13,528 results match your criteria Kardiologiia[Journal]


[A Case of Apical Hypertrophic Cardiomyopathy With Rare Anomaly of Coronary Arteries Origin].

Kardiologiia 2018 06;58(6):95-100

Treatment and Rehabilitation Center.

A clinical case of apical hypertrophic cardiomyopathy (HCM) in 44‑years old man is presented. In this patient exercise ECG testing and 24‑hour ECG monitoring revealed exercise-induced ST depression in the angiographically confirmed absence of coronary atherosclerosis. The uncommonness of this observation was the combination of HCM with a rare anomaly of coronary arteries origin. Read More

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June 2018
4 Reads

[Aneurysmal Degeneration of a Bioprosthesis].

Kardiologiia 2018 06;58(6):90-94

Federal State Budgetary Educational Institution of Higher Education, "Academician E. A. Vagner Perm State Medical Academy" of the Ministry of Health of the Russian Federation.

We present a clinical case of successful correction of aneurismatic dilatation of the anastomosis zone after allotransplant implantation. In 2004 this patient underwent implantation of an arterial allotransplant of "complex architectonics" because of trauma of the iliofemoral arterial segment. After 12 years he reported appearance of discomfort in the left side of the abdomen. Read More

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June 2018
4 Reads

[Chronic Heart Failure With Preserved Ejection Fraction: Effective Treatment Possible?]

Kardiologiia 2018 06;58(6):85-89

Federal State Budgetary Educational Institution of Higher Education "Kuban State Medical University" of the Ministry of Health of the Russian Federation.

Chronic heart failure with preserved ejection fraction (HFpEF) accounts for about 50% of cases of heart failure, but pharmacotherapy that improves its outcomes has not been developed. The proven principle of improving outcomes in patients with chronic heart failure with a reduced of left ventricular ejection fraction is the decrease in heart rate. The article discusses situations in which treatment with β-blockers is not effective or negatively affects outcomes. Read More

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June 2018
7 Reads

[Heart Failure in Patients With Preserved Ejection Fraction - Pumping Heart Failure?]

Kardiologiia 2018 06;58(6):79-84

Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences.

The review analyzes literature data on the phenomenon of chronic heart failure as a clinical syndrome of hypoperfusion of organs and systems of the body due to multiple causes of pumping inadequacy of the circulatory system. Special attention is paid to diastolic heart failure of different origin. Attention is drawn to the fact that integrated quantitative characteristic of CHF of any origin is indexed cardiac output (CO) rather than ejection fraction, and that allocation of systolic and diastolic CHF is a relatively conventional division concept. Read More

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June 2018
2 Reads

[The Role of Lipoprotein(a) in the Development of Peripheral and Carotid Atherosclerosis].

Kardiologiia 2018 06;58(6):70-78

National Medical Research Center for Cardiology.

Lipoprotein(a) [Lp(a)] consists of an LDL-like particle in which the apolipoprotein B100 is covalently bound to apolipoprotein(a) by a single disulfide bond. Lp(a) is synthesized in the liver and its plasma concentration varies from 0 to 400 mg/dl. Increased level of Lp(a) is considered to be an independent risk factor of cardiovascular diseases and coronary heart disease. Read More

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June 2018
5 Reads

[Current State and Future Technologies of Nuclear Imaging in Cardiology].

Kardiologiia 2018 06;58(6):61-69

Russian Cardiology Research and Production Complex.

In this review, modern possibilities of nuclear imaging modalities in cardiology are considered. Perspectives of this branch of radiology are described according to the latest technological and methodological inventions and new clinical data. Read More

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June 2018
1 Read

[Early Markers of Cardiovascular Risk in Women With Hereditary Burdening by Cardiovascular Diseases].

Kardiologiia 2018 06;58(6):51-60

Federal State Budgetary Educational Institution of Higher Education, "A. I. Evdokimov Moscow State University for Medicine and Dentistry" of the Ministry of Health of the Russian Federation.

Purpose: to identify early markers of development of cardiovascular diseases (CVD) in women.

