52,099 results match your criteria Journal of plastic reconstructive & aesthetic surgery : JPRAS[Journal]


A nomogram to predict osteoradionecrosis in oral cancer after marginal mandibulectomy and radiotherapy.

Laryngoscope 2019 Feb 20. Epub 2019 Feb 20.

Department of Otolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital, Kwei-Shan, Taiwan.

Objective: There is no useful tool to clinically predict the occurrence of osteoradionecrosis (ORN) of the mandible quantitatively. The aim was to investigate the risk factors, including different modalities of radiotherapy, for developing mandibular ORN in patients undergoing marginal mandibulectomy and postoperative radiotherapy.

Methods: Between January 2006 and December 2012, 167 subjects who underwent marginal mandibulectomy and postoperative radiotherapy with different modalities were enrolled. Read More

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http://dx.doi.org/10.1002/lary.27870DOI Listing
February 2019

Investigating the Need for Point-of-Care Robots to Support Teleconsultation.

Telemed J E Health 2019 Feb 20. Epub 2019 Feb 20.

1 College of Nursing, Seoul National University, Seoul, Republic of Korea.

Background: Development of a point-of-care (POC) consultation system based on telepresence robots is needed to enable effective decision-making by medical staff at care sites.

Introduction: This study aimed to identify essential features and functional requirements of teleconsultation robot systems and predict potential administrative and clinical issues.

Materials And Methods: Surveys were conducted with 90 health care professionals and additional focus group interviews with 4 physicians and 5 nurses. Read More

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https://www.liebertpub.com/doi/10.1089/tmj.2018.0255
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http://dx.doi.org/10.1089/tmj.2018.0255DOI Listing
February 2019
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Alkaloids from Nelumbinis Plumula (AFNP) ameliorate aortic remodeling via RhoA/ROCK pathway.

Biomed Pharmacother 2019 Feb 20;112:108651. Epub 2019 Feb 20.

Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, PR China; Fujian Key Laboratory of Integrative Medicine on Geriatrics, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, PR China. Electronic address:

The protective role of alkaloids from Nelumbinis Plumula (AFNP) on the aorta during hypertension is not yet fully understood. We hypothesize that AFNP exerts protective effects against Ang II-induced hypertension by mediating RhoA/ROCK pathway and phenotypic switching during hypertension. In the present study, we evaluated the effect of AFNP on angiotensin II (Ang II)-induced actin cytoskeleton reorganization and aorta remodeling, as well as the involvement of RhoA/Rho-associated coiled kinase (ROCK) pathway in protecting against hypertension. Read More

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http://dx.doi.org/10.1016/j.biopha.2019.108651DOI Listing
February 2019

Wound Coverage Options for Soft Tissue Defects Following Calcaneal Fracture Management (Operative/Surgical).

Clin Podiatr Med Surg 2019 Apr 12;36(2):323-337. Epub 2018 Dec 12.

Plastic Reconstructive and Orthopaedic Surgery, University of Pennsylvania Health System, Perelman Center for Advanced Medicine, 3400 Civic Center Boulevard, South Pavilion, 1st Floor, Philadelphia, PA 19104, USA.

Soft tissue defects and wound healing complications related to calcaneus fractures may result in significant morbidity. The management of these soft tissue complications requires following reconstructive principles that provide the requisites for preservation of the injured limb and the maximization of function. Soft tissue complications are addressed with methods that commensurate with the degree of injury, ranging from local wound care to free flap reconstruction. Read More

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http://dx.doi.org/10.1016/j.cpm.2018.10.012DOI Listing

The 1470 nm diode laser with an intralesional fiber device: a proposed solution for the treatment of inflamed and infected keloids.

Burns Trauma 2019 15;7. Epub 2019 Feb 15.

1Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, 639 Zhi Zao Ju Road, Shanghai, 200011 China.

Background: Keloids are the result of abnormal wound healing and often are subject to infections and recurrent inflammation. We present a study conducted with a 1470 nm diode laser using an intralesional optical fiber device for the treatment of inflamed keloid scars. We evaluate its efficacy as a novel alternative method to decrease keloid infection and inflammation. Read More

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http://dx.doi.org/10.1186/s41038-019-0143-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376646PMC
February 2019

Pros and cons of gastric bypass surgery in individuals with obesity and type 2 diabetes: nationwide, matched, observational cohort study.

BMJ Open 2019 Jan 15;9(1):e023882. Epub 2019 Jan 15.

Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden.

Objectives: Long-term effects of gastric bypass (GBP) surgery have been presented in observational and randomised studies, but there are only limited data for persons with obesity and type 2 diabetes mellitus (T2DM) regarding postoperative complications.

Design: This is a nationwide observational study based on two quality registers in Sweden (National Diabetes Register, NDR and Scandinavian Obesity Surgery Register, SOReg) and other national databases.

Setting: After merging the data, we matched individuals with T2DM who had undergone GBP with those not surgically treated for obesity on propensity score, based on sex, age, body mass index (BMI) and calendar time. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-023882DOI Listing
January 2019

Spatial and temporal changes of midface in Apert's syndrome.

