10,514 results match your criteria Journal of affective disorders[Journal]


Neuroticism and chronicity as predictors of 9-year course of individual depressive symptoms.

J Affect Disord 2019 Apr 15;252:484-492. Epub 2019 Apr 15.

Department of Psychiatry, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, the Netherlands.

Background: The large between-person differences in symptomatology suggest that major depressive disorder (MDD) is a heterogeneous psychiatric disorder. However, symptom-specific prospective studies are scarce. We hypothesized that chronicity (i. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.052DOI Listing

Pilot trial of home-administered transcranial direct current stimulation for the treatment of depression.

J Affect Disord 2019 Apr 10;252:475-483. Epub 2019 Apr 10.

School of Psychiatry, University of New South Wales/Black Dog Institute, Hospital Road, Randwick, NSW 2031, Australia; St George Hospital, South Eastern Sydney Health, Level 2, James Laws House, Gray St, Kogarah, NSW 2217, Australia.

Background: Transcranial Direct Current Stimulation (tDCS) is a non-invasive, neuromodulation approach with promising efficacy for treating depression. To date, tDCS has been limited to clinical or research centre settings with treatment administered by staff. The aim of this study is to examine the efficacy, tolerability and feasibility of home-administered, remotely-supervised tDCS for depression. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.041DOI Listing

Temperament and character influence on depression treatment outcome.

J Affect Disord 2019 Apr 9;252:464-474. Epub 2019 Apr 9.

Department of Biomedical and NeuroMotor Sciences, University of Bologna, Italy. Electronic address:

Background: personality features have been repeatedly associated with depression treatment outcome in Major Depressive Disorder (MDD), however conclusive results are still lacking. Moreover, as for Bipolar Disorder (BD), results are only few and preliminary.

Aim: the aim of the present study was to perform an exploratory investigation of the influence of personality traits as assessed by the Temperament and Character Inventory (TCI), on principal depression treatment outcomes (non remission, non response and resistance). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01650327183178
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http://dx.doi.org/10.1016/j.jad.2019.04.031DOI Listing
April 2019
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Social support from friends and depression among African Americans: The moderating influence of education.

J Affect Disord 2019 Apr 8;253:1-7. Epub 2019 Apr 8.

Center for the Study of Aging and Human Development, Duke University, Durham, NC 27710.

Background: This cross-sectional study examined the association between various characteristics of friendships and 12-month major depressive disorder (MDD) and whether these associations vary by education level among African Americans.

Methods: The analytic sample included 3434 African American respondents drawn from the National Survey of American Life: Coping with Stress in the 21st Century. Logistic regression analyses were performed to test the associations between friendship characteristics (i. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01650327183301
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http://dx.doi.org/10.1016/j.jad.2019.04.013DOI Listing
April 2019
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Obstetric complications in bipolar disorder: The role of mental health disorders in the risk of caesarean section.

J Affect Disord 2019 Apr 8;252:458-463. Epub 2019 Apr 8.

Perinatal Mental health Unit, Department of Psychiatry and Clinical Psychology, Institute of Neuroscience, Hospital Clinic, IDIBAPS, Barcelona, Catalonia, Spain; Vulnerability, Psychopathology and Gender research group, Generalitat de Catalunya, Catalonia, Spain.

Background: Women with Bipolar Disorder (BD) during pregnancy present a negative impact on them and their babies' health. Caesarean Section (C-Section) is an intervention to reduce complications associated with childbirth, but it also has risks, including maternal infections, anaesthetic and psychological complications. There are few studies that analyse the C-Section rates in women with BD compared to the general population. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01650327183226
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http://dx.doi.org/10.1016/j.jad.2019.04.017DOI Listing
April 2019
2 Reads

Psychotropic polypharmacy reconsidered: Between-class polypharmacy in the context of multimorbidity in the treatment of depressive disorders.

J Affect Disord 2019 Apr 8;252:450-457. Epub 2019 Apr 8.

Department of Psychiatry, School of Medicine, Yale University, New Haven, CT, United States; Veterans Affairs (VA) New England Mental Illness Research, Education and Clinical Centers (MIRECC), West Haven, CT, United States; Veterans Affairs (VA) Connecticut Healthcare System, West Haven, CT, United States.