Materials And Methods: Female firstdegree relatives from 39 families formed 2 groups: families (n=19) containing mothers with arterial hypertension (AH) (group 1) and healthy daughters (group 1a); families (n=20) containing practically heathy mothers (group 2) and healthy daughters (group 2a). We assessed data of anamnesis, including registration of cardiovascular risk factors, and family history of CVD. Read More

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June 2018
4 Reads

[Angiographic Results After Coronary Artery Bypass Grafting].

Kardiologiia 2018 06;58(6):44-50

Federal Сenters of High Medical Technologies Health Ministry.

The main place among cardiovascular diseases takes coronary heart disease. The number of coronary artery bypass surgery increases every year. The large number of coronary artery bypass grafting (CABG) performed worldwide. Read More

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[Types of Conduction Disturbances in Pulmonary Veins].

Kardiologiia 2018 06;58(6):37-43

Institute of Cardiology of Russian Cardiology Scientific and Production Complex.

Recently, the notion that in 60-80 % of cases the origin of the pulmonary veins (PV) is the place of origin of atrial fibrillation (AF) has become widespread. It has been shown that in this area, under the action of norepinephrine (HA), in the absence of stimulation, an intrinsic rhythm appears. Using two-channel microelectrode leads (from the mouth and distal part of the PV) in rats weighing 350-450 grams, it was found that: 1) in the distal part of PV there are cells with depolarized resting potential (RP) up to -50 mV, which under normal conditions are not excitable; 2) in 17 experiments out of 23, various blocks of excitation conduction along PV were revealed; 3) in 8 experiments out of 23, a reflected excitation wave - echo from PV - was recorded. Read More

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[Common Carotid Intima-Media Thickness, Levels of Total and High-Molecular Weight Adiponectin in Women With Abdominal Obesity].

Kardiologiia 2018 06;58(6):29-36

Federal State Budgetary Institution "Federal Almazov North-West Medical Research Center" of the Ministry of Health of the Russian Federation.

Objective: to investigate influence of different forms of adiponectin on carotid intima-media thickness (CIMT) in women with abdominal obesity (AO) in St.‑Petersburg. It has been recognized before that AO is associated with cardiovascular diseases, including atherosclerosis, but mechanism of this association remains unclear. Read More

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June 2018
9 Reads

[Characteristics of Disturbances of Heart Rhythm and Conduction Among Patients Attending Consultation of a Cardiologist at Ambulatory Stage].

Authors:
S I Getman

Kardiologiia 2018 06;58(6):20-28

Medical Center Primorsky District.

We included in this study 652 patients with persistent disturbances of heart rhythm and conductiion who attended a cardiologist of the consulting center during 2 years. Analysis of results of examination of these patients was aimed at identification of possible etiologic factors of the appearance of arrhythmias. In 48 patients (8. Read More

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June 2018
1 Read

[Structural and Functional Characteristics of the Heart in Patients With "Constrictive", "Pseudo-Normal" and "Restrictive" Types of the Left Ventricular Diastolic Dysfunction].

Kardiologiia 2018 06;58(6):13-19

Regional State Budgetary Institution of Health Care "Saint Ioasaph Belgorod Regional Clinical Hospital".

Purpose: to study structural functional characteristics of the heart in patients with various types of abnormalities of diastolic function (DF) based on data obtained at stress echocardiography (stress EchoCG) and echocardiographic indexes of myocardial deformation.

Materials And Methods: We included in this study 110 patients with hypertensive disease (HD), clinically manifest chronic heart failure (CHF), and abnormal DF of the left ventricle (LV) in the absence of coronary artery stenosis. All patients underwent standard clinical and laboratory examination, EchoCG with measurement of 3‑dimensional global longitudinal strain (GLS), and stress EchoCG on treadmill with evaluation of DF parameters. Read More

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June 2018
6 Reads

[ADP-Induced Recalcified Blood Clotting Time as a Marker of Rethrombosis Risk and Effectiveness of Antiplatelet Therapy in Acute Coronary Syndrome].

Kardiologiia 2018 06;58(6):5-12

State Budgetary Educational Institution of Higher Professional Education, "V. I. Razumovsky Saratov State Medical University" of the RF Ministry of Health Care.

Purpose: to assess the possibility of the use of ADP induced blood-clotting time measurement in clinical practice prognostication of the course of acute coronary syndrome (ACS) and assessment of effectiveness of antiplatelet therapy (APT).

