4,129 results match your criteria Journal of biomechanical engineering[Journal]


STUDIES ON RAMBERG-OSGOOD EQUATION PARAMETERS OF CORTICAL BONE.

J Biomech Eng 2019 Feb 19. Epub 2019 Feb 19.

Department of Mechanical Engineering and Division of Biomedical Engineering, University of Saskatchewan, Saskatoon, S7N5A9, Canada.

Bone is a complex material that exhibits an amount of plasticity before bone fracture takes place, where the non-linear relationship between stress and strain is of importance to understanding the mechanism behind the fracture. This brief presents our study on the examination of the stress-stain relationship of bovine femoral cortical bone and the relationship representation by employing the Ramberg-Osgood (R-O) equation. Samples were taken and prepared from different locations (upper, middle and lower) of bone diaphysis and were then subjected to the uniaxial tensile tests under longitudinal and transverse loading conditions, respectively. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042901DOI Listing
February 2019

Mechanical response of human muscle at intermediate strain rates.

J Biomech Eng 2019 Feb 19. Epub 2019 Feb 19.

School of Aeronautics and Astronautics, Purdue University, West Lafayette, IN, 47907, USA; School of Materials Engineering, Purdue University, West Lafayette, IN, 47907, USA.

We experimentally determined the tensile stress-strain response of human muscle along fiber direction and compressive stress-strain response transverse to fiber direction at intermediate strain rates. A hydraulically driven materials testing system with a dynamic testing mode was used to perform the tensile and compressive experiments on human muscle tissue. Experiments at quasi-static strain rates were also conducted to investigate the strain-rate effects over a wider range. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042900DOI Listing
February 2019

Computationally optimizing the compliance of multilayered biomimetic tissue engineered vascular grafts.

J Biomech Eng 2019 Feb 19. Epub 2019 Feb 19.

ASME Member, Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States, McGowan Institute for Regenerative Medicine, 300 Technology Drive, Pittsburgh, PA, United State 15219.

Coronary artery bypass grafts used to treat coronary artery disease often fail due to compliance mismatch. In this study, we have developed an experimental/computational approach to fabricate an acellular biomimetic hybrid tissue engineered vascular graft composed of alternating layers of electrospun porcine gelatin/polycaprolactone (PCL) and human tropoelastin/PCL blends with the goal of compliance-matching to rat abdominal aorta, while maintaining specific geometrical constraints. Polymeric blends at three different gelatin:PCL (G:PCL) and tropoelastin:PCL (T:PCL) ratios (80:20, 50:50 and 20:80) were mechanically characterized. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042902DOI Listing
February 2019

Numerical study of incomplete stent apposition caused by deploying undersized stent in arteries with elliptical cross-sections.

J Biomech Eng 2019 Feb 19. Epub 2019 Feb 19.

Department of Mechanical Engineering, The University of Melbourne, Department of Mechanical Engineering, Melbourne School of Engineering, The University of Melbourne, Victoria 3010, Australia.

Incomplete stent apposition (ISA) is one of the causes leading to post-stent complications, which can be found when an undersized or under-expanded stent is deployed at lesions. Previous research efforts have focused on ISA in idealized coronary arterial geometry with circular cross-sections. However, arterial cross-section eccentricity plays an important role in both location and severity of ISA. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042899DOI Listing
February 2019

Soslowsky Sentiments: HR Lissner Medal Presentation.

Authors:
Louis Soslowsky

J Biomech Eng 2019 Feb 19. Epub 2019 Feb 19.

University of Pennsylvania, McKay Orthopaedic Research Laboratory, 3450 Hamilton Walk; 307A Stemmler Hall, Philadelphia, PA 19104-6081.

This paper generally follows the presentation I gave at the 2018 World Congress of Biomechanics in Dublin, Ireland in recognition of the receipt of the H.R. Lissner Medal from the American Society of Mechanical Engineers. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042896DOI Listing
February 2019

Journal of Biomechanical Engineering Legacy Paper 2018.

J Biomech Eng 2019 Feb 19. Epub 2019 Feb 19.

Department of Mechanical Engineering, University of Minnesota at Minneapolis, Minneapolis, MN 55455.

The Journal of Biomechanical Engineering has contributed to biomechanical engineering field since 1977. To honor papers published at least 30 years that have had a long-lasting impact on the field, the Editors now recognize "Legacy Papers." The journal is pleased to present the following paper as this year's Legacy Paper: "A New Simplified Bioheat Equation for the Effect of Blood Flow on Local Average Tissue Temperature" by S. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042897DOI Listing
February 2019

Waveform Dependent Electrosurgical Effects on Soft Hydrated Tissues.

