707 results match your criteria Kasabach-Merritt Syndrome
Genet Med 2018 Nov 9. Epub 2018 Nov 9.
Department of Obstetrics, Gynecology, & Reproductive Sciences, University of California, San Francisco, CA, USA.
Purpose: Numerous etiologies may lead to nonimmune hydrops fetalis (NIHF), and the underlying cause often remains unclear. We aimed to determine the proportion of NIHF cases in which the etiology was clearly determined in a large, contemporary, and diverse cohort, as well as to describe the etiologies with a focus on genetic causes.
Methods: Retrospective review of NIHF cases between 2015 and 2017 from the five University of California Fetal-Maternal Consortium sites. Read More
Turk J Haematol 2018 Oct 22. Epub 2018 Oct 22.
Turk J Pediatr 2018 ;60(2):188-190
Molecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Sepaskhah M, Hajizadeh J, Sari-Aslani F, Jowkar F. Tufted angioma arising at the site of hepatitis B vaccination: A case report. Turk J Pediatr 2018; 60: 188-190. Read More
JAAD Case Rep 2018 Oct 3;4(9):893-895. Epub 2018 Oct 3.
Division of Dermatology, Medical College of Georgia at Augusta University, Augusta, Georgia.
J Cancer Res Clin Oncol 2018 Dec 6;144(12):2475-2484. Epub 2018 Oct 6.
Department of Vascular and Interventional Radiology, Chengdu Women and Children's Central Hospital, Chengdu, 610031, China.
Purpose: We sought to characterize the clinical features and management of patients diagnosed as Kaposiform hemangioendothelioma (KHE) without cutaneous involvement.
Methods: The electronic patient chats at six Triple A hospitals in China were searched to find all patient diagnoses with KHE without cutaneous involvement.
Results: Of 30 patients (mean age at diagnosis, 55. Read More
Cancer Manag Res 2018 7;10:3325-3331. Epub 2018 Sep 7.
Department of Vascular and Interventional Radiology, Chengdu Women and Children's Central Hospital, Chengdu, China.
Purpose: Musculoskeletal complications have been associated with kaposiform hemangioendothelioma (KHE) and can lead to disability and reduced quality of life. We aimed to determine the clinical characteristics of musculoskeletal complication in patients with KHE without Kasabach-Merritt phenomenon (KMP) in order to identify features that may aid clinicians in KHE treatment.
Patients And Methods: We conducted a cohort study of KHE without KMP associated with musculoskeletal complication between January 2006 and February 2017 at three tertiary medical centers in China. Read More
J Dermatol 2018 Oct 17;45(10):1203-1206. Epub 2018 Aug 17.
Division of Oncology, Department of Pediatric Surgery, West China Hospital of Sichuan University, Chengdu, China.
Kasabach-Merritt phenomenon (KMP) occurred uniquely in patients with kaposiform hemangioendothelioma (KHE) and tufted angioma (TA). We report the clinical characteristics of two patients with KHE involving the right upper arm. The patients demonstrated rapid enlargement of the lesion with severe KMP shortly after vaccination. Read More
Clin Chim Acta 2018 Nov 7;486:199-204. Epub 2018 Aug 7.
Department of Hemangioma and Vascular Malformation Surgery, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, 7 Weiwu Road, Zhengzhou 450003, China. Electronic address:
Objective: To analyze the clinical characteristics and treatment of pediatric tufted angiomas(TA)complicated by Kasabach-Merritt Phenomenon (KMP).
Method: A retrospective analysis was conducted on the clinical data and follow-up data of 13 patients diagnosed with TA complicated by KMP. Five male and 8 female patients with an average age of 5. Read More
Pediatr Int 2018 Sep 8;60(9):887-889. Epub 2018 Aug 8.
Department of Pediatrics, Gifu University Graduate School of Medicine, Yanagido, Japan.
Pediatr Blood Cancer 2018 Dec 1;65(12):e27305. Epub 2018 Aug 1.
Department of Pediatric Hematology/Oncology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania.
A full-term newborn with kaposiform hemangioendothelioma (KHE) affecting the right thigh with thrombocytopenia due to Kasabach-Merritt phenomenon (KMP) was referred to our center. After biopsy, he rapidly evolved to severe thrombocytopenia and severe coagulopathy. Standard therapy was initiated with prednisolone and vincristine. Read More
J Pediatr Hematol Oncol 2018 Oct;40(7):536-540
Department of Pediatric Cardiology, Advocate Children's Hospital, Oak Lawn.
