8 results match your criteria Journal of biomedicine & biotechnology[Journal]

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Muscle and Bone Mass Loss in the Elderly Population: Advances in diagnosis and treatment.

J Biomed (Syd) 2018 ;3:40-49

Research and Development Service (151), VA Caribbean Healthcare System, San Juan PR, USA.

Aging is the result of different functional changes leading to a substantial reduction of all human capabilities. A variety of anatomical and physiological changes occur with advancing age. These changes are more evident in the elderly population. Read More

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http://dx.doi.org/10.7150/jbm.23390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261527PMC
January 2018
1 Read

Nanoparticle Design Strategies for Effective Cancer Immunotherapy.

J Biomed (Syd) 2017 ;2(2):64-77

Department of Chemical Engineering, University of Massachusetts Lowell, USA.

Cancer immunotherapy is a rapidly evolving and paradigm shifting treatment modality that adds a strong tool to the collective cancer treatment arsenal. It can be effective even for late stage diagnoses and has already received clinical approval. Tumors are known to not only avoid immune surveillance but also exploit the immune system to continue local tumor growth and metastasis. Read More

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http://dx.doi.org/10.7150/jbm.18877DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426812PMC
January 2017
15 Reads

Increasing efficiency of preclinical research by group sequential designs.

PLoS Biol 2017 03 10;15(3):e2001307. Epub 2017 Mar 10.

Center for Stroke Research, Charité Universitätsmedizin Berlin, Berlin, Germany.

Despite the potential benefits of sequential designs, studies evaluating treatments or experimental manipulations in preclinical experimental biomedicine almost exclusively use classical block designs. Our aim with this article is to bring the existing methodology of group sequential designs to the attention of researchers in the preclinical field and to clearly illustrate its potential utility. Group sequential designs can offer higher efficiency than traditional methods and are increasingly used in clinical trials. Read More

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http://dx.doi.org/10.1371/journal.pbio.2001307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345756PMC
March 2017
28 Reads

Chiral Antioxidant-based Gold Nanoclusters Reprogram DNA Epigenetic Patterns.

Sci Rep 2016 09 16;6:33436. Epub 2016 Sep 16.

Institute of Nano Biomedicine and Engineering, Shanghai Engineering Center for Intelligent Diagnosis and Treatment Instrument, Department of Instrument Science and Engineering, Key Lab. for Thin Film and Microfabrication Technology of Ministry of Education, School of Electronic Information and Electronic Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.

Epigenetic modifications sit 'on top of' the genome and influence DNA transcription, which can force a significant impact on cellular behavior and phenotype and, consequently human development and disease. Conventional methods for evaluating epigenetic modifications have inherent limitations and, hence, new methods based on nanoscale devices are needed. Here, we found that antioxidant (glutathione) chiral gold nanoclusters induce a decrease of 5-hydroxymethylcytosine (5hmC), which is an important epigenetic marker that associates with gene transcription regulation. Read More

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http://dx.doi.org/10.1038/srep33436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025748PMC
September 2016
31 Reads
5.080 Impact Factor

A new computational method for automatic dental measurement: The case of maxillary central incisor.

Comput Biol Med 2016 Mar 22;70:202-209. Epub 2016 Jan 22.

Department of Life, Health & Environment Sciences, University of L'Aquila, L'Aquila, Italy.

This paper proposes a new automatic approach to determine the accurate measure of human teeth. The aim of the proposed computer based method is to reduce inaccuracy of measurement with respect to traditional approaches. Starting from a 3D model of the teeth which is obtained from 3D scanning, the method algorithmically evaluates the most important dimensional features detectable in central incisors. Read More

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http://dx.doi.org/10.1016/j.compbiomed.2016.01.018DOI Listing

A new method for the automatic identification of the dimensional features of vertebrae.

Comput Methods Programs Biomed 2015 Aug 5;121(1):36-48. Epub 2015 May 5.

Department of Industrial and Information Engineering, and of Economics, L'Aquila, Italy. Electronic address:

In this paper a new automatic approach to determine the accurate measure of human vertebrae is proposed. The aim is to speed up the measurement process and to reduce the uncertainties that typically affect the measurement carried out by traditional approaches. The proposed method uses a 3D model of the vertebra obtained from CT-scans or 3D scanning, from which some characteristic dimensions are detected. Read More

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http://dx.doi.org/10.1016/j.cmpb.2015.04.003DOI Listing

Integrated care pathways for airway diseases (AIRWAYS-ICPs).

