3,214 results match your criteria Journal of the Mechanical Behavior of Biomedical Materials [Journal]


Resin adjustment of three-dimensional printed thermoset occlusal splints: Bonding properties - Short communication.

J Mech Behav Biomed Mater 2019 Apr 17;95:215-219. Epub 2019 Apr 17.

Department of Biomaterials Science and Turku Clinical Biomaterials Centre - TCBC, Institute of Dentistry, University of Turku and City of Turku Welfare Division, Oral Health Care, Finland, Lemminkäisenkatu 2, Turku, FI-20520, Finland.

Objectives: To evaluate the interfacial adhesion of an autopolymerizing acrylic resin to 3D printed thermoset occlusal splints compared to thermoplastic occlusal splints.

Materials And Methods: Cylinders made of an autopolymerizing acrylic resin were adhered to 3D printed thermoset and also to thermoplastic plates. A different surface treatment and three storage conditions were used: dry, 7 days water-storage and 14 days water-storage. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.04.011DOI Listing

The dehydration effect on mechanical properties of tooth enamel.

J Mech Behav Biomed Mater 2019 Apr 17;95:210-214. Epub 2019 Apr 17.

Tribology Research Institute, School of Mechanical Engineering, Southwest Jiaotong University, Chengdu, 610031, Sichuan, China.

Exploring the subtle mechanical property changes of tooth enamel in different conditions is important for dental research. However, some experimental results can be deceptive and may lead to misunderstanding. In particular, we show the dehydration associated with increased mechanical properties of tooth enamel as monitored by Nanomechanical System Testing (NST) can be misleading. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17516161183173
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http://dx.doi.org/10.1016/j.jmbbm.2019.04.013DOI Listing
April 2019
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Preliminary results of the tribological performance of new modular temporary knee spacer antibiotic-impregnated.

J Mech Behav Biomed Mater 2019 Apr 17;95:205-209. Epub 2019 Apr 17.

G21 S.r.l., San Possidonio, Modena, Italy.

Purpose: Although total knee arthroplasty is one of the most successful and consolidated surgical procedure, the infection rate is still elevate. To treat infected knee arthroplasties, in the past years was approached a procedure that involved the implantation of an antibiotic-loaded temporary spacer. This spacer helps maintain an appropriate soft tissue envelope and the patients are able to walk during the interim period. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17516161193039
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http://dx.doi.org/10.1016/j.jmbbm.2019.04.009DOI Listing
April 2019
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Mechanical and tribological assessment of silica nanoparticle-alginate-polyacrylamide nanocomposite hydrogels as a cartilage replacement.

J Mech Behav Biomed Mater 2019 Apr 17;95:196-204. Epub 2019 Apr 17.

Department of Mechanical Engineering, Auckland University of Technology, Auckland, 1010, New Zealand.

Interpenetrating polymer network (IPN) of alginate-polyacrylamide (ALG-PAAm) has been explored in the past, showing a potential capacity as a structural biomaterial to replace cartilage lesions. In the current study, silica nanoparticles (Si-NPs) were introduced to ALG-PAAm IPN hydrogel as a reinforcement and the mechanical and tribological characteristics of the resultant nanocomposite hydrogel was investigated. Mechanical tests were performed including indentation, unconfined uniaxial compression and stress relaxation to explore the effect of Si-NP concentration on elastic and viscoelastic responses, while friction and wear studies were conducted with the hydrated samples sliding against an alumina ceramic ball. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.04.020DOI Listing

Deformation behavior of porous PHBV scaffold in compression: A finite element analysis study.

J Mech Behav Biomed Mater 2019 Apr 17;96:1-8. Epub 2019 Apr 17.

School of Mechanical and Mining Engineering, The University of Queensland, QLD, 4072, Australia.

Macroscopic mechanical properties of porous PHBV bone TE scaffolds have been well studied. However, their mechanical behavior at microscopic level has yet to be explored. In this study, the micro-mechanical behavior of a PHBV bone scaffold under compression was investigated using a numerical method that combines micro-computed tomography (μ-CT) and finite element analysis (FEA). Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.04.030DOI Listing

Mechanical modeling of pimple growth.

J Mech Behav Biomed Mater 2019 Apr 16;95:191-195. Epub 2019 Apr 16.

Advanced Materials for Energy and Environment, Department of Earth and Environmental Engineering, Columbia University, New York, NY, 10027, USA; School of Chemical Engineering, Northwest University, Xi'an, 710069, PR China.

Pimple is one of the most common skin diseases for humans, whose growth cause pain yet the corresponding mechanical analysis is lacking. A finite element model is developed to quantify the deformation field with the expansion of follicle, and then the mechanical stimulus is related to the sensation of pain during the development of pimple. Parametric studies show the dependence of mechanical stimulus and pain level on the pimple-surrounded structures, follicle depth and mechanical properties of the epidermis. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.04.017DOI Listing

The mechanical behavior of brain surrogates manufactured from silicone elastomers.

J Mech Behav Biomed Mater 2019 Apr 16;95:180-190. Epub 2019 Apr 16.