Introduction: Kaposiform hemangioendothelioma (KHE) is a rare and aggressive vascular tumor that can be associated with a consumptive coagulopathy and thrombocytopenia (Kasabach-Merritt phenomenon). Only one case of an intracardiac KHE has been reported which was treated with surgical excision and then expectant management.
Case Presentation: We present a patient with an intracardiac KHE which presented as a large mass surrounding the atria, pulmonary veins, superior vena cava, and infiltrating the atrial septum with moderate compression of the superior vena cava and mild compression of the pulmonary veins. Read More
World J Pediatr 2018 08 27;14(4):322-329. Epub 2018 Jul 27.
Pediatric Surgery, Dr. von Hauner Childen's Hospital, Ludwig-Maximilians University of Munich, Munich, Germany.
Background: Kaposiform hemangioendothelioma (KHE) is a rare vascular tumor affecting infants and young children. Although benign, it can be associated with an aggressive locally growing tumor and/or a life-threatening Kasabach-Merritt phenomenon (KMP). To date, only reviews of limited cases have been performed. Read More
J Pediatr Hematol Oncol 2018 Jul 23. Epub 2018 Jul 23.
Paediatrics, Division of Haematology/Oncology.
Kaposiform hemangioendothelioma (KHE) is a rare infiltrative vascular tumor that may be associated with Kasabach-Merritt Phenomenon (KMP), which is a consumptive coagulopathy with potentially life-threatening thrombocytopenia. Management of KHE and KMP is challenging, and currently, there are no standardized validated treatment protocols. Mammalian target of rapamycin inhibitors have been shown to be effective in the treatment of KHE. Read More
Mediterr J Hematol Infect Dis 2018 1;10(1):e2018043. Epub 2018 Jul 1.
Pediatric Hematology Oncology, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
Background: Kaposiform Hemangioendothelioma (KHE) is a rare vascular tumour of the infancy and the first decade of life. It is locally aggressive and potentially life threatening when associated with consumptive coagulopathy, known as Kasabach-Merritt syndrome (KMS). No consensus or guideline for the therapy has been reached because of the lack of prospective trials, and the different standard care suggestions are based on retrospective case series. Read More
Pediatr Dermatol 2018 Sep 12;35(5):635-638. Epub 2018 Jul 12.
Department of Pediatric Surgery, Second Affiliated Hospital, Medical College of Xi'an, JiaoTong University, Xi'an, China.
Background: Sirolimus has been used to manage various complex vascular anomalies. Kaposiform hemangioendothelioma and tufted angioma may develop Kasabach-Merritt phenomenon in infancy.
Methods: We retrospectively reviewed the clinical and laboratory data of eight patients with kaposiform hemangioendothelioma and tufted angioma who were initially treated using oral sirolimus in our center, including six with Kasabach-Merritt phenomenon. Read More
J Neonatal Perinatal Med 2018 ;11(2):209-213
Kasabach-Merritt syndrome is a rare life-threatening clinical presentation in neonatal period. it is characterized by giant hemangioma and serious thrombocytopenia. The diagnostic criteria include: 1) hemangiomas on skin, 2) thrombocytopenia or coagulopathy, 3) hemangioma on internal organs diagnosed by ultrasonography, computed tomography or magnetic resonance imaging, and 4) excluding reasons, such as idiopathic thrombocytopenic purpura or hypersplenism. Read More
Ann Hepatol 2018 July - August ,;17(4):655-660
Department of Internal Medicine, Division of Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan.
A 76-year-old woman was referred to our hospital due to massive gingival bleeding following teeth extraction. Laboratory findings suggested disseminated intravascular coagulopathy (DIC). Enhanced computed tomography and magnetic resonance imaging disclosed multiple hypervascular liver masses of 2-6 cm in diameter, the largest of which displaying an irregular enhancement pattern. Read More
Rare Tumors 2018 30;10:2036361318776185. Epub 2018 May 30.
Department of Pediatrics, Kinki University Faculty of Medicine, Osaka-Sayama, Japan.
