1,459 results match your criteria Journal of Renal Nutrition[Journal]


High-Resistant Starch, Low-Protein Flour Intervention on Patients With Early Type 2 Diabetic Nephropathy: A Randomized Trial.

J Ren Nutr 2019 Apr 11. Epub 2019 Apr 11.

Department of Nutrition, Shandong Provincial Hospital, Jinan, China; Department of Nutrition and Food Hygiene, School of Public health, Shandong University, Jinan, China. Electronic address:

Objective: The objective of this study is to explore the effect of high-resistant starch (RS), low-protein flour as a source of RS on patients with early type 2 diabetic nephropathy (DN) through the clinical intervention trial.

Design: This was a single center, randomized, comparative, open-label trial. Seventy-five patients with early DN, aged 18 to 80 y, were recruited and randomly assigned to two groups. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10512276183028
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http://dx.doi.org/10.1053/j.jrn.2018.12.005DOI Listing
April 2019
6 Reads

Clinical Taste Perception Test for Patients With End-Stage Kidney Disease on Dialysis.

J Ren Nutr 2019 Apr 9. Epub 2019 Apr 9.

Unidad de Investigación Médica en Enfermedades Renales, Hospital de Especialidades, CMNO, IMSS, Guadalajara, México. Electronic address:

Objective: The aim of this study was to validate a direct taste perception test (TPT) and evaluate its performance in patients on dialysis.

Methods: This cross-sectional study was carried out in a tertiary-care hospital. A TPT was validated on 112 healthy subjects and applied on 43 patients on hemodialysis and 32 patients on peritoneal dialysis. Read More

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http://dx.doi.org/10.1053/j.jrn.2019.02.003DOI Listing

Bioimpedance Underestimates Bone Mineral Content in Association With High Levels of Phosphate.

J Ren Nutr 2019 Apr 6. Epub 2019 Apr 6.

Universidade Nove de Julho, UNINOVE, São Paulo, Brazil; Nephrology Division, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, São Paulo, Brazil. Electronic address:

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http://dx.doi.org/10.1053/j.jrn.2019.02.005DOI Listing

Bowel Habits and the Association With Uremic Toxins in Non-Dialysis-Dependent Chronic Kidney Disease Patients.

J Ren Nutr 2019 Apr 4. Epub 2019 Apr 4.

Nutrition Program, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil; Hospital do Rim - Fundação Oswaldo Ramos, São Paulo, Brazil; Division of Nephrology, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil. Electronic address:

Objective: The aim of this study is to evaluate the association between bowel habits and microbial-derived uremic toxins p-cresyl sulfate (PCS) and indoxyl sulfate (IS) in patients with non-dialysis-dependent chronic kidney disease (NDD-CKD).

Design And Methods: This is a cross-sectional analysis including 43 nondiabetic NDD-CKD patients (58% men; 59.0 ± 13. Read More

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http://dx.doi.org/10.1053/j.jrn.2019.02.004DOI Listing

Synergistic Effect of Inflammatory Cytokines and Body Adiposity on Insulin Resistance and Endothelial Markers in Patients With Stages 3-5 Chronic Kidney Disease.

J Ren Nutr 2019 Apr 4. Epub 2019 Apr 4.

Nephrology Division, Rio de Janeiro State University, Rio de Janeiro, Brazil.

Background: High body adiposity, inflammatory cytokines, insulin resistance (IR), and the endothelial markers-soluble intercellular adhesion molecule-1 (sICAM-1) and soluble vascular adhesion molecule-1 (sVCAM-1)-are among cardiovascular risk factors observed in chronic kidney disease (CKD). Synergistic interaction of inflammatory cytokines with adiposity on IR, sICAM-1, and sVCAM-1 has not been reported in nondialysis-dependent CKD (NDD-CKD) patients. Thus the study aim was to evaluate the interaction of inflammatory cytokines on the association of body adiposity with the cardiometabolic risk factors-IR, sICAM-1, and sVCAM-1-in NDD-CKD patients. Read More

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http://dx.doi.org/10.1053/j.jrn.2019.02.001DOI Listing
April 2019
1 Read

Effects of Low Protein Diet on Nuclear Factor Erythroid 2-Related Factor 2 Gene Expression in Nondialysis Chronic Kidney Disease Patients.

J Ren Nutr 2019 Apr 4. Epub 2019 Apr 4.

