11,336 results match your criteria Journal of the Medical Association of Thailand[Journal]


Population Pharmacokinetics and Pharmacodynamics Modeling of Oral Levofloxacin.

J Med Assoc Thai 2018 Aug;99(8):886-92

Background: Levofloxacin, a fluoroquinolone, is an isomer of ofloxacin with an extensive spectrum of antimicrobial efficacy. In common with other fluoroquinolones, the main pharmacokinetic/pharmacodynamic (PK/PD) index that correlates with its therapeutic efficacy is the area under the plasma time-concentration curve (AUC)/the minimum inhibitory concentration (MIC) ratios.

Objective: To evaluate the population PK and determine the efficacy of various dosage regimens in achieving the probability of target attainment (PTA) and the cumulative fraction of response (CFR) of oral levofloxacin when prescribed as the switching therapy after intravenous levofloxacin treatment. Read More

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August 2018
22 Reads

The Effect of Home Buddhist Mindfulness Meditation on Depressive Symptom in Major Depressive Patients.

J Med Assoc Thai 2017 Nov;99 Suppl 8:S171-S178

Background: Major depressive disorder (MDD) is the important cause of disability in the world. Major depressive patients that are not respond to the first and second drugs are about 67% and 33%, respectively. Therefore the effective treatment is urgently needed. Read More

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November 2017
1 Read

Monitoring HIV Drug Resistance: Early Warning Indicators to Assess Performance of Thailand's Antiretroviral Treatment Program.

J Med Assoc Thai 2017 Sep;100(9):944-952

Department of Disease Control, Thailand Ministry of Public Health, Nonthaburi, Thailand.

Objective: To describe trends in Thailand's antiretroviral treatment (ART) program performance assessed by HIV drug resistance early warning indicators (EWIs), as recommended by WHO, between 2009 and 2013.

Material And Method: Seven EWIs were monitored, viral load (VL) testing coverage, VL suppression, retention in ART, lost to follow-up (LTFU), antiretrovirals (ARVs) dispensing practices, on-time pill pick-up, and pharmacy stock-outs. Data from ART adult patients in National Health Security Office Scheme were analyzed except for pharmacy stock-outs, which were reported from hospitals. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978419PMC
September 2017
6 Reads

In vitro Activity of Sitafloxacin and Other Antibiotics against Bacterial Isolates from HRH Princess Maha Chakri Sirindhorn Medical Center, Srinakharinwirot University and Samitivej Sukhumvit Hospital.

J Med Assoc Thai 2017 Apr;100(4):469-78

Background: Sitafloxacin is a newly approved oral fluoroquinolone in Thailand for treatment of respiratory tract and urinary tract infections. Initial in vitro susceptibility testing showed its effect on Escherichia coli with extended-spectrum betalactamases (ESBL), Klebsiella pneumoniae with ESBL, Pseudomonas aeruginosa, and carbapenem resistant Acinetobacter baumannii

Objective: To retrospectively review in vitro susceptibility to sitafloxacin on clinical isolates from HRH Princess Maha Chakri Sirindhorn Medical Center, Srinakharinwirot University (SWU) and Samitivej Sukhumvit Hospital (SVH).

Material And Method: Between January 2014 and June 2015, all clinical isolates from SWU and SVH that were added to test in vitro susceptibility to sitafloxacin were included in the present study. Read More

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April 2017
2 Reads

Risk Factors of Post-operative Sore Throat and Hoarseness.

J Med Assoc Thai 2017 Apr;100(4):463-8

Objective: To identify the risk factors of post-operative sore throat (POST) with and without hoarseness (PH) after general anesthesia.

Material And Method: A retrospective cohort case-controlled study was done at Siriraj Hospital, Mahidol University, Bangkok, Thailand. Two thousand six hundred anesthetic records from between July 2013 and January 2014 were retrieved. Read More

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April 2017
1 Read

Reliability of Registration in Imageless Navigation Total Hip Arthroplasty in Semilateral Decubitus Position.

J Med Assoc Thai 2017 Apr;100(4):457-62

Background: One of the limitations in imageless navigation is the variability in bony landmark registration among surgeons. If the bony landmark registration is different among surgeons, the final cup position determined by the navigation will also be different.

Objective: To determine intra and inter-observer reliability of the bony landmark registration in three surgeons with varying experience in imageless navigation total hip arthroplasty (THA) in semilateral decubitus position. Read More

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April 2017
1 Read

A Comparative of Ginger Extract in Nanostructure Lipid Carrier (NLC) and 1% Diclofenac Gel for Treatment of Knee Osteoarthritis (OA).

