704 results match your criteria Journal of the International Association of Physicians in AIDS Care[Journal]


Cryptococcal antigen screening and preemptive therapy in patients initiating antiretroviral therapy in resource-limited settings: a proposed algorithm for clinical implementation.

J Int Assoc Physicians AIDS Care (Chic) 2012 Nov-Dec;11(6):374-9. Epub 2012 Sep 26.

1Research Centre for Infection and Immunity, Division of Clinical Sciences, St. George's University of London, UK.

HIV-associated cryptococcal meningitis (CM) is estimated to cause over half a million deaths annually in Africa. Many of these deaths are preventable. Screening patients for subclinical cryptococcal infection at the time of entry into antiretroviral therapy programs using cryptococcal antigen (CRAG) immunoassays is highly effective in identifying patients at risk of developing CM, allowing these patients to then be targeted with "preemptive" therapy to prevent the development of severe disease. Read More

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http://dx.doi.org/10.1177/1545109712459077DOI Listing
February 2014
13 Reads

Factors associated with false-positive results from fingerstick OraQuick ADVANCE rapid HIV 1/2 antibody test.

J Int Assoc Physicians AIDS Care (Chic) 2012 Nov-Dec;11(6):356-60. Epub 2012 Sep 26.

1Boston University School of Medicine, Boston, MA, USA.

Objective: Identify factors associated with false-positive rapid HIV antibody tests.

Design: This retrospective cohort study with nested case-controls involved patients tested for HIV by Boston Medical Center (BMC) affiliates.

Methods: Cases had a reactive fingerstick OraQuick ADVANCE rapid HIV 1/2 antibody test and a negative Western blot. Read More

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http://dx.doi.org/10.1177/1545109712454194DOI Listing
February 2014
5 Reads

Greater acceptance of routine HIV testing (opt-out) by patients attending an infectious disease unit in Spain.

J Int Assoc Physicians AIDS Care (Chic) 2012 Nov-Dec;11(6):341-4. Epub 2012 Sep 10.

1Infectious Diseases Unit, Hospital Clinico San Juan, Alicante, Spain.

Objective: Our objective was to determine attitudes and opinions of patients seen in our ID Unit on conducting HIV testing universally.

Methods: The survey was conducted in patients between 18 and 65 years without known HIV infection. Requested information about the test was previous embodiment, reasons for rejection, opinion on the universal realization, benefits and/or drawbacks, possible test performance, and availability of results "test negative stigma. Read More

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http://dx.doi.org/10.1177/1545109712456879DOI Listing
February 2014
11 Reads

Once-daily nevirapine XR: a brief overview of the safety and efficacy of a new formulation.

J Int Assoc Physicians AIDS Care (Chic) 2012 Nov-Dec;11(6):369-73. Epub 2012 Aug 27.

1AIDS Healthcare Foundation, Los Angeles, CA, USA.

Nevirapine (NVP) was the first nonnucleoside reverse transcriptase inhibitor (NNRTI) approved by the US Food and Drug Administration (FDA) in 1996, for the treatment of HIV infection. Current treatment guidelines include NVP as a component of a recommended alternative NNRTI regimen, which may be the preferred regimen for patients with established cardiovascular risk factors since NVP has minimal untoward effects on serum lipids. Two randomized and controlled clinical trials established the noninferior virologic efficacy of twice-daily NVP versus ritonavir-boosted atazanavir (ATV/r), a protease inhibitor with limited effects on serum lipids, each drug on a background regimen of once-daily (QD) tenofovir (TDF)/emtricitabine (FTC). Read More

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http://dx.doi.org/10.1177/1545109712456427DOI Listing
February 2014
3 Reads

Thalidomide-associated thrombosis in the treatment of HIV-associated severe aphthous disease: a case report and review of the literature.

J Int Assoc Physicians AIDS Care (Chic) 2012 Nov-Dec;11(6):345-7. Epub 2012 Aug 27.

1Division of Infectious Diseases, Department of Internal Medicine, Rush University Medical Center, Chicago, IL, USA.

Venous thrombosis is a well-described complication of thalidomide therapy in patients with multiple myeloma (MM). However, an association between thalidomide use and thrombosis in HIV-positive patients has not been previously described. We present the case of a 48-year-old HIV-positive man who developed a deep venous thrombosis while on thalidomide for the treatment of severe aphthous ulcers. Read More

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http://dx.doi.org/10.1177/1545109712455460DOI Listing
February 2014
10 Reads

Choosing sides: HIV health care practices among shared populations of HIV-positive Latinos living near the US-Mexico border.

J Int Assoc Physicians AIDS Care (Chic) 2012 Nov-Dec;11(6):348-55. Epub 2012 Aug 27.

1Department of Medicine, Division of Global Public Health, University of California, San Diego, La Jolla, CA, USA.

Background: We compared HIV-positive patients receiving care in the border cities of San Diego, United States, with Tijuana, Mexico.