Graduate Program in Cardiovascular Sciences, Fluminense Federal University (UFF), Niterói, Rio de Janeiro, Brazil; Graduate Program in Medical Sciences, Fluminense Federal University (UFF), Niterói, Rio de Janeiro, Brazil; Graduate Program in Nutrition Sciences, Fluminense Federal University (UFF), Niterói, Rio de Janeiro, Brazil.

Objective(s): Low protein diets (LPD; 0.6 g/kg/day), prescribed for nondialysis chronic kidney disease (CKD) patients, have demonstrated numerous benefits. LPDs may modulate inflammation and oxidative stress through the nuclear factor erythroid 2-related factor 2 (Nrf2), which encodes antioxidant and phase II detoxifying enzymes. Read More

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http://dx.doi.org/10.1053/j.jrn.2019.01.005DOI Listing

Estimating 24-Hour Urinary Sodium Excretion From Spot Urine Samples in Chronic Kidney Disease Patients.

J Ren Nutr 2019 Apr 4. Epub 2019 Apr 4.

Department of Nephrology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China; Shanghai Medical Center of Kidney, Shanghai, People's Republic of China; Shanghai Institute of Kidney and Dialysis, Shanghai, People's Republic of China; Shanghai Key Laboratory of Kidney and Blood Purification, Shanghai, People's Republic of China; Hemodialysis Quality Control Center of Shanghai, Shanghai, People's Republic of China. Electronic address:

Objective: Spot urine sodium and associated estimating equations provide a suitable alternative assessment of 24-hour sodium excretion in many large-scale studies, but not in chronic kidney disease (CKD) patients with decreased renal function. Herein, we aimed to develop a novel predictive equation.

Design And Methods: We retrospectively enrolled all CKD patients at Stage 1-4 who received spot and 24-hour urinary analysis in our single center from January 1, 2014 to December 31, 2017. Read More

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http://dx.doi.org/10.1053/j.jrn.2019.02.002DOI Listing
April 2019
1 Read

Diabetes and Chronic Kidney Disease Basics: Part One.

Authors:
Amy Hess Fischl

J Ren Nutr 2019 Mar 17. Epub 2019 Mar 17.

Certified Diabetes Educator, Chicago, Illinois. Electronic address:

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http://dx.doi.org/10.1053/j.jrn.2019.01.014DOI Listing
March 2019
1 Read

Geriatric Nutritional Risk Index Is Predictive of Subjective Global Assessment and Dialysis Malnutrition Scores in Elderly Patients on Hemodialysis.

J Ren Nutr 2019 Mar 7. Epub 2019 Mar 7.

Division of Nephrology and Hemodialysis, Humanitas Clinical and Research Hospital, Rozzano, Milan, Italy.

Objective: Malnutrition is a frequent complication in patients on hemodialysis (HD), even if its adequate appraisal remains one of the most complicated challenges in the HD scenario because of the limits of current malnutrition biomarkers. The aim of our study was to assess the relation of subjective nutritional tools Subjective Global Assessment (SGA) and Dialysis Malnutrition Score (DMS) with the objective malnutrition tool Geriatric Nutritional Risk Index (GNRI) in elderly patients on HD.

Methods: This is a cross-sectional study involving 71 patients on maintenance HD. Read More

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http://dx.doi.org/10.1053/j.jrn.2019.01.012DOI Listing

Successful Kidney Transplantation Is Associated With Weight Gain From Truncal Obesity and Insulin Resistance.

J Ren Nutr 2019 Mar 6. Epub 2019 Mar 6.

Division of Nephrology, Baylor College of Medicine, Houston, Texas.

Objective: The objective of this study is to compare changes in body composition, lifestyle factors, and metabolic responses occurring in living kidney transplant recipient patients after transplantation.

Design And Methods: The study was a single-site, prospective, observational study. To identify metabolic responses during the initial years after transplantation, we obtained state-of-the-art, high-resolution measurements of body composition from a 4-compartment model using dual-energy X-ray absorptiometry, air displacement plethysmography, and total body potassium and nitrogen counters. Read More

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http://dx.doi.org/10.1053/j.jrn.2019.01.009DOI Listing
March 2019
1 Read

Body Fat Estimation in Kidney Transplant Recipients: Skinfolds Thickness Compared With Dual-Energy X-Ray Absorptiometry.

J Ren Nutr 2019 Mar 6. Epub 2019 Mar 6.

