2,676 results match your criteria Journal of cardiac failure[Journal]


Diuretic Responsiveness and its Prognostic Significance in Children with Heart Failure.

J Card Fail 2019 Apr 12. Epub 2019 Apr 12.

Department of Pediatrics, Sections of Nephrology and Critical Care Medicine, Baylor College of Medicine, Texas Children's Hospital, Houston, TX.

Background: Loop diuretics are considered first-line therapy for congestion in children with heart failure, though some patients remain volume overloaded during treatment. We sought to characterize loop diuretic responsiveness (DR) in children hospitalized with acute decompensated failure (ADHF) and to determine whether a decreased response was associated with worse outcomes.

Methods And Results: DR was calculated for 108 consecutive children ˂21 years of age who were hospitalized with ADHF. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10719164183123
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http://dx.doi.org/10.1016/j.cardfail.2019.03.019DOI Listing
April 2019
4 Reads

Noise Pollution is the Heart Failure Community's Biggest Threat.

J Card Fail 2019 Apr;25(4):225-226

University of Tennessee Graduate School of Medicine, Knoxville TN and Washington University, St. Louis MO.

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http://dx.doi.org/10.1016/j.cardfail.2019.03.015DOI Listing

The Promise of Machine Learning: When will it be delivered?

J Card Fail 2019 Apr 9. Epub 2019 Apr 9.

Governor's Chair, UTHSC-ORNL Center in Biomedical Informatics, Professor, UTHSC Department of Pediatrics, Memphis, TN.

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https://linkinghub.elsevier.com/retrieve/pii/S10719164193038
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http://dx.doi.org/10.1016/j.cardfail.2019.04.006DOI Listing
April 2019
3 Reads

Adrenergic Polymorphisms and Survival in African Americans with Heart Failure: Results from A-HeFT.

J Card Fail 2019 Apr 9. Epub 2019 Apr 9.

University of Pittsburgh School of Medicine.

Background: Polymorphisms in adrenergic signaling affect the molecular function of adrenergic receptors and related proteins. The β1 adrenergic receptor (ADRB1) Arg389Gly, G-protein receptor kinase type 5 (GRK5) Gln41Leu, G-protein β-3 subunit (GNB3) 825 C/T, and α2c deletion affect adrenergic tone, impact heart failure outcomes and differ in prevalence by ethnicity. Their combined effect within black cohorts remains unknown. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10719164183098
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http://dx.doi.org/10.1016/j.cardfail.2019.04.007DOI Listing
April 2019
4 Reads

Research Integrity.

Authors:
Peter Buttrick

J Card Fail 2019 Apr 8. Epub 2019 Apr 8.

University of Colorado. Electronic address:

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http://dx.doi.org/10.1016/j.cardfail.2019.04.005DOI Listing

Association between cardiorespiratory fitness and risk of heart failure: a meta-analysis.

J Card Fail 2019 Apr 8. Epub 2019 Apr 8.

Division of Sports and Rehabilitation Medicine, Ulm University Medical Center, Ulm, Germany.

Background: Evidence emerges that cardiorespiratory fitness (CRF) might be implicated in the development of heart failure (HF). This meta-analysis aimed to quantify the association between CRF exposed at baseline and HF risk with dose-response analysis and to assess whether CRF changes over time are correlated with alterations in HF risk.

Methods: Cohort studies that assessed the association between CRF and risk of HF in subjects without baseline HF were included. Read More

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http://dx.doi.org/10.1016/j.cardfail.2019.04.008DOI Listing

Prognostic Value of BNP Reduction during Hospitalization in Patients with Acute Heart Failure.

J Card Fail 2019 Apr 6. Epub 2019 Apr 6.

Department of Cardiovascular Medicine, Juntendo University, Tokyo, Japan; Cardiovascular Respiratory Sleep Medicine, Juntendo University Graduate School of Medicine, Juntendo University School of Medicine, Tokyo, Japan. Electronic address:

Background: Prognostication of patients discharged after acute heart failure (AHF) hospitalization remains challenging. Body weight (BW) reduction is often used as a surrogate marker of decongestion despite the paucity of evidence. We thought to test the hypothesis that B-type natriuretic peptide (BNP) reduction during hospitalization has independent prognostic value in AHF. Read More

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http://dx.doi.org/10.1016/j.cardfail.2019.04.004DOI Listing
April 2019
1 Read

"Drugs Do Not Work on Patients Who Do Not Take Them" Can We Do Better in Patient Adherence?

