1,012 results match your criteria Journal of nuclear medicine technology[Journal]


PHARMACOLOGY PART 5: CT AND MRI CONTRAST.

J Nucl Med Technol 2019 Feb 15. Epub 2019 Feb 15.

Charles Sturt University, Australia.

Pharmacology principles provide key understanding that underpins the clinical and research roles of nuclear medicine practitioners. The scope of practice of the nuclear medicine technologist demands knowledge and understanding of indications, contraindications, warnings, precautions, proper use, drug interactions, and adverse reactions for each medication to be used. This article is the sixth in a series of articles that aims to enhance the understanding of pharmacological principles relevant to nuclear medicine. Read More

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http://dx.doi.org/10.2967/jnmt.118.220012DOI Listing
February 2019

PHARMACOLOGY PART 4: NUCLEAR CARDIOLOGY.

J Nucl Med Technol 2019 Feb 15. Epub 2019 Feb 15.

Charles Sturt University, Australia.

Pharmacology principles provide key understanding that underpins the clinical and research roles of nuclear medicine practitioners in nuclear cardiology. The scope of practice of the nuclear medicine technologist demands knowledge and understanding of indications, contraindications, warnings, precautions, proper use, drug interactions, and adverse reactions for each medication to be used. This article is the fifth in a series of articles that aims to enhance the understanding of pharmacological principles relevant to nuclear medicine. Read More

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http://dx.doi.org/10.2967/jnmt.118.219675DOI Listing
February 2019

Coexisting sources of false positive reflux on a direct radionuclide cystography scan.

J Nucl Med Technol 2019 Feb 15. Epub 2019 Feb 15.

Department of Nuclear Medicine, Taleghani Educational Hospital, School of Medicine, Shahid Beheshti, Iran, Islamic Republic of.

Direct radionuclide cystography (DRC) is currently a popular method for evaluation of vesicoureteral reflux (VUR), in spite of its pitfalls and drawbacks in producing false positive results. In this article, it is intended to present a case with two sources of false positive reflux on a DRC scan. Read More

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http://dx.doi.org/10.2967/jnmt.118.222075DOI Listing
February 2019
1 Read

Fast PET preview image reconstruction, streaming, and visualization during data acquisition: a preliminary study.

J Nucl Med Technol 2019 Feb 15. Epub 2019 Feb 15.

Philips, United States.

Background and Positron emission tomography (PET) acquisition and reconstruction is time consuming. A PET preview image is commonly reconstructed at the end of data acquisition of each bed frame in the step and shoot mode. We propose a scheme to reconstruct, stream, and visualize the PET preview image during acquisition to provide a quasi real-time visual feedback. Read More

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http://dx.doi.org/10.2967/jnmt.118.218511DOI Listing
February 2019

Abnormal Biodistribution of Tc99m Red Blood Cell Labeled Multi-Gated Acquisition Scan in the Presence of Suspected Cold Agglutinin Disease.

J Nucl Med Technol 2019 Jan 29. Epub 2019 Jan 29.

Walter Reed National Military Medical Center, United States.

Tc-red blood cells (RBCs) labeled multi-gated acquisition (MUGA) scan is a procedure in which the patient's red blood cells (RBCs) are radiolabeled and electrocardiograph (ECG)-gated cardiac scintigraphy is obtained to assess the heart's pumping efficiency. Cold agglutinin disease (CAD), or cold antibody autoimmune hemolytic anemia, is a rare form of autoimmune hemolytic anemia in which the body's immune system attacks and destroys its own red blood cells. This case addresses an altered biodistribution pattern of radiolabeled RBCs in the presence of suspected cold agglutinin disease observed during a MUGA scan. Read More

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http://dx.doi.org/10.2967/jnmt.118.222182DOI Listing
January 2019
2 Reads

Using professional development opportunities to advance your nuclear medicine career.

Authors:
Jared D Seliger

J Nucl Med Technol 2019 Jan 29. Epub 2019 Jan 29.

Allen College, United States.

