13,769 results match your criteria Journal of the neurological sciences[Journal]


Flat panel imaging of occlusion site and collateral scores for emergent large vessel occlusion.

J Neurol Sci 2019 Apr 10;401:12-16. Epub 2019 Apr 10.

Siemens Medical Solutions, Hoffman Estates, IL, USA.

Introduction: Flat panel imaging for emergent large vessel occlusion can be acquired prior to mechanical thrombectomy (MT). In this study, we examined patients undergoing MT with computed tomography angiography (CTA) to determine agreement on the site of occlusion and CTA collateral score (CS).

Methods: Flat Panel CTA (FP-CTA) was acquired before MT. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S0022510X193017
Publisher Site
http://dx.doi.org/10.1016/j.jns.2019.04.013DOI Listing
April 2019
1 Read

The Sub-Saharan Africa Conference on Stroke (SSACS): An idea whose time has come.

J Neurol Sci 2019 Mar 29;400:194-198. Epub 2019 Mar 29.

Department of Neurology, University of California, San Francisco, USA.

Stroke is a leading cause of global morbidity and mortality. Sub-Saharan Africa (SSA), where an unprecedented rise in stroke burden is currently raging, has the highest age-standardized stroke incidence, stroke prevalence, and stroke mortality rates. This is in sharp contrast to the relative decline in stroke incidence in high-income countries over the past four decades through better awareness and control of vascular risk factors. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.03.026DOI Listing

Incidence, characteristics and outcomes in patients with embolic stroke of undetermined source: A population-based study.

J Neurol Sci 2019 Apr 6;401:5-11. Epub 2019 Apr 6.

Department of Neurology, University Hospital of Alexandroupolis, Democritus University of Thrace, School of Medicine, Alexandroupolis, Greece.

Embolic stroke of undetermined source (ESUS) represents a subgroup of cryptogenic ischemic stroke (CS) distinguished by high probability of an underlying embolic mechanism. There are scarce population-based data regarding the incidence, characteristics and outcomes of ESUS. Consecutive patients included with first-ever ischemic stroke of undetermined cause in the previously published population-based Evros Stroke Registry were further subdivided into ESUS and non-ESUS CS. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.04.008DOI Listing

Can we stop the stuttering in stroke? Interventions in 40 patients with acute lacunes.

J Neurol Sci 2019 Apr 6;401:1-4. Epub 2019 Apr 6.

Department of Neurology, Division of Critical Care Neurology, Mayo Clinic, Rochester, MN, United States of America.

Background: Whether any treatment can stop fluctuations of stuttering lacunar syndromes (SLS) is unclear. Case reports have variably suggested effectiveness of intravenous thrombolysis, dual antiplatelet treatment, blood pressure augmentation and anticoagulation. We aim to describe our experience with different treatments used in in patients presenting with SLS and their effect on clinical fluctuations and functional outcome. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S0022510X193016
Publisher Site
http://dx.doi.org/10.1016/j.jns.2019.04.009DOI Listing
April 2019
1 Read

Increased free prostate specific antigen serum levels in Alzheimer's disease, correlation with Cognitive Decline.

J Neurol Sci 2019 Apr 5;400:188-193. Epub 2019 Apr 5.

Department of Neurology, Stroke Center, Buffalo Medical Center, Buffalo, NY, USA.

Background/aims: Prostate specific antigen (PSA) is regulated by steroid hormones, such as testosterone, the serum levels of which are altered in patients with Alzheimer's disease (AD).This pilot study compared serum levels of the free (f) PSA between AD, mild cognitive impairment (MCI), and control subjects, and evaluated the relationship between fPSA serum levels and cognitive assessment tests and neuroimaging data. In addition, in a subgroup of AD patients, we correlated fPSA serum levels with the existing data on serum levels of amyloid-beta (Aβ), and iron-related proteins, including hepcidin and ferritin. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.04.006DOI Listing

Acute truncal ataxia in a healthy adult with varicella zoster virus cerebellitis: A case report and literature review.

J Neurol Sci 2019 Apr 2;400:186-187. Epub 2019 Apr 2.

Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA.

Acute cerebellitis is a well recognized complication of varicella zoster virus (VZV) infection in children. It has been described in adults in the setting of virus reactivation with a preceding herpes zoster rash, but it is exceedingly rare in adults who are not elderly or immunocompromised, particularly in the absence of a rash. To our knowledge, there has been only one reported case of acute cerebellitis in an immunocompetent adult less than age 65 with virological confirmation of acute VZV infection. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.04.001DOI Listing

The features of the m.10197G>A mtDNA mutation.

J Neurol Sci 2019 Apr 4;400:184-185. Epub 2019 Apr 4.

IRCCS Fondazione Stella Maris, viale del Tirreno 331, 56128 Calambrone, Pisa, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.04.005DOI Listing
April 2019
5 Reads

Diagnostic and therapeutic aspects of Leigh syndrome due to the variant m.10197G>A.

Authors:
Josef Finsterer

J Neurol Sci 2019 Apr 3;400:182-183. Epub 2019 Apr 3.

Krankenanstalt Rudolfstiftung, Vienna, Austria. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.04.004DOI Listing

Differential diagnosis of apogeotropic positional nystagmus in the emergency room.

J Neurol Sci 2019 Apr 2;400:180-181. Epub 2019 Apr 2.

Department of Neurology, Yokohama Brain and Spine Center, Yokohama, Japan; Department of Neurology and Stroke Center, Hiratsuka Kyosai Hospital, Hiratsuka, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.04.003DOI Listing

Prognostic nutritional index as a prognostic marker in glioblastoma: Data from a cohort of 282 Italian patients.

J Neurol Sci 2019 Apr 3;400:175-179. Epub 2019 Apr 3.

Neurological Department, ASST Lecco, Via Dell' Eremo 9-11, 23900 Lecco, Italy.

Preoperative prognostic nutritional index (PNI) is linked to the clinical outcome of patients with malignant tumours, however few studies have investigated its utility in predicting outcome in glioblastoma multiforme (GBM). We performed a retrospective study on adult patients with GBM in order to evaluate the impact of PNI on overall survival (OS), after adjusting for known prognostic factor (age, extent of surgery, Karnofsky performance status, radiochemotherapy). This is an Italian, multicentre, retrospective, cohort study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.04.002DOI Listing

Tremor in normal adults: A population-based study of 1158 adults in the Faroe Islands.

J Neurol Sci 2019 Mar 21;400:169-174. Epub 2019 Mar 21.

Department of Occupational Medicine and Public Health, The Faroese Hospital System, Tórshavn, Faroe Islands; Centre for Health Science, Faculty of Health Sciences, University of the Faroe Islands, Tórshavn, Faroe Islands.

There are virtually no population-based data on tremor in normal individuals. Using a population-based sample of 1158 normal adults ages 40-98 years in the Faroe Islands, we characterized the extent of normal action tremor across age and gender strata. Participants drew two Archimedes spirals with each hand, and tremor was systematically quantified by a senior movement disorder neurologist using a reliable and valid ordinal rating scale (ratings = 0-3). Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S0022510X193014
Publisher Site
http://dx.doi.org/10.1016/j.jns.2019.03.019DOI Listing
March 2019
11 Reads

Absence of gut microbiota during early life affects anxiolytic Behaviors and monoamine neurotransmitters system in the hippocampal of mice.

J Neurol Sci 2019 Mar 29;400:160-168. Epub 2019 Mar 29.

Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Chongqing Key Laboratory of Neurobiology, Chongqing 400016, China; Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing 400016, China. Electronic address:

The gut microbiome is composed of an enormous number of microorganisms, generally regarded as commensal bacteria. Resident gut bacteria are an important contributor to health and significant evidence suggests that the presence of healthy and diverse gut microbiota is important for normal cognitive and emotional processing. Here we measured the expression of monoamine neurotransmitter-related genes in the hippocampus of germ-free (GF) mice and specific-pathogen-free (SPF) mice to explore the effect of gut microbiota on hippocampal monoamine functioning. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.03.027DOI Listing
March 2019
2.474 Impact Factor

Motor neuron disease as a treatment responsive paraneoplastic neurological syndrome in patient with small cell lung cancer, anti-Hu antibodies and limbic encephalitis.

