1,196 results match your criteria Journal of oral science[Journal]


The level of salivary lactate dehydrogenase as an indicator of the association between gingivitis and related factors in Japanese university students.

J Oral Sci 2019 Feb 26. Epub 2019 Feb 26.

Department of Preventive Dentistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.

The aim of this study was to investigate the association between the presence of gingivitis estimated using the salivary level of lactate dehydrogenase (LD) and related factors in young Japanese adults. Data from 1,915 participants (21.4 ± 2. Read More

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http://dx.doi.org/10.2334/josnusd.18-0038DOI Listing
February 2019

Influence of water aging on surface hardness of low-shrinkage light-cured composite resins.

J Oral Sci 2019 Feb 26. Epub 2019 Feb 26.

School and Hospital of Stomatology, Jilin University.

This study evaluated the microhardness of four types of low-shrinkage composite resins and two types of universal composite resins with either 12 or 16 J/cm light power energy. Three disks were made for each group (n = 3) for a total of 36 specimens. The specimens were prepared by condensing the composite resin into a circular copper mold (diameter: 6 mm; height: 2 mm) and polymerizing with 700 mW/cm light power density. Read More

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http://dx.doi.org/10.2334/josnusd.17-0492DOI Listing
February 2019

Cone-beam computed tomography performance in measuring periodontal bone loss.

J Oral Sci 2019 Feb 26. Epub 2019 Feb 26.

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University.

The present study aimed to evaluate the performance of cone-beam computed tomography (CBCT) in assessing periodontal bone loss. If effective, CBCT could potentially be a more comfortable and accurate way to evaluate this disease. One hundred and eighty tooth sites from 13 patients were included. Read More

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http://dx.doi.org/10.2334/josnusd.17-0332DOI Listing
February 2019

Long-term effectiveness of arthrocentesis with and without hyaluronic acid injection for treatment of temporomandibular joint osteoarthritis.

J Oral Sci 2019 Feb 28. Epub 2019 Feb 28.

Department of Oral Surgery and Oral Medicine, Faculty of Dentistry, University of Oslo.

This study evaluated the long-term effectiveness of intra-articular temporomandibular joint arthrocentesis for patients with osteoarthritis and compared arthrocentesis/lavage alone with arthrocentesis/lavage and injected hyaluronic acid. Forty patients met the inclusion criteria, and 37 completed long-term follow-up (approximately 4 years). The patients were randomly allocated to two groups: arthrocentesis with lavage alone (A-group, n = 17) or combined with hyaluronic acid treatment (AS-group, n = 20). Read More

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http://dx.doi.org/10.2334/josnusd.17-0423DOI Listing
February 2019

Prolonged release of iloprost enhances pulpal blood flow and dentin bridge formation in a rat model of mechanical tooth pulp exposure.

J Oral Sci 2019 Feb 13. Epub 2019 Feb 13.

Excellence Center in Regenerative Dentistry, Faculty of Dentistry, Chulalongkorn University.

The aim of this study was to investigate the effect of prolonged release of iloprost, a prostacyclin analog, on angiogenesis and dental pulp healing in a rat model of mechanical pulp exposure. The profile of iloprost release from poly (lactic-co-glycolic) acid (PLGA) microspheres was evaluated, and expression of vascular endothelial growth factor (VEGF) mRNA was determined. The molars of rats were subjected to mechanical pulp exposure and 5 different forms of treatment: Ca(OH), PLGA (blank), iloprost, and iloprost/PLGA. Read More

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http://dx.doi.org/10.2334/josnusd.17-0368DOI Listing
February 2019
1 Read

In vivo antimicrobial activity of silver diammine fluoride on carious lesions in dentin.

J Oral Sci 2019 Feb 6. Epub 2019 Feb 6.

Department of General Dental Practice, Faculty of Dentistry, Kuwait University.

Minimally invasive treatment protocols may leave a residual layer of carious dentin, which requires treatment for the inhibition of bacterial growth beneath restorations. We aimed to examine the in vivo effect of silver diammine fluoride (SDF) and SDF + potassium iodide (KI) application on bacteria present in deep carious lesions. We studied the in vivo efficacy in five patients, each of which had five carious lesions. Read More

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http://dx.doi.org/10.2334/josnusd.17-0366DOI Listing
February 2019
1 Read

Deionized water can substitute common bleaching agents for nonvital tooth bleaching when treated with non-thermal atmospheric plasma.

J Oral Sci 2019 Feb 1. Epub 2019 Feb 1.

Department of Biomedical Engineering, İzmir Katip Çelebi University.