Materials And Methods: We enrolled in the study 163 male patients admitted to the coronary unit for acute coronary syndrome (ACS) and 38 male practically healthy volunteers (PHV). ADP induced blood-clotting time (ADP BCT) was measured as time (sec) between addition of ADP (10 μcmol) to recalcificated sample of citrate blood and clot formation. Read More

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June 2018
8 Reads

[Significance of adipose tissue mass for the clinical course of pneumonia associated with decompensated CHF].

Kardiologiia 2018 SOct(S10):61-68

Federal State Budgetary Educational Institution of Higher Education, "Pirogov Russian National Research Medical University" of the Ministry of Health of the Russian Federation.

Background: Pneumonia is one of most important causes of in-hospital mortality in patients with decompensated chronic heart failure (CHF).

Aim: To evaluate the effect of adipose tissue mass and body weight index (BWI) on prognosis for patients with communityacquired pneumonia and decompensated CHF.

Materials And Methods: The study included 286 patients aged 53-90 with BWI 18. Read More

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October 2018
4 Reads

[Significance of comorbidity for patients with chronic lymphocytic leukemia].

Kardiologiia 2018 SOct(S10):51-60

S. P. Botkin Municipal Clinical Hospital ministry of the Moscow Healthcare Department.

Background: Chronic lymphocytic leukemia (CLL) remains an uncurable disease, in which the age, number and severity of comorbidities primarily determine the choice of therapeutic tactics and objectives.

Aim: To evaluate actual comorbidity and polymorbidity in patients with CLL and a possible relationship between the diseases and comorbidities that are considered concurrent and side effects of the administered treatment.

Materials And Methods: The study consisted of two parts. Read More

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October 2018
2 Reads

[Neutrophil gelatinase-associated lipocalin for early diagnosis of acute kidney injury in patients with acute decompensated heart failure].

Kardiologiia 2018 SOct(S10):44-50

National Medical Research Center for Cardiology.

Background: the incidence of acute kidney injury (AKI) is high in patients with acute decompensated heart failure (ADHF) and is linked with increased morbidity and mortality rates. Predictive biomarkers of AKI could allow improve outcomes in AKI.

Purpose: to evaluate the value of serum neutrophil gelatinase-associated lipocalin (NGAL) concentrations for early diagnosis of AKI in patients with ADHF with left ventricular (LV) systolic function. Read More

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October 2018
4 Reads

[Role of ST2 biomarker for the evaluation of myocardial remodeling in patients with ischemic heart failure with preserved ejection fraction].

Kardiologiia 2018 SOct(S10):33-43

Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences.

Aim: 1) To study the role of soluble ST2 (sST2) in evaluation of left ventricular (LV) myocardial remodeling and 2) to evaluate the predictive value of sST2 for development of adverse cardiovascular events (CVE) during 12 months following myocardial revascularization in patients with ischemic heart disease (IHD) and chronic heart failure (CHF) with preserved LV ejection fraction (EF).

Materials And Methods: The study included 55 patients (42 men) with IHD and NYHA FC I-III CHF with LV EF 63 [59; 65] % aged 65 [58; 69] who were scheduled for myocardial revascularization. Echocardiographic evaluation of myocardial stress and myocardial remodeling indexes was performed for all patients. Read More

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October 2018
3 Reads

[Prognostic value of liver stiffness in decompensated heart failure: results of prospective observational transient elastography-based study].

Kardiologiia 2018 SOct(S10):20-32

Duke University and Duke Clinical Research Institute.

Objective: There is growing evidence that liver stiffness (LS) in decompensated heart failure (DHF) is related to congestion, however data about its impact on outcomes are limited. The aim of the study was to evaluate associations and long-term prognostic significance of LS measured by transient elastography (TE) in DHF.

Methods: Single-center prospective observational study of 194 patients hospitalized with DHF, of whom 71 % were male, 68 ± 11 years (mean ± SD), had a left ventricular ejection fraction of 39±14%. Read More

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October 2018
4 Reads

[Results of 3 years work of the Russian hospital register of chronic heart failure (RUssian hoSpital Heart Failure Registry - RUS-HFR): relationship between management and outcomes in patients with chronic heart failure].