Methods: Participants were HIV-positive Latinos (n = 233) receiving antiretroviral therapy (ART) from San Diego-Tijuana clinics (2009-2010). Logistic regression identified correlates of receiving HIV care in San Diego versus Tijuana. Read More

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http://dx.doi.org/10.1177/1545109712453854DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422758PMC
February 2014
4 Reads

Sequential antiretroviral adherence: things to consider.

Authors:
Ehsan Chitsaz

J Int Assoc Physicians AIDS Care (Chic) 2012 Jul-Aug;11(4):217-8; author reply 219

1Yale University School of Medicine, Section of Infectious Diseases, Yale AIDS Program, New Haven, CT, USA.

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http://dx.doi.org/10.1177/1545109712444465DOI Listing
February 2014
2 Reads

Factors associated with reduced antituberculous serum drug concentrations in patients with HIV-TB coinfection.

J Int Assoc Physicians AIDS Care (Chic) 2012 Sep-Oct;11(5):273-6. Epub 2012 Aug 8.

1Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.

We describe correlates of reduced antituberculous serum drug concentrations (SDCs) in HIV-infected patients receiving treatment for active tuberculosis (TB). Cross-sectional analysis of individuals diagnosed with HIV and active TB in Northern Alberta, Canada, was performed. Of the 30 HIV-TB cases, 27 underwent measurement of SDCs. Read More

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http://dx.doi.org/10.1177/1545109712454454DOI Listing
February 2014
3 Reads

Demographic predictors of HIV serostatus among HIV counseling and testing clients in rural Nigeria.

J Int Assoc Physicians AIDS Care (Chic) 2012 Nov-Dec;11(6):366-8. Epub 2012 Aug 8.

1Institute of Human Virology, Abuja, Nigeria.

Nnewi is a rural Nigerian town with a human immunodeficiency virus (HIV) counseling and testing center which tests about 120 clients/d. The objective of this study is to determine the factors predicting positive HIV status at Nnewi. Review of records was done with age, gender, marital status, and occupation as variables. Read More

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http://dx.doi.org/10.1177/1545109712454193DOI Listing
February 2014
11 Reads

Epidemiology, responses, and way forward: the silent epidemic of viral hepatitis and HIV coinfection in Vietnam.

J Int Assoc Physicians AIDS Care (Chic) 2012 Sep-Oct;11(5):311-20. Epub 2012 Jul 24.

1World Health Organization Vietnam Country Office, Hanoi, Vietnam.

Viral hepatitis is a disease of great concern to public health that is now met by a favorable momentum to combat the global epidemic. This article is intended to highlight the importance of viral hepatitis in the Vietnam population as well in the group of people living with HIV/AIDS (PLWHA). We reviewed available data on epidemiology and response on hepatitis B virus (HBV) and hepatitis C virus (HCV) and HIV coinfection in Vietnam. Read More

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http://journals.sagepub.com/doi/10.1177/1545109712453939
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http://dx.doi.org/10.1177/1545109712453939DOI Listing
February 2014
37 Reads

Immune Reconstitution Inflammatory Syndrome (IRIS) with acute tuberculous osteomyelitis and disseminated mutilating tuberculous dactylitis in a person living with HIV and AIDS (PLHA): a case report.

J Int Assoc Physicians AIDS Care (Chic) 2012 Sep-Oct;11(5):289-92. Epub 2012 Jul 20.

1Center of Excellence for HIV and TB, Government Hospital of Thoracic Medicine, Tambaram, Chennai, Tamil Nadu, India.

HIV infection changed the scenario of infectious diseases. The pre-HAART (highly active antiretroviral therapy) era had resulted in new opportunistic infections. HIV and tuberculosis together had high mortality in countries with high prevalence of tuberculosis. Read More

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http://dx.doi.org/10.1177/1545109712449866DOI Listing
February 2014
13 Reads

Evaluation of a multimodal, distance learning HIV management course for clinical care providers in India.

J Int Assoc Physicians AIDS Care (Chic) 2012 Sep-Oct;11(5):277-82. Epub 2012 Jul 16.

1Division of Infectious Diseases, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.

Distance learning is an important tool for training HIV health workers. However, there is limited evidence on design and evaluation of distance learning HIV curricula and tools. We therefore designed, implemented, and evaluated a distance learning course on HIV management for clinical care providers in India. Read More

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http://dx.doi.org/10.1177/1545109712451330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856228PMC
February 2014
10 Reads

Clinical characteristics of HIV-infected patients who survive after the diagnosis of HIV infection for more than 10 years in a resource-limited setting.

J Int Assoc Physicians AIDS Care (Chic) 2012 Nov-Dec;11(6):361-5. Epub 2012 Jun 28.

1Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

A retrospective cohort study was conducted and 129 patients with a diagnosis of HIV infection for more than 10 years were identified. Half the patients were men and mean (standard deviation, SD) age at HIV diagnosis was 33.2 (9. Read More

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http://dx.doi.org/10.1177/1545109712449191DOI Listing
February 2014
2 Reads

Ocular complications of cryptococcal meningitis in patients with HIV: report of two cases and review of the literature.

J Int Assoc Physicians AIDS Care (Chic) 2012 Sep-Oct;11(5):283-8. Epub 2012 Jun 19.

1University of Toledo, Toledo, OH, USA.

AIDS-related cryptococcal meningitis can result in significant vision loss, but the risk factors, prognostic features, and optimal management of patients with ocular complications is unknown. We present 2 cases of blindness associated with cryptococcal meningitis and review the literature for associated cases. Twenty-six additional cases of vision deterioration or loss as a result of HIV-associated cryptococcal meningitis were reviewed. Read More

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http://dx.doi.org/10.1177/1545109712448537DOI Listing
February 2014
4 Reads

Prevalence of depressive and other central nervous system symptoms in HIV-infected patients treated with HAART in Spain.

J Int Assoc Physicians AIDS Care (Chic) 2012 Sep-Oct;11(5):321-8. Epub 2012 Jun 19.

1Hospital La Paz, Madrid, Spain.

This study was conducted to assess the prevalence of depressive symptoms, sleep disturbances, and subjective cognitive complaints in patients with HIV receiving highly active antiretroviral therapy. Participants completed the "Center for Epidemiological Studies Depression Scale" (CES-D) and a questionnaire on sleep disturbances and subjective cognitive complaints. Mean age of the 799 participants was 43. Read More

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http://dx.doi.org/10.1177/1545109712448217DOI Listing
February 2014
3 Reads

Increase in lymphogranuloma venereum cases in South Florida.

J Int Assoc Physicians AIDS Care (Chic) 2012 Jul-Aug;11(4):220-2. Epub 2012 Jun 4.

1Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.

The purpose of the study was to evaluate the clinic prevalence and clinical characteristics of patients with LGV since 2007 when active clinic surveillance started. We review all the reports of rectal Chlamydia trachomatis and LGV testing of those samples. Chlamydia trachomatis LGV DNA was detected by Nucleic Acid Amplification/ompA gene sequencing. Read More

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http://jia.sagepub.com/content/11/4/220.full.pdf
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http://jia.sagepub.com/cgi/doi/10.1177/1545109712447198
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http://dx.doi.org/10.1177/1545109712447198DOI Listing
February 2014
5 Reads

Increased adolescent HIV infection during pregnancy leads to increase in perinatal transmission at urban referral center.

J Int Assoc Physicians AIDS Care (Chic) 2012 Sep-Oct;11(5):293-5. Epub 2012 May 24.

1Division of Allergy and Immunology, Children's Hospital of Michigan, Wayne State University, Detroit, MI, USA.

Background: Undiagnosed HIV during pregnancy leads to increased perinatal infection. Four cases of adolescents/young adults with HIV contracted during pregnancy, after initial negative HIV testing, led to 4 cases of perinatal HIV, which were diagnosed only after AIDS-defining illness occurred in infants. These cases were missed despite HIV testing during pregnancy. Read More

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http://dx.doi.org/10.1177/1545109712446175DOI Listing
February 2014
3 Reads

Vanishing lung syndrome and HIV infection: an uncommon yet potentially fatal sequela of cigarette smoking.

J Int Assoc Physicians AIDS Care (Chic) 2012 Jul-Aug;11(4):230-3. Epub 2012 May 7.

1Division of Internal Medicine, Multicare Good Samaritan Medical Center, Puyallup, WA, USA.

Persons with HIV infection have a higher risk of infectious pulmonary complications, chronic obstructive pulmonary disease, lung cancer, pulmonary hypertension, and pulmonary fibrosis than individuals not infected with HIV. Herein, we describe the clinical course of a patient with longstanding and well-controlled HIV infection and multiple previous pneumothoraces who presented to medical attention with insidious onset of shortness of breath and was diagnosed with vanishing lung syndrome (VLS). The VLS or giant bullous emphysema is a distinct clinical syndrome characterized by large bullae, predominantly in the upper lobes, occupying at least one third of the hemithorax and compressing surrounding normal lung parenchyma. Read More

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http://dx.doi.org/10.1177/1545109712444755DOI Listing
February 2014
5 Reads

Provider and patient correlates of provider decisions to recommend HCV treatment to HIV co-infected patients.

J Int Assoc Physicians AIDS Care (Chic) 2012 Jul-Aug;11(4):245-51. Epub 2012 May 7.

1RAND Corporation, Santa Monica, CA, USA.