Nuclear medicine technologists (NMT) have multiple opportunities to advance their careers beyond an entry-level technologist. Many careers that NMTs can obtain require additional skills, education or qualifications. Participating in professional development (PD) opportunities is necessary to acquire the skills necessary for career advancement. Read More

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http://tech.snmjournals.org/lookup/doi/10.2967/jnmt.118.2103
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http://dx.doi.org/10.2967/jnmt.118.210351DOI Listing
January 2019
2 Reads

Left Ventricular Assist Device Associated Gastrointestinal Bleeding: Recognition of an Iatrogenic Etiology on Technetium-99m Tagged Red Blood Cell Scintigraphy.

J Nucl Med Technol 2019 Jan 29. Epub 2019 Jan 29.

Mayo Clinic in Arizona, United States.

Technetium-99m (Tc) tagged RBC scintigraphy is the imaging modality of choice in the diagnosis of active gastrointestinal bleeding (GIB). Continuous-flow left ventricular assist devices (CF-LVADs) are the state-of-the-art treatment for advanced heart failure, with GIB as the most common complication. Recognition of the distinctive imaging feature of CF-LVADs on scintigraphic images could aid diagnosis of GIB. Read More

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http://dx.doi.org/10.2967/jnmt.118.220061DOI Listing
January 2019
1 Read

Utility of Scintigraphy in Assessment of Non-infectious Complications of Peritoneal Dialysis.

J Nucl Med Technol 2019 Jan 29. Epub 2019 Jan 29.

University of Alabama at Birmingham, United States.

Dialysis is an artificial process to remove waste products and excess water from the body in patients with kidney failure. There are two main types of dialysis available, hemodialysis (HD) which uses an artificial filtration apparatus and is done usually at specialized centers but can be done in a patient's home and peritoneal dialysis (PD). Peritoneal dialysis functions by placing dialysis fluid also called dialysate into the peritoneal cavity allowing for solute to be removed from the peritoneal capillaries through diffusion across a chemical gradient into the dialysate and removal of water through an osmotic gradient created by hypertonic dextrose. Read More

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http://dx.doi.org/10.2967/jnmt.118.223156DOI Listing
January 2019
1 Read

Urinary Voiding as a Tool to Reduce Radiation Exposure in the Nuclear Stress Lab.

J Nucl Med Technol 2019 Jan 25. Epub 2019 Jan 25.

Mayo Clinic Arizona, United States.

Nuclear stress testing is being increasingly utilized in the cardiovascular risk stratification of patients. Radiation is an important consideration and attempts to minimize exposure should be implemented. Efficiency and cost effectiveness are cornerstones in the delivery of quality patient care and should also be considered when implementing change. Read More

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http://dx.doi.org/10.2967/jnmt.118.212548DOI Listing
January 2019
2 Reads

Brain Quality Assurance - How to Acquire the Best Brain Images Possible.

J Nucl Med Technol 2019 Jan 25. Epub 2019 Jan 25.

., United States.

Many factors can affect image quality regardless of what organ a Nuclear Medicine Technologist (NMT) is imaging. It is extremely important that every aspect of an image protocol be followed properly to ensure the highest image quality. If image protocols are not followed properly, image quality as well as a nuclear medicine physician's interpretation and final report, and conceivably a patient's care plan and management by their physician, could be negatively affected. Read More

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http://dx.doi.org/10.2967/jnmt.118.211771DOI Listing
January 2019

DaTQUANT: The Future of Diagnosing Parkinson's Disease.

J Nucl Med Technol 2019 Jan 25. Epub 2019 Jan 25.

GateWay Community College, United States.

Idiopathic Parkinson's disease (PD) is a progressive neurological condition which affects the dopamine transporters in the substantia nigra of the brain. Currently, over ten million people are living with this disease world-wide, with thousands of newly diagnosed and undiagnosed cases added every year. The disease is difficult to differentiate from other similar disorders, as symptoms widely vary and can mimic other conditions. Read More

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http://dx.doi.org/10.2967/jnmt.118.222349DOI Listing
January 2019
8 Reads

Split-Dose FDG PET/CT-guided Microwave Ablation for Liver Metastasis Recurrence with Immediate Treatment Assessment.

