694 results match your criteria Kasabach-Merritt Syndrome


Giant Liver Hemangiomas: A Plea for Early Surgical Referral and Resection.

Case Rep Surg 2020 16;2020:5923787. Epub 2020 Jun 16.

School of Medicine and Hume-Lee Transplant Center, Virginia Commonwealth University, Richmond, Virginia 23298, USA.

Hepatic hemangiomas are the most common benign hepatic tumor. Current guidelines recommend surveillance imaging and reserving surgical intervention for symptomatic patients with giant liver hemangiomas (>5 cm). We present the case of a patient with a rapidly enlarging giant hepatic hemangioma initially managed by surveillance. Read More

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http://dx.doi.org/10.1155/2020/5923787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315262PMC

Erratum: Kasabach-Merritt syndrome with large cutaneous vascular tumors.

Authors:

J Indian Assoc Pediatr Surg 2020 May-Jun;25(3):192. Epub 2020 Apr 11.

[This corrects the article on p. 33 in vol. 17, PMID: 22279364. Read More

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http://dx.doi.org/10.4103/0971-9261.282164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302459PMC

Massive liver haemangioma causing Kasabach-Merritt syndrome in an adult.

Ann R Coll Surg Engl 2020 Jun 15:e1-e4. Epub 2020 Jun 15.

Mount Lebanon Hospital, Mount Lebanon, Lebanon.

Liver haemangiomas are common, but their size very rarely exceeds 40cm. Most people with liver haemangiomas are asymptomatic, and diagnosis is usually made incidentally during imaging for other complaints. When a liver haemangioma is symptomatic or produces complications, surgical intervention may be warranted. Read More

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http://dx.doi.org/10.1308/rcsann.2020.0146DOI Listing
June 2020
1.223 Impact Factor

Tangled Up in Red Cells: A Large Liver Mass with Intravascular Hemolysis.

Dig Dis Sci 2020 Jul;65(7):1960-1963

Division of Gastroenterology and Hepatology, University of New Mexico School of Medicine, Albuquerque, NM, 87131, USA.

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http://dx.doi.org/10.1007/s10620-020-06311-5DOI Listing

Bone Marrow Langerhans Cell Histiocytosis in Association with Kasabach-Merritt Syndrome: The Difficulty of a Differential Diagnosis.

Case Rep Oncol 2020 Jan-Apr;13(1):408-413. Epub 2020 Apr 14.

Department of Internal Medicine II, Professor Doutor Fernando Fonseca Hospital, Amadora, Portugal.

Langerhans cell histiocytosis is a rare haematological disorder with variable clinical findings and a high mortality rate. On the other hand, Kasabach-Merritt syndrome is of rare onset at adult age, requiring the simultaneous presentation of vascular lesion, thrombocytopenia, and consumptive coagulopathy. We present the first reported case of both diseases in a single patient and highlight the difficulties of diagnostic. Read More

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http://dx.doi.org/10.1159/000506539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184841PMC

Diffuse bone and soft tissue angiomatosis with GNAQ mutation.

Pathol Int 2020 Apr 20. Epub 2020 Apr 20.

Department of Translational Research and of New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.

We describe a unique case of skeletal and extraskeletal angiomatosis complicated by Kasabach-Merritt syndrome. The patient was a 3-year-old boy, who presented with involvement of both femurs and left tibia, as well as with soft tissue lesions of the left thigh. At birth, multiple hemangiomas of the soft tissues of the frontal and parietal scalp had been identified, together with a space-occupying lesion of the lung. Read More

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http://dx.doi.org/10.1111/pin.12933DOI Listing

Tufted angioma with Kasabach-Merritt syndrome: Two cases successfully treated with everolimus.

Pediatr Blood Cancer 2020 Jun 10;67(6):e28291. Epub 2020 Apr 10.

Department of Dermatology, Mohammed VI University Hospital Center, Cadi Ayyad University, Marrakech, Morocco.

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http://dx.doi.org/10.1002/pbc.28291DOI Listing

Diffused hepatic angiosarcoma with Kasabach-Merritt syndrome-case report and literature review.

BMC Gastroenterol 2020 Mar 30;20(1):80. Epub 2020 Mar 30.

Department of hepatobiliary surgery, Beijing Chaoyang Hospital, Capital Medical University, 8 Gongti South Street, Chaoyang, 100021, District Beijing, China.