Objectives: Both psychiatric polypharmacy and multimorbidity are common in depressed adults. We examine recent patterns of psychotropic polypharmacy with attention to concurrent multimorbidity in the treatment of depressive disorders in outpatient psychiatric care.

Methods: Data from the 2006-2015 National Ambulatory Medical Care Survey offer nationally representative samples of office-based psychiatric care in adults with depressive disorders (ICD-9-CM codes 296. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.018DOI Listing

Evaluation of a guided internet-based self-help intervention for older adults after spousal bereavement or separation/divorce: A randomised controlled trial.

J Affect Disord 2019 Apr 8;252:440-449. Epub 2019 Apr 8.

University of Bern, Department of Psychology, Fabrikstrasse 8, 3012 Bern, Switzerland. Electronic address:

Background: While several internet interventions target severe prolonged grief symptoms after bereavement, no randomised controlled trial investigated interventions for prolonged grief after separation/divorce.

Methods: This randomised controlled trial aimed to evaluate the efficacy of a guided internet-based self-help intervention for prolonged grief symptoms after spousal bereavement or separation/divorce compared to a wait-list control group. Furthermore, we analysed whether the intervention was also efficacious for participants with milder grief symptoms. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.008DOI Listing

Efficacy of repetitive transcranial magnetic stimulation in the treatment of depression with comorbid anxiety disorders.

J Affect Disord 2019 Mar 30;252:435-439. Epub 2019 Mar 30.

The Adelaide Clinic, Ramsay Health Care (SA) Mental Health Services, South Australia, Australia; Discipline of Psychiatry, School of Medicine, The University of Adelaide, South Australia, Australia; Northern Adelaide Local Health Network, South Australia, Australia. Electronic address:

Background: The presence of comorbid anxiety is generally associated with poorer treatment outcomes in people with depression. Repetitive transcranial magnetic stimulation (rTMS) has been shown to be effective for treatment resistant depression, but there has been little research examining rTMS in depressed patients with comorbid anxiety disorders. This study aimed to investigate the efficacy of rTMS in patients with treatment resistant Major Depressive Disorder (MDD) and comorbid anxiety disorders. Read More

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http://dx.doi.org/10.1016/j.jad.2019.03.085DOI Listing

Trajectories of PTSD symptoms among children who survived the Lushan earthquake: A four-year longitudinal study.

J Affect Disord 2019 Apr 9;252:421-427. Epub 2019 Apr 9.

CAS Key Laboratory of Mental Health, Institute of Psychology, 16 Lincui Road, Chaoyang District, Beijing 100101, China. Electronic address:

Background: This study aimed to explore the trajectories of posttraumatic stress disorder (PTSD) symptoms among child survivors of the Lushan earthquake by using latent category growth analysis.

Methods: In total, 304 students from a school located in Lushan County were assessed by UCLA PTSD-RI at 1.5, 6, 12, 24 and 48 months after the earthquake. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.047DOI Listing
April 2019
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Heritability estimates of individual psychological distress symptoms from genetic variation.

J Affect Disord 2019 Apr 8;252:413-420. Epub 2019 Apr 8.

Samsung Advanced Institute for Health Sciences and Technology (SAIHST), Sungkyunkwan University, Samsung Medical Center, Seoul, South Korea. Electronic address:

Background: Psychological distress symptoms are associated with an increased risk of psychiatric disorders and medical illness. Although psychological distress is influenced by environmental factors, such as socioeconomic status, lifetime events, or interpersonal relationships, substantial interindividual variation also exists. However, heritability and genetic determinants of distress are poorly understood. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.011DOI Listing

Abdominal vagal deafferentation alters affective behaviors in rats.

J Affect Disord 2019 Apr 7;252:404-412. Epub 2019 Apr 7.

Institute of Pharmacology and Toxicology, University of Zurich-Vetsuisse, Zurich, Switzerland; Neuroscience Center Zurich, University of Zurich and ETH Zurich, Switzerland.