J Biomech Eng 2019 Feb 19. Epub 2019 Feb 19.

Center for Modeling, Simulation and Imaging in Medicine, Rensselaer Polytechnic Institute, Troy, NY, USA.

Electrosurgical procedures are ubiquitously used in surgery. The commonly used power modes, including the coagulation and blend modes, utilize non-sinusoidal or modulated current waveforms. For the same power setting, the coagulation, blend and pure cutting modes have different heating and thermal damage outcomes due to the frequency dependence of electrical conductivity of soft hydrated tissues. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042898DOI Listing
February 2019

Estimation of the Balance-Keeping Control Law Applied by a Human Being Upon a Sudden Sagittal Tilt Perturbation.

J Biomech Eng 2019 Apr;141(4)

Mechanical Engineering Department, Middle East Technical University, Ankara 06800, Turkey e-mail: .

This study aims to estimate the control law employed by the central nervous system (CNS) to keep a person in balance after a sudden disturbance. For this aim, several experiments were carried out, in which the subjects were perturbed sagittally by using a single-axis tilt-platform and their motions were recorded with appropriate sensors. The analysis of the experimental results leads to the contribution of this paper as a conjecture that the CNS commands the muscular actuators of the joints according to an adaptive proportional-derivative (PD) control law such that its gains and set points are updated continuously. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042683DOI Listing

Assessing Shoulder Biomechanics of Healthy Elderly Individuals During Activities of Daily Living Using Inertial Measurement Units: High Maximum Elevation Is Achievable but Rarely Used.

J Biomech Eng 2019 Apr;141(4)

Thayer School of Engineering, Dartmouth College, Hanover, NH 03755.

Current shoulder clinical range of motion (ROM) assessments (e.g., goniometric ROM) may not adequately represent shoulder function beyond controlled clinical settings. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042433DOI Listing
April 2019
1 Read

Reduced amount or integrity of arterial elastic fibers alters allometric scaling exponents for aortic diameter, but not cardiac function in maturing mice.

J Biomech Eng 2019 Feb 7. Epub 2019 Feb 7.

Department of Mechanical Engineering and Materials Science, Washington University in St. Louis, St. Louis, MO.

Allometric scaling laws relate physiologic parameters to body weight. Genetically modified mice allow investigation of allometric scaling laws when fundamental cardiovascular components are altered. Elastin haploinsufficient (Eln+/-) mice have reduced elastin amounts and fibulin-5 knockout (Fbln5-/-) mice have compromised elastic fiber integrity in the large arteries which may alter cardiovascular scaling laws. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042766DOI Listing
February 2019

Computational Modeling and Analysis of Murmurs Generated by Modeled Aortic Stenoses.

J Biomech Eng 2019 Feb 7. Epub 2019 Feb 7.

Professor, Department of Mechanical Engineering, Johns Hopkins University, 3400 N. Charles Street, Baltimore, MD 21218, USA.

In this study, coupled hemodynamic-acoustic simulations are employed to study the generation and propagation of murmurs associated with aortic stenoses where the aorta with a stenosed aortic valve is modeled as a curved pipe with a constriction near the inlet. The hemodynamics of the post-stenotic flow is investigated in detail in our previous numerical study. The temporal history of the pressure on the aortic lumen is recorded during the hemodynamic study and used as the murmur source in the acoustic simulations. Read More

View Article

Download full-text PDF

Source
http://biomechanical.asmedigitalcollection.asme.org/article.
Publisher Site
http://dx.doi.org/10.1115/1.4042765DOI Listing
February 2019
4 Reads

Kinematic Accuracy in Tracking Total Wrist Arthroplasty with Biplane Videoradiography using a CT-generated Model.

J Biomech Eng 2019 Feb 7. Epub 2019 Feb 7.

Department of Biomedical Engineering, Brown University, Providence, RI 02912; Department of Orthopedics, Alpert Medical School of Brown University and Rhode Island Hospital, Providence, RI 02912.

Total Wrist Arthroplasty (TWA) for improving the functionality of severe wrist joint pathology has not had the same success, in parameters such as motion restoration and implant survival, as hip, knee, and shoulder arthroplasty. These other arthroplasties have been studied extensively, including the use of biplane videoradiography (BVR) that has allowed investigators to study the in-vivo motion of the total joint replacement during dynamic activities. The wrist has not been a previous focus, and utilization of BVR for wrist arthroplasty presents unique challenges due to the design characteristics of TWAs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042769DOI Listing
February 2019
1 Read

Computational and experimental fatigue analysis of contoured spinal rods.

J Biomech Eng 2019 Feb 7. Epub 2019 Feb 7.

Laboratory of Biological Structure Mechanics, Department of Chemistry, Materials and Chemical Engineering "Giulio Natta", Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milan, Italy.