Background: Hepatic angiosarcoma is a rare malignant tumor featured by highly aggressive behavior and poor prognosis. There are few reports about diffused hepatic angiosarcoma with Kasabach-Merritt syndrome till now.

Case Presentation: A male patient with the chief complain of hepatic space-occupying lesion accompanied by disturbance of consciousness and jaundice. Read More

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http://dx.doi.org/10.1186/s12876-020-01216-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104501PMC

Unexplained isolated acute severe thrombocytopenia after surgery for a recurrent malignant retroperitoneal tumor presenting with colon perforation: A case study of a disastrous complication.

Int J Surg Case Rep 2020 6;67:91-94. Epub 2020 Feb 6.

Department of General Surgery, General Hospital of Drama, Drama, Greece.

Introduction: Tumor- or treatment- induced thrombocytopenia in solid cancer patients is common. In the postoperative setting, diagnosis of thrombocytopenia become more complex as infection, sepsis, drugs and transfusion come also into the equation.

Presentation Of Case: Herein, the case an otherwise-healthy 71-year-old male patient with a sizable recurrent malignant retroperitoneal tumor under pazopanib admitted with colon perforation and submitted to emergency left colectomy with end transverse colostomy is presented. Read More

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http://dx.doi.org/10.1016/j.ijscr.2020.01.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015829PMC
February 2020

Successful treatment of a patient with Kasabach-Merritt syndrome and multiple giant hepatic hemangiomas.

J Int Med Res 2020 Jan;48(1):300060519898358

Department of Rheumatology and Immunology, Shanghai Changzheng Hospital, the Second Military Medical University, Shanghai, P.R. China.

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http://dx.doi.org/10.1177/0300060519898358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113715PMC
January 2020

Reply to: Comment on: Potential biomarkers of kaposiform lymphangiomatosis.

Pediatr Blood Cancer 2020 04 13;67(4):e28156. Epub 2020 Jan 13.

Department of Pediatrics, Graduate School of Medicine, Gifu University, Gifu, 501-1194, Japan.

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http://dx.doi.org/10.1002/pbc.28156DOI Listing

Neonatal consultations: vascular lumps, bumps, and tumors in the neonate.

Authors:
Minnelly Luu

Cutis 2019 Nov;104(5):260-262

Children's Hospital, Los Angeles, California, USA.

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November 2019

Comment on: Potential biomarkers of kaposiform lymphangiomatosis.

Pediatr Blood Cancer 2020 04 23;67(4):e28100. Epub 2019 Dec 23.

Division of Hematology/Oncology, Vascular Anomalies Center, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/pbc.28100DOI Listing

Bifocal Tibial Kaposiform Hemangioendothelioma Responsive to Vincristine Therapy: A Case Report.

Am J Case Rep 2019 Dec 23;20:1923-1929. Epub 2019 Dec 23.

Department of Special Surgery, School of Medicine, University of Jordan, Amman, Jordan.

BACKGROUND Kaposiform hemangioendothelioma is a rare locally aggressive vascular endothelial-derived spindle cells neoplasm. Herein, we report a rare case of bifocal tibial kaposiform hemangioendothelioma. CASE REPORT A 9-year-old female presented with a 2-year history of pain and swelling in the left leg. Read More

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http://dx.doi.org/10.12659/AJCR.917696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944038PMC
December 2019

Endothelial cell malignancies in infants, children and adolescents: Treatment results of three Cooperative Weichteilsarkom Studiengruppe (CWS) trials and one registry.

Pediatr Blood Cancer 2020 03 8;67(3):e28095. Epub 2019 Dec 8.

Department for Children and Adolescents, University of Frankfurt, Frankfurt am Main, Germany.

Background: Endothelial cell malignancies are extremely rare in childhood. New identification of genetic abnormalities (WWTR1:CAMTA1 translocation) helps to recognize potential therapeutic targets. Little is known about treatment and outcome of these patients. Read More

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http://dx.doi.org/10.1002/pbc.28095DOI Listing

Tufted angioma presenting with subclinical coagulopathy.

Dermatol Online J 2019 Sep 15;25(9). Epub 2019 Sep 15.

Department of Dermatology, Wake Forest Baptist Medical Center, Winston Salem, NC.