J Plast Surg Hand Surg 2019 Feb 19:1-8. Epub 2019 Feb 19.

c Section of Plastic and Reconstructive Surgery , Yale School of Medicine , New Haven , CT , USA.

The dysplastic maxilla and retracted zygoma characterize Apert's syndrome. The relationship between the cranial base and facial development is believed to be influential and substantial. The purpose of this study is to explore the temporal relationships of maldevelopment of these structures to identify potential influence patterns. Read More

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http://dx.doi.org/10.1080/2000656X.2018.1541324DOI Listing
February 2019

Outcome of Body-Contouring Procedures After Massive Weight Loss.

Obes Surg 2019 Feb 18. Epub 2019 Feb 18.

Department of Hand, Plastic and Reconstructive Surgery, BG Trauma Center, Eberhard-Karls University of Tübingen, Schnarrenbergstr. 95, 72076, Tübingen, Germany.

Background: With the increased popularity of bariatric surgery, the demand for body-contouring procedures is growing. Associated with these procedures are a number of complications due to different risk factors and patients' characteristics. The aim of this study was to assess the outcome of body-contouring procedures and correlate it to possible risk factors. Read More

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http://dx.doi.org/10.1007/s11695-019-03773-zDOI Listing
February 2019

Enhancing the prognostic role of melanoma sentinel lymph nodes through microscopic tumour burden characterization: clinical usefulness in patients who do not undergo complete lymph node dissection.

Melanoma Res 2018 Jul 17. Epub 2018 Jul 17.

Department of Plastic and Reconstructive Surgery, Regional Melanoma Referral Center and Melanoma & Skin Cancer Unit.

This study aimed to investigate the sentinel lymph node (SLN) tumour burden to predict the non-SLN positivity rate and the survival of melanoma patients to evaluate whether SLN microstaging could predict the prognosis, similar to what is currently performed by examining the lymph nodes excised by complete lymph node dissection. Of 1130 consecutive melanoma patients who underwent SLN biopsy, 226 were tumour-positive and 204 were included in this study. SLN metastases were classified on the basis of dimensional (Rotterdam) and topographic (Dewar) criteria either separately or combined. Read More

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http://dx.doi.org/10.1097/CMR.0000000000000481DOI Listing

New developments in prosthetic arm systems.

Orthop Res Rev 2016 7;8:31-39. Epub 2016 Jul 7.

Christian Doppler Laboratory for Restoration of Extremity Function, Division of Plastic and Reconstructive Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria,

Absence of an upper limb leads to severe impairments in everyday life, which can further influence the social and mental state. For these reasons, early developments in cosmetic and body-driven prostheses date some centuries ago, and they have been evolving ever since. Following the end of the Second World War, rapid developments in technology resulted in powered myoelectric hand prosthetics. Read More

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http://dx.doi.org/10.2147/ORR.S71468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209370PMC

Cognitive Behavioral Therapy for Acute Post-trauma Distress: A Randomized, Controlled, Proof-of-Concept Study among Hospitalized Adults with Burns.

Arch Phys Med Rehabil 2019 Feb 15. Epub 2019 Feb 15.

Johns Hopkins Burn Center, Johns Hopkins Bayview Medical Center, Baltimore, MD; Department of Surgery, Division of Plastics and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.

Objective: (1) To evaluate the feasibility of conducting a randomized controlled trial (RCT) of the Safety, Meaning, Activation and Resilience Training (SMART) intervention versus Non-Directive Supportive Psychotherapy (NDSP) in an acutely hospitalized adult burn survivor sample; (2) To assess the preliminary impact of SMART on Acute Stress Disorder (ASD)/Posttraumatic Stress Disorder (PTSD) and Major Depress Disorder (MDD) symptom reduction as secondary prevention.

Design: Proof-of-concept, parallel group, RCT design.

Setting: Regional burn center. Read More

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http://dx.doi.org/10.1016/j.apmr.2018.11.027DOI Listing
February 2019

Imaging of pH and pO gives insight in molecular processes of irradiated cells.

Exp Dermatol 2019 Feb 18. Epub 2019 Feb 18.

Department of Otorhinolaryngology, Ludwig-Maximilians-University Munich, 81377, Munich, Germany.

One of the major challenges in radiation therapy is the interference with tissue repair processes due to hypoxic characteristics and pH dysregulation. In this study, we present dual imaging of pH and oxygenation in vitro based on luminescent biocompatible sensor foils that allow studying the effects of irradiation on different cell types in culture. Different sensitivities of fibroblast and oral squamous carcinoma cells were observed by complementing oxygen and pH differences with proliferation assays. Read More

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http://dx.doi.org/10.1111/exd.13905DOI Listing
February 2019

Chimeric vs composite flaps for mandible reconstruction.

Head Neck 2019 Feb 18. Epub 2019 Feb 18.

Section of Plastic and Reconstructive Surgery, Department of Surgery, University of Chicago Medical Center, Chicago, Illinois.

