9,061 results match your criteria Journal of surgical oncology[Journal]


The use of preoperative risk score to predict postoperative mortality following liver resection.

J Surg Oncol 2019 Feb 16. Epub 2019 Feb 16.

Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, Beijing, People's Republic of China.

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http://dx.doi.org/10.1002/jso.25406DOI Listing
February 2019

Evaluating the relationship between ductal carcinoma in situ, calcifications, and margin status in patients undergoing breast conserving surgery.

J Surg Oncol 2019 Feb 11. Epub 2019 Feb 11.

Division of Surgical Oncology, Department of Surgery, University of Louisville, Louisville, Kentucky.

Background: Microcalcifications associated with ductal carcinoma in situ (DCIS-AMC) close to lumpectomy margins could be used as a surrogate for margin involvement and aid in decreasing margin re-excision. We sought to evaluate the histologic factors of DCIS-AMC near lumpectomy margins.

Methods: Women with DCIS treated with breast-conserving surgery (BCS) who had DCIS-AMC on surgical specimens were identified. Read More

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http://dx.doi.org/10.1002/jso.25388DOI Listing
February 2019

Evaluation of treatment and outcomes for Hispanic patients with gastric cancer at Commission on Cancer-accredited centers in the United States.

J Surg Oncol 2019 Feb 11. Epub 2019 Feb 11.

Department of Surgery, University of California, San Diego, La Jolla, California.

Background And Objectives: Gastric cancer in the Hispanic population commonly presents with poor clinical features. Characteristics of this vulnerable population and optimal therapy for these patients have not been clearly defined.

Methods: Using the National Cancer Database (2004-2014), we analyzed patient demographics, clinical factors, treatment-related factors, and outcomes for Hispanic and non-Hispanic patients with gastric adenocarcinoma in the United States. Read More

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http://dx.doi.org/10.1002/jso.25408DOI Listing
February 2019
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Radio-guided vs clip-guided localization of nonpalpable mass-like lesions of the breast from a screened population: A propensity score-matched study.

J Surg Oncol 2019 Feb 11. Epub 2019 Feb 11.

Department of Biomedical and Clinical Sciences "Luigi Sacco", University of Milan, Milan, Italy.

Background And Objectives: An accurate localization is mandatory to tailor breast lumpectomy in nonpalpable cancers. The aim of this study was to compare radio-guided localization (ROLL) vs ultrasound localization of a titanium clip with collagen (TCC) in nonpalpable mass-like breast cancers.

Methods: Two hundred seventy-three consecutive patients were reviewed: 64 patients were localized by TCC and 209 patients by ROLL. Read More

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http://dx.doi.org/10.1002/jso.25409DOI Listing
February 2019

Ratio-based staging systems are better than the 7th and 8th editions of the TNM in stratifying the prognosis of gastric cancer patients: A multicenter retrospective study.

J Surg Oncol 2019 Feb 11. Epub 2019 Feb 11.

Dipartimento Scienze Gastroenterologiche, Endocrino-Metaboliche e Nefro-Urologiche, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.

Background: The current and the previous editions of the tumor-node-metastasis (TNM) system for gastric cancer (GC; TNM8 and TNM7) have a high risk of stage-migration bias when the node count after gastrectomy is suboptimal. Hence, they are possibly not the optimal staging systems for GC patients. This study aims to compare the TNM with two systems less affected by the stage-migration bias, namely, the lymph nodes ratio (LNR) and the log odds of positive lymph nodes (LODDS), to assess which one is the best in stratifying the prognosis of GC patients. Read More

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http://dx.doi.org/10.1002/jso.25411DOI Listing
February 2019
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Estrogen receptor beta expression correlates with proliferation in desmoid tumors.

J Surg Oncol 2019 Feb 11. Epub 2019 Feb 11.

Department of Oncology, Comprehensive Cancer Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.

Background And Objectives: Estrogen receptor signaling and cyclin D1 have a major role in tumor cell proliferation in breast cancer. Desmoid tumors are rare neoplasms that may respond to endocrine treatment. The present study aimed to investigate the expression levels and the clinical relevance of estrogen receptor beta (ERβ) and cyclin D1 in desmoid tumors. Read More

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http://dx.doi.org/10.1002/jso.25407DOI Listing
February 2019
1 Read

Perioperative outcomes of extensive bowel resection during cytoreductive surgery in patients with advanced ovarian cancer.