Authors:
J Bousquet A Addis I Adcock I Agache A Agusti A Alonso I Annesi-Maesano J M Anto C Bachert C E Baena-Cagnani C Bai A Baigenzhin C Barbara P J Barnes E D Bateman L Beck A Bedbrook E H Bel O Benezet K S Bennoor M Benson M Bernabeu-Wittel M Bewick C Bindslev-Jensen H Blain F Blasi M Bonini S Bonini L P Boulet A Bourdin R Bourret P J Bousquet C E Brightling A Briggs J Brozek R Buhl A Bush D Caimmi M Calderon P Calverley P A Camargos T Camuzat G W Canonica K H Carlsen T B Casale M Cazzola A M Cepeda Sarabia A Cesario Y Z Chen E Chkhartishvili N H Chavannes R Chiron A Chuchalin K F Chung L Cox G Crooks M G Crooks A A Cruz A Custovic R Dahl S E Dahlen F De Blay T Dedeu D Deleanu P Demoly P Devillier A Didier A T Dinh-Xuan R Djukanovic D Dokic H Douagui R Dubakiene S Eglin F Elliot R Emuzyte L Fabbri A Fink Wagner M Fletcher W J Fokkens J Fonseca A Franco P Frith A Furber M Gaga J Garcés J Garcia-Aymerich A Gamkrelidze S Gonzales-Diaz F Gouzi M A Guzmán T Haahtela D Harrison M Hayot L G Heaney J Heinrich P W Hellings J Hooper M Humbert M Hyland G Iaccarino D Jakovenko J R Jardim C Jeandel C Jenkins S L Johnston O Jonquet G Joos K S Jung O Kalayci S Karunanithi T Keil N Khaltaev V Kolek M L Kowalski I Kull P Kuna V Kvedariene L T Le K C Lodrup Carlsen R Louis W MacNee A Mair I Majer P Manning E de Manuel Keenoy M R Masjedi E Melen E Melo-Gomes A Menzies-Gow G Mercier J Mercier J P Michel N Miculinic F Mihaltan B Milenkovic M Molimard I Momas A Montilla-Santana M Morais-Almeida M Morgan M N'Diaye S Nafti K Nekam A Neou L Nicod R O'Hehir K Ohta P Paggiaro S Palkonen S Palmer N G Papadopoulos A Papi G Passalacqua I Pavord B Pigearias D Plavec D S Postma D Price K F Rabe F Radier Pontal J Redon S Rennard J Roberts J M Robine J Roca N Roche F Rodenas A Roggeri C Rolland J Rosado-Pinto D Ryan B Samolinski M Sanchez-Borges H J Schünemann A Sheikh M Shields N Siafakas Y Sibille T Similowski I Small O Sola-Morales T Sooronbaev R Stelmach P J Sterk T Stiris P Sud V Tellier T To A Todo-Bom M Triggiani R Valenta A L Valero A Valiulis E Valovirta E Van Ganse O Vandenplas T Vasankari J Vestbo G Vezzani G Viegi L Visier C Vogelmeier T Vontetsianos R Wagstaff U Wahn B Wallaert B Whalley M Wickman D M Williams N Wilson B P Yawn P K Yiallouros A Yorgancioglu O M Yusuf H J Zar N Zhong M Zidarn T Zuberbier

Eur Respir J 2014 Aug 12;44(2):304-23. Epub 2014 Jun 12.

GALEN, Global Allergy and Asthma European Network Charité University Hospital, Allergy Centre Charité, Berlin, Germany.

The objective of Integrated Care Pathways for Airway Diseases (AIRWAYS-ICPs) is to launch a collaboration to develop multi-sectoral care pathways for chronic respiratory diseases in European countries and regions. AIRWAYS-ICPs has strategic relevance to the European Union Health Strategy and will add value to existing public health knowledge by: 1) proposing a common framework of care pathways for chronic respiratory diseases, which will facilitate comparability and trans-national initiatives; 2) informing cost-effective policy development, strengthening in particular those on smoking and environmental exposure; 3) aiding risk stratification in chronic disease patients, using a common strategy; 4) having a significant impact on the health of citizens in the short term (reduction of morbidity, improvement of education in children and of work in adults) and in the long-term (healthy ageing); 5) proposing a common simulation tool to assist physicians; and 6) ultimately reducing the healthcare burden (emergency visits, avoidable hospitalisations, disability and costs) while improving quality of life. In the longer term, the incidence of disease may be reduced by innovative prevention strategies. Read More

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http://erj.ersjournals.com/content/erj/44/2/304.full.pdf
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http://erj.ersjournals.com/cgi/doi/10.1183/09031936.00014614
Publisher Site
http://dx.doi.org/10.1183/09031936.00014614DOI Listing
August 2014
11 Reads
33 Citations
7.640 Impact Factor

[The role of imagination in modern medicine].

Authors:
Heinz Schott

Ber Wiss 2004 Jun;27(2):99-108

In Renaissance and early modern times, the concept of imagination (Latin imaginatio) was essential for the (natural) philosophical explanation of magic processes, especially in the anthropology of Paracelsus. He assumed that imagination was a natural vital power including cosmic, mental, phychical, and physical dimensions. The Paracelsians criticized traditional humor pathology ignoring their theory of' 'natural magic'. Read More

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http://dx.doi.org/10.1002/bewi.200401001DOI Listing
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