Posterior fixation with contoured rods is an estabilished methodology for the treatment of spinal deformities. Both uniform industrial preforming and intraoperative contouring introduce tensile and compressive plastic deformations, respectively, at the concave and at the convex sides of the rod. The purpose of this study is to develop a validated numerical framework capable of predicting how the fatigue behavior of contoured spinal rods is affected by residual stresses when loaded in lordotic and kyphotic configurations. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042767DOI Listing
February 2019

Structural and Biomechanical Adaptations of Right Ventricular Remodeling - in Pulmonary Arterial Hypertension - Reduces Left Ventricular Rotation During Contraction: A Computational Study.

J Biomech Eng 2019 Feb 4. Epub 2019 Feb 4.

University of Colorado Anschutz Medical Campus, Children's Hospital Colorado.

Pulmonary hypertension (PH) is a degenerative disease characterized by progressively increased right ventricular (RV) afterload that leads to ultimate functional decline [1]. Recent observational studies have documented a decrease in left ventricular (LV) torsion during ejection, with preserved LV ejection fraction (EF) in pediatric and adult PH patients [2-4]. The objective of this study was to develop a computational model of the bi-ventricular heart and use it to evaluate changes in LV torsion mechanics in response to mechanical, structural, and hemodynamic changes in the RV free-wall. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042682DOI Listing
February 2019
1 Read

Model-based analysis of the stiffness of the wrist joint in active and passive conditions.

J Biomech Eng 2019 Feb 4. Epub 2019 Feb 4.

Human Robotics Laboratory, Department of Biomedical Engineering, University of Delaware, Newark, Delaware 19713.

The control of joint stiffness is a fundamental mechanism used to control human movements. While many studies have observed how stiffness is modulated for tasks involving shoulder and elbow motion, a limited amount of knowledge is available for wrist movements, though the wrist plays a crucial role in manipulation. We have developed a computational framework based on a realistic musculoskeletal model, which al to calculate the passive and active components of the wrist joint stiffness. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042684DOI Listing
February 2019
1 Read

Erratum: The mechanical role of the radial fibers network within the annulus fibrosus of the lumbar intervertebral disc: a finite elements study.

J Biomech Eng 2019 Feb 4. Epub 2019 Feb 4.

School of Mechanical Engineering, The Fleischman Faculty of Engineering, Tel Aviv University, Tel Aviv 69978, Israel.

The annulus fibrosus (AF) of the intervertebral disc (IVD) consists of a set of concentric layers composed of a primary circumferential collagen fibers arranged in an alternating oblique orientation. Moreover, there exists an additional secondary set of radial translamellar collagen fibers which connects the concentric layers, creating an entangled fiber network. The aim of this study is to investigate the mechanical role of the radial fiber network. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042685DOI Listing
February 2019

Balance-Keeping Control of a Human Being Upon a Sudden External Perturbation.

J Biomech Eng 2019 Feb 4. Epub 2019 Feb 4.

Mechanical Engineering Department, Middle East Technical University, Ankara, Turkey.

This study aims to estimate the control law employed by the CNS (Central Nervous System) to keep a person in balance after a sudden disturbance. For this aim, several experiments were carried out, in which the subjects were perturbed sagittally by using a single-axis tilt-platform and their motions were recorded with appropriate sensors. The analysis of the experimental results leads to the conjecture that the CNS commands the muscular actuators of the human joints according to a PD control law but it updates the control gains and the set points continuously. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042683DOI Listing
February 2019

Accurate and Efficient Plate and Rod Micro Finite Element Whole Bone Models Based on High-Resolution Peripheral Computed Tomography.

J Biomech Eng 2019 Jan 31. Epub 2019 Jan 31.

Bone Bioengineering Laboratory, Department of Biomedical Engineering, Columbia University, New York, New York, U.S.A.

The high-resolution peripheral quantitative computed tomography (HRpQCT) provides unprecedented visualization of bone microstructure and the basis for constructing patient-specific micro-finite element (µFE) models. Based on HRpQCT images, we have developed a plate rod µFE (PRµFE) method for whole bone segments using individual trabecula segmentation (ITS) and an adaptive cortical meshing technique. In contrast to the conventional voxel approach, the complex microarchitecture of the trabecular compartment is simplified into shell and beam elements based on the trabecular plate-and-rod configuration. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042680DOI Listing
January 2019

Effect of Local Neck Anatomy on Localized One-Dimensional Measurements of Arterial Stiffness: A Finite-Element Model Study.

J Biomech Eng 2019 Mar;141(3)

Ultrasound Elasticity Imaging Laboratory, Columbia University, Columbia University Medical Campus, 630 West 168th Street, Physicians & Surgeons 19-418, New York, NY 10032 e-mail: .