Background: Composite mandibular reconstruction requires multiple tissue components inset in different planes. Intrinsic chimeric flap design provides this, and may be best suited for these reconstructions.

Methods: A retrospective review of mandible reconstructions with composite, intrinsic chimeric, or 2 free flaps was performed. Read More

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http://dx.doi.org/10.1002/hed.25606DOI Listing
February 2019

Self-Healing and Injectable Hydrogel for Matching Skin Flap Regeneration.

Adv Sci (Weinh) 2019 Feb 16;6(3):1801555. Epub 2018 Nov 16.

Department of Plastic and Reconstructive Surgery Shanghai Ninth People's Hospital Shanghai JiaoTong University School of Medicine 639 Zhi Zao Ju Road Shanghai 200011 P. R. China.

The fabrication of highly biocompatible hydrogels with multiple unique healing abilities for the whole healing process, for example, multifunctional hydrogels with injectable, degradation, antibacterial, antihypoxic, and wound healing-promoting properties that match the dynamic healing process of skin flap regeneration, is currently a research challenge. Here, a multifunctional and dynamic coordinative polyethylene glycol (PEG) hydrogel with mangiferin liposomes (MF-Lip@PEG) is developed for clinical applications through Ag-S coordination of four-arm-PEG-SH and Ag. Compared to MF-PEG, MF-Lip@PEG exhibits self-healing properties, lower swelling percentages, and a longer endurance period. Read More

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http://dx.doi.org/10.1002/advs.201801555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364594PMC
February 2019

Fibroblast-myofibroblast crosstalk after exposure to mesenchymal stem cells secretome.

Gastroenterol Hepatol Bed Bench 2018 ;11(Suppl 1):S73-S79

Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Aim: The aim of the present study was to investigate the effect of human bone marrow-derived mesenchymal stem cells conditioned medium on fibroblast to myofibroblast differentiation.

Background: Mesenchymal stem cells have a long-term clinical application and widely have used in autoimmune disease and regenerative medicine. However, some MSCs derived cytokines such as TGF-β could have a dual role in suppression or progression of disease. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347993PMC
January 2018

Optimal management of scapholunate ligament injuries.

Orthop Res Rev 2018 6;10:41-54. Epub 2018 Aug 6.

Division of Plastic and Reconstructive Surgery, University of Florida College of Medicine, Gainesville, FL, USA,

Scapholunate ligament (SLL) injuries are a common cause of wrist pain and instability. Treatment of SLL injuries requires intricate understanding of wrist anatomy and biomechanics. Mindful physical exam and appropriate diagnostic studies can orient the surgeon to the defined stage of injury. Read More

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http://dx.doi.org/10.2147/ORR.S129620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209348PMC

Epilepsy, depression, and growth hormone.

Epilepsy Behav 2019 Feb 14. Epub 2019 Feb 14.

Clinical and Translational Science Center, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, United States of America.

Depression affects a large proportion of patients with epilepsy, and is likely due in part to biological mechanism. Hormonal dysregulation due to the disruptive effects of seizures and interictal epileptiform discharges on the hypothalamic-pituitary-adrenal axis likely contributes to high rates of depression in epilepsy. This paper reviews the largely unexplored role of neuroendocrine factors in epilepsy-related depression, focusing on Growth Hormone (GH). Read More

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http://dx.doi.org/10.1016/j.yebeh.2019.01.022DOI Listing
February 2019

Feasibility of direct promontory stimulation by bone conduction: A preliminary study of frequency-response characteristics in cats.

Hear Res 2019 Jan 23. Epub 2019 Jan 23.

ENT Institute, Eye & ENT Hospital of Fudan University, Fenyang Road 83, Shanghai, 200031, China; NHC Hearing Medicine Key Laboratory, Shanghai, China. Electronic address:

Background: As an alternative pathway to air conduction, bone conduction is a multipathway process that transmits sound energy to the inner ear through the skull in general. Based on this mechanism, bone conduction devices (BCDs) have been used widely in the rehabilitation of hearing loss. Although great efforts have been devoted to improving BCDs, drawbacks still exist in most categories of BCDs due to the complicated process of bone conduction. Read More

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http://dx.doi.org/10.1016/j.heares.2019.01.013DOI Listing
January 2019

AMORE treatment as salvage treatment in children and young adults with relapsed head-neck rhabdomyosarcoma.

Radiother Oncol 2019 Feb 17;131:21-26. Epub 2018 Dec 17.

Princess Máxima Centre for Paediatric Oncology, Utrecht, The Netherlands; Department of Paediatric Oncology, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, The Netherlands. Electronic address:

Background And Purpose: Survival after relapse of head and neck rhabdomyosarcoma (HNRMS) after prior external beam radiotherapy (EBRT) is poor, since options for adequate local treatment are often lacking. In this study we describe our experience with salvage AMORE in patients with relapsed HNRMS after prior EBRT.