Background: There is growing evidence for a role of abnormal gut-brain signaling in disorders involving altered mood and affect, including depression. Studies using vagus nerve stimulation (VNS) suggest that the disruption of vagal afferent signaling may contribute to these abnormalities. To test this hypothesis, we used a rat model of subdiaphragmatic vagal deafferentation (SDA), the most complete and selective vagal deafferentation method existing to date, to study the consequences of complete disconnection of abdominal vagal afferents on affective behaviors. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01650327183197
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http://dx.doi.org/10.1016/j.jad.2019.04.015DOI Listing
April 2019
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Temperament correlates in adult ADHD: A systematic review.

J Affect Disord 2019 Apr 8;252:394-403. Epub 2019 Apr 8.

Department of Neurosciences, Mental Health and Sensory Organs, Suicide Prevention Center, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy. Electronic address:

Background: Attention deficit and hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder in children, but adult-ADHD is still an under-diagnosed and untreated condition. Treating adult-ADHD is complex and requires effective strategies for ADHD symptoms and comorbidities. Because of its high comorbidity rate with mood disorders and the growing interest in symptoms of emotional dysregulation in these patients, our aim was to collect studies that investigated temperament correlates in adult people with ADHD, to better understand the association between them and the eventual role of temperament as a prognostic-therapeutic marker. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01650327183303
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http://dx.doi.org/10.1016/j.jad.2019.04.006DOI Listing
April 2019
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Prevalence and potential determinants of subthreshold and major depression in the general population of Qatar.

Authors:
Salma M Khaled

J Affect Disord 2019 Apr 9;252:382-393. Epub 2019 Apr 9.

Social and Economic Survey Research Institute, Qatar University, Doha, Qatar. Electronic address:

Background: There is a paucity of epidemiological studies of depression in war-free Arab countries. This study estimated the prevalence and potential determinants of Subthreshold (SUBDE) and Major Depressive Episode (MDE) in migrants and non-migrants typical of Qatar and neighboring Gulf countries.

Methods: A telephone survey of a probability-based sample of 2,424 participants was conducted in February 2017. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.056DOI Listing

Role of DNA hypomethylation in lateral habenular nucleus in the development of depressive-like behavior in rats.

J Affect Disord 2019 Mar 22;252:373-381. Epub 2019 Mar 22.

Department of Physiology, College of Basic Medical Sciences, Jilin University, Changchun, Jilin 130021, China. Electronic address:

Background: Lateral habenula nucleus (LHb) has recently been noted for its role in stress-induced depressive disorder. Yet little is known about the mechanisms by which external stimuli or depression induces pathological alteration in the LHb.

Methods: Chronic unpredictable mild stress (CUMS) was employed to model depressive-like behaviors in adult rats. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01650327183242
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http://dx.doi.org/10.1016/j.jad.2019.03.062DOI Listing
March 2019
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Identification of major depressive disorder and prediction of treatment response using functional connectivity between the prefrontal cortices and subgenual anterior cingulate: A real-world study.

J Affect Disord 2019 Apr 8;252:365-372. Epub 2019 Apr 8.

Medical School of Nanjing University, 22 Hankou Road, Nanjing 210093, China; Department of Psychiatry, the Affiliated Brain Hospital of Nanjing Medical University, Nanjing 210029, China. Electronic address:

Background: Major depressive disorder (MDD) is associated with a heavy disease burden due to the difficulty in diagnosing the disorder and the uncertainty of treatment outcomes. Previous studies have demonstrated the value of functional connectivity (FC) between the dorsolateral prefrontal cortex (DLPFC) and the subgenual anterior cingulate cortex (sgACC) in the identification of MDD and the prediction of antidepressant efficacy. In the present study, we aimed to investigate whether FC is helpful in discriminating patients from healthy controls and in predicting treatment outcome. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.046DOI Listing
April 2019
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Saving inventory - Revised: Psychometric performance across the lifespan.

J Affect Disord 2019 Apr 8;252:358-364. Epub 2019 Apr 8.

University of British Columbia, Department of Psychology, 2136 West Mall, Vancouver, BC V6T 1Z4 Canada.