J Nucl Med Technol 2019 Jan 25. Epub 2019 Jan 25.

San Antonio Uniformed Services Health Education Consortium, United States.

A 48-year-old man with history of colon cancer presented with recurrent hepatic metastasis along a prior microwave ablation (MWA) bed. Split-bolus, intraprocedural FDG PET was performed to guide repeat MWA and immediately confirm complete treatment. PET-guided ablation is highly accurate for targeting and treating malignant hepatic lesions and feasible for non-specialized tertiary care hospitals without an onsite cyclotron. Read More

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http://dx.doi.org/10.2967/jnmt.118.217406DOI Listing
January 2019

NMTCB Report.

Authors:
Katie Neal

J Nucl Med Technol 2018 Dec;46(4):9A

Executive Director.

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December 2018
1 Read

Brief Overview of the Fall 2018 SNMMI-TS Board Meeting.

Authors:
Norman E Bolus

J Nucl Med Technol 2018 Dec;46(4):8A

SNMMI-TS President.

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December 2018
1 Read

SNMMI Procedure Standard for Bone Scintigraphy 4.0.

J Nucl Med Technol 2018 Dec;46(4):398-404

Global Advanced Imaging, PLLC, Little Rock, Arkansas.

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December 2018
12 Reads

Erratum.

Authors:

J Nucl Med Technol 2018 Dec;46(4):383

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December 2018
1 Read

Amyloid Imaging.

Authors:
Jessica Williams

J Nucl Med Technol 2018 Dec;46(4):341-342

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http://tech.snmjournals.org/lookup/doi/10.2967/jnmt.118.2221
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http://dx.doi.org/10.2967/jnmt.118.222190DOI Listing
December 2018
1 Read

A Year in Review.

Authors:
Kathy S Thomas

J Nucl Med Technol 2018 Dec;46(4):319-320

Editor, JNMT.

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December 2018
1 Read

Biodistribution and Dosimetry of Indigenous I-Rituximab in B-Cell Lymphoma: Pilot Study estimating patient specific dose comparing two different dosimetric methods.

J Nucl Med Technol 2018 Nov 9. Epub 2018 Nov 9.

Radiation Medicine Centre, Bhabha Atomic Research Centre, Tata Memorial Centre Annexe, India.

Cost-containment through indigenous development and production and its subsequent examination in clinical settings would be a pivotal step for bringing radioimmunotherapy (RIT) agents to more widespread clinical practice in non-Hodgkin's lymphoma (NHL) patients, especially in developing countries. To examine the biodistribution and dosimetry of indigenously developed and radiolabeled I-Rituximab, using the monoclonal antibody of chimeric origin, in patients of B cell lymphoma for its potential use in RIT. This was a prospective study involving patients of B-cell NHL who underwent low dose diagnostic scan for the dosimetric and biodistribution studies. Read More

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http://tech.snmjournals.org/lookup/doi/10.2967/jnmt.118.2167
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http://dx.doi.org/10.2967/jnmt.118.216754DOI Listing
November 2018
21 Reads

Improving the spatial alignment in PET/CT using amplitude-based respiratory-gated PET and patient-specific breathing-instructed CT.

J Nucl Med Technol 2018 Nov 9. Epub 2018 Nov 9.

Department of Radiology and Nuclear Medicine, Radboud university medical center, Netherlands.

Appropriate attenuation correction is important for accurate quantification of standardized uptake values (SUVs) in positron emission tomography (PET). Patient respiratory motion can introduce a spatial mismatch between respiratory-gated PET and computed tomography (CT), reducing quantitative accuracy. In this study, the effect of a patient-specific breathing-instructed CT protocol on the spatial alignment between CT and amplitude-based optimal respiratory-gated PET images was investigated. Read More

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http://tech.snmjournals.org/lookup/doi/10.2967/jnmt.118.2159
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http://dx.doi.org/10.2967/jnmt.118.215970DOI Listing
November 2018
7 Reads

An Evaluation of Qualities of Nuclear Medicine Technology Programs and Graduates Leading to Employability.

J Nucl Med Technol 2018 Nov 9. Epub 2018 Nov 9.