J Card Fail 2019 Apr 6. Epub 2019 Apr 6.

Cardiology Division, Massachusetts General Hospital, Boston, MA; Harvard Medical School, Boston, MA. Electronic address:

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http://dx.doi.org/10.1016/j.cardfail.2019.04.003DOI Listing

Sleeve Gastrectomy in obese, Zucker rats restores cardiac function and geometry towards a lean phenotype independent of weight-loss.

J Card Fail 2019 Apr 5. Epub 2019 Apr 5.

Department of Medicine, Medical College of Wisconsin, 8900 W. Doyne Avenue, Milwaukee, WI 53226.

Introduction: Bariatric surgery, including sleeve gastrectomy (SG), significantly improves cardiac geometry and function in patients with heart failure. In this study, we utilized the obese, Zucker rat as an animal model of heart failure with preserved ejection fraction (HFpEF) to test the hypothesis that a SG will improve cardiac function independent of weight loss.

Methods And Results: Obese, male Zucker rats underwent SG, pair-fed sham, or ad-lib sham surgery. Read More

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http://dx.doi.org/10.1016/j.cardfail.2019.04.001DOI Listing

Prognostic Implications of Changes in Amino-Terminal Pro-B-Type Natriuretic Peptide in Acute Decompensated Heart Failure: Insights from ASCEND-HF.

J Card Fail 2019 Apr 3. Epub 2019 Apr 3.

Heart and Vascular Institute, Falls Church, VA. Electronic address:

Background: Amino terminal pro-B-type natriuretic peptide (NTproBNP) is closely associated with prognosis in acute decompensated heart failure (ADHF). As a result, there has been great interest measuring it during the course of treatment. The prognostic implications in both short-term and follow-up changes in NTproBNP need further clarification. Read More

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http://dx.doi.org/10.1016/j.cardfail.2019.04.002DOI Listing
April 2019
1 Read

Improving outcomes for heart failure patients after discharge: Mind the Gap.

J Card Fail 2019 Mar 29. Epub 2019 Mar 29.

The Division of General Internal Medicine and the Heart Function Clinic, University of Alberta, Edmonton, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cardfail.2019.03.018DOI Listing

Sedentary Time and Cumulative Risk of Preserved and Reduced Ejection Fraction Heart Failure: From the Multi-Ethnic Study of Atherosclerosis.

J Card Fail 2019 Mar 28. Epub 2019 Mar 28.

University of North Florida, Jacksonville, FL.

Background: This study examined the relationship between self-reported sedentary time (ST) and the cumulative risk of heart failure with preserved ejection fraction (HFpEF) and reduced ejection fraction (HFrEF) using a diverse cohort of U.S. adults 45-84 years of age. Read More

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http://dx.doi.org/10.1016/j.cardfail.2019.03.017DOI Listing

Myocardial Contraction Fraction Predicts Cardiovascular Events in Patients with Hypertrophic Cardiomyopathy and Normal Ejection Fraction.

J Card Fail 2019 Mar 27. Epub 2019 Mar 27.

Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York, NY, USA.

Background: Myocardial contraction fraction (MCF), the ratio of left ventricular (LV) stroke volume to myocardial volume, is a novel parameter that can distinguish between pathologic and physiologic hypertrophy. However, its prognostic value in hypertrophic cardiomyopathy (HCM) has never been examined. The objective was to determine if MCF is associated with functional capacity and predicts adverse cardiovascular outcomes in patients with HCM and normal LV ejection fraction (EF). Read More

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http://dx.doi.org/10.1016/j.cardfail.2019.03.016DOI Listing
March 2019
6 Reads

Authors' reply to the comments of Joshua Fogel and Abhinav Saxena for our paper.

J Card Fail 2019 Mar 26. Epub 2019 Mar 26.

Department of Medicine, University of Chicago Medical Center, Chicago, Illinois.

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http://dx.doi.org/10.1016/j.cardfail.2019.03.013DOI Listing
March 2019
1 Read

Following The Scent of Microbes Within: the Heart-Gut Connection.

J Card Fail 2019 Mar 26. Epub 2019 Mar 26.

Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio. Electronic address:

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http://dx.doi.org/10.1016/j.cardfail.2019.03.014DOI Listing
March 2019
1 Read

REDUCTION OF LEFT VENTRICULAR DILATATION BEYOND THE FIRST YEAR FOLLOWING ANTERIOR MYOCARDIAL INFARCTION.