Life Sciences Knowledge Area, Universidade de Caxias do Sul, Caxias do Sul, Rio Grande do Sul, Brazil; Post-Graduation Program in Medical Sciences: Endocrinology, School of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil. Electronic address:

Objective(s): The aim of the study was to compare the method of estimating the body fat percentage (BF%) by skinfold thickness to dual-energy X-ray absorptiometry (DEXA) in kidney transplant recipients.

Design And Methods: This is a longitudinal study that evaluated patients at 3 (n = 46) and 12 months (n = 37) after kidney transplantation at Hospital de Clínicas in Porto Alegre, Brazil. The Durnin and Womersley equation was used to estimate the body density, and the Siri equation was used to estimate BF%, using measurements of 4 skinfolds: biceps, triceps, subscapular, and suprailiac. Read More

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http://dx.doi.org/10.1053/j.jrn.2019.01.010DOI Listing
March 2019
1 Read

Prediction of Mortality and Hospitalization Risk Using Nutritional Indicators and Their Changes Over Time in a Large Prevalent Hemodialysis Cohort.

J Ren Nutr 2019 Mar 6. Epub 2019 Mar 6.

Fresenius Medical Care North America, Waltham, Massachusetts.

Objective(s): Malnutrition and protein-energy wasting are associated with morbidity and mortality in hemodialysis patients. Existing nutritional scores rely primarily on cross-sectional data. Using readily available nutritional indicators, we developed models to predict the risk of mortality and hospitalization in prevalent hemodialysis patients. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10512276193003
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http://dx.doi.org/10.1053/j.jrn.2019.01.013DOI Listing
March 2019
3 Reads
2.548 Impact Factor

Alcohol Consumption and Incident Kidney Disease: Results From the Atherosclerosis Risk in Communities Study.

J Ren Nutr 2019 Mar 5. Epub 2019 Mar 5.

Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, Maryland; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland. Electronic address:

Objective(s): Moderate alcohol consumption has been found to be associated with lower risk of coronary heart disease and myocardial infarction, which share similar risk factors and pathophysiology with chronic kidney disease (CKD). However, there is inconsistent evidence on the association between alcohol consumption and CKD.

Design And Methods: We conducted a prospective analysis of 12,692 participants aged 45-64 years from the Atherosclerosis Risk in Communities (ARIC) study. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10512276193002
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http://dx.doi.org/10.1053/j.jrn.2019.01.011DOI Listing
March 2019
7 Reads

Phosphate Binders and Nonphosphate Effects in the Gastrointestinal Tract.

J Ren Nutr 2019 Mar 4. Epub 2019 Mar 4.

Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana; Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, Indiana; Department of Medicine, Roudebush Veterans Affairs Medical Center, Indianapolis, Indiana. Electronic address:

Phosphate binders are commonly prescribed in patients with end-stage kidney disease to prevent and treat hyperphosphatemia. These binders are usually associated with gastrointestinal distress, may bind molecules other than phosphate, and may alter the gut microbiota, altogether having systemic effects unrelated to phosphate control. Sevelamer is the most studied of the available binders for nonphosphate-related effects including binding to bile acids, endotoxins, gut microbiota-derived metabolites, and advanced glycation end products. Read More

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http://dx.doi.org/10.1053/j.jrn.2019.01.004DOI Listing
March 2019
1 Read

Handgrip Strength as a Predictor of All-Cause Mortality in Patients With Chronic Kidney Disease Undergoing Dialysis: A Meta-Analysis of Prospective Cohort Studies.

J Ren Nutr 2019 Feb 28. Epub 2019 Feb 28.

Department of Sport Industry Studies, Yonsei University, Seoul, Korea; Exercise Medicine Center for Diabetes and Cancer Patients, Institute of Convergence of Science (ICONS), Yonsei University, Seoul, Korea. Electronic address:

The aim of this study was to conduct a meta-analysis of the association between handgrip strength (HGS) and all-cause mortality in patients with chronic kidney disease undergoing dialysis. We evaluated eligible studies by searching PubMed and EMBASE databases up to December 2, 2018. A total of 9 prospective cohort studies were included in this meta-analysis. Read More

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http://dx.doi.org/10.1053/j.jrn.2019.01.002DOI Listing
February 2019
4 Reads
2.548 Impact Factor

Association Between Serum Prealbumin Level and Outcomes in Prevalent Kidney Transplant Recipients.

J Ren Nutr 2019 May 26;29(3):188-195. Epub 2019 Feb 26.