Tufted angioma is a rare, benign vascular tumor of uncertain pathogenesis, characterized histopathologically by "tufts" of capillaries within the dermis. A life-threatening coagulopathy, Kasabach-Merritt phenomenon, occurs in approximately 10% of cases of tufted angioma and is characterized by profound thrombocytopenia and fibrinogen consumption. We present an asymptomatic 10-month-old boy who presented with an erythematous patch of the right upper extremity and subsequently was diagnosed by biopsy with tufted angioma. Read More

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September 2019

Prenatally diagnosed congenital hemangioma with elevated middle cerebral artery peak systolic velocity mimicking the Kasabach-Merritt phenomenon: A case report.

J Obstet Gynaecol Res 2019 Dec 9;45(12):2456-2460. Epub 2019 Sep 9.

Department of Maternal Fetal Medicine, Osaka Women's and Children's Hospital, Osaka, Japan.

Congenital hemangioma is a rare vascular tumor that develops prenatally, and a large congenital hemangioma may be accompanied by the Kasabach-Merritt phenomenon. We present a case of prenatally diagnosed fetal congenital hemangioma through ultrasound and maternal anti-Jr(a) antibody alloimmunization with elevated middle cerebral artery peak systolic velocity. To investigate fetal anemia and hemostatic condition, we performed percutaneous umbilical blood sampling, which revealed no symptom of either Kasabach-Merritt phenomenon or sensitization to anti-Jr(a) antibody. Read More

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http://dx.doi.org/10.1111/jog.14121DOI Listing
December 2019
3 Reads

Sirolimus therapy for kaposiform hemangioendothelioma with long-term follow-up.

J Dermatol 2019 Nov 5;46(11):956-961. Epub 2019 Sep 5.

Department of Pediatric Surgery, Children's Hospital of Fudan University, Shanghai, China.

Mammalian target of rapamycin inhibitors have shown promising results in the management of kaposiform hemangioendothelioma (KHE). The purpose of this study was to present our experience involving sirolimus therapy for KHE. A retrospective study was conducted to review the medical documents of 26 patients with KHE who were treated with sirolimus at our hospital between March 2012 and December 2016. Read More

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http://dx.doi.org/10.1111/1346-8138.15076DOI Listing
November 2019

What is new in endothelial neoplasia?

Virchows Arch 2020 Jan 28;476(1):17-28. Epub 2019 Aug 28.

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, Boston, MA, USA.

The classification of vascular neoplasms continues to evolve as we accumulate more genetic and clinical data, particularly for rare tumor types. Because of tumor rarity, changes to classification schema, overlapping histologic features, and in some cases, lack of morphologic evidence of vasoformation, vascular neoplasms present a diagnostic challenge. Here, we discuss recent developments in our understanding of vascular tumors, with a detailed discussion of epithelioid hemangioma, tufted angioma, kaposiform hemangioendothelioma, composite hemangioendothelioma, pseudomyogenic hemangioendothelioma, epithelioid hemangioendothelioma, and angiosarcoma. Read More

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http://dx.doi.org/10.1007/s00428-019-02651-4DOI Listing
January 2020
1 Read

Successful treatment of cardiac haemangiomas with oral propranolol: a case series of two patients.

Eur Heart J Case Rep 2019 Jun;3(2)

Department of Paediatric Cardiology and Adult Congenital Heart Disease, Mitera Hospital, Erithrou Stavrou, Athens, Greece.

Background: Cardiac haemangiomas are extremely rare tumours with equivocal surgical outcomes. Haemangiomas appearing on other sites of the body have been successfully treated with oral propranolol. To the best of our knowledge, such treatment has not been tried to date for cardiac location of haemangiomas. Read More

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http://dx.doi.org/10.1093/ehjcr/ytz093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601147PMC
June 2019
5 Reads

Tufted angioma with associated Kasabach-Merritt phenomenon caused by somatic mutation in GNA14.

Pediatr Dermatol 2019 Nov 18;36(6):963-964. Epub 2019 Aug 18.

Department of Dermatology, Yale University School of Medicine, New Haven, CT, USA.