J Card Fail 2019 Mar 22. Epub 2019 Mar 22.

Unitat Coronària, Servei de Cardiologia and Servei de Medicina Nuclear, Hospital Universitari Vall d'Hebron, Barcelona, Spain.

Background: Reduction of left ventricular (LV) dilatation (RD) beyond the first year following STEMI is unknown. We investigated its potential occurrence in comparison with stationary (SD) or progressive dilatation (PD).

Methods: Perfusion gated-SPECT features at 1 and 3 years were evaluated in 168 3-year survivors of first anterior STEMI. Read More

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http://dx.doi.org/10.1016/j.cardfail.2019.03.012DOI Listing

Real-world prevalence of adverse events after initiating sacubitril/valsartan compared to angiotensin converting enzyme inhibitors or angiotensin receptor blockers in systolic heart failure.

J Card Fail 2019 Mar 20. Epub 2019 Mar 20.

University of Michigan Health System, 1500 E. Medical Center Dr., Ann Arbor, Michigan; University of Michigan College of Pharmacy, 428 Church St., Ann Arbor, Michigan. Electronic address:

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http://dx.doi.org/10.1016/j.cardfail.2019.03.011DOI Listing

High Transpulmonary Artery Gradient Obtained at the Time of Left Ventricular Assist Device Implantation Negatively Affects Survival After Cardiac Transplantation.

J Card Fail 2019 Mar 20. Epub 2019 Mar 20.

Division of Cardiology, Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York.

Aim: Preoperatively elevated pulmonary vascular resistance (PVR) is a contraindication to heart transplantation (HT). Transpulmonary pressure gradient (TPG) is one of the main variables used in PVR determination (ie, PVR = TPG/cardiac output). Unlike PVR, which is subject to the shortcoming of cardiac output estimation, TPG is directly measured. Read More

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http://dx.doi.org/10.1016/j.cardfail.2019.03.010DOI Listing
March 2019
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Transplant Volume is Associated with Graft Acceptance Threshold and Center Resource Availability.

J Card Fail 2019 Mar 18. Epub 2019 Mar 18.

Division of Cardiovascular Surgery, Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address:

Background: Heart transplant volume varies significantly among centers. We hypothesize that centers where the transplant team routinely accepts organs previously declined by other centers and where operating room availability is unrestricted will have higher transplant volumes.

Methods And Results: We utilized the potential transplant recipient sequence number in the United Network for Organ Sharing database as a surrogate for graft acceptance threshold and the number of transplants occurring on weekends and 8 major holidays as a marker of center resource availability. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10719164183033
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http://dx.doi.org/10.1016/j.cardfail.2019.03.009DOI Listing
March 2019
3 Reads

Increased Intra-abdominal Pressure Induces Acute Kidney Injury in an Experimental Model of Congestive Heart Failure.

J Card Fail 2019 Mar 14. Epub 2019 Mar 14.

Department of Physiology, Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology; Department of Laboratory Medicine, Rambam Health Care Campus, Haifa, Israel. Electronic address:

Background: Congestive heart failure (CHF) entails a complex interaction between the heart and the kidney that represents a clinical entity called cardiorenal syndrome (CRS). One of the mechanisms underlying CRS includes increased intra-abdominal pressure (IAP). We examined the effect of elevated IAP on kidney function in rats with low- and high-output CHF. Read More

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http://dx.doi.org/10.1016/j.cardfail.2019.03.008DOI Listing
March 2019
1 Read

Heart Failure Practice in Japan: Successful at Present, but Challenging in the Future.

Authors:
Hiroyuki Tsutsui

J Card Fail 2019 Mar;25(3):145-146

Department of Cardiovascular Medicine, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.cardfail.2019.03.001DOI Listing

Incidence of Heart Failure Among Immigrants to Ontario, Canada: A CANHEART Immigrant Study.

J Card Fail 2019 Mar 12. Epub 2019 Mar 12.

Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada; University of Toronto, Toronto, Ontario, Canada; Peter Munk Cardiac Centre and the Joint Department of Medical Imaging, University Health Network. Electronic address:

Background: Several known traditional cardiovascular risk factors contribute to the development of heart failure (HF); however, whether ethnicity is also an important predictor is not well-established. We determined the incidence of hospitalization for HF among ethnic groups in Ontario, Canada and examined differences in risk factor prevalence that may contribute to disparities in HF hospitalization incidence between groups.