Despite low uptake of hepatitis C virus (HCV) treatment among HIV co-infected patients, few studies have examined the factors that contribute to provider decisions to recommend treatment. Surveys of 173 co-infected patients and their primary care providers, as well as patient chart data, were collected at 3 HIV clinics in Los Angeles; 73% of the patients had any history of being recommended HCV treatment. Multivariate predictors of being offered treatment included being Caucasian, greater HCV knowledge, receiving depression treatment if depressed, and one's provider having a lower weekly patient load and more years working at the study site. Read More

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http://dx.doi.org/10.1177/1545109712444163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419326PMC
February 2014
2 Reads

A giant pancreatic pseudocyst in a patient with HIV infection.

J Int Assoc Physicians AIDS Care (Chic) 2012 Jul-Aug;11(4):227-9. Epub 2012 May 2.

1Department of Infectious Diseases, "Santa Maria della Misericordia" Hospital, University of Perugia, Italy.

This article describes the first case of a giant pancreatic pseudocyst in a 48-year-old man with HIV infection under combination antiretroviral therapy. The patient presented with an abdominal mass involving the epigastrium, left hypochondrium, and left flank. An enhanced abdominal computed tomography (CT) scan showed a well-defined cyst of 21 cm in diameter, with a liquid content that dislocated adjacent viscera. Read More

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http://dx.doi.org/10.1177/1545109712444164DOI Listing
February 2014
9 Reads

Polyneuropathy associated with the diffuse infiltrative lymphocytosis syndrome.

J Int Assoc Physicians AIDS Care (Chic) 2012 Jul-Aug;11(4):223-6. Epub 2012 Apr 27.

1University of Michigan Medical School, Ann Arbor, MI, USA.

Diffuse infiltrative lymphocytosis syndrome (DILS) arises in HIV-positive patients secondary to infiltration of lymphocytes into the peripheral tissues and produces the disease's characteristic symptoms-parotid gland enlargement and a sicca syndrome. Many patients, however, first seek medical attention for treatment of the extraglandular manifestations of DILS, most commonly interstitial pneumonitis. In this case report, we describe an atypical presentation of DILS characterized by polyradiculoneuropathy in the absence of parotid gland enlargement or interstitial pneumonitis. Read More

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http://dx.doi.org/10.1177/1545109712442798DOI Listing
February 2014
3 Reads

Diarrhea associated with lopinavir/ritonavir-based therapy: results of a meta-analysis of 1469 HIV-1-infected participants.

J Int Assoc Physicians AIDS Care (Chic) 2012 Jul-Aug;11(4):252-9. Epub 2012 Apr 27.

1Abbott, Abbott Park, IL, USA.

Background: Antiretroviral therapy is associated with adverse events (AEs). The most frequently reported AE associated with lopinavir/ritonavir (LPV/r) containing regimens is diarrhea. The objective of this meta-analysis is to describe the incidence, prevalence, and duration of diarrhea in individuals taking LPV/r. Read More

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http://dx.doi.org/10.1177/1545109712442984DOI Listing
February 2014
9 Reads

Use of dual-energy x-ray absorptiometry (DXA) scans in HIV-infected patients.

J Int Assoc Physicians AIDS Care (Chic) 2012 Jul-Aug;11(4):239-44. Epub 2012 Apr 17.

1University of Maryland Medical Center, Internal Medicine, Baltimore, MD, USA.

Multiple studies have demonstrated increased rates of osteopenia and osteoporosis in HIV-infected patients but there have been no published studies on current screening practices. We conducted a retrospective chart review of 2924 patients attending an urban HIV clinic. Thirty patients (1%) had dual-energy x-ray absorptiometry (DXA) scans. Read More

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http://dx.doi.org/10.1177/1545109712438751DOI Listing
February 2014
4 Reads

Low prevalence of chronic hypertransaminasemia in a cohort of HIV-infected patients with no coinfections.

J Int Assoc Physicians AIDS Care (Chic) 2012 Mar-Apr;11(2):89-90

1Unidad de Gestión Clínica de Enfermedades Infecciosas, Hospital Virgen de la Victoria, Málaga, Spain.

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http://dx.doi.org/10.1177/1545109711427606DOI Listing
February 2014
5 Reads

Brain abscesses in HIV-positive patients due to Pneumocystis jiroveci.

J Int Assoc Physicians AIDS Care (Chic) 2012 May-Jun;11(3):169-71. Epub 2012 Mar 26.

1Internal Medicine and Infectious Diseases, Hôtel-Dieu de France Hospital, Saint-Joseph University, Beirut, Lebanon.

Cerebral toxoplasmosis is common in AIDS patients; however, pneumocystosis of the brain is rarely documented. We report a patient with AIDS hospitalized for brain abscesses. Stereotactic brain biopsy with immunofluorescence staining was positive for Pneumocystis jiroveci. Read More

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http://dx.doi.org/10.1177/1545109712439625DOI Listing
February 2014
16 Reads

HIV-related stigma, isolation, discrimination, and serostatus disclosure: a global survey of 2035 HIV-infected adults.

J Int Assoc Physicians AIDS Care (Chic) 2012 May-Jun;11(3):172-8. Epub 2012 Mar 19.

1Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

Background: Little is known globally about the perspectives of people living with HIV/AIDS (PLWHA) on perceived HIV-related stigma and its consequences.

Methods: Cross-sectional study (January-March 2010) of perceived HIV-related stigma among PLWHA (N = 2035) using a standardized questionnaire.

Findings: Thirty-seven percent of respondents reported loneliness as a result of their HIV status. Read More

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http://dx.doi.org/10.1177/1545109712436723DOI Listing
February 2014
7 Reads

HIV treatment adherence, patient health literacy, and health care provider-patient communication: results from the 2010 AIDS Treatment for Life International Survey.

J Int Assoc Physicians AIDS Care (Chic) 2012 Mar-Apr;11(2):128-33. Epub 2012 Feb 23.

1Department of Medicine and Centre for Infectious Diseases (CID), Stellenbosch University, Faculty of Health Sciences, Cape Town, South Africa.

Background: Little is known about patients' health literacy regarding antiretroviral therapy (ART) adherence and drug resistance and patient-provider communication about these topics.

Design And Methods: The AIDS Treatment for Life International Survey was a multicountry cross-sectional study (January-March 2010) including 2035 HIV-infected adults. A 40-minute interview was conducted using a standardized self-report adherence questionnaire. Read More

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http://journals.sagepub.com/doi/10.1177/1545109712437244
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http://dx.doi.org/10.1177/1545109712437244DOI Listing
February 2014
3 Reads

Mobile phone communication and health system strengthening: a pilot study of telephonic warmline consultation in HIV care and support in South India.

J Int Assoc Physicians AIDS Care (Chic) 2012 May-Jun;11(3):184-7. Epub 2012 Feb 21.

1International Training and Education Center for Health (I-TECH), Chennai, Tamil Nadu, India.

Introduction: I-TECH India established a warmline pilot in the year 2008 to provide mobile-based technical support on clinical management to doctors caring for HIV patients in antiretroviral therapy (ART) centers.

Methods: Warmline was piloted from May to August 2008. Standardized call records were analyzed. Read More

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http://dx.doi.org/10.1177/1545109711428010DOI Listing
February 2014
3 Reads

Internal medicine and emergency medicine physicians lack accurate knowledge of current CDC HIV testing recommendations and infrequently offer HIV testing.

J Int Assoc Physicians AIDS Care (Chic) 2012 Mar-Apr;11(2):101-8. Epub 2012 Feb 14.

1Department of Internal Medicine, University of Cincinnati Academic Health Center, Cincinnati, OH, USA.

Objectives: To evaluate the knowledge and attitudes of residents and attendings in emergency medicine (EM) and internal medicine (IM) about HIV.

Methods: An electronic anonymous 41-question survey of IM and EM physicians at the University of Cincinnati Academic Health Center.

Results: The survey was completed by 232 physicians (71. Read More

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http://journals.sagepub.com/doi/10.1177/1545109711430165
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http://dx.doi.org/10.1177/1545109711430165DOI Listing
February 2014
3 Reads

A potential drug-herbal interaction between Ginkgo biloba and efavirenz.

J Int Assoc Physicians AIDS Care (Chic) 2012 Mar-Apr;11(2):98-100. Epub 2012 Feb 9.

1Department of Medicine, Division of Infectious Diseases, St Michael's Hospital, Toronto, ON, Canada.

Efavirenz (EFV) is primarily metabolized by cytochrome P450 (CYP) 2B6 and to a lesser extent by CYP3A4. Drugs that significantly inhibit or induce these enzymes would then be expected to increase or lower the levels of EFV potentially resulting in toxicity or therapeutic failure, respectively. The constituents of Ginkgo biloba extract have been demonstrated to induce gene expression of the CYP450 enzymes. Read More

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http://dx.doi.org/10.1177/1545109711435364DOI Listing
February 2014
7 Reads

Factors associated with antiretroviral medication adherence among HIV-positive adults accessing highly active antiretroviral therapy (HAART) in British Columbia, Canada.

J Int Assoc Physicians AIDS Care (Chic) 2012 Mar-Apr;11(2):134-41. Epub 2012 Feb 7.

1Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.

Background: Among those accessing treatment, highly active antiretroviral therapy (HAART) has transformed HIV into a chronic and manageable condition. However, high levels of adherence are required to derive a sustained, long-term clinical benefit. The aim of this study was to examine the predictors of adherence based on prescription refill among persons on HAART in British Columbia, Canada. Read More

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http://dx.doi.org/10.1177/1545109711423976DOI Listing
February 2014
10 Reads

Characterization of HIV-associated Hodgkin's lymphoma in HIV-infected patients: a single-center experience.

J Int Assoc Physicians AIDS Care (Chic) 2012 Jul-Aug;11(4):234-8. Epub 2012 Feb 1.

1Section of Infectious Diseases and Geriatric Medicine, Department of Medicine, Louisiana State University Health Sciences Center in New Orleans, New Orleans, LA, USA.