J Surg Oncol 2019 Feb 8. Epub 2019 Feb 8.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Ajou University School of Medicine, Suwon, Republic of Korea.

Background And Objectives: To achieve optimal cytoreduction, extensive bowel resections are sometimes required in patients with advanced ovarian cancer. Few studies have focused on the extent or number of resections of bowel surgeries and their feasibility.

Methods: We retrospectively reviewed the medical records of patients with advanced ovarian cancer who underwent bowel surgery as part of debulking procedures at Ajou University Hospital from 2006 to 2018. Read More

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http://dx.doi.org/10.1002/jso.25403DOI Listing
February 2019
1 Read
3.244 Impact Factor

Call for improved design and reporting in soft tissue sarcoma studies: A systematic review and meta-analysis of chemotherapy and survival outcomes in resectable STS.

J Surg Oncol 2019 Feb 8. Epub 2019 Feb 8.

Department of Surgery, Johns Hopkins Hospital, Baltimore, Maryland.

New evidence and systemic therapies demand an updated analysis of chemotherapy for soft tissue sarcoma. We completed a meta-analysis of chemotherapy in localized STS, assessing OS, PFS, and local and distant recurrence (local recurrence-free survival [LRFS] and distant recurrence-free survival [DRFS]). Ten studies, totaling 3157 patients, were included. Read More

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http://dx.doi.org/10.1002/jso.25401DOI Listing
February 2019

Risk factors for post-pancreaticoduodenectomy delayed gastric emptying in the absence of pancreatic fistula or intra-abdominal infection.

J Surg Oncol 2019 Feb 8. Epub 2019 Feb 8.

Department of Surgery, Surgical Outcomes and Quality Improvement Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

Background And Objectives: Delayed gastric emptying (DGE) occurs commonly following pancreaticoduodenectomy (PD), but the rate of DGE in the absence of other intra-abdominal complications is poorly understood. The objectives of this study were to define the incidence of DGE and identify risk factors for DGE in patients without pancreatic fistula or other intra-abdominal infections.

Methods: Retrospective cohort study utilizing the American College of Surgeons National Surgical Quality Improvement Program pancreatectomy variables to identify patients with DGE following PD without evidence of fistula or intra-abdominal infection. Read More

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http://dx.doi.org/10.1002/jso.25398DOI Listing
February 2019
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Long-term recurrence rates of whole specimen intraoperative frozen section analysis in basal cell carcinomas of the face with WIFSA.

J Surg Oncol 2019 Feb 8. Epub 2019 Feb 8.

Department of Plastic Surgery and Hand Surgery, Medical Centre Leeuwarden, Leeuwarden, The Netherlands.

Background And Objectives: Recent studies show that whole specimen intraoperative frozen section analysis (WIFSA) is a reliable method for margin analysis in basal cell carcinoma (BCC) and has low recurrence rates after five-years follow-up. There are no studies with longer follow-up. Our aim is to present long-term recurrence rates after WIFSA. Read More

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http://dx.doi.org/10.1002/jso.25396DOI Listing
February 2019
1 Read

Surgeon perception versus reality: Opioid use after breast cancer surgery.

J Surg Oncol 2019 Feb 8. Epub 2019 Feb 8.

Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Background: Few guidelines exist for an opioid prescription after breast surgical oncology (BSO) procedures. We sought to characterize opioid prescribing and use patterns by surgery type.

Methods: Patients (n = 332) undergoing BSO procedure were surveyed one week postoperatively for opioid use. Read More

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http://doi.wiley.com/10.1002/jso.25395
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http://dx.doi.org/10.1002/jso.25395DOI Listing
February 2019
8 Reads

Similar local recurrence but better function with curettage versus resection for bone giant cell tumor and pathological fracture at presentation.

J Surg Oncol 2019 Feb 7. Epub 2019 Feb 7.

Department of Orthopaedic Oncology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.

Background: There are conflicting reports for the outcome of the patients with giant cell tumor of bone (GCTB) and pathological fracture at presentation treated with curettage or resection. This study compared local recurrence, complications, and function after curettage versus resection for these patients.

Materials And Methods: We retrospectively studied the files of 46 patients with histologically confirmed GCTB of the extremities admitted and treated from 1982 to 2015. Read More

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http://dx.doi.org/10.1002/jso.25391DOI Listing
February 2019

Management of intussusception in patients with melanoma.

