12,445 results match your criteria Journal of hypertension[Journal]


Influence of blood pressure on the effects of low-dose asprin in elderly patients with multiple atherosclerotic risks.

J Hypertens 2019 Jun;37(6):1301-1307

Graduate School of Advanced Science and Engineering, Waseda University, Tokyo, Japan.

Objective: We examined whether the efficacy of low-dose acetylsalicylic acid (aspirin) for primary prevention of cardiovascular events is influenced by blood pressure (BP) using data from patients aged 60-85 years with hypertension, dyslipidemia, and/or diabetes, but without cardiovascular disease of the Japanese Primary Prevention Project.

Methods: All patients had received aspirin (100 mg/day) or no aspirin. BP subgroups were defined as low (average SBP from the baseline to the year of the events <130 mmHg), moderate (≥130 and <140 mmHg), and high (≥140 mmHg). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002034DOI Listing

Nomograms to identify elevated blood pressure values and left ventricular hypertrophy in a paediatric population: American Academy of Pediatrics Clinical Practice vs. Fourth Report/European Society of Hypertension Guidelines.

J Hypertens 2019 Jun;37(6):1213-1222

School of Medicine and Surgery, University Milano - Bicocca.

Objective And Methods: The study aimed at evaluating, in a large sample of Italian children, the reclassification of blood pressure categories with the new U.S. nomograms, obtained in a population of normal-weight children (American Academy of Pediatrics Clinical Practice Guidelines, AAP-CPG), compared with the Fourth Report/European Society of Hypertension (ESH) nomograms. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002069DOI Listing
June 2019
1 Read

Aspirin for primary prevention in elderly hypertensive patients: to treat or not to treat?

J Hypertens 2019 Jun;37(6):1154-1156

Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002059DOI Listing

Highlights of the June issue.

Authors:
Giuseppe Mancia

J Hypertens 2019 Jun;37(6):1099-1101

Università Milano-Bicocca, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002124DOI Listing

Hypertension in a rural community in Sri Lanka: prevalence, associated factors and its effect on the renal profile.

J Hypertens 2019 Apr 15. Epub 2019 Apr 15.

World Health Organization, Country Office, Colombo, Sri Lanka.

Introduction: Chronic kidney disease (CKD) in which the disease cannot be attributed to any known cause is named CKD of uncertain aetiology (CKDu). The main aims of this analysis were to estimate the prevalence of hypertension and to identify the associated factors in a rural community vulnerable to CKDu and to identify the effect of hypertension on the renal profile among this community.

Methods: We conducted a cross-sectional representative population survey in five study areas in Anuradhapura district, a rural district in Sri Lanka. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002107DOI Listing

Leisure-time cross-country skiing is associated with lower incidence of hypertension: a prospective cohort study.

J Hypertens 2019 Apr 15. Epub 2019 Apr 15.

Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland.

Objective: The prospective relationship between cross-country skiing and hypertension is uncertain. We aimed to assess the associations of leisure time cross-country skiing habits with incident hypertension in a general population.

Methods: The frequency, average duration, and intensity of leisure cross-country skiing were assessed at baseline using a 12-month physical activity questionnaire in the Kuopio Ischemic Heart Disease prospective study of 1809 middle-aged men without hypertension. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002110DOI Listing

Efficacy and safety of dual combination therapy of blood pressure-lowering drugs as initial treatment for hypertension: a systematic review and meta-analysis of randomized controlled trials.

J Hypertens 2019 Apr 9. Epub 2019 Apr 9.

The George Institute for Global Health, University of New South Wales, Sydney, New South Wales.

Objective: To assess the efficacy and tolerability of dual combination of blood pressure (BP)-lowering drugs as initial treatment for hypertension.

