2,142 results match your criteria Journal of the Chinese Medical Association : JCMA[Journal]


Accuracy of implant placement with a computer-aided fabricated surgical template with guided parallel pins: A pilot study.

J Chin Med Assoc 2018 Nov 30;81(11):970-976. Epub 2018 Jun 30.

Division of Oral and Maxillofacial Surgery, Department of Dentistry, Chang Bing Show Chan Memorial Hospital, Changhwa, Taiwan, ROC; School of Dentistry, National Yang-Ming University, Taipei, Taiwan, ROC. Electronic address:

Background: A precise positioning for dental implant placement is important for further prosthesis fabrication and maintenance. Computer-aided surgery has been developed to transfer digitally planned implant positioning to the patient over the past decades. This study aimed to evaluate the accuracy of a computer-aided laboratory-fabricated surgical template. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17264901183016
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http://dx.doi.org/10.1016/j.jcma.2018.04.004DOI Listing
November 2018
5 Reads

Assisted reproductive technology and adverse pregnancy outcome- focus on maternal death.

J Chin Med Assoc 2018 Nov;81(11):933-934

Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; Department of Obstetrics and Gynecology, National Yang-Ming University, Taipei, Taiwan, ROC; Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan, ROC; Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, ROC. Electronic address:

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http://dx.doi.org/10.1016/j.jcma.2018.09.001DOI Listing
November 2018

Agreement of post-LASIK corneal power and corneal thickness measurements by pentacam and GALILEI corneal tomography systems.

J Chin Med Assoc 2018 Sep 26. Epub 2018 Sep 26.

Department of Ophthalmology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC. Electronic address:

Background: Post-LASIK corneal conditions cannot be accurately measured by traditional optometric approaches. Therefore, we aimed to analyze the agreement of two rotating Scheimpflug cameras in corneal assessment.

Methods: Fifty otherwise healthy volunteers who had undergone LASIK were recruited in this study. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.07.005DOI Listing
September 2018

Impact of hypoxic and mesopic environments on visual acuity, contrast sensitivity and accommodation in subjects with LASIK surgery and aircrew candidate.

J Chin Med Assoc 2018 Nov 15;81(11):998-1007. Epub 2018 Sep 15.

Department of Ophthalmology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC; Graduate Institute of Aerospace and Undersea Medicine, National Defense Medical Center, Taipei, Taiwan, ROC. Electronic address:

Background: The safety of Laser-assisted in situ keratomileusis (LASIK) in aircrew was unclear, in addition, LASIK was not yet approved for aircrew of Taiwan Air Force. This study was aimed to evaluate visual performance in LASIK eyes in hypoxic and twilight environment.

Methods: 48 myopic eyes of 24 subjects enrolled in this study were divided into LASIK group and control group. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.04.009DOI Listing
November 2018
1 Read

Reply.

J Chin Med Assoc 2018 Nov 7;81(11):1015. Epub 2018 Sep 7.

Güven Hospital, Pathology Department, Ankara, Turkey.

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http://dx.doi.org/10.1016/j.jcma.2018.07.003DOI Listing
November 2018
1 Read

Huperzine-A response to cognitive impairment and task switching deficits in patients with Alzheimer's disease.

J Chin Med Assoc 2018 Sep 7. Epub 2018 Sep 7.

Department of Applied Psychology, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.

Background: Alzheimer's Disease (AD) is associated with cognitive decline due to various pathological mechanisms. There are several acetylcholinesterase inhibitor compounds which can improve cognition, but Huperzine-A is a natural sesquiterpene alkaloid extracted from Chinese herb (Huperzia Serrata) which has rapid action.

Methods: Double blind study was conducted. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.07.004DOI Listing
September 2018

Correlation between lower uterine wall thickness measured by transabdominal ultrasonography and cervical length measured by transvaginal ultrasonography in Thai pregnant women.

J Chin Med Assoc 2018 Sep 7. Epub 2018 Sep 7.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Background: Preterm labor is one of major obstetric challenges and can be predicted by cervical length at mid-trimester. In some settings, transvaginal ultrasound is not available and the screening and prevention of preterm labor will be suboptimal. We hope to find a correlation between other marker i. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17264901183022
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http://dx.doi.org/10.1016/j.jcma.2018.07.006DOI Listing
September 2018
9 Reads

Does continued aspirin mono-therapy lead to a higher bleeding risk after total knee arthroplasty?

J Chin Med Assoc 2018 Sep 7. Epub 2018 Sep 7.