J Surg Oncol 2019 Feb 7. Epub 2019 Feb 7.

Department of Cutaneous Oncology, Moffitt Cancer Center, Tampa, Florida.

Background: Increased cross-sectional imaging for surveillance of metastatic melanoma has led to more diagnoses of asymptomatic intussusception.

Methods: We performed a multi-institutional retrospective review of patient records with a history of metastatic melanoma and a diagnosis of intussusception. Patients were divided into three groups: 1) asymptomatic patients without current evidence of melanoma (no evidence of disease [NED]); 2) asymptomatic intussusception and known active metastatic melanoma; 3) symptomatic intussusception and known active metastatic melanoma; the number of patients requiring surgery and intraoperative findings were recorded. Read More

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http://doi.wiley.com/10.1002/jso.25393
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http://dx.doi.org/10.1002/jso.25393DOI Listing
February 2019
2 Reads

A systematic review and meta-analysis of locoregional treatments for in-transit melanoma.

J Surg Oncol 2019 Feb 7. Epub 2019 Feb 7.

Queensland Melanoma Project, Princess Alexandra Hospital, Brisbane, Queensland, Australia.

Background And Objectives: In-transit melanoma (ITM) metastases present a therapeutic challenge and management decisions can be difficult. There are multiple treatments available, with differing efficacy, and supported by different levels of evidence. The primary objective was to perform a systematic review and where suitable, a meta-analysis of the literature reporting on the use of locoregional treatments for the management of ITM. Read More

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http://dx.doi.org/10.1002/jso.25400DOI Listing
February 2019

Low dose radiotherapy is associated with local complications but not disease control in sacral chordoma.

J Surg Oncol 2019 Feb 7. Epub 2019 Feb 7.

Division of Orthopaedic Surgery, Department of Surgery, University Musculoskeletal Oncology Unit Mount Sinai Hospital, University of Toronto, Toronto, Canada.

Background: We reviewed the disease control and complications of the treatment of sacrococcygeal chordoma from four tertiary cancer centers with emphasis on the effects of radiotherapy in surgically treated patients.

Methods: A total of 193 patients with primary sacrococcygeal chordoma from 1990 to 2015 were reviewed. There were 124 males, with a mean age of 59 ± 15 years and a mean follow-up of 7 ± 4 years. Read More

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http://dx.doi.org/10.1002/jso.25399DOI Listing
February 2019
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Perioperative and oncological outcomes of abdominoperineal resection in the prone position vs the classic lithotomy position: A systematic review with meta-analysis.

J Surg Oncol 2019 Feb 6. Epub 2019 Feb 6.

Department of Surgery, Barbara-Ann Karmanos Comprehensive Cancer Center, Detroit Medical Center/Wayne State University School of Medicine, Detroit, Michigan.

Background And Objectives: This study is a systematic review with meta-analysis designed to compare the perioperative and oncological outcomes of the abdominoperineal resection (APR) carried out in the prone jack-knife position (P-APR) vs the classic lithotomy position (C-APR).

Methods: We conducted an electronic search through PubMed utilizing the PRISMA guidelines. We included all randomized and nonrandomized studies which allowed for comparative analysis between the two groups. Read More

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http://dx.doi.org/10.1002/jso.25402DOI Listing
February 2019
1 Read
3.244 Impact Factor

Comparison of keystone flaps and skin grafts for oncologic reconstruction: A retrospective review.

J Surg Oncol 2019 Feb 6. Epub 2019 Feb 6.

Department of Plastic and Reconstructive Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland.

Background And Objectives: Two common options for the closure of complex defects are local flaps and skin grafting. The keystone flap, a fasciocutaneous flap based on perforators, has demonstrated compelling ease of use, reproducibility, and low complication rates without requiring a distant donor site. Our objective for this study was to compare postoperative outcomes for keystone flaps and skin grafts in cancer resection. Read More

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http://dx.doi.org/10.1002/jso.25394DOI Listing
February 2019
1 Read

Setting the "stage" for Surgical Oncology fellows: Pierre Denoix and TNM staging.

J Surg Oncol 2019 Feb 6. Epub 2019 Feb 6.