Methods: MEDLINE, Embase, CENTRAL were searched until August 2017 for randomized, double-blind trials of dual combination therapy vs. monotherapy in adults with hypertension who were either treatment naïve or untreated for at least 4 weeks. Read More

View Article

Download full-text PDF

Source
http://Insights.ovid.com/crossref?an=00004872-900000000-9722
Publisher Site
http://dx.doi.org/10.1097/HJH.0000000000002096DOI Listing
April 2019
7 Reads
4.720 Impact Factor

Estimated 24-h urinary sodium and sodium-to-potassium ratio are predictors of kidney function decline in a population-based study.

J Hypertens 2019 Apr 5. Epub 2019 Apr 5.

Institute of Social and Preventive Medicine (IUMSP), Lausanne University Hospital (CHUV), Lausanne.

Background: The prevalence of chronic kidney disease (CKD) is increasing worldwide in part due to population ageing. Identifying risk factors for age-related kidney function decline could help in understanding mechanisms for kidney ageing. Sodium and potassium intakes are associated with CKD progression in the renal population, but little is known on their role in renal function decline [mean estimated glomerular filtration rate variation (ΔeGFR)] in the general adult population. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002098DOI Listing
April 2019
1 Read

Prevalence, awareness, treatment and control of hypertension in rural and urban communities in Latin American countries.

J Hypertens 2019 Apr 5. Epub 2019 Apr 5.

The Population Health Research Institute (PHRI), Hamilton, Ontario, Canada.

Objectives: The objective is to describe hypertension (HTN) prevalence, awareness, treatment and control in urban and rural communities in Latin America to inform public and policy-makers.

Methods: Cross-sectional analysis from urban (n = 111) and rural (n = 93) communities including 33 276 participants from six Latin American countries (Argentina, Brazil, Chile, Colombia, Peru and Uruguay) were included. HTN was defined as self-reported HTN on blood pressure (BP) medication or average BP over 140/90 mmHg, awareness as self-reported HTN, and controlled as those with BP under 140/90 mmHg. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002108DOI Listing
April 2019
1 Read
4.720 Impact Factor

The association of home and accurately measured office blood pressure with coronary artery calcification among general Japanese men.

J Hypertens 2019 Apr 5. Epub 2019 Apr 5.

Department of Public Health, Shiga University of Medical Science, Otsu.

Objective: We conducted a cross-sectional study to clarify whether home blood pressure (HBP) is more strongly associated with coronary artery calcification (CAC) than accurately measured office blood pressure (OBP) among the general population of Japanese men.

Methods: We analyzed the data of 919 Japanese male participants who were randomly selected from general population (mean age 64.5 years). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002080DOI Listing

Effects of blood pressure-lowering drugs in heart failure: a systematic review and meta-analysis of randomized controlled trials.

J Hypertens 2019 Apr 3. Epub 2019 Apr 3.

The George Institute for Global Health.

: We aimed to combine evidence from all heart failure trials that have investigated the effects of drugs with blood pressure (BP)-lowering properties to assess the extent to which such drugs reduce BP in heart failure, the association between the net change in BP between treatment arms and cause-specific outcomes and whether treatment effects (efficacy and safety) vary according to baseline BP. We conducted a systematic review and meta-analysis including randomized clinical trials of drugs with BP-lowering properties in patients with chronic heart failure with at least 300 patient-years follow-up. We included a total of 37 trials (91 950 patients) and showed that treatment with drugs with BP-lowering properties resulted in a small but significant decrease in SBP in patients with heart failure with no evidence that the efficacy and safety of those drugs varied according to baseline BP. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002094DOI Listing
April 2019
2 Reads
4.720 Impact Factor

Sympathetic neural overdrive in congestive heart failure and its correlates: systematic reviews and meta-analysis.

J Hypertens 2019 Apr 3. Epub 2019 Apr 3.

Consiglio Nazionale delle Ricerche-Istituto di Fisiologia Clinica, Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension, Reggio Calabria.

Background And Objectives: Sympathetic neural activation occurs in congestive heart failure (CHF). However, the small sample size of the microneurographic studies, heterogeneity of the patients examined, presence of comorbidities as well as confounders (including treatment) represented major weaknesses not allowing to identify the major features of the phoenomenon, particularly in mild CHF. This meta-analysis evaluated 2530 heart failure (CHF) patients recruited in 106 microneurographic studies. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002093DOI Listing

Prior exposure to placental ischemia causes increased salt sensitivity of blood pressure via vasopressin production and secretion in postpartum rats.