Department of Orthopaedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; Department of Orthopaedics, School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC. Electronic address:

Background: Evidence about the risk of bleeding and thromboembolism because of aspirin mono-therapy in total knee arthroplasty (TKA) is scant. We wanted to validate the risks of bleeding and thromboembolism with continued aspirin mono-therapy in unilateral and simultaneous bilateral TKA.

Methods: We enrolled a series of 1655 patients who underwent unilateral or simultaneous bilateral TKA between December 2010 and December 2012. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17264901183022
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http://dx.doi.org/10.1016/j.jcma.2018.08.002DOI Listing
September 2018
6 Reads

Fertility-enhancing agents.

J Chin Med Assoc 2018 Nov 7;81(11):1013-1014. Epub 2018 Sep 7.

Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; Department of Obstetrics and Gynecology, National Yang-Ming University, Taipei, Taiwan, ROC; Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan, ROC; Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, ROC. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S17264901183022
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http://dx.doi.org/10.1016/j.jcma.2018.08.001DOI Listing
November 2018
3 Reads

Effect of ivabradine, a funny current inhibitor, on portal hypertensive rats.

J Chin Med Assoc 2018 Sep 6. Epub 2018 Sep 6.

Faculty of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC; Cheng-Hsin General Hospital, Taipei, Taiwan, ROC.

Background: Ivabradine is a funny current inhibitor which is administered to patients with congestive heart failure to reduce their heart rate (HR) and attenuate oxidative stress. Chronic liver diseases are characterized by portal hypertension and hyperdynamic circulation with tachycardia. The present study aimed to investigate the effect of ivabradine on portal hypertension. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.06.008DOI Listing
September 2018
14 Reads

Impact of code stroke on thrombolytic therapy in patients with acute ischemic stroke at a secondary referral hospital in Taiwan.

J Chin Med Assoc 2018 Nov 7;81(11):942-948. Epub 2018 Sep 7.

Stroke Center and Department of Neurology, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan, ROC; School of Medicine, Tzu Chi University, Hualien, Taiwan, ROC. Electronic address:

Background: Efficacy of thrombolytic therapy decreases with time elapsed from symptom onset. We sought to identify the impact of code stroke on the thrombolytic therapy.

Methods: Code stroke is activated by the emergency physician when a patient is eligible for thrombolytic therapy. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.06.007DOI Listing
November 2018
2 Reads

The use of time-domain analysis on the choice of measurement location for pulse diagnosis research: A pilot study.

J Chin Med Assoc 2018 Sep 6. Epub 2018 Sep 6.

Graduate Institute of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan, ROC; National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei, Taiwan, ROC; School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan, ROC. Electronic address:

Background: Pulse diagnosis researches acquiring pulse waves from the wrist radial artery has not yet addressed the issue of whether this information is affected by differences in the hemodynamic characteristics of pressure waves derived from different locations. This study aimed to clarify whether the blood dynamic states are identical with regard to the "three positions and nine indicators" () listed in traditional Chinese medicine (TCM).

Methods: A total of 37 participants of CAD group and 20 participants of healthy group were recruited, and pressure pulse waves were measured at 18 locations on both hands. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17264901183020
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http://dx.doi.org/10.1016/j.jcma.2018.07.002DOI Listing
September 2018
5 Reads

Can imaging distinguish between low-grade and dedifferentiated parosteal osteosarcoma?

J Chin Med Assoc 2018 Oct 3;81(10):912-919. Epub 2018 Sep 3.

Department of Radiology, Taipei Veterans General Hospital, School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC.

Background: Most instances of the parosteal osteosarcoma (OGS) are low-grade tumors. However, some parosteal OGSs undergo dedifferentiated transformation. Dedifferentiated parosteal OGS can cause distant metastasis and poor survival, and preoperative chemotherapy may be warranted. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.01.014DOI Listing
October 2018

Situation of seven-day service among family medicine clinics in Taiwan: A nationwide survey.

J Chin Med Assoc 2018 Nov 1;81(11):964-969. Epub 2018 Sep 1.

Department of Family Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC. Electronic address:

Background: General medicine practices in England are required to provide services from 8am to 8pm on weekdays and to also open on Saturdays and Sundays. Internationally, however, the literature regarding the temporal availability of primary health care on national levels is scarce.

Methods: To provide such information regarding Taiwan, in this study, all family medicine clinics within Taiwan's National Health Insurance system were stratified by urbanization level, and the opening hours of the clinics were then analyzed. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17264901183019
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http://dx.doi.org/10.1016/j.jcma.2017.12.010DOI Listing
November 2018
5 Reads
0.890 Impact Factor

Is low serum level of vitamin D risky for increased pulmonary morbidities in extremely immature newborns?