Background: The Saving Inventory - Revised (SI-R) is the most widely used self-report measure of hoarding symptom severity. The goal of this study is to establish a firm empirical basis for a cutoff score on the SI-R and to examine the functioning of the SI-R as a screening tool and indicator of hoarding symptom severity across the lifespan.

Methods: This study used archival data from 1,116 participants diagnosed with a clinical interview in 14 studies conducted by research groups who focus on hoarding. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.007DOI Listing

Post-traumatic stress following military deployment: Genetic associations and cross-disorder genetic correlations.

J Affect Disord 2019 Apr 9;252:350-357. Epub 2019 Apr 9.

Research and Knowledge Center, The Danish Veteran Center, Garnisonen 1, 4100 Ringsted, Denmark.

Background: Post-traumatic stress disorder (PTSD) is a complex psychiatric disorder that occurs with relatively high frequency after deployment to warzones (∼10%). While twin studies have estimated the heritability to be up to 40%, thus indicating a considerable genetic component in the etiology, the biological mechanisms underlying risk and development of PTSD remain unknown.

Methods: Here, we conduct a genome-wide association study (GWAS; N = 2,481) to identify genome regions that associate with PTSD in a highly homogenous, trauma-exposed sample of Danish soldiers deployed to war and conflict zones. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.070DOI Listing
April 2019
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The effect of adjunctive nutraceuticals in bipolar disorder: A systematic review of randomized placebo-controlled trials.

J Affect Disord 2019 Apr 8;252:334-349. Epub 2019 Apr 8.

Department of Clinical and Experimental Medicine, Psychiatry Unit, University of Catania, Italy; U.O.C. Clinica Psichiatrica, A.O.U. Policlinico-Vittorio Emanuele, Presidio "G. Rodolico", Catania, Italy.

Background: Nutraceuticals are a group of compounds of growing interest for mental health professionals. Given the implication of certain nutrients in the onset of bipolar disorder, it has been hypothesized that nutraceuticals might be effective in improving symptoms of the condition (i.e. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.039DOI Listing
April 2019
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What DNA methylation modifications and/or genetic variations interact with childhood maltreatment in the development of depression: A systematic review.

J Affect Disord 2019 Apr 9;252:325-333. Epub 2019 Apr 9.

Department of Psychiatry, Faculty of Medicine, McGill University, 6875 Boulevard LaSalle, Montreal, QC H4H 1R3, Canada; Douglas Mental Health University Institute, Montreal, QC Canada. Electronic address:

Background: Child maltreatment predicts a significant risk factor for depression. The relationship between child maltreatment and depression has been shown to vary as a function of genetic factors. There have been very few systematic reviews conducted to date to synthesize what DNA methylations and/ or genetic variations interact with childhood maltreatment in the course of depression. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.049DOI Listing
April 2019
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Leisure time physical activity reduces the association between TV-viewing and depressive symptoms: A large study among 59,401 Brazilian adults.

J Affect Disord 2019 Mar 22;252:310-314. Epub 2019 Mar 22.

Department of Physical Education, Federal University of Sergipe - UFS, São Cristóvão, Brazil.

Background: Both physical activity (PA) and TV-viewing are associated with depressive symptoms, but the combined association with depressive symptoms is unclear. Therefore, our aim was to analyze the joint association of PA and TV-viewing with depressive symptoms among a large cohort of adults.

Methods: We used data from the Brazilian National Survey, conducted in 2013 with 59,401 adults [≥18 years (34,282 women)]. Read More

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http://dx.doi.org/10.1016/j.jad.2019.03.066DOI Listing
March 2019
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Physical activity and depression symptoms in women with chronic illness and the mediating role of health-related quality of life.

J Affect Disord 2019 Apr 8;252:294-299. Epub 2019 Apr 8.

University of Technology Sydney, Faculty of Health, PO Box 123 Broadway NSW 2007, Ultimo, NSW, Australia.

Background: The aim of this study was to determine the impact of physical activity on depression symptom severity in women 45 years and older with a chronic illness diagnosis, and explore relations between physical activity and psychological and health-related characteristics predicting depression symptoms.