Department of Surgical Oncology, University of Texas - MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1002/jso.25404DOI Listing
February 2019

The application of keystone flap combined with vacuum-assisted closure in the repair of sacrococcygeal skin defect after tumor resection.

J Surg Oncol 2019 Feb 4. Epub 2019 Feb 4.

Department of Plastic Surgery, Changhai Hospital, Second Military Medical University, Shanghai, China.

Objective: We aimed to explore the efficacy of keystone flap combined with vacuum-assisted closure (VAC) in the repair of sacrococcygeal wounds.

Methods: This study is a retrospective review of patients undergoing keystone flap reconstruction between January 2014 and January 2018. A standardized data collection template was used to collect related variables. Read More

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http://dx.doi.org/10.1002/jso.25397DOI Listing
February 2019

Is EGFR really a therapeutic target in head and neck cancers?

J Surg Oncol 2019 Jan 30. Epub 2019 Jan 30.

Department of Head and Neck Oncology, HCG Cancer Centre, Bangalore, India.

Epidermal growth factor receptor (EGFR) is overexpressed in 90% to 100% of squamous cell carcinoma of the head and neck (SCCHN). The overexpression of EGFR and its ligand transforming growth factor is associated with poorer survival. EGFR inhibitors such as Cetuximab (Erbitux) have shown a significant antitumoral effect in SCCHN and has improved locoregional control and as well as survival. Read More

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http://doi.wiley.com/10.1002/jso.25387
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http://dx.doi.org/10.1002/jso.25387DOI Listing
January 2019
5 Reads

Retrospective analysis of variant venous anatomy in 303 laparoscopic adrenalectomies and its clinical implications.

J Surg Oncol 2019 Jan 30. Epub 2019 Jan 30.

Shanghai Key Laboratory for Endocrine Tumors, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of Chinese Health Ministry, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Background And Objectives: To clarify the correlation of variant venous anatomy with adrenal tumor phenotype and surgical outcomes.

Patients And Methods: This retrospective study included 303 consecutive minimally invasive adrenalectomies from 301 patients. All adrenal veins were identified. Read More

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http://doi.wiley.com/10.1002/jso.25364
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http://dx.doi.org/10.1002/jso.25364DOI Listing
January 2019
3 Reads

Stage-matched survival differences by ethnicity among gastric cancer patients of Asian ancestry treated in the United States.

J Surg Oncol 2019 Jan 29. Epub 2019 Jan 29.

Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, New York.

Background: Differences have been noted in overall survival (OS) in gastric cancer (GC) between trials conducted in Western vs Asian countries. The National Cancer Database (NCDB) reports outcomes and patient/disease variables relevant to OS.

Methods: Using NCDB, we identified 89 558 adult patients with GC diagnosed (2004-2012), where self-reported race/ethnicity was available. Read More

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http://dx.doi.org/10.1002/jso.25389DOI Listing
January 2019

Tissue sealants for the prevention of lymphoceles after radical inguinal lymph node dissection in patients with melanoma: A systematic review and individual patient data meta-analysis.

J Surg Oncol 2019 Jan 23. Epub 2019 Jan 23.

Department of Surgery, University Medical Center Mannheim, University of Heidelberg, Mannheim, Germany.

Background And Objectives: Postoperative lymphoceles and further wound complications occur frequently after radical inguinal lymph node dissection (ILND). In various studies, tissue sealants have shown to reduce the incidence of postoperative morbidity.

Methods: A systematic review and meta-analysis of randomized controlled trials (RCTs) investigating the effectiveness of tissue sealants in reducing the incidence of postoperative lymphoceles following ILND in patients with melanoma was conducted. Read More

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http://doi.wiley.com/10.1002/jso.25366
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http://dx.doi.org/10.1002/jso.25366DOI Listing
January 2019
8 Reads

Number of positive lymph nodes better predicts survival for oral cavity cancer.

J Surg Oncol 2019 Jan 23. Epub 2019 Jan 23.

Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

Background: We compared the predictive ability of our proposed N classification with that of the American Joint Committee on Cancer (AJCC) nodal (N) classification for oral cavity squamous cell carcinoma (OCC).

Methods: We assessed 345 OCC patients who underwent primary tumor extirpation and neck lymph node (LN) dissection. N classification was analyzed by recursive partitioning analysis and compared with the AJCC N classification by c-index. Read More

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http://dx.doi.org/10.1002/jso.25386DOI Listing
January 2019
1 Read

Commentary on "Number of positive lymph nodes better predicts survival for oral cavity cancer" by Hojun Lee et al.