The bleaching efficacy of common bleaching agents and deionized water treated with non-thermal atmospheric pressure plasma in the pulp chamber for nonvital tooth bleaching was evaluated. A total of 120 extracted human maxillary first incisors were stained using human blood. Teeth were randomly divided into eight groups (n = 15). Read More

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http://dx.doi.org/10.2334/josnusd.17-0419DOI Listing
February 2019
6 Reads

Shaping effectiveness and surface topography of reciprocating files after multiple simulated uses.

J Oral Sci 2019 Feb 1. Epub 2019 Feb 1.

Department of Endodontics and Restorative Dentistry, University of Siena.

This in vitro study assessed morphological changes and efficiency of reciprocating files after multiple uses. Sixty standardized Endo Training Blocks and 10 ReciprocR25 files were selected (six blocks for each file). Each file was its own control (before use vs. Read More

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http://dx.doi.org/10.2334/josnusd.17-0311DOI Listing
February 2019

Molecular biological and histological effects of Er:YAG laser irradiation on tooth movement.

J Oral Sci 2019 Feb 1. Epub 2019 Feb 1.

Department of Orthodontics, Division of Oral Health and Development, Hiroshima University Hospital.

The aim of this study was to evaluate the effects of a fiberotomy-like procedure using Er:YAG laser irradiation on the velocity of orthodontic tooth movement. To produce experimental tooth movement in rats, orthodontic force was applied to the upper first molars with a nickel-titanium closed coil. The right molars were irradiated with an Er:YAG laser while the non-irradiated left molars were used as controls. Read More

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http://dx.doi.org/10.2334/josnusd.17-0472DOI Listing
February 2019
5 Reads

Effect of mechanical strain-induced PGE production on bone nodule formation by rat calvarial progenitor cells.

J Oral Sci 2019 Feb 1. Epub 2019 Feb 1.

Department of Orthodontics, Nihon University School of Dentistry.

High-magnitude mechanical strain inhibits bone nodule formation by reducing expression of bone morphogenetic protein-2 (BMP-2), Runt-related transcription factor 2 (Runx2), and muscle segment homeobox 2 (Msx2). Mechanical strain also induces production of proinflammatory factor prostaglandin E (PGE) by osteoblasts. We measured the effect of mechanical strain-induced PGE production on bone nodule formation and expression levels of bone formation-related factors. Read More

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https://www.jstage.jst.go.jp/article/josnusd/advpub/0/advpub
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http://dx.doi.org/10.2334/josnusd.18-0001DOI Listing
February 2019
4 Reads

Preoperative imaging findings as predictors of postoperative inferior alveolar nerve injury following mandibular cyst surgery.

J Oral Sci 2018 ;60(4):618-625

Maxillofacial Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University.

The purpose of the present study was to predict inferior alveolar nerve (IAN) exposure and associated neurosensory deficits after mandibular cyst surgery based on imaging findings. The study includes 193 sites in 184 consecutive patients who underwent enucleation of cystic lesions around a mandibular third molar (MM3) and extraction of the associated MM3. Absence/presence of white lines on panoramic radiographs (PR) and absence/presence of cortication surrounding the mandibular canal on computed tomography (CT) are evaluated as predictor variables. Read More

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http://dx.doi.org/10.2334/josnusd.17-0458DOI Listing
January 2018
1 Read

Type of dental visit and number of remaining teeth in Japanese elders.

J Oral Sci 2018 ;60(4):611-617

Mie Dental Association.

The aim of this study was to examine the association between type of dental visit and number of remaining teeth in Japanese elders. Data were collected from 3,163 adults aged 75 or 80 years who underwent an oral health examination. Type of dental visit was classified into four categories by treatment(s) received (none, periodontal, caries, or other treatment). Read More

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http://dx.doi.org/10.2334/josnusd.17-0335DOI Listing
January 2018
1 Read

Effects of interleukin-1β on human follicular dendritic cell-secreted protein gene expression in periodontal ligament cells.

J Oral Sci 2018 ;60(4):601-610

Department of Periodontology, Nihon University School of Dentistry at Matsudo.

Follicular dendritic cell-secreted protein (FDC-SP) is expressed in FDCs, human periodontal ligament (HPL) cells, and junctional epithelium. To evaluate the effects of interleukin-1 beta (IL-1β) on FDC-SP gene expression in immortalized HPL cells, FDC-SP mRNA and protein levels in HPL cells following stimulation by IL-1β were measured by real-time polymerase chain reaction and Western blotting. Luciferase (LUC), gel mobility shift, and chromatin immunoprecipitation (ChIP) analyses were performed to study the interaction between transcription factors and promoter regions in the human FDC-SP gene. Read More

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https://www.jstage.jst.go.jp/article/josnusd/60/4/60_17-0473
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http://dx.doi.org/10.2334/josnusd.17-0473DOI Listing
January 2018
8 Reads

Distribution of aquaporin-5, transforming growth factor-β and laminin during regeneration of atrophic rat submandibular glands after duct ligation.