J Hypertens 2019 Apr 3. Epub 2019 Apr 3.

Department of Cardiovascular Medicine, Kyushu University Graduate School of Medical Sciences.

Objectives: Women with a history of preeclampsia exhibit increased salt sensitivity of blood pressure at postpartum, which might be responsible for their increased risk of future cardiovascular diseases. However, it is unclear whether preeclampsia can cause increased salt sensitivity at postpartum. Vasopressin may play a role in the pathogenesis of preeclampsia and salt-sensitive hypertension. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002091DOI Listing
April 2019
1 Read

Incremental prognostic value of global left atrial peak strain in women with new-onset gestational hypertension.

J Hypertens 2019 Apr 3. Epub 2019 Apr 3.

Cardiovascular Department, MultiMedica IRCCS, Milan, Italy.

Background: Left atrial strain and strain rate parameters, measured by bidimensional-speckle tracking echocardiography, have been proposed as predictors of atrial fibrillation, stroke, congestive heart failure and cardiovascular death. However, they have not yet been tested in hypertensive disorders of pregnancy. The aim of this study was to assess the prognostic role of global left atrial peak strain (GLAPS) in a population of pregnant women with new-onset hypertension in a medium-term follow-up. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002086DOI Listing
April 2019
3 Reads

Is the cardiovascular health of South Africans today comparable with African Americans 45 years ago?

J Hypertens 2019 Apr 3. Epub 2019 Apr 3.

Hypertension in Africa Research Team (HART), North-West University, Potchefstroom, South Africa.

Objectives: Hypertension occurs frequently among black populations around the world. In the United States (US) health system, interventions since the 1960s resulted in improvements in hypertension awareness, management and control among African Americans. This is in stark contrast to current health systems in African countries. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002082DOI Listing
April 2019
1 Read

Epigenetic modulation of tenascin C in the heart: implications on myocardial ischemia, hypertrophy and metabolism.

J Hypertens 2019 Apr 3. Epub 2019 Apr 3.

Ludwig Boltzmann Cluster for Cardiovascular Research at the Center for Biomedical Research, Medical University of Vienna, Vienna, Austria.

Background: Tenascin C (TN-C) is considered to play a pathophysiological role in maladaptive left ventricular remodeling. Yet, the mechanism underlying TN-C-dependent cardiac dysfunction remains elusive.

Method: The present study was designed to investigate the effect of hypoxia and hypertrophic stimuli on TN-C expression in H9c2 cells and its putative regulation by epigenetic mechanisms, namely DNA promoter methylation and microRNAs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002097DOI Listing
April 2019
2 Reads

Increased blood pressure is associated with increased carotid artery intima-media thickness in children with repaired coarctation of the aorta.

J Hypertens 2019 Apr 3. Epub 2019 Apr 3.

Division of Paediatric Cardiology, Department of Paediatrics, Western University.

Objectives: The intima-media thickness of the common carotid artery (cIMT) is a good noninvasive surrogate marker for cardiovascular disease. Regular cIMT monitoring in children with congenital heart disease has great potential. We sought to determine which anthropomorphic and haemodynamic variables were significantly associated with the cIMT in paediatric patients with obesity and children with repaired coarctation of the aorta (CoA). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002077DOI Listing
April 2019
1 Read
4.720 Impact Factor

Perioperative SBP changes during orthopedic surgery in the elderly: clinical implications.

J Hypertens 2019 Apr 3. Epub 2019 Apr 3.

Department of Cardiology, Asklepeion General Hospital.

Objectives: We aimed to determine SBP changes during the perioperative period of a scheduled knee surgery under regional anesthesia and the extent of perioperative (in-hospital) white-coat effect.