J Neurol Sci 2019 Mar 27;400:158-159. Epub 2019 Mar 27.

Clinical Unit of Neurology, Department of Medicine, Surgery and Health Sciences, University Hospital and Health Services of Trieste, University of Trieste, Trieste, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.03.024DOI Listing

Accurate etiology diagnosis in patients with stroke and atrial fibrillation: A role for brain natriuretic peptide.

J Neurol Sci 2019 Mar 29;400:153-157. Epub 2019 Mar 29.

Department of Neurological Science, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan.

Background: Atrial fibrillation (AF) is the leading cause of cardioembolic stroke (CES), and patients with stroke and AF are frequently assumed to have CES. However, strokes presumably due to atherosclerotic pathophysiologies in large or small vessels can also occur in patients with AF. The aims of the present study were to clarify the prevalence of and factors related to a non-cardioembolic etiology in acute stroke patients with AF. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S0022510X193015
Publisher Site
http://dx.doi.org/10.1016/j.jns.2019.03.031DOI Listing
March 2019
4 Reads

Characteristics, survival and incidence rates and trends of pilocytic astrocytoma in children in the United States; SEER-based analysis.

Authors:
Mohamed A Tabash

J Neurol Sci 2019 Mar 29;400:148-152. Epub 2019 Mar 29.

Christian Hospital Quakenbrück, Academic Teaching Hospital of the University of Oldenburg, 49610 Quakenbrück, Germany. Electronic address:

Introduction: Pilocytic astrocytoma (PA) is a neurological neoplasm and a common neurological tumor among children. No recent reports have studied the recent demographic characteristics of PA cases in the US.

Methodology: We used the Surveillance, Epidemiology, and End Results (SEER) Program to retrieve data on children diagnosed with PA between 2000 and 2015. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.03.028DOI Listing
March 2019
1 Read

A unique Japanese CPEO family with a novel homozygous m.14819 T > G (p. S25A) substitution.

J Neurol Sci 2019 Mar 29;400:145-147. Epub 2019 Mar 29.

Department of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 2-5-1 Shikatacho, Okayama 700-8558, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.03.029DOI Listing
March 2019
1 Read

Are basketball players more likely to develop Hirayama disease?

J Neurol Sci 2019 Mar 21;400:142-144. Epub 2019 Mar 21.

Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genova and IRCCS, Policlinico San Martino, Genova, Italy.

Hirayama disease is a rare neurological disease affecting primarily men in the second to third decades. To date there are only few reports from Italy. We report the case of three young basketball players who presented with clinical, electrophysiological and MRI findings suggestive for Hirayama disease. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.03.020DOI Listing

Mitochondrial metabolic stroke: Phenotype and genetics of stroke-like episodes.

Authors:
Josef Finsterer

J Neurol Sci 2019 Mar 23;400:135-141. Epub 2019 Mar 23.

Krankenanstalt Rudolfstiftung, Messerli Institute, Vienna, Austria. Electronic address:

Stroke-like episodes (SLEs) are the hallmark of mitochondrial encephalopathy with lactic acidosis and stroke-like episode (MELAS) syndrome but rarely occur also in other specific or nonspecific mitochondrial disorders. Pathophysiologically, SLLs are most likely due to a regional disruption of the blood-brain barrier triggered by the underlying metabolic defect, epileptic activity, drugs, or other factors. SLEs manifest clinically with a plethora of cerebral manifestations, which not only include features typically seen in ischemic stroke, but also headache, epilepsy, ataxia, visual impairment, vomiting, and psychiatric abnormalities. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.03.021DOI Listing
March 2019
13 Reads

Differences in the intra-cerebellar connections and graph theoretical measures between Parkinson's disease and multiple system atrophy.

J Neurol Sci 2019 Mar 25;400:129-134. Epub 2019 Mar 25.

Department of Clinical Neuroscience, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.