Methods: 1932 women diagnosed with one of five chronic illnesses: asthma, depression, diabetes, osteoarthritis, or osteoporosis participated in a sub-study of the 45 and Up Study-a cross-sectional study of people aged 45 years and older. The survey included items measuring demographics, depression symptoms, health-related quality of life (HRQoL), health-related hardiness, sleep quality, and health behaviours, such as physical activity. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01650327183161
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http://dx.doi.org/10.1016/j.jad.2019.04.057DOI Listing
April 2019
3 Reads
3.383 Impact Factor

How does childhood maltreatment influence ensuing cognitive functioning among people with the exposure of childhood maltreatment? A systematic review of prospective cohort studies.

J Affect Disord 2019 Apr 9;252:278-293. Epub 2019 Apr 9.

Department of Psychiatry, Faculty of Medicine, McGill University, 6875 boulevard LaSalle, Montreal, QC H4H 1R3, Canada; Douglas Mental Health University Institute, Montreal, QC Canada. Electronic address:

Background: Childhood maltreatment is closely related to normal cognitive development and ensuing adverse mental health outcomes and cognitive dysfunction. Our current comprehensive systematic review examines the relationship between childhood maltreatment and cognitive functioning focusing only on prospective studies, which allow us to draw inferences about the temporal relationships among the constructs and make causal inferences.

Methods: The databases, EMBASE, HealthStar, PsychoInfo, Medline, and Cochrane Library, were searched using a systematic methodology to identify prospective studies published up to December, 2017 to explore the relationship between childhood maltreatment and cognitive functioning. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.026DOI Listing

The gut-brain relationship: Investigating the effect of multispecies probiotics on anxiety in a randomized placebo-controlled trial of healthy young adults.

J Affect Disord 2019 Apr 8;252:271-277. Epub 2019 Apr 8.

Department of Psychology, Houston Baptist University, 7502 Fondren Rd, Houston, TX 77074, United States.

Intro: There has been an increased interest in understanding the therapeutic effect of gut-microbiota on health, particularly in mental health. However, limited research into the connection between gut-microbiota and mental health makes this study an important endeavor in exploring the effect of gut-microbiota, through probiotics intervention, on mental health like anxiety and factors related to anxiety (e.g. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.043DOI Listing

Relationships between hand-grip strength, socioeconomic status, and depressive symptoms in community-dwelling older adults.

J Affect Disord 2019 Apr 9;252:263-270. Epub 2019 Apr 9.

Department of Psychiatry, Korea University College of Medicine, Seoul, Republic of Korea. Electronic address:

Background: Depressive symptoms have been found to be associated with decreased hand-grip strength (HGS) and low socioeconomic status (SES) in older adults. We aimed to investigate the potential moderating effect of SES on the association between HGS and depressive symptoms and the potential mediating effect of HGS on the association between SES and depressive symptoms using a nationally representative sample of older adults.

Method: Data from 3169 community-dwelling adults aged 60 years or older were acquired from the Korea National Health and Nutrition Examination Survey conducted in 2014 and 2016. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.023DOI Listing

The brief assessment of cognition in affective disorders: Normative data for the Italian population.

J Affect Disord 2019 Apr 8;252:245-252. Epub 2019 Apr 8.

Department of Neurosciences and Mental Health, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy; Department of Psychiatry and Behavioural Sciences, University of Texas at Houston, USA. Electronic address:

Background: To date there are no validated tests in Italian to assess cognitive functions in Bipolar Disorder. Therefore, this study aimed to provide normative data for the Italian version of the Brief Assessment of Cognition in Affective Disorders (BAC-A), a battery targeting neuro- and affective-cognition in affective disorders.

Methods: Data were collected from 228 healthy participants (age range: 18-67; mean age: 34. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.063DOI Listing
April 2019
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Hypertension, socioeconomic status and depressive symptoms in Chinese middle-aged and older adults: Findings from the China health and retirement longitudinal study.

J Affect Disord 2019 Apr 8;252:237-244. Epub 2019 Apr 8.