Cardiovascular diseases (CVD) are the most prevalent cause of death in the Western World, and their prevalence is only expected to rise. Several screening modalities aim at detecting CVD at the early stages. A common target for early screening is common carotid artery (CCA) stiffness, as reflected in the pulse wave velocity (PWV). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042435DOI Listing

A Hybrid Experimental-Computational Modeling Framework For Cardiovascular Device Testing.

J Biomech Eng 2019 Jan 30. Epub 2019 Jan 30.

Dept. of Mechanical Engineering, Clemson University, SC, USA., Fluor Daniel Building, Clemson University, Clemson, SC 29634-0921, Ph: (864) 656-2482.

Significant advances in biomedical science often leverage powerful computational and experimental modeling platforms. We present a framework named "PSCOPE" that can capitalize the strengths of both types of platforms in a hybrid model. PSCOPE uses an iterative method to couple an in-vitro mock circuit to a lumped-parameter numerical simulation of physiology, obtaining closed-loop feedback between the two. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042665DOI Listing
January 2019

Mapping of Intervertebral Disc Annulus Fibrosus Compressive Properties is Sensitive to Specimen Boundary Conditions.

J Biomech Eng 2019 Jan 23. Epub 2019 Jan 23.

Department of Mechanical & Aeronautical Engineering, Clarkson University, Box 5725, Potsdam, NY, 13699.

Predicting the mechanical behavior of the intervertebral disc (IVD) in health and in disease requires accurate spatial mapping of its compressive mechanical properties. Previous studies confirmed that residual strains in the annulus fibrosus (AF) of the IVD, which result from non-uniform extracellular matrix deposition in response to in-vivo loads, vary by anatomical region (anterior, posterior, and lateral) and zone (inner, middle, and outer). We hypothesized that as the AF is composed of a nonlinear, anisotropic, viscoelastic material, the state of residual strain in the transverse plane would influence the apparent values of axial compressive properties. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042600DOI Listing
January 2019

Quantification of Morphological Modulation, F-Actin Remodeling and PECAM-1 (CD-31) Re-distribution in Endothelial Cells in Response to Fluid-Induced Shear Stress under Various Flow Conditions.

J Biomech Eng 2019 Jan 23. Epub 2019 Jan 23.

Advanced Fluid Mechanics Research Group, Department of Mechanical and Materials Engineering, University of Western Ontario, London, Ontario, Canada, N6A 3K7.

Cardiovascular diseases (CVDs) are the number one cause of death globally. Arterial endothelial cell (EC) dysfunction plays a key role in many of these CVDs, such as atherosclerosis. Blood flow-induced wall shear stress (WSS), among many other pathophysiological factors, is known to significantly contribute to EC dysfunction. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042601DOI Listing
January 2019

The Effect of Inhomogeneous Trabecular Stiffness Relationship Selection on Finite Element Outcomes for Shoulder Arthroplasty.

J Biomech Eng 2019 Mar;141(3)

Department of Mechanical Engineering, Western University Canada, 1151 Richmond Street, London, ON N6A3K7, Canada e-mail: .

An important feature of humeral orthopedic finite element (FE) models is the trabecular stiffness relationship. These relationships depend on the anatomic site from which they are derived; but have not been developed for the humerus. As a consequence, humeral FE modeling relies on relationships for other anatomic sites. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042172DOI Listing
March 2019
1 Read

Monte Carlo type Simulations of Mineralized Collagen Fibril based on Two Scale Asymptotic Homogenization.

J Biomech Eng 2019 Jan 7. Epub 2019 Jan 7.

Assistant Professor, School of Engineering, Indian Institute of Technology Mandi, Kamand - 175005, Mandi, Himachal Pradesh, India.

A multi-scale model for mineralized collagen fibril is proposed by taking into account the uncertainties associated with the geometrical properties of mineral phase and its distribution in the organic matrix. The asymptotic homogenization approach along with periodic boundary conditions has been used to derive the effective elastic moduli at two hierarchical length scales, namely: microfibril and mineralized collagen fibril. The uncertainties associated with the mineral plates have been directly included in the finite element mesh by randomly varying their sizes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042439DOI Listing
January 2019
1 Read

Swine Vagina under Planar Biaxial Loads: An Investigation of Large Deformations and Tears.

J Biomech Eng 2019 Jan 7. Epub 2019 Jan 7.

STRETCH Lab, Department of Biomedical Engineering and Mechanics, Virginia Tech, Blacksburg, Virginia, 24061.