J Surg Oncol 2019 Jan 23. Epub 2019 Jan 23.

Chair General Surgery, Nebraska Methodist Hospital, Omaha, Nebraska.

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http://dx.doi.org/10.1002/jso.25385DOI Listing
January 2019
1 Read

Surgical treatment of posterior mediastinal neurogenic tumors.

J Surg Oncol 2019 Jan 17. Epub 2019 Jan 17.

Department of Cardiothoracic Surgery, Huashan Hospital, Fudan University, Shanghai, China.

Background: Posterior mediastinal neurogenic tumors are among the most frequent mediastinal masses in adults. These tumors may be dumbbell shaped, extending into the spinal canal, exclusively paraspinal or apical tumors extending in the cervical region. In this report, we present our experience in the surgical resection of these tumors and discuss the surgical strategies for such tumors. Read More

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http://dx.doi.org/10.1002/jso.25381DOI Listing
January 2019
3 Reads

Financial toxicity in cancer care: Prevalence, causes, consequences, and reduction strategies.

J Surg Oncol 2019 Jan 16. Epub 2019 Jan 16.

Division of Hematology and Oncology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

Financial toxicity is the adverse impact of a cancer diagnosis on a patient's financial well-being resulting from direct or indirect costs. Potential consequences of financial toxicity include material loss, psychological distress, and/or maladaptive coping strategies. This review will summarize the prevalence, causes, and consequences of financial toxicity, with an emphasis on strategies to anticipate and reduce its burden. Read More

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http://dx.doi.org/10.1002/jso.25374DOI Listing
January 2019
1 Read

Signet ring cell features with peritoneal carcinomatosis in patients undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy are associated with poor overall survival.

J Surg Oncol 2019 Jan 16. Epub 2019 Jan 16.

Division of Surgical Oncology, Icahn School of Medicine at Mount Sinai, New York City, New York.

Background: Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) is effective in select patients with peritoneal carcinomatosis (PC). Signet ring cell (SRC) pathology is associated with poor prognosis. The role of CRS/HIPEC in this population is unclear. Read More

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http://dx.doi.org/10.1002/jso.25379DOI Listing
January 2019
2 Reads

Carnoy's solution fixation with compression significantly increases the number of lymph nodes yielded from colorectal cancer specimens.

J Surg Oncol 2019 Jan 16. Epub 2019 Jan 16.

Department of Surgery, Kaiser Permanente Southern California, San Diego, California.

Background And Objectives: Carnoy's fixation and compression represents a novel technique to enhance lymph node evaluation and accuracy of staging after colorectal cancer resection.

Methods: This study was performed in all adults undergoing colorectal cancer operations by Kaiser Permanente surgeons at two separate facilities. Patients were assigned to either location based upon surgeon and patient availability. Read More

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http://dx.doi.org/10.1002/jso.25372DOI Listing
January 2019

Correlation between serum prealbumin and prognosis of patients with hepatocellular carcinoma after hepatectomy.

J Surg Oncol 2019 Jan 15. Epub 2019 Jan 15.

Hepatobiliary Surgery Department, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, China.

Objective: To determine whether serum prealbumin levels are associated with long-term survival after hepatectomy in patients with primary hepatocellular carcinoma(HCC).

Methods: A consecutive sample of 526 patients with HCC who underwent potentially curative hepatectomy from August 2007 to August 2010 was retrospectively analyzed. Patients were classified as having normal or reduced serum prealbumin based on cut-off values of 200 or 182 mg/L. Read More

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http://dx.doi.org/10.1002/jso.25378DOI Listing
January 2019
2 Reads

Rare metastatic patterns after malignant transformation of serous borderline tumor of the ovary.

J Surg Oncol 2019 Jan 15. Epub 2019 Jan 15.

Division of Gynecologic Oncology, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida.