We describe our experience with a 12 year-old girl with kaposiform hemangioendothelioma accompanied by Kasabach-Merritt phenomenon with exacerbation of the disease 10 years after the initial diagnosis. Kaposiform hemangioendothelioma infiltrated into the subcutaneous tissue of the facial skin with deterioration of coagulopathy despite conventional therapies including corticosteroid, vincristine, and propranolol. Sirolimus, a mammalian target of rapamycin inhibitor, produced rapid and dramatic improvement of the Kasabach-Merritt phenomenon and kaposiform hemangioendothelioma shrinkage. Read More
Clin J Gastroenterol 2018 Oct 29;11(5):411-416. Epub 2018 May 29.
Department of Gastroenterology, National Hospital Organization Kanazawa Medical Center, 1-1 Shimoishibikicho, Kanazawa, Ishikawa, 920-8650, Japan.
Since diffuse hepatic hemangiomatosis (DHH) is an extremely rare disease especially in adults, the etiology and natural course of adult-onset DHH has not been well understood. We report a case of DHH complicated with multiple organic dysfunction and Kasabach-Merritt syndrome (KMS) in an 83-year-old female. She presented with mild abdominal distension and laboratory findings revealed thrombocytopenia and abnormal coagulation, indicating disseminated intravascular coagulation (DIC). Read More
J Med Ultrason (2001) 2018 Oct 10;45(4):653-656. Epub 2018 Apr 10.
Department of Radiology, Loyola University Medical Center, Maywood, IL, USA.
Kaposiform hemangioendothelioma (KHE) is a rare vascular tumor of early childhood and infancy. Kasabach-Merritt phenomenon, a common complication of KHE, is characterized by life-threatening thrombocytopenia, hemolytic anemia, and consumption coagulopathy. There may be atypical cases that do not present with Kasabach-Merritt phenomenon and do have atypical imaging findings. Read More
An Pediatr (Barc) 2018 May 4;88(5):292-293. Epub 2018 Apr 4.
Servicio de Pediatría, Hospital Dr. José Molina Orosa, Lanzarote, Las Palmas, España.
Pediatrics 2018 Apr;141(Suppl 5):S425-S429
Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital and School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Kaposiform hemangioendothelioma (KHE) is a rare infiltrative vascular tumor that is potentially life-threatening when presenting with Kasabach-Merritt phenomenon (KMP). KMP is clinically characterized as severe thrombocytopenia and hypofibrinogenemia and therefore is associated with a high mortality rate. There is no standard of cure for KHE currently. Read More
Pediatrics 2018 Apr;141(Suppl 5):S421-S424
Departments of Pediatrics and
Sirolimus is an effective therapy for children with kaposiform hemangioendothelioma with or without the Kasabach-Merritt phenomenon. We report the case of a child with kaposiform hemangioendothelioma and the Kasabach-Merritt phenomenon who developed pneumonia (PCP) while on sirolimus and a prednisolone taper, after lack of adequate response to prednisolone, propranolol, and vincristine. He had a prompt positive clinical and laboratory response to sirolimus, but 4 weeks after starting it, at the age of 4 months, he developed PCP. Read More
Br J Dermatol 2018 Aug 24;179(2):457-463. Epub 2018 Apr 24.
Vascular Biology Program and Department of Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.
Background: Few studies have reported the clinical features, complications and predictors of Kasabach-Merritt phenomenon (KMP) associated with Kaposiform haemangioendothelioma (KHE).
Objectives: To determine the clinical characteristics present at diagnosis and to identify features that may aid clinicians in managing KHE.
Methods: We conducted a cohort study of 146 patients diagnosed with KHE. Read More
Bull Cancer 2018 Jun 20;105(6):610-625. Epub 2018 Mar 20.
Centre de référence des maladies rares de la peau d'origine génétique, hôpital Pellegrin-Enfants, centre hospitalier universitaire de Bordeaux, unité de dermatologie pédiatrique, 33076 Bordeaux cedex, France.
Superficial vascular anomalies constitute a large group of malformative and tumoral conditions developed from all types of vessels. Vascular tumors are the result of cellular hyperplasia, whereas vascular malformations (VMs) are constituted of dysplastic vessels. The classification from International Society for the Study of Vascular Anomalies (ISSVA) is based on this pathogenic difference. Read More
Am J Dermatopathol 2018 Apr;40(4):231-239
Professor, Department of Dermatology, Mayo Clinic, Rochester, MN.
