6,361 results match your criteria Journal of the American Academy of Child and Adolescent Psychiatry[Journal]


Early Pubertal Timing and Testosterone Associated With Higher Levels of Adolescent Depression in Girls.

J Am Acad Child Adolesc Psychiatry 2019 Feb 14. Epub 2019 Feb 14.

Duke University Medical Center, Durham, NC.

Objective: The prevalence of depression increases dramatically during puberty in girls. Earlier work in this sample reported that the sex steroids estradiol and testosterone were associated with increased depression in girls. Using three additional data waves (983 new Observations), we retest the relative contributions of pubertal timing, pubertal status and sex hormones on the increases in female depression. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2019.02.007DOI Listing
February 2019

Quantifying the Optimal Structure of the Autism Phenotype: A Comprehensive Comparison of Dimensional, Categorical, and Hybrid Models.

J Am Acad Child Adolesc Psychiatry 2018 Oct 29. Epub 2018 Oct 29.

Stony Brook University, NY.

Objective: The two primary - seemingly contradictory - strategies for classifying child psychiatric syndromes are categorical and dimensional; conceptual ambiguities appear to be greatest for polythetic syndromes such as autism spectrum disorder (ASD). Recently, a compelling alternative has emerged that integrates both categorical and dimensional approaches (ie, hybrid model) thanks to the increasing sophistication of analytic procedures. This study aimed to quantify the optimal phenotypic structure of ASD by comprehensively comparing categorical, dimensional, and hybrid models. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2018.09.431DOI Listing
October 2018

Reducing Preschool Behavior Problems in an Urban Mental Health Clinic: A Pragmatic, Non-Inferiority Trial.

J Am Acad Child Adolesc Psychiatry 2018 Nov 12. Epub 2018 Nov 12.

Johns Hopkins School of Nursing, Baltimore, MD. At the time of the study; University of Maryland School of Medicine, Baltimore, and the US Department of Veteran Affairs VISN5 MIRECC, Baltimore, MD.

Objective: This pragmatic, randomized, non-inferiority trial compared the effectiveness and cost of group-based parent management training (PMT) versus mastery-based individual coaching PMT in a low-income, predominantly African American sample.

Method: Parents seeking treatment for their 2-5 year old children's behavior problems in an urban fee-for-service child mental health clinic were randomized to the Chicago Parent Program (CPP; n=81) or Parent-Child Interaction Therapy (PCIT; n=80). Consent followed clinic intake and diagnostic assessment and PMT was delivered by clinicians employed at the clinic. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2018.08.013DOI Listing
November 2018

Heart Rate as a Biomarker for Co-Occurring Externalizing and Internalizing Problems.

Authors:
Kostas A Fanti

J Am Acad Child Adolesc Psychiatry 2018 Dec 20. Epub 2018 Dec 20.

University of Cyprus, Nicosia, Cyprus. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2018.11.009DOI Listing
December 2018

Maternal Depression and Stress in the NICU: Associations With Mother-Child Interactions at Age 5 Years.

J Am Acad Child Adolesc Psychiatry 2019 Jan 3. Epub 2019 Jan 3.

Washington University School of Medicine, St. Louis, MO.

Objective: Previous studies suggest that maternal postpartum mental health issues may impact parenting and child development in preterm infants, but have often not measured symptomatology in the Neonatal Intensive Care Unit (NICU) nor followed families through early childhood. This study examines how maternal depressive symptoms and stress in the NICU are related to parenting behaviors at age 5 years, in mothers of children born very preterm (≤30 weeks gestation).

Method: This longitudinal study followed a diverse sample of 74 very preterm children and their mothers. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2018.08.016DOI Listing
January 2019
1 Read

Ethnic Differences in Referral Routes to Youth Mental Health Services.

J Am Acad Child Adolesc Psychiatry 2019 Jan 4. Epub 2019 Jan 4.

Institute of Psychology, Health and Society, University of Liverpool, UK.

Objective: To examine whether there are ethnic differences in referral route to youth mental health services.

Method: This was an analysis of national routinely collected data from N = 14,588 young people (mean [SD] age = 12.28(3. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2018.07.906DOI Listing
January 2019

Trajectories of Symptom Change in the Treatment for Adolescents With Depression Study.

J Am Acad Child Adolesc Psychiatry 2019 Jan 8. Epub 2019 Jan 8.

Abacist Analytics, Austin, TX and the University of Texas, Austin.

