27,554,110 results match your criteria Journal of the Japan Diabetes Society [Journal]

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Reactivity of 4-thiothymidine with Fenton's reagent investigated by UV-Visible Spectroscopy and ElectroSpray Ionization Mass Spectrometry.

J Mass Spectrom 2019 Feb 15. Epub 2019 Feb 15.

Dipartimento di Chimica, Università degli Studi di Bari "Aldo Moro", Via Orabona, 4-70126, Bari, Italy.

The reactivity of the sulfur-containing nucleoside 4-thio-(2'-deoxy)-thymidine (S -TdR) under Fenton conditions, i.e. in the presence of H O and catalytic amounts of Fe (II), was investigated by UV-Vis spectroscopy and ElectroSpray Ionization Single and Tandem Mass Spectrometry (ESI-MS and MS/MS). Read More

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http://dx.doi.org/10.1002/jms.4343DOI Listing
February 2019

DFT computational schemes for N NMR chemical shifts of the condensed nitrogen containing heterocycles.

Magn Reson Chem 2019 Feb 15. Epub 2019 Feb 15.

A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences, Favorsky St. 1, 664033, Irkutsk, Russian Federation.

A systematic DFT study of the accuracy factors (functionals, basis sets, solvent effects) for the computation of N NMR chemical shifts has been performed in the series of condensed nitrogen containing heterocycles. The behavior of the most representative functionals was examined based on the benchmark calculations of N NMR chemical shifts in the reference set of compounds. It was found that the best agreement with experiment was achieved with OLYP functional in combination with aug-pcS-3(N)//pc-2 locally dense basis set scheme providing MAE of 5. Read More

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http://dx.doi.org/10.1002/mrc.4851DOI Listing
February 2019

45. Jahrestagung der Rheinisch-Westfälischen Gesellschaft für Nuklearmedizin (RWGN).

Authors:

Nuklearmedizin 2019 Feb 15;58(1):56. Epub 2019 Feb 15.

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http://dx.doi.org/10.1055/a-0824-8173DOI Listing
February 2019

NuklearMedizin 2019 in Bremen.

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Nuklearmedizin 2019 Feb 15;58(1):55-56. Epub 2019 Feb 15.

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http://dx.doi.org/10.1055/a-0824-8119DOI Listing
February 2019

Neuer DGN-Vorstand nimmt seine Arbeit auf.

Authors:

Nuklearmedizin 2019 Feb 15;58(1):53-55. Epub 2019 Feb 15.

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http://dx.doi.org/10.1055/a-0824-8095DOI Listing
February 2019

Iodine Avid Papillary Thyroid Cancer Showing PSMA-Expression in 68Ga-PSMA Ligand PET/CT.

Nuklearmedizin 2019 Feb 15;58(1):50-51. Epub 2019 Feb 15.

Klinikum der Johann Wolfgang Goethe-Universität Frankfurt, Klinik für Nuklearmedizin.

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http://dx.doi.org/10.1055/a-0808-0832DOI Listing
February 2019

Normal Values for Parotid Gland and Submandibular-Sublingual Salivary Gland Complex Uptake of 99mTechnetium Pertechnetate using SPECT in Mice with Respect to Age, Sex, and Circadian Rhythm.

Nuklearmedizin 2019 Feb 15;58(1):39-49. Epub 2019 Feb 15.

Berlin Experimental Radionuclide Imaging Center (BERIC), Charité - Universitätsmedizin Berlin.

Aim: The aim of this study was to establish normal values for parotid gland (PG) and submandibular-sublingual salivary gland complex (SSC) uptake of technetium pertechnetate (TcO) as a function of age, sex and circadian rhythm in mice.

Methods: In 12 female (F) and 12 male (M) C57BL/6N mice, nine consecutive SPECT images of 10 min each were acquired as dynamic acquisitions beginning 5 min after intravenous injection of 80 MBq TcO. Each mouse was imaged in follow-up studies at 1, 3, 6, 12 and 24 months of age. Read More

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http://dx.doi.org/10.1055/a-0810-0174DOI Listing
February 2019

Response of locally advanced rectal cancer (LARC) to radiochemotherapy: DW-MRI and multiparametric PET/CT in correlation with histopathology.