J Med Assoc Thai 2017 Apr;100(4):447-56

Objective: To compare and evaluate the efficacy of ginger (Zingiber officinale Roscoe) extracts in NLC for treatment of osteoarthritis of knee compared to 1% diclofenac gel as an active control.

Material And Method: One hundred twenty patients age 50 to 75 years with OA knee, based on the American College of Rheumatology (ACR) criteria were randomized into two groups receiving ginger extracts in NLC and control 1% diclofenac gel for 12 weeks. The efficacy of treatment was monitored at 4, 8, and 12 weeks by using the WOMAC composite index and the Patient Global Assessment (PGA). Read More

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April 2017
1 Read

Pilot Clinical Evaluation of PoreSkin: A Human Acellular Dermal Matrix in Burn Scars.

J Med Assoc Thai 2017 Apr;100(4):441-6

Background: An extensive full-thickness wound need a graft, sometime very large. However, donor sites are often limited. Dermal substitutes are among the tissue-engineered products applied to clinical use. Read More

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April 2017
16 Reads

Improving the Surgical Outcomes after Liver Resection with ERAS Program.

J Med Assoc Thai 2017 Apr;100(4):435-40

Background: Enhanced recovery after surgery (ERAS) has been accepted as the program to improve the surgical outcomes. This program has been increasingly utilized in liver resection.

Objective: To evaluate the outcomes of patients underwent liver resection by applying ERAS program. Read More

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April 2017
6 Reads

The Optimal Predictors of Readiness for Extubation in Low Birth Weight Infants.

J Med Assoc Thai 2017 Apr;100(4):427-34

Background: Reintubation, following an unsuccessful extubation from mechanical ventilation is traumatic to the infant and the family. However, 20 to 40% of infants fail extubation and reintubation.

Objective: Determine the optimal predictors of readiness for extubation in low birth weight infants during endotracheal tubecontinuous positive airway pressure (ET CPAP) for three minutes. Read More

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April 2017
4 Reads

Attention Deficit Hyperactivity Disorder (ADHD): Clinical Outcomes Measurement Development.

J Med Assoc Thai 2017 Apr;100(4):418-26

Objective: To develop a reliable and valid treatment outcome checklist for the measurement of ADHD treatment for children in a clinical setting.

Material And Method: The behavior indicators to assess the treatment outcomes of ADHD children were researched and developed by using multi-informants perspectives. The present study involved a qualitative study and two rounds of the Modified Delphi Techniques. Read More

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April 2017
1 Read

Effects of Stroke Unit Care in Acute Ischemic Stroke Patient Ineligible for Thrombolytic Treatment.

J Med Assoc Thai 2017 Apr;100(4):410-7

Background: Several trials have verified the benefits of stroke unit (SU) in acute stroke care worldwide.

Objective: Compare clinical outcomes and costs of care in acute ischemic stroke patients who were ineligible for thrombolytic treatment (recombinant tissue plasminogen activator-rt PA) in a primary stroke center.

Material And Method: A prospective study was conducted in acute ischemic stroke patients, aged 15 years old and above, presenting within 72 hours of onset. Read More

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April 2017
1 Read

Descriptors of Insomnia among Patients with Heart Failure.

J Med Assoc Thai 2017 Apr;100(4):403-9

Objective: Explore the characteristics of insomnia in persons with heart failure and identify the predictive factors of insomnia in patients with heart failure.

Marital And Method: A predictive correlational research design was used. Three hundred forty heart failure patients followed-up at heart clinics, outpatient departments of 10 tertiary hospitals from all regions in Thailand, were selected by multi-stage random sampling. Read More

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April 2017
1 Read

A Study of Interleukin-2 Production and Nck Adaptor Molecule Gene Expression in Systemic Lupus Erythematosus Patients.

J Med Assoc Thai 2017 Apr;100(4):396-402

Background: Systemic lupus erythematosus (SLE) is an autoimmune disease. The cause of the disease is related to multiple factors and involves immune responses. To the best of our knowledge, the relationship between the production of interleukin-2 (IL-2) and Nck adaptor molecule gene expression by lymphocytes in patients with SLE has not been studied. Read More

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April 2017
5 Reads

A Clinical Risk Score for Predicting Paraspinal Extramedullary Hematopoiesis in Patients with Thalassemia: The KKU-EMH Score.