Objective: Depression is the most prominent mental health disorder among youth with profound impacts with respect to morbidity and mortality if not addressed. The Treatment for Adolescent Depression Study (TADS) is one of the largest randomized controlled trials that compared the effectiveness of four treatments: Cognitive Behavioral Therapy (CBT), fluoxetine (FLX), combined Cognitive Behavioral and fluoxetine treatment (COMB), and placebo (PBO). However, meaningful heterogeneous treatment courses are masked by these group mean comparisons of treatment impact. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2018.07.908DOI Listing
January 2019

Common Polygenic Variations for Psychiatric Disorders and Cognition in Relation to Brain Morphology in the General Pediatric Population.

J Am Acad Child Adolesc Psychiatry 2019 Jan 9. Epub 2019 Jan 9.

Erasmus University Medical Center, Rotterdam, the Netherlands.

Objective: To examine the relationship between polygenic scores (PGS) for five major psychiatric disorders and two cognitive traits with brain MRI morphological measurements in a large population-based sample of children. Additionally, we tested whether differences in brain morphology mediated associations between PGS for psychiatric disorders and related behavioral phenotypes.

Method: The participants included 1,139 children from the Generation R Study assessed at 10 years-of-age with genotype and neuroimaging data available. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S08908567193000
Publisher Site
http://dx.doi.org/10.1016/j.jaac.2018.09.443DOI Listing
January 2019
1 Read

A Longitudinal Follow-Up Study Examining Adolescent Depressive Symptoms as a Function of Prior Anxiety Treatment.

J Am Acad Child Adolesc Psychiatry 2019 Jan 16. Epub 2019 Jan 16.

Objective: Children who are fearful and anxious are at heightened risk for developing depression in adolescence. Treating anxiety disorders in pre/early adolescence may be one mechanism through which depressive symptoms later in adolescence can be prevented. We hypothesized that anxious youth who responded positively to cognitive behavioral therapy (CBT) for anxiety would show reduced onset of depressive symptoms 2 years later compared to treatment non-responders, and that this effect would be specific to youth treated with CBT compared to an active supportive comparison treatment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2018.10.012DOI Listing
January 2019

Editorial: Could a Treatment for Youth Anxiety Specifically Prevent the Emergence of Depression Two Years Later?

Authors:
Anne L Glowinski

J Am Acad Child Adolesc Psychiatry 2019 Jan 18. Epub 2019 Jan 18.

Washington University School of Medicine, St. Louis, MO. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2019.01.003DOI Listing
January 2019

Underlying Psychophysiology of Dysregulation: Resting Heart Rate and Heart Rate Reactivity in Relation to Childhood Dysregulation.

J Am Acad Child Adolesc Psychiatry 2018 Oct 31. Epub 2018 Oct 31.

Erasmus University Rotterdam, The Netherlands.

Objective: High co-occurrence of externalizing and internalizing problems could underlie inconsistent findings regarding the relation between heart rate (HR) and psychopathology. In this study, HR measures were examined in relation to a general dysregulation profile studied from variable- and person-centered approaches.

Method: The sample (N = 182) consisted of 8- to 12-year-old children referred for externalizing behaviors and typically developing children (mean age 9. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2018.09.434DOI Listing
October 2018

Prevalence and Correlates of Hypersomnolence Symptoms in US Teens.

J Am Acad Child Adolesc Psychiatry 2018 Oct 30. Epub 2018 Oct 30.

Genetic Epidemiology Research Branch, Intramural Research Program, National Institute of Mental Health, Bethesda, MD.

Objective: Recent attention to pervasive sleep deficits in U.S. adolescents has focused on sleep patterns and insomnia, but there are limited data on the prevalence and correlates of hypersomnolence symptoms. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2018.09.435DOI Listing
October 2018

Sertraline Effects on Striatal Resting-State Functional Connectivity in Youth With OCD: A Pilot Study.

J Am Acad Child Adolesc Psychiatry 2018 Oct 30. Epub 2018 Oct 30.

University of Minnesota, Minneapolis, MN.

Objective: Foundational knowledge on neural circuitry underlying pediatric obsessive-compulsive disorder (OCD) and how it changes during standard treatment is needed to provide the basis for conceptualization and development of novel, targeted treatments. This study explored the effects of sertraline, a selective serotonin reuptake inhibitor, on resting-state functional connectivity (RSFC) in cortico-striatal-thalamic-cortical circuits in pediatric OCD.