Background And Purpose: Parkinson's disease (PD) does not present with motor symptoms until dopaminergic neuronal loss exceeds 50%. This might indicate that a network-level compensatory mechanism involving surviving regions in PD acts to reduce brain abnormalities. In contrast, there is no evidence of a compensatory mechanism in multiple system atrophy (MSA). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.03.022DOI Listing
March 2019
2 Reads

Acid-suppressive medications and risk of pneumonia in acute stroke patients: A systematic review and meta-analysis.

J Neurol Sci 2019 Mar 13;400:122-128. Epub 2019 Mar 13.

Department of Neurology, Stroke Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.

Goal: We performed a systematic review and meta-analysis aiming to clarify the relationship between acid-suppressive medication (ASM) and the risk of pneumonia in acute stroke.

Methods: The included studies examined patients with an acute ischemic and/or hemorrhagic stroke, assessed the relationship of one or both groups of ASM, histamine-2 receptor antagonist (H2RA) and proton-pump inhibitor (PPI), as a variable of interest, and used the occurrence of hospital-acquired pneumonia (HAP) as an outcome measure. The search was conducted in MEDLINE, Cochrane, Embase, and Google Scholar. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.02.041DOI Listing
March 2019
2.474 Impact Factor

Neuronal intranuclear inclusion disease showing blepharoptosis and positive serum anti-acetylcholine receptor antibody without myasthenia gravis.

J Neurol Sci 2019 Mar 16;400:119-121. Epub 2019 Mar 16.

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.03.013DOI Listing

Ischemic stroke during anticoagulant interruption by healthcare professionals in stroke patients with atrial fibrillation.

J Neurol Sci 2019 Mar 20;400:113-118. Epub 2019 Mar 20.

Department of Neurological Science, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan.

Background: Anticoagulant therapy often requires temporary interruption. Nevertheless, the frequency and clinical characteristics of stroke patients who develop stroke during anticoagulant interruption are not fully known.

Methods: From March 2011 through May 2017, consecutive acute ischemic stroke patients with AF who were admitted to our stroke unit were retrospectively recruited. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.03.018DOI Listing
March 2019
1 Read

Motor unit potential changes in myofibrillar myopathy.

J Neurol Sci 2019 Mar 20;400:110-112. Epub 2019 Mar 20.

Laboratory of Myopathology, Department of Neurology, University of Athens, Eginition Hospital, Athens, Greece.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.03.017DOI Listing

Brief and cost-effective tool for assessing verbal learning in multiple sclerosis: Comparison of the Rey Auditory Verbal Learning Test (RAVLT) to the California Verbal Learning Test - II (CVLT-II).

J Neurol Sci 2019 Mar 19;400:104-109. Epub 2019 Mar 19.

Mandell Center for Multiple Sclerosis, Mount Sinai Rehabilitation Hospital, Trinity Health Of New England, 490 Blue Hills Avenue, Hartford, CT 06112, USA; Department of Neurology, University of Connecticut School of Medicine, Farmington, CT, USA. Electronic address:

Background: The Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) is a common cognitive screening tool. However, administration and scoring can be time-consuming, and its use of proprietary subtests like the California Verbal Learning Test - II (CVLT-II) is financially limiting. Use of the non-proprietary Rey Auditory Verbal Learning Test (RAVLT) may be provide a valid alternative. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.03.016DOI Listing
March 2019
1 Read

Hemorrhagic complications seen on immediate intraprocedural stereotactic computed tomography imaging during deep brain stimulation implantation.

J Neurol Sci 2019 Mar 14;400:97-103. Epub 2019 Mar 14.

Department of Neurosurgery, Bródno Mazovia Hospital, Warsaw, Poland, Kondratowicza 8 Street, 03-242 Warsaw, Poland.

Background: We present our operative experience of patients with movement disorders who developed intracerebral hemorrhage (ICH), which was identified on intraprocedural stereotactic computed tomography (CT) imaging performed immediately after deep brain stimulation (DBS) lead placement and prior to the implantation of further components of the DBS hardware.