J Med Assoc Thai 2017 Apr;100(4):389-95

Background: Paraspinal extramedullary hematopoiesis (EMH) is uncommon, but it is one of major complications of increased morbidity in patients with thalassemia.

Objective: To develop a clinical risk score for predicting paraspinal extramedullary hematopoiesis in patients with thalassemia.

Material And Method: A retrospective study was conducted in adult patients with thalassemia at Srinagarind Hospital, Khon Kaen University (KKU) and Udonthani Hospital, Thailand. Read More

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April 2017
1 Read

Risk Score for Prediction of Postpartum Hemorrhages in Normal Labor at Chonburi Hospital.

J Med Assoc Thai 2017 Apr;100(4):382-8

Background: Postpartum hemorrhage (PPH) is major cause of morbidity and mortality globally. Although the majority of PPH could be avoided through the use of pharmacologic prevention during the third stage of labor, the maternal mortality rate from PPH is unchanged and the blood transfusion rate is increasing. In rural hospital or primary care unit, most health care workers are general practitioners and intern doctors, they are inexperienced in managing PPH case and lack of medication, blood component, medical instrument, and surgical team. Read More

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April 2017
10 Reads

Effect of Supportive Information on Anxiety Levels in Pregnant Women Awaiting Amniocentesis Results: A Randomized Controlled Trial.

J Med Assoc Thai 2017 Apr;100(4):374-81

Objective: To evaluate the effect of supportive information on anxiety levels in women awaiting amniocentesis results.

Material And Method: Women underwent amniocentesis were randomized into two groups according to whether they did (group A) or did not (group B) receive supportive information. Anxiety levels were measured using the Spielberger State-Trait Anxiety Inventory at four time points, (1) after amniocentesis, (2) before phoning for test result appointment confirmation, (3) after phoning, during which supportive information was given to group A, and (4) before receiving the test results. Read More

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April 2017
2 Reads

Association Between Intrapartum Cardiotocogram and Early Neonatal Outcomes in a Tertiary Hospital in Thailand.

J Med Assoc Thai 2017 Apr;100(4):365-73

Background: Intrapartum electronic fetal monitoring (EFM) has widely been used to monitor mothers in labor who are at risk in clinical practice. There is little evidence to describe the association between EFM categories based on the newly proposed National Institute of Child Health and Human Development (NICHD) 2008 criteria and neonatal outcomes.

Objective: To investigate the association between intrapartum cardiotocogram categories based on the NICHD 2008 and early neonatal outcomes

Material And Method: Intrapartum EFM tracings of 120 singleton pregnant women of equal or more than week gestation were evaluated according to NICHD 2008 guidelines. Read More

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April 2017
1 Read

Two-Hour Nasal Responses after a Single Dose of Ephedrine Nasal Spray in Healthy Males.

J Med Assoc Thai 2017 Mar;100(3):358-64

Background: Ephedrine is often used as nasal decongestant. Yet, the clinical study of intranasal ephedrine is scarce. In addition, the study tools may affect the measurement of the nasal patency. Read More

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March 2017
2 Reads

Predicting Factors in Identifying Cognitive Decline among Thai Adults.

J Med Assoc Thai 2017 Mar;100(3):353-7

Objective: To evaluate the clinical factors that associated with cognitive decline among Thai adults.

Material And Method: The cross-sectional study was performed between March 2015 and September 2015 at The Princess of Naradhiwas Memorial Hospital. Three hundred ten Thai government officers received annual health check-ups according to standard government protocol. Read More

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March 2017
1 Read

Influence of Rehabilitation Medicine Residency Training in Performing Chemodenervation in Children with Cerebral Palsy in Thailand.

J Med Assoc Thai 2017 Mar;100(3):347-52

Background: Chemodenervation (CD) involves injecting drugs such as phenol, botulinum toxin, or alcohol to reduce muscle spasticity. However, they interfere with daily activities of children with cerebral palsy (CP). Rehabilitation residency training in Thailand currently requires performing a minimum of five CD procedures. Read More

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March 2017
2 Reads

Impact of Tobacco Control Campaigns on Smoking Behaviors in Thai Medical Schools.

J Med Assoc Thai 2017 Mar;100(3):339-46

Objective: To explore the changes in the prevalence of smoking behavior, attitudes, and cessation training among medical students after the establishment of the Thai Health Professional Alliance against Tobacco (ThaiPAT) and its major campaigns by using the nationwide Global Health Professions Student Surveys (GHPSS).