Materials And Methods: Patients with relapsed HNRMS after prior EBRT in which salvage AMORE treatment was considered feasible were analysed; this includes patients with parameningeal, head and neck non-parameningeal and orbital localization. Read More

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http://dx.doi.org/10.1016/j.radonc.2018.10.036DOI Listing
February 2019

Critical Growth Processes for the Midfacial Morphogenesis in the Early Prenatal Period.

Cleft Palate Craniofac J 2019 Feb 17:1055665619827189. Epub 2019 Feb 17.

1 Department of Plastic and Reconstructive Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Background:: Congenital midfacial hypoplasia often requires intensive treatments and is a typical condition for the Binder phenotype and syndromic craniosynostosis. The growth trait of the midfacial skeleton during the early fetal period has been assumed to be critical for such an anomaly. However, previous embryological studies using 2-dimensional analyses and specimens during the late fetal period have not been sufficient to reveal it. Read More

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http://dx.doi.org/10.1177/1055665619827189DOI Listing
February 2019

Macroporous hydrogels derived from aqueous dynamic phase separation.

Biomaterials 2019 Apr 2;200:56-65. Epub 2019 Feb 2.

Tissue Engineering and Biofabrication Laboratory, Department of Health Sciences and Technology, ETH Zürich, Otto-Stern-Weg 7, 8093, Zürich, Switzerland. Electronic address:

A method to generate injectable macroporous hydrogels based on partitioning of polyethylene glycol (PEG) and high viscous polysaccharides is presented. Step growth polymerization of PEG was used to initiate a phase separation and the formation of a connected macroporous network with tunable dimensions. The possibilities and physical properties of this new category of materials were examined, and then applied to address some challenges in neural engineering. Read More

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http://dx.doi.org/10.1016/j.biomaterials.2019.01.047DOI Listing

Factors Leading to Decreased Rates of Immediate Postmastectomy Reconstruction.

J Surg Res 2019 Feb 14;238:207-217. Epub 2019 Feb 14.

Department of Surgery and Norris Comprehensive Cancer Center, Division of Breast, Soft Tissue and Endocrine Surgery, University of Southern California (USC), Los Angeles, California. Electronic address:

Background: This study was performed to determine if there was a difference in immediate breast reconstruction (IBR) rates between our public hospital and private cancer center, which share a common faculty with a consistent management philosophy in multidisciplinary care. We investigated the factors affecting postmastectomy reconstruction and IBR rates.

Materials And Methods: We retrospectively identified women with clinical stage I-II breast cancer who underwent mastectomy at our public hospital, Los Angeles County Medical Center, and our private cancer center, Keck Hospital of USC/Norris Comprehensive Cancer Center. Read More

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http://dx.doi.org/10.1016/j.jss.2019.01.010DOI Listing
February 2019

Evaluation of the eyebrow position after external Müller's muscle tucking: A new technique for ptosis repair.

J Plast Reconstr Aesthet Surg 2019 Jan 14. Epub 2019 Jan 14.

Department of Plastic and Reconstructive Surgery, Yokohama City University Hospital. 3-9 Fukuura, Kanazawa-ku, Yokohama-shi, Kanagawa 236-0004, Japan.

Eyebrow descent commonly occurs after ptosis repair or blepharoplasty surgery. The procedures used to correct acquired blepharoptosis are primarily classified into four groups. These procedures target the levator aponeurosis, Müller's muscle, both the aponeurosis and Müller's muscle, or the frontalis muscle. Read More

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http://dx.doi.org/10.1016/j.bjps.2019.01.010DOI Listing
January 2019

Endoscopic retrieval of retracted flexor tendons: An atraumatic technique.

J Plast Reconstr Aesthet Surg 2019 Jan 14. Epub 2019 Jan 14.

Faculty of Medicine, Department of Plastic, Reconstructive and Aesthetic Surgery, Hacettepe University, Sihhiye, 06080 Ankara, Turkey.

Background: The repair of retracted flexor tendons is a challenging problem for hand surgeons. The tendon stump should be handled in an atraumatic manner because any microtrauma to the sheath and tendon can lead to poor functional outcomes.

Methods: Twenty-three patients with flexor zone 2 injuries and intraoperative finding of retracted tendons were randomly divided into two groups: endoscopic retrieval group and proximal incision group. Read More

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http://dx.doi.org/10.1016/j.bjps.2019.01.007DOI Listing
January 2019

Recurrent and persistent carpal tunnel syndrome: predicting clinical outcome of revision surgery.

J Neurosurg 2019 Feb 15:1-9. Epub 2019 Feb 15.

1Department of Plastic & Reconstructive Surgery, Radboud University Medical Center, Nijmegen.

OBJECTIVEThe aim of this study was to evaluate the self-reported outcome of revision surgery in patients with recurrent and persistent carpal tunnel syndrome (CTS) and to identify predictors of clinical outcome of revision surgery.METHODSA total of 114 hands in 112 patients were surgically treated for recurrent and persistent CTS in one of 10 specialized hand clinics. As part of routine care, patients were asked to complete online questionnaires regarding demographic data, comorbidities, and clinical severity measures. Read More

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http://dx.doi.org/10.3171/2018.11.JNS182598DOI Listing
February 2019

Parry-Romberg syndrome treatment with fat transfer and a new bleaching formula.