Kardiologiia 2018 SOct(S10):9-19

Federal State Budgetary Institution "Federal Almazov North-West Medical Research Center" of the Ministry of Health of the Russian Federation.

Aim: To analyze management and outcomes in patients with CHF managed by specialists in heart failure (HF) or general cardiologists/physicians in real-life clinical practice.

Materials And Methods: Survival rate, rehospitalization rate, general health condition, and the administered therapy were evaluated for HF patients with reduced LV ejection fraction at three years of discharge from cardiological hospitals. These patients had been included in a prospective, multicenter, observational study, "The Russian Hospital HF Registry" (RUS-HFR). Read More

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October 2018
4 Reads

[Analysis of the interrelation between immune factors and inflammatory markers, and the course of chronic heart failiure in patients with rheumathoid arthritis].

Kardiologiia 2018 SOct(S10):4-8

State Budgetary Educational Institution of Higher Professional Education, "Irkutsk State Medical University" at the RF Ministry of Health Care.

This review presents relevant information about development and course of chronic heart failure (CHF) associated with rheumatoid arthritis (RA). One of the most discussed issues is the effect of systemic inflammatory process on prognosis of CHF. The review focused on current evidence for significance of this comorbidity in CHF. Read More

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October 2018
6 Reads

[Clinical Case of Successful Nephrectomy and Stenting of the Coronary Arteries in Acute Period of Myocardial Infarction in a Patient With Kidney Cancer].

Kardiologiia 2018 Oct(10):96-100

Federal State Budgetary Educational Institution of Higher Education, "Pirogov Russian National Research Medical University" of the Ministry of Health of the Russian Federation.

We describe in this case report the clinical situation of development of massive macrohematuria at the background of dual antiplatelet therapy in a patient in the acute period of myocardial infarction with an established diagnosis of kidney cancer and a burdened cardiac anamnesis. Despite the high anesthetic and operational risk of complications, due to the need for coronary angiography with possible stenting of the coronary arteries, left ventricular thrombus and the impossibility of canceling antiplatelet agents and anticoagulants, the patient underwent radical nephrureterectomy, which allowed further stenting of the anterior interventricular artery occlusion and thus to reduce the risk of developing a repeated myocardial infarction. Read More

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October 2018
7 Reads

[Novel Possibilities in Pharmacotherapy of Patients With Chronic Heart Failure].

Kardiologiia 2018 Oct(10):88-95

I.M. Sechenov First Moscow State Medical University (Sechenov University).

In this article we have described clinical pharmacology and data of clinical studies of an innovational drug valsartan + sacubitril in patients with chronic heart failure (CHF). The use of supramolecular complex valsartan + sacubitril allows to elevate quality of life and improve prognosis of patients with CHF. High efficacy of valsartan+sacubitril relative to impact on composite primary end-point (cardiovascular death + hospitalization due to CHF) was demonstrated in the clinical trial PARADIGM-HF in which it was compared with angiotensin converting enzyme inhibitor enalapril. Read More

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October 2018

[Impact of Glycemic Variability on Cardiovascular Risk in Diabetes].

Authors:
V V Klimontov

Kardiologiia 2018 Oct(10):80-87

Scientific Institute of Clinical and Experimental Lymphology.

A growing body of evidences indicates the role of increased glucose variability (GV) as an independent cardiovascular risk factor in diabetes. It has been shown that high GV is associated with coronary and carotid atherosclerosis in diabetic subjects. The impact of enhanced glycemic fluctuations on vascular wall is mediated through non-enzymatic glycation, oxidative stress, activation of inflammatory pathways, and endothelial dysfunction. Read More

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October 2018
10 Reads

[Cognitive Disorders and Dementia in Old Patients With Arterial Hypertension].

Kardiologiia 2018 Oct(10):71-79

Central State Medical Academy, President Management Department RF.

The article describes the definition of dementia, its diagnostic criteria, classification. Differences in the pathogenesis and clinical manifestations of different types of dementia are considered. The issues of interrelation of arterial hypertension and the risk of development of cognitive disorders and dementia in old and very old people are discussed in detail. Read More

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October 2018
4 Reads

[Ischemic Heart Disease in Subjects of Young Age: Current State of the Problem: Prevalence and Cardio-Vascular Risk Factors].