Material And Method: Multiple cross-sectional studies were conducted after three major campaigns were launched between 2007 and 2011, the Deans’ Summit on Tobacco Control, implemented tobacco control into the medical curriculum, and 100% smoke-free hospitals and medical schools. The results of two rounds of GHPSS among third year medical students across the nation in 2006 and 2011 were compared. Read More

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March 2017
1 Read

Identification of Potential Leverage Points for Self-Management Support Intervention in Thais with Type 2 Diabetes.

J Med Assoc Thai 2017 Mar;100(3):326-38

Background: Although social-ecological models and multi-level interventions have been recommended for implementing the holistic self-management support for patients with type 2 diabetes, they are complex, costly, and need long-term effort. A more realistic approach would be to identify and implement a single or limited leverage point(s) that is most effective and feasible to create change.

Objective: To assess the independent relationships of the social-environmental supports with self-management behaviors in Thai patients with type 2 diabetes. Read More

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March 2017
7 Reads

Exercise Intensity and Substrate Utilization in Healthy Sedentary Females Using the Life-Build-Line Device.

J Med Assoc Thai 2017 Mar;100(3):318-25

Background: Life-Build-Line (LBL) is a new exercise device that is convenient, and not so expensive. Together with the style of movement, it may boost one to adhere to the exercise regimen and thereby promote better health. However, no study has proved its exercise intensity and effect on substrate utilization. Read More

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March 2017
21 Reads

Management Outcome of Severe Laryngomalacia at Queen Sirikit National Institute Child Health.

J Med Assoc Thai 2017 Mar;100(3):313-7

Background: Outcomes of the different management in severe laryngomalacia (LM) have not been evaluated.

Objective: To identify the management practices and to evaluate the outcomes in patient with severe LM.

Material And Method: The medical records of LM at Queen Sirikit National Institute Child Health between January2007 and December 2012 were retrospectively reviewed. Read More

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March 2017
2 Reads

Comparison of Intubation Time with GlideScope® and McIntosh Laryngoscope in Obese Patients

J Med Assoc Thai 2017 Mar;100(3):306-12

Background: Difficult intubation is more frequent in obese than in lean patients. The GlideScope® is a videolaryngoscope that provides a laryngoscopic view equal to or better than a direct laryngoscope in non-obese patients.

Objective: To compare the intubation time between the GlideScope® and the McIntosh laryngoscope in obese patients. Read More

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March 2017
1 Read

Outcome of Single Event Multilevel Soft Tissue Release for Spastic Diplegic Cerebral Palsy.

J Med Assoc Thai 2017 Mar;100(3):301-5

Objective: We evaluated the results of single event multilevel surgery for treatment of contractures of lower extremities in spastic diplegic cerebral palsy patients in Phramongkutklao Hospital.

Material And Method: The present study included 40 patients (23 boys, 17 girls, mean age 8.9 years) with spastic diplegic cerebral palsy, who underwent single event multilevel surgery for the treatment of soft tissue contractures in lower extremities secondary to spasticity between 2006 and 2009. Read More

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March 2017
1 Read

Lateral Release Can Increase Range of Flexion during Computer Assisted Total Knee Arthroplasty with Patellar Maltracking.

J Med Assoc Thai 2017 Mar;100(3):295-300

Objective: The patellar tracking is an important factor that affect range of motion after total knee arthroplasty (TKA). Intraoperative patellar maltracking during TKA can be improved by performing lateral release. We hypothesized that TKA with patellar maltracking after undergoing lateral release can increase intraoperative range of flexion. Read More

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March 2017
1 Read

A Comparison between Modified Robert Jones Bandage and Intermittent Cold Pack in Arthroscopic Anterior Cruciate Ligament Reconstruction: A Prospective Randomized Controlled Trial.

J Med Assoc Thai 2017 Mar;100(3):287-94

Background: Modified Robert Jones bandage and intermittent cold pack are commonly used for postoperative care in arthroscopic anterior cruciate ligament reconstruction (ACLR). However, no study has been done to compare the postoperative pain and functional outcome of both methods in ACLR.

Objective: To compare the postoperative pain and functional outcome of a modified Robert Jones bandage and intermittent cold pack in ACLR. Read More

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March 2017
2 Reads

Efficacy of Botulinum Toxin A in Preventing Recurrence Keloids: Double Blinded Randomized Controlled Trial Study: Intraindividual Subject.