Methods: Patients who underwent DBS lead implantation from January 2009 through December 2017 were included in the present study. Most of the surgeries were performed in a staged fashion. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.01.033DOI Listing
March 2019
1 Read

Effect of short-term transcutaneous trigeminal nerve stimulation on EEG activity in drug-resistant epilepsy.

J Neurol Sci 2019 Mar 14;400:90-96. Epub 2019 Mar 14.

Department of Biomedical Sciences, University of Sassari, Viale San Pietro 43/b, 07100 Sassari, Italy. Electronic address:

Background: Transcutaneous trigeminal nerve stimulation (TNS) has antiepileptic effects in patients with drug-resistant epilepsy (DRE). However, whether and how TNS is able to modulate the electroencephalogram (EEG) background activity in patients with DRE is still unknown.

Objectives: To investigate the effect of short-term TNS on EEG background activity in DRE by qualitative and quantitative analyses. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.03.004DOI Listing
March 2019
1 Read

Clinical characteristics and outcomes of myelin oligodendrocyte glycoprotein antibody-seropositive optic neuritis in varying age groups: A cohort study in China.

J Neurol Sci 2019 Mar 16;400:83-89. Epub 2019 Mar 16.

Department of Ophthalmology, Chinese PLA General Hospital, Fuxing Road No.28, Haidian district, Beijing 100853, China. Electronic address:

Purpose: To investigate the clinical characteristics and outcomes of myelin oligodendrocyte glycoprotein antibody-seropositive optic neuritis (MOG-ON) in patients with varying ages of onset in China.

Methods: Patients displaying symptoms of MOG-ON were recruited from the Neuro-ophthalmology Department in the Chinese People's Liberation Army General Hospital from January 2016 to May 2018. They were assigned to one of three subgroups based on age of onset: pediatric (<18 years), young (18-46 years), and middle-aged (>46 years) MOG-ON. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.03.014DOI Listing

The progress of neuronal autophagy in cerebral ischemia stroke: Mechanisms, roles and research methods.

J Neurol Sci 2019 Mar 16;400:72-82. Epub 2019 Mar 16.

State Key Laboratory of Natural Medicines, Department of Physiology, China Pharmaceutical University, Nanjing 210009, China. Electronic address:

There is increasing evidence indicating that autophagy may be a new target in the treatment of ischemic stroke. Moderate autophagy can clear damaged organelles, thereby protecting cells against various injuries. However, long-term excessive autophagy brings redundant degradation of cell contents, leading to cell death and eventually serious damage to tissues and organs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.03.015DOI Listing

Evaluation of MS related central fatigue using MR neuroimaging methods: Scoping review.

J Neurol Sci 2019 Mar 14;400:52-71. Epub 2019 Mar 14.

School of Health Sciences, Faculty of Health and Medicine, University of Newcastle, Callaghan, NSW 2308, Australia; Hunter Medical Research Institute, Kookaburra Circuit, New Lambton Heights, NSW 2305, Australia. Electronic address:

Background: Fatigue is a common and debilitating symptom in multiple sclerosis (MS). Over the past decade, a growing body of research has focussed on the pathophysiological mechanisms underlying central (cognitive and physical) fatigue in MS. The precise mechanisms causing fatigue in MS patients are complex and poorly understood, and may differ between patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.03.007DOI Listing
March 2019
1 Read
2.474 Impact Factor

Comparative study on clinical, laboratory and electrodiagnostic findings of peripheral neuropathy in patients with hypocupremia and hypercupremia, and literature review.

J Neurol Sci 2019 Mar 15;400:47-51. Epub 2019 Mar 15.

Department of Pharmacology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, United States of America.

Copper deficiency (hypocupremia) or toxicosis (hypercupremia) may cause disorders of central and peripheral nervous systems. Hypocupremia causes myeloneuropathy resembling vitamin B12 deficiency. However, the clinical manifestations, particularly peripheral neuropathy (PN), of hypercupremia have not been adequately evaluated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.03.012DOI Listing
March 2019
2.474 Impact Factor

Status dystonicus in pantothenate kinase-associated neurodegeneration due to internal pulse generator depletion: Case study and literature review.