Vascular tumors in infants present a diagnostic and treatment dilemma for both clinicians and pathologists. Infantile hemangioma, the most common vascular tumor in infants, can be confused for other less common vascular tumors in infants. Correct and timely diagnosis is important, as some vascular tumors can be associated with life-threatening coagulopathy. Read More
Pediatr Dev Pathol 2018 03 16:1093526618765039. Epub 2018 Mar 16.
1 Department of Pathology and Laboratory Medicine, 14524 Phoenix Children's Hospital , Phoenix, Arizona.
Infantile choriocarcinoma (ICC) is a rare, highly malignant form of gestational trophoblastic neoplasia. Rapid diagnosis and initiation of treatment are paramount in reaching a successful outcome. Patients with these tumors typically present with a triad of anemia, hepatomegaly, and precocious puberty. Read More
Br J Radiol 2018 Jun 20;91(1086):20170798. Epub 2018 Mar 20.
3 Department of Radiology, Fudan University Shanghai Cancer Center , Shanghai , China.
Objective: Kaposiform hemangioendothelioma (KHE) is a unique locally aggressive vascular tumor with poor prognosis. The aim of this study is to assess the clinical and imaging features of KHE, and to compare the differences between solitary and diffusive infiltrative subtype further.
Methods: The clinical and radiological findings of a cohort of 25 cases with histologically proven KHE, between June 2011 and June 2016, were reviewed retrospectively. Read More
Turk J Haematol 2018 08 2;35(3):204-205. Epub 2018 Feb 2.
Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Department of General Medicine, Pondicherry, India
Br J Dermatol 2018 May 25;178(5):1213-1214. Epub 2018 Mar 25.
Department of Dermatology and Venereology, Capital Institute of Pediatrics, No. 2 YaBao Street, ChaoYang District, Beijing, 100020, China.
J Dermatol 2018 May 21;45(5):580-583. Epub 2018 Jan 21.
Guangzhou Women and Children's Medical Center, Guangzhou Medical University, China.
Vascular tumors associated with Kasabach-Merritt phenomenon (KMP) are life-threatening and the mortality is as high as 10-30%. Steroids are considered the primary choice for drug therapy. However, there are many steroid-resistant cases. Read More
Exp Ther Med 2017 Dec 18;14(6):6164-6168. Epub 2017 Oct 18.
Department of Hematology and Oncology of Children's Medical Center, Hunan Provincial People's Hospital, Changsha, Hunan 410005, P.R. China.
The present case report presented the diagnosis and treatment course of an infant diagnosed with Kasabach-Merritt syndrome (KMS) combined with hypercalcemia (HC). A 35-day-old infant with swelling on the upper right arm for >1 month and thrombocytopenia for 1 day was admitted to Hunan Provincial People's Hospital (Changsha, China) and a series of treatments, including γ-globulin impact, heparin anticoagulation, platelet transfusion, supplement of cryoprecipitate and fibrinogen following heparinization and inhabitation of vascular endothelial cell proliferation by propranolol, were performed. At 2 months after the initial admission to the hospital, surgery was conducted and the hemangioma was removed through pipeline arteriosclerosis embolization when the patient was hospitalized again with symptoms of vomiting and atrophy accompanied by HC. Read More
Pediatr Dermatol 2018 Jan 20;35(1):e92-e93. Epub 2017 Dec 20.
Department of Plastic and Oral Surgery, Harvard Medical School, Boston Children's Hospital, Boston, MA, USA.
Kaposiform hemangioendotheliomas are pediatric vascular tumors that do not metastasize. We present a patient with a thigh kaposiform hemangioendothelioma successfully treated using a systemic corticosteroid during infancy who was diagnosed with lymphedema in the extremity 9 years later. The observation that extremity kaposiform hemangioendothelioma could possibly be associated with lymphedema has implications for the care of patients with kaposiform hemangioendothelioma. Read More
J Pediatr Hematol Oncol 2018 May;40(4):e239-e242
Division of Hematology.