J Med Assoc Thai 2017 Mar;100(3):280-6

Background: Keloids have been one of the most concerning problems in cosmetic surgery. Current treatments still provide unpredictable outcomes. Interestingly, one molecular study of Botulinum Toxin A (BTXA) has found the inhibitive effect of fibroblast growth factor (TGF-β), which explain the mechanism of keloid formation. Read More

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March 2017
25 Reads

Demographics and Outcomes of Percutaneous Coronary Intervention in Thailand: Data from Thai Percutaneous Coronary Intervention Registry.

J Med Assoc Thai 2017 Mar;100(3):270-9

Background: Percutaneous coronary intervention (PCI) has been and continues to be standard treatment in patients with coronary artery disease. The data for demographic and outcomes in Thailand are limited.

Objective: To study data and characteristics relating to patients, the procedure, and outcomes of percutaneous coronary intervention in the Thai population. Read More

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March 2017
3 Reads

Clinical Characteristics and Treatment Response of Chronic Inflammatory Demyelinating Polyradiculoneuropathy.

J Med Assoc Thai 2017 Mar;100(3):262-9

Background: The incidence, prevalence, clinical phenotypes, and treatment response of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) are varying in the world literature. There have been no epidemiologic studies of CIDP in Thai adult patients.

Objective: To determine clinical characteristics, phenotypes, electrophysiological tests, and treatment response of CIDP in Thai adult patients and to find factors associated with disease outcome after treatment. Read More

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March 2017
24 Reads

The Association of Breastfeeding Practices with Neonatal Jaundice.

J Med Assoc Thai 2017 Mar;100(3):255-61

Background: Neonatal jaundice is a common problem in newborns. Inadequate breastfeeding jaundice is an important consideration for the neonatal jaundice. Early breastfeeding initiation and good breastfeeding practices may help to prevent neonatal jaundice. Read More

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March 2017
1 Read

Gestational Gigantomastia: A Case Report.

J Med Assoc Thai 2017 Feb;100 Suppl 1:S230-3

Gestational gigantomastia is a rare disorder characterized by rapidly progressive hypertrophy of the breast tissue during pregnancy. Its prevalence is approximately 1:100,000, and although the etiology of this condition remains unclear, it may be related to hormonal change. This study reports the case of a 39-year-old pregnant woman at 22 weeks of gestation with massive enlargement of bilateral breasts (gigantomastia) and presents the sonographic findings of this rare condition which shows different parenchymal patterns from those of normal breasts and is uncommonly seen. Read More

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February 2017
11 Reads

Breakfast Skipping among Personnel in Rajavithi Hospital.

J Med Assoc Thai 2017 Feb;100 Suppl 1:S222-9

Background: Breakfast skipping is considered to be an unhealthy eating habit and is linked with several health issues, including obesity, type 2 diabetes mellitus, and metabolic syndrome (MetS). Few studies on the breakfast consumption habits of hospital personnel have been carried out.

Objective: This study aimed to determine the prevalence of breakfast skipping among Rajavithi Hospital personnel. Read More

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February 2017
25 Reads

Sleep Quality among Residents and Fellows in Rajavithi Hospital.

J Med Assoc Thai 2017 Feb;100 Suppl 1:S205-11

Background: Sleep is one of the basic needs of human beings and is important to their health. Medicine is one of the most stressful fields of education because of its highly demanding professional and academic requirements, and psychological stress and poor sleep are highly prevalent in resident and fellowship training; however, they are not well documented and have not yet been taken seriously.

Objective: This study aimed to determine the prevalence of poor sleep and associated factors in resident and fellowship training in Rajavithi Hospital, a tertiary referral hospital in Bangkok, Thailand. Read More

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February 2017
1 Read

Complications and Outcomes in Breast Reconstruction using A Transverse Rectus Abdominis Myocutaneous Flap-Single Surgeon Experience.

J Med Assoc Thai 2017 Feb;100 Suppl 1:S200-4

Background: Breast cancer is the most common cancer in Thai women. Current treatments of breast cancer aim not only at complete cure but also at maintaining the patients’ quality of life. Mastectomy is still a standard procedure for removal of cancer, but nowadays the patient has many modalities to choose from in order to achieve cosmetic satisfaction. Read More

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February 2017
3 Reads

Early Diagnosis of Necrotizing Fasciitis using Laboratory Risk Indicator of Necrotizing Fasciitis (LRINEC) Score.