Indiana University School of Medicine, United States.

To evaluate the association between qualities of nuclear medicine technology (NMT) programs and graduates, and employability. We identified all NMT certification board applicants who passed the entry level NMT exam between 2012 and 2017. Certificants were e-mailed a survey with questions regarding graduate qualities, program qualities, and initial employment. Read More

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http://tech.snmjournals.org/lookup/doi/10.2967/jnmt.118.2195
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http://dx.doi.org/10.2967/jnmt.118.219519DOI Listing
November 2018
9 Reads

Radiation Safety Certification: A Review.

Authors:
Cybil J Nielsen

J Nucl Med Technol 2018 Dec 9;46(4):321-325. Epub 2018 Nov 9.

Nuclear Medicine Technology Program, Department of Radiologic and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana

It has become common for nuclear medicine technologists to assume the responsibilities, or even the role, of the radiation safety officer or associate radiation safety officer. Their responsibilities are primarily related to the radioactive materials license but increasingly can include additional safety responsibilities within the hospital. These include CT, MRI, and fluoroscopy safety. Read More

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http://tech.snmjournals.org/lookup/doi/10.2967/jnmt.118.2095
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http://dx.doi.org/10.2967/jnmt.118.209528DOI Listing
December 2018
12 Reads

Comparison of Radioiodine uptake by Gamma Camera and Thyroid uptake probe-based methodologies and Diagnostic Radioiodine Scan in Differentiated thyroid carcinoma.

J Nucl Med Technol 2018 Nov 9. Epub 2018 Nov 9.

RADIATION MEDICINE CENTRE (BARC), Tata Memorial Hospital Annexe, India.

The objective of the study was to make a quantitative comparison of 72-hrs neck uptake calculated by gamma camera-based and thyroid uptake probe-based methods after administration of low-dose (111-148 MBq) of I capsule in thyroid carcinoma follow-up patients who have already been treated with I. The study group consists of 46 patients, of whom 14 were male (average 47.5 yrs) and 32 were female (average 38 yrs). Read More

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http://tech.snmjournals.org/lookup/doi/10.2967/jnmt.118.2078
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http://dx.doi.org/10.2967/jnmt.118.207837DOI Listing
November 2018
9 Reads

Technologist Approach to Global Dose Optimization.

J Nucl Med Technol 2018 Nov 9. Epub 2018 Nov 9.

Nuclear Medicine, University Hospitals Leuven, Belgium.

Nuclear Medicine Technologists (NMTs) are specialized health professionals that cover a wide range of tasks from clinical routine (including image acquisition and processing, radiopharmaceutical dispensing and administration, patient care and radioprotection tasks) to leading clinical research in the field of Nuclear Medicine. As a fundamental concern in all radiation sciences applied to medicine, protection of individuals against the harmful effects of ionizing radiation must be constantly revised and applied by the professionals involved in medical exposures. The acknowledgement that NMTs play a prominent role in patient management and a number of procedural steps both in diagnostic and therapeutic nuclear medicine applications, carries the duty to be trained and knowledgeable on the topic of radiation protection and dose optimization. Read More

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http://dx.doi.org/10.2967/jnmt.118.218131DOI Listing
November 2018
2 Reads

In patients we trust. Reliability of self-reported weight and size in patients attending a nuclear medicine department.

J Nucl Med Technol 2018 Nov 9. Epub 2018 Nov 9.

ZRN Rheinland, Germany.

The aim of the study was to assess the reliability of self-reported weight and size of nuclear medicine patients in view of recommendation for the weight-dependent tracer application for imaging and therapy. A total of 824 patients (334m, 490f) were asked to report their weight and size prior imaging or therapy and their level of confidence. Subsequently, weight and size of each patient was measured and body mass index (BMI), body surface area (BSA) and lean body mass (LBM) were calculated. Read More

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http://tech.snmjournals.org/lookup/doi/10.2967/jnmt.118.2163
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http://dx.doi.org/10.2967/jnmt.118.216317DOI Listing
November 2018
6 Reads

Integrative leadership and its use in providing excellent patient care while overcoming hospital challenges.