J Chin Med Assoc 2018 Sep 28;81(9):848-849. Epub 2018 Jun 28.

Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; Department of Obstetrics and Gynecology, National Yang-Ming University, Taipei, Taiwan, ROC; Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan, ROC; Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, ROC. Electronic address:

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http://dx.doi.org/10.1016/j.jcma.2018.06.001DOI Listing
September 2018

Long-term results of palatal implantation for severe obstructive sleep apnea patients with prominent retropalatal collapse.

J Chin Med Assoc 2018 Sep 6;81(9):837-841. Epub 2018 Jul 6.

Department of Otolaryngology, Cheng Hsin General Hospital, Taipei, Taiwan, ROC; Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC. Electronic address:

Background: Most previous reports on palatal implantation for patients with severe obstructive sleep apnea have been anecdotal. Our objective in this study was to assess the long-term outcomes of palatal implantations from objective as well as subjective perspectives when applied to patients with severe obstructive sleep apnea and prominent retropalatal collapse.

Methods: This retrospective review was conducted in a single institution using subjective data (Epworth Sleepiness Scale and visual analog scales of snoring sounds and sleep quality) and objective data (respiratory disturbance index, minimum O saturation, sleep efficiency, and snoring index using a polysomnograph) before and after surgery. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17264901183015
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http://dx.doi.org/10.1016/j.jcma.2018.01.012DOI Listing
September 2018
8 Reads
0.890 Impact Factor

Comparing recommended sanctions for lapses of academic integrity as measured by Dundee Polyprofessionalism Inventory I: Academic integrity from a Saudi and a UK medical school.

J Chin Med Assoc 2018 Sep 2;81(9):787-795. Epub 2018 Jul 2.

Vice Dean College of Medicine, Clinical Sciences Department, University of Sharjah United Arab Emirates. Electronic address:

Background: There are varying perceptions about professionalism and academic integrity, both being influenced by regional, cultural, contextual and religious factors worldwide. Very few studies have compared the variations in understanding about academic integrity among medical faculty and students. This study explored the existing understanding of academic integrity in a Saudi and a UK medical school. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.04.001DOI Listing
September 2018

Renal transplantation delays major adverse cardiac events (MACEs) in patients with end-stage renal disease: A nationwide population-based study.

J Chin Med Assoc 2018 Sep 30;81(9):766-771. Epub 2018 Jun 30.

Faculty of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC; Division of Nephrology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC. Electronic address:

Background: Whether renal transplantation (RT) influences the risk of cardiovascular events remains controversial.

Methods: This nationwide population-based study investigated the risk of major adverse cardiac events (MACEs) and stroke after RT in patients with end-stage renal disease (ESRD), using data obtained from the National Health Insurance Research Database in Taiwan. A total of 164 ESRD patients who underwent RT formed the study cohort, and an age- and sex-matched control group comprised 164 patients without RT selected from 6976 ESRD patients. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.04.003DOI Listing
September 2018

Evaluating cerebral hemodynamics using quantitative digital subtraction angiography and flat-detector computed tomography perfusion imaging: A comparative study in patients with carotid stenosis.

J Chin Med Assoc 2018 Nov 23;81(11):977-984. Epub 2018 Aug 23.

Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC.

Background: The efficacy of both quantitative digital subtraction angiography (QDSA) and flat-detector computed tomography perfusion (FD-CTP) is equivalent to that of magnetic resonance perfusion (MRP) in assessing perfusion deficits in carotid stenosis. This study evaluated the feasibility of using FD-CTP to monitor cerebral hemodynamics during carotid stenting.

Methods: Thirteen patients with extracranial carotid stenosis (>70%) were included. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.01.016DOI Listing
November 2018

Evaluation of peripheral blood NK cell subsets and cytokines in unexplained recurrent miscarriage.

J Chin Med Assoc 2018 Dec 23;81(12):1065-1070. Epub 2018 Aug 23.

Pathologist, Razi Pathobiology Lab, Babol, Iran.

Background: Recurrent miscarriage is considered as one of the main problems in women's reproductive health. The aim of the present study was to evaluate the natural killer cells (NK cells) and cytokines in unexplained recurrent miscarriage and fertile women.

Methods: In this case-control study, 40 women with unexplained recurrent miscarriage were assigned to the case group and 40 fertile women were assigned to the control group. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.05.005DOI Listing
December 2018
0.890 Impact Factor

Correlations between serum hepatitis B surface antigen and hepatitis B core antibody titers and liver fibrosis in treatment-naïve CHB patients.