J Med Assoc Thai 2017 Feb;100 Suppl 1:S192-9

Background: Necrotizing fasciitis (NF) is a rapidly progressive inflammatory infection of the fascia. Early diagnosis of NF is essential, as delayed diagnosis leads to higher rates of amputation and mortality. The laboratory risk indicator for necrotizing fasciitis (LRINEC) score is used to obtain early diagnosis in order to reduce morbidity and mortality rates. Read More

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February 2017
2 Reads

Success Rates and their Related Factors in Patients Receiving Radioiodine (I-131) Treatment for Hyperthyroidism.

J Med Assoc Thai 2017 Feb;100 Suppl 1:S183-91

Background And Objective: The success rate of I-131 therapy for hyperthyroidism is dependent on several factors. The aim of the present study was to evaluate the success rates, and the factors which affected them, in patients with hyperthyroidism at Rajavithi Hospital who received I-131 therapy with doses based on thyroid gland weight (gram), clinical findings, and 3-hour radioiodine uptake (3-hr RAIU).

Material And Method: A retrospective study was performed of 305 hyperthyroid patients who received initial I-131 therapy at the Nuclear Medicine Department of Rajavithi Hospital, Bangkok between January 2010 and December 2014. Read More

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February 2017
4 Reads

Results of Lower Abdominal Ultrasound as Part of Whole Abdominal Ultrasound in Patients with and without Indications Related to Lower Abdomen.

J Med Assoc Thai 2017 Feb;100 Suppl 1:S177-82

Background: Whole abdominal ultrasound sometimes shows no significant findings in the lower abdomen, especially in patients without indications related to this area. Those patients have to spend a lot of time waiting for their test and refrain from urination in order to complete whole abdominal examinations but gain no additional benefit.

Objective: To analyze the results of lower abdominal ultrasound in patients who were sent for ultrasound of the whole abdomen; to correlate the results with indications for requesting ultrasound based on diagnosis or clinical findings in the lower abdomen; and examine their associations with further management of the patients who had positive findings. Read More

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February 2017
5 Reads

Immunohistochemistry of Cytokeratin 7, Cytokeratin 20 and Thyroid Transcription Factor-1 in Metastatic Carcinoma of Cervical Lymph Node Biopsy for Identification of Pulmonary Origin in Rajavithi Hospital.

J Med Assoc Thai 2017 Feb;100 Suppl 1:S172-6

Background: One of the most powerful tools used in “the team approach in modern medicine” is immunohistochemistry, a minimally invasive investigative technique which is helpful in many respects, such as in suggesting or defining the primary site of metastatic malignant neoplasms. The panel of Cytokeratin7 (CK7), Cytokeratin20 (CK20) and Thyroid Transcription Factor-1 (TTF-1) is one of the most frequently used, and this study examined expressions of this panel in Rajavithi Hospital in order to assess their significance.

Objective: To study the expression of CK7, CK20 and TTF-1 in metastatic carcinoma in neck node biopsy found in the Rajavithi Hospital database, and to assess their effectiveness in identifying pulmonary origin. Read More

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February 2017
5 Reads

Correlation of 25-Hydroxyvitamin D Levels in Serum vs. Breastmilk in Vitamin D-Supplementation Breastfeeding Women during Lactation: Randomized Double Blinded Control Trial.

J Med Assoc Thai 2017 Feb;100 Suppl 1:S165-71

Background: Vitamin D deficiency in pregnancy and lactation increases the risk of adverse perinatal outcomes; however, although Vitamin D supplementation during pregnancy and lactation is recommended, suggested dose ranges vary.

Objective: To determine whether vitamin D31,800 IU/d supplementation in lactating mothers improves their vitamin D status and breast-feeding milk.

Material And Method: This was a randomized, placebo–controlled study of Thai pregnant women in their third trimester. Read More

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February 2017
1 Read

Outcome of Latissimus Dorsi Flap Chest Wall Reconstruction In Rajavithi Hospital.

J Med Assoc Thai 2017 Feb;100 Suppl 1:S157-64

Background: Latissimus Dorsi flap (LD flap) has been used since the eighteenth century to cover large chest wall defects after total mastectomy and is thought to be superior to split thickness skin graft in terms of both cosmetic results and functionality. The outcomes and complications resulting from the use of LD flap reconstruction for large breast cancer are not well documented in Thailand.