Kaposiform hemangioendothelioma (KHE) is a rare vascular tumor characterized by aggressive local invasion and a syndrome of platelet trapping known as Kasabach-Merritt phenomenon that, through deposition of platelet derived growth factors, may perpetuate the growth of the tumor. Although many cases of KHE are successfully treated with local control or low-intensity chemotherapy, some cases are often refractory even to aggressive treatment. Herein, we describe a patient with a refractory, recurrent KHE despite multiple attempts at local control and intensive chemotherapy, that ultimately was successfully treated with rationally designed and low-intensity combination therapy of sirolimus and aspirin. Read More
Chirurg 2018 Mar;89(3):245-254
Klinik und Poliklinik für Gefäßchirurgie und Endovaskuläre Chirurgie, Universitätsklinikum, Universität zu Köln, Kerpener Str. 62, 50937, Köln, Deutschland.
Vascular anomalies represent a spectrum of structural disorders and inborn errors of vascular morphogenesis, which may affect the entire arterial and venous vascular tree. They are divided into two major categories: tumors, which exhibit endothelial hyperplasia and malformations, which have normal endothelial turnover unless disturbed. Depending on their nature and complexity they can range from a simple "birthmark" to life-threatening entities. Read More
Clujul Med 2017 20;90(4):396-400. Epub 2017 Oct 20.
Department of Dermatology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Objectives: The aim of the study was to describe the historical and clinical characteristics of hemangiomas in a series of cases of our clinic.
Methods: This is a retrospective study of 36 patients with infantile hemangiomas consulted in our clinic.
Results: We had 14 multiple hemangiomas, and 1 kaposiform hemangioendothelioma. Read More
J Med Case Rep 2017 Oct 27;11(1):308. Epub 2017 Oct 27.
Pediatric Clinic, Institute for Childhood Diseases, Clinical Centre of Montenegro, Podgorica, Montenegro.
Background: Kasabach-Merritt syndrome represents the association of hemangioma with thrombocytopenia and consumptive coagulopathy. We present a case of Kasabach-Merritt syndrome treatment with orally administered propranolol.
Case Presentation: A 4. Read More
Case Rep Oncol 2017 Sep-Dec;10(3):863-870. Epub 2017 Sep 21.
Department of Clinical Oncology, Aichi Cancer Center Hospital, Nagoya, Japan.
Angiosarcoma of the heart is an uncommon soft tissue sarcoma. A few cases of disseminated intravascular coagulation (DIC) associated with angiosarcoma occurring in various organs, but not the heart, have been reported. Although taxane is commonly used in the treatment of metastatic angiosarcoma, data on the efficacy of nab-paclitaxel for angiosarcoma are limited. Read More
Vaccine 2017 12 16;35(48 Pt B):6594-6597. Epub 2017 Oct 16.
Department of Cardiac Surgery, The Children's Hospital of Zhejiang University School of Medicine, Zhejiang, China. Electronic address:
Kasabach-Merritt phenomenon (KMP) is a rare potentially life-threatening consumptive coagulopathy characterized by thrombocytopenia and hypofibrinogenemia occurring associated with the vascular tumors kaposiform hemangioendothelioma (KHE) and tufted angioma (TA). A 10-month old male infant, diagnosed with KHE on his left leg, underwent a rapid increase of the lesion and severe thrombocytopenia, one day after the first dose of inactivated Japanese encephalitis (JE) vaccination. The episode of KMP was treated successfully by steroid. Read More
Medicine (Baltimore) 2017 Sep;96(37):e6974
Department of Pediatric Surgery, Seoul National University College of Medicine, Seoul, Korea.
Rationale: Kaposiform hemangioendothelioma (KHE) is an aggressive vascular tumor, mainly occurring in infants and young children and previously reported cases were mainly cutaneous or visceral form. Intestinal kaposiform hemangioma was first reported in 2012. Intestinal type KHE showed better prognosis if the lesion was limited in the gastrointestinal tract and coagulopathy was not accompanied. Read More
Zhonghua Er Ke Za Zhi 2017 Sep;55(9):700-704
Department of Neurology, Children's Hospital Affiliated to Capital Institute of Paediatrics, Beijing 100020, China.