J Chin Med Assoc 2018 Dec 22;81(12):1052-1059. Epub 2018 Aug 22.

Division of Liver Disease, The Fifth Hospital of Shijiazhuang, Hebei Medical University, Shijiazhuang, Hebei, China. Electronic address:

Background: Previous studies have revealed that quantitative hepatitis B surface antigen (HBsAg) or hepatitis B core antibody (qAnti-HBc) levels can be used as predictors of treatment response in both interferon-α and nucleoside analogue therapies. Few data have been published regarding the relationship between quantitative HBsAg or Anti-HBc levels and liver fibrosis stages in patients with chronic hepatitis B (CHB).

Methods: We conducted a cross-sectional study of treatment-naïve CHB patients. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.05.007DOI Listing
December 2018
8 Reads

ALBI grade as a new player in hepatocellular carcinoma.

Authors:
Teh-Ia Huo

J Chin Med Assoc 2018 Aug 20. Epub 2018 Aug 20.

Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; Faculty of Medicine, Institute of Pharmacology, National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC. Electronic address:

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http://dx.doi.org/10.1016/j.jcma.2018.07.001DOI Listing
August 2018
7 Reads

Baicalein attenuates neuropathic pain and improves sciatic nerve function recovery in rats with partial sciatic nerve transection.

J Chin Med Assoc 2018 Nov 20;81(11):955-963. Epub 2018 Aug 20.

Department of Anesthesiology, National Defense Medical Center and Tri-Service General Hospital, Taipei, Taiwan, ROC. Electronic address:

Background: Modulating the inflammatory response to nerve injury may provide therapeutic opportunities by aborting the neurobiological alterations that support the development of persistent pain. Baicalein, a 12-lipoxygenase inhibitor, has anti-inflammation properties. It also demonstrates anti-inflammatory functions by inhibiting lipopolysaccharide-induced barrier disruption, expression of cell adhesion molecules, and adhesion and migration of leukocytes. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.03.014DOI Listing
November 2018

The effect of inhaled salbutamol on the outcomes of transient tachypnea of the newborn.

J Chin Med Assoc 2018 Nov 18;81(11):990-997. Epub 2018 Aug 18.

Department of Paediatrics, Imam Khomeini Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Background: Transient tachypnea of the newborn (TTN) is a self-limiting disease that results from a reduction in the rate of lung fluid clearance in neonates. A delay in lung fluid absorption in neonates disrupts the transition from intrauterine to extrauterine life. Use of beta-adrenergic antagonists, such as salbutamol, accelerates lung fluid clearance. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17264901183019
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http://dx.doi.org/10.1016/j.jcma.2018.01.015DOI Listing
November 2018
11 Reads

Patient response prediction with logistic regression in gastrointestinal endoscopy under midazolam-alfentanil sedation performed as well as response surface model.

J Chin Med Assoc 2018 Dec 18;81(12):1071-1076. Epub 2018 Aug 18.

Department of Anesthesiology, Taipei Veterans General Hospital and National Yang-Ming University, Taipei, Taiwan, ROC.

Background: Researchers have used logistic regression (LR) and non-linear response surface models (RSMs) to predict patient responses to sedation. The reduced Greco and hierarchy RSMs have proven to be more appropriate than other RSMs in gastrointestinal endoscopies using midazolam and alfentanil. In this study, we evaluate the performance of a simpler model, LR, and compared it with that of RSM. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.03.015DOI Listing
December 2018

A view of maternal mortalities in women conceiving through assisted reproductive techniques: A nation-based study of Turkey.

J Chin Med Assoc 2018 Nov 11;81(11):985-989. Epub 2018 Aug 11.

Turkish Public Health Agency, Preliminary Investigation Committee for Maternal Deaths, Ministry of Health, Ankara, Turkey.

Background: Our aim was to evaluate maternal mortality causes among Turkish women giving birth after assisted reproductive techniques (ARTs).

Methods: All maternal deaths following conception with ART pregnancies were identified through the National Maternal Mortality Surveillance System. We analyzed the system data collected between 2007 and 2014. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17264901183019
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http://dx.doi.org/10.1016/j.jcma.2018.05.006DOI Listing
November 2018
7 Reads
0.890 Impact Factor

Comparison of cancer detection between 18- and 12-core prostate biopsy in Asian patients with prostate-specific antigen levels of 4-20 ng/mL.