J Oral Sci 2018 ;60(4):595-600

Department of Clinical Medicine, Nihon University School of Dentistry.

The aim of this study was to determine the localization of aquaporin-5 (AQP5), transforming growth factor-β (TGF-β) and laminin during regeneration of the rat submandibular gland. After duct ligation for 7 days, the regenerating glands were collected on days 0, 1, 3, 7, and 14 after ligation release to study the process of regeneration. Immunohistochemical staining revealed apical expression of AQP5 in many acinar cells, strong expression in intercalated ducts (ICDs) of the normal submandibular gland at Day 14, and strong expression in duct-like structures (DLSs) during regeneration from Day 0 to 7. Read More

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http://dx.doi.org/10.2334/josnusd.17-0491DOI Listing
January 2018
1 Read

Effects of α-tocopherol on bone marrow mesenchymal cells derived from type II diabetes mellitus rats.

J Oral Sci 2018 ;60(4):579-587

Department of Periodontology, Osaka Dental University.

It is widely accepted that vitamin E (VE) acts as an antioxidant and is involved in various metabolic systems including the regulation of gene expression and inhibition of cell proliferation. The most predominant isoform of VE in the living body is α-tocopherol. However, the influence of α-tocopherol on bone marrow mesenchymal cells (BMMCs) in a background of type II diabetes mellitus (DM) has not been investigated. Read More

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http://dx.doi.org/10.2334/josnusd.17-0422DOI Listing
January 2018
1 Read

Ultraviolet treatment restores bioactivity of titanium mesh plate degraded by contact with medical gloves.

J Oral Sci 2018 ;60(4):567-573

Division of Advanced Prosthodontics, Weintraub Center for Reconstructive Biotechnology, UCLA School of Dentistry.

Titanium mesh plate (Ti mesh) used for bone augmentation inadvertently comes into contact with medical gloves during trimming and bending. We tested the hypotheses that glove contact degrades the biological capability of Ti mesh and that ultraviolet treatment (UV) can restore this capability. Three groups of Ti mesh specimens were prepared: as-received (AR), after glove contact (GC), and after glove contact followed by UV treatment. Read More

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http://dx.doi.org/10.2334/josnusd.17-0443DOI Listing
January 2018
1 Read

Effect of hypoxia on the expression of CCAAT/enhancer-binding protein β and receptor activator of nuclear factor kappa-B ligand in periodontal ligament cells.

J Oral Sci 2018 ;60(4):544-551

Department of Pediatric Dentistry, Nihon University School of Dentistry.

Hypoxia after traumatic injuries to a tooth is one of the causes of subsequent root resorption. Inflammatory cytokines produced under hypoxic conditions are associated with root resorption, but the mechanism has not been fully understood. In this study, the role of hypoxia-inducible factor-1 (HIF-1) signaling in the regulation of CCAAT (cytosine-cytosine-adenosine-adenosine-thymidine)/enhancer-binding protein-β (C/EBPβ) and the receptor activator of nuclear factor kappa-B ligand (RANKL) expressions in immortalized human periodontal ligament (PDL) cells was investigated. Read More

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http://dx.doi.org/10.2334/josnusd.17-0436DOI Listing
January 2018
2 Reads

Transplantation effects of dental pulp-derived cells on peripheral nerve regeneration in crushed sciatic nerve injury.

J Oral Sci 2018 ;60(4):526-535

Department of Oral Anatomy, Aichi-Gakuin University School of Dentistry.

The effects of transplanted human dental pulp-derived cells (DPCs) on peripheral nerve regeneration were studied in a rat model of sciatic nerve crush injury. In one group, DPCs were transplanted into the compression site (cell transplantation group); the control group underwent no transplantation (crushed group). Sciatic nerve regeneration was determined based on the recovery of motor function and histological and immunohistochemical analyses. Read More

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http://dx.doi.org/10.2334/josnusd.17-0462DOI Listing
January 2018
2 Reads

Hypoxia-induced upregulation of angiogenic factors in immortalized human periodontal ligament fibroblasts.

J Oral Sci 2018 ;60(4):519-525

Department of Pediatric Dentistry, Nihon University School of Dentistry.

Hypoxia induces complex cellular responses that are mediated by a key transcription factor, hypoxia-inducible factor-1 (HIF-1). HIF-1 promotes production of cytokines and angiogenic factors and contributes to recovery of injured tissues. In the present study, expressions of angiogenin (ANG) and vascular endothelial growth factor (VEGF), which are potent angiogenic factors in mammalian tissues, were examined in immortalized fibroblasts exposed to hypoxia. Read More

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http://dx.doi.org/10.2334/josnusd.17-0441DOI Listing
January 2018
1 Read

Medullary neural circuit regeneration after trigeminal nerve transection.