J Cosmet Dermatol 2019 Feb 15. Epub 2019 Feb 15.

ISAPS, Athens, Greece.

Parry-Romberg syndrome is a hemifacial atrophy which can be complicated by melasma. We present two cases of Parry-Romberg syndrome, treated by fat transfer and bleaching of the skin using a modified "Kligman's formula." The atrophy, as well as the skin dyschromia, improved, and the results were stable. Read More

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http://dx.doi.org/10.1111/jocd.12819DOI Listing
February 2019

Treatment of neurotrophic keratopathy with minimally invasive corneal neurotisation: long-term clinical outcomes and evidence of corneal reinnervation.

Br J Ophthalmol 2019 Feb 15. Epub 2019 Feb 15.

Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

Aim: To report clinical outcomes and evidence of corneal innervation in patients with neurotrophic keratopathy (NK) treated with minimally invasive corneal neurotisation (MICN) using a sural nerve graft and donor sensory nerves from the face.

Methods: Patients undergoing MICN at The Hospital for Sick Children, Toronto, Canada were prospectively recruited. Data on central corneal sensation (CCS, measured with Cochet-Bonnet aesthesiometer), best-corrected visual acuity (BCVA) and corneal epithelial integrity were collected. Read More

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http://dx.doi.org/10.1136/bjophthalmol-2018-313042DOI Listing
February 2019

Free tissue transfer with the free rectus abdominis flap in high-risk patients above 65 years: A retrospective cohort study.

J Plast Reconstr Aesthet Surg 2019 Jan 11. Epub 2019 Jan 11.

Department of Hand, Plastic and Reconstructive Surgery, Burn Center, BG Trauma Center Ludwigshafen, Hand and Plastic Surgery, University of Heidelberg, Ludwig-Guttmann-Strasse 13, 67071 Heidelberg, Germany. Electronic address:

Background: Though technically feasible, free tissue transfer carries the risk of perioperative morbidity and mortality in elderly patients. To minimize the operative treatment time and complication rates, we choose the rectus abdominis muscle (RAM) flap.

Methods: Between 2012 and 2017, 34 patients (mean age: 74±7 years, range: 65-89 years) with comorbidities underwent defect reconstruction with a free RAM flap. Read More

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http://dx.doi.org/10.1016/j.bjps.2019.01.005DOI Listing
January 2019

National Patterns in Surgical Management of Syndactyly: A Review of 956 Cases.

Hand (N Y) 2019 Feb 15:1558944719828003. Epub 2019 Feb 15.

1 Yale University School of Medicine, New Haven, CT, USA.

Purpose: Being one of the most common congenital hand malformations, syndactyly is repaired by orthopedic, plastic, and fellowship-trained general surgeons. Limited multi-institutional outcomes analyses regarding incidence, timing, and type of repair exist.

Methods: All syndactyly cases performed over a 5-year period from 2012-2016 were isolated from the National Surgical Quality Improvement Program Pediatric database. Read More

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http://dx.doi.org/10.1177/1558944719828003DOI Listing
February 2019

Quality of teamwork in multidisciplinary cancer team meetings: A feasibility study.

PLoS One 2019 15;14(2):e0212556. Epub 2019 Feb 15.

Research Unit for Safety in Health, c/o Division of Plastic, Aesthetic and Reconstructive Surgery, Department of Surgery, Medical University of Graz, Graz, Austria.

Background: Tumor boards (TB) play an important role to formulate a management plan for the treatment of patients with a malignancy. Recent evidence suggests that optimally functioning teams (teamwork, communication and decision making) are major prerequisites to conduct efficient TB meetings. The aims of this study were i) to use a readily published tool as a template for the development of a teamwork perspective extended assessment tool and ii) to evaluate the tool in a feasibility study by clinical and non-clinical observers. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212556PLOS
February 2019

The First Reported Case of Gluteal Implant-Associated Anaplastic Large Cell Lymphoma (ALCL).

Aesthet Surg J 2019 Feb 15. Epub 2019 Feb 15.

Keck Hospital of University of Southern California, Los Angeles, CA.

Anaplastic large-cell lymphoma (ALCL) is a very rare but life-threatening complication that has largely been demonstrated to be associated with breast implants (BIA-ALCL). Patients are at risk of BIA-ALCL with the placement of breast implants for either cosmetic or reconstructive purposes, with the highest risks associated with textured breast implants. In the past decade, there have been an increasing number of publications focused on BIA-ALCL, but there has yet to be a reported case outside of the breast. Read More

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http://dx.doi.org/10.1093/asj/sjz044DOI Listing
February 2019
1 Read

A Meta-Analysis of Complication Rates Among Different SMAS Facelift Techniques.

Aesthet Surg J 2019 Feb 15. Epub 2019 Feb 15.

North Charleston, SC.