Methods: All patients (aged ≥60 years) underwent clinic SBP measurements during both cardiological and anesthesiological visits, while home SBP the week before admission was obtained. Clinic SBP was registered just before surgery, during surgery and reanimation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002085DOI Listing

Carotid body enlargement in hypertension and other comorbidities evaluated by ultrasonography.

J Hypertens 2019 Mar 29. Epub 2019 Mar 29.

Department of Cardiology, the Second Affiliated Hospital of Chongqing Medical University.

Background: Carotid body hyperactivity is important for sympathetic-related diseases and carotid body volume may partly reflect carotid bodies' activity. Our objective was to identify the association between carotid body volume and hypertension or other sympathetic-related diseases.

Methods: Consecutive individuals, undergoing carotid ultrasonography, who were eligible for the inclusion criteria were included. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002068DOI Listing
March 2019
2 Reads

Neurocognition in treatment-resistant hypertension: profile and associations with cardiovascular biomarkers.

J Hypertens 2019 May;37(5):1040-1047

Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham.

Background: Hypertension in midlife has been associated with increased risk of stroke and neurocognitive decline. Few studies, however, have examined neurocognition among individuals with treatment-resistant hypertension or potential mechanisms by which treatment-resistant hypertension may impair neurocognition.

Methods: We examined the pattern of neurocognitive impairment and potential mechanisms in a sample of 96 overweight adults with treatment-resistant hypertension, aged 41-81 years. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002002DOI Listing
May 2019
6 Reads

Rho kinase activity and atrial fibrillation: insights from chronic kidney disease and dialysis patients.

J Hypertens 2019 May;37(5):1096-1097

Department of Medicine, Nephrology, Dialisis and Transplantation Unit, University of Padova, Padova, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002054DOI Listing

Highlights of the May issue.

Authors:
Giuseppe Mancia

J Hypertens 2019 May;37(5):863-864

Università Milano-Bicocca, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002117DOI Listing

Effects of isometric resistance training on resting blood pressure: individual participant data meta-analysis.

J Hypertens 2019 Mar 18. Epub 2019 Mar 18.

School of Science and Technology, University of New England, Armidale, New South Wales, Australia.

Background: Previous meta-analyses based on aggregate group-level data report antihypertensive effects of isometric resistance training (IRT). However, individual participant data meta-analyses provide more robust effect size estimates and permit examination of demographic and clinical variables on IRT effectiveness.

Methods: We conducted a systematic search and individual participant data (IPD) analysis, using both a one-step and two-step approach, of controlled trials investigating at least 3 weeks of IRT on resting systolic, diastolic and mean arterial blood pressure. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002105DOI Listing

A pilot double-blind randomized placebo-controlled crossover pharmacodynamic study of the centrally active aminopeptidase A inhibitor, firibastat, in hypertension.

J Hypertens 2019 Mar 14. Epub 2019 Mar 14.

Laboratory of Central Neuropeptides in the Regulation of Body Fluid Homeostasis and Cardiovascular Functions, Center for Interdisciplinary Research in Biology, College de France, PSL Research University, INSERM U1050, CNRS UMR7241, Paris, France.

Objectives: We conducted a pilot multicenter double-blind randomized placebo-controlled crossover pharmacodynamic study to evaluate the blood pressure (BP) and the hormonal effects of firibastat, a first-in-class aminopeptidase A inhibitor prodrug, in patients with hypertension.

Methods: Thirty-four patients with daytime ambulatory BP of at least 135/85 mmHg and less than 170/105 mmHg, after a 2-week run-in period were randomly assigned to receive either firibastat (250 mg b.i. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002092DOI Listing

Trends in status of hypertension in rural northeast China: results from two representative cross-sectional surveys, 2013-2018.

J Hypertens 2019 Mar 14. Epub 2019 Mar 14.

Department of Cardiology, The First Hospital of China Medical University.

Objective: To investigate the long-term natural trends in the status of hypertension in rural northeast China from 2013 to 2018.