J Oral Sci 2018 ;60(4):500-506

Department of Physiology, Nihon University School of Dentistry.

The inferior alveolar nerve (IAN) comprises several types of sensory fibers. To clarify whether each type of primary afferent is regenerated comparably after injury, we developed a model of complete IAN transection (IANX) in mice. A retrograde tracer, fluoro-gold, injected into the mental skin was transferred to the cell bodies of a subset of isolectin B4 (IB4)-binding (non-peptidergic C) or CGRP-positive (peptidergic C) neurons at 2 weeks post-axotomy, indicating that the injured C afferents had regenerated anatomically. Read More

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http://dx.doi.org/10.2334/josnusd.17-0457DOI Listing
January 2018
2 Reads

Connexin 43 expression in satellite glial cells contributes to ectopic tooth-pulp pain.

J Oral Sci 2018 ;60(4):493-499

Department of Physiology, Nihon University School of Dentistry.

Pulpitis often causes referred pain in opposing teeth. However, the precise mechanism underlying ectopic pain associated with tooth-pulp inflammation remains unclear. We performed the present study to test the hypothesis that functional interactions between satellite glial cells (SGCs) and trigeminal ganglion (TG) neurons are involved in ectopic orofacial pain associated with tooth-pulp inflammation. Read More

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http://dx.doi.org/10.2334/josnusd.17-0452DOI Listing
January 2018
1 Read

Long-term clinical and radiographic evaluation of the effectiveness of direct pulp-capping materials.

J Oral Sci 2018 Dec 20. Epub 2018 Dec 20.

Department of Periodontology and Endodontology, Nagasaki University Graduate School of Biomedical Sciences.

The aim of this review was to assess the effectiveness of different direct pulp-capping (DPC) materials for human pulp-exposed teeth. An electronic search was performed on 20 February 2018. Long-term clinical and radiographic evaluations of the effectiveness of different DPC materials for use on human pulp-exposed teeth were included. Read More

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https://www.jstage.jst.go.jp/article/josnusd/advpub/0/advpub
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http://dx.doi.org/10.2334/josnusd.18-0125DOI Listing
December 2018
3 Reads

Change in muscle hardness after trigger point injection and physiotherapy for myofascial pain syndrome.

J Oral Sci 2018 Dec 20. Epub 2018 Dec 20.

Department of Oral Diagnostic Sciences, Nihon University School of Dentistry.

Assessment and treatment of masticatory myofascial pain syndrome (MPS) are not standardized and remain controversial. We examined whether muscle hardness was useful for evaluating masticatory MPS and analyzed the effectiveness of treatments such as stretching and massage (SM) and trigger point injection (TPI). Twenty healthy volunteers and 20 MPS patients were enrolled. Read More

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http://dx.doi.org/10.2334/josnusd.17-0453DOI Listing
December 2018
3 Reads

The effect of mesenchymal stem cells on osteoclast precursor cell differentiation.

J Oral Sci 2018 Dec 11. Epub 2018 Dec 11.

Department of Orthodontics, Division of Oral Health and Development, Hiroshima University Hospital.

Transplantation of mesenchymal stem cells (MSCs) has been extensively studied in the field of regenerative medicine. Bone regeneration is achieved via the interaction of osteoblasts and osteoclasts. However, the influence of MSCs on osteoclasts is unknown. Read More

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http://dx.doi.org/10.2334/josnusd.17-0315DOI Listing
December 2018
1 Read

Effects of xylitol-containing chewing gum on the oral microbiota.

J Oral Sci 2018 Dec 15;60(4):588-594. Epub 2018 Nov 15.

Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University.

In this interventional study, a randomized controlled trial was used to evaluate the short-term effects of xylitol-containing chewing gum on the salivary microbiota. In total, 70 healthy adult men recruited from the Japan Ground Self Defense Force participated in the study during a 2-day training at Yamaguchi camp, Yamaguchi Prefecture, Japan. The men were randomly divided into two groups: one group chewed two pieces of xylitol-containing chewing gum 7 times/day for 2 days (n = 34) and the other did not (n = 36). Read More

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https://www.jstage.jst.go.jp/article/josnusd/advpub/0/advpub
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http://dx.doi.org/10.2334/josnusd.17-0446DOI Listing
December 2018
11 Reads

Expression of the Forkhead box transcription factor Foxo3a in human periapical granulomas.

J Oral Sci 2018 Dec 15;60(4):479-483. Epub 2018 Nov 15.

Department of Endodontics, Nihon University School of Dentistry.