Methods And Results: We conducted a retrospective observational study from 2008 to 2012 using a linked cohort derived from population-based health administrative, clinical and survey datasets. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10719164183035
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http://dx.doi.org/10.1016/j.cardfail.2019.03.006DOI Listing
March 2019
9 Reads

Nutrition, Obesity and Cachexia in Patients with Heart Failure: A Consensus Statement from the HFSA Scientific Statements Committee.

J Card Fail 2019 Mar 12. Epub 2019 Mar 12.

Cardiovascular Division, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

Dietary guidance for patients with heart failure (HF) has traditionally focused on sodium and fluid intake restriction, but dietary quality is frequently poor in patients with HF and may contribute to morbidity and mortality. Restrictive dietary counselling can lead to inadequate intake of macronutrients and micronutrients by patients with HF, with the potential for deficiencies of calcium, magnesium, zinc, iron, thiamine, vitamins D, E, K, and folate. Although inadequate intake and low plasma levels of micronutrients have been associated with adverse clinical outcomes, evidence supporting therapeutic repletion is limited. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10719164183091
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http://dx.doi.org/10.1016/j.cardfail.2019.03.007DOI Listing
March 2019
7 Reads

Heart Failure-Specific Relationship Between Muscle Sympathetic Nerve Activity and Aortic Wave Reflection.

J Card Fail 2019 Mar 9. Epub 2019 Mar 9.

University Health Network and Mount Sinai Hospital Division of Cardiology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada. Electronic address:

Background: Reflected arterial waves contribute to left ventricular (LV) afterload. Heart failure patients with reduced ejection fraction (HFrEF) are afterload sensitive and sympathetically activated. We tested the hypothesis that HFrEF patients exhibit a positive relationship between sympathetic vasoconstrictor discharge and aortic wave reflection. Read More

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http://dx.doi.org/10.1016/j.cardfail.2019.03.005DOI Listing

Trends in Utilization and Outcomes of Pulmonary Artery Catheterization in Heart Failure With and Without Cardiogenic Shock.

J Card Fail 2019 Mar 8. Epub 2019 Mar 8.

Division of Advanced Heart Failure and Transplant Cardiology, Vanderbilt University Medical Center, Nashville, Tennessee. Electronic address:

Background: The pulmonary artery catheter (PAC) has been used in a wide range of critically ill patients. It is not indicated for routine care of heart failure (HF), but its role in cardiogenic shock (CS) has not been clarified.

Methods And Results: We conducted a retrospective cohort study with the use of the National Inpatient Sample and identified a total of 9,431,944 adult patients admitted from 2004 to 2014 with the primary diagnosis of HF (n = 8,516,528) or who developed CS (n = 915,416) during the index hospitalization. Read More

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http://dx.doi.org/10.1016/j.cardfail.2019.03.004DOI Listing
March 2019
1 Read

Be Still My Beating Heart: Should Heart Rate Be a Target of Therapy After Heart Transplantation?

J Card Fail 2019 Apr 8;25(4):257-258. Epub 2019 Mar 8.

Division of Cardiology, Department of Medicine, Washington University School of Medicine, St. Louis, MO.

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http://dx.doi.org/10.1016/j.cardfail.2019.03.003DOI Listing

Statistical Analyses of Echocardiographic Predictors of Hemodynamics in Patients Supported With Left Ventricular Assist Devices.

J Card Fail 2019 Mar 6. Epub 2019 Mar 6.

Department of Cardiology, Maimonides Medical Center, Brooklyn, New York.

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http://dx.doi.org/10.1016/j.cardfail.2019.03.002DOI Listing

Trends in In-Hospital Mortality, Length of Stay, Nonroutine Discharge, and Cost Among End-Stage Renal Disease Patients on Dialysis Hospitalized With Heart Failure (2001-2014).

J Card Fail 2019 Mar 4. Epub 2019 Mar 4.

Division of Cardiovascular Diseases, University of Iowa Hospitals and Clinics, Iowa City, Iowa. Electronic address:

Background: Heart failure (HF) is a common cause of morbidity and mortality among end-stage renal disease (ESRD) patients on dialysis. We aimed to assess the trends and outcomes in primary and secondary HF hospitalizations among ESRD patients with the use of a nationally representative database.