Nuklearmedizin 2019 Feb 15;58(1):28-38. Epub 2019 Feb 15.

Lausanne University Hospital, Diagnostic and Interventional Radiology.

Aim: To prospectively evaluate histological significance and predictive value of changes in apparent diffusion coefficient (ADC) and F-FDG PET/CT parameters in locally advanced rectal cancer (LARC) after neoadjuvant radiochemotherapy (RCT).

Methods: Twenty-one patients with untreated LARC underwent pre-RCT and post-RCT F-FDG PET/CT and diffusion-weighted magnetic resonance imaging (DW-MRI), followed by surgery. For both datasets, two readers measured the tumor SUVmax, SUVmean, MTV, TLG, ADCmin, ADCmean, and respective differences (∆SUVmax, ∆SUVmean, ∆MTV, ∆TLG, ∆ADCmin, ∆ADCmean) for the whole tumor. Read More

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http://dx.doi.org/10.1055/a-0809-4670DOI Listing
February 2019

Intraindividual comparison of selective intraarterial versus systemic intravenous 68Ga-DOTATATE PET/CT in patients with inoperable meningioma.

Nuklearmedizin 2019 Feb 15;58(1):23-27. Epub 2019 Feb 15.

Department of Diagnostic and Interventional Neuroradiology, RWTH University Hospital Aachen.

Aim: Here we describe the results of superselective intraarterial application of diagnostic Ga-68-DOTA0,Tyr3-octreotate (Ga-68-DOTATATE) in a series of patients with inoperable WHO grade II meningiomas which were no longer amenable to radiotherapy.

Methods: Four patients with inoperable WHO grade II meningioma underwent systemic venous infusion of Ga-68-DOTATATE followed by PET/CT. Ga-68-DOTATATE application was repeated intraarterially via transfemoral catheterization of vessels supplying the meningioma and another PET/CT was performed. Read More

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http://dx.doi.org/10.1055/a-0802-5039DOI Listing
February 2019

Influence of 18F-FDG-PET/CT on staging of cervical cancer.

Nuklearmedizin 2019 Feb 15;58(1):17-22. Epub 2019 Feb 15.

Chair and Department of Electroradiology, Poznan University of Medical Science.

Aim: Cervical cancer is one of the most common cancers of the female reproductive system. The aim of the study was to assess the usefulness of the F-FDG-PET/CT study in staging of cervical cancer, with focus on the primary tumor parameters.

Material & Methods: 105 patients (mean age 56 ± 11y) with newly diagnosed cervical cancer underwent PET/CT examination which was performed 60 min after IV injection of F-FDG with a mean activity of 364 ± 75MBq. Read More

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http://dx.doi.org/10.1055/a-0809-4577DOI Listing
February 2019

[Dopamine Transporter SPECT with I-123 labelled FP-CIT (DaTSCANTM)].

Nuklearmedizin 2019 Feb 15;58(1):5-16. Epub 2019 Feb 15.

Universitätsklinikum Freiburg, Klinik für Nuklearmedizin.

The aim of the S1 guideline is to assist in establishing the indication and in performing, interpreting and reporting SPECT investigations of the dopamine transporter (DAT) with DaTSCAN. Compared to the preceding version dated from 2007 the current update considers relevant new publications, the guidelines of the European (EANM) and Society of Nuclear Medicine (SNM), and the current version of the S3 guideline of the German Society of Neurology on "Idiopathic Parkinsonsian Syndrome". In addition new technical developments are incorporated. Read More

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http://dx.doi.org/10.1055/a-0807-8137DOI Listing
February 2019

Increasing the Chances of Natural Conception: Opinion Statement from the the Brazilian Federation of Gynecology and Obstetrics Associations Committee on Endocrine Gynecology.

Rev Bras Ginecol Obstet 2019 Feb 15. Epub 2019 Feb 15.

Faculty of Medical Sciences, Universidade de Pernambuco, Recife, PE, Brazil.