J Neurol Sci 2019 Feb 28;400:44-46. Epub 2019 Feb 28.

Department of Neurology, Institute of Neurology, RuiJin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Laboratory of Neurodegenerative Diseases & Key Laboratory of Stem Cell Biology, Institute of Health Science, Shanghai Institutes for Biological Sciences (SIBS), Chinese Academy of Sciences (CAS), Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.02.038DOI Listing
February 2019
1 Read

Whipple's endocarditis diagnosed by thrombus analysis retrieved by successful mechanical thrombectomy.

J Neurol Sci 2019 Mar 14;400:42-43. Epub 2019 Mar 14.

Stroke Unit, Department of Neurology, Hôpital Pierre Wertheimer, Lyon, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.03.009DOI Listing
March 2019
1 Read

Expanding the clinical description of autosomal recessive spastic ataxia of Charlevoix-Saguenay.

J Neurol Sci 2019 Mar 12;400:39-41. Epub 2019 Mar 12.

Centre de recherche Charles-Le-Moyne-Saguenay-Lac-Saint-Jean sur les innovations en santé, Faculté de médecine et des sciences de la santé, Université de Sherbrooke, Sherbrooke, Québec, Canada; Groupe de recherche interdisciplinaire sur les maladies neuromusculaires, Centre intégré universitaire de santé et de services sociaux du Saguenay-Lac-St-Jean, Jonquière, Québec, Canada. Electronic address:

Background And Purpose: Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) diagnosis is based on the presence of three main clinical features: 1) ataxia, 2) pyramidal involvement, and 3) axonal neuropathy. This study aimed to explore, among a cohort of adults with ARSACS, the prevalence of other signs and symptoms than those commonly describe in this disease and compare their prevalence between younger (<40 years) and older (≥40 years) participants.

Methods: A clinical interview based on a standardized questionnaire was conducted. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.03.008DOI Listing
March 2019
1 Read

Seizures in patents with primary central nervous system lymphoma: Prevalence and associated features.

J Neurol Sci 2019 Mar 14;400:34-38. Epub 2019 Mar 14.

Department of Neurology, Medical University of South Carolina, Charleston, SC, USA.

Objective: Primary central nervous system (CNS) lymphoma (PCNSL) is a rare, aggressive, yet highly chemosensitive form of non-Hodgkin lymphoma which is associated with significant morbidity. Very little is known about the long-term risk for and features of seizures associated with this condition.

Methods: We performed a retrospective and longitudinal analysis of 36 patients with pathologically and radiographically confirmed primary CNS lymphoma to evaluate the incidence, prevalence and features associated with seizures. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.03.011DOI Listing
March 2019
2 Reads

Stenotrophomonas maltophilia brain abscesses after implantation of motor cortex stimulator.

J Neurol Sci 2019 Mar 14;400:32-33. Epub 2019 Mar 14.

Department of Neurology, University Hospital, Ludwig-Maximilians-University, Munich, Germany.

We describe the first case of a patient with brain abscesses caused by Stenotrophomonas maltophilia as a complication after motor cortex stimulator implantation. Brain abscesses pose a challenge in diagnosis and treatment, because microbiological diagnosis is not always achieved, antibiotic drugs may not penetrate well into the CNS and some bacteria have resistances to typical empirical antibiotic drugs. In this case diagnosis was only made after removal of the stimulator and a long term treatment with antibiotic drugs was necessary. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.03.010DOI Listing
March 2019
1 Read

The multifactorial etiology of stroke-associated pneumonia.

J Neurol Sci 2019 Mar 12;400:30-31. Epub 2019 Mar 12.

Department of Neurology, University of Lübeck, Lübeck, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.02.042DOI Listing

The severity of motor dysfunctions and urinary dysfunction is not correlated in multiple system atrophy.

J Neurol Sci 2019 Mar 12;400:25-29. Epub 2019 Mar 12.

Department of Neurology, Chiba University Graduate School of Medicine, Chiba, Japan.