Methods: Two successive cross-sectional surveys were conducted in Liaoning rural areas in 2013 and 2018, which included 10 753 and 10 926 participants aged at least 40 years from different villages, respectively. A multistage, stratified, and cluster random sampling method was used to ensure that the samples of the two studies were representative. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002076DOI Listing
March 2019
1 Read

Management of supine hypertension in patients with neurogenic orthostatic hypotension: scientific statement of the American Autonomic Society, European Federation of Autonomic Societies, and the European Society of Hypertension.

J Hypertens 2019 Mar 14. Epub 2019 Mar 14.

Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.

: Supine hypertension commonly occurs in patients with neurogenic orthostatic hypotension due to autonomic failure. Supine hypertension promotes nocturnal sodium excretion and orthostatic hypotension, thus, interfering with quality of life. Perusal of the literature on essential hypertension and smaller scale investigations in autonomic failure patients also suggest that supine hypertension may predispose to cardiovascular and renal disease. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002078DOI Listing
March 2019
4.720 Impact Factor

Latin American Consensus on the management of hypertension in the patient with diabetes and the metabolic syndrome.

J Hypertens 2019 Jun;37(6):1126-1147

Istituto Auxologico Italiano, IRCCS, and Università degli Studi of Milan, Italy.

: The prevalence of hypertension, type 2 diabetes mellitus (DM2) and the metabolic syndrome continues to increase in Latin America, while the rates of diagnosis, treatment and control of these disorders remain low. The frequency of the risk factors that constitute the metabolic syndrome and are associated with an increased risk of cardiovascular disease has not diminished since the publication of the previous consensus. This document discusses the socioeconomic, demographic, environmental and cultural characteristics of most associated Latin American countries and partially explains the lack of better results in improving clinical and public health actions that allow high morbidity and mortality rates caused by cardiovascular diseases and DM2 to be reduced through programs aligned with the so-called precision medicine, which should be predictive, preventive, personalized and participatory. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002072DOI Listing
June 2019
1 Read

Blood pressure levels and risk of cardiovascular disease mortality among Japanese men and women: the Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC Study).

J Hypertens 2019 Mar 14. Epub 2019 Mar 14.

Public Health, Department of Social and Environmental Medicine, Osaka University Graduate School of Medicine, Suita, Japan.

Objective: To examine the association of blood pressure (BP) with cardiovascular mortality in real-world settings and investigate whether that association varied by use of antihypertensive medication at baseline.

Methods: Data from 27 728 Japanese men and women, aged 40-79 years, free of stroke, coronary heart disease, cancer, and kidney disease at entry (1988-1990) were used in this study. Mortality surveillance was completed through 2009, resulting in 449 800 person-years of follow-up. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002073DOI Listing
March 2019
1 Read

Short-term blood pressure variability outweighs average 24-h blood pressure in the prediction of cardiovascular events in hypertension of the young.

J Hypertens 2019 Mar 14. Epub 2019 Mar 14.

Department of Medicine, University of Perugia, Perugia, Italy.

Objective: The association of short-term blood pressure (BP) variability (BPV) with cardiovascular events (CVEs) is controversial. Aim of this study was to investigate whether BPV measured as weighted 24-h SD was associated with CVE in a prospective cohort study of young patients screened for stage 1 hypertension.

Methods: We performed 24-h ambulatory BP monitoring in 1206 participants aged 33. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002074DOI Listing

Relationship between vascular damage and left ventricular concentric geometry in patients undergoing coronary angiography: a multicenter prospective study.

J Hypertens 2019 Jun;37(6):1183-1190

Internal Medicine, University of Brescia & Spedali Civili Brescia.

Background: Vascular structural (intima-media thickness) and functional (carotid pulse wave velocity, cPWV) alterations are related to different patterns of left ventricular (LV) geometry in general population samples and in hypertensive patients. The relationship between vascular damage, evaluated by both echotracking ultrasound and coronary angiography, and LV geometry has not been prospectively analyzed.