Considering that myths and misconceptions regarding natural procreation spread rapidly in the era of easy access to information and to social networks, adequate counseling about natural fertility and spontaneous conception should be encouraged in any kind of health assistance. Despite the fact that there is no strong-powered evidence about any of the aspects related to natural fertility, literature on how to increase the chances of a spontaneous pregnancy is available. In the present article, the Brazilian Federation of Gynecology and Obstetrics Associations (FEBRASGO, in the Portuguese acronym) Committee on Endocrine Gynecology provides suggestions to optimize counseling for non-infertile people attempting spontaneous conception. Read More

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http://dx.doi.org/10.1055/s-0039-1677838DOI Listing
February 2019

Endovascular Repair of Aortic Arch Aneurysm with Surgeon-Modified Fenestrated Stent Graft.

Authors:
Jesse Manunga

Aorta (Stamford) 2018 Apr 15;6(2):70-74. Epub 2019 Feb 15.

Department of Vascular and Endovascular Surgery, Minneapolis Heart Institute at Abbott Northwestern Hospital, Minneapolis, Minnesota.

The authors describe a technique of treating patients with aortic arch aneurysm using surgeon-modified fenestrated stent graft (SMFSG). The technique is demonstrated in a 80-year-old patient whose aneurysm was successfully excluded with a SMFSG using Cook Alpha thoracic stent graft. The device was deployed, removed from its delivery system, and a fenestration created before being mounted back on the delivery system and constrained. Read More

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http://dx.doi.org/10.1055/s-0039-1677810DOI Listing

Imaging, Surgical, and Pathology Findings of a Myxoid Aortic Sarcoma: When Distal Embolization Uncovers a Bigger Problem.

Aorta (Stamford) 2018 Apr 15;6(2):65-67. Epub 2019 Feb 15.

Division Cardiac Surgery, Indiana University, Indianapolis, Indiana.

Aortic sarcomas are a very rare condition typically characterized by a deceiving presentation. Making a correct diagnosis is based on the application of an algorithm which allows to identify the primary disease site and to obtain a tissue diagnosis. Surgical aortic resection with adjuvant therapy offers the best palliation, particularly in cases of well-differentiated tumors with no evidence of diffuse metastatic spread. Read More

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http://dx.doi.org/10.1055/s-0039-1678548DOI Listing

Evaluation of BioFoam for Anastomotic Bleeding in Cardiovascular Surgery.

Authors:
Ottavio Alfieri

Aorta (Stamford) 2018 Apr 15;6(2):53-58. Epub 2019 Feb 15.

Department of Cardiac Surgery, Ospedale San Raffaele, Milan, Italy.

Background:  Hemostatic agents are increasingly used as an adjunct to standard methods of controlling anastomotic bleeding in surgical procedures. The purpose of this study was to investigate the safety and effectiveness of BioFoam Surgical Matrix used as an adjunct for anastomotic hemostasis following cardiovascular surgery.

Methods:  A prospective, multicenter, single arm study was conducted with 75 subjects treated with BioFoam following a total of 105 elective cardiovascular surgical procedures. Read More

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http://dx.doi.org/10.1055/s-0039-1678549DOI Listing

Endocannabinoid Signalling in Atherosclerosis and Related Metabolic Complications.

Thromb Haemost 2019 Feb 15. Epub 2019 Feb 15.

Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-University (LMU) Munich, Munich, Germany.

Endocannabinoids are a group of arachidonic acid-derived lipid mediators binding to cannabinoid receptors CB1 and CB2. An overactivity of the endocannabinoid system plays a pathophysiological role in the development of visceral obesity and insulin resistance. Moreover, elevated circulating endocannabinoid levels are also prevalent in atherosclerosis. Read More

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http://dx.doi.org/10.1055/s-0039-1678738DOI Listing
February 2019

Increased Leucocyte-Platelet Complex Formation in Recently Symptomatic versus Asymptomatic Carotid Stenosis Patients and in Micro-emboli Negative Subgroups.

Thromb Haemost 2019 Feb 15. Epub 2019 Feb 15.

Department of Neurology, Adelaide and Meath Hospital, Dublin, incorporating the National Children's Hospital (AMNCH)/Tallaght University Hospital, Dublin, Ireland.

Introduction:  Cerebral micro-embolic signals (MES) predict risk of stroke in carotid stenosis patients. However, MES-negative 'recently symptomatic patients' also have a higher stroke risk than 'asymptomatic patients'. Differences in platelet activation status may contribute to this disparity in risk. Read More

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http://dx.doi.org/10.1055/s-0039-1678666DOI Listing
February 2019

Acknowledgement to reviewers for UiM/EJU in 2018.

