Exp Eye Res 2022 Jun 4;219:109059. Epub 2022 Apr 4.
Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, College of Medicine, Chicago, IL, USA; Department of Microbiology and Immunology, University of Illinois at Chicago, College of Medicine, Chicago, IL, USA. Electronic address:
Herpes Simplex Virus-1 (HSV-1) is a neurotropic virus that can infect humans in the eye and travel to the trigeminal ganglion to establish latency. HSV-1 causes various disease states in both the primary and secondary sites of infection including the eye and the nervous system. This DNA virus exploits various adaptive measures to infect host cells, hijack host cell proteins, evade host immune response and spread from cell-to-cell to avoid immune detection. Read More