Authors:
Julie Bolin

J Nucl Med Technol 2018 Nov 9. Epub 2018 Nov 9.

Tucson Medical Center, United States.

Effective leadership in the healthcare setting is vital for delivering effective and efficient patient care while meeting organizational and departmental challenges. Hospitals face unique obstacles relating to regulation and accreditation, process inefficiencies, aging or difficult to treat patients, allocation of resources, and patient satisfaction. This article describes the characteristics of a leader, integrative leadership in the healthcare setting, and provides suggestions to engage coworkers in solving complex healthcare problems. Read More

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http://tech.snmjournals.org/lookup/doi/10.2967/jnmt.118.2192
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http://dx.doi.org/10.2967/jnmt.118.219212DOI Listing
November 2018
10 Reads

Accreditation and Assessment: The Basics for Nuclear Medicine Educators.

J Nucl Med Technol 2018 Nov 9. Epub 2018 Nov 9.

Pennsylvania College of Health Sciences, United States.

This article presents a high-level overview of accreditation and assessment in higher education.It is designed to provide nuclear medicine technology (NMT) educators with a foundational knowledge of accreditation and assessment. This foundation will help educators understand accreditation and assessment at the college/university and program levels by discussing key terminology and exploring the concept of a culture of assessment. Read More

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http://dx.doi.org/10.2967/jnmt.118.219113DOI Listing
November 2018
1 Read

Encouraging Lifelong Learning: An Educator's Perspective on Teaching and Learning for the Nuclear Medicine Technologist.

Authors:
Isabel T Breen

J Nucl Med Technol 2018 Nov 9. Epub 2018 Nov 9.

Rutgers University, United States.

The rapid influx of new technology and changing reimbursement and healthcare business models challenge nuclear medicine technology (NMT) educators to reexamine the effectiveness of traditional teaching methods. As a generation of technologists can attest, the skill sets and competencies taught today will not be the requirements of tomorrow. The question arises, "how can educators prepare students and the profession for future knowledge capacity?" The concept of lifelong learning (LLL) emerged in the 1970s as a response to the global paradigm shift from an industrial society to a knowledge society. Read More

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http://dx.doi.org/10.2967/jnmt.118.218545DOI Listing
November 2018

Assessing F-18 FDG uptake in the sentinel lymph node in breast cancer.

J Nucl Med Technol 2018 Nov 9. Epub 2018 Nov 9.

Trakya University Faculty of Medicine, Turkey.

Fluorine-18 fluorodeoxyglucose (F-FDG) positron emission tomography/computed tomography (PET/CT) has limited value in early breast cancer. Sentinel lymph node (SLN) biopsy is the current procedure of choice to search for small metastatic deposits in the axillary lymph nodes in early breast cancer. In this retrospective study, we re-evaluated F-FDG PET/CT images after locating SLN(s) on PET/CT with the help of SLN single photon emission computed tomography/computed tomography (SPECT/CT) images and assessed F-FDG uptake particularly in the SLN(s). Read More

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http://tech.snmjournals.org/lookup/doi/10.2967/jnmt.118.2197
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http://dx.doi.org/10.2967/jnmt.118.219758DOI Listing
November 2018
12 Reads

The influence of minimal misalignment on the repeatability of PET images examined by the repositioning of point sources.

J Nucl Med Technol 2018 Nov 9. Epub 2018 Nov 9.

Department of Health Sciences, Graduate School of Medical Sciences, Kyushu University, Japan.

We aimed to evaluate the influence of the minimal misalignment of the hot spot on the repeatability of PET images using the repositioning of point sources. Point sources with an inner-diameter of 1 mm were made with 1μL of F solution. Seven point sources were placed on the x-axis in the field-of-view. Read More

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http://tech.snmjournals.org/lookup/doi/10.2967/jnmt.118.2088
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http://dx.doi.org/10.2967/jnmt.118.208835DOI Listing
November 2018
8 Reads

IAC Grants First CT Accreditation to a Mobile Stroke Unit.

Authors:
Tamara A Sloper

J Nucl Med Technol 2018 Sep;46(3):9A-10A

Intersocietal Accreditation Commission.