Methods: In eight Italian centers, 399 consecutive patients, without history of prior coronary artery disease and with clinical indication to coronary angiography, prospectively underwent cardiac standard ultrasound examination for the evaluation of LV mass, indexed by height to 2. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002052DOI Listing
June 2019
3 Reads

Current assessment of pulse wave velocity: comprehensive review of validation studies.

J Hypertens 2019 Mar 14. Epub 2019 Mar 14.

Internal Medicine and Hypertension Division, Department of Medical Sciences, University of Torino, AOU Città della Salute e della Scienza di Torino.

Objective: Carotid-femoral pulse wave velocity (PWV) is considered the gold standard for arterial stiffness assessment in clinical practice. A large number of devices to measure PWV have been developed and validated. We reviewed different validation studies of PWV estimation techniques and assessed their conformity to the Artery Society Guidelines and the American Heart Association recommendations. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002081DOI Listing
March 2019
1 Read

Blood pressure, antihypertensive medication use, and risk of erectile dysfunction in men with type I diabetes.

J Hypertens 2019 May;37(5):1070-1076

Department of Urology and Diabetes Research Center, University of Washington, Seattle, Washington, USA.

Objective: To gain insight into the effect of blood pressure on the pathophysiology of diabetic erectile dysfunction, we determined the onset, severity and treatment of hypertension and risk of incident erectile dysfunction in men with type I diabetes.

Methods: This prospective cohort study included 692 men without prevalent erectile dysfunction in the Epidemiology of Diabetes Interventions and Complications study. Erectile dysfunction was assessed yearly for 16 years with a single question querying presence of impotence. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000001988DOI Listing
May 2019
1 Read

Fish and omega-3 fatty acid consumption and risk of hypertension.

J Hypertens 2019 Jun;37(6):1223-1229

Division of Aging, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

Background: Experimental studies suggest that omega-3 fatty acid have favorable effects on blood pressure (BP). However, data on the association of long-term dietary intake of omega-3 fatty acid or fish with risk of hypertension in healthy subjects are sparse. We examined whether fish or omega-3 fatty acid consumption was associated with incident hypertension in the Physicians' Health Study (PHS). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002062DOI Listing
June 2019
1 Read

Ultra-high sensitive C-reactive protein during normal pregnancy and in preeclampsia: a pilot study.

J Hypertens 2019 May;37(5):1012-1017

Department of Obstetrics and Gynaecology.

Introduction: Angiogenic and inflammatory factors have been shown to play an important role in the pathogenesis of preeclampsia. However, there is little information on their interaction. The aims of this study were to investigate the longitudinal pattern of inflammatory markers, such as interleukin-6 (IL-6) and C-reactive protein (CRP) using a novel ultra-high sensitive assay method (uhsCRP), and to explore their relationship with angiogenic factors such as placental growth factor (PLGF), soluble fms-like tyrosine kinase-1 (sFlt-1), and vascular endothelial growth factor (VEGF) in normal pregnancies and pregnancies complicated by preeclampsia. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002003DOI Listing
May 2019
1 Read

Redefining diuretics use in hypertension: why select a thiazide-like diuretic?

J Hypertens 2019 Mar 14. Epub 2019 Mar 14.

University College London, NIHR University College London Hospitals Biomedical Research Centre, London, Great Britain.

: Diuretics are listed in hypertension guidelines as one of three equally weighted first-line treatment options. In order to differentiate between antihypertensives, a lot of discussion has been directed at side effect profiles and as a result, has created a perhaps disproportionate fear of the metabolic effects that can be associated with diuretics. Data, however, show that the risk of a clinically meaningful change in laboratory parameters is very low, whereas the benefits of volume control and natriuresis are high and the reductions in morbidity and mortality are clinically significant. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002088DOI Listing
March 2019
4 Reads

A new approach to identifying hypertension-associated genes in the mesenteric artery of spontaneously hypertensive rats and stroke-prone spontaneously hypertensive rats.

J Hypertens 2019 Mar 14. Epub 2019 Mar 14.

Hirakata General Hospital for Developmental Disorders, Hirakata.