Department of Mechanical Engineering, Iowa State University of Science and Technology, 2529 Union Drive, Ames, IA, 50011, USA. Electronic address:

The ongoing conflict against terrorism has resulted in an escalation of blast-induced traumatic brain injuries (bTBI) caused by improvised explosive devices (IEDs). The destructive IEDs create a blast wave that travels through the atmosphere. Blast-induced traumatic brain injuries, attributed to the blast wave, can cause life-threatening injuries and fatalities. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17516161183167
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http://dx.doi.org/10.1016/j.jmbbm.2019.04.005DOI Listing
April 2019
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Newer vs. older CAD/CAM burs: Influence of bur experience on the fatigue behavior of adhesively cemented simplified lithium-disilicate glass-ceramic restorations.

J Mech Behav Biomed Mater 2019 Apr 9;95:172-179. Epub 2019 Apr 9.

Department of Dental Materials and Prosthodontics, São Paulo State University (Unesp) - Institute of Science and Technology, São José dos Campos, Brazil. Electronic address:

This study evaluated the effect of the CAD/CAM burs experience (newer vs older as consequence of the milling sequence) on fatigue failure load (FFL), number of cycles for failure (CFF), and survival rates of lithium disilicate glass-ceramic simplified restorations adhesively cemented to a dentin analogue substrate. Three sets of CAD/CAM burs were used to mill disc-shaped ceramic specimens (1 bur set - 18 milled discs with 10 mm diameter and 1.5 mm thickness), considering the bur experience as a result of the milling sequence to compose the study groups: G1-6 - discs obtained from the 1st to 6th milling of each bur set; G7-12 - specimens from the 7th to 12th milling; G13-18 - discs from the 13th to 18th. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17516161193025
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http://dx.doi.org/10.1016/j.jmbbm.2019.04.002DOI Listing
April 2019
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Load-bearing capacities of ultra-thin occlusal veneers bonded to dentin.

J Mech Behav Biomed Mater 2019 Apr 13;95:165-171. Epub 2019 Apr 13.

Clinic of Fixed and Removable Prosthodontics and Dental Material Science, Center of Dental Medicine, University of Zurich, Switzerland. Electronic address:

Objectives: To test whether the load-bearing capacity of occlusal veneers made of ceramic or hybrid materials bonded to dentin does differ from those of porcelain-fused-to metal or lithium disilicate glass ceramic crowns.

Material And Methods: In 80 human molars, occlusal tooth substance was removed so that the defects extended into dentin, simulating defects caused by attrition/erosion. Restorations at a standardized thickness of either 0. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17516161193001
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http://dx.doi.org/10.1016/j.jmbbm.2019.04.006DOI Listing
April 2019
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The investigation of fluid flow in cartilage contact gap.

J Mech Behav Biomed Mater 2019 Apr 13;95:153-164. Epub 2019 Apr 13.

Department of Infrastructure Engineering, The University of Melbourne, Victoria, 3010, Australia. Electronic address:

Synovial fluid flow in articular joint capsule plays an important role during mixed mode lubrication. However, the actual fluid flow behaviour during cartilage contact has not been fully understood so far. This is due to the difficulties in measuring the gap permeability using conventional experimental techniques. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17516161183178
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http://dx.doi.org/10.1016/j.jmbbm.2019.04.008DOI Listing
April 2019
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Exposure effects of endotoxin-free titanium-based wear particles to human osteoblasts.

J Mech Behav Biomed Mater 2019 Apr 10;95:143-152. Epub 2019 Apr 10.

Department of Physics, UNESP, São Paulo State University, 17033-360, Bauru, SP, Brazil.

Titanium-based materials are widely employed by the biomedical industry in orthopedic and dental implants. However, when placed into the human body, these materials are highly susceptible to degradation processes, such as corrosion, wear, and tribocorrosion. As a consequence, metallic ions or particles (debris) may be released, and although several studies have been conducted in recent years to better understand the effects of their exposure to living cells, a consensual opinion has not yet been obtained. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17516161193028
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http://dx.doi.org/10.1016/j.jmbbm.2019.04.003DOI Listing
April 2019
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Effect of fluorine substitution on sintering behaviour, mechanical and bioactivity of hydroxyapatite.

J Mech Behav Biomed Mater 2019 Apr 9;95:136-142. Epub 2019 Apr 9.

Bioceramics and Coating Division, CSIR-Central Glass & Ceramic Research Institute, 196 Raja S.C. Mullick Road, Kolkata 700032, India. Electronic address:

Fluorine substituted hydroxyapatite (FAp) with different degree of fluorine (F) substitution, has been synthesized using hydrothermal synthesis method. In the present work, as synthesized powders were consolidated by sintering at 1200 °C in air for 1 h. The sintered specimens were characterized using Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) for phase analysis. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17516161193024
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http://dx.doi.org/10.1016/j.jmbbm.2019.03.032DOI Listing
April 2019
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Constrained mixture modeling affects material parameter identification from planar biaxial tests.

J Mech Behav Biomed Mater 2019 Apr 8;95:124-135. Epub 2019 Apr 8.

Biomechanics Section, Mechanical Engineering Department, KU Leuven, Leuven, Belgium.