Kardiologiia 2018 Oct(10):53-58

National Medical Research Center for Cardiology.

Ischemic heart disease (IHD) occurring at age less than 55 in men and less than 65 years in women is designated as premature IHD. However, in different studies these age limits vary from 35 years to 65 years. Among the population of working age in the Russian Federation mortality from IHD is several times higher than in the US and Europe. Read More

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October 2018
2 Reads

[Anticoagulant Therapy in Elderly Patients With Atrial Fibrillation].

Kardiologiia 2018 Oct(10):45-52

I.M. Sechenov First Moscow State Medical University (Sechenov University).

Is this paper discuss problems of selection of anticoagulant therapy in elderly patients with atrial fibrillation, use of unreasonably low doses of anticoagulants, their risks and adherence to therapy is discussed in the paper. Read More

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October 2018

[Preventive Counselling With the Use of Remote Technologies Provides Effective Control of Metabolic Risk Factors in Patients With High and Very High Cardiovascular Risk].

Kardiologiia 2018 Oct(10):34-44

Federal State Institution National Research Center for Preventive Medicine.

Purpose: to assess the impact of preventive counseling with focus on diet modification on lipid and metabolic parameters in patients with high / very high cardiovascular (CV) risk who visited Health centers.

Materials And Methods: This was a prospective randomized controlled study of patients aged 40 to 65 years with high/very high CV risk (≥5% according to the Systematic Coronary Risk Evaluation scale [SCORE]) and any 2 criteria for metabolic syndrome. Patients were 1:1 randomized into 2 groups. Read More

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October 2018
4 Reads

[Prediction of Risk of Calcification of Heart Valve Bioprostheses on the Basis of Comprehensive Assessment of Recipients Clinical Factors and Their Compliance With Therapy].

Kardiologiia 2018 Oct(10):27-33

Research Institute for Complex Issues of Cardiovascular Diseases.

Purpose: The development of the prediction methods of calcification risk of heart valve bioprostheses (BP) based on comprehensive assessment of the impact of clinical factors of the recipients and their adherence to medication.

Materials And Methods: We performed a retrospective study of clinical status and adherence to drug therapy of 170 recipients of heart valve BP with (n=63) and without (n=109) calcification. We used the method of comprehensive assessment of the analyzed parameters with estimation of prognostic coefficients for each of them, followed by calculation of integral indicators and construction on their basis of prognostic models for the various intervals of BP functioning. Read More

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October 2018
5 Reads

[Analysis of Relationship Between Parameters of Arterial Stiffness and Lipid Profile in Patients With Metabolic Syndrome].

Kardiologiia 2018 Oct(10):19-26

Scientific and Research Institute of Cardiology and Internal Diseases, Almaty.

Aim: to elucidate relationships between parameters of arterial stiffness (carotid-femoral pulse wave velocity [cfPWV] and cardio-ankle vascular index [CAVI]) and standard lipid profile parameters in patients with metabolic syndrome (MS).

Materials: We included in this study 100 subjects (45 men, 55 women) aged 40-70 (mean 56.54±8. Read More

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October 2018
2 Reads

[Changes of Content of Matrix Metalloproteinases and Their Tissue Expression in Various Types of Atherosclerotic Plaques].

Kardiologiia 2018 Oct(10):12-18

National Medical Research Center named after acad. E. N. Meshalkina.

Aim: to investigate diagnostically significant for atherosclerotic plaques (ASP) of various types parameters of activity of matrix metalloproteinases (MMP-3, MMP-7, MMP-9) in homogenates, as well as tissue expression of MMP-2, MMP-9 and collagen type IV.

Materials And Methods: We included in this study 54 men with coronary atherosclerosis without acute coronary syndrome who underwent coronary artery bypass surgery with endarterectomy. In the obtained samples we determined levels of MMP-3, MMP-7, and MMP-9 (by enzyme immunoassay), as well as tissue expression of antibodies to MMP-2, MMP-9 and collagen type IV. Read More

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October 2018
1 Read

[Arterial Hypertension and Methylenetetrahydrofolate Reductase C677T Gene Polymorphism].

Kardiologiia 2018 Oct(10):5-11

Republican Science and Practice Center "Cardiology ".

