (NS) and Costello syndrome (CS); and to test for dermatological phenotype-genotype correlations.

Methods: We performed a 4-year, large, prospective, multicentric, collaborative dermatological and genetic study. Read More

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http://doi.wiley.com/10.1111/bjd.17077
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http://dx.doi.org/10.1111/bjd.17077DOI Listing
January 2019
9 Reads

Linear atrophoderma of Moulin: A rare entity.

Indian J Dermatol Venereol Leprol 2018 Sep-Oct;84(5):591-594

Department of Dermatology, Seth G. S. Medical College and KEM Hospital, Mumbai, Maharashtra, India.

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http://dx.doi.org/10.4103/ijdvl.IJDVL_136_17DOI Listing
August 2019
4 Reads

Mutation and expression of ABCA12 in keratosis pilaris and nevus comedonicus.

Mol Med Rep 2018 Sep 31;18(3):3153-3158. Epub 2018 Jul 31.

Department of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.

Keratosis pilaris (KP) and nevus comedonicus (NC) are congenital keratinized dermatoses; however, the exact etiology of these two diseases is unclear. The objective of the present study was to identify the disease‑causing genes and their association with functional alterations in the development of KP and NC. Peripheral blood samples of one KP family, two NC families and 100 unrelated healthy controls were collected. Read More

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http://www.spandidos-publications.com/10.3892/mmr.2018.9342
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http://dx.doi.org/10.3892/mmr.2018.9342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102636PMC
September 2018
18 Reads

Keratosis Pilaris and its Subtypes: Associations, New Molecular and Pharmacologic Etiologies, and Therapeutic Options.

Am J Clin Dermatol 2018 Oct;19(5):733-757

The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, 240 East 38th Street, 11th Floor, New York, NY, 10016, USA.

Keratosis pilaris is a common skin disorder comprising less common variants and rare subtypes, including keratosis pilaris rubra, erythromelanosis follicularis faciei et colli, and the spectrum of keratosis pilaris atrophicans. Data, and critical analysis of existing data, are lacking, so the etiologies, pathogeneses, disease associations, and treatments of these clinical entities are poorly understood. The present article aims to fill this knowledge gap by reviewing literature in the PubMed, EMBASE, and CINAHL databases and providing a comprehensive, analytical summary of the clinical characteristics and pathophysiology of keratosis pilaris and its subtypes through the lens of disease associations, genetics, and pharmacologic etiologies. Read More

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http://link.springer.com/10.1007/s40257-018-0368-3
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http://dx.doi.org/10.1007/s40257-018-0368-3DOI Listing
October 2018
85 Reads
2.520 Impact Factor

Exacerbation of ichthyosis vulgaris phenotype by co-inheritance of STS and FLG mutations in a Chinese family with ichthyosis: a case report.

BMC Med Genet 2018 07 18;19(1):120. Epub 2018 Jul 18.

Department of Rehabilitation, Zhongnan Hospital of Wuhan University, Wuhan, 430000, China.

Background: X-linked ichthyosis (XLI) is a recessive keratinization condition caused by deficient activity of steroid-sulfatase due to mutations in steroid sulfatase (STS) gene located on the X chromosome. In contrast, ichthyosis vulgaris (IV) is caused by filaggrin deficiency due to semi-dominant loss-of-function mutations of filaggrin (FLG) gene. Filaggrin defects could synergize with XLI to exacerbate its phenotype. Read More

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http://dx.doi.org/10.1186/s12881-018-0642-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052571PMC
July 2018
5 Reads

Desmoglein 4 Mutation Underlies Autosomal Recessive Keratosis Pilaris Atrophicans.

Acta Derm Venereol 2018 Aug;98(8):809-810

Department of Dermatology, "Emek" Medical Center, Afula, Israel.

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http://dx.doi.org/10.2340/00015555-2976DOI Listing
August 2018
42 Reads

Recurrent and Fixed Neutrophilic Dermatosis Associated With Dasatinib.

J Cutan Med Surg 2018 Nov/Dec;22(6):621-623. Epub 2018 May 13.

4 Division of Clinical Dermatology and Cutaneous Science, Department of Medicine, Dalhousie University, Halifax, NS, Canada.

Background: Dasatinib is a tyrosine kinase inhibitor indicated for the treatment of chronic myeloid leukemia (CML). Skin rashes are common, occurring in about a quarter of patients treated, and are generally mild. The commonest rash is a keratosis pilaris-like eruption. Read More

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http://journals.sagepub.com/doi/10.1177/1203475418775663
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http://dx.doi.org/10.1177/1203475418775663DOI Listing
January 2019
13 Reads

Chlorine Dioxide Complex Cleanser: A New Agent With Rapid Efficacy for Keratosis Pilaris.

J Drugs Dermatol 2018 May;17(5):554-556

Chlorine dioxide complex™ is a new molecule to dermatology that is a unique, non-toxic, broad spectrum anti-microbial and keratolytic compound. Chlorine dioxide has been used as an antiseptic in industrial settings for decades, primarily in water treatment facilities for municipal water supplies and food preparation. The compound has exceptional antiseptic properties with no known potential for development of resistance. Read More

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May 2018
26 Reads