J Chin Med Assoc 2018 Dec 9;81(12):1044-1051. Epub 2018 Aug 9.

Division of Urology, Department of Surgery, Tung's Taichung MetroHarbor Hospital, Taichung, Taiwan, ROC. Electronic address:

Background: Although prostate biopsy is an accepted option for cancer detection, there is little data regarding the clinical outcome of 18-core transrectal ultrasound (TRUS)-guided biopsy. This retrospective study compared cancer detection rates and biopsy complications between 12- and 18-core TRUS biopsy in Asian patients with prostate-specific antigen (PSA) levels between 4.0 and 20. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.06.003DOI Listing
December 2018
6 Reads

Perception of fetal movement in the pregnant women.

J Chin Med Assoc 2018 Oct 9;81(10):930-931. Epub 2018 Aug 9.

Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; Department of Obstetrics and Gynecology, National Yang-Ming University, Taipei, Taiwan, ROC; Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan, ROC; Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, ROC. Electronic address:

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http://dx.doi.org/10.1016/j.jcma.2018.06.004DOI Listing
October 2018
1 Read

Early achievement of full donor chimerism after allogeneic hematopoietic stem cell transplantation predicts lower relapse risk in patients with acute lymphoblastic leukemia.

J Chin Med Assoc 2018 Dec 9;81(12):1038-1043. Epub 2018 Aug 9.

Division of Hematology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC. Electronic address:

Background: Acute lymphoblastic leukemia (ALL) remains one of the most difficult-to-cure hematological malignancies. Allogeneic hematopoietic stem cell transplantation (HSCT) provides curative potential but a substantial proportion of patients eventually will relapse. It is unknown if there are any modifiable factors exists that could improve survival or predict relapse immediately after HSCT is unknown. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.06.005DOI Listing
December 2018
1 Read

Histological study of the protective role of ginger on piroxicam-induced liver toxicity in mice.

J Chin Med Assoc 2018 Aug 9. Epub 2018 Aug 9.

Department of Anatomy, Faculty of Medicine, Northern Borders University, Saudi Arabia. Electronic address:

Background: Piroxicam is a non-steroidal anti-inflammatory drug widely used in rheumatic diseases. It has analgesic and antipyretic activity, and is one of the drugs being introduced in clinical practice. Piroxicam-hepatotoxicity has been reported as one of its principal side effects. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17264901183020
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http://dx.doi.org/10.1016/j.jcma.2018.06.006DOI Listing
August 2018
6 Reads

Hyperglycemia crisis in head and neck cancer patients with platinum-based chemotherapy.

J Chin Med Assoc 2018 Dec 9;81(12):1060-1064. Epub 2018 Aug 9.

Department of Otolaryngology, Head and Neck Surgery, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ROC; School of Medicine, National Defense Medical Center, Taipei, Taiwan, ROC; Department of Otolaryngology, Head and Neck Surgery, Tri-Service General Hospital, Taipei, Taiwan, ROC. Electronic address:

Background: The development of a hyperglycemic crisis in platinum-based chemotherapy-treated head and neck cancer patients, such as hyperosmolar hyperglycemic state (HHS), has been reported. Hyperglycemic crises are associated with a high risk of comorbidity and may delay cancer treatment if not promptly managed.

Methods: This is a retrospective study using cancer registry data from a tertiary medical center. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.05.008DOI Listing
December 2018
8 Reads

Ginger (zingiber officinale) might improve female fertility: A rat model.

J Chin Med Assoc 2018 Oct 7;81(10):905-911. Epub 2018 Aug 7.

Güven Hospital, Pathology Department, Ankara, Turkey.

Background: Ginger (Zingiber officinale) is a well known and extensively used antioxidant in traditional remedies. In this study, we aimed to investigate the effects of ginger powder on ovarian folliculogenesis and implantation in rats.

Methods: There were two study groups. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17264901183016
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http://dx.doi.org/10.1016/j.jcma.2017.12.009DOI Listing
October 2018
6 Reads

Early neurological deterioration in acute ischemic stroke: A propensity score analysis.

J Chin Med Assoc 2018 Oct 7;81(10):865-870. Epub 2018 Aug 7.

Department of Neurology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, China. Electronic address:

Background: To investigate whether endovascular therapy (EVT) was one of the factors influencing the incidence of early neurological deterioration (END) in patients with acute ischemic stroke (AIS) as compared with intravenous thrombolysis alone.