Objective: to determine the association of polymorphisms of C677T methylenetetrahydrofolate reductase (MTHFR) gene with essential arterial hypertension (EH) in the group of patients of Belarusian ethnicity.

Methods: The clinical examination and molecular genetic study of the polymorphism C677T of MTHFR gene by polymerase chain reaction and restriction fragment length polymorphism analysis were performed in 423 people, including 315 patients with EH and 108 healthy individuals.

Results: The distribution of C and T alleles of polymorphism C677T of the MTHFR gene in hypertensive patients was 67. Read More

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October 2018
3 Reads

[Falling risk factors in patients with arterial hypertension 55+ years old].

Kardiologiia 2018 SSep(S9):58-64

Regional State Budgetary Institution of Health Care "Saint Ioasaph Belgorod Regional Clinical Hospital".

Arterial hypertension (AH) is the most prevalent cardiac risk factor in old patients. Falls-related complications includes increased disability and mortality, decreased activity levels, quality of life, and overall health status. So falls are an important health problem. Read More

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October 2018
6 Reads

[Clinical and demographic features of patients with stroke and atrial fibrillation].

Kardiologiia 2018 SSep(S9):48-57

Republican State Enterprise, "S. D. Asfendiyarov Kazan National Medical University".

Background: Stroke takes the second place among all causes for cardiovascular death and the first place in mortality and disability among other nervous system diseases. Atrial fibrillation (AF) is presently is a commonly recognized, independent risk factor for ischemic stroke, which fivefold increases the risk of an unfavorable outcome. Prevention of stroke is a complicated medical and social challenge. Read More

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October 2018

[Prognostic markers for the development of adverse outcomes in patients with chronic obstructive pulmonary disease and chronic heart failure].

Kardiologiia 2018 SSep(S9):39-47

State Budgetary Educational Institution of Higher Professional Education, "V. I. Razumovsky Saratov State Medical University" of the RF Ministry of Health Care.

Aim: To identify markers of adverse outcomes in patients with a combination of chronic obstructive pulmonary disease (COPD) and chronic heart failure (CHF).

Materials And Methods: 35 patients with COPD (without an anamnesis of coronary heart disease), 68 patients with COPD and CHF, 28 patients with CHF of ischemic genesis who were on treatment at the State Regional Clinical Hospital of Saratov were examined. The levels of the N-terminal fragment of the natriuretic peptide, galectin-3, the highly sensitive C-reactive protein, the proteins that bind fatty acids, the stiffness parameters of the arterial wall were determined; echocardiography was performed, calculated the index of comorbidity of Charlson. Read More

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October 2018
2 Reads

[Comorbidity and polymorbidity - a modern interpretation and urgent tasks facing the therapeutic community].

Authors:
E I Tarlovskaya

Kardiologiia 2018 SSep(S9):29-38

Privolzhsky Research Medical University.

The article presents an overview of data on polymorbidity. It is shown that polymorbidity is associated with higher mortality, disability, side effects of treatment, increased use of health system resources, and also with a lower quality of life. The issues of effective treatment of people with multiple chronic diseases are discussed. Read More

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October 2018
1 Read

[Thrombosis in patients with malignancy].

Kardiologiia 2018 SSep(S9):19-28

Federal Research Clinical Center for specialized types of health care and medicaltechnologies of Federal Biomedical Agency of Russia.

Thrombosis traditionally considered as a complication of cardiovascular disease, however, this problem until recently was rarely taken into account in the presence of cancer. Although the association between cancer and thrombosis has been known almost 150 years ago, awareness of the impact of thrombotic complications have increased only now. Cancer is an independent major risk factor for venous thromboembolism (VTE), which is the leading cause of death of cancer patient. Read More

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October 2018
1 Read

[Physical activity and physical training as method of prevention of cardiovascular diseases].

Kardiologiia 2018 SSep(S9):10-18

Federal State Budgetary Scientific Institution «Central Tuberculosis Research Institute».

A growing body of data demonstrates that exercise capacity is a potentially stronger predictor of mortality than established risk factors such as smoking, hypertension, obesity, high cholesterol, and type 2 diabetes mellitus. Individuals who maintain a regular program of PA that is longer in duration, of greater intensity, or both are likely to derive greater benefit than those who engage in lesser amounts. In this review, the authors have shown the possibility of assessing physical activity and the main provisions of the appointment of physical training to improve and preserve the cardiorespiratory fitness. Read More

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October 2018
5 Reads

[Vascular Complications Of Cancer Chemotherapy].