Tufted angioma (TA) is a rare vascular tumor characterized by histologic tufts of proliferating capillaries that occurs in infancy or early childhood, with a poorly understood pathogenesis. Though benign, TA can be associated with the Kasabach-Merritt phenomenon (KMP), a life-threatening consumptive coagulopathy and thrombocytopenia. Here, we explored the genetic mechanism underlying a case of TA associated with KMP via targeted sequencing of laser capture micro-dissected lesion and blood DNA, and identified a somatic, activating GNA14 mutation specific to the tumor. Read More

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http://dx.doi.org/10.1111/pde.13979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039697PMC
November 2019
2 Reads

Tacrolimus ointment for the treatment of superficial kaposiform hemangioendothelioma and tufted angioma.

J Dermatol 2019 Oct 2;46(10):898-901. Epub 2019 Aug 2.

Division of Oncology, Department of Pediatric Surgery, West China Hospital of Sichuan University, Chengdu, China.

Kaposiform hemangioendothelioma (KHE) and tufted angioma (TA) are rare infiltrative vascular tumors. Currently, no standard treatment regimens exist for KHE/TA. The purpose of our study was to evaluate the efficacy and safety of topical application of tacrolimus for superficial KHE/TA. Read More

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http://dx.doi.org/10.1111/1346-8138.15031DOI Listing
October 2019
1 Read

Ultrasonography and magnetic resonance imaging features of kaposiform hemangioendothelioma and tufted angioma.

J Dermatol 2019 Oct 2;46(10):835-842. Epub 2019 Aug 2.

Department of, Ultrasound, School of Medicine, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Kaposiform hemangioendothelioma (KHE) and tufted angioma (TA) primarily occurring in infants are difficult to distinguish. This study evaluated ultrasonography (US) and magnetic resonance imaging (MRI) features of KHE and TA. Pathologically proven TA (n = 21) and KHE (n = 40 [11 KHE + Kasabach-Merritt phenomenon [KMP]]) occurring between January 2015 and December 2017 were reviewed. Read More

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http://dx.doi.org/10.1111/1346-8138.15025DOI Listing
October 2019
3 Reads

A not so harmless mass: Kaposiform hemangioendothelioma complicated by a Kasabach-Merritt phenomenon.

Arch Pediatr 2019 Sep 25;26(6):365-369. Epub 2019 Jul 25.

Department of Neonatology, University Hospital Liège and University of Liège, Liège, Belgium.

A vascular mass localized in the face and the neck was displayed by ultrasonography in a 38-week-old male fetus. At birth, the mass was bulky and purplish. The newborn breathed spontaneously but with severe desaturation. Read More

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http://dx.doi.org/10.1016/j.arcped.2019.06.003DOI Listing
September 2019
1 Read

Giant Liver Hemangioma with Kasabach-Merritt Syndrome.

Am J Med 2020 01 9;133(1):56-57. Epub 2019 Jul 9.

Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minn.

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http://dx.doi.org/10.1016/j.amjmed.2019.06.024DOI Listing
January 2020
5 Reads

Kaposiform lymphangiomatosis and kaposiform hemangioendothelioma: similarities and differences.

Orphanet J Rare Dis 2019 07 5;14(1):165. Epub 2019 Jul 5.

Laboratory of Pathology, West China Hospital of Sichuan University, Chengdu, 610041, China.

Background: Kaposiform lymphangiomatosis (KLA) and kaposiform hemangioendothelioma (KHE) are rare and aggressive vascular disorders. The aim of this study was to examine the clinical features and prognosis of KLA and KHE involving the thorax.

Methods: The clinical features, imaging and pathological findings, treatments and outcome were retrospectively reviewed for 6 patients with KLA and 7 patients with KHE involving the thorax. Read More

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http://dx.doi.org/10.1186/s13023-019-1147-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612206PMC
July 2019
4 Reads
3.358 Impact Factor

Hepatobiliary and Pancreatic: Kasabach-Merritt syndrome in adult.

J Gastroenterol Hepatol 2019 Oct 28;34(10):1675. Epub 2019 May 28.

AW Morrow Gastroenterology and Liver Center, Royal Prince Alfred Hospital, Sydney, Australia.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jgh.14676
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http://dx.doi.org/10.1111/jgh.14676DOI Listing
October 2019
8 Reads

Kasabach-Merritt Syndrome in an Adult

Turk J Haematol 2020 Feb 23;37(1):53-54. Epub 2019 May 23.

Zvezdara University Medical Center, Department of Surgery, Belgrade, Serbia

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http://dx.doi.org/10.4274/tjh.galenos.2019.2019.0068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057747PMC
February 2020
6 Reads

A Rare Presentation of Sudden Death due to Pulmonary Thromboembolism Possibly as a Result of Giant Hepatic Hemangioma.