Methods And Results: We analyzed data from the National Inpatient Sample and the US Census Bureau to calculate annual national rates of in-hospital mortality, length of stay, disposition with a focus on nonroutine discharge (discharge to a health care facility rather than to home), and adjusted median cost among patients with ESRD on dialysis with primary or secondary HF admissions from 2001 to 2014. Read More

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http://dx.doi.org/10.1016/j.cardfail.2019.02.020DOI Listing

Serial Cardiac FDG-PET for the Diagnosis and Therapeutic Guidance of Patients With Cardiac Sarcoidosis.

J Card Fail 2019 Apr 27;25(4):307-311. Epub 2019 Feb 27.

Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California. Electronic address:

Background: Cardiac fluorodeoxyglucose positron-emission tomography (FDG-PET) has emerged as a standard imaging modality for the diagnosis of cardiac sarcoidosis (CS); however, there is a scarcity of data on the use of serial FDG-PET to guide immunosuppressive therapy. The aim of this work was to report our experience using serial FDG-PET for the diagnosis and management of patients with CS, focusing on its utility in ongoing immunosuppression management.

Methods And Results: We studied consecutive patients with CS managed at Stanford University from 2010 to 2017. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10719164193020
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http://dx.doi.org/10.1016/j.cardfail.2019.02.018DOI Listing
April 2019
5 Reads

Pulmonary Vascular Resistance Is Associated With Brachial-Ankle Pulse-Wave Velocity and Adverse Clinical Outcomes in Patients With Heart Failure With Preserved Ejection Fraction.

J Card Fail 2019 Feb 27. Epub 2019 Feb 27.

Department of Internal Medicine II, Faculty of Medicine, University of Yamanashi, Chuo, Japan.

Background: The precise mechanisms underlying the high prevalence of pulmonary hypertension (PH) with increased pulmonary vascular resistance (PVR) in heart failure with preserved ejection fraction (HFpEF) remain largely unknown. Measurements of brachial-ankle pulse wave velocity (baPWV) have been shown to be useful for risk assessment in HF patients. Thus, this study sought to define the association of PVR with baPWV and clinical outcomes in HFpEF. Read More

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http://dx.doi.org/10.1016/j.cardfail.2019.02.019DOI Listing
February 2019

Prediction of Survival in Asian Patients Hospitalized With Heart Failure: Validation of the OPTIMIZE-HF Risk Score.

J Card Fail 2019 Feb 26. Epub 2019 Feb 26.

Department of Cardiology, National Heart Centre Singapore, Singapore; Duke-NUS Medical School, Singapore.

Background: Risk scores predicting in-patient mortality in heart failure patients have not been designed specifically for Asian patients. We aimed to validate and recalibrate the OPTIMIZE-HF risk model for in-hospital mortality in a multiethnic Asian population hospitalized for heart failure.

Methods And Results: Data from the Singapore Cardiac Databank Heart Failure on patients admitted for heart failure from January 1, 2008, to December 31, 2013, were included. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10719164183090
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http://dx.doi.org/10.1016/j.cardfail.2019.02.016DOI Listing
February 2019
2 Reads

Exercise Ventilatory Efficiency in Older and Younger Heart Failure Patients With Preserved Ejection Fraction.

J Card Fail 2019 Apr 27;25(4):278-285. Epub 2019 Feb 27.

Department of Cardiovascular Medicine, Mayo Clinic, Rochester Minnesota.

Background: Patients with heart failure with preserved ejection fraction (HFpEF) exhibit pulmonary abnormalities, but the studies to date have reported wide variability in the ventilatory equivalent for carbon dioxide (V̇/V̇CO) slope. It is possible that aging may contribute to that variability. We sought to compare ventilatory efficiency and its components in older and younger HFpEF patients during exercise. Read More

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http://dx.doi.org/10.1016/j.cardfail.2019.02.015DOI Listing
April 2019
1 Read

When Payment Models Distort Perceptions and Care Delivery forPatients With Heart Failure.

J Card Fail 2019 Apr 26;25(4):227-229. Epub 2019 Feb 26.

Division of Cardiology, Veteran Affairs Greater Los Angeles Healthcare System, Los Angeles, California. Electronic address:

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http://dx.doi.org/10.1016/j.cardfail.2019.02.017DOI Listing
April 2019
3.051 Impact Factor

Characterization of Sympathetic Innervation in Heart Failure With Preserved Ejection Fraction.