Kardiologiia 2018 SSep(S9):4-9

I.M. Sechenov First Moscow State Medical University (Sechenov University).

Development and use of new anticancer drugs has resulted in the improving of 5‑year survival rates in patients with cancer. However, many of the modern chemotherapies are associated with cardiovascular toxicities that increases cardiovascular risk in cancer patients, including hypertension, heart failure, thrombosis and thromboembolism, cardiomyopathy, and arrhythmias. These side effects limitation restrict treatment options and farther perspectives. Read More

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October 2018
3 Reads

[Double Blockade of Aldosterone Receptors as a Method of Elimination Negative Effects of Non-Steroidal Anti-Inflammatory Drugs in Chronic Heart Failure].

Kardiologiia 2018 Sep(9):96-100

Federal State Budgetary Educational Institution of Higher Education "Rostov State Medical University" of the Ministry of Health of the Russian Federation.

The article deals with the dynamics of echocardioscopy indices during 1.5 years in a patient who underwent an acute myocardial infarction (MI). Two months after the MI left ventricular (LV) end-diastolic size and LV volume were 61 mm and 190 ml, respectively; LV ejection fraction (EF) was 42%. Read More

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September 2018
2 Reads

[The Problem of Adherence to Therapy in Cardiology].

Kardiologiia 2018 Sep(9):89-95

National Medical Research Center named after acad. E. N. Meshalkina.

This review article presents results of studies on adherence to drug therapy of patients after discharge from hospital. It contains analysis of the reasons for poor adherence, assessment of the impact of quality of adherence on the immediate and long-term results of surgical and medical treatment, structured methods of improvement of adherence to therapy; as well as economic aspects of the problem. Read More

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September 2018
7 Reads

[Atrial fibrillation as Risk Factor for Development of Cognitive Function Impairment and Dementia. Potential of Anticoagulant Therapy in Their Prevention].

Kardiologiia 2018 Sep(9):76-88

Medical Academy of Continuing Education.

This article presents an overview of data of Russian and foreign literature on possible associations between cognitive impairment and atrial fibrillation (AF). It includes modern classification of cognitive impairment, mechanisms of the effect of AF on cognitive functions and development of dementia, recommendations for the prevention of cognitive impairment in patients with AF. Special attention is paid to the assessment of cognitive status, and safe anticoagulant therapy, which is a priority in the prevention of cognitive impairment in patients with AF. Read More

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September 2018
6 Reads

[Annual Scientific Session of American College of Cardiology 2018: Results of Clinical Studies].

Kardiologiia 2018 Sep(9):67-74

Federal State Institution National Research Center for Preventive Medicine.

The article contains report of 15 most important clinical studies presented at 67‑th Annual Scientific Session of American College of Cardiology (Orlando, USA, March 10-12, 2018). Read More

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September 2018
1 Read

[Position Statement on Challenges in Assessing Cause-Specific Mortality].

Kardiologiia 2018 Sep(9):63-66

National Medical Research Center for Cardiology.

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September 2018
1 Read

[Metabolomic Profiling of Patients With Cardiovascular Diseases].

Kardiologiia 2018 Sep(9):59-62

I.M. Sechenov First Moscow State Medical University (Sechenov University).

Cardiovascular diseases (CVD) are the main cause of death worldwide. A broad study of the pathogenetic mechanisms of the CVD onset and progression has led to understanding of the importance of endothelial dysfunction (ED) in these processes. During recent years intensive work has been conducted in the direction of searching for markers of ED. Read More

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September 2018
4 Reads

[Clinical-Epidemiological Program of Studying Psychosocial Risk Factors in Cardiological Practice in Patients With Arterial Hypertension and Ischemic Heart Disease: First Results of a Multicenter Study in Russia].

Kardiologiia 2018 Sep(9):47-58

Federal State Institution National Research Center for Preventive Medicine.

Background: More than 10 years passed since conduction of the first clinical-epidemiological study of prevalence of psychosocial risk factors (PSRF) in patients with arterial hypertension (AH) an/or ischemic heart disease in Russian Federation.