Authors:

Ultraschall Med 2019 Feb 15;40(1):88-89. Epub 2019 Feb 15.

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http://dx.doi.org/10.1055/a-0824-8979DOI Listing
February 2019

What Ultrasound Operators Must Be Well Aware of in a World With Raising Burden of Non Alcoholic Fatty Liver Disease?

Ultraschall Med 2019 Feb 15;40(1):7-10. Epub 2019 Feb 15.

Unit of Radiology, University La Sapienza Rome, Italy.

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http://dx.doi.org/10.1055/a-0808-8062DOI Listing
February 2019

[Rehabilitation for Patients with Orphan Diseases: Vasculitis of Small Vessels].

Rehabilitation (Stuttg) 2019 Feb 15;58(1):59-72. Epub 2019 Feb 15.

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http://dx.doi.org/10.1055/a-0750-9515DOI Listing
February 2019

[Propensity Score Methods to Estimate Treatment Effects: An Opportunity for Rehabilitation Service Research].

Rehabilitation (Stuttg) 2019 Feb 15;58(1):50-58. Epub 2019 Feb 15.

Institut für Sozialmedizin und Epidemiologie, Sektion Rehabilitation und Arbeit, Universität zu Lübeck.

The randomized controlled trial is the gold standard to validate the efficacy of an intervention. Randomized treatment assignment in intervention and control group independent of patient characteristics or previous measures of patient care allows one to estimate unbiased treatment effects. Differences in outcomes can be attributed causally to the treatment. Read More

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http://dx.doi.org/10.1055/a-0781-8967DOI Listing
February 2019

Herausfordernde Blutzuckereinstellung bei einer frisch lebertransplantierten Diabetikerin in der Anschlussrehabilitation.

Authors:

Rehabilitation (Stuttg) 2019 Feb 15;58(1):12-14. Epub 2019 Feb 15.

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http://dx.doi.org/10.1055/a-0810-3856DOI Listing
February 2019

Wunsch- und Wahlrecht, insbesondere bei Leistungen zur medizinischen Rehabilitation.

Rehabilitation (Stuttg) 2019 Feb 15;58(1):7-11. Epub 2019 Feb 15.

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http://dx.doi.org/10.1055/a-0825-8486DOI Listing
February 2019

Zur Nachhaltigkeit des Erfolges in der Rehabilitation.

Authors:
Uwe Koch

Rehabilitation (Stuttg) 2019 Feb 15;58(1). Epub 2019 Feb 15.

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http://dx.doi.org/10.1055/a-0834-6983DOI Listing
February 2019

[Violence in the Emergency Medicine (Emergency Rescue Service and Emergency Departments) - Current Situation in Germany].

Anasthesiol Intensivmed Notfallmed Schmerzther 2019 Feb 15;54(2):146-154. Epub 2019 Feb 15.

Background: During the last years healthcare personnel is more often faced with different degrees of violence and aggression while doing their jobs. However, systematic data with respect to offender profiles, reasons, frequency and types of violence in emergency medicine in Germany has not been systematically analyzed.

Aim: The aim of this article is to overview the data of present German studies. Read More

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http://dx.doi.org/10.1055/s-0043-112189DOI Listing
February 2019

[Coffee, Cigarettes, Chewing Gum - Myths and Facts About Preoperative Fasting].

Anasthesiol Intensivmed Notfallmed Schmerzther 2019 Feb 15;54(2):142-145. Epub 2019 Feb 15.

Consumption of clear liquids (including coffee and orange juice without pulp) up to 2 hours before the start of anaesthesia is unproblematic. Contrary to the recommendations of the professional societies, the intake of beverages containing milk (up to 50% of the total volume) in small quantities seems to be harmless. Drinks containing alcohol can considerably delay emptying of the stomach. Read More

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http://dx.doi.org/10.1055/s-0043-124943DOI Listing
February 2019

[Focused Abdominal Ultrasound in Emergency, Perioperative and Intensive Care Medicine].

Anasthesiol Intensivmed Notfallmed Schmerzther 2019 Feb 15;54(2):128-141. Epub 2019 Feb 15.