Objective: To describe a technique using the Latissimus Dorsi musculocutaneous flap for breast reconstruction. Read More

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February 2017
1 Read

Role of Hypercoagulable State for Predictive Ovarian Malignancy in Women with a Pelvic Mass.

Authors:
Marut Yanaranop

J Med Assoc Thai 2017 Feb;100 Suppl 1:S148-56

Background: Ovarian cancer (OC) is an important malignancy in women worldwide and is associated with hypercoagulable state and high risk of venous thromboembolism (VTE).

Objective: To assess the performance of preoperative blood coagulability in discriminating between OCs and benign gynecologic diseases in women presenting with a pelvic mass, and to study the incidence of postoperative thromboembolic events.

Material And Method: Preoperative coagulation tests (platelet count, prothrombin time, activated partial thromboplastin time, thrombin time, fibrinogen and D-dimer levels), and serum cancer antigen 125 (CA125) were investigated in women over 18 years old with clinically diagnosed pelvic or adnexal mass who underwent elective surgery at Rajavithi Hospital between January 2012 and December 2013. Read More

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February 2017
2 Reads

Diabetic Retinopathy: Current Treatment and Thailand Perspective.

J Med Assoc Thai 2017 Feb;100 Suppl 1:S136-47

Diabetes mellitus is a common and chronic metabolic disorder involving multiple organ systems. Major eye involvements include diabetic macular edema (DME) and proliferative diabetic retinopathy (PDR). With a significantly increasing global number of cases of diabetes and the tendency towards an aging population, sight-threatening diabetic retinopathies are expected to increase from 37. Read More

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February 2017
5 Reads

Preferred Route of Delivery of Thai Pregnant Women.

J Med Assoc Thai 2017 Feb;100 Suppl 1:S131-5

Background: Pregnant women who prefer cesarean delivery may request it without any obstetric indication, and this could be one of the reasons for the high rates of cesarean deliveries.

Objective: To determine the route of delivery preferred by Thai pregnant women.

Material And Method: A cross-sectional study was performed of Thai pregnant women who attended the antenatal care (ANC) clinic in Rajavithi Hospital between February 1, 2011 and July 31, 2011. Read More

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February 2017
1 Read

Prevalence of Chronic Hepatitis B Infection in Patients with Systemic Lupus Erythematosus: Viral Reactivation and Impact on Disease Activity.

J Med Assoc Thai 2017 Feb;100 Suppl 1:S124-30

Background: Hepatitis B virus (HBV) infection is prevalent in many parts of the world, especially in South East Asia, and reactivation of HBV can occur after patients receive immunosuppressive agents. Systemic Lupus Erythematosus (SLE) is one of the most important autoimmune diseases because of its high morbidity and mortality rates. Most SLE patients need corticosteroid and immunosuppressive drugs as a treatment regimen; however, there are conflicting recommendations for screening for HBsAg in patients undergoing immunosuppressive therapy and diverse theories about the impact of chronic HBV infection on clinical manifestations of SLE and its activity. Read More

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February 2017
1 Read

Comparison of Surgical Results of Direct Vertebral Rotation with those of Simple Rod Derotation for Correction of Adolescent Idiopathic Scoliosis.

J Med Assoc Thai 2017 Feb;100 Suppl 1:S116-23

Background: Adolescent idiopathic scoliosis (AIS) is abnormal spinal alignment in 3 planes: the coronal, sagittal and rotational planes, and one of the methods used for its treatment is surgical correction. In the present day, the most common surgical techniques used to correct spinal alignment are simple rod derotation and direct vertebral derotation.

Objective: To compare spinal alignment results after surgical correction with simple rod derotation and direct vertebral derotation. Read More

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February 2017
1 Read

Clinical Characteristics, Treatment Outcomes and Risk Assessment of Patients with Acute Upper Gastrointestinal Bleeding in Rajavithi Hospital, Thailand.

J Med Assoc Thai 2017 Feb;100 Suppl 1:S104-15

Background: Acute upper gastrointestinal bleeding (UGIB) is common and carries significant morbidity worldwide. Effective risk assessment for UGIB is required in order to deliver the optimal therapeutic plans.

Objectives: To describe clinical characteristics and treatment outcomes of acute UGIB in Thailand and to evaluate predictors for rebleeding and complications. Read More

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February 2017
1 Read