Introduction: Although the incidence and prevalence of AIDS-defining malignancies has decreased in the era of highly active antiretroviral therapy (HAART), the incidence and prevalence of Hodgkin's lymphoma (HL) in the HIV-infected population continues to rise. Compared with the general population, HIV-infected patients exhibit a 5-10-fold increased risk for developing HL.

Methods: A retrospective review of charts and electronic records from 2000-2010 at the HIV outpatient clinic (HOP)-Louisiana State University in New Orleans was conducted, and pathologically confirmed cases of HIV-HL were identified within this cohort. Read More

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http://dx.doi.org/10.1177/1545109711431492DOI Listing
February 2014
3 Reads

Vitamin D insufficiency and deficiency among HIV-1-infected patients in a tropical setting.

J Int Assoc Physicians AIDS Care (Chic) 2012 Sep-Oct;11(5):305-10. Epub 2012 Jan 13.

1Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Vitamin D plays role in bone health and the regulation of the immune system. A cross-sectional study of serum 25-hydroxyvitamin D (25[OH]D) levels was conducted among HIV-1-infected Thai patients to determine the prevalence and associated factors of low vitamin D levels (25[OH]D <30 ng/mL) in tropical setting. 25-Hydroxyvitamin D was measured by liquid chromatography/tandem mass spectrometry. Read More

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http://dx.doi.org/10.1177/1545109711432142DOI Listing
February 2014
2 Reads

Immunologic effectiveness of maraviroc- and raltegravir-containing regimens (R+M+) versus raltegravir-based regimens that do not include maraviroc (R+M-).

J Int Assoc Physicians AIDS Care (Chic) 2012 May-Jun;11(3):192-7. Epub 2012 Jan 13.

1University of Toronto, Toronto, Ontario, Canada.

Objective: To compare the immunologic effectiveness of raltegravir-maraviroc (R+M+)-based regimens with raltegravir-based regimens that do not include maraviroc (R+M-) in treatment-experienced patients in clinical practice.

Methods: We conducted a retrospective study of treatment-experienced HIV-infected adults receiving either R+M+- or R+M--based therapy. Longitudinal CD4 counts were analyzed using a linear mixed model. Read More

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http://journals.sagepub.com/doi/10.1177/1545109711424967
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http://dx.doi.org/10.1177/1545109711424967DOI Listing
February 2014
6 Reads

Preferences for rapid point-of-care HIV testing in primary care.

J Int Assoc Physicians AIDS Care (Chic) 2012 May-Jun;11(3):157-63. Epub 2012 Jan 13.

1Public Health and Preventive Medicine Residency Program, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.

Although the identification of individuals infected with HIV is an important element of treatment and prevention programs, many people living with HIV are unaware of their status. Thus, individuals are unable to benefit from treatment, and preventable HIV transmission continues to occur. Rapid point-of-care testing for HIV has been found to be preferred by patients in some contexts. Read More

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http://dx.doi.org/10.1177/1545109711427605DOI Listing
February 2014
4 Reads

Sequential antiretroviral adherence measurement using electronic bottle cap monitors in a cohort of HIV-infected adults.

J Int Assoc Physicians AIDS Care (Chic) 2012 Mar-Apr;11(2):94-7. Epub 2012 Jan 5.

1AIDS Center and Division of Infectious Diseases, Montefiore Medical Center, Bronx, NY, USA.

Most studies employing electronic bottle monitors to measure antiretroviral adherence are limited to 24 weeks of duration, providing a snapshot of adherence from a treatment course that may be lifelong. The stability of these measures in individual patients over time has not been previously described. We measured antiretroviral adherence using Medication Event Monitoring System (MEMS) caps in a patient cohort in 2004 and 2005 and repeated the measurement in 2008 and 2009. Read More

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http://dx.doi.org/10.1177/1545109711420498DOI Listing
February 2014
2 Reads

Coronary Events in HIV-Infected Patients.

J Int Assoc Physicians AIDS Care (Chic) 2011 Nov-Dec;10(6):337-8

1Unidad de Gestión Clínica de Enfermedades Infecciosas, Hospital Virgen de la Victoria, Málaga, Spain.

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http://dx.doi.org/10.1177/1545109711423072DOI Listing
April 2016
14 Reads

Introduction to Special Section on HIV/AIDS and Substance Use in the Caribbean (Part 2): The Influence of Mobility and Environmental Conditions.

J Int Assoc Physicians AIDS Care (Chic) 2011 Sep-Oct;10(5):303-5

1Department of Health Promotion and Disease Prevention, AIDS Prevention Program, Stempel College of Public Health & Social Work, Florida International University, Miami, FL, USA.

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http://dx.doi.org/10.1177/1545109711424875DOI Listing
April 2016
4 Reads

Nevirapine-associated hepatotoxicity and rash among HIV-infected pregnant women in Kenya.