Serous borderline tumors are rare, benign ovarian neoplasms that may recur and undergo malignant transformation to low-grade serous carcinomas (LGSCs). In this report, a 50-year-old female with a remote history of a serous borderline ovarian tumor experienced a recurrence of LGSC, presenting as a large solitary subcutaneous mass anterior to the sternum after a 33-year disease-free interval. The described case highlights the unpredictable nature of this disease and the importance of implementing lifelong surveillance strategies. Read More

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http://dx.doi.org/10.1002/jso.25380DOI Listing
January 2019
2 Reads

Patients with in-transit melanoma metastases have comparable survival outcomes following isolated limb infusion or intralesional PV-10-A propensity score matched, single center study.

J Surg Oncol 2019 Jan 15. Epub 2019 Jan 15.

Queensland Melanoma Project, Princess Alexandra Hospital, Queensland Health, Brisbane, Queensland, Australia.

Background And Objective: Isolated limb infusion (ILI) and intralesional PV-10 are well described locoregional therapies for in-transit melanoma. The objective of this study was to assess the effect of these treatments on survival outcomes within a cohort matched for key characteristics.

Methods: Patients were treated using ILI or intralesional PV-10 at a single institution and the data prospectively recorded. Read More

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http://dx.doi.org/10.1002/jso.25373DOI Listing
January 2019
1 Read

Reconstructive limb-salvage surgery after lower extremity soft tissue sarcoma resection: A 20-year experience.

J Surg Oncol 2019 Jan 15. Epub 2019 Jan 15.

Department of Plastic and Reconstructive Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland.

Background: Reconstructive surgery is often required following lower extremity soft tissue sarcoma resection. The relationship between the method of plastic surgery reconstruction and postoperative wound healing or functional oncologic outcomes in this patient population is poorly understood.

Methods: We performed a retrospective review on all adult patients that underwent soft tissue reconstruction following resection of lower extremity soft tissue sarcomas between 1996 and 2016 at our institution. Read More

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http://dx.doi.org/10.1002/jso.25358DOI Listing
January 2019
1 Read

Impact of intramural and extramural vascular invasion on stage II-III colon cancer outcomes.

J Surg Oncol 2019 Jan 15. Epub 2019 Jan 15.

Department of General and Gastrointestinal Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

Background And Objectives: Vascular invasion, in particular extramural venous invasion (EMVI), is a pathologic characteristic that has been extensively studied in rectal cancer but rarely in colon cancer. This study aims to evaluate its prognostic role in stage II-III colon cancer.

Methods: All stage II-III colon cancer patients who underwent surgery between 2004 and 2015 were reviewed. Read More

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http://dx.doi.org/10.1002/jso.25367DOI Listing
January 2019
1 Read

Long-term follow-up of RET Y791F carriers in Denmark 1994-2017: A National Cohort Study.

J Surg Oncol 2019 Jan 15. Epub 2019 Jan 15.

Department of ORL, Head & Neck Surgery and Audiology, Odense University Hospital, Odense, Denmark.

Background And Objectives: Recently, a comprehensive study presented evidence that a long-disputed REarranged during Transfection (RET) variant, RET Y791F, should be classified as nonpathogenic. In spite of this, several subsequently published papers, including the revised American Thyroid Association guidelines for medullary thyroid carcinoma, refer to the variant as pathogenic. This study presents data from a unique national Danish cohort of RET Y791F carriers who have been followed by watchful waiting instead of being subjected to early thyroidectomy, to determine if any carrier shows evidence of multiple endocrine neoplasia 2A (MEN2A) at long-term follow-up. Read More

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http://doi.wiley.com/10.1002/jso.25371
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http://dx.doi.org/10.1002/jso.25371DOI Listing
January 2019
6 Reads

Ex vivo liver resection coupled with associated liver partition and portal vein ligation: Combining existing techniques to achieve surgical resectability.

J Surg Oncol 2019 Jan 15. Epub 2019 Jan 15.

Division of Hepatobiliary and Pancreatic Surgery, Atrium Health, Charlotte, North Carolina.

Incorporation of liver transplant techniques in hepatopancreaticobiliary surgery has created an opportunity for the resection of locally advanced hepatic tumors formerly considered unresectable. A 73-year-old woman presented with cholangiocarcinoma involving inferior vena cava, all three hepatic veins, and right anterior portal pedicle, initially deemed nonoperative. This case demonstrates the first combined application of associating liver partition and portal vein ligation for staged hepatectomy and ex vivo resection to perform an R0. Read More

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http://doi.wiley.com/10.1002/jso.25375
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http://dx.doi.org/10.1002/jso.25375DOI Listing
January 2019
5 Reads

Improved survival in rectal cancer patients who are treated with long-course versus short-course neoadjuvant radiotherapy: A propensity-matched analysis of the NCDB.