Vaginal tears are very common and can lead to hemorrhaging, fecal incontinence, urinary incontinence, and dyspareunia. Despite the complication of vaginal tears on women's health, there are no studies on the tear behavior of vaginal tissue. In this study, planar equi-biaxial tests on square specimens of swine vaginal tissue, with sides oriented along the longitudinal direction (LD) and circumferential direction (CD), were conducted. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042437DOI Listing
January 2019
1 Read

Assessing Upper Extremity Biomechanics during Activities of Daily Living Using Inertial Measurement Units: Does our Concept of 'Normal' Apply?

J Biomech Eng 2019 Jan 7. Epub 2019 Jan 7.

Dartmouth College, Thayer School of Engineering.

Current shoulder clinical range of motion (ROM) assessments (e.g. goniometric ROM) may not adequately represent shoulder function beyond clinical settings. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042433DOI Listing
January 2019

The path to deliver the most realistic follower load for a lumbar spine in standing posture: A finite element study.

J Biomech Eng 2019 Jan 7. Epub 2019 Jan 7.

Shanghai Institute of Applied Mathematics and Mechanics, Shanghai University, Shanghai 200072, China.

A spine is proven to be subjected to a follower load which is a compressive load of physiologic magnitude acting on the whole spine. The path of the follower load approximates the tangent to the curve of the spine in in vivo neutral standing posture. However, the specific path location of the follower load is still unclear. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042438DOI Listing
January 2019
5 Reads

Effect of local Neck Anatomy on Localized 1D-Measurements of Arterial Stiffness: a FEM Study.

J Biomech Eng 2019 Jan 7. Epub 2019 Jan 7.

Ultrasound Elasticity Imaging Laboratory, Columbia University, New York, USA, Columbia University Medical Campus, 630 West 168th Street, Physicians & Surgeons 19-418, New York, NY, USA 10032.

Cardiovascular diseases (CVD) are the most prevalent cause of death in the Western World, and their prevalence is only expected to rise. Several screening modalities aim at detecting CVD at the early stages. A common target for early screening is common carotid artery (CCA) stiffness, as reflected in the pulse wave velocity (PWV). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042435DOI Listing
January 2019

An Efficient Inverse Dynamics Optimization Formulation for Musculoskeletal Motion Prediction.

Authors:
Yujiang Xiang

J Biomech Eng 2019 Jan 7. Epub 2019 Jan 7.

School of Mechanical and Aerospace Engineering, Oklahoma State University, Stillwater, OK 74078 USA.

In this study, an inverse dynamics optimization formulation and solution procedure is developed for musculoskeletal simulations. The proposed method has three main features: high order recursive B-spline interpolation, partition of unity, and inverse dynamics formulation. First, joint angle and muscle force profiles are represented by recursive B-splines. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042436DOI Listing
January 2019

THE EFFECTS OF BONE MICROSTRUCTURE ON SUBSIDENCE RISK FOR ALIF, LLIF, PLIF, AND TLIF SPINE CAGES.

J Biomech Eng 2018 Dec 5. Epub 2018 Dec 5.

U.S. Food and Drug Administration, Center for Devices and Radiological Health, Office of Science and Engineering Laboratories, Division of Applied Mechanics, Silver Spring, Maryland, 20993 USA.

Several approaches (anterior, posterior, lateral, and transforaminal) are used in lumbar fusion surgery. However, it is unclear whether one of these approaches has the greatest subsidence risk as published clinical rates of cage subsidence vary widely (7-70%). Specifically, there is limited data on how a patient's endplate morphometry and trabecular bone quality influences cage subsidence risk. Read More

View Article

Download full-text PDF

Source
http://biomechanical.asmedigitalcollection.asme.org/article.
Publisher Site
http://dx.doi.org/10.1115/1.4042181DOI Listing
December 2018
13 Reads

Design of a Novel Electrode of Radiofrequency Ablation for Large Tumors: In Vitro Validation and Evaluation.

J Biomech Eng 2018 Dec 5. Epub 2018 Dec 5.

Mem. ASME, Tumor Ablation Group, Biomedical Science and Technology Research Center, School of Mechatronic Engineering and Automation, Shanghai University, Shanghai 200444, China.

In the present study, a monopolar expandable electrode (MEE) in radiofrequency ablation (RFA) proposed in our previous study was validated and evaluated using the in vitro experiment and computer simulation. Two commercial RF electrodes (conventional electrode, CE and umbrella electrode, UE) was used to compare the ablation results with MEE using the in vitro egg white model (experiment and computer simulation) and in vivo liver tumor model (computer simulation) to verify the efficacy of MEE in the large tumor ablation. The sharp increase in impedance during RFA procedures was taken as the termination of RFA protocols. Read More

View Article

Download full-text PDF

Source
http://biomechanical.asmedigitalcollection.asme.org/article.
Publisher Site
http://dx.doi.org/10.1115/1.4042179DOI Listing
December 2018
12 Reads

A synergy-based motor control framework for the fast feedback control of musculoskeletal systems.