Background: Sub-SMAS rhytidectomy techniques are considered to have a higher complication profile, especially for facial nerve injury, when compared to less invasive SMAS techniques. This results in surgeons avoiding sub-SMAS dissection.

Objective: Aggregate and summarize data on complications among different SMAS facelift techniques. Read More

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https://academic.oup.com/asj/advance-article/doi/10.1093/asj
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http://dx.doi.org/10.1093/asj/sjz045DOI Listing
February 2019
3 Reads

Buccal Fat Pad Excision: Hydrodissection Technique.

Aesthet Surg J 2019 Feb 15. Epub 2019 Feb 15.

Department of Plastic and Reconstructive Surgery, Hospital General Dr. Ruben Leñero, Mexico City, Mexico.

Background: Buccal fat pad excision is a procedure in which the fat pad is extracted in order to achieve a more youthful appearance.

Objectives: To describe an alternative technique that utilizes hydrodissection as a means to extract the buccal fat pad.

Methods: This is a controlled, prospective, randomized clinical study with two groups. Read More

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http://dx.doi.org/10.1093/asj/sjz040DOI Listing
February 2019

Impregnated acetate gauze compared with lipido-colloid contact layer at dressing removal pain: a single-blind cross-over randomised control trial.

J Wound Care 2019 Feb;28(2):89-101

Dermatologist; Dermatology and out-patients consultations, Hôpital Dupuytren, Limoges, France.

Objective:: To evaluate the performance of Jelonet Plus (JP) and UrgoTul (UT), assessing pain at dressing removal when managing acute or chronic wounds at granulation and epithelialisation stages.

Methods:: This was a randomised, multicentre, controlled single-blinded study using a cross-over design. Hospitalised and ambulatory patients presenting with non-infected acute or chronic wounds (at least 40% of wound area of ≤100cm covered with granulation tissue) were randomly allocated to be treated with either JP or UT dressings applied according to a standardised local care procedure for two days. Read More

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http://dx.doi.org/10.12968/jowc.2019.28.2.89DOI Listing
February 2019

Pentraxin-3: A new parameter in predicting the severity of diabetic foot infection?

Int Wound J 2019 Feb 15. Epub 2019 Feb 15.

Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Firat University, Elazig, Turkey.

This study was undertaken to evaluate the diagnostic and prognostic values of pentraxin-3 (PTX-3) in patients with infected diabetic foot ulcers (IDFU) as well as to assess the association between PTX-3 levels and IDFU severity. This study included 60 IDFU patients (Group 1), 45 diabetic patients without DFU (Group 2), and 45 healthy controls. Patients with IDFU were divided into mild, moderate, and severe subgroups based on classification of clinical severity. Read More

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http://dx.doi.org/10.1111/iwj.13075DOI Listing
February 2019
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On the diagnosis and treatment of cutaneous and soft tissue tumours misdiagnosed as scars: Lessons from four cases.

Int Wound J 2019 Feb 15. Epub 2019 Feb 15.

Oncoplastic Surgery Subspecialty, Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Some types of skin and soft tissue tumours may be misdiagnosed as scars because of the scar-like manifestation or the history of injury. It is generally believed that injuries will activate wound healing, ultimately ending in fibrosis. Because of the tumour-promoting properties of both the microenvironment of the wound and the wound-healing process that may go awry, there is a likelihood that injuries may trigger tumour growth. Read More

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http://dx.doi.org/10.1111/iwj.13099DOI Listing
February 2019
2.023 Impact Factor

Lymphatic supermicrosurgery for the treatment of recurrent lymphocele and severe lymphorrhea.

Microsurgery 2019 Feb 14. Epub 2019 Feb 14.

International Lymphedema Center, Hiroshima University Hospital, Hiroshima, Japan.

Background: Lymphocele and lymphorrhea are frequent complications after lymph node excision. Recurrent lymphoceles and intractable lymphorrhea are particularly difficult to treat conservatively. We describe the outcomes of four patients with recurrent lymphocele and nine patients with persistent lymphorrhea that were treated by supermicrosurgery. Read More

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http://dx.doi.org/10.1002/micr.30435DOI Listing
February 2019
1 Read

The use of an acellular matrix derived from human dermis for the treatment of full-thickness skin wounds.

Cell Tissue Bank 2019 Feb 14. Epub 2019 Feb 14.

Burns Centre and Emilia Romagna Regional Skin Bank, "Bufalini" Hospital, AUSL Romagna, Cesena, Italy.

Full-thickness skin wounds occur in many different clinical cases and the use of biological acellular dermal matrices (ADMs) to reconstruct the damaged area is increasing in the field of plastic and reconstructive surgery. In particular, the ability of ADMs to maintain the structural properties of extracellular matrix as well as to provide a suitable environment for cell growth makes their use suitable for the improvement of wound healing and the reduction of side effects deriving from contracture and scar tissue formation. In this study, we describe the clinical use of a recently developed human dermal matrix (HDM) in combination with graft skin as an alternative reconstructive solution for the treatment of full-thickness skin wounds. Read More

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http://dx.doi.org/10.1007/s10561-019-09755-wDOI Listing
February 2019

The Relationship Between the Preoperative Neutrophil-to-Lymphocyte Ratio and Postoperative Nausea and Vomiting in Patients Undergoing Septorhinoplasty Surgery.