China Center for Health Development Studies, Peking University, 38 Xue Yuan Road, Haidian District, Beijing 100191, China. Electronic address:

Background: This study aimed to examine the effect of diagnosed hypertension on depressive symptoms and socioeconomic status (SES) as moderator in the effect in middle-aged and older adults in China.

Methods: We used data from the nationally representative survey of China Health and Retirement Longitudinal Study, including 6273 participants free from depressive symptoms at baseline in 2011-12. We assessed the depressive symptoms based on the 10-item Center for Epidemiological Studies Depression scale. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.002DOI Listing
April 2019
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How should we phrase the depression that is not responding to antidepressants? Treatment-refractory or treatment-resistant.

Authors:
Ali Saffet Gonul

J Affect Disord 2019 Apr 9. Epub 2019 Apr 9.

Ege University, School of Medicine Department of Psychiatry, 35100 Izmir, Turkey. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2019.04.068DOI Listing

Tramadol poisoning-associated mortality.

J Affect Disord 2019 Apr 12. Epub 2019 Apr 12.

Denver Health/Rocky Mountain Poison and Drug Center, Denver, CO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2019.04.069DOI Listing

Effectiveness of a collaborative care intervention for managing major depression and chronic musculoskeletal pain in primary care: A cluster-randomised controlled trial.

J Affect Disord 2019 Apr 8;252:221-229. Epub 2019 Apr 8.

Unit for the Study and Treatment of Pain - ALGOS, and Research Center for Behavior Assessment (CRAMC), Department of Psychology, Universitat Rovira i Virgili, Tarragona, Spain; Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Tarragona, Spain.

Background: Depression and chronic musculoskeletal pain commonly occur as comorbid conditions, which increases their negative effects on health outcomes. The objective of this study was to assess the effectiveness of the DROP (DepRessiOn and Pain) programme designed for the management of major depression and chronic musculoskeletal pain in primary care.

Methods: A cluster-randomised controlled trial was carried out between June 2015 and December 2017 with 328 patients with major depression and chronic musculoskeletal pain, randomly allocated to either intervention arm or usual care arm. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01650327183294
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http://dx.doi.org/10.1016/j.jad.2019.04.004DOI Listing
April 2019
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Comparison and change of defense mechanisms over the course of psychotherapy in patients with depression or anxiety disorder: Evidence from a randomized controlled trial.

J Affect Disord 2019 Apr 8;252:212-220. Epub 2019 Apr 8.

Department of Clinical Psychology and Psychotherapy, University of Bern, Fabrikstrasse 8, 3012 Bern, Switzerland.

Background: Defense mechanisms play an important role in the development and maintenance of both health and psychopathology. Research is still in the early stages of investigating the specific relationships among diagnostic groups and defense mechanisms along with their response to different treatment types.

Methods: For the present study a total of 47 outpatients diagnosed with depression or anxiety disorders were randomized to receive 25±3 sessions of cognitive-behavioral therapy with integrated elements of either emotion-focused therapy (CBT + EFT) or treatment components based on self-regulation theory (CBT + SR). Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.021DOI Listing

Comparison of 71 bipolar disorder pharmacotherapies for kidney disorder risk: The potential hazards of polypharmacy.

J Affect Disord 2019 Apr 8;252:201-211. Epub 2019 Apr 8.

Department of Internal Medicine, Center for Global Health, University of New Mexico Health Sciences Center, Albuquerque, NM, USA; Department of Internal Medicine, Division of Translational Informatics, University of New Mexico Health Sciences Center, Albuquerque, NM, USA. Electronic address:

Background: This study compared the largest set of bipolar disorder pharmacotherapies to date (71 drugs and drug combinations) for risk of kidney disorders (KDs).

Methods: This retrospective observational study used the IBM MarketScan® database to analyze data on 591,052 adults with bipolar disorder without prior nephropathy, for onset of KDs (of "moderate" or "high" severity) following psychopharmacotherapy (lithium, mood stabilizing anticonvulsants [MSAs], antipsychotics, antidepressants), or "No drug". Cox regression models included fixed pre-treatment covariates and time-varying drug exposure covariates to estimate the hazard ratio (HR) of each treatment versus "No drug". Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.009DOI Listing
April 2019
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The effect of treatment response on endothelial function and arterial stiffness in depression. A prospective study.