It has been reported that Forkhead box transcription factor class O3a (Foxo3a) is expressed in rheumatoid arthritis, a chronic inflammatory condition accompanied by bone resorption, and plays a role in its pathology. However, it has remained unclear whether Foxo3a is involved in the pathogenesis of periapical granulomas. The present study was performed to compare the expression of Foxo3a in periapical granulomas and healthy gingival tissues. Read More

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http://dx.doi.org/10.2334/josnusd.17-0439DOI Listing
December 2018
3 Reads

Differential dendritic cell responses to cell wall mannan of Candida albicans, Candida parapsilosis, and Candida dubliniensis.

J Oral Sci 2018 Dec 15;60(4):557-566. Epub 2018 Nov 15.

Research Unit on Oral Microbiology and Immunology and Department of Microbiology, Faculty of Dentistry, Chulalongkorn University.

Mannan (mannosylated glycoproteins) in the outermost layer of the Candida cell wall may be the first molecules that interact with host dendritic cells (DCs) and activate immune responses that determine disease outcomes. However, little is known about how different mannan structures of common oral Candida species affect DC activation. The effects of heat-inactivated (HI) yeast cells and soluble mannan of Candida albicans, Candida parapsilosis, and Candida dubliniensis on bone marrow-derived DC (BMDC) responses were compared. Read More

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https://www.jstage.jst.go.jp/article/josnusd/advpub/0/advpub
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http://dx.doi.org/10.2334/josnusd.17-0426DOI Listing
December 2018
20 Reads

Retrospective clinical study of 296 patients with mass lesions of the tongue.

J Oral Sci 2018 Dec 15;60(4):574-578. Epub 2018 Nov 15.

Department of Oral and Maxillofacial Surgery, Nihon University School of Dentistry.

To better understand the clinical features of mass lesions of the tongue, we retrospectively evaluated frequency, recurrence rate, and complications in 296 patients who had undergone surgery for such lesions. The diagnoses were fibroma (43.6%), mucous cyst (14. Read More

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https://www.jstage.jst.go.jp/article/josnusd/advpub/0/advpub
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http://dx.doi.org/10.2334/josnusd.17-0317DOI Listing
December 2018
13 Reads

Trends in domiciliary dental care including the need for oral appliances and dental technicians in Japan.

J Oral Sci 2018 Dec 26;60(4):626-633. Epub 2018 Oct 26.

Department of Oral Prosthetic Engineering, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University.

The need for domiciliary dental care (DDC) for people requiring long-term nursing care is increasing as the super-aged society of Japan grows still older. Dysphagia diagnosis and rehabilitation are becoming more important in DDC; thus, the need for prostheses used for dysphasia rehabilitation is presumed to be increasing. To identify DDC trends in Japan, as well as the need for prostheses and dental technicians for DDC, we sent a self-administered questionnaire to dentists providing DDC and analyzed responses from 138 dentists (valid response rate, 39. Read More

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http://dx.doi.org/10.2334/josnusd.18-0053DOI Listing
December 2018
12 Reads

Comparison of the bone augmentation ability of absorbable collagen sponge with that of hydroxyapatite/collagen composite.

J Oral Sci 2018 Dec 26;60(4):514-518. Epub 2018 Oct 26.

Department of Periodontology, Nihon University School of Dentistry.

The present study was designed to compare the bone augmentation ability of absorbable collagen sponge (ACS) with that of hydroxyapatite/collagen composite (HAP/Col) using a rat calvaria defect model. Bone defects were created artificially on the surface of the calvariae of 10-week-old male Fisher rats, and then cylindral plastic caps filled with ACS or HAP/Col were placed on the defects. This area was designated as the region of interest (ROI) and new bone formation was observed at 0, 4, 8, and 12 weeks after surgery using micro-CT. Read More

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http://dx.doi.org/10.2334/josnusd.17-0465DOI Listing
December 2018
7 Reads

Risk factors for failure of orthodontic mini-screws placed in the median palate.

J Oral Sci 2018 Oct 26. Epub 2018 Oct 26.

Department of Orthodontics, Nihon University School of Dentistry.

This study investigated the stability of mini-screws placed in the median palate. The study included 25 patients (7 males, 18 females; mean age, 23.4 ± 5. Read More

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http://dx.doi.org/10.2334/josnusd.17-0377DOI Listing
October 2018
11 Reads

Effect of age on pulpal blood flow in human teeth during orthodontic movement.

J Oral Sci 2018 ;60(3):446-452

Department of Orthodontics, Gulhane Dentistry Faculty, Health Sciences University.

We aimed to assess the relationship between age, pulpal blood flow (PBF), and orthodontic treatment outcomes. Decreased blood supply to pulp cells commonly occurs with age and can change the response of pulp to orthodontic tooth movement. This study was conducted in 28 human subjects divided into 2 groups according to age. Read More

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http://dx.doi.org/10.2334/josnusd.17-0316DOI Listing
February 2019
2 Reads

A large-scale study of treatment methods for foreign bodies in the maxillary sinus.