Method: Medication-free youths with OCD (n=14) and healthy controls (n=14) were examined at baseline and 12 weeks with resting-state fMRI. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2018.07.897DOI Listing
October 2018

Deficient Functioning of Fronto-Striatal Circuits During the Resolution of Cognitive Conflict in Cannabis-Using Youth.

J Am Acad Child Adolesc Psychiatry 2018 Oct 30. Epub 2018 Oct 30.

New York State Psychiatric Institute and the Department of Psychiatry, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY.

Objective: Disturbances in self-regulatory control are involved in the initiation and maintenance of addiction, including cannabis use disorder (CUD). In adults, chronic cannabis use is associated with disturbances in fronto-striatal circuits during tasks that require the engagement of self-regulatory control, including the resolution of cognitive conflict. Understudied are the behavioral and neural correlates of these processes earlier in the course of cannabis use, disentangled from effects of long-term use. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2018.09.436DOI Listing
October 2018

Prescription Drug Misuse: Sources of Controlled Medications in Adolescents.

J Am Acad Child Adolesc Psychiatry 2018 Oct 30. Epub 2018 Oct 30.

Center for the Study of Drugs, Alcohol, Smoking and Health, School of Nursing, University of Michigan, Ann Arbor, and the Institute for Research on Women and Gender, University of Michigan, Ann Arbor.

Objective: Adolescent controlled prescription drug misuse (PDM) co-occurs with significant consequences, including lower educational achievement, substance use disorder (SUD) symptoms, and psychopathology. Nonetheless, adolescent PDM sources and the prevalence of other substance use, SUD and mental health outcomes associated with sources remain poorly understood.

Method: Data were from the 2009-2014 National Survey on Drug Use and Health, including 103,920 adolescents (12-17 years). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2018.09.438DOI Listing
October 2018

Shortened Sleep Duration Causes Sleepiness, Inattention, and Oppositionality in Adolescents With ADHD: Findings From a Crossover Sleep Restriction/Extension Study.

J Am Acad Child Adolesc Psychiatry 2018 Nov 1. Epub 2018 Nov 1.

Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, OH, and the University of Cincinnati College of Medicine, Cincinnati, OH.

Objective: Although poor sleep is often reported in adolescents with attention-deficit/hyperactivity disorder (ADHD), prior studies have been correlational. This study investigated whether sleep duration is causally linked to sleepiness, inattention, and behavioral functioning in adolescents with ADHD.

Method: Seventy-two adolescents (ages 14-17 years) entered a three-week sleep protocol using an experimental crossover design. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2018.09.439DOI Listing
November 2018

Psychotic-Like Experiences in Offspring of Parents With Bipolar Disorder and Community Controls: A Longitudinal Study.

J Am Acad Child Adolesc Psychiatry 2018 Nov 2. Epub 2018 Nov 2.

University of Pittsburgh, PA.

Objective: To compare the prevalence and risk factors associated with Psychotic-Like-Experiences (PLE) in offspring of parents with bipolar disorder (BP) and offspring of community control parents.

Method: Delusional and hallucinatory subclinical psychotic experiences were evaluated at intake and longitudinally in a cohort study of 390 offspring of BP parents and 247 offspring of control parents aged 6-18 years old. The sample was followed up every 2. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2018.09.440DOI Listing
November 2018

Adolescent Victimization and Self-Injurious Thoughts and Behaviors: A Genetically Sensitive Cohort Study.

J Am Acad Child Adolesc Psychiatry 2018 Dec 11. Epub 2018 Dec 11.

King's College London, UK; National and Specialist CAMHS Trauma and Anxiety Clinic, South London and Maudsley NHS Foundation Trust, London, UK. Electronic address:

Objective: Victimized adolescents have elevated risk of self-injurious thoughts and behaviors. However, poor understanding of causal and non-causal mechanisms underlying this observed risk limits the development of interventions to prevent premature death among adolescents. We tested whether pre-existing family-wide and individual vulnerabilities account for victimized adolescents' elevated risk of self-injurious thoughts and behaviors. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2018.07.903DOI Listing
December 2018

Reading Acquisition in Children: Developmental Processes and Dyslexia Specific Effects.

J Am Acad Child Adolesc Psychiatry 2018 Dec 6. Epub 2018 Dec 6.