J Int Assoc Physicians AIDS Care (Chic) 2012 Mar-Apr;11(2):142-9. Epub 2011 Oct 21.

1Centers for Disease Control and Prevention, Atlanta, GA, USA.

Background: Few studies have evaluated the risk of nevirapine (NVP)-associated hepatotoxicity among HIV-infected pregnant women with a CD4 count ≥250 cells/mm(3).

Methods: We enrolled HIV-infected pregnant Kenyan women who initiated triple antiretroviral therapy (ART) at 34 weeks gestation. We compared the rates of severe hepatotoxicity (grades 3-4 hepatotoxicity) and rash-associated hepatotoxicity (rash with ≥grade 2 hepatotoxicity) with NVP and nelfinavir (NFV), respectively. Read More

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http://dx.doi.org/10.1177/1545109711423445DOI Listing
February 2014
8 Reads

Resistance-associated mutations in HIV-1 among patients failing first-line antiretroviral therapy.

J Int Assoc Physicians AIDS Care (Chic) 2012 May-Jun;11(3):203-9. Epub 2011 Oct 11.

1Department of Microbiology, Maulana Azad Medical College and Associated Lok Nayak Hospital, New Delhi, India.

Thirty-five HIV-1 infected patients showing clinical and/or immunological failure to first line antiretroviral therapy (ART) according to WHO criteria were recruited from the ART center of Lok Nayak Hospital, New Delhi to detect the presence of resistance-mutations in reverse transcriptase (RT) and protease (PR) region of pol gene of HIV-1. Plasma viral load (PVL) was estimated. HIV-1 pol gene region encoding complete protease and reverse transcriptase (codons; 1-232 to 1-242) was reverse transcribed, followed by nested PCR. Read More

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http://dx.doi.org/10.1177/1545109711421217DOI Listing
February 2014
2 Reads

The Achilles' Heel of HIV Treatment for Prevention: History of Sexually Transmitted Coinfections among People Living with HIV/AIDS Receiving Antiretroviral Therapies.

J Int Assoc Physicians AIDS Care (Chic) 2011 Nov-Dec;10(6):365-72. Epub 2011 Oct 11.

1Department of Psychology, University of Connecticut, Storrs, CT, USA.

Background: Antiretroviral therapies (ARTs) offer promising new avenues for HIV prevention. Unfortunately, people infected with HIV who have co-occurring sexually transmitted infections (STIs) are more infectious than suggested by the amount of virus in their peripheral blood. We examined the history of sexually transmitted coinfections in people living with HIV. Read More

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http://dx.doi.org/10.1177/1545109711418120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286333PMC
April 2016
2 Reads

Further evidence that the expression of CD38 and HLA-DR(+) in CD8(+) lymphocytes does not correlate to disease progression in HIV-1 vertically infected children.

J Int Assoc Physicians AIDS Care (Chic) 2012 May-Jun;11(3):164-8. Epub 2011 Oct 5.

1Postgraduate Pathology Program, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.

Background: In adults, an increase in CD8(+)CD38(+) T cell levels is a strong indicator of disease progression in HIV infection. However, in children, data are conflicting. Slow-progressing children (SPC) provide an exceptional resource for the investigation and clarification of the immunological and virological mechanisms of natural control of HIV infection and can be used to investigate prognostic indicators of disease progression. Read More

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http://dx.doi.org/10.1177/1545109711421642DOI Listing
February 2014
10 Reads

Reverse transcriptase genotypes in pediatric patients failing initial antiretroviral therapy in Gaborone, Botswana.

J Int Assoc Physicians AIDS Care (Chic) 2012 Jul-Aug;11(4):260-8. Epub 2011 Oct 4.

1Botswana-Baylor Children's Clinical Centre of Excellence, Gaborone, Botswana.

Background: Limited data are available on patterns of resistance mutations in pediatric patients in southern Africa, where HIV-1 subtype C (HIV-1C) predominates.

Methods: Retrospective chart review of pediatric patients. Nucleoside reverse transcriptase inhibitor (NRTI)- and nonnucleoside reverse transcriptase inhibitor (NNRTI)-associated resistance mutations quantified from population-based sequencing genotypic resistance assay results taken at time of first-line antiretroviral therapy (ART) failure (first-line ART = stavudine [d4T] or zidovudine [ZDV] + lamivudine [3TC] + nevirapine [NVP] or efavirenz [EFV]). Read More

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http://dx.doi.org/10.1177/1545109711422273DOI Listing
February 2014
3 Reads

Adherence and preexisting major protease inhibitor resistance mutations are associated with virologic failure of a dual-class antiretroviral regimen with inhibitors of HIV-1 viral protease and integrase.

J Int Assoc Physicians AIDS Care (Chic) 2012 Jan-Feb;11(1):34-9. Epub 2011 Oct 4.

1Denver Public Health, Denver, CO, USA.