Aesthetic Plast Surg 2019 Feb 14. Epub 2019 Feb 14.

Department of Anaesthesiology and Reanimation, Fırat University School of Medicine, Elazig, Turkey.

Background: Postoperative nausea and vomiting (PONV) is one of the most common complications during the postoperative period. In the literature, there are many factors associated with PONV risk, but it is claimed that inflammation increases this risk. The neutrophil-to-lymphocyte ratio (NLR) is a cheap parameter to use in the diagnosis and follow-up of systemic inflammatory diseases. Read More

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http://dx.doi.org/10.1007/s00266-019-01325-5DOI Listing
February 2019

Mediators of Inflammation in Topical Therapy of Skin Cancers.

Mediators Inflamm 2019 10;2019:8369690. Epub 2019 Jan 10.

Carol Davila University of Medicine and Pharmacy Bucharest, Romania, Bucharest, Romania.

Taking into consideration that the immune system plays a very important role in the development of melanoma and non-melanoma skin cancers, which have a high prevalence in immunosuppressed patients and after prolonged ultraviolet radiation, the interest in developing novel therapies, in particular targeting the inflammation in cancer, has increased in the past years. The latest data suggest that therapies such as imiquimod (IMQ), ingenol mebutate (IM), 5-fluorouracil (5-FU), retinoids, and nonsteroidal anti-inflammatory drugs (NSAIDs) have been used with success in the topical treatment of some cancers. Herein, we review the topical treatment targeting the inflammation in skin cancer and the mechanisms involved in these processes. Read More

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https://www.hindawi.com/journals/mi/2019/8369690/
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http://dx.doi.org/10.1155/2019/8369690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350587PMC
January 2019
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Emerging nonsurgical and surgical techniques to treat erectile dysfunction: A systematic review of treatment options and published outcomes.

J Plast Reconstr Aesthet Surg 2018 Dec 26. Epub 2018 Dec 26.

Department of Plastic and Reconstructive Surgery, University of Southern California, Keck Hospital of USC, 1510 San Pablo Street, Suite 4000, Los Angeles, CA 90033, United States. Electronic address:

Erectile dysfunction (ED) is one of the most common causes of morbidity in male patients, with a prevalence of 50-60% in men aged 40-70 years. EDs may be caused by physical or psychological trauma, the former of which may be treatable through surgical intervention. Physical trauma may be further categorized as vasculogenic, neurogenic, or idiopathic in nature. Read More

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http://dx.doi.org/10.1016/j.bjps.2018.12.028DOI Listing
December 2018
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Neurosurgical and Scalp Reconstructive Challenges During Craniotomy in the Setting of Cutis Verticis Gyrata.

World Neurosurg 2019 Feb 11. Epub 2019 Feb 11.

Department of Neurosurgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA. Electronic address:

Cutis verticis gyrata (CVG) is a rare condition of the scalp in which thickening of the dermis induces rigid folds and furrows resembling the cerebral cortex. Two forms of primary CVG exist, essential in which CVG is the only presenting problem and non-essential in which the scalp condition occurs along with neuropsychiatric ailments. CVG can also occur secondary to a variety of causes including inflammatory, neoplastic, and metabolic conditions or drug use. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.217DOI Listing
February 2019

S2k Guidelines for Cutaneous Basal Cell Carcinoma - Part 2: Treatment, Prevention and Follow-up.

J Dtsch Dermatol Ges 2019 Feb;17(2):214-230

Department of Dermatology, Mainz University Medical Center, Mainz, Germany.

Basal cell carcinoma (BCC) is the most common malignant tumor among fair-skinned individuals, and its incidence had been steadily rising in the past decades. In order to maintain the highest quality of patient care possible, the German S2k guidelines were updated following a systematic literature search and with the participation of all professional societies and associations involved in the management of the disease. Part 2 addresses issues such as proper risk stratification, the various therapeutic approaches, and prevention as well as follow-up of patients with basal cell carcinoma. Read More

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http://doi.wiley.com/10.1111/ddg.13755
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http://dx.doi.org/10.1111/ddg.13755DOI Listing
February 2019
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Kinematic Analysis of the Distal Radioulnar Joint in Asymptomatic Wrists Using 4-Dimensional Computed Tomography-Motion Pattern and Interreader Reliability.

J Comput Assist Tomogr 2019 Feb 11. Epub 2019 Feb 11.

Department of Plastic and Reconstructive Surgery, Johns Hopkins University, Baltimore, MD.

Purpose: The aim of this study was to determine the normal measurement values and interobserver performance of the distal radioulnar joint during wrist pronation-supination using 4-dimensional computed tomography (CT).