Polish Academy of Sciences, Nencki Institute of Experimental Biology, Warsaw, Poland. Electronic address:

Objective: Reduced activation to print in the left ventral, dorsal and anterior pathways has been implicated in readers with dyslexia (DR) but is also characteristic for typical beginning readers. As the majority of studies compared DR to their age-matched peers, the observed results could either represent a dyslexia phenotype or a developmental delay. We aimed to disentangle reading and dyslexia effects by employing two control groups: age and skill matched, and a longitudinal design. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2018.11.007DOI Listing
December 2018

A Longitudinal Study of Family Functioning in Offspring of Bipolar Parents.

J Am Acad Child Adolesc Psychiatry 2018 Dec 18. Epub 2018 Dec 18.

Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, PA.

Objective: To compare the longitudinal course of family functioning in offspring of parents with bipolar disorder (BD), offspring of parents with non-BD psychopathology, and offspring of healthy control parents (HC).

Method: Offspring of BD parents (256 parents and 481 offspring), non-BD parents (82 parents and 162 offspring) and HC parents (88 parents and 175 offspring) ages 7-18 at intake, from the Bipolar Offspring Study (BIOS), were followed for an average of 4.3 years. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2018.10.011DOI Listing
December 2018

Sex Differences in Comorbidity Patterns of Attention-Deficit/Hyperactivity Disorder.

J Am Acad Child Adolesc Psychiatry 2019 Jan 8. Epub 2019 Jan 8.

National Centre for Register- based Research, School of Business and Social Sciences, Aarhus University, Aarhus, Denmark, and The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark; Hospital of Telemark, Kragerø, Norway.

Objective: To investigate sex differences in associations between attention-deficit/hyperactivity disorder (ADHD) and a spectrum of comorbid disorders.

Method: The study population included all children born in Denmark between 1981 and 2013 (N=1,665,729). We merged data from Danish registers and obtained information on birth characteristics, socioeconomic status, familial psychiatric history, and diagnoses of ADHD (n=32,308) and comorbid disorders. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2018.07.910DOI Listing
January 2019

Consequences of Not Planning Ahead: Reduced Proactive Control Moderates Longitudinal Relations Between Behavioral Inhibition and Anxiety.

J Am Acad Child Adolesc Psychiatry 2019 Jan 8. Epub 2019 Jan 8.

University of Maryland, College Park.

Objective: Children with the temperament of Behavioral Inhibition (BI) face increased risk for developing an anxiety disorder later in life. However, not all children with BI manifest anxiety symptoms, and cognitive-control-strategy use may moderate the pathway between BI and anxiety. Individuals vary widely in the strategy used to instantiate control; the present study examined whether a more planful style of cognitive control (i. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2018.06.040DOI Listing
January 2019

Changes in General and Specific Psychopathology Factors Over a Psychosocial Intervention.

J Am Acad Child Adolesc Psychiatry 2019 Jan 14. Epub 2019 Jan 14.

Division of Psychology and Language Sciences, University College London, UK.

Objective: Recent research suggests that comorbidity among child and adolescent psychiatric symptoms can be explained by a single general psychopathology ('p') factor, as well as more specific factors summarizing clusters of symptoms. We investigated within- and between-person changes in the general and specific psychopathology factors over a psychosocial intervention.

Method: We ran a secondary analysis of the Systemic Therapy for At-Risk Teens study, a pragmatic randomized controlled trial that compared the effects of multisystemic therapy to management-as-usual for reducing antisocial behavior in 684 adolescents (82% male; 11-18 at baseline) over an 18-month period. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2018.11.011DOI Listing
January 2019

Structural Brain Alterations in Youth With Psychosis and Bipolar Spectrum Symptoms.

J Am Acad Child Adolesc Psychiatry 2019 Jan 17. Epub 2019 Jan 17.

Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles; Center for Neurobehavioral Genetics, University of California, Los Angeles; University of California, Los Angeles.

Objective: Adults with established diagnoses of serious mental illness (bipolar disorder and schizophrenia) exhibit structural brain abnormalities, yet less is known about how such abnormalities manifest earlier in development.

Method: We analyzed the cross-sectional data publicly available from the Philadelphia Neurodevelopmental Cohort (PNC). Structural magnetic resonance neuroimaging data (sMRI) were collected on a subset of the PNC (N=989, ages 9-22 years old). Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S08908567193004
Publisher Site
http://dx.doi.org/10.1016/j.jaac.2018.11.012DOI Listing
January 2019
2 Reads

A Multisite Randomized Controlled Two-Phase Trial of the Early Start Denver Model Compared to Treatment as Usual.