Objectives: Novel treatment strategies are needed for treatment-experienced HIV-infected individuals. We retrospectively evaluated virologic outcomes on a dual-class, protease inhibitor (PI) plus raltegravir, antiretroviral (ARV) regimen.

Methods: Virologic success was defined by a plasma HIV-RNA level ≤200 copies/mL. Read More

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http://jia.sagepub.com/content/11/1/34.full.pdf
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http://jia.sagepub.com/cgi/doi/10.1177/1545109711422124
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http://dx.doi.org/10.1177/1545109711422124DOI Listing
February 2014
4 Reads

Poorer ART outcomes with increasing age at a large public sector HIV clinic in Johannesburg, South Africa.

J Int Assoc Physicians AIDS Care (Chic) 2012 Jan-Feb;11(1):57-65. Epub 2011 Sep 27.

1Department of Medicine, Clinical HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa.

Background: As the current HIV-positive population ages, the absolute number of patients >50 years on treatment is increasing.

Methods: We analyze the differences in treatment outcomes by age category (18-29, 30-39, 40-49, 50-59, and ≥ 60) among 9139 HIV-positive adults initiating ART in South Africa.

Results: The adjusted hazard ratios (HRs) for all-cause mortality increased with increasing age, with the strongest association in the first 12 months of follow-up among patients 50 to 59 years (HR 1. Read More

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http://dx.doi.org/10.1177/1545109711421641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272319PMC
February 2014
5 Reads

AIDS-related Kaposi's sarcoma can occur during peginterferon-α and ribavirin therapy for chronic hepatitis C infection.

J Int Assoc Physicians AIDS Care (Chic) 2012 Jan-Feb;11(1):9-11. Epub 2011 Sep 20.

1Infectious Diseases Department, Assistance-Publique Hôpitaux de Paris (APHP), Hôpital Saint-Louis, Paris, France.

Introduction: Before the arrival of highly active antiretroviral therapy (HAART), interferon α has been used successfully to treat AIDS-related Kaposi's sarcoma (KS). Peginterferon-α (pegIFN-α) may still be used successfully in refractory KS.

Case: Peginterferon-α and ribavirin (RBV) were initiated to treat hepatitis C virus (HCV) infection in an HIV-infected patient with high CD4 counts having discontinued antiretroviral therapy (ART). Read More

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http://dx.doi.org/10.1177/1545109711420875DOI Listing
February 2014
8 Reads

HIV Risk Behavior among Youth in the Dominican Republic: The Role of Alcohol and Other Drugs.

J Int Assoc Physicians AIDS Care (Chic) 2011 Nov-Dec;10(6):388-95. Epub 2011 Sep 12.

1Silver School of Social Work, New York University, New York, NY, USA.

Existing literature related to HIV in the Dominican Republic has tended to neglect the unique role of tourism areas as distinct ecologies facilitative of sexual risk behavior, particularly HIV vulnerability and transmission. Furthermore, limited attention has focused on Dominican adolescents living in close proximity to tourism areas who have become increasingly exposed to alcohol due to the expanding tourism industry in the Dominican Republic. While most previous analyses of the effects of alcohol on adolescent sexual risk behavior have focused on the transient effects of alcohol on judgment and decision making, the effects of chronic alcohol use on sexual behavior has been a neglected area of research. Read More

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http://dx.doi.org/10.1177/1545109711419264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319024PMC
April 2016
4 Reads

Antiretroviral therapy initiation in France: adherence to national guidelines and outcome.

J Int Assoc Physicians AIDS Care (Chic) 2012 Jan-Feb;11(1):40-6. Epub 2011 Aug 31.

1Department of Infectious Diseases, Saint Louis Hospital, AH-HP, and University of Paris Diderot, Paris, France.

Objectives And Methods: Retrospective study of all patients who started antiretroviral therapy (ART) in 2007 in a single center in Paris, with baseline characteristics and 1-year outcome, to assess adherence to national guidelines.

Results: We analyzed 118 patients. Time of ART initiation was in agreement with the guidelines for only 64 (54. Read More

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http://dx.doi.org/10.1177/1545109711418362DOI Listing
February 2014
3 Reads

How the Illicit Drug Economy Contributes to HIV Risk in St Vincent and the Grenadines.

J Int Assoc Physicians AIDS Care (Chic) 2011 Nov-Dec;10(6):396-406. Epub 2011 Aug 29.

1Center for AIDS Prevention Studies, University of California, San Francisco, CA, USA.

St Vincent and the Grenadines (SVG) is the largest marijuana producer in the Eastern Caribbean. As the European Union has phased out preferred access for its banana crop, marijuana has become one of the main sources of income and a safety net for many young men, in particular. HIV is a problem for youth in SVG where 60% of the population and 50% of cumulative AIDS cases are among individuals under 30 years of age. Read More

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http://dx.doi.org/10.1177/1545109711418508DOI Listing
April 2016
10 Reads