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September 2018
4 Reads

Advancing the Profession with a Focus on Value and Quality.

Authors:
Norman E Bolus

J Nucl Med Technol 2018 Sep;46(3):7A-8A

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September 2018

Technologist News.

Authors:

J Nucl Med Technol 2018 Sep;46(3):12A-18A

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September 2018
1 Read

JRCNMT Report.

Authors:
Jan M Winn

J Nucl Med Technol 2018 Sep;46(3):11A

Executive Director, JRCNMT.

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September 2018
1 Read

The Model Practice Act for Nuclear Medicine Technology.

J Nucl Med Technol 2018 Sep;46(3):295

Cedars-Sinai Medical Center, Los Angeles, California.

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September 2018
1 Read

Erratum.

Authors:

J Nucl Med Technol 2018 Sep;46(3):294

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September 2018
1 Read

Building a Pool of Future Technologist Authors.

Authors:
Kathy S Thomas

J Nucl Med Technol 2018 Sep;46(3):219-220

Editor, JNMT.

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September 2018
4 Reads

Small Cell Transformation of Metastatic Prostate Adenocarcinoma Diagnosed by Dual Tracer PET/CT (Ga-PSMA and F-FDG): Potential Clinical Utility in Therapeutic Decision-Making and Treatment Monitoring.

J Nucl Med Technol 2018 Aug 23. Epub 2018 Aug 23.

RADIATION MEDICINE CENTRE (BARC), Tata Memorial Hospital Annexe, India.

Transformed small cell carcinoma of prostate represents a distinct tumor biology from the adenocarcinoma counterpart and penile metastasis from prostate cancer is a rare entity. Unique features of this transformation include unresponsiveness to hormonal therapy and presence of visceral metastases, which can demonstrate hypermetabolism on F-FDG PET/CT. The importance of dual tracer PET/CT using Ga-PSMA and F-FDG is illustrated in metastatic prostatic adenocarcinoma (Gleason's score 4+3=7) with previous history of bilateral orchidectomy, chemotherapy and radiotherapy, who presented with abdominal pain and backache, dysuria and increasing serum PSA. Read More

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http://dx.doi.org/10.2967/jnmt.118.215582DOI Listing
August 2018
4 Reads

Effects of Alzheimer Disease on Patients and Their Family.

J Nucl Med Technol 2018 Dec 23;46(4):335-340. Epub 2018 Aug 23.

Grabher Consulting and Specialty Services, Abingdon, Maryland, and Life Molecular Imaging, Inc., Boston, Massachusetts

The diagnosis of Alzheimer disease (AD) affects not only the patient but the entire family and their supporting caregivers. Understanding the stressors that affect these individuals enables us to provide the support and care they need to remain happy and healthy despite living with the diagnosis of AD. This continuing education article examines the epidemic of AD in the United States today and its emotional, psychologic, and financial effects. Read More

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http://dx.doi.org/10.2967/jnmt.118.218057DOI Listing
December 2018

Enhanced Gastric Emptying Scintigraphy to Assess Fundic Accommodation Using Intragastric Meal Distribution and Antral Contractility.

J Nucl Med Technol 2018 Aug 23. Epub 2018 Aug 23.

Temple University School of Medicine, United States.

Gastric emptying scintigraphy (GES) as now commonly performed measures only total gastric emptying. Intragastric meal distribution (IMD) immediately post meal ingestion (t= 0 min) (IMD0) ) can assess fundic accommodation (FA) and dynamic antral contraction scintigraphy (DACS) can assess antral motility.

Goals: 1) Incorporate IMD and DACS into GES; 2) Compare IMD0 using gastric division into anatomic proximal and distal halves vs more physiologic separation of the antrum from proximal stomach using DACS; 3) establish normal values. Read More

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http://dx.doi.org/10.2967/jnmt.118.215566DOI Listing
August 2018
1 Read

Comparison of the variability of SUVs normalized by skeletal volume with that of SUVs normalized by body weight in normal F-fluoride PET/CT studies.

J Nucl Med Technol 2018 Aug 23. Epub 2018 Aug 23.