Methods: This study was based on our single-center's database that included information on stroke patients hospitalised between January 2012 and September 2015. A total of 220 patients who underwent EVT after IV rt-PA, EVT or IV rt-PA alone. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.03.011DOI Listing
October 2018
2 Reads

Clear cell papillary renal cell carcinoma - An indolent subtype of renal tumor.

J Chin Med Assoc 2018 Oct 20;81(10):878-883. Epub 2018 Jul 20.

Department of Urology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; Department of Urology, School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC; Shu-Tien Urological Science Research Center, Taipei, Taiwan, ROC. Electronic address:

Background: Clear cell papillary renal cell carcinoma (CCPRCC) is a new but rare tumor entity as listed in the World Health Organization 2016 renal tumor classification. Around 360 cases have been reported in the English literature to date, and only one tumor with sarcomatoid change was reported to develop distant metastasis. In the present study, we aim to review the clinical course and analyze the treatment outcome of CCPRCC in our institution. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.04.005DOI Listing
October 2018

Involvement of S100A4/Mts1 and associated proteins in the protective effect of fluoxetine against MCT - Induced pulmonary hypertension in rats.

J Chin Med Assoc 2018 Dec 19;81(12):1077-1087. Epub 2018 Jul 19.

Department of Clinical Pharmacology, School of Pharmacy, The First Affiliated Hospital, China Medical University, Shenyang, China; National Key Laboratory, Institute of Respiratory Diseases, The First Affiliated Hospital, China Medical University, Shenyang, China. Electronic address:

Background: Pulmonary arterial hypertension (PAH) is a complex pulmonary vasculature disease characterized by remodeling of the pulmonary vessels and a persistent increase in the pulmonary vascular resistance (PVR) with a poor prognosis. Serotonin increases the expression of S100A4/Mts1, which in turn stimulates the proliferation and migration of human pulmonary artery smooth muscle cells through the interaction with RAGE (receptor for advanced glycation end products) and thus S100A4/Mts1 has been implicated in the development of PAH in vitro. Fluoxetine, a selective serotonin re-uptake inhibitor has been shown to protect against PAH. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.03.013DOI Listing
December 2018
2 Reads

Nebulized salbutamol diminish the blood glucose fluctuation in the treatment of non-oliguric hyperkalemia of premature infants.

J Chin Med Assoc 2018 Jul 19. Epub 2018 Jul 19.

Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan, ROC; Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, Taiwan, ROC. Electronic address:

Background: Hyperkalemia is a risky and potentially life-threatening condition in pre-term infants. Glucose-insulin infusion has been considered a major therapeutic way for non-oligouric hyperkalemia but affects the stability of blood sugar level. We aimed to evaluate the effectiveness of salbutamol nebulization compared to glucose-insulin infusion for the treatment of non-oliguric hyperkalemia in premature infants. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.04.002DOI Listing
July 2018
1 Read

Generation of high quality of hepatocyte-like cells from induced pluripotent stem cells with Parp1 but lacking c-Myc.

J Chin Med Assoc 2018 Oct 13;81(10):871-877. Epub 2018 Jul 13.

Division of Gastroenterology, Department of Internal Medicine, Cheng-Hsin General Hospital, Taipei, Taiwan, ROC; School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC. Electronic address:

Background: Induced pluripotent stem cells (iPSCs) have a great potential for application in patient-specific therapy. The reprogramming method that does not involve c-Myc reduces tumorigenic risk, but also largely reduces the efficiency of generation of iPSCs, especially for those reprogrammed from damaged cells. Poly(ADP-ribose) polymerase 1 (Parp1) catalyzes a reaction of poly(ADP-ribosylation) and has been reported to enhance cell reprogramming. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.06.002DOI Listing
October 2018
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The Shipai cohort for cardiovascular metabolic risk factors and outcome study - Design and preliminary results.

J Chin Med Assoc 2018 Oct 13;81(10):884-891. Epub 2018 Jul 13.

Division of Endocrinology & Metabolism, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC. Electronic address:

Background: The aim of this study was to identify genotypic and phenotypic cardiovascular metabolic risk factors, and to establish risk models of diseases, including diabetes mellitus, cardiovascular disease, stroke, kidney dysfunction and psychiatric disorders, in Taiwanese adults.

Methods: In 2009, a community-based cohort study was initiated in the Shipai area of the Shilin and Beitou districts in Taipei. Residents were randomly sampled by age (young adults: 35-44 years and middle-aged adults: 45-55 years) and urbanization (rural and urban). Read More

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http://dx.doi.org/10.1016/j.jcma.2018.04.006DOI Listing
October 2018
7 Reads
0.890 Impact Factor

Outcome of perioperative hemostatic management in patients with hemophilia without inhibitors undergoing 161 invasive or surgical procedures.