J Oral Sci 2018 ;60(3):321-328

Department of Oral and Maxillofacial Surgery, Nihon University School of Dentistry.

Recently, reports regarding a foreign body in the maxillary sinus have considerably increased, with the majority being iatrogenic cases resulting from dental treatment. This study involves an extensive review of the Japanese literature, including 112 papers from 1978 to 2017. These papers documented total 407 cases of a foreign body in the maxillary sinus. Read More

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https://www.jstage.jst.go.jp/article/josnusd/60/3/60_18-0109
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http://dx.doi.org/10.2334/josnusd.18-0109DOI Listing
February 2019
14 Reads

Occlusion accuracy of restorations and removable partial dentures fabricated using the impression under occlusal force with functionally generated path recording.

J Oral Sci 2018 Dec 30;60(4):484-492. Epub 2018 Aug 30.

Department of Removable Prosthodontics, Tsurumi University School of Dental Medicine.

To evaluate the occlusion accuracy of a novel impression technique, excessively high occlusion and the occlusal contact area during lateral movements were compared between metal restorations (restorations) and removable partial dentures (RPDs) fabricated using conventional and novel techniques. Both restorations and RPDs were fabricated on the simulation model with the precise displacement of the remaining teeth and soft tissue. For the novel technique, functionally generated path (FGP) recording and impression under occlusal force were simultaneously performed using a custom tray with an FGP table. Read More

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http://dx.doi.org/10.2334/josnusd.17-0461DOI Listing
December 2018
2 Reads

IL-1β and TNF-α regulate mouse amelotin gene transcription in gingival epithelial cells.

J Oral Sci 2018 Sep 30;60(3):388-398. Epub 2018 Aug 30.

Department of Periodontology, Nihon University School of Dentistry at Matsudo.

Amelotin (AMTN) is an enamel protein expressed in maturation-stage ameloblasts and junctional epithelium. To clarify the transcriptional regulation of the AMTN gene by interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α), we conducted real-time PCR, Western blotting, transient transfection analyses with luciferase constructs including various lengths of the mouse AMTN gene promoter, and gel shift and chromatin immunoprecipitation assays using mouse gingival epithelial GE1 cells. The levels of AMTN mRNA and protein in GE1 cells were increased after 6 h of stimulation with IL-1β (1 ng/mL) and TNF-α (10 ng/mL). Read More

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http://dx.doi.org/10.2334/josnusd.17-0388DOI Listing
September 2018
5 Reads

New oral hygiene care regimen reduces postoperative oral bacteria count and number of days with elevated fever in ICU patients with esophageal cancer.

J Oral Sci 2018 Dec 30;60(4):536-543. Epub 2018 Aug 30.

Department of Preventive Dentistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.

Using a controlled pre/post study design, we investigated the effects of professional mechanical cleaning of the oral cavity with benzethonium chloride, interdental brushes, and hydrogen peroxide on the number of oral bacteria and postoperative complications among esophageal cancer patients in an intensive care unit. Before surgery, 44 patients with esophageal cancer were recruited at Okayama Hospital from January through August 2015. The control group (n = 23) received routine oral hygiene care in the intensive care unit. Read More

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http://dx.doi.org/10.2334/josnusd.17-0381DOI Listing
December 2018
1 Read

Phenotypic alteration of basal cells in oral lichen planus; switching keratin 19 and desmoglein 1 expression.

J Oral Sci 2018 Dec 25;60(4):507-513. Epub 2018 Aug 25.

Department of Oral Pathology, Matsumoto Dental University.

In oral lichen planus, extracellular matrix and basal cells are damaged by T-lymphocytes. As a consequence, changes in expression of collagen fibers within the connective tissue and cytoskeletons of the epithelial tissue can be observed. With the goal of examining the characteristic changes undergone by basal cells as a consequence of T-lymphocytes damage in oral lichen planus, we investigated protein expression in the epithelial-connective junction. Read More

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http://dx.doi.org/10.2334/josnusd.17-0396DOI Listing
December 2018
2 Reads

Effect of a silane and phosphate functional monomer on shear bond strength of a resin-based luting agent to lithium disilicate ceramic and quartz materials.

J Oral Sci 2018 Sep 25;60(3):360-366. Epub 2018 Aug 25.

Department of Fixed Prosthodontics, Nihon University School of Dentistry.

This study examined the effect of silane and phosphate functional monomer on bond strengths between a resin-based luting agent joined to a lithium disilicate ceramic (IPS e.max) and silica (quartz) materials. The e. Read More

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http://dx.doi.org/10.2334/josnusd.17-0383DOI Listing
September 2018
2 Reads

A static magnetic field inhibits the expression of platelet-derived growth factor-AA in human oral squamous cell carcinoma.

J Oral Sci 2018 Sep 25;60(3):374-380. Epub 2018 Aug 25.