The rising impact of perioperative sonography is mainly based on mobile high quality ultrasound systems. Relevant bleedings or functional limitations of the abdomen are easy to identify with sonography. The FAST-Concept can be the first access to continue proceedings in ultrasound examination of the abdomen. Read More

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http://dx.doi.org/10.1055/a-0585-5237DOI Listing
February 2019

[Lung Ultrasound for Anesthesia, Intensive Care and Emergency Medicine].

Anasthesiol Intensivmed Notfallmed Schmerzther 2019 Feb 15;54(2):108-127. Epub 2019 Feb 15.

Lung ultrasound is an underrated tool in preclinical emergency situations, intensive care units, ORs and emergency rooms. For certain clinical questions, there is a drastically higher sensitivity in comparison to chest X-ray examinations (sensitivity in pneumothorax diagnostics 86 vs. 28%, specificity 97 vs. Read More

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http://dx.doi.org/10.1055/a-0664-5700DOI Listing
February 2019

[Focused Transthoracic Echocardiography in the Perioperative Setting].

Anasthesiol Intensivmed Notfallmed Schmerzther 2019 Feb 15;54(2):90-106. Epub 2019 Feb 15.

With focused transthoracic echocardiography (TTE) we rapidly and non-invasively receive up-to-date information on a patient's hemodynamic status. These can subsequently influence our therapy and thus our risk management. Postoperatively, TTE has proved its worth as an examination method in the recovery room and in the intensive care unit to promptly diagnose life-threatening causes of circulatory depression. Read More

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http://dx.doi.org/10.1055/a-0586-6146DOI Listing
February 2019

Ultraschall in AINS.

Anasthesiol Intensivmed Notfallmed Schmerzther 2019 Feb 15;54(2):88-89. Epub 2019 Feb 15.

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http://dx.doi.org/10.1055/a-0805-2279DOI Listing
February 2019

The Who, What, and Where of Primary TKAs: An Analysis of HCUP Data from 2009 to 2015.

J Knee Surg 2019 Feb 15. Epub 2019 Feb 15.

Department of Orthopedics, Duke University School of Medicine, Durham, North Carolina.

The aim of this study was to assess (1) temporal trends, (2) primary indication, (3) patient-level demographics (age, race, gender, health status, and median income quartile), and (4) region and hospital type for all patients receiving primary total knee arthroplasty (TKA) between 2009 and the third quarter of 2015. The National Inpatient Sample Database (NIS) was used to identify all patients who underwent a TKA between 2009 and the third quarter of 2015. Regression analysis was utilized to assess trends. Read More

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http://dx.doi.org/10.1055/s-0039-1677857DOI Listing
February 2019

Correction: Novel PDE6B Mutation Presenting with Retinitis Pigmentosa - A Case Series of Three Patients.

Klin Monbl Augenheilkd 2019 Feb 15. Epub 2019 Feb 15.

Unité d'oculogénétique, Hôpital ophtalmique Jules-Gonin, Lausanne, Switzerland.

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http://dx.doi.org/10.1055/a-0853-8855DOI Listing
February 2019

The impact of interventions by pharmacists collected in a computerised physician order entry context: a prospective observational study with a 10-year reassessment.

Swiss Med Wkly 2019 Feb 15;149:w20015. Epub 2019 Feb 15.

Pharmacy Department, Georges-Pompidou European Hospital, APHP, Paris, France / Equipe 22, Centre de Recherche des Cordeliers, UMR, INSERM, Paris, France.

Aims Of The Study: This study assesses clinical interventions by pharmacists prospectively collected from medical and surgical wards, notably the acceptance of interventions, computerised physician order entry (CPOE)related problems, the potential impact of interventions on patient safety evaluated by a multidisciplinary committee, and their evolution over the 10 years since a first assessment.

Methods: A prospective observational study covering 13 months was conducted in a French teaching hospital with a patient information system that integrates an electronic health record (EHR) with a CPOE. Interventions by pharmacists were prospectively recorded using CPOE. Read More

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http://dx.doi.org/10.4414/smw.2019.20015DOI Listing
February 2019

Variations of care and diagnosis as markers for the quality of medical care in Switzerland.

Swiss Med Wkly 2019 Feb 15;149:w20029. Epub 2019 Feb 15.