J Chin Med Assoc 2018 Oct 13;81(10):926-929. Epub 2018 Jul 13.

Division of Urology, Department of Surgery, Taichung Veterans General Hospital, Taichung, Taiwan, ROC.

Perioperative management of persons with hemophilia (PWH) is a challenge for surgeons and hematologists. Reductions in mortality rate and complications have been achieved since the introduction of clotting factor concentrates (CFCs), which improve hemostatic control. However, there is no clear consensus on the optimal dosing of CFC administration. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17264901183017
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http://dx.doi.org/10.1016/j.jcma.2017.11.016DOI Listing
October 2018
2 Reads

Use of prokinetic agents or antibiotics is associated with the occurrence of spontaneous bacterial peritonitis in cirrhotic patients.

J Chin Med Assoc 2018 Nov 13;81(11):935-941. Epub 2018 Jul 13.

Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC. Electronic address:

Background: Prokinetics have been shown to improve intestinal bacterial overgrowth and dysmotility in cirrhotic patients. Antibiotics are suggested for high risk patients for prophylaxis of spontaneous bacterial peritonitis (SBP). However, limited studies have investigated the association of SBP and these medications. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.01.013DOI Listing
November 2018

Characterization and management of various renal cystic lesions by sonographic features.

J Chin Med Assoc 2018 Dec 13;81(12):1017-1026. Epub 2018 Jul 13.

Department of Radiology, Taipei Veterans General Hospital and National Yang-Ming University, School of Medicine, Taipei, Taiwan, ROC; Yee Zen Hospital, Taoyuan, Taiwan, ROC; Yuanpei University of Medical Technology, Hsinchu, Taiwan, ROC. Electronic address:

Renal cysts are common incidental findings in clinical practice. Most renal cysts detected in medical imaging are benign simple cysts. However, some are complicated by hemorrhage or infection or are associated with calcification. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.04.008DOI Listing
December 2018
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Composition of urinary tract stones formed by children in two populations in the Uyghur region of China.

J Chin Med Assoc 2018 Nov 13;81(11):949-954. Epub 2018 Jul 13.

Department of Urology, Minimally Invasive Surgery Center, Guangzhou Institute of Urology, Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China. Electronic address:

Background: To retrospectively compare the composition of urinary tract stones formed by Uyghur children from the southern (Kashgar) and northern (Urumchi) parts of the Xinjiang region.

Methods: The chemical composition of urinary tract calculi formed by 855 Uyghur children from the two regions in Xinjiang (366 Kashgar and 489 Urumchi) was compared retrospectively. Stone composition was determined by infrared spectroscopy. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.04.007DOI Listing
November 2018
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Comparison of the 2017 Taiwan lipid guidelines and the Western lipid guidelines for high risk patients.

J Chin Med Assoc 2018 Oct 3;81(10):853-859. Epub 2018 Jul 3.

Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC.

Dyslipidemia is a major contributor in initiation, development and progression of atherosclerotic cardiovascular disease (ASCVD). Most lipid guidelines are from Europe and America and centered on the reduction of atherogenic lipids levels through lifestyle intervention and pharmacotherapy. Recently, the 2017 Taiwan lipid guidelines for high risk patients was published to facilitate the control of dyslipidemia in patients that are highly susceptible to ASCVD, including patients with preexisting ASCVD, diabetes, chronic kidney disease and familial hypercholesterolemia. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.05.003DOI Listing
October 2018

Acoustic waves improves retroviral transduction in human retinal stem cells.

J Chin Med Assoc 2018 Sep 22;81(9):830-836. Epub 2018 Jun 22.

Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; Department of Ophthalmology, School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC. Electronic address:

Backgrounds: The plasticity of retinal stem cells (RSCs), a type of cells that can differentiate into neuron cells and photoreceptor cells, endows them with potential therapeutic properties that can be applied to regenerative medicine. Gene modification of these stem cells before trans-differentiation and transplantation enhances their survival and increases their therapeutic function. The different ways to effectively deliver gene into RSCs are still discussed. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.05.002DOI Listing
September 2018
0.890 Impact Factor

Modified Siegel's criteria for sudden sensorineural hearing loss: Reporting recovery outcomes with matched pretreatment hearing grades.

J Chin Med Assoc 2018 Nov 19;81(11):1008-1012. Epub 2018 Jun 19.