J Am Acad Child Adolesc Psychiatry 2019 Jan 24. Epub 2019 Jan 24.

University of California, Davis MIND Institute, Sacramento, CA.

Objective: This single-blind, randomized, multi-site, intent-to-treat study was designed to replicate and extend Dawson et al.'s (2010) randomized controlled trial (RCT) testing effects of the Early Start Denver Model (ESDM), an intensive play-and routines-based intervention delivered in natural settings.

Method: An RCT was conducted at three universities. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2019.01.004DOI Listing
January 2019

Double-Blind, Sham-Controlled, Pilot Study of Trigeminal Nerve Stimulation for ADHD.

J Am Acad Child Adolesc Psychiatry 2019 Jan 28. Epub 2019 Jan 28.

Semel Institute for Neuroscience and Human Behavior and David Geffen School of Medicine at UCLA, Los Angeles, CA.

Objective: Trigeminal nerve stimulation (TNS), a minimal risk, non-invasive neuromodulation method, has showed potential benefits for attention-deficit/hyperactivity disorder (ADHD) in an unblinded open study. This blinded sham-controlled trial was conducted to assess efficacy and safety of TNS for ADHD, as well as potential changes in brain spectral power using resting-state quantitative electroencephalography (qEEG).

Method: 62 children aged 8-12 years, with full-scale IQ ≥ 85 and KSADS-diagnosed ADHD, were randomized to four weeks nightly treatment with active or sham TNS, followed by one-week without intervention. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S08908567193004
Publisher Site
http://dx.doi.org/10.1016/j.jaac.2018.11.013DOI Listing
January 2019
1 Read

Paternal Psychological Distress and Child Problem Behavior from Early Childhood to Middle Adolescence.

J Am Acad Child Adolesc Psychiatry 2019 Feb 1. Epub 2019 Feb 1.

UCL Institute of Education, University College London, UK.

Objective: To explore if paternal psychological distress is related to the longitudinal course of child Problem behaviour after accounting for maternal psychological distress.

Method: We used data from the Millennium Cohort Study (MCS), a large general-population birth cohort in the UK. Maternal and paternal psychological distress was measured with the Kessler 6-item psychological distress scale (K-6) at child ages 3, 5, 7, 11 and 14 years. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2018.06.041DOI Listing
February 2019

Attention-Deficit/Hyperactivity Disorder, School Performance, and Effect of Medication.

J Am Acad Child Adolesc Psychiatry 2019 Feb 1. Epub 2019 Feb 1.

Karolinska Institutet, Stockholm, Sweden; School of Medical Sciences, Örebro University, Örebro, Sweden.

Objective: Individuals with Attention-Deficit/Hyperactivity Disorder (ADHD) are at increased risk of poor school performance and pharmacological treatment of ADHD may have beneficial effects on school performance. Conclusions from previous research have been limited by small sample sizes, outcome measures, and treatment follow-up. The current study analyzed school performance in students with ADHD compared to students without ADHD, and the association between pharmacological treatment of ADHD and school performance. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2018.11.014DOI Listing
February 2019

Editorial: Time to Wake Up: Appreciating the Role of Sleep in ADHD.

J Am Acad Child Adolesc Psychiatry 2019 Feb 1. Epub 2019 Feb 1.

Research Institute Brainclinics, Nijmegen, The Netherlands. Dr. Arns is also with Utrecht University, Utrecht, The Netherlands; Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Centre, Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2018.10.013DOI Listing
February 2019

Editorial: Transcutaneous Trigeminal Nerve Stimulation for Children With ADHD.

J Am Acad Child Adolesc Psychiatry 2019 Feb 7. Epub 2019 Feb 7.

University of Toronto and the Temerty Centre for Therapeutic Brain Intervention and Campbell Family Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2019.01.006DOI Listing
February 2019

Families Who Benefit and Families Who Do Not: Integrating Person- and Variable-Centered Analyses of Parenting Intervention Responses.

J Am Acad Child Adolesc Psychiatry 2019 Feb 11. Epub 2019 Feb 11.

University of Amsterdam, The Netherlands.