The constrained mixture theory is an elegant way to incorporate the phenomenon of residual stresses in patient-specific finite element models of arteries. This theory assumes an in vivo reference geometry, obtained from medical imaging, and constituent-specific deposition stretches in the assumed reference state. It allows to model residual stresses and prestretches in arteries without the need for a stress-free reference configuration, most often unknown in patient-specific modeling. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17516161193001
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http://dx.doi.org/10.1016/j.jmbbm.2019.03.029DOI Listing
April 2019
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Design of a bio-inspired composite using probabilistic fracture mechanics.

J Mech Behav Biomed Mater 2019 Apr 7;95:96-102. Epub 2019 Apr 7.

Department of Aerospace Engineering, Indian Institute of Space Science and Technology, Thiruvananthapuram, Kerala, India.

Artificial composites inspired from biological materials such as nacre and bone has a staggered structure of hard inclusions surrounded by a soft interface. These composites possess an excellent combination of strength, toughness and stiffness. These properties depends on a critical value of overlap ratio of inclusions, and hence is one of major parameters in the design of bio-inspired composites. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.04.001DOI Listing
April 2019
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A combined experimental-numerical lamellar-scale approach of tensile rupture in arterial medial tissue using X-ray tomography.

J Mech Behav Biomed Mater 2019 Apr 1;95:116-123. Epub 2019 Apr 1.

Mines Saint-Etienne, Univ Lyon, Univ Jean Monnet, INSERM, U 1059 Sainbiose, Centre CIS, F-42023, Saint-Etienne, France.

Aortic dissection represents a serious cardio-vascular disease and life-threatening event. Dissection is a sudden delamination event of the wall, possibly leading to rupture within a few hours. Current knowledge and practical criteria to understand and predict this phenomenon lack reliable models and experimental observations of rupture at the lamellar scale. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.03.028DOI Listing
April 2019
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Comparison of cell mechanical measurements provided by Atomic Force Microscopy (AFM) and Micropipette Aspiration (MPA).

J Mech Behav Biomed Mater 2019 Apr 8;95:103-115. Epub 2019 Apr 8.

Centro de Tecnología Biomédica, Universidad Politécnica de Madrid, 28223, Pozuelo de Alarcón, Madrid, Spain; Departamento de Ciencia de Materiales, ETSI Caminos, Canales y Puertos, Universidad Politécnica de Madrid, 28040, Madrid, Spain; CIBER-BBN, Biomedical Research Networking Center in Bioengineering Biomaterials and Nanomedicine, Spain.

A comparative analysis of T-lymphocyte mechanical data obtained from Micropipette Aspiration (MPA) and Atomic Force Microscopy (AFM) is presented. Results obtained by fitting the experimental data to simple Hertz and Theret models led to non-Gaussian distributions and significantly different values of the elastic moduli obtained by both techniques. The use of more refined models, taking into account the finite size of cells (simplified double contact and Zhou models) reduces the differences in the values calculated for the elastic moduli. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.03.031DOI Listing

In situ measurement of dental resin-based composite volumetric shrinkage and temperature effects using in-fibre bragg grating methods.

J Mech Behav Biomed Mater 2019 Mar 29;95:89-95. Epub 2019 Mar 29.

Department of Mechanical Engineering, Faculty of Engineering, University of Alberta, Edmonton, Alberta, Canada. Electronic address:

Objectives: Resin-based composites (RBCs) are commonly used in dental restorations. It is known that RBCs undergo volumetric shrinkage during photo-polymerization leading to a detrimental increased stress state at the RBC-tooth interface and potentially early restoration failure. The objectives of this in vitro study were: (1) to ascertain whether shrinkage strain could be measured using in-fibre Bragg grating (FBG) technology, without confounding effects of temperature; and (2) to ascertain whether FBGs can detect alteration in shrinkage strain with introduction of a surface condition change at the RBC-cavity analog interface. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.03.026DOI Listing
March 2019
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Influence of MgO nanoparticles on the mechanical properties of coated hydroxyapatite nanocomposite scaffolds produced via space holder technique: Fabrication, characterization and simulation.

J Mech Behav Biomed Mater 2019 Mar 22;95:76-88. Epub 2019 Mar 22.

Mechanical Engineering Department, Amirkabir University of Technology, Tehran 15875-4413, Iran.

In the current study, hydroxyapatite (HA)-MgO scaffolds are fabricated with the aid of the space holder technique using NaCl as the spacer type. After that, the fabricated samples are deposited in gelatin (GN) with ibuprofen (IBO) substitution to create GN-IBO thin surface coating. The samples are then synthesized chemically and the associated properties are studied using X-ray diffraction (XRD) and scan electron microscopy (SEM) equipped with the energy dispersive spectroscopy (EDS). Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.03.014DOI Listing
March 2019
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MMP-9 selectively cleaves non-D-banded material on collagen fibrils with discrete plasticity damage in mechanically-overloaded tendon.

J Mech Behav Biomed Mater 2019 Mar 22;95:67-75. Epub 2019 Mar 22.