Department of Otolaryngology-Head and Neck Surgery, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC. Electronic address:

Background: Sudden sensorineural hearing loss (SSNHL) is an emergency clinical otology condition defined as hearing loss greater than 30 dB over three consecutive frequencies within 72 h. We aimed to integrate pretreatment hearing grades with reports of treatment recovery outcomes of SSNHL using the modified Siegel's criteria.

Methods: This was a retrospective cohort study comprising 110 patients with SSNHL seen between January 2014 and January 2015. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.03.012DOI Listing
November 2018
5 Reads

Mutational screening of GABRG2 gene in Pakistani population of Punjab with generalized tonic clonic seizures and children with childhood absence epilepsy.

J Chin Med Assoc 2018 Aug 19;81(8):665-669. Epub 2018 Jun 19.

Department of Biotechnology, Faculty of Science, University of Sialkot, Sialkot, Pakistan.

Background: Epilepsy is a multifaceted and multistep disorder that disrupts the proper functioning of neurons. It is becoming increasingly clear that the responsiveness of neurons depends on the appropriate trafficking of ions across the channels in the membrane of neurons. In line with this notion, impairment among these ion channels due to mutations has gain increasing attention in molecular neuroscience. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.05.001DOI Listing
August 2018
9 Reads

Spontaneous chronic subdural hematoma in elderly people - Arterial hypertension and other risk factors.

J Chin Med Assoc 2018 Sep 19;81(9):781-786. Epub 2018 Jun 19.

Department of Neurosurgery, Faculty of Medicine, Medical University-Plovdiv, Plovdiv, Bulgaria.

Background: The risk factors implicated in the genesis of chronic subdural hematomas include old age, alcoholism, diabetes mellitus, arachnoid cysts, coagulopathy, anticoagulant (ACTh) and antiplatelet drugs. However, no study has reported an association between arterial hypertension (HTA) and chronic subdural hematomas. Therefore, the aim of this study was to investigate whether HTA is a risk factor for spontaneous chronic subdural hematomas (SCSDHs). Read More

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http://dx.doi.org/10.1016/j.jcma.2018.03.010DOI Listing
September 2018
5 Reads

Cost of illness of leukemia in Japan - Trend analysis and future projections.

J Chin Med Assoc 2018 Sep 19;81(9):796-803. Epub 2018 Jun 19.

Department of Social Medicine, Toho University Graduate School of Medicine, Omori-nishi, Ota-ku, Tokyo, Japan. Electronic address:

Background: Leukemia is a deadly hematological malignancy that usually affects all age groups and imposes significant burden on public funds and society. The objective of this study was to analyze the cost of illness (COI) of leukemia, and to mark out the underlying driving factors, in Japan.

Methods: COI method was applied to the data from government statistics. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.02.005DOI Listing
September 2018

The effect of rheumatoid arthritis on the risk of cerebrovascular disease and coronary artery disease in young adults.

J Chin Med Assoc 2018 Sep 1;81(9):772-780. Epub 2018 Jun 1.

School of Public Health, College of Public Health, Taipei Medical University, Taipei, Taiwan, ROC. Electronic address:

Background: Only a few studies have investigated the affect of rheumatoid arthritis (RA) on the risk of cerebrovascular disease (CVD)/coronary artery disease (CAD) in young adults. This study, therefore, examined the association between RA and the risk of CVD/CAD in young adults and the interaction effects between cardiovascular risk factors and RA on the risk of CVD/CAD.

Methods: Data regarding 52,840 subjects (10,568 patients with RA and 42,272 age-, sex-, urbanization-, and income-matched non-RA controls) were collected from the National Health Insurance Research Database (NHIRD) in 2006. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.03.009DOI Listing
September 2018
2 Reads
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Flexible bronchoscopic findings and the relationship to repeated extubation failure in critical children.

J Chin Med Assoc 2018 Sep 31;81(9):804-810. Epub 2018 May 31.

Institute of Emergency and Critical Care Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC; Department of Pediatrics, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; Department of Pediatrics, School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC. Electronic address:

Background: Extubation failure (EF) in acute pediatric cases causes high morbidity and prolonged hospitalization, some of which might encounter EF repeatedly. This study aims to investigate flexible bronchoscopic findings of airway problems associated with repeated EF (REF) in children.

Methods: We retrospectively reviewed the medical records of intubated children from 2005 to 2013 and enrolled those with EF (reintubated within 48 h after extubation) and receiving flexible bronchoscopy (FB) examinations. Read More

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http://dx.doi.org/10.1016/j.jcma.2018.03.008DOI Listing
September 2018