University Hospital Basel, Switzerland.

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http://dx.doi.org/10.4414/smw.2019.20029DOI Listing
February 2019

Assessment of voluntary HIV screening for asylum seekers in two Swiss cantons.

Swiss Med Wkly 2019 Feb 15;149:w20020. Epub 2019 Feb 15.

Department of Infectious Diseases, Central Institute, Valais Hospital, Sion, Switzerland / Departments of Infectious Diseases and of Preventive Medicine, Lausanne University Hospital, Lausanne, Switzerland.

Objective: To evaluate the feasibility of HIV screening, offered to newly arrived asylum seekers in the Swiss cantons of Valais (VS) and Vaud (VD) in order to meet the national and international standards for early detection and effective treatment of HIV infections.

Methods: HIV screening was offered free of charge to every asylum seeker who arrived from June 2015 to November 2016 in VS, and from June to October 2016 in VD. Pregnant women and children <16 were excluded. Read More

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http://dx.doi.org/10.4414/smw.2019.20020DOI Listing
February 2019

Association between different types of plant-based diets and leptin levels in healthy volunteers.

Acta Biochim Pol 2019 Feb 15. Epub 2019 Feb 15.

of Clinical Nutrition and Dietetics, Faculty of Health Sciences, Medical University of Gdańsk, Gdańsk, Poland.

Leptin is an important factor regulating appetite and energety metabolism; disturbances in its signaling are related to adiposity and contribute to the excessive body fat. About a third of the human population is overweight or suffers from obesity, as well as from associated medical conditions. It is well established that vegetarian, especially vegan, diet is very effective in lowering BMI and body fat, thus, plant-based diets are associated with a lower risk of obesity. Read More

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http://dx.doi.org/10.18388/abp.2018_2725DOI Listing
February 2019

Facile single-molecule pull-down assay for analysis of endogenous proteins.

Phys Biol 2019 Feb 15. Epub 2019 Feb 15.

CREOL, The College of Optics and Photonics, University of Central Florida, Orlando, Florida, UNITED STATES.

The single-molecule pull-down (SiMPull) assay analyzes molecular complexes in physiological conditions from cell or tissue lysates. Currently the approach requires a lengthy sample preparation process, which has largely prevented the widespread adoption of this technique in bioanalysis. Here, we present a simplified SiMPull assay based upon dichlorodimethylsilane - Tween-20 passivation and F(ab) fragment labeling. Read More

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http://dx.doi.org/10.1088/1478-3975/ab0792DOI Listing
February 2019

Selective photochromism in self-coated WO3/WO3-x homojunction: enhanced solar modulation efficiency, high luminous transmittance and fast self-bleaching rate.

Nanotechnology 2019 Feb 15. Epub 2019 Feb 15.

Shanghai Institute of Ceramics Chinese Academy of Sciences, Changning District, Shanghai, CHINA.

Pursuing excellent photochromic (PC) property is still a longstanding challenge for energy-efficient smart coatings. Herein, we have prepared a novel series of self-coated crystalline WO3-amorphous WO3-x homojunction by one-step hydrothermal process, in which oxalic acid was used for a capping agent to prevent polycondenstation and crystallization of [WO6]. The as-prepared nanopowders have large specific surface area and rich surface electron, which lead to a dramatic photochromic property reaching up to △Tsol=64. Read More

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http://dx.doi.org/10.1088/1361-6528/ab0778DOI Listing
February 2019

Large area patterning of residue-free metal oxide nanostructures by Liquid Transfer Imprint Lithography.

Nanotechnology 2019 Feb 15. Epub 2019 Feb 15.

Nanomechanical System Research Division, Korea Institute of Machinery and Materials, Jang-dong, Yuseong-gu, Daejeon 305-343, KOREA, DaeJeon, 305-600, KOREA, REPUBLIC OF.

One-dimensional and three-dimensional residue-free metal oxide patterns are directly fabricated over large areas using liquid transfer imprint lithography (LTIL) with an ultraviolet (UV)-curable metal oxide precursor resist. A one-dimensional line or pillar array of metal oxides nano-patterns without a residual layer is formed by LTIL and annealing processes. A three-dimensional layer-by-layer nanomesh structure is successfully constructed by repeating the LTIL method without a complex etching process. Read More

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http://dx.doi.org/10.1088/1361-6528/ab077dDOI Listing
February 2019

Design of a multi-analyte resonant photonic platform for label-free biosensing.