School of Biomedical Engineering, Dalhousie University, 5981 University Avenue, Halifax, NS, Canada B3H 4R2; Department of Applied Oral Sciences, Dalhousie University, 5981 University Avenue, Halifax, NS, Canada B3H 4R2. Electronic address:

The mechanical properties of tendon are due to the properties and arrangement of its collagen fibril content. Collagen fibrils are highly-organized supermolecular structures with a periodic banding pattern (D-band) indicative of the geometry of molecular organization. Following mechanical overload of whole tendon, collagen fibrils may plastically deform at discrete sites along their length, forming kinks, and acquiring a fuzzy, non-D-banded, outer layer (shell). Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.03.020DOI Listing
March 2019
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Effect of strain rate on transient local strain variations in articular cartilage.

J Mech Behav Biomed Mater 2019 Mar 22;95:60-66. Epub 2019 Mar 22.

Human Performance Laboratory, Faculty of Kinesiology, The University of Calgary, 2500 University Drive NW, Calgary, Canada, T2N 1N4. Electronic address:

The non-homogeneous, anisotropic material properties, and triphasic nature of articular cartilage enables diarthrodial joints to withstand large and complex physiological loading conditions. To develop biomaterials that provide similar functional properties as those found in articular cartilage, it is vital to have knowledge of the strain distributions in cartilage for a large range of loading conditions. Applied stress vs. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.03.022DOI Listing
March 2019
2 Reads

Evaluation of mechanical properties and shrinkage stress of thiol-ene-methacrylate dental composites with synthesized fluorinated allyl ether.

J Mech Behav Biomed Mater 2019 Mar 29;95:53-59. Epub 2019 Mar 29.

College of Materials Science and Engineering, South China University of Technology, Guangzhou, 510641, Guangdong, China. Electronic address:

It has already been reported that incorporation of thiol-ene into methacrylate resin could reduce shrinkage stress significantly. However, the mass fraction of thiol-ene in thiol-ene-methacrylate resin system should be limited because of deterioration of mechanical properties. In order to increase mass fraction of thiol-ene in thiol-ene-methacrylate ternary resin system, a new fluorinated ally ether (FUAE) was synthesized and mixed with pentaerythritol tetra (3-mercaptopropionate) (PETMA) at molar ratio of 1:1 to form new thiol-ene resin system, and then the thiol-ene resin was incorporated into Bis-GMA/TEGDMA resin to prepare thiol-ene-methacrylate resin system. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.03.027DOI Listing

The development of an artificial skin model and its frictional interaction with wound dressings.

J Mech Behav Biomed Mater 2019 Jun 16;94:308-316. Epub 2019 Mar 16.

Laboratory for Advanced Lubricating Materials, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai 201210, China. Electronic address:

Human skin interacts with various materials in our daily life. The interaction between human skin and contacting materials is very important for the development of skin contacting products. Owing to the ethic and different testing results because of the using of in vivo or ex vivo skin, it is important to develop an artificial skin model (ASM) for the study. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.03.013DOI Listing
June 2019
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Multi-laminate annulus fibrosus repair scaffold with an interlamellar matrix enhances impact resistance, prevents herniation and assists in restoring spinal kinematics.

J Mech Behav Biomed Mater 2019 Apr 1;95:41-52. Epub 2019 Apr 1.

The Laboratory of Orthopaedic Tissue Regeneration & Orthobiologics, Department of Bioengineering, Clemson University, Clemson, SC, USA. Electronic address:

Focal defects in the annulus fibrosus (AF) of the intervertebral disc (IVD) arising from herniation have detrimental impacts on the IVD's mechanical function. Thus, biomimetic-based repair strategies must restore the mechanical integrity of the AF to help support and restore native spinal loading and motion. Accordingly, an annulus fibrosus repair patch (AFRP); a collagen-based multi-laminate scaffold with an angle-ply architecture has been previously developed, which demonstrates similar mechanical properties to native outer AF (oAF). Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.03.030DOI Listing

Understanding static and dynamic bending size-dependencies in the design of a nanofibrous scaffold.

J Mech Behav Biomed Mater 2019 Mar 21;95:34-40. Epub 2019 Mar 21.

Integrated Chinese & Western Medicine Oncology Research Center, Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi 330004, China. Electronic address:

From a series of experimental measurements and supplemented by results from a computational model, we investigated the static and dynamic size dependent behaviors of a single-strand polycaprolactone (PCL) nanofiber. For the static bending, the fiber stiffness showed a dramatic increase as the fiber diameter is reduced and for the dynamic bending, the resonant frequency exhibited a very similar trend. Employing the strain gradient (SG) theory, we formulated a model that not only accurately captures the magnitude of the experimentally observed size dependent response but it is also, able to correctly predict the onset of the inverse square behavior. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.03.021DOI Listing

Shape-fitting collagen-PLA composite promotes osteogenic differentiation of porcine adipose stem cells.

J Mech Behav Biomed Mater 2019 Mar 22;95:21-33. Epub 2019 Mar 22.