Objective: Although it is well known that patients with multiple system atrophy (MSA) cerebellar dominant type (MSA-C) show severe autonomic dysfunction, the relationship between autonomic and motor dysfunction remains uncertain. Previously we reported that severe urinary voiding dysfunction is useful in differential diagnosis of MSA and other diseases. Herein, we aimed to clarify the relationship between the severity of motor dysfunctions and urinary dysfunction. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.03.005DOI Listing
March 2019
2 Reads

Early radiological features of severe longitudinally extensive transverse myelitis over time.

J Neurol Sci 2019 Feb 4;400:7-9. Epub 2019 Feb 4.

Department of Neurology, AP-HP, Pitié-Salpêtrière Hospital, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.01.043DOI Listing
February 2019

Selective vulnerability in neurodegenerative diseases is not easily reconcilable with clinical diversity and clinical-anatomical convergence.

Authors:
Carlo Abbate

J Neurol Sci 2019 Mar 11;400:23-24. Epub 2019 Mar 11.

Geriatric Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, via Alfonso Lamarmora 5, 20122, Milan, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.03.003DOI Listing
March 2019
1 Read

A case of cerebral infarction in a patient with TAFRO syndrome.

J Neurol Sci 2019 Mar 12;400:21-22. Epub 2019 Mar 12.

Department of Stroke Medicine, Kawasaki Medical School, Okayama, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.03.006DOI Listing
March 2019
1 Read

MR microneurography and quantitative T2 and DP measurements of the distal tibial nerve in CIDP.

J Neurol Sci 2019 Mar 11;400:15-20. Epub 2019 Mar 11.

Department of Neuroradiology, C. Mondino National Neurological Institute, Pavia, Italy; Department of Brain and Behavioral Sciences, University of Pavia, Pavia, PV, Italy.

Objective: In this study we investigated the potential of magnetic resonance (MR) micro-neurography to detect morphological and relaxometric changes in distal tibial nerves in patients affected with chronic inflammatory demyelinating polyneuropathy (CIDP), and their associations with clinical and electrophysiological features.

Materials And Methods: 10 subjects affected with CIDP and 10 healthy subjects were examined. Multiple MR parameters, including the number of fascicles (N), fascicles diameter (FD), total fascicles area (FA), epineurium area (EA), total nerve area (NA), fascicles to nerve ratio (FNR) and quantitative T2 and proton density (PD) were investigated on high resolution MR images of the distal tibial nerve. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.03.001DOI Listing

Cerebral infarct topography of atrial fibrillation and Chagas disease.

J Neurol Sci 2019 Mar 12;400:10-14. Epub 2019 Mar 12.

Universidade Federal Fluminense, D'Or Institute for Research and Education, Rio de Janeiro, Brazil.

Background: Chagas disease (CD) and ischemic stroke (IS) have a significant but poorly understood correlation. There is paucity of evidence regarding secondary prophylaxis of IS and etiological causes.

Objectives: To compare arterial stroke topography and the respective morbidities and mortality in patients with CD of undetermined and cardioembolic etiologies and with cardioembolic IS (atrial fibrillation [AF]). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.03.002DOI Listing
March 2019
1 Read

Stroke mechanisms and their correlation with functional outcome in medullary infarction.

J Neurol Sci 2019 Mar 1;400:1-6. Epub 2019 Mar 1.

Department of Neurology, Kyoto Prefectural University of Medicine, Japan. Electronic address:

Purpose: To study the stroke mechanism of medullary infarction (MI) and their correlation with prognosis.

Methods: We collected 81 consecutive patients with acute isolated MI including 50 patients with lateral MI (LMI), 30 with medial MI (MMI) and one with combined MI. The stroke mechanisms were defined as follows: 1. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.02.039DOI Listing
March 2019
2 Reads

Genetics of amyotrophic lateral sclerosis: A review.

J Neurol Sci 2019 Apr 21;399:217-226. Epub 2019 Feb 21.

Department of Neurology, Nerve-Muscle Unit, CHU Bordeaux, (Pellegrin Hospital), University of Bordeaux, F-33000 Bordeaux, France; Neurocentre Magendie, 'Physiopathologie de la Plasticité Neuronale', University of Bordeaux, U862, F-33000 Bordeaux, France; INSERM, Neurocentre Magendie, 'Physiopathologie de la Plasticité Neuronale', U862, F-33000 Bordeaux, France.