Nanotechnology 2019 Feb 15. Epub 2019 Feb 15.

Key Laboratory for Physical Electronics and Devices of the Ministry of Education, Xi'an Jiaotong University, 710049, P. R. China, Xi'an, CHINA.

We have designed a multi-analyte biosensing platform based on a hybrid whispering gallery mode resonator to detect protein biomarkers, e.g. those allowing the early diagnosis of Alzheimer's disease. Read More

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http://dx.doi.org/10.1088/1361-6528/ab0771DOI Listing
February 2019

Bioprinted osteon-like scaffolds enhance in vivo neovascularization.

Biofabrication 2019 Feb 15. Epub 2019 Feb 15.

Fischell Department of Bioengineering, University of Maryland, college park, Maryland, UNITED STATES.

Bone tissue engineers are facing a daunting challenge when attempting to fabricate bigger constructs intended for use in the treatment of large bone defects, which is the vascularization of the graft. Cell-based approaches and, in particular, the use of in vitro coculture of human umbilical vein endothelial cells (HUVECs) and human mesenchymal stem cells (MSCs) has been one of the most explored options. We present in this paper an alternative method to mimic the spatial pattern of HUVECs and hMSCs found in native osteons based on the use of extrusion-based 3D bioprinting (3DP). Read More

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http://dx.doi.org/10.1088/1758-5090/ab078aDOI Listing
February 2019

Thermal transport in C3N nanotube: a comparative study with carbon nanotube.

Authors:
Xu Cheng Xinyu Wang

Nanotechnology 2019 Feb 15. Epub 2019 Feb 15.

Institute of Thermal Science and Technology, Shandong University, 17923 Jinshi Road, Jinan, Shandong Province, 250061, CHINA.

One-dimensional nanotubes, such as, carbon nanotube (CNT) and C3N nanotube (C<sub>3</sub>NNT), are attracting growing research interest due to their excellent electrical and thermal properties. In this work, thermal transport of single-walled C<sub>3</sub>NNT is investigated in comparison with the single-walled CNT using classical molecular dynamics (MD) simulations. We firstly observe that the thermal conductivity (<i>k</i>) of C<sub>3</sub>NNT is lower than that of CNT. Read More

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http://dx.doi.org/10.1088/1361-6528/ab077aDOI Listing
February 2019

Native aortic valve derived extracellular matrix hydrogel for three dimensional culture analyses with improved biomimetic properties.

Biomed Mater 2019 Feb 15. Epub 2019 Feb 15.

Research Group for Experimental Surgery, Department of Cardiovascular Surgery, Medical Faculty, Heinrich Heine University Duesseldorf,, Düsseldorf, GERMANY.

Introduction Calcific aortic valve disease (CAVD) is the most common acquired heart valve disease with complex underlying pathomechanisms that are yet not fully understood. Three-dimensional (3D) cell culture models as opposed to conventional two-dimensional (2D) techniques may reveal new aspects of CAVD and serve as a transitional platform between conventional 2D cell culture and in vivo experiments. Methods Here we report on fabrication and characterization of a novel 3D hydrogel derived from cell-free native aortic valves. Read More

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http://dx.doi.org/10.1088/1748-605X/ab0791DOI Listing
February 2019

One step synthesis of PANI/Fe2O3 nanocomposites and flexible film for enhanced NH3 sensing performance at room temperature.

Nanotechnology 2019 Feb 15. Epub 2019 Feb 15.

Institute of Polymer Product Engineering, Linz, AUSTRIA.

Novel sea cucumber-shaped polyaniline/ferric oxide (PANI/Fe2O3) nanocomposites were synthesized using a simple and efficient one-step hydrothermal process, and further assembling the nanocomposites onto a polyethylene terephthalate (PET) flexible substrate. Through monitoring the resistance of the PANI/Fe2O3 nanocomposites thick film and PANI/Fe2O3-PET flexible sensors, the responses of the sensors are obtained to various 100 ppm gases including methanol, triethylamine, aniline and other five gases. It is found that two kinds of sensors exhibit a high selectivity towards NH3. Read More

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http://dx.doi.org/10.1088/1361-6528/ab076eDOI Listing
February 2019

A mixed-integer linear programming optimization model framework for capturing expert planning style in low dose rate prostate brachytherapy.