J Surg Oncol 2019 Jan 13. Epub 2019 Jan 13.

Department of Surgery, University of Colorado School of Medicine, Aurora, Colorado.

Background: Randomized controlled trials have demonstrated comparable survival outcomes for short-course (SCRT) and long-course neoadjuvant radiotherapy (LCRT) in patients with rectal cancer.

Methods: Using the National Cancer Data Base (2004-2015), a propensity score was used to match 188 patients with rectal cancer receiving SCRT to 376 patients receiving LCRT. Perioperative, oncologic, and survival outcomes were compared. Read More

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http://dx.doi.org/10.1002/jso.25355DOI Listing
January 2019
1 Read

Developing and validating a preoperative risk score to predict 90-day mortality after liver resection.

J Surg Oncol 2019 Jan 13. Epub 2019 Jan 13.

Deptartment of HPB and Liver Transplantation surgery, Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom.

Background: Hepatobiliary surgeons continue to expand the pool of patients undergoing liver resection using combinations of surgical and interventional procedures with chemotherapy. Improved perioperative care allows for operation on higher risk surgical patients. Postoperative outcomes, including 90-day mortality that improved over the past decade but still varies across cohorts. Read More

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http://doi.wiley.com/10.1002/jso.25350
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http://dx.doi.org/10.1002/jso.25350DOI Listing
January 2019
5 Reads
3.244 Impact Factor

Introduction: Melanoma seminar.

Authors:
Mary S Brady

J Surg Oncol 2019 Jan;119(2):167

Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.

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http://doi.wiley.com/10.1002/jso.25349
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http://dx.doi.org/10.1002/jso.25349DOI Listing
January 2019
6 Reads

Multimodality treatment of oligometastatic anal squamous cell carcinoma: A case series and literature review.

J Surg Oncol 2019 Jan 12. Epub 2019 Jan 12.

Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia.

Background And Objectives: There is limited evidence to guide the management of patients with oligometastatic anal squamous cell carcinoma (SCC). We aimed to address this question by reporting the outcome of SCC patients who were treated with organ-directed therapies at two large cancer centers.

Methods: Patients with advanced anal SCC who were treated with surgery, stereotactic radiotherapy, or radiofrequency ablation (RFA) with a curative intent from 2008 to 2017 were retrospectively identified from the institutional electronic patient records. Read More

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http://doi.wiley.com/10.1002/jso.25320
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http://dx.doi.org/10.1002/jso.25320DOI Listing
January 2019
6 Reads

Are BRCA1 and BRCA2 gene mutation patients underscreened for pancreatic adenocarcinoma?

J Surg Oncol 2019 Jan 12. Epub 2019 Jan 12.

Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana.

Background: Breast cancer (BRCA) mutations account for the highest proportion of hereditary causes of pancreatic ductal adenocarcinoma (PDAC). Screening is currently recommended only for patients with one first-degree relative or two family members with PDAC. We hypothesized that screening all BRCA1/2 patients would identify a higher rate of pancreatic abnormalities. Read More

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http://dx.doi.org/10.1002/jso.25376DOI Listing
January 2019
1 Read

Changes in high endothelial venules in lymph nodes after vascularized and nonvascularized lymph node transfer in a murine autograft model.

J Surg Oncol 2019 Jan 12. Epub 2019 Jan 12.

Department of Plastic and Reconstructive Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

Background And Objectives: Vascularized lymph node transfer (LNT) is gaining popularity in the treatment of lymphedema. However, it is unclear whether the vascularization of transferred lymph nodes (LNs) contributes to functional improvement. High endothelial venules (HEVs) are specialized vessels that allow lymphocytes to enter LNs. Read More

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http://dx.doi.org/10.1002/jso.25365DOI Listing
January 2019
4 Reads

Total pancreatectomy for pancreatic malignancy with preservation of the spleen.

J Surg Oncol 2019 Jan 12. Epub 2019 Jan 12.

Department of Pancreatic Surgery, Pancreatic Disease Institute, Huashan Hospital affiliated to Fudan University, Shanghai, China.