J Affect Disord 2019 Apr 9;252:190-200. Epub 2019 Apr 9.

Department of Clinical Therapeutics, Vascular Laboratory, Alexandra Hospital, Medical School, National and Kapodistrian University of Athens, 80 Vas. Sofias Str, Athens 11528, Greece; Cardiovascular Research Centre, Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, UK. Electronic address:

Background: Major depression is associated with endothelial dysfunction and arterial stiffening, which may mediate development of hypertension and increased cardiovascular risk. The effect of response to antidepressant treatment on these vascular parameters has not been elucidated.

Aims: We aimed to assess the net effect of antidepressant therapy on endothelial function and arterial stiffness in patients with psychotic depression. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.024DOI Listing

Low working memory capacity in euthymic bipolar I disorder: No relation to reappraisal on emotion regulation.

J Affect Disord 2019 Apr 8;252:174-181. Epub 2019 Apr 8.

Department of Psychiatry, Yonsei University College of Medicine, Seoul, Republic of Korea; Institute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address:

Background: Emotion regulation (ER) applies behavioral and cognitive strategies to modify the appearance and intensity of emotions. Working memory capacity (WMC) plays an important role in the ER process, particularly through its influence on the efficiency of ER strategies.

Methods: We investigated interactions between WMC and three ER strategies, namely cognitive reappraisal, expressive suppression, and rumination, in 43 euthymic patients with bipolar I disorder and 48 healthy control subjects. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.042DOI Listing
April 2019
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Dietary patterns and attention deficit/hyperactivity disorder (ADHD): A systematic review and meta-analysis.

J Affect Disord 2019 Apr 10;252:160-173. Epub 2019 Apr 10.

Postgraduate Program in Epidemiology, Federal University of Pelotas, Rua Marechal Deodoro, 1160, 3 piso, Pelotas, RS, Brazil.

Background: The Attention Deficit Hyperactivity Disorder (ADHD) is a neurobiological disorder characterized by persistent symptoms of inattention, impulsivity and hyperactivity. The diet during childhood has been investigated as a factor potentially involved in the ADHD etiology.

Objective: To review systematically the evidence of the association between dietary patterns and ADHD. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01650327183297
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http://dx.doi.org/10.1016/j.jad.2019.04.061DOI Listing
April 2019
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Effects of early life adversity and FKBP5 genotype on hippocampal subfields volume in major depression.

J Affect Disord 2019 Apr 9;252:152-159. Epub 2019 Apr 9.

Department of Psychiatry and Psychotherapy, Otto von Guericke University, Magdeburg, Germany; Department of Psychiatry, University of Dublin, Trinity College, Dublin, Ireland. Electronic address:

Background: Smaller hippocampus volume represents a consistent finding in major depression (MDD). Hippocampal neuroplasticity due to chronic stress might have differential effect on hippocampal subfields. We investigated the effects of the rs1360780 polymorphism of the hypothalamic-pituitary-axis related gene FKBP5 in combination with early life stress (ELA) on the structure of hippocampal subfields in MDD. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.054DOI Listing

The anaesthetic-ECT time interval with thiopentone-Impact on seizure quality.

J Affect Disord 2019 Apr 9;252:135-140. Epub 2019 Apr 9.

School of Psychiatry, University of New South Wales (UNSW), Hospital Road, Randwick, New South Wales 2031, Australia; Black Dog Institute, Hospital Road, Randwick, New South Wales2031, Australia; The Wesley Hospital, 7 Blake St, Kogarah, New South Wales 2217, Australia; St. George Hospital, Gray St, Kogarah, New South Wales 2217, Australia.

Background: The time between anaesthetic induction and ECT stimulus administration has been hypothesised to significantly impact ictal EEG quality. In this study, our aim was to examine the effect of the time interval between anaesthetic induction and the ECT stimulus for ictal seizure quality in ECT sessions utilising thiopentone anaesthesia.