Division of Nephrology, Department of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee; James D Eason Transplant Institute, Methodist University Hospital, Memphis, Tennessee; Division of Transplant Surgery, Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee; Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary. Electronic address:

Objective(s): Prealbumin, a transport protein mostly synthesized in the liver, is a marker of nutrition. Although decreased prealbumin levels are associated with increased mortality in end-stage kidney disease patients, its association with mortality in kidney transplant recipients remains unknown. We evaluated the association between prealbumin levels and outcomes in kidney transplant recipients. Read More

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http://dx.doi.org/10.1053/j.jrn.2019.01.003DOI Listing
May 2019
2.548 Impact Factor

The Effects of OMEGA-3 Fatty Acid Supplementation Upon Interleukin-12 and Interleukin-18 in Chronic Kidney Disease Patients.

J Ren Nutr 2019 Feb 22. Epub 2019 Feb 22.

Medical School, University of Western Australia, Perth, Australia; Department of Nephrology, Sir Charles Gairdner Hospital, Perth, Australia.

Objective(s): Cardiovascular disease (CVD) remains a leading cause of mortality in chronic kidney disease (CKD) patients. Interventions targeting traditional risk factors have largely proven ineffective in CKD patients in part because of the increased role of nontraditional risk factors such as chronic inflammation. Omega-3 fatty acids (ω3FA) are inexpensive and safe natural agents, which target inflammation and have potential cardioprotective benefits. Read More

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http://dx.doi.org/10.1053/j.jrn.2019.01.001DOI Listing
February 2019

Does Kidney Longevity Mean Healthy Vegan Food and Less Meat or Is Any Low-Protein Diet Good Enough?

J Ren Nutr 2019 Mar;29(2):79-81

Director Clinical Research, Department of Surgery, Houston Methodist Hospital, Houston, Texas USA.

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http://dx.doi.org/10.1053/j.jrn.2019.01.008DOI Listing
March 2019
2.548 Impact Factor

Message From the Chair of the Council on Renal Nutrition.

J Ren Nutr 2019 Mar;29(2):164-165

Children's Healthcare of Atlanta. Electronic address:

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http://dx.doi.org/10.1053/j.jrn.2019.01.007DOI Listing

Sociodemographic and Kidney Disease Correlates of Nutrient Intakes Among Urban African Americans With Uncontrolled Hypertension.

J Ren Nutr 2019 Jan 29. Epub 2019 Jan 29.

Division of General Internal Medicine, Duke University School of Medicine, Durham, North Carolina.

Objective: The objective of this study was to determine the association between sociodemographic factors and intakes of 4 nutrients and associations between intakes and markers of kidney disease to identify opportunities to improve outcomes among clinically high-risk African Americans.

Design And Methods: We conducted a cross-sectional study of baseline data from the Achieving Blood Pressure Control Together study, a randomized controlled trial of 159 African Americans (117 females) with uncontrolled hypertension in Baltimore MD. To determine the association between sociodemographic factors and nutrient intakes, we constructed linear and logistic regression models. Read More

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http://dx.doi.org/10.1053/j.jrn.2018.12.004DOI Listing
January 2019
4 Reads

Chronic Kidney Disease and the Adiposity Paradox: Valid or Confounded?

J Ren Nutr 2019 Jan 29. Epub 2019 Jan 29.

Department of Medicine, Stanford University School of Medicine, Stanford, California; Department of Pediatrics, Stanford University School of Medicine, Stanford, California.

Objective: Obesity, defined by body mass index (BMI), is associated with lower mortality risk in patients with chronic kidney disease (CKD). BMI and % body fat (%BF) are confounded by muscle mass, while DXA derived fat mass index (FMI) overcomes this limitation. We compared the associations between obesity and mortality in persons with CKD using multiple estimates of adiposity, and determined whether muscle mass, inflammation and weight loss modify these associations. Read More

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http://dx.doi.org/10.1053/j.jrn.2018.11.011DOI Listing
January 2019
4 Reads

Your Guide to Create a Balanced Kidney-Friendly Meal.

J Ren Nutr 2019 Jan 29. Epub 2019 Jan 29.

Ann Arbor, Michigan.

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http://dx.doi.org/10.1053/j.jrn.2018.12.003DOI Listing
January 2019

Dietary Total Antioxidant Capacity and the Risk of Chronic Kidney Disease in Patients With Type 2 Diabetes: A Nested Case-Control Study in the Tehran Lipid Glucose Study.

J Ren Nutr 2019 Jan 29. Epub 2019 Jan 29.

Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Objective: Dietary total antioxidant capacity (DTAC) has been hypothesized as being involved in health promotion and disease prevention. However, data about the association of the DTAC (as estimated by ferric reducing antioxidant power) with diabetes chronic complications are scarce. Therefore, the aim of this study was to determine the associations between the DTAC and chronic kidney disease (CKD) risk in subjects with type 2 diabetic. Read More

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http://dx.doi.org/10.1053/j.jrn.2018.11.008DOI Listing
January 2019

The Effect of Short-Term Vitamin D Supplementation on Calcium Status in Vitamin D Insufficient Renal Transplant Recipients at Risk of Hypercalcemia.

J Ren Nutr 2019 May 25;29(3):181-187. Epub 2019 Jan 25.

Department of Renal Medicine, Cork University Hospital, Cork, Ireland; HRB Clinical Research Facility, University College Cork, Cork, Ireland.

Objective: Vitamin D insufficiency is highly prevalent among renal transplant recipients and in observational studies is associated with adverse outcomes. Hypercalcemia, usually due to persistent hyperparathyroidism, also commonly occurs in this population and often coexists with vitamin D insufficiency. However, concern that vitamin D supplementation might exacerbate the pre-existing hypercalcemia often leads clinicians to avoid vitamin D supplementation in such patients. Read More

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http://dx.doi.org/10.1053/j.jrn.2018.11.012DOI Listing
May 2019
1 Read

Cholecalciferol Supplementation Did Not Change Interleukin-7 and B cell-Activating Factor Levels and CD95 Expression in B lymphocytes in Patients on Dialysis: A Randomized Pilot-Controlled Trial.

J Ren Nutr 2019 Jan 24. Epub 2019 Jan 24.

Division of Nephrology- Universidade Federal São Paulo, UNIFESP, São Paulo, São Paulo, Brazil; Post-graduate Program in Medicine, Universidade Nove de Julho/UNINOVE, São Paulo, São Paulo, Brazil.

Background: End-stage renal disease results in B cell lymphopenia and low levels of vitamin D. Since the link between vitamin D deficiency and B lymphocytes dysfunction are not clear in patients with end-stage renal disease, we suggest that vitamin D adequacy and factors related to the homeostasis of these cells should be investigated. B lymphocytes homeostasis is a process mainly regulated signals of grown and death as interleukin (IL)-7, B cell-activating factor (BAFF)/BAFF-receptor and CD95 expression. Read More

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http://dx.doi.org/10.1053/j.jrn.2018.11.006DOI Listing
January 2019
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The Effect of Long-Term Cholecalciferol Supplementation on Vascular Calcification in Chronic Kidney Disease Patients With Hypovitaminosis D.

J Ren Nutr 2019 Jan 24. Epub 2019 Jan 24.

Nephrology Division, Federal University of São Paulo, São Paulo, Brazil. Electronic address:

Objective: The role of vitamin D supplementation on vascular calcification (VC) in patients with chronic kidney disease (CKD) is controversial. The objective of this study was to evaluate the effects of long-term cholecalciferol supplementation on VC in nondialysis patients with CKD stages 3-4 with hypovitaminosis D.

Design And Methods: Eighty patients aged 18-85 years with creatinine clearance between 15 and 60 mL/min/1. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10512276183028
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http://dx.doi.org/10.1053/j.jrn.2018.12.002DOI Listing
January 2019
8 Reads

Effectiveness of Intradialytic Parenteral Nutrition in Treating Protein-Energy Wasting in Hemodialysis: A Rapid Systematic Review.

J Ren Nutr 2019 Jan 24. Epub 2019 Jan 24.

Department of Veterans Affairs, VA Portland Health Care System, Evidence-based Synthesis Program (ESP) Coordinating Center, Portland, OR, USA.

Intradialytic parenteral nutrition (IDPN) is commonly requested before recommended therapies in malnourished patients on hemodialysis. This review provides updated critical synthesis of the evidence on the use of IDPN in patients on hemodialysis. We searched MEDLINE, CINAHL, and other sources to identify evidence. Read More

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http://dx.doi.org/10.1053/j.jrn.2018.11.009DOI Listing
January 2019

Myostatin and Insulin-Like Growth Factor 1 Are Biomarkers of Muscle Strength, Muscle Mass, and Mortality in Patients on Hemodialysis.

J Ren Nutr 2019 Jan 25. Epub 2019 Jan 25.

Department of Clinical Chemistry, University of Liège (ULg CHU), Liège, Belgium.