Objective: Families with disruptive child behavior are typically referred to services based on children's behavior alone, rather than on underlying mechanisms of disruptive behavior. Yet, the presence of the precise mechanisms targeted by services might be essential for intervention success. We integrated person- and variable-centered approaches to test whether families with combined disruptive child behavior and harsh/inconsistent parenting indeed benefit most from a behavioral parenting intervention in indicated prevention context, compared to families with disruptive child behavior but less harsh/inconsistent parenting, and families with less severe disruptive behavior. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2019.02.004DOI Listing
February 2019

Association Between Repeated Episodes of Gastroenteritis and Mental Health Problems in Childhood and Adolescence.

J Am Acad Child Adolesc Psychiatry 2019 Feb 8. Epub 2019 Feb 8.

Douglas Mental Health University Institute, Ludmer Centre for Neuroinformatics and Mental Health, McGill University, Montreal, Quebec, Canada; Sackler Institute for Epigenetics & Psychobiology, McGill University, Quebec, Canada.

Objective: The Avon Longitudinal Study of Parents and Children (ALSPAC) and Maternal Adversity, Vulnerability and Neurodevelopment (MAVAN) cohorts were used to determine if repeated exposure to gastroenteritis in early life could predict risk for psychiatric problems in childhood and in ALSPAC adolescents. We determined if inflammatory biomarkers moderate the association between repeated gastroenteritis and mental health in adolescents from ALSPAC.

Method: Episodes of gastroenteritis from birth to 30 and 36 months were reported by mothers. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2019.01.007DOI Listing
February 2019

Editorial: Does a Diagnosis of ADHD in Childhood Determine an Increased Risk for Future Criminality?

J Am Acad Child Adolesc Psychiatry 2019 Feb 13. Epub 2019 Feb 13.

University of California, San Francisco, and Adult Mental Health Services, The Permanente Medical Group, Daly City, CA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2019.01.008DOI Listing
February 2019

Attention-Deficit/Hyperactivity Disorder in Childhood and Adolescence and the Risk of Crime in Young Adulthood in a Danish Nationwide Study.

J Am Acad Child Adolesc Psychiatry 2019 Feb 11. Epub 2019 Feb 11.

University of Aalborg, Denmark; University of Southern Denmark, Odense, Denmark; the Child and Adolescent Mental Health Centre, Capital Region Psychiatry, Copenhagen, Denmark; Psychiatric University Hospital, Zurich, Switzerland, and Clinical Psychology and Epidemiology, Institute of Psychology, University of Basel, Switzerland.

Objective: To determine the risk of long-term conviction and incarceration associated with childhood attention-deficit/hyperactivity disorder (ADHD), and to identify risk and protective factors including associations with active treatment with ADHD medication.

Method: All participants with ADHD aged 4-15 during 1995 - 2005 were matched by year of birth and sex to a random sample of participants without ADHD from the Danish population using nationwide registers. Using Cox proportional hazard models we estimated the risk of conviction and incarceration associated with ADHD in childhood and estimated associations with active treatment on outcome. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2018.11.016DOI Listing
February 2019

Editorial: Elevating the Narrative About Adverse Events During Development.

Authors:
Anne L Glowinski

J Am Acad Child Adolesc Psychiatry 2019 Feb 12. Epub 2019 Feb 12.

William Greenleaf Eliot Division of Child Psychiatry, Washington University School of Medicine, St. Louis, MO. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2019.01.009DOI Listing
February 2019

Treatment Gains Are Sustainable in Pediatric Obsessive-Compulsive Disorder: Three-Year Follow-Up From the NordLOTS.

J Am Acad Child Adolesc Psychiatry 2019 Feb 13. Epub 2019 Feb 13.

Objective: This study evaluates the long-term outcomes of a stepped care treatment for pediatric obsessive-compulsive disorder (OCD) and investigates whether response to first-step cognitive-behavioral therapy (CBT) is an important indicator of three-year outcomes.

Method: This study is a part of the Nordic Long-term OCD Treatment study (NordLOTS), in which 269 children and adolescents were treated with CBT. Non-responders to CBT were randomized to an extended treatment with continued CBT or pharmacotherapy with sertraline. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S08908567193010
Publisher Site
http://dx.doi.org/10.1016/j.jaac.2019.01.010DOI Listing
February 2019
2 Reads

Association Between Age and Familial Risk for Alcoholism on Functional Connectivity in Adolescence.

J Am Acad Child Adolesc Psychiatry 2019 Feb 13. Epub 2019 Feb 13.