Methods: 413 EEG traces from 42 patients, collected retrospectively, were manually rated using a quantitative-qualitative structured rating scale (indices including seizure amplitude, regularity, post-ictal suppression and general seizure quality). Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.027DOI Listing
April 2019
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Predictors of response and remission in a naturalistic inpatient sample undergoing multimodal treatment for depression.

J Affect Disord 2019 Apr 8;252:99-106. Epub 2019 Apr 8.

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Klinik für Psychiatrie und Psychotherapie, Campus Benjamin Franklin, Hindenburgdamm 30, 12203 Berlin, Germany.

Background: Many depressed patients do not achieve response or remission despite adequate treatment. Identifying predictors of outcome can contribute to developing therapeutic algorithms for difficult-to-treat depression. Therefore, we examined clinical predictors of response and remission in a naturalistic inpatient sample undergoing multimodal treatment for depression. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.044DOI Listing

Prevalence of major depressive disorder and its socio-demographic correlates in the general adult population in Hebei province, China.

J Affect Disord 2019 Mar 18;252:92-98. Epub 2019 Mar 18.

Unit of Psychiatry, Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macao SAR, China. Electronic address:

Background: Major depressive disorder (MDD) is a common psychiatric disorder which is associated with significant disability and psychosocial factors. There are only few epidemiological studies of MDD in economically underdeveloped regions of China. This study examined the 1-month and lifetime prevalence of MDD and their sociodemographic correlates in Hebei province, China. Read More

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http://dx.doi.org/10.1016/j.jad.2019.01.049DOI Listing
March 2019
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Psychological interventions for young people at risk for bipolar disorder: A systematic review.

J Affect Disord 2019 Apr 9;252:84-91. Epub 2019 Apr 9.

School of Psychiatry, University of New South Wales, Sydney, Australia.

Objectives: Several studies have recently been conducted that have explored the benefits of psychological interventions in reducing symptomatology or improving outcomes in young people at-risk of developing bipolar disorder. The aim of this review was to explore if such interventions reduce current psychiatric symptoms and prevent the development of new symptoms.

Methods: A systematic review was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.058DOI Listing
April 2019
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Abnormal coupling among spontaneous brain activity metrics and cognitive deficits in major depressive disorder.

J Affect Disord 2019 Apr 8;252:74-83. Epub 2019 Apr 8.

Department of Radiology, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China. Electronic address:

Background: A variety of functional metrics derived from resting-state functional magnetic resonance imaging (rs-fMRI) have been employed to explore spontaneous brain activity changes in major depressive disorder (MDD) and have enjoyed significant success in unraveling the neurobiological mechanisms underlying this disorder. However, it is unclear whether spatial and temporal coupling relationships among these rs-fMRI metrics are altered in MDD.

Methods: 50 patients with MDD and 36 well-matched healthy controls underwent rs-fMRI scans. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.030DOI Listing
April 2019
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Depression in adolescent girls: Relationship to serum vitamins a and E, immune response to heat shock protein 27 and systemic inflammation.

J Affect Disord 2019 Apr 8;252:68-73. Epub 2019 Apr 8.

Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address:

Background: The inflammation and oxidative stress are thought to play an important role in the etiopathogenesis of some psychological disorders. We aimed to assess the potential relationships between serum fat soluble vitamins (Vitamins A and E), antibody titers to Hsp27 (anti-Hsp27) and hematological markers of inflammation, with mood disorders in a population of adolescent girls.

Methods: A total of 563 adolescent girls (Age 12-18 years) were included in the study. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.048DOI Listing
April 2019
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Allergic rhinitis increases the risk of incident panic disorder among young individuals: A nationwide population-based cohort study in Taiwan.

J Affect Disord 2019 Apr 9;252:60-67. Epub 2019 Apr 9.

Tsaotun Psychiatric Center, Ministry of Health and Welfare, 542 No.161, Yu-Pin Rd, Caotun Township, Nantou, Taiwan, R.O.C.. Electronic address:

Background: Studies have reported an association between allergy and panic disorder. However, few studies have explored the relationship between allergic rhinitis and panic disorder. Previous studies were limited by cross-sectional study designs, self-reported symptoms, absence of matched controls, and lack of consideration of the influence of steroid and comorbidities. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.037DOI Listing
April 2019
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