J Forensic Sci 2019 Nov 22;64(6):1921-1925. Epub 2019 May 22.

Department of Pathology, National University Hospital, National University Hospital (S) Pte Ltd, 5 Lower Kent Ridge Rd, Singapore, 119074, Singapore.

Hepatic hemangiomas are usually detected incidentally when investigating for other nonrelated pathologies. When symptomatic, they are usually large and cause symptoms such as abdominal discomfort or other digestive issues. Occasionally, uncommon presentations such as bleeding with coagulopathy (Kasabach-Merritt syndrome) or even fever of unknown origin may occur. Read More

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http://dx.doi.org/10.1111/1556-4029.14080DOI Listing
November 2019
13 Reads

Activation of Hedgehog Signaling in Aggressive Hepatic Hemangioma in Newborns and Infants.

Anticancer Res 2019 May;39(5):2351-2360

Department of Pediatric Surgery, Dr. von Hauner Children's Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.

Background/aim: Hepatic hemangiomas (HH) can show an aggressive course with significant complications. Prognostic markers that identify an aggressive course are entirely absent. Since we have showed that Hedgehog signaling is overexpressed in aggressive hemangiomas of the skin. Read More

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http://dx.doi.org/10.21873/anticanres.13352DOI Listing
May 2019
31 Reads

Low dose sirolimus treatment for refractory tufted angioma and congenital kaposiform hemangioendothelioma, both with Kasabach-Merritt phenomenon.

Pediatr Blood Cancer 2019 08 14;66(8):e27810. Epub 2019 May 14.

Dermatology Service, Irmandade da Santa Casa de Misericórdia de Porto Alegre, Porto Alegre, Brazil.

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http://dx.doi.org/10.1002/pbc.27810DOI Listing
August 2019
2 Reads

Signaling pathways and inhibitors of cells from patients with kaposiform lymphangiomatosis.

Pediatr Blood Cancer 2019 08 2;66(8):e27790. Epub 2019 May 2.

Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.

Background: Kaposiform lymphangiomatosis (KLA) is a rare lymphatic anomaly with significant morbidity and mortality. KLA is characterized by diffuse multifocal lesions comprised of focal areas of "kaposiform" spindled cells accompanying malformed lymphatic channels. The goal of this study was to identify activated signaling pathways in cells isolated from three KLA patients for the purpose of testing new therapies. Read More

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http://dx.doi.org/10.1002/pbc.27790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588438PMC
August 2019
6 Reads

Vascular Anomalies: Diagnosis of Complicated Anomalies and New Medical Treatment Options.

Hematol Oncol Clin North Am 2019 06;33(3):455-470

Division of Hematology, Hemangioma and Vascular Malformation Center, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Avenue, MLC 7015, Cincinnati, OH 45229, USA.

Vascular anomalies consist of a diverse group of disorders that are broadly categorized as tumors and malformations. . Recently, there has been significant genomic discovery allowing phenotype/genotype correlation of disease. Read More

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http://dx.doi.org/10.1016/j.hoc.2019.01.011DOI Listing
June 2019
3 Reads

Kasabach-Merritt syndrome arising from a vascular fistula.

Am J Emerg Med 2019 07 10;37(7):1394.e3-1394.e4. Epub 2019 Apr 10.

Internal Medicine, San Camillo Hospital, Rome, Italy.

A 58-year-old woman presented with gum bleeding, hematuria, and cutaneous ecchymoses. Left hip replacement had been performed five years prior. The overall findings of our work-up were consistent with ongoing DIC triggered by the presence of an arterio-venous left femoral fistula. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07356757193023
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http://dx.doi.org/10.1016/j.ajem.2019.04.013DOI Listing
July 2019
27 Reads

A report on Kaposiform hemangioendothelioma in the cervical spine.

Chin Med J (Engl) 2019 Jun;132(11):1378-1380

Department of Spine Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.

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http://dx.doi.org/10.1097/CM9.0000000000000217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629349PMC
June 2019
1 Read
1.016 Impact Factor

Liver Transplantation for Giant Hepatic Hemangioma: A Systematic Review.

Transplant Proc 2019 Mar 4;51(2):440-442. Epub 2019 Jan 4.