J Biomech Eng 2018 Dec 5. Epub 2018 Dec 5.

Professor, Fellow of ASME, Systems Design Engineering, University of Waterloo, Waterloo, Canada N2L 3G1.

This paper presents a computational framework for the fast feedback control of musculoskeletal systems using muscle synergies. The proposed motor control framework has a hierarchical structure. A feedback controller at the higher level of hierarchy handles the trajectory planning and error compensation in the task space. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042185DOI Listing
December 2018
2 Reads

Considerations for translation of tissue engineered fibrocartilage from bench to bedside.

J Biomech Eng 2018 Dec 5. Epub 2018 Dec 5.

ASME Fellow, Distinguished Professor, Department of Biomedical Engineering, University of California, Irvine, Irvine, CA 92697.

Fibrocartilage is found in the knee meniscus, the temporomandibular joint (TMJ) disc, the pubic symphysis, the annulus fibrosus of intervertebral disc, tendons, and ligaments. These tissues are notoriously difficult to repair due to their avascularity, and limited clinical repair and replacement options exist. Tissue engineering has been proposed as a route to repair and replace fibrocartilages. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042201DOI Listing
December 2018
1 Read

Validation of an in vivo Medical Image-Based Young Human Lumbar Spine Finite Element Model.

J Biomech Eng 2018 Dec 5. Epub 2018 Dec 5.

ASME Fellow, Mechanical and Aerospace Engineering Department, Biomedical Engineering Department, University of California, Davis, 2132 Bainer Drive, Davis, CA 95616-5294.

Mathematical models of the human spine can be used to investigate spinal biomechanics without the difficulties, limitations and ethical concerns associated with physical experimentation. Validation of such models is necessary to ensure the modeled system behavior accurately represents the physics of the actual system. The goal of this work was to validate a medical image-based nonlinear lumbosacral spine finite element model of a healthy 20-year-old female subject under physiological moments. Read More

View Article

Download full-text PDF

Source
http://biomechanical.asmedigitalcollection.asme.org/article.
Publisher Site
http://dx.doi.org/10.1115/1.4042183DOI Listing
December 2018
9 Reads

Elastic fiber fragmentation increases transmural hydraulic conductance and solute transport in mouse arteries.

J Biomech Eng 2018 Dec 5. Epub 2018 Dec 5.

Department of Mechanical Engineering and Materials Science, Washington University, One Brookings Dr., CB 1185, St. Louis, MO 63130.

Transmural advective transport of solute and fluid was investigated in mouse carotid arteries with either a genetic knockout of Fibulin-5 (Fbln5-/-) or treatment with elastase to determine the influence of a disrupted elastic fiber matrix on wall transport properties. Fibulin-5 is an important director of elastic fiber assembly. Arteries from Fbln5-/- mice have a loose, non-continuous elastic fiber network and were hypothesized to have reduced resistance to advective transport. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042173DOI Listing
December 2018
1 Read

Dynamic Balance during Human Movement: Measurement and Control Mechanisms.

J Biomech Eng 2018 Dec 5. Epub 2018 Dec 5.

Motion Analysis Center, Brooks Rehabilitation, Jacksonville, FL, USA.

Walking can be exceedingly complex to analyze due to highly nonlinear multi-body dynamics, nonlinear relationships between muscle excitations and resulting muscle forces, dynamic coupling that allows muscles to accelerate joints and segments they do not span, and redundant muscle control. Walking requires the successful execution of a number of biomechanical functions such as providing body support, forward propulsion and balance control, with specific muscle groups contributing to their execution. Thus, muscle injury or neurological impairment that affects muscle output can alter the successful execution of these functions and impair walking performance. Read More

View Article

Download full-text PDF

Source
http://biomechanical.asmedigitalcollection.asme.org/article.
Publisher Site
http://dx.doi.org/10.1115/1.4042170DOI Listing
December 2018
9 Reads

Reduced order models for transstenotic pressure drop in the coronary arteries.

J Biomech Eng 2018 Dec 5. Epub 2018 Dec 5.

Mechanical Engineering, University of California Berkeley, CA, 94720.

The efficacy of reduced order modeling for transstenotic pressure drop in the coronary arteries is presented. Coronary artery disease is a leading cause of death worldwide and the computation of fractional flow reserve from computed tomography (FFRct) has become a standard for evaluating the functional significance of a coronary stenosis. FFRct uses 3D computational fluid dynamics to simulate coronary blood flow in order to compute transstenotic pressure drop during simulated hyperemia. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042184DOI Listing
December 2018

The Effect of Trabecular Modulus Anatomic Site Selection on FE Outcomes for Shoulder Arthroplasty.