Methods: Four-dimensional CT examinations were performed on the asymptomatic contralateral wrists of 10 patients with unilateral chronic wrist pain. Measurements were conducted using the modified radioulnar (mRU) line and epicenter (Epi) methods. Read More

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http://dx.doi.org/10.1097/RCT.0000000000000839DOI Listing
February 2019

Fracture of the Sesamoid Bone of the Thumb: A Case Report and Review of the Literature.

JBJS Case Connect 2019 Feb 13. Epub 2019 Feb 13.

Department of Plastic, Reconstructive and Hand Surgery, University Medical Center Utrecht, Utrecht, the Netherlands.

Case: Fracture of a sesamoid bone of the thumb is rare. We report a case of such a fracture after hyperextension of the thumb in a 26-year-old woman. After a volar plate injury was excluded, she was treated nonoperatively with 5 weeks of immobilization followed by physical therapy. Read More

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http://dx.doi.org/10.2106/JBJS.CC.18.00147DOI Listing
February 2019

Antibiotic elution and compressive strength of gentamicin/vancomycin loaded bone cements are considerably influenced by immersion fluid volume.

J Mater Sci Mater Med 2019 Feb 14;30(2):29. Epub 2019 Feb 14.

Julius-Maximilians University Wuerzburg, Department of Orthopaedic Surgery, Koenig-Ludwig-Haus, 11 Brettreichstrasse, D-97074, Wuerzburg, Germany.

The effect of doubling the immersion fluid (eluate) volume on antibiotic concentrations and on mechanical stability from vancomycin and gentamicin loaded bone cements was investigated in vitro. Antibiotic loaded bone cements containing premixed 1.34% gentamicin antibiotic concentration in the cement powder (wt), premixed 1. Read More

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http://dx.doi.org/10.1007/s10856-019-6229-7DOI Listing
February 2019

Long-term functional and esthetic outcomes after fibula free flap reconstruction of the mandible.

Head Neck 2019 Feb 13. Epub 2019 Feb 13.

Head and Neck Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.

Background: The goal of this study is to report functional and esthetic outcomes, after fibula free flap (FFF) reconstruction of the mandible for oral cancer, assessed by physicians, nonclinicians, and patients.

Methods: Twenty-five long-term survivors from oral cancer after FFF reconstruction were recalled for head and neck examination by surgeons, for photographs and patient-reported outcomes, using EORTC, QLQ-C30, H&N35, and FACE-Q questionnaires.

Results: Physicians reported 64% restoration of functionality compared to normal. Read More

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http://dx.doi.org/10.1002/hed.25666DOI Listing
February 2019

Towards functional restoration for persons with limb amputation: A dual-stage implementation of regenerative agonist-antagonist myoneural interfaces.

Sci Rep 2019 Feb 13;9(1):1981. Epub 2019 Feb 13.

Center for Extreme Bionics, MIT Media Lab, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.

While amputation has traditionally been viewed as a failure of therapy, recent developments in amputation surgery and neural interfacing demonstrate improved functionality and bidirectional communication with prosthetic devices. The agonist antagonist myoneural interface (AMI) is one such bi-directional neural communication model comprised of two muscles, an agonist and an antagonist, surgically connected in series within the amputated residuum such that contraction of one muscle stretches the other. By preserving agonist-antagonist muscle dynamics, the AMI allows proprioceptive signals from mechanoreceptors within both muscles to be communicated to the central nervous system. Read More

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http://dx.doi.org/10.1038/s41598-018-38096-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374452PMC
February 2019

Increase of glandular epithelial cell clusters by an external volume expansion device promotes adipose tissue regeneration by recruiting macrophages.

Biosci Rep 2019 Feb 13. Epub 2019 Feb 13.

Department of Plastic and Reconstructive Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China

Background: There is a clinical need for the use of engineered adipose tissue in place of surgical reconstruction. We previously found that the external volume expansion (EVE) device increased special cell clusters in well-vascularized connective stroma during adipose regeneration. However, the origin of these cell clusters and their role in adipose tissue regeneration remains unknown. Read More

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http://dx.doi.org/10.1042/BSR20181776DOI Listing
February 2019

LRG-1 promotes pancreatic cancer growth and metastasis via modulation of the EGFR/p38 signaling.

J Exp Clin Cancer Res 2019 Feb 13;38(1):75. Epub 2019 Feb 13.

Department of Pancreatic Surgery, Huashan Hospital, Fudan University, 12 Central Urumqi Road, Shanghai, 200040, China.

Background: The abnormal expression of leucine-rich-alpha-2-glycoprotein 1 (LRG-1) is reported to be associated with multiple malignancies, but its role in the progression of pancreatic ductal adenocarcinoma (PDAC) remains to be determined.

Methods: The expression of LRG-1 was assessed in PDAC tissues by RT-PCR, Western blot and immunohistochemistry. LRG-1-silenced or overexpressed cell lines were constructed using shRNA or LRG-1-overexpressing plasmids. Read More

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https://jeccr.biomedcentral.com/articles/10.1186/s13046-019-
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http://dx.doi.org/10.1186/s13046-019-1088-0DOI Listing
February 2019
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