J Card Fail 2019 Apr 26;25(4):314-315. Epub 2019 Feb 26.

University of Utah Health Sciences Center, Salt Lake City, Utah; George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, Utah. Electronic address:

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http://dx.doi.org/10.1016/j.cardfail.2019.02.014DOI Listing

Impact of QRS Duration and Ventricular Pacing on Clinical and Arrhythmic Outcomes in Continuous Flow Left Ventricular Assist Device Recipients: A Multicenter Study.

J Card Fail 2019 Feb 21. Epub 2019 Feb 21.

University of Florida, Gainesville, Florida.

Objectives: Wide QRS duration and ventricular pacing are common in recipients of continuous-flow left ventricular assist devices (CF-LVADs) but their impact on outcomes remains unclear. We assessed the clinical and arrhythmic outcomes of CF-LVAD patients with wide QRS or right ventricular (RV) pacing at baseline, compared with those with narrow QRS and those with continued cardiac resynchronization therapy (CRT).

Methods And Results: A total of 520 patients (57 ± 13 years) with an implantable cardioverter-defibrillator (ICD) (n = 240) or CRT-defibrillator (n = 280) who underwent CF-LVAD implantation at 5 centers in 2007-2015 were studied. Read More

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http://dx.doi.org/10.1016/j.cardfail.2019.02.013DOI Listing
February 2019
3 Reads

Comparative Analysis of Established Risk Scores and Novel Hemodynamic Metrics in Predicting Right Ventricular Failure in Left Ventricular Assist Device Patients.

J Card Fail 2019 Feb 18. Epub 2019 Feb 18.

Division of Cardiovascular Medicine, University of Virginia Health System, Charlottesville, Virginia. Electronic address:

Background: Right ventricular failure (RVF) portends poor outcomes after left ventricular assist device (LVAD) implantation. Although numerous RVF predictive models have been developed, there are few independent comparative analyses of these risk models.

Methods And Results: RVF was defined as use of inotropes for >14days, inhaled pulmonary vasodilators for >48hours or unplanned right ventricular mechanical support postoperatively during the index hospitalization. Read More

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http://dx.doi.org/10.1016/j.cardfail.2019.02.011DOI Listing
February 2019

Dancing Cats, Heart Failure, and Circulating Troponin.

J Card Fail 2019 Apr 16;25(4):238-239. Epub 2019 Feb 16.

Libin Cardiovascular Institute and University of Calgary Medical Centre, Calgary, Alberta, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cardfail.2019.02.012DOI Listing

The Positives of Negative Data.

J Card Fail 2019 02;25(2):77

University of Washington, Department of Medicine, Box 358050, Seattle, WA 98109. Electronic address:

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http://dx.doi.org/10.1016/j.cardfail.2019.01.010DOI Listing
February 2019

Expression of Concern.

Authors:
Paul J Hauptman

J Card Fail 2019 02;25(2):143

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http://dx.doi.org/10.1016/j.cardfail.2019.01.011DOI Listing
February 2019

Eyeing Autonomic Dysregulation in Heart Failure.

J Card Fail 2019 Mar 12;25(3):164-165. Epub 2019 Feb 12.

MetroHealth Campus of Case Western University School of Medicine, Cleveland, OH. Electronic address:

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http://dx.doi.org/10.1016/j.cardfail.2019.02.008DOI Listing

(Pro)renin Receptor Blockade Ameliorates Heart Failure Caused by Chronic Kidney Disease.

J Card Fail 2019 Apr 13;25(4):286-300. Epub 2019 Feb 13.

Department of Cardiology, Gifu University Graduate School of Medicine, Gifu, Japan.

Background: The (pro)renin receptor [(P)RR)] is involved in the activation of local renin-angiotensin system and subsequent development of cardiovascular disease. We investigated the therapeutic effect of a (P)RR blocker, handle-region peptide (HRP), on chronic kidney disease (CKD)-associated heart failure.

Methods And Results: CKD was induced in C57BL/6J mice by means of five-sixths nephrectomy. Read More

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http://dx.doi.org/10.1016/j.cardfail.2019.02.009DOI Listing
April 2019
2 Reads

National Outcomes in Hospitalized Patients With Cancer and Comorbid Heart Failure.

J Card Fail 2019 Feb 12. Epub 2019 Feb 12.