Objective: Hypertension is one of the most prevalent diseases in humans who live a modern lifestyle. Alongside more effective care, clarification of the genetic background of hypertension is urgently required. Gene expression in mesenteric resistance arteries of spontaneously hypertensive rats (SHR), stroke-prone SHR (SHRSP) and two types of renal hypertensive Wistar Kyoto rats (WKY), two kidneys and one clip renal hypertensive rat (2K1C) and one kidney and one clip renal hypertensive rat (1K1C), was compared using DNA microarrays. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002083DOI Listing
March 2019
3 Reads

Effect of acute maximal exercise on vasodilatory function and arterial stiffness in African-American and white adults.

J Hypertens 2019 Jun;37(6):1262-1268

Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, Illinois.

Introduction: African-Americans are at increased risk of cardiovascular disease compared with their white counterparts, potentially due to greater arterial stiffness and reduced vasodilatory capacity. Racial differences also exist in arterial stiffness and blood pressure (BP) following maximal aerobic exercise; African-Americans do not exhibit central post exercise BP reductions. Whether impaired vasodilatory function contributes to the lack of BP response is unknown. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002049DOI Listing
June 2019
1 Read

Coronary heart disease diagnosis by artificial neural networks including aortic pulse wave velocity index and clinical parameters.

J Hypertens 2019 Mar 11. Epub 2019 Mar 11.

Paris-Descartes University.

Background: Cardiovascular disease, such as coronary heart disease (CHD), are the main cause of mortality and morbidity worldwide. CHD is not entirely predicted by classic risk factors; however, they are preventable. Facing this major problem, the development of novel methods for CHD risk prediction is of practical interest. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002075DOI Listing
March 2019
2 Reads

Does the benefit from treating to lower blood pressure targets vary with age? A systematic review and meta-analysis.

J Hypertens 2019 Mar 11. Epub 2019 Mar 11.

Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey.

Background: Recommendations differ regarding how blood pressure targets should vary with age. Crucial to this controversy is whether treatment benefit varies with age.

Methods: Systematic searches were conducted for trials randomizing treatment in intensive arms to the recommended SBP targets: 120-140 mmHg. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002079DOI Listing
March 2019
4.720 Impact Factor

High-normal blood pressure and abnormal left ventricular geometric patterns: a meta-analysis.

J Hypertens 2019 Feb 11. Epub 2019 Feb 11.

Clinical Research Unit, Istituto Auxologico Italiano IRCCS.

Aim: The association between prehypertension (pre-HTN) and abnormal left ventricular (LV) geometric patterns is unclear. We performed a meta-analysis of echocardiographic studies aimed to provide a new piece of information on LV geometric alterations in untreated pre-HTN individuals.

Design: Studies were identified by crossing the following search terms: 'prehypertension,' 'high normal blood pressure,' 'heart,' 'LV hypertrophy' (LVH), 'LV geometry,' 'LV mass,' and 'echocardiography. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002063DOI Listing
February 2019
4 Reads

Reply.

J Hypertens 2019 Apr;37(4):861-862

Department of Public Health Sciences, School of Medicine, University of Virginia, Charlottesville, Virginia, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000002044DOI Listing
April 2019
1 Read

A hybrid 4-item Krousel-Wood Medication Adherence Scale predicts cardiovascular events in older hypertensive adults.

J Hypertens 2019 Apr;37(4):851-859

Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama, USA.

Background: There is a need for a brief, open access, self-report medication adherence scale that overcomes challenges of existing adherence tools, is associated with incident cardiovascular disease (CVD), and identifies low 'implementation' adherers to antihypertensive medications to facilitate blood pressure management.

Methods And Results: Antihypertensive medication adherence was assessed in a cohort of 1532 older hypertensive adults without prior CVD using the self-report 4-item Krousel-Wood Medication Adherence Scale (K-Wood-MAS-4), a hybrid tool developed to predict pharmacy refill and which captures four domains of adherence behavior: self-efficacy, physical function, intentional medication-taking, and forgetfulness. The 4-item scale categorized participants as low and high adherers using scores at least 1 and less than 1, respectively. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000001955DOI Listing
April 2019
4 Reads

Serum uric acid and resistance to antihypertensive treatment: data from the European Lacidipine Study on Atherosclerosis.