2nd Department of Propaedeutic Surgery, Laiko General Hospital, National and Kapodistrian University of Athens, Medical School, Athens, Greece.

Introduction: Despite their benign nature, liver hemangiomas (LH) are lesions that can cause major complications requiring intervention. Liver transplantation (LT) has been suggested as an effective treatment option in selected patients with giant LHs causing severe symptoms and cannot be treated otherwise. The aim of our study was to investigate the indications, aspects and post-operative outcomes of patients with a LH who underwent LT. Read More

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http://dx.doi.org/10.1016/j.transproceed.2019.01.018DOI Listing
March 2019
10 Reads

Successful treatment of an adult with Kasabach-Merritt syndrome using thalidomide, vincristine, and prednisone.

J Int Med Res 2019 Apr 26;47(4):1810-1814. Epub 2019 Feb 26.

2 Departments of Hematology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.

Objective: Kasabach-Merritt syndrome is a rare disease that mainly occurs in infants and adolescents. It usually manifests as disseminated intravascular coagulation and severe bleeding, and is associated with high mortality. However, its low incidence and clinical rarity in adults mean that there is currently no well-verified treatment regimen for this disease. Read More

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http://dx.doi.org/10.1177/0300060519830242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460612PMC
April 2019
15 Reads

[A case report of Kasabach-Merritt syndrome treated with vindesine sulfate].

Zhonghua Nei Ke Za Zhi 2019 Feb;58(2):143-145

Department of Hematology, Nanjing Drum Tower Hospital, Nanjing 210008, China.

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http://dx.doi.org/10.3760/cma.j.issn.0578-1426.2019.02.012DOI Listing
February 2019
11 Reads

[How do we treat Kaposiform Haemangioendothelioma?]

An Pediatr (Barc) 2019 Aug 25;91(2):122-124. Epub 2018 Oct 25.

Servicio de Neonatología, Hospital la Fe, Valencia, España.

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http://dx.doi.org/10.1016/j.anpedi.2018.09.002DOI Listing
August 2019
6 Reads

Nonimmune hydrops fetalis: identifying the underlying genetic etiology.

Genet Med 2019 06 9;21(6):1339-1344. Epub 2018 Nov 9.

Department of Obstetrics, Gynecology, & Reproductive Sciences, University of California, San Francisco, CA, USA.

Purpose: Numerous etiologies may lead to nonimmune hydrops fetalis (NIHF), and the underlying cause often remains unclear. We aimed to determine the proportion of NIHF cases in which the etiology was clearly determined in a large, contemporary, and diverse cohort, as well as to describe the etiologies with a focus on genetic causes.

Methods: Retrospective review of NIHF cases between 2015 and 2017 from the five University of California Fetal-Maternal Consortium sites. Read More

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http://dx.doi.org/10.1038/s41436-018-0352-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509016PMC
June 2019
39 Reads

Comparison of Corticosteroid and Vincristine in Treating Kaposiform Hemangioendothelioma and Tufted Angioma: A Systematic Review and Meta-Analysis.

Eur J Pediatr Surg 2019 Oct 29;29(5):401-407. Epub 2018 Oct 29.

Department of Pediatric Surgery, Children's Hospital of Fudan University, Shanghai, People's Republic of China.

Objective:  To evaluate the outcome and safety of corticosteroids and vincristine (VCR) in the treatment of kaposiform hemangioendothelioma (KHE) and tufted angioma (TA).

Materials And Methods:  Clinical studies involving corticosteroids and VCR therapies in treating KHE/TA were identified by using PubMed, Cochrane Library, OVID, EBSCO, CNKI, VIP, and Wanfang databases from their establishment date to December 2017. Randomized controlled trials, case-control, or case series with more than five cases were included. Read More

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http://dx.doi.org/10.1055/s-0038-1673708DOI Listing
October 2019
39 Reads

Kasabach-Merritt Syndrome in an Adult: A Comment

Turk J Haematol 2019 02 22;36(1):52-53. Epub 2018 Oct 22.

Retired Professor

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http://dx.doi.org/10.4274/tjh.galenos.2018.2018.0356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373517PMC
February 2019
12 Reads

Tufted angioma arising at the site of hepatitis B vaccination: A case report.