Division of Cardiology, UCLA Cardio-Oncology Program, David Geffen School of Medicine at UCLA, Los Angeles, California; VA Greater Los Angeles Healthcare System, Los Angeles, California. Electronic address:

Background: Heart failure (HF) and cancer are a significant cause of morbidity and mortality in the US. Due to overlapping risk factors, these two conditions often coexist.

Methods: We sought to describe the national burden of HF for hospitalized patients with cancer. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10719164183111
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http://dx.doi.org/10.1016/j.cardfail.2019.02.007DOI Listing
February 2019
4 Reads
3.051 Impact Factor

The Role of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Duchenne Muscular Dystrophy Cardiomyopathy.

J Card Fail 2019 Apr 11;25(4):259-267. Epub 2019 Feb 11.

Thomas P Graham Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee; Division of Cardiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.

Background: Cardiomyopathy is the leading cause of death in Duchenne muscular dystrophy (DMD). Standard cardiac biomarkers are poor indicators of DMD cardiovascular disease. Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) regulate collagen turnover. Read More

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http://dx.doi.org/10.1016/j.cardfail.2019.02.006DOI Listing
April 2019
2 Reads

[Reply to Notarius].

J Card Fail 2019 Mar 10;25(3):223. Epub 2019 Feb 10.

Departments of Medicine and Radiology, Washington University School of Medicine, St Louis, Missouri.

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http://dx.doi.org/10.1016/j.cardfail.2019.02.001DOI Listing
March 2019
1 Read

Diastolic Intra-Left Ventricular Pressure Difference During Exercise: Strong Determinant and Predictor of Exercise Capacity in Patients With Heart Failure.

J Card Fail 2019 Apr 10;25(4):268-277. Epub 2019 Feb 10.

Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

Background: Although the enhancement of early-diastolic intra-left ventricular pressure difference (IVPD) during exercise is considered to maintain exercise capacity, little is known about their relationship in heart failure (HF).

Methods And Results: Cardiopulmonary exercise testing and exercise-stress echocardiography were performed in 50 HF patients (left ventricular [LV] ejection fraction 39 ± 15%). Echocardiographic images were obtained at rest and submaximal and peak exercise. Read More

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http://dx.doi.org/10.1016/j.cardfail.2019.02.005DOI Listing
April 2019
1 Read

Driving Pulseless: A Driving Survey of Patients With Left Ventricular Assist Devices and Their Providers.

J Card Fail 2019 Mar 10;25(3):220-221. Epub 2019 Feb 10.

University of Rochester Medical Center, Rochester, New York.

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http://dx.doi.org/10.1016/j.cardfail.2019.02.003DOI Listing

Resting Oxygen Consumption and Heart Failure: Importance of Measurement for Determination of Cardiac Output With the Use of the Fick Principle.

J Card Fail 2019 Feb 10. Epub 2019 Feb 10.

Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan.

Background: Resting oxygen consumption (VO) is often estimated and frequently used to guide therapeutic decisions in symptomatic heart failure (HF) patients. The relationship between resting VO and symptomatic HF and the accuracy of estimations of VO in this population are unknown.

Methods And Results: We performed a cross-sectional study of HF patients (n = 691) and healthy control subjects (n = 77). Read More

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http://dx.doi.org/10.1016/j.cardfail.2019.02.004DOI Listing
February 2019
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Empagliflozin Targeting the Real-World Heart Failure Population.

J Card Fail 2019 Mar 10;25(3):218-219. Epub 2019 Feb 10.

Unidade de Insuficiência Cardíaca, Serviço de Medicina III, Hospital de São Francisco Xavier, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal; NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal.

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http://dx.doi.org/10.1016/j.cardfail.2019.02.002DOI Listing
March 2019
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Accuracy of Administrative Coding to Identify Reduced and Preserved Left Ventricular Ejection Fraction.

J Card Fail 2019 Feb 10. Epub 2019 Feb 10.

Keck School of Medicine of the University of Southern California.

Background: Coding of systolic function in heart failure is important, but the accuracy is uncertain.

Methods And Results: We used data from a chart review of VA heart failure hospitalizations from 2006 to 2013. Trained abstractors determined the documented diagnosis of heart failure and the left ventricular ejection fraction (LVEF). Read More

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http://dx.doi.org/10.1016/j.cardfail.2019.01.019DOI Listing
February 2019
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