Department of Partial Denture Prosthodontics, Nihon University School of Dentistry.

Magnetic attachments are commonly used for overdentures. The deleterious effects of exposure to magnetic flux on human health have not been substantiated so far; nevertheless, there is a need to understand the extent of magnetic field exposure in the oral area resulting from the use of magnetic attachments. The purpose of this study was to investigate the influence of a magnetic field on oral squamous cell carcinoma. Read More

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https://www.jstage.jst.go.jp/article/josnusd/60/3/60_17-0380
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http://dx.doi.org/10.2334/josnusd.17-0380DOI Listing
September 2018
15 Reads

Utility of the luminance standard deviation to quantify magnetic resonance imaging motion artifact induced by tongue movement.

J Oral Sci 2018 Sep 25;60(3):399-404. Epub 2018 Aug 25.

Department of Removable Prosthodontics, Nihon University School of Dentistry at Matsudo.

Clear magnetic resonance imaging (MRI) is required to diagnose tongue cancer. However, the absence of occlusal support may cause tongue movements which are known to introduce artifacts on the MR image. This pilot study compared the manifest of artifacts from the tongue at rest and during motion using luminance standard deviation (LSD) to quantify the artifacts, in dentulous subjects. Read More

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http://dx.doi.org/10.2334/josnusd.17-0322DOI Listing
September 2018
2 Reads

Nanofilled and conventional resin-modified glass ionomer fillings combined with connective tissue grafts for treatment of gingival recessions with non-carious cervical lesions.

J Oral Sci 2018 Sep 25;60(3):344-351. Epub 2018 Aug 25.

Department of Periodontology, Faculty of Dentistry, Hacettepe University.

The aim of this study was to evaluate the clinical root coverage results of subepithelial connective tissue grafts (SCTG) performed on teeth with gingival recessions and non-carious cervical lesions (NCCLs) that were restored with cervical fillings and compare the results of two different filling materials: resin-modified glass ionomer (RMGIC) and nano-ionomer cements (NIC). A total of 54 teeth with Miller Class I gingival recessions with or without NCCLs in 36 patients (28 females, 8 males) were treated with SCTGs. Cervical lesions were randomly treated with RMGIC or NIC restorations. Read More

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http://dx.doi.org/10.2334/josnusd.17-0190DOI Listing
September 2018
4 Reads

Micro-CT observation of in vivo temporal change in mandibular condyle morphology in BMAL1 knockout mice.

J Oral Sci 2018 Dec 25;60(4):473-478. Epub 2018 Aug 25.

Department of Oral and Maxillofacial Radiology, Nihon University School of Dentistry.

Brain and muscle Arnt-like protein-1 (BMAL1) knockout mice exhibit accelerated aging, abnormal glucose metabolism, and impaired adipocyte differentiation, among other phenotypes, which are effects associated with the BMAL1 gene. No study has investigated temporal changes in the deformation of the mandibular condyle and the presence of calcification in areas surrounding the mandibular condyle. In a study of 12 C57/BL strain mice under inhalation anesthesia, we collected images of the mandibular condyle at 6 weeks after birth and then every 5 weeks from 10 to 25 weeks after birth. Read More

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https://www.jstage.jst.go.jp/article/josnusd/advpub/0/advpub
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http://dx.doi.org/10.2334/josnusd.17-0390DOI Listing
December 2018
20 Reads

Expression of silent information regulator 2 homolog 1 (SIRT1) in periapical granulomas.

J Oral Sci 2018 Sep 12;60(3):411-417. Epub 2018 Aug 12.

Department of Endodontics, Nihon University School of Dentistry.

Silent information regulator 2 homolog 1 (SIRT1) inhibits oxidative injury and has anti-inflammatory effects. SIRT1 may be involved in healing of periapical periodontitis; however, SIRT1 expression in periapical periodontitis lesions has not been investigated. This study evaluated SIRT1 expression and a marker of oxidative stress-8-hydroxy-2'-deoxyguanosine (8-OHdG)-in periapical granulomas. Read More

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http://dx.doi.org/10.2334/josnusd.17-0412DOI Listing
September 2018
14 Reads

Influences of mechanical barrier permeability on guided bone augmentation in the rat calvarium.

J Oral Sci 2018 Sep 12;60(3):453-459. Epub 2018 Aug 12.

Department of Periodontology, Nihon University School of Dentistry.