Phys Med Biol 2019 Feb 15. Epub 2019 Feb 15.

Mechanical Engineering, University of Alberta, Edmonton, Alberta, CANADA.

Low dose rate (LDR) brachytherapy is a minimally invasive form of radiation therapy, used to treat prostate cancer, and it involves permanent implantation of radioactive sources (seeds) inside of the prostate gland. Treatment planning in brachytherapy involves a decision making process for the placement of the sources in order to deliver an effective dose of radiation to cancerous tissue in the prostate while sparing the surrounding healthy tissue. Such a decision making process can be modeled as a mixed-integer linear programming (MILP) problem. Read More

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http://dx.doi.org/10.1088/1361-6560/ab075cDOI Listing
February 2019

Role of grain boundaries in Ge-Sb-Te based chalcogenide superlattices.

J Phys Condens Matter 2019 Feb 15. Epub 2019 Feb 15.

I Physikalisches Institut der RWTH Aachen IA, Rheinisch - Westfalische Technische Hochschule Aachen, Aachen, GERMANY.

Interfacial phase change memory devices based on a distinct nanoscale structure called superlattice have been shown to outperform conventional phase-change devices. This improvement has been attributed to the hetero-interfaces, which play an important role for the superior device characteristics. However, the impact of grain boundaries, usually present in large amounts in a standard sputter-deposited superlattice film, on the device performance has not yet been investigated. Read More

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http://dx.doi.org/10.1088/1361-648X/ab078bDOI Listing
February 2019

ExCeL: Combining Extrusion printing on Cellulose scaffolds with Lamination to create in vitro biological models.

Biofabrication 2019 Feb 15. Epub 2019 Feb 15.

Department of Mechanical Engineering, McMaster University, Center for Advanced Micro-Electro-Fluidics, 1280 Main Street West, Hamilton, Ontario, CANADA L8S 4L7, Hamilton, CANADA.

Bioprinting is rapidly developing to be a powerful tool in tissue engineering for both whole tissue printing and development of in vitro models that can be used in drug discovery, toxicology and as in vitro bioreactors. Nevertheless, the ability to create complex 3D culture systems with different types of cells, extracellular matrices integrated with perfusable channels has been a challenge. Here we develop an approach that combines xurography of a scaffold material (cellulose) with extrusion printing of bioinks on it, followed by assembly in a layer by layer fashion to create complex 3D culture systems that could be used as in vitro models of biological processes. Read More

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http://dx.doi.org/10.1088/1758-5090/ab0798DOI Listing
February 2019

Generation of two isogenic iPSC lines with either a heterozygous or a homozygous E280A mutation in the PSEN1 gene.

Stem Cell Res 2019 Feb 7;35:101403. Epub 2019 Feb 7.

Bioneer A/S, Kogle Alle 2, 2970 Hørsholm, Denmark. Electronic address:

Alzheimer's disease (AD) is the most common form of dementia. Mutations in the gene PSEN1 encoding Presenilin1 are known to cause familial forms of AD with early age of onset. The most common mutation in the PSEN1 gene is the E280A mutation. Read More

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http://dx.doi.org/10.1016/j.scr.2019.101403DOI Listing
February 2019

Genetic diversity, antimicrobial resistance and virulence profile of Salmonella isolated from the peanut supply chain.

Int J Food Microbiol 2019 Feb 7;294:50-54. Epub 2019 Feb 7.

Faculty of Food Engineering, University of Campinas, Campinas, SP, Brazil. Electronic address:

Thirty-Eight Salmonella isolates recovered from different stages of the peanut supply chain in three Brazilian States (São Paulo, Minas Gerais and Bahia) were subtyped by pulsed-field gel electrophoresis (PFGE) and characterized by phenotypic and genotypic tests for antimicrobial resistance and virulence genes. The isolates were distributed into seven PFGE pulsotypes. All the isolates were resistant to sulfonamide. Read More

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http://dx.doi.org/10.1016/j.ijfoodmicro.2019.02.005DOI Listing
February 2019
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