J Biomech Eng 2018 Dec 5. Epub 2018 Dec 5.

Department of Mechanical Engineering, Western University Canada, 1151 Richmond Street, London, Ontario, N6A3K7, Canada.

An important feature of humeral orthopaedic Finite Element (FE) models is the trabecular stiffness relationship. These relationships depend on the anatomic site from which they are derived; but have not been developed for the humerus. As a consequence, humeral FE modeling relies on relationships for other anatomic sites. Read More

View Article

Download full-text PDF

Source
http://biomechanical.asmedigitalcollection.asme.org/article.
Publisher Site
http://dx.doi.org/10.1115/1.4042172DOI Listing
December 2018
7 Reads

Fundamental Roles of Axial Stretch in Isometric and Isobaric Evaluations of Vascular Contractility.

J Biomech Eng 2019 Mar;141(3)

Department of Biomedical Engineering, Yale University, 55 Prospect Street, New Haven, CT 06520 e-mail: .

Vascular smooth muscle cells (VSMCs) can regulate arterial mechanics via contractile activity in response to changing mechanical and chemical signals. Contractility is traditionally evaluated via uniaxial isometric testing of isolated rings despite the in vivo environment being very different. Most blood vessels maintain a locally preferred value of in vivo axial stretch while subjected to changes in distending pressure, but both of these phenomena are obscured in uniaxial isometric testing. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042171DOI Listing
March 2019
1 Read

Constrained Dynamic Optimization of Sit-to-Stand Motion Driven by Bézier Curves.

J Biomech Eng 2018 Dec;140(12)

ASME Fellow Systems Design Engineering, University of Waterloo, , Waterloo, ON N2 L 3G1, Canada e-mail: .

The purpose of this work is twofold: first, to synthesize a motion pattern imitating sit-to-stand (STS) and second, to compare the kinematics and dynamics of the resulting motion to healthy STS. Predicting STS in simulation inspired the creation of three models: a biomechanical model, a motion model, and performance criteria as a model of preference. First, the human is represented as three rigid links in the sagittal plane. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4041527DOI Listing
December 2018

The Effect of Textiles Impregnated with Particles of High Emissivity in the Far Infrared, on the Temperature of the Cold Hand.

J Biomech Eng 2018 Nov 20. Epub 2018 Nov 20.

Fellow ASME, Department of Mechanical Engineering, University of California Berkeley, Berkeley CA 94720 USA.

In engineering and medicine, there is a growing interest in using textiles made of composites with enhanced thermal properties. One such type of textile is fabric impregnated with ceramics and mineral particles. This material has high emissivity in the infrared range and may have therapeutic benefits for treatments of diseases, like Raynaud's syndrome. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042044DOI Listing
November 2018
1 Read

Numerical Simulation of the Heat Transfer in the Cryoprobe of an Innovative Apparatus for Cryosurgery.

J Biomech Eng 2019 Jan;141(1)

Department of Civil, Chemical and Environmental Engineering, University of Genoa, Via Opera Pia 15, Genova 16145, Italy e-mail: .

Cryosurgery is a rapidly developing discipline, alternative to conventional surgical techniques, used to destroy cancer cells by the action of low temperatures. Currently, the refrigeration is obtained via the adiabatic expansion of gases in probes used for surgeries, with the need of inherently dangerous pressurized vessels. The proposed innovative prototypal apparatus aims to reach the cryosurgical temperatures exploiting a closed-loop refrigeration system, avoiding the hazardous presence of pressurized vessels in the operating room. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4041526DOI Listing
January 2019

A Data-Driven Personalized Model of Glucose Dynamics Taking Account of the Effects of Physical Activity for Type 1 Diabetes: An In Silico Study.

Authors:
Jinyu Xie Qian Wang

J Biomech Eng 2019 Jan;141(1)

Mem. ASME Professor Mechanical Engineering, 325 Leonhard Building, Penn State University, University Park, PA 16802 e-mail: .

This paper aims to develop a data-driven model for glucose dynamics taking into account the effects of physical activity (PA) through a numerical study. It intends to investigate PA's immediate effect on insulin-independent glucose variation and PA's prolonged effect on insulin sensitivity. We proposed a nonlinear model with PA (NLPA), consisting of a linear regression of PA and a bilinear regression of insulin and PA. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4041522DOI Listing
January 2019
6 Reads
1.780 Impact Factor

Characterizing the Biomechanical Properties of the Pubovisceralis Muscle Using a Genetic Algorithm and the Finite Element Method.