Faculdade de Medicina da Universidade de São Paulo (FMUSP), Brazil.

to test the hypothesis that the variability of the standardized uptake values (SUVs) normalized by skeletal volume (SV) in F-fluoride PET/CT (F-NaF) studies is lower than that of the SUVs normalized by body weight (BW). the SUVs were obtained in whole skeletal volumes of interest (wsVOIs) in 163 selected F-NaF studies. These studies were performed for the investigation of bone metastases and considered normal by evaluation of PET and CT images. Read More

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http://dx.doi.org/10.2967/jnmt.118.215111DOI Listing

PHARMACOLOGY PART 3B: LESS COMMONLY USED INTERVENTIONAL MEDICATIONS AND ADJUNCTIVE MEDICATIONS IN GENERAL NUCLEAR MEDICINE.

J Nucl Med Technol 2018 Aug 23. Epub 2018 Aug 23.

Charles Sturt University, Australia.

The understanding of key principles in pharmacology is essential to the clinical and research nuclear medicine practitioner. The scope of practice of the nuclear medicine technologist requires capability around the indications, contraindications, warnings, precautions, proper use, drug interactions, and adverse reactions for interventional and adjunctive medications. This article is the companion article to the third in a series of articles that aims to enhance the understanding of pharmacological principles relevant to nuclear medicine. Read More

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http://dx.doi.org/10.2967/jnmt.118.215053DOI Listing
August 2018
10 Reads

Bilateral orbital soft tissue metastases from Renal Neuroendocrine Tumor: successful Theranostic application of Ga/Lu-DOTATATE with improvement of vision.

J Nucl Med Technol 2018 Aug 23. Epub 2018 Aug 23.

RADIATION MEDICINE CENTRE (BARC), Tata Memorial Hospital Annexe, Jerbai Wadia Road, Parel, Mumbai, India.

Gratifying clinical response obtained in the clinical setting of bilateral orbital metastases from renal neuroendocrine tumor (NET) is reported. A 53 year-old male, diagnosed case of renal NET (MIB1 index-4%), with symptoms of skeletal and abdominal pain, proptosis and decrease in vision of left eye, was found to harbor bilateral orbital soft tissue lesions on Ga-DOTATATE PET-CT and MRI in addition to widespread metastatic skeletal lesions, and metastatic lymph nodal disease. His symptoms worsened despite radiotherapy to left eye (20Gy) and long-acting octreotide therapy for 18 months, with increase in serum chromogranin A (CgA) level and was considered for Lutetium(Lu)-DOTATATE peptide receptor radionuclide therapy (PRRT). Read More

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http://dx.doi.org/10.2967/jnmt.118.217455DOI Listing
August 2018
2 Reads

SPECT-CT-guided ultrasound for parathyroid adenoma localisation - a one stop approach.

J Nucl Med Technol 2018 Aug 23. Epub 2018 Aug 23.

Royal Free London NHS Foundation Trust, United Kingdom.

To evaluate the accuracy of one-stop (single patient attendance) SPECT-CT-guided ultrasound (US) in the localisation of parathyroid adenomata (PTA). Secondary aims included analysing the effect of multiple PTA and concurrent thyroid disease on sensitivity. Patients with hyperparathyroidism that had undergone parathyroidectomy were identified over a 5 year period. Read More

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http://dx.doi.org/10.2967/jnmt.118.209767DOI Listing
August 2018
3 Reads

Practical Clinical Measurement of Radiotracer Concentration in Blood: Initial Device Concept and Feasibility Testing.

J Nucl Med Technol 2018 Dec 23;46(4):373-377. Epub 2018 Aug 23.

Lucerno Dynamics, Cary, North Carolina.

Kinetic analysis of PET data requires continuous measurement of radioactivity in the arterial blood throughout the acquisition time, termed the arterial input function. The arterial input function is used as an input to compartmental modeling, which can be a better predictor of disease progression than SUV measurements from static PET images. Current common methods of measuring blood concentrations include image-derived, population-based, and manual sampling. Read More

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http://dx.doi.org/10.2967/jnmt.118.212266DOI Listing
December 2018
2 Reads

Optimization of Parameters for Quantitative Analysis of I-ioflupane SPECT Images for Monitoring of Progression of Parkinson's Disease.