Dept. of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA; Dept. of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. Electronic address:

Craniomaxillofacial bone defects can occur as a result of congenital, post-oncologic, and high-energy impact conditions. The scale and irregularity of such defects motivate new biomaterials to promote regeneration of the damaged bone. We have recently described a mineralized collagen scaffold capable of instructing stem cell osteogenic differentiation and new bone infill in the absence of traditional osteogenic supplements. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.03.017DOI Listing
March 2019
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Towards intervertebral disc engineering: Bio-mimetics of form and function of the annulus fibrosus lamellae.

J Mech Behav Biomed Mater 2019 Jun 22;94:298-307. Epub 2019 Mar 22.

The Fleischman Faculty of Engineering, Tel Aviv University, Tel Aviv 69978, Israel.

The aging western society is heavily afflicted with intervertebral disc (IVD) degeneration. Replacement or repair of the degenerated IVD with an artificial bio-mimetic construct is one of the challenges of future research due to its complex structure and unique biomechanical function. Herein, biocomposite laminates made of long collagen fibers in unidirectional (-1. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.03.023DOI Listing

Biomechanical test protocols to detect minor injury effects in intervertebral discs.

J Mech Behav Biomed Mater 2019 Mar 29;95:13-20. Epub 2019 Mar 29.

Leni & Peter W. May Department of Orthopaedics, Icahn School of Medicine at Mount Sinai, One Gustave Levy Place, Box 1188, New York, NY, 10029-6574, USA. Electronic address:

Intervertebral discs (IVDs) maintain flexibility of the spine and bear mechanical load. Annulus fibrosus (AF) defects are associated with IVD degeneration and herniation which disrupt biomechanical function and can cause pain. AF puncture injuries can induce IVD degeneration but are needed to inject therapies. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.03.024DOI Listing
March 2019
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Extra low interstitial titanium based fully porous morphological bone scaffolds manufactured using selective laser melting.

J Mech Behav Biomed Mater 2019 Mar 28;95:1-12. Epub 2019 Mar 28.

School of Engineering, Faculty of Science and Engineering, University of Wolverhampton, Telford Campus, Telford, TF2 9NT, United Kingdom.

Lattice structure based morphologically matched scaffolds is rapidly growing facilitated by developments in Additive Manufacturing. These porous structures are particularly promising due to their potential in reducing stress shielding and maladapted stress concentration. Accordingly, this study presents Extra Low Interstitial (ELI) Titanium alloy based morphological scaffolds featuring three different porous architecture. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.03.025DOI Listing
March 2019
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Biomechanical response of a novel intervertebral disc prosthesis using functionally graded polymers: A finite element study.

J Mech Behav Biomed Mater 2019 Jun 20;94:288-297. Epub 2019 Feb 20.

Ramsay Générale de Santé, Hôpital privé Le Bois, 59000 Lille, France.

With their gradual and continuous properties, functionally graded polymers (FGP) have high potentials to reproduce the regional variation in microstructure/property of the natural intervertebral disc and, therefore, the functional anatomy and biomechanics of the soft tissue. This paper evaluates by finite element analysis the biomechanical response and stress distribution of a novel disc prosthesis using FGP. The kinetics of the FGP parameters is designed using experimental data issued from linear ethylene copolymers over a wide crystallinity range. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.02.021DOI Listing

Functional gradient structural design of customized diabetic insoles.

J Mech Behav Biomed Mater 2019 Jun 6;94:279-287. Epub 2019 Mar 6.

John Scale Centre for Biomedical Engineering, University College London, Royal National Orthopaedic Hospital, Stanmore HA7 4LP, UK.

Diabetic foot is a common and serious complication of diabetes, largely due to sensory neuropathy and excessive mechanical stresses. Studies have shown that reducing the contact pressure can effectively lower the incidence of diabetic foot. A new design method is proposed in this study for optimizing the stress distribution of the contact surfaces between the foot and the insole by applying functional gradient structural properties to the insole. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17516161183174
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http://dx.doi.org/10.1016/j.jmbbm.2019.03.003DOI Listing
June 2019
6 Reads

Torsional whole-life transformation ratchetting under pure-torsional and non-proportional multiaxial cyclic loadings of NiTi SMA at human-body temperature: Experimental observations and life-prediction model.

J Mech Behav Biomed Mater 2019 Jun 14;94:267-278. Epub 2019 Mar 14.

Department of Civil Engineering, University of Siegen, Siegen 57068, Germany.

Torsional whole-life transformation ratchetting is investigated under pure-torsional and non-proportional multiaxial loadings of NiTi SMA micro-tubes at human-body temperature (310 K), where three paths of torsional loadings and five paths of multiaxial ones are considered. It is observed that the evolution of the torsional whole-life transformation ratchetting depends strongly on the loading paths and stress levels, and the fatigue lives of pure-torsional loadings decrease faster than that of uniaxial and multiaxial ones with the increase of peak stress. Based on the experimental investigations, a life-prediction model which depends on the applied stress levels is proposed for NiTi SMA micro-tubes, where the martensite transformation and reorientation of NiTi SMAs are considered. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.03.010DOI Listing
June 2019
1 Read

Effect of cell sample size in atomic force microscopy nanoindentation.