Background: Total pancreatectomy may be necessary to achieve margin-negative resection for pancreatic cancer. However, despite the desirability of saving the spleen, the feasibility, safety, and oncological outcomes of spleen-preserving total pancreatectomy have not been studied in patients with malignancy involving the pancreatic neck or proximal body. The aim of this study was to report the efficacy of spleen-preserving total pancreatectomy using the Warshaw technique for patients with pancreatic malignancies. Read More

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http://dx.doi.org/10.1002/jso.25377DOI Listing
January 2019
1 Read

A reflection on noninvasive molecular imaging of cancer spread to lymph nodes.

J Surg Oncol 2019 Jan 10. Epub 2019 Jan 10.

Second Department of General Surgery, Baoding No. 1 Central Hospital, Baoding, Hebei, China.

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http://doi.wiley.com/10.1002/jso.25357
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http://dx.doi.org/10.1002/jso.25357DOI Listing
January 2019
5 Reads

Establishing a center of excellence for hereditary diffuse gastric cancer syndrome.

J Surg Oncol 2019 Jan 7. Epub 2019 Jan 7.

Surgical Oncology Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

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http://doi.wiley.com/10.1002/jso.25363
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http://dx.doi.org/10.1002/jso.25363DOI Listing
January 2019
3 Reads

Comprehensive multimodal surgical treatment of end-stage lower extremity lymphedema with toe management: The combined Charles,' Homan's, and vascularized lymph node transfer (CHAHOVA) procedures.

J Surg Oncol 2019 Jan 6. Epub 2019 Jan 6.

Department of Plastic and Reconstructive Surgery, China Medical University Hospital, Taichung, Taiwan.

Background: End-stage lower extremity lymphedema (LEL) poses a particularly formidable challenge to surgeons as multiple pathological processes are at work. Because single modality treatment is often unsuccessful, we devised a comprehensive multimodal surgical treatment. The aim of this study is to share the technical considerations and examine the clinical outcomes of this combined approach. Read More

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http://dx.doi.org/10.1002/jso.25356DOI Listing
January 2019
4 Reads

Distal extremities soft tissue sarcomas: Are they so different from other limb localizations?

J Surg Oncol 2019 Jan 4. Epub 2019 Jan 4.

Faculté de Médecine de la Timone, Génétique Médicale et génomique fonctionnelle, UMR S910 Inserm, Université Aix-Marseille 2, Marseille, France.

Background And Objectives: Soft tissue sarcoma localization in distal extremities (DESTS) of the limbs (hand/fingers, and foot/toes) is unusual. The literature is scarce about their behavior and this study was designed to assess their epidemiological characteristics, outcomes, and prognosis compared to other limb localizations (OLSTS).

Methods: From 1980 to 2010, adult DESTS and OLSTS in 22 centers were included. Read More

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http://dx.doi.org/10.1002/jso.25359DOI Listing
January 2019
2 Reads

Combined double vascularized lymph node transfers and modified radical reduction with preservation of perforators for advanced stages of lymphedema.

J Surg Oncol 2019 Jan 4. Epub 2019 Jan 4.

Department of Plastic and Reconstructive Surgery, China Medical University, Taichung, Taiwan.

Background: Treatment of advanced lymphedema requires not only restoration of physiological lymph drainage, but also excision of fibrotic tissue and excess skin. The aim of this study is to show how the combination of double vascularized lymph node transfers (VLNTs) and a modified radical reduction with preservation of perforators (RRPP) can accomplish both of these treatment goals.

Methods: Between 2010 and 2016, 16 patients (15 female and one male) with extremity lymphedema underwent a combined double gastroepiploic VLNTs and modified RRPP. Read More

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http://dx.doi.org/10.1002/jso.25360DOI Listing
January 2019
3 Reads

Outcomes after hypofractionated stereotactic radiotherapy for colorectal cancer oligometastases.

J Surg Oncol 2019 Jan 4. Epub 2019 Jan 4.

Department of Radiation Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.

Background And Objectives: To assess the efficacy and the effect of biologic effective dose (BED) on outcomes treated by hypofractionated stereotactic radiotherapy for colorectal cancer (CRC) oligometastases.

Methods: Patients with CRC oligometastases treated at our hospital between 2009 and 2016 were included. The relationship between BED and risk of local recurrence was assessed. Read More

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http://dx.doi.org/10.1002/jso.25361DOI Listing
January 2019
5 Reads
3.244 Impact Factor