To analyze the clinical value of sirolimus plus prednisone for the treatment of the refractory kaposiform hemangioendothelioma(RKHE) and Kasabach-Merritt syndrome(KMS). Clinical retrospective analysis was carried out for 10 patients recruited in Children's Hospital Affiliated to Capital Institute of Paediatrics from January 2014 to January 2017 who were non responders to or relapsers after the treatment of propranolol, prednisone, pingyangmycin and lauromacrogol(5 cases RKHE, 5 cases RKHE plus KMS, age ranged from 6 days to 9 years); patients were treated with sirolimus at the dosage of 0.035 ml/(kg·d), once a day, for 6-410 days; the diagnosis of 10 patients were confirmed by pathological biopsy and immunohistochemical examination(IHC); the difference of the coagulation parameters and the platelet counts, the size of tumor and ecchymosis at different stages of treatment were recorded and measured by scale and ultrasonography; the side effects of sirolimus were recorded as well. Read More
Hautarzt 2017 Oct;68(10):790-795
Abt. Pädiatrische Dermatologie/Allergologie, Kath. Kinderkrankenhaus Wilhelmstift, Liliencronstr. 130, 22149, Hamburg, Deutschland.
Congenital and acquired vascular anomalies are common in childhood. In addition to predominantly harmless vascular skin alterations there are others which must be immediately treated due to the potentially threatening complications. As examples three anomalies and the typical complications are presented. Read More
Br J Dermatol 2018 Feb 21;178(2):e114-e116. Epub 2017 Dec 21.
Department of Dermatology and Reference Centre for Genodermatoses and Rare Skin Diseases (MAGEC), Université Paris Descartes - Sorbonne Paris Cité, INSERM U1163, Institut Imagine, Paris, France.
J Dermatol 2017 Dec 3;44(12):1389-1391. Epub 2017 Aug 3.
Department of Dermatology, Faculty of Medicine, Mie University, Tsu, Japan.
A male fetus was delivered by cesarean section with a large hemangioma on his right chest and thrombocytopenia. Clinically, Kasabach-Merritt syndrome (KMS) was suspected, and immediately he was treated with daily prednisolone (PSL) 1 mg/kg and recombinant thrombomodulin without response. Additional propranolol (1-3 mg/kg per day) and increased PSL 2 mg/kg per day therapy successfully controlled his disseminated intravascular coagulation and decreased the tumor size without serious side-effects. Read More
Medicine (Baltimore) 2017 Aug;96(31):e7688
Department of Hepatobiliary Surgery, China-Japan Friendship Hospital, Beijing, China.
Rationale: Adult Kasabach-Merritt syndrome associated with giant liver hemangioma is rare; to date, most reports have been single-case reports, and no multi-case reports or literature reviews are available.
Diagnoses: We conducted a retrospective analysis of 5 cases of adult Kasabach-Merritt syndrome associated with giant liver hemangioma treated at our hospital between 2011 and 2016. All 5 patients had varying severities of leukopenia, anemia, thrombocytopenia, prolonged prothrombin time, and hypofibrinogenemia. Read More
European J Pediatr Surg Rep 2017 Jan 28;5(1):e32-e35. Epub 2017 Jul 28.
Division of Vascular Anomalies, Department of Pediatric Surgery, La Paz Children's Hospital, Madrid, Spain.
Kaposiform hemangioendothelioma (KHE) is a vascular tumor frequently associated with Kasabach-Merritt phenomenon (KMP), characterized by severe thrombocytopenia and consumptive coagulopathy. Visceral involvement in KHE is rare. In our recent experience, sirolimus has shown to be an effective treatment in cutaneous KHE, becoming indeed the treatment of choice in KMP. Read More
Br J Haematol 2017 10 17;179(1). Epub 2017 Jul 17.
Department of Dermatology and Venereology, Capital Institute of Paediatrics, Beijing, China.
Clin Exp Dermatol 2017 Oct 13;42(7):825-827. Epub 2017 Jul 13.
Department of Paediatric Dermatology, Bristol Royal Hospital for Children, Bristol, UK.
Am J Case Rep 2017 Jun 19;18:682-686. Epub 2017 Jun 19.
Department of Medical Imaging, Changhua Christian Hospital, Changhua, Taiwan.
BACKGROUND Kasabach-Merritt syndrome is a potentially fatal disease that consists of hemangioma(s) with thrombocytopenia, microangiopathic hemolytic anemia, and coagulopathy. Extensive hemangiomatosis is rare. We present the radiological features and treatment strategy of a young adult suffering from Kasabach-Merritt syndrome with widespread hemangiomas and an infected huge hematoma in the right thigh. Read More