J Biomech Eng 2019 Jan;141(1)

LAETA, INEGI, Faculty of Engineering, University of Porto, Rua Roberto Frias s/n, Porto 4200-465, Portugal e-mail: .

To better understand the disorders in the pelvic cavity associated with the pelvic floor muscles (PFM) using computational models, it is fundamental to identify the biomechanical properties of these muscles. For this purpose, we implemented an optimization scheme, involving a genetic algorithm (GA) and an inverse finite element analysis (FEA), in order to estimate the material properties of the pubovisceralis muscle (PVM). The datasets of five women were included in this noninvasive analysis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4041524DOI Listing
January 2019
1 Read

Mesh sensitivity analysis for quantitative shear stress assessment in blood pumps using computational fluid dynamics.

J Biomech Eng 2018 Nov 20. Epub 2018 Nov 20.

Department of Cardiovascular Engineering, Institute of Applied Medical Engineering, Helmholtz Institute, RWTH Aachen University, Aachen, Germany; Enmodes GmbH, 52074 Aachen, Germany.

The reduction of excessive, nonphysiologic shear stresses leading to blood trauma can be the key to overcome many of the associated complications in blood recirculating devices. In that regard, Computational Fluid Dynamics (CFD) are gaining in importance for the hydraulic and hemocompatibility assessment. Still, direct hemolysis assessments with CFD remain inaccurate and limited to qualitative comparisons rather than quantitative predictions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042043DOI Listing
November 2018
17 Reads
1.780 Impact Factor

An Injury Risk Function for the Leg, Foot, and Ankle Exposed to Axial Impact Loading Using Force and Impulse.

J Biomech Eng 2019 Feb;141(2)

Center for Applied Biomechanics, University of Virginia, , Charlottesville, VA 22911 e-mail: .

Most injury risk functions (IRFs) for dynamic axial loading of the leg have been targeted toward automotive applications such as predicting injury caused by intrusion into the occupant compartment from frontal collisions. Recent focus on leg injuries in the military has led to questions about the applicability of these IRFs shorter duration, higher amplitude loading associated with underbody blast (UBB). To investigate these questions, data were collected from seven separate test series that subjected post-mortem human legs to axial impact. Read More

View Article

Download full-text PDF

Source
http://biomechanical.asmedigitalcollection.asme.org/article.
Publisher Site
http://dx.doi.org/10.1115/1.4042012DOI Listing
February 2019
17 Reads

IMPACT OF CALCIUM QUANTIFICATIONS ON STENT EXPANSIONS.

J Biomech Eng 2018 Nov 15. Epub 2018 Nov 15.

Department of Mechanical & Materials Engineering, University of Nebraska-Lincoln, Lincoln, NE 68588-0656.

Severely calcified plaque is of great concern when planning and implementing a stenting intervention. In this work, computational models were developed to investigate the influence of calcium characteristics on stenting outcomes. The commonly used clinical measurements of calcium (i. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298533PMC
November 2018

Effects of elastase digestion on the murine vaginal wall biaxial mechanical response.

J Biomech Eng 2018 Nov 15. Epub 2018 Nov 15.

ASME Member, Department of Biomedical Engineering, Lindy Boggs Center Suite 500, Tulane University, New Orleans, LA 70118 USA.

Although the underlying mechanisms of pelvic organ prolapse (POP) remain unknown, disruption of elastic fiber metabolism within the vaginal wall extracellular matrix has been highly implicated. It has been hypothesized that elastic fiber fragmentation correlates to decreased structural integrity and increased risk of prolapse; however, the mechanisms by which elastic fiber damage may contribute to prolapse are poorly understood. Further, the role of elastic fibers in normal vaginal wall mechanics has not been fully ascertained. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4042014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298538PMC
November 2018
9 Reads

Comparison of Biomechanical Properties and Microstructure of Trabeculae Carneae, Papillary muscles, and Myocardium in Human Heart.

J Biomech Eng 2018 Nov 10. Epub 2018 Nov 10.

Department of Mechanical Engineering, University of Texas at San Antonio, USA.

Trabeculae carneae account for a significant portion of human ventricular mass, despite being considered embryologic remnants. Recent studies have found trabeculae hypertrophy and fibrosis in hypertrophied left ventricles with various pathological conditions. The objective of this study was to investigate the passive mechanical properties and microstructural characteristics of trabeculae carneae and papillary muscles compared to the myocardium in human hearts. Read More

View Article

Download full-text PDF

Source
http://biomechanical.asmedigitalcollection.asme.org/article.
Publisher Site
http://dx.doi.org/10.1115/1.4041966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298537PMC
November 2018
1 Read