We used radiological and histological analyses to evaluate the effects of mechanical barrier permeability in a rat model of calvarial guided bone augmentation (GBA). The calvaria of 20 rats were exposed, and one of four types of plastic caps (an occlusive cylindrical plastic cap; a plastic cap with no top; a plastic cap with three holes; and a plastic cap with four holes) was randomly placed on both sides. Newly generated bone in the plastic caps was evaluated with micro-computed tomography (micro-CT) and histological analysis. Read More

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https://www.jstage.jst.go.jp/article/josnusd/60/3/60_17-0362
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http://dx.doi.org/10.2334/josnusd.17-0362DOI Listing
September 2018
6 Reads

Cellular responses of periodontal ligament stem cells to a novel synthesized form of calcium hydrogen phosphate with a hydroxyapatite-like surface for periodontal tissue engineering.

J Oral Sci 2018 Sep 12;60(3):428-437. Epub 2018 Aug 12.

Department of Chemistry, Faculty of Science, Chulalongkorn University.

Calcium hydrogen phosphate with a hydroxyapatite-like surface (CHP-HA) is a novel synthesized compound designed to overcome the limitations of bioactive ceramics. It was originally applied as nano-sized HA strips covering core plates to enhance the degree of interfacial attachment. The objective of the present study was to examine the cellular attachment, proliferation, and osteogenic differentiation of periodontal ligament stem cells (PDLSCs) on a CHP-HA substrate in comparison with conventional nanohydroxyapatite (NanoHA). Read More

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http://dx.doi.org/10.2334/josnusd.17-0343DOI Listing
September 2018
1 Read

Salivary nitrate-nitrite conversion capacity after nitrate ingestion and incidence of Veillonella spp. in elderly individuals.

J Oral Sci 2018 Sep 12;60(3):405-410. Epub 2018 Aug 12.

The Iwate Research Center for Wildlife Diseases.

Dietary nitrate has several beneficial effects, including blood pressure reduction and improved oxygen consumption efficiency, but in order to do so it must first be reduced to nitrite by oral bacteria. Veillonella spp., a strictly anaerobic group, are the most prevalent nitrate-reducing bacteria in the oral cavity. Read More

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http://dx.doi.org/10.2334/josnusd.17-0337DOI Listing
September 2018
2 Reads

Leachables and cytotoxicity of root canal sealers.

J Oral Sci 2018 Sep 12;60(3):381-387. Epub 2018 Aug 12.

Department of Dental and Oral Pathology, Lithuanian University of Health Sciences.

This in vitro study aimed to detect leaching components from an epoxy resin- and a methacrylate-based endodontic sealer and correlate them to cytotoxicity induced by material extracts for up to 36 weeks. We qualitatively determined the substances released by aged AH Plus and RealSeal SE specimens at seven intervals between 0 and 36 weeks. Quantification was performed by ultra-performance liquid chromatography/mass spectrometry (UPLC/MS). Read More

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http://dx.doi.org/10.2334/josnusd.17-0173DOI Listing
September 2018
2 Reads

Periodontal status of buccally and palatally impacted maxillary canines after surgical-orthodontic treatment with open technique.

J Oral Sci 2018 Dec 9;60(4):552-556. Epub 2018 Jul 9.

Department of Life Health and Environmental Sciences, University of L'Aquila.

This study investigated differences in periodontal health variables between buccally impacted maxillary canines (BIMC) and palatally impacted maxillary canines (PIMC) after surgical-orthodontic treatment with open technique. Nineteen patients were enrolled: 10 with unilateral BIMC (5 men, 5 women; mean age 18.50 ± 1. Read More

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http://dx.doi.org/10.2334/josnusd.17-0394DOI Listing
December 2018
18 Reads

Conditioned medium from rat dental pulp reduces the number of osteoclasts via attenuation of adhesiveness in osteoclast precursors.

J Oral Sci 2018 Sep 9;60(3):352-359. Epub 2018 Jul 9.

Department of Pharmacology, School of Dentistry, Aichi Gakuin University.

Dental pulp is known to play crucial roles in homeostasis of teeth and periodontal tissue. Although resorption of bone around the roots of nonvital teeth is occasionally observed in clinical practice, little is known about the role of dental pulp in osteoclastogenesis. Here we evaluated the effects of conditioned medium (CM) from rat dental pulp on osteoclastogenesis. Read More

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http://dx.doi.org/10.2334/josnusd.17-0342DOI Listing
September 2018
3 Reads

Effect of a coating material containing surface reaction-type pre-reacted glass-ionomer filler on prevention of primary enamel demineralization detected by optical coherence tomography.

J Oral Sci 2018 Sep 9;60(3):367-373. Epub 2018 Jul 9.

Department of Operative Dentistry, Nihon University School of Dentistry.

We used optical coherence tomography to examine the effect of a coating material containing surface reaction-type pre-reacted glass-ionomer (S-PRG) filler on primary enamel demineralization in 18 extracted human primary teeth. The pulp was removed, and each tooth was ultrasonically cleaned with distilled water. Six teeth were treated with 0. Read More

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http://dx.doi.org/10.2334/josnusd.17-0256DOI Listing
September 2018
2 Reads