Turk J Pediatr 2018 ;60(2):188-190

Molecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Sepaskhah M, Hajizadeh J, Sari-Aslani F, Jowkar F. Tufted angioma arising at the site of hepatitis B vaccination: A case report. Turk J Pediatr 2018; 60: 188-190. Read More

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http://www.turkishjournalpediatrics.org/doi.php?doi=10.24953
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http://dx.doi.org/10.24953/turkjped.2018.02.011DOI Listing
May 2019
50 Reads

Kaposiform hemangioendothelioma without cutaneous involvement.

J Cancer Res Clin Oncol 2018 Dec 6;144(12):2475-2484. Epub 2018 Oct 6.

Department of Vascular and Interventional Radiology, Chengdu Women and Children's Central Hospital, Chengdu, 610031, China.

Purpose: We sought to characterize the clinical features and management of patients diagnosed as Kaposiform hemangioendothelioma (KHE) without cutaneous involvement.

Methods: The electronic patient chats at six Triple A hospitals in China were searched to find all patient diagnoses with KHE without cutaneous involvement.

Results: Of 30 patients (mean age at diagnosis, 55. Read More

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http://link.springer.com/10.1007/s00432-018-2759-5
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http://dx.doi.org/10.1007/s00432-018-2759-5DOI Listing
December 2018
48 Reads
3.080 Impact Factor

Proliferative Cells From Kaposiform Lymphangiomatosis Lesions Resemble Mesenchyme Stem Cell-like Pericytes Defective in Vessel Formation.

J Pediatr Hematol Oncol 2018 11;40(8):e495-e504

Department of Pediatric Surgery, Cincinnati Children's Hospital and Medical Center, Cincinnati, OH.

Kaposiform lymphangiomatosis (KLA) is a vascular anomaly featuring lymphatic expansion. It has no known cause, no effective treatment, and is associated with high morbidity. Proliferative cells from 3 KLA patient lesions were characterized relative to adiopose-derived mesenchyme stem cells (ADSCs) and cells derived from a patient with the related disease kaposiform hemangioendothelioma (KHE). Read More

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http://dx.doi.org/10.1097/MPH.0000000000001284DOI Listing
November 2018
40 Reads

Kaposiform haemangioendothelioma: new insights and old problems.

Authors:
R L Tower

Br J Dermatol 2018 08;179(2):253-254

Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, U.S.A.

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http://dx.doi.org/10.1111/bjd.16834DOI Listing
August 2018
6 Reads

Development of Kasabach-Merritt phenomenon following vaccination: More than a coincidence?

J Dermatol 2018 Oct 17;45(10):1203-1206. Epub 2018 Aug 17.

Division of Oncology, Department of Pediatric Surgery, West China Hospital of Sichuan University, Chengdu, China.

Kasabach-Merritt phenomenon (KMP) occurred uniquely in patients with kaposiform hemangioendothelioma (KHE) and tufted angioma (TA). We report the clinical characteristics of two patients with KHE involving the right upper arm. The patients demonstrated rapid enlargement of the lesion with severe KMP shortly after vaccination. Read More

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http://doi.wiley.com/10.1111/1346-8138.14598
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http://dx.doi.org/10.1111/1346-8138.14598DOI Listing
October 2018
55 Reads

Retrospective study on the outcomes of infantile tufted angioma complicated by Kasabach-Merritt Phenomenon.

Clin Chim Acta 2018 Nov 7;486:199-204. Epub 2018 Aug 7.

Department of Hemangioma and Vascular Malformation Surgery, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, 7 Weiwu Road, Zhengzhou 450003, China. Electronic address:

Objective: To analyze the clinical characteristics and treatment of pediatric tufted angiomas(TA)complicated by Kasabach-Merritt Phenomenon (KMP).

Method: A retrospective analysis was conducted on the clinical data and follow-up data of 13 patients diagnosed with TA complicated by KMP. Five male and 8 female patients with an average age of 5. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00098981183039
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http://dx.doi.org/10.1016/j.cca.2018.07.044DOI Listing
November 2018
38 Reads

Efficacy of sirolimus in an infant with Kasabach-Merritt phenomenon.

Pediatr Int 2018 Sep 8;60(9):887-889. Epub 2018 Aug 8.

Department of Pediatrics, Gifu University Graduate School of Medicine, Yanagido, Japan.

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http://dx.doi.org/10.1111/ped.13630DOI Listing
September 2018
13 Reads