Objective: Youth with a family history of alcohol use disorder (family history positive; FHP) are at increased risk for developing maladaptive substance use relative to family history negative (FHN) peers. Building on earlier studies demonstrating morphological differences and distinct patterns of neural activation in FHP, the purpose of the present study was to investigate differential intrinsic functional connectivity among brain networks indexing premorbid risk of developing alcohol use disorder (AUD).

Method: The current study examined intrinsic functional connectivity using resting state functional magnetic resonance imaging (fMRI) in 191 adolescents 13 to 18 years with and without family history of alcohol use disorder (AUD) via independent component analysis (ICA), a method enabling data-driven investigation of internetwork and intranetwork connectivity among brain regions at rest. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2018.12.008DOI Listing
February 2019

Beyond a Binary Classification of Sex: An Examination of Brain Sex Differentiation, Psychopathology, and Genotype.

J Am Acad Child Adolesc Psychiatry 2018 Oct 9. Epub 2018 Oct 9.

Stanford University, CA.

Objective: Sex differences in the brain are traditionally treated as binary. We present new evidence that a continuous measure of sex differentiation of the brain can explain sex differences in psychopathology. The degree of sex differentiated brain features (ie, features that are more common in one sex) may predispose individuals toward sex-biased psychopathology and may also be influenced by the genome. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2018.09.425DOI Listing
October 2018

Abnormal Spontaneous Regional Brain Activity in Young Patients With Anorexia Nervosa.

J Am Acad Child Adolesc Psychiatry 2019 Feb 15. Epub 2019 Feb 15.

Division of Psychological and Social Medicine and Developmental Neuroscience, Faculty of Medicine, Technische Universität Dresden, Dresden, Germany; Translational Developmental Neuroscience Section, Eating Disorder Research and Treatment Center, Faculty of Medicine, Technische Universität Dresden, Dresden, Germany. Electronic address:

Objective: Functional MRI studies have repeatedly shown alterations in patients with anorexia nervosa (AN). These alterations might be driven by baseline signal characteristics such as the (fractional) amplitude of low frequency fluctuations (fALFF/ALFF), as well as regional signal consistency [ie. regional homogeneity (ReHo)] within circumscribed brain regions. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S08908567193011
Publisher Site
http://dx.doi.org/10.1016/j.jaac.2019.01.011DOI Listing
February 2019
1 Read

Parent Pleas.

Authors:
Julie A Chilton

J Am Acad Child Adolesc Psychiatry 2019 Feb;58(2):297

Child psychiatrists might easily misread the above title as "Parent, please!" due to the helplessness we feel after realizing no amount of medication or individual talk therapy can change the all-powerful home dynamic. Assuming parents are doing the best they can, but they need to (and can do) better with additional support provides a helpful reframe, á la Dialectical Behavior Therapy. Likewise, Collaborative Problem Solving, Ross Greene and Stuart Ablon's evidence-based approach to helping kids with behavior issues, reminds us that "challenging kids lack the skill, not the will, to behave well. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S08908567183202
Publisher Site
http://dx.doi.org/10.1016/j.jaac.2018.11.004DOI Listing
February 2019
2 Reads

Lithium for the Maintenance Treatment of Bipolar I Disorder: A Double-Blind, Placebo-Controlled Discontinuation Study.

J Am Acad Child Adolesc Psychiatry 2019 Feb 26;58(2):287-296.e4. Epub 2018 Nov 26.

Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD.

Objective: This study examined the role of lithium in the maintenance treatment of pediatric patients with bipolar I disorder (BP-I).

Method: Participants aged 7 to 17 years who presented with a manic or mixed episode received 24 weeks of lithium treatment in one of two multiphase studies, the Collaborative Lithium Trials (CoLT 1 and CoLT 2). Responders were randomized to continue lithium or to be cross-titrated to placebo for up to 28 weeks. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S08908567183198
Publisher Site
http://dx.doi.org/10.1016/j.jaac.2018.07.901DOI Listing
February 2019
2 Reads

Obsessive-Compulsive Symptomatology in Community Youth: Typical Development or a Red Flag for Psychopathology?

J Am Acad Child Adolesc Psychiatry 2019 Feb 24;58(2):277-286.e4. Epub 2018 Nov 24.

Lifespan Brain Institute, Children's Hospital of Philadelphia and Penn Medicine, and the Neuropsychiatry Section of the Perelman School of Medicine, University of Pennsylvania, Philadelphia.