Purpose: to assess current prevalence of PSRF in patients with AH/CHD and their relationship with traditional risk factors.

Materials And Methods: Patients with verified AH and/or CHD aged ≥55 years were included into this cross-sectional study in 30 cities of Russia representing 7 federal districts according to the following procedure. Read More

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September 2018
7 Reads

[Left Ventricular Myocardial Hypertrophy as a Result of Arterial Hypertension Among Mountain Shoria Population. The Role of Genetic Polymorphism].

Kardiologiia 2018 Sep(9):37-46

Research Institute for Complex Issues of Cardiovascular Diseases.

Objective: to establish associations of candidate genes ACE, AGT, AGTR1, ADRB1, ADRA2B, MTHFR and NOS3 polymorphisms with left ventricular myocardial hypertrophy (LVH) in patients with arterial hypertension (AH) among the indigenous (the Shors) and non-indigenous population of Mountain Shoria.

Materials And Methods: We examined 788 people in a clinical and epidemiological study of compactly living population in the remote areas of Mountain Shoria, located in the south of Western Siberia (468 members of indigenous ethnic group [the Shors], 320 members of non-indigenous ethnic group [90% Caucasian]). Diagnosis of AH was set in accordance with recommendations of Society of Cardiology of the Russian Federation/Medical Society of the Russian Federation on the Problem of Arterial Hypertension (RMOAG) (2010). Read More

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September 2018
3 Reads

[Dynamics of Quality of Life in Patients With Aortic Stenosis After Aortic Valve Replacement With a Biological or Mechanical Prosthesis].

Kardiologiia 2018 Sep(9):31-36

Federal Center for Cardiovascular Surgery.

Objective: To assess dynamics of the quality of life (QOL) in patients of the older age group of with initial aortic stenosis in 1, 3, and 5 years after replacement of the aortic valve (AV) with biological or mechanical prosthesis.

Materials And Methods: QOL was assessed in 282 patients who underwent aortic valve replacement with a biological or mechanical prosthesis. Criterion for inclusion in this retrospective single-center study was primary and elective nature of the operation. Read More

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September 2018
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[Combined Therapy of Arterial Hypertension With Triple Fixed-Dose Combination of Amlodipine/Indapamide/Perindopril Arginine in Real Clinical Practice: the Organization and the Main Results of the DOKAZATEL'STVO (Proof) Study].

Kardiologiia 2018 Sep(9):21-30

Federal State Autonomous Educational Institution of Higher Education, "Peoples' Friendship University of Russia".

Aim: to assess antihypertensive efficacy of the fixed-dose amlodipine/indapamide/perindopril arginine combination in hypertensive patients in real clinical setting.

Methods: We included in the 3‑month clinical program 1 599 patients with arterial hypertension (AH) (38.8 % men, mean age 61. Read More

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September 2018
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[Predictors of Obstructive Sleep Apnea Syndrome According to Results of Clinical Examintion and Ambulatory Blood Pressure Monitoring].

Kardiologiia 2018 Sep(9):12-20

Russian Interior Ministry hospital in Voronezh region.

Objective: to determine the predictors of obstructive sleep apnea syndrome (OSAS) basing on clinical examination, results of night pulse oximetry, daily dynamics of heart rate and blood pressure (BP) in men with newly diagnosed arterial hypertension (AH).

Materials And Methods: Men (n=197, mean age 40.1 ± 8. Read More

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September 2018
2 Reads

[Impact of Arterial Hypertension on the Formation of the Risk of Mortality. Results of a 27‑Year Prospective Study].

Kardiologiia 2018 Sep(9):5-11

Siberian State Medical University of the RF Ministry of Health Care.

Objective: to investigate the impact of arterial hypertension (AH) on formation of the risk of total and cardiovascular mortality.

Materials And Methods: The 27‑year cohort prospective study was conducted on the sample of unorganised population of Tomsk (n=1 546, age 20-59 years, 630 men, 916 women). At the first stage (1988-1991) we studied the prevalence of AH, at the second stage (2015) we investigated overall and cardiovascular mortality and the prognostic significance of AH in shaping mortality. Read More

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September 2018
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