J Hypertens 2019 Apr;37(4):844-850

Department of Medicine and Surgery.

Aim: Whether increased serum uric acid (SUA) favours resistance to antihypertensive drugs is not clear.

Methods: The European Lacidipine Study on Atherosclerosis (ELSA) was a randomized, double-blind, multicenter trial comparing the effects of a 4-year treatment with either lacidipine or atenolol on progression of carotid atherosclerosis in patients with moderate hypertension. SUA was assessed at randomization and at the study end, office blood pressure (BP) was measured at each titration visit and every 6 months thereafter, ambulatory BP was measured at randomization and every year thereafter. Read More

View Article

Download full-text PDF

Source
http://Insights.ovid.com/crossref?an=00004872-201904000-0002
Publisher Site
http://dx.doi.org/10.1097/HJH.0000000000001951DOI Listing
April 2019
4 Reads

Optimal SBP targets in routine clinical care.

J Hypertens 2019 Apr;37(4):837-843

Norwich Medical School, University of East Anglia, Norwich, UK.

Objective: Compare outcomes of intensive treatment of SBP to less than 120 mmHg versus standard treatment to less than 140 mmHg in the US clinical Systolic Blood Pressure Intervention Trial (SPRINT) with similar hypertensive patients managed in routine primary care in the United Kingdom.

Methods: Hypertensive patients aged 50-90 without diabetes or chronic kidney disease (CKD) were selected in SPRINT and The Health Improvement Network (THIN) database. Patients were enrolled in 2010-2013 and followed-up to 2015 (SPRINT N = 4112; THIN N = 8631). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000001947DOI Listing
April 2019
2 Reads

Neurohumoral and ambulatory haemodynamic adaptations following isometric exercise training in unmedicated hypertensive patients.

J Hypertens 2019 Apr;37(4):827-836

School of Human and Life Sciences, Canterbury Christ Church University, Kent.

Objective: Hypertension remains the leading modifiable risk factor for cardiovascular disease. Isometric exercise training (IET) has been shown to be a useful nonpharmacological intervention for reducing resting blood pressure (BP). This study aimed to measure alterations in office BP, ambulatory BP, cardiac autonomic modulation and inflammatory and vascular biomarkers following a programme of IET in unmedicated hypertensive patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000001922DOI Listing
April 2019
3 Reads

Frequency of achieving a 'fit' cardiorespiratory fitness level and hypertension: a cohort study.

J Hypertens 2019 Apr;37(4):820-826

Department of Epidemiology and Biostatistics.

Objectives: Although maintaining cardiorespiratory fitness is encouraged to reduce the risk of hypertension, the level at, and length of time for which, individuals need to maintain fitness remains unclear. We examined the association between the frequency of achieving the recommended fitness levels of the 'Physical Activity Reference for Health Promotion 2013' and the risk of hypertension among Japanese men.

Methods: This cohort study was conducted in 6653 men without hypertension enrolled in 1986. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000001935DOI Listing

Agreement between 24-h dietary recalls and 24-h urine collections for estimating sodium intake in China, Japan, UK, USA: the International Study of Macro- and Micro-nutrients and Blood Pressure.

J Hypertens 2019 Apr;37(4):814-819

Division of Prevention and Community Health, National Center for Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Objective: The present study aims to compare 24-h dietary recalls with 24-h urine collections for the estimation of sodium intake at both population and individual levels in China, Japan, the United Kingdom (UK), and the United States of America (USA), using data from the International Study of Macro- and Micro-nutrients and Blood Pressure (INTERMAP).

Methods: Mean differences between 24-h dietary recalls and 24-h urine collections were calculated for their agreement in estimating sodium intake at the population level; relative and absolute differences as well as misclassification of salt intake groups (salt intake <6, 6-8.9, 9-11. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000001941DOI Listing
April 2019
2 Reads