J Mech Behav Biomed Mater 2019 Jun 18;94:259-266. Epub 2019 Mar 18.

Insigneo Institute for in silico Medicine, University of Sheffield, Mappin Street, Sheffield S1 3JD, UK; Department of Mechanical Engineering, University of Sheffield, Western Bank, Sheffield S10 2TN, UK. Electronic address:

Single-cell technologies are powerful tools to evaluate cell characteristics. In particular, Atomic Force Microscopy (AFM) nanoindentation experiments have been widely used to study single cell mechanical properties. One important aspect related to single cell techniques is the need for sufficient statistical power to obtain reliable results. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.03.018DOI Listing
June 2019
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Periprosthetic biomechanical response towards dental implants, with functional gradation, for single/multiple dental loss.

J Mech Behav Biomed Mater 2019 Jun 2;94:249-258. Epub 2019 Mar 2.

Materials Research Centre, Indian Institute of Science, Bengaluru 560012, Karnataka, India; Translational Center on Biomaterials for Orthopaedic and Dental Applications, Indian Institute of Science, Bengaluru 560012, Karnataka, India; Centre for BioSystems and Engineering, Indian Institute of Science, Bengaluru 560012, Karnataka, India. Electronic address:

The differences in shape and stiffness of the dental implants with respect to the natural teeth (especially, dental roots) cause a significant alteration of the periprosthetic biomechanical response, which typically leads to bone resorption and ultimately implant loosening. In order to avoid such clinical complications, the implant stiffness needs to be appropriately adapted. In this study, hollow channels were virtually introduced within the designed implant screws for reduction of the overall stiffness of the prototype. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.03.001DOI Listing

Dry-bonding to dentin using alternative conditioners based on iron-containing solutions or nitric acid.

J Mech Behav Biomed Mater 2019 Jun 20;94:238-248. Epub 2019 Mar 20.

Department of Restorative Dentistry, Operative Dentistry Division, Piracicaba Dental School, University of Campinas, Avenida Limeira 901, Bairro Areião, 13414-903 Piracicaba, SP, Brazil. Electronic address:

Objectives: To evaluate the effect of experimental conditioners (10-3 solution - 10-3, 6.8% ferric oxalate - FOX, and 1.4% nitric acid - NI) on dentin elastic modulus, flexural strength, bond strength, failure mode, and adhesive interface morphology of two etch-and-rinse adhesives (XP Bond, Dentsply or One-Step, Bisco) applied on etched dry dentin. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.03.015DOI Listing

Voxel-based micro-finite element analysis of dental implants in a human cadaveric mandible: Tissue modulus assignment and sensitivity analyses.

J Mech Behav Biomed Mater 2019 Jun 13;94:229-237. Epub 2019 Mar 13.

Department of Mechanical Engineering, Penn State University, University Park, PA, United States. Electronic address:

The success of dental implant treatment is related to the complex 3-dimensional (3D) biomechanics of the implant-bone interaction. In this work, 3D numerical models are built based on micro X-ray computed tomography (micro-CT) images of a cadaveric mandible specimen with implants placed in it. The simulation results show that the computed strain values in bone are sensitive to the uncertainties in trabecular tissue modulus and fairly insensitive to the modulus of implants and teeth and the detailed geometry of the fixed boundary condition. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.03.008DOI Listing

Preparation of low shrinkage stress dental composite with synthesized dimethacrylate oligomers.

J Mech Behav Biomed Mater 2019 Jun 18;94:222-228. Epub 2019 Mar 18.

School of Materials Science and Engineering, South China University of Technology, 381 Wushan Road, Tianhe District, Guangzhou 510641, China; Key lab of Guangdong Province for High Property and Functional Macromolecular Materials, South China University of Technology, Gunagzhou 510641, China. Electronic address:

Two dimethacrylate oligomers named polypropylenglycol bis(2-hydroxy-3-methoxypropyl) dimethacrylates (380PPMA and 640PPMA) with different molecular weight were synthesized through ring opening addition reaction between epoxy terminated oligomers PPDE and methacrylic acid, and their structures were confirmed by FT-IR and H-NMR spectra. The PPMAs were used to replace TEGDMA partially in Bis-GMA/TEGDMA (50/50, wt./wt. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.03.016DOI Listing
June 2019
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Structural and mechanical characteristics of collagen tissue coated with chitosan in a liquid CO/water system at different pressures.

J Mech Behav Biomed Mater 2019 Jun 16;94:213-221. Epub 2019 Mar 16.

Bakulev Scientific Center for Cardiovascular Surgery, 135 Rublevskoe Sh., Moscow 121552, Russian Federation.

Chitosan coatings of biological heart-valve prostheses enhance their biocompatibility, resistance to pathogenic microflora and lifetime. Collagen tissues can be coated with chitosan in aqueous solution acidified, to make chitosan soluble, with HCO formed from a coexisting liquid CO phase under pressure. The advantage of HCO is that it can be easily removed after the coating procedure. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.03.012DOI Listing

Effect of different loading pistons on stress distribution of a CAD/CAM silica-based ceramic: CAD-FEA modeling and fatigue survival analysis.