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder of the motor pathways, invariably leading to death within a few years of onset. Most cases of ALS are sporadic, but familial forms of the disease (FALS) constitute 10% of the cases. Since the first identification of a causative gene in the 1990s and with recent advances in genetics, more than twenty genes have now been linked to FALS. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.02.030DOI Listing
April 2019
2 Reads

A novel CACNA1A nonsense variant in a patient presenting with paroxysmal exertion-induced dyskinesia.

J Neurol Sci 2019 Apr 1;399:214-216. Epub 2019 Mar 1.

Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Matsumoto 390-8621, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.02.040DOI Listing

Age, sex, and setting in the etiology of stroke study (ASSESS): Study design and protocol.

J Neurol Sci 2019 Apr 14;399:209-213. Epub 2019 Feb 14.

Department of Clinical Neurological Sciences, University Hospital, London Health Sciences Center, Western University, ON, Canada; Department of Epidemiology and Biostatistics, Western University, ON, Canada. Electronic address:

Rationale: Stroke etiology and risk factors vary by age, sex, setting (hospital or community-based) and by region. Identifying these differences would improve our understanding of stroke etiology, diagnosis, and treatment.

Aim: The Age, Sex and Setting in the Etiology of Stroke Study (ASSESS) is a multicenter cohort study to assess differences in stroke etiology. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.02.024DOI Listing
April 2019
7 Reads

Response to letter of "hemoglobin level as a predictor of clinical outcome in patients with ischemic stroke" by Tomoyuki Kawada.

J Neurol Sci 2019 Apr 26;399:207-208. Epub 2019 Feb 26.

Department of Epidemiology, School of Public Health, Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, Medical College of Soochow University, Suzhou, Jiangsu, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.02.035DOI Listing
April 2019
2 Reads

Comparative efficacy and safety of multiple antiplatelet therapies for secondary prevention of ischemic stroke or transient ischemic attack: A network meta-analysis.

J Neurol Sci 2019 Apr 27;399:199-206. Epub 2019 Feb 27.

Department of Clinical Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning, China.

Background: Antiplatelet therapies for secondary prevention of ischemic stroke or transient ischemic attack (TIA) is a highly active research topic with five critical drugs obtained by visual analysis. We aimed to compare and rank multiple antiplatelet therapies using a network meta-analysis.

Methods: Relevant medical databases were searched. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.02.037DOI Listing
April 2019
6 Reads

Apathy in Parkinson's disease with REM sleep behavior disorder.

J Neurol Sci 2019 Apr 20;399:194-198. Epub 2019 Feb 20.

Sleep-Wake-Epilepsy Center, Department of Neurology, University Hospital (Inselspital) and University of Bern, Bern, Switzerland.

Objectives: Rapid eye movement (REM) sleep behavior disorder (RBD) in patients with Parkinson's disease (PD) is associated with increased risk of non-motor symptoms. However, the association between RBD and apathy in PD remains unclear.

Aims: To compare the prevalence and severity of apathy symptoms in PD patients with RBD (PD-RBD+) and without (PD-RBD-). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.02.028DOI Listing
April 2019
1 Read

Mobility improves after high intensity aerobic exercise in individuals with Parkinson's disease.

J Neurol Sci 2019 Apr 21;399:187-193. Epub 2019 Feb 21.

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, United States of America; Center for Neurological Restoration, Cleveland Clinic, Cleveland, OH, United States of America; Cleveland Clinic Concussion Center, Cleveland Clinic, Cleveland, OH, United States of America. Electronic address:

Emerging literature indicates aerobic exercise improves the motor symptoms associated with Parkinson's disease (PD). However, the impact of aerobic exercise on functional locomotor performance has not been evaluated systematically. The aim of this project was to determine the impact of an 8-week high intensity aerobic exercise intervention on Timed Up and Go (TUG) performance in PD. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2019.02.031DOI Listing
April 2019
1 Read