J Nucl Med Technol 2018 Aug 23. Epub 2018 Aug 23.

University of Arizona Health Sciences, Departments of Medical Imaging, Medicine and Biomedical, United States.

Quantitative assessment of dopamine transporter (DAT) imaging can aid in diagnosing Parkinson's disease (PD) and assessing disease progression in the context of therapeutic trials. Previously, the software program SBRquant was applied to I-ioflupane SPECT images acquired on healthy controls and subjects with PD. Earlier work on optimization of the parameters for differentiating between controls and subjects with dopaminergic deficits is extended here for maximizing change measurements associated with disease progression on longitudinally acquired scans. Read More

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http://dx.doi.org/10.2967/jnmt.118.213181DOI Listing
August 2018
20 Reads

Effects of web-based information on patient satisfaction and image quality in patients undergoing an F-FDG PET/CT examination - a randomised controlled trial.

J Nucl Med Technol 2018 Aug 3. Epub 2018 Aug 3.

Dept. of Immunology; Genetics and Pathology, Uppsala University, Sweden.

The aim was to investigate the effect of web-based patient information on patients' satisfaction with care during an F-FDG PET/CT examination, their knowledge about the examination and the image quality, compared with standard care, and to explore the usage of and satisfaction with web-based information. One hundred-forty-eight patients were recruited between October 2015 and December 2016 and randomly assigned to Standard Care (SC) or an Intervention Group (IG). SC received information about the F-FDG PET/CT examination according to standard care and IG also received access to web-based information about the examination. Read More

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http://dx.doi.org/10.2967/jnmt.118.213116DOI Listing
August 2018
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Current Status of F-FDG PET Brain Imaging in Patients with Dementia.

J Nucl Med Technol 2018 Dec 3;46(4):362-367. Epub 2018 Aug 3.

Department of Nuclear Medicine, Kuwait University Faculty of Medicine, Safat, Kuwait; and.

F-FDG PET brain imaging is commonly used in the early detection and differential diagnosis of various subtypes of dementias. F-FDG PET images are mainly evaluated visually, and semiquantitative analysis programs are also commonly used in many centers. However, visual and semiquantitative analysis carry certain limitations. Read More

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http://dx.doi.org/10.2967/jnmt.118.210237DOI Listing
December 2018
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Protocols for Harmonized Quantification and Noise Reduction in Low Dose Oncological F-FDG PET/CT Imaging.

J Nucl Med Technol 2018 Aug 3. Epub 2018 Aug 3.

Centro Regional de Ciências Nucleares (CRCN - NE)/ CNEN, Brazil.

Oncological F-FDG PET/CT acquisition and reconstruction protocols need to be optimized for both quantitative and detection tasks. To date, most studies have focused on either quantification or noise, leading to quantitative harmonization guidelines or appropriate noise levels. We developed and evaluated protocols that provide harmonized quantitation with optimal amount of noise as a function of acquisition parameters and body mass. Read More

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http://dx.doi.org/10.2967/jnmt.118.213405DOI Listing
August 2018
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Practical Considerations for Integrating PET/CT into Radiation Therapy Planning.

J Nucl Med Technol 2018 Dec 3;46(4):343-348. Epub 2018 Aug 3.

Department of Radiology, University of Tennessee Graduate School of Medicine, University of Tennessee Medical Center, Knoxville, Tennessee.

Over the past 20 y, PET/CT has had many technologic and developmental advancements for patient care. PET/CT has evolved from being used as a diagnosis and staging tool to now having an impact on treating cancer through a collaboration with radiation oncology. There are multiple considerations when integrating PET/CT into radiation therapy planning, such as the needs of the PET/CT center, the types of scans to offer, workflow considerations between the PET/CT center and the radiation therapy planning center, PET/CT center growth and demand on schedules, and the impact PET/CT will have on radiation treatment planning. Read More

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http://dx.doi.org/10.2967/jnmt.118.209452DOI Listing
December 2018
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