J Mech Behav Biomed Mater 2019 Jun 15;94:207-212. Epub 2019 Mar 15.

Federal University of Rio Grande do Norte (UFRN), Department of Dentistry, Division of Prosthodontics, Natal, Rio Grande do Norte, Brazil. Electronic address:

Purpose: This study evaluated the effect of different loading pistons, made of various materials and with different elastic moduli acting as antagonist material, on stress distribution and fatigue behavior of a CAD/CAM silica-based ceramic.

Materials And Methods: Discs of CAD/CAM made silica-based ceramic (N = 60) (VITA MARK II) were divided into six groups (n = 10 per group), according to the test method (M: Monotonic; F: Fatigue) and the antagonist piston material (T: Tungsten; S: Steel; G: Epoxy resin). FT, FS and FG combinations were submitted to mechanical cycling (2 × 10 cycles, 4 Hz, 45 N). Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.03.011DOI Listing
June 2019
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The effect of combined loading cycles on the wear of reverse shoulder joint replacements.

J Mech Behav Biomed Mater 2019 Jun 26;94:201-206. Epub 2019 Feb 26.

Bioengineering Group, School of Engineering, Newcastle University, Newcastle upon Tyne NE1 7RU, England, UK.

Wear of polyethylene is a current limitation in the long-term survival of reverse shoulder arthroplasties (RSAs). The purpose of this study was to investigate, for the first time, the influence of a combination of clinically relevant activities of daily living (ADLs) as patterns of motion and loading on the wear of ultra-high molecular-weight polyethylene (UHMWPE) in RSA. This physiological combined cycle, termed "repeated-motion-load", was applied on four new samples of a commercially available reverse shoulder prosthesis for five million cycles using the unique Newcastle Shoulder Wear Simulator. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17516161193011
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http://dx.doi.org/10.1016/j.jmbbm.2019.02.027DOI Listing
June 2019
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Tribological behavior of bioactive multi-material structures targeting orthopedic applications.

J Mech Behav Biomed Mater 2019 Jun 1;94:193-200. Epub 2019 Mar 1.

Center for Micro-Electro Mechanical Systems (CMEMS-UMinho), University of Minho, Campus de Azurém, 4800-058 Guimarães, Portugal.

The following study proposes a multi-material solution in which Ti6Al4V cellular structures produced by Selective Laser Melting are impregnated with bioactive materials (hydroxyapatite or β-tricalcium phosphate) using press and sintering technique. To assess the tribological response of these structures, an alumina plate was used as a counterpart in a flat-on-flat reciprocating sliding test. Ti6Al4V cellular structures impregnated with bioactive materials displayed the highest wear resistance when compared with the unreinforced structures. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.02.028DOI Listing

Regional dependency of bovine meniscus biomechanics on the internal structure and glycosaminoglycan content.

J Mech Behav Biomed Mater 2019 Jun 21;94:186-192. Epub 2019 Feb 21.

Stokes Laboratories, Bernal Institute, School of Engineering, University of Limerick, Ireland. Electronic address:

Menisci play a major role in the mechanical function of the knee. They are subjected to large compressive forces and as a result and due to its avascular structure, menisci are prone to irreparable damage. Meniscectomy was once a common procedure for damaged menisci, however alternative approaches involving meniscus regeneration to restore function are of current interest. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.02.020DOI Listing

Effect of ice quenching after oxidation with or without vacuum on the hardness of Pd-Ag-Au-In alloy during porcelain firing simulation.

J Mech Behav Biomed Mater 2019 Jun 9;94:93-109. Epub 2019 Mar 9.

Department of Dental Materials, Institute of Translational Dental Science and BK21 PLUS Project, School of Dentistry, Pusan National University, Beomeo-Ri, Mulgeum-Eup, Yangsan-Si, Gyeongsangnam-Do 626-814, South Korea. Electronic address:

This study examined the effect of ice-quenching after oxidation treatment with or without vacuum, on the change in the hardness of a Pd-Ag-Au-In metal-ceramic alloy during porcelain-firing simulation. The aim of the present study is to determine whether ice quenching after oxidation renders a Pd-Ag metal-ceramic alloy soft enough for easy processing without the need for an additional solution treatment and whether it affects the final hardness of the Pd-Ag metal-ceramic alloy after porcelain firing simulation. The oxidation treatment resulted in the as-cast specimen becoming homogenized, which was progressed further by vacuuming. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.03.006DOI Listing

Experimental and finite element analyses of bone strains in the growing rat tibia induced by in vivo axial compression.

J Mech Behav Biomed Mater 2019 Jun 13;94:176-185. Epub 2019 Mar 13.

Department of Mechanical Engineering, École Polytechnique of Montréal, P.O. Box 6079, Station Centre-Ville, Montréal, Québec, Canada H3C 3A7; Sainte-Justine University Hospital Center, 3175 Côte-Sainte-Catherine Rd., Montréal, Québec, Canada H3T 1C5. Electronic address:

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http://dx.doi.org/10.1016/j.jmbbm.2019.03.009DOI Listing

A viscoelastic nonlinear compressible material model of lung parenchyma - Experiments and numerical identification.