Objective: Obsessive-compulsive symptoms (OCS) are common throughout development and often considered developmentally appropriate. We evaluated the prevalence and phenotypic heterogeneity of self-reported OCS in a large community youth sample not ascertained for seeking mental-health help. We aimed to identify patterns in OCS that are associated with serious psychopathology and may thus represent a "red flag" that merits psychiatric evaluation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaac.2018.06.038DOI Listing
February 2019
1 Read

A Twin Study on the Association Between Psychotic Experiences and Tobacco Use During Adolescence.

J Am Acad Child Adolesc Psychiatry 2019 Feb 23;58(2):267-276.e8. Epub 2018 Nov 23.

Centre for Brain and Cognitive Development, University of London, UK. Electronic address:

Objective: Psychotic experiences (PE) are dimensional phenomena in the general population that resemble psychotic symptoms, such as paranoia and hallucinations. This is the first twin study to explore the degree to which tobacco use and PE share genetic or environmental influences. Previous studies on the association between adolescent tobacco use and PE have not considered PE dimensionally, included negative symptoms, or accounted for confounding by sleep disturbance and stressful life events. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S08908567183197
Publisher Site
http://dx.doi.org/10.1016/j.jaac.2018.06.037DOI Listing
February 2019
2 Reads

Brain Structure and Function in School-Aged Children With Sluggish Cognitive Tempo Symptoms.

J Am Acad Child Adolesc Psychiatry 2019 Feb 26;58(2):256-266. Epub 2018 Nov 26.

Institut de Salut Global de Barcelona (ISGlobal), Barcelona, Spain; Hospital del Mar Research Institute, Barcelona, and the Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Madrid, Spain.

Objective: Sluggish cognitive tempo (SCT) is a cluster of symptoms associated with poor function in various domains of major life activities that may comprise a novel attention disorder distinct from attention-deficit/hyperactivity disorder (ADHD). Nevertheless, very little is known about the neural substrate of SCT in children. The present study aimed to examine associations between SCT symptoms and brain structure and function in school-aged children. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S08908567183198
Publisher Site
http://dx.doi.org/10.1016/j.jaac.2018.09.441DOI Listing
February 2019
2 Reads

Early Sexual Trauma Exposure and Neural Response Inhibition in Adolescence and Young Adults: Trajectories of Frontal Theta Oscillations During a Go/No-Go Task.

J Am Acad Child Adolesc Psychiatry 2019 Feb 20;58(2):242-255.e2. Epub 2018 Dec 20.

State University of New York Downstate Medical Center, Brooklyn, NY.

Objective: Trauma, particularly when experienced early in life, can alter neurophysiologic and behavioral development, thereby increasing risk for substance use disorders and related psychopathology. However, few studies have empirically examined trauma using well-characterized developmental samples that are followed longitudinally.

Method: The association of assaultive, non-assaultive, and sexual assaultive experiences before 10 years of age with developmental trajectories of brain function during response inhibition was examined by measuring electrophysiologic theta and delta oscillations during no-go and go conditions in an equal probability go/no-go task. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S08908567183205
Publisher Site
http://dx.doi.org/10.1016/j.jaac.2018.07.905DOI Listing
February 2019
3 Reads
7.260 Impact Factor

Increased Functional Connectivity Between Ventral Attention and Default Mode Networks in Adolescents With Bulimia Nervosa.

J Am Acad Child Adolesc Psychiatry 2019 Feb 29;58(2):232-241. Epub 2018 Oct 29.

Division of Child and Adolescent Psychiatry, New York State Psychiatric Institute, New York, NY, and the Vagelos College of Physicians and Surgeons, Columbia University, New York, NY.

Objective: Bulimia nervosa (BN) is characterized by excessive attention to self and specifically to body shape and weight, but the ventral attention (VAN) and default mode (DMN) networks that support attentional and self-referential processes are understudied in BN. This study assessed whether altered functional connectivity within and between these networks contributes to such excessive concerns in adolescents with BN early the course of the disorder.

Method: Resting-state functional magnetic resonance images were acquired from 33 adolescents with BN and 37 healthy control adolescents (12-21 years) group matched by age and body mass index. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S08908567183190
Publisher Site
http://dx.doi.org/10.1016/j.jaac.2018.09.433DOI Listing
February 2019
2 Reads