J Mech Behav Biomed Mater 2019 Jun 22;94:164-175. Epub 2019 Feb 22.

Institute for Computational Mechanics, Technical University of Munich, Boltzmannstr. 15, 85747 Garching b. München, Germany.

Characterizing material properties of lung parenchyma is essential in order to describe and predict the mechanical behavior of the lung in health and disease. Hence, we aim to identify the viscoelastic constitutive behavior of viable lung parenchyma with a particular focus on the nonlinear, compressible, and frequency-dependent material properties. To quantify the viscoelastic material behavior of rat lung parenchyma experimentally, we performed uniaxial tension tests with different frequencies, including the whole range of physiological frequencies, in combination with full-field displacement measurements (a total of 120 tests on 30 samples of 5 rats). Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.02.024DOI Listing

Mechanical properties of Chamelea gallina shells at different latitudes.

J Mech Behav Biomed Mater 2019 Jun 1;94:155-163. Epub 2019 Mar 1.

Laboratory of Bio-Inspired & Graphene Nanomechanics, Department of Civil, Environmental and Mechanical Engineering, University of Trento, Via Mesiano 77, 38123 Trento, Italy; Ket Lab, Edoardo Amaldi Foundation, Via del Politecnico snc, 00133 Rome, Italy; School of Engineering and Materials Science, Queen Mary University of London, Mile End Road, E1-4NS London, United Kingdom. Electronic address:

In this work we evaluate the mechanical properties of Chamelea gallina shells, collected at various locations in the Adriatic Sea, through compression tests. We present an analytical model for the extraction of the material Young's modulus and ultimate strength, based on the approximation of the valves with a simpler geometry. The effect of porosity and the computation of the energy dissipated at fracture are also discussed. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.02.032DOI Listing

CAD-CAM milled versus pressed lithium-disilicate monolithic crowns adhesively cemented after distinct surface treatments: Fatigue performance and ceramic surface characteristics.

J Mech Behav Biomed Mater 2019 Jun 9;94:144-154. Epub 2019 Mar 9.

MSciD Graduate Program, School of Dentistry, Meridional Faculty - IMED, Passo Fundo, Rio Grande do Sul State, Brazil. Electronic address:

To evaluate the fatigue failure load (FFL), number of cycles for failure (CFF) and survival probabilities of lithium-disilicate (LD) monolithic crowns manufactured by two processing techniques (pressing vs. CAD/CAM) adhesively cemented to a dentin-analogue material, considering two surface treatments (conventional vs. simplified). Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.03.005DOI Listing

A coupled approach for identification of nonlinear and compressible material models for soft tissue based on different experimental setups - Exemplified and detailed for lung parenchyma.

J Mech Behav Biomed Mater 2019 Jun 20;94:126-143. Epub 2019 Feb 20.

Institute for Computational Mechanics, Technical University of Munich, Boltzmannstr. 15, 85747 Garching b. München, Germany.

In this paper, a coupled inverse analysis is proposed to identify nonlinear compressible hyperelastic material models described by two sets of experiments. While the overall approach is applicable for different materials, here it will be presented for viable lung parenchyma. Characterizing the material properties of lung parenchyma is essential to describe and predict the mechanical behavior of the respiratory system in health and disease. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17516161183130
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http://dx.doi.org/10.1016/j.jmbbm.2019.02.019DOI Listing
June 2019
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Development of novel zirconia implant's materials gradated design with improved bioactive surface.

J Mech Behav Biomed Mater 2019 Jun 20;94:110-125. Epub 2019 Feb 20.

Center for Micro-Electro-Mechanical Systems (CMEMS-UMinho), University of Minho, Campus de Azurém, 4800-058 Guimarães, Portugal.

Zirconia implants are becoming a preference choice for different applications such as knee, dental, among others. In order to improve osseointegration, implant's surfaces are usually coated with bioactive materials like hydroxyapatite (HAp) and beta-tricalcium phosphate (β-TCP) that are very similar to the calcium phosphates found in bones. However, due to the implantation process, these coatings can be detached from the zirconia surface, leading to implant premature failure. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.02.022DOI Listing

Fretting-corrosion behavior on dental implant connection in human saliva.

J Mech Behav Biomed Mater 2019 Jun 26;94:86-92. Epub 2019 Feb 26.

Mines Saint-Etienne, Univ Lyon, Univ Jean Monnet, INSERM, U 1059 Sainbiose, Centre CIS, Departement StBio, F - 42023 Saint-Etienne, France. Electronic address:

Fretting-corrosion has been pointed out as failure mechanism in dental implants between the implant part and the abutment. Depending on countries, surgical habits, 4 combinations of materials, are well used. The behavior of fretting corrosion of these four combinations of materials have been highlighted: pure titanium (Ti-grade 4) against titanium alloy (Ti-6Al-4V); titanium alloy (Ti-6Al-4V); against titanium alloy (Ti-6Al-4V); pure titanium against zirconia stabilized with Yttria (Y-TZP) and titanium alloy (Ti-6Al-4V) against zirconia (Y-TZP). Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.02.025DOI Listing
June 2019
1 Read