Objective: Muscle strength is frequently altered in hemodialysis patients. In the present work, five potential muscle biomarkers have been studied in their ability to assess muscular strength, muscular mass and to predict mortality of hemodialysis patients: activin-A, procollagen III N-terminal peptide, follistatin, myostatin and insulin-like growth factor-1 (IGF-1).

Design And Methods: Three independent cohorts of prevalent hemodialysis patients (2 from Liège, Belgium and 1 from Marseille, France) were considered in this observational prospective study. Read More

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http://dx.doi.org/10.1053/j.jrn.2018.11.010DOI Listing
January 2019
4 Reads

Quantifying the Time Used for Renal Dietitian's Responsibilities: A Pilot Study.

J Ren Nutr 2019 Jan 22. Epub 2019 Jan 22.

Center for Reducing Health Disparities, MetroHealth Medical Center, Case Western Reserve University, Cleveland, Ohio.

Objective: The purpose of this study was to quantify how dialysis dietitians spend their time and whether the activities that were most frequent varied based on the ratio of patient to full-time equivalent (FTE) dietitian.

Methods: This study is a cross-sectional, observational, time-and-motion study carried out using the Work Activity Measurement by Activity Timing software/method for time recording. This study was carried out in 14 dialysis centers in and around Cleveland, Ohio. Read More

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http://dx.doi.org/10.1053/j.jrn.2018.11.007DOI Listing
January 2019
1 Read

Different Effects of Iron Indices on Mortality in Patients With Autosomal Dominant Polycystic Kidney Disease After Long-Term Hemodialysis: A Nationwide Population-Based Study.

J Ren Nutr 2019 Jan 22. Epub 2019 Jan 22.

Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan R.O.C; Division of Nephrology, Department of Internal Medicine, Taipei Medical University-Shuang Ho Hospital, New Taipei City, Taiwan. Electronic address:

Objective: Iron supplementation and erythropoietin stimulating agents (ESAs) are essential for maintaining hemoglobin levels in hemodialysis patients. However, patients with autosomal-dominant polycystic kidney disease (PKD) have higher endogenous erythropoietin levels, so their recommended iron indices for hemodialysis patients may differ. This study evaluated iron profiles, including ferritin levels and transferrin saturation (TSAT) to identify factors affecting mortality in patients on dialysis, and those associated with mortality in patients with and without PKD. Read More

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http://dx.doi.org/10.1053/j.jrn.2018.11.004DOI Listing
January 2019
12 Reads

Frequency and Risk Factors of Kidney Alterations in Children and Adolescents who Are Overweight and Obese in a Primary Health-care Setting.

J Ren Nutr 2019 Jan 21. Epub 2019 Jan 21.

Unit of Medical Research in Renal Diseases, Hospital de Especialidades, CMNO, IMSS, Guadalajara, Mexico. Electronic address:

Objective: Obesity is clearly associated to kidney disease in adult population; however, there is scarce evidence in children and adolescents. The aim was to compare frequency of renal damage according to the presence of overweight-obesity in children and adolescents, as well as to compare nutritional and biochemical risk factors, according to the presence of kidney alterations.

Methods: Cross-sectional study; 172 children and adolescents, 6-16 years old, without malnutrition, diabetes mellitus, hypertension and independent comorbid conditions associated to obesity or kidney disease, as well as transitory causes of microalbuminuria (MA) from a Primary Health-Care Unit were included. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10512276183027
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http://dx.doi.org/10.1053/j.jrn.2018.11.005DOI Listing
January 2019
14 Reads

One-Year Historical Cohort Study of the Phosphate Binder Sucroferric Oxyhydroxide in Patients on Maintenance Hemodialysis.

J Ren Nutr 2019 Jan 21. Epub 2019 Jan 21.

University of California Irvine, School of Medicine, Orange, California. Electronic address:

Objective: The high pill burden of many phosphate binders (PBs) may contribute to increased prevalence of hyperphosphatemia and poor nutritional status observed among patients undergoing maintenance hemodialysis therapy. We examined the real-world effectiveness of sucroferric oxyhydroxide (SO), a PB with low pill burden, in managing serum phosphorus in patients with prevalent hemodialysis over a 1-year period.

Design: Historical cohort analyses of de-identified electronic medical records. Read More

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http://dx.doi.org/10.1053/j.jrn.2018.11.002DOI Listing
January 2019
3 Reads
2.548 Impact Factor

Association of Pre-End-Stage Renal Disease Serum Albumin With Post-End-Stage Renal Disease Outcomes Among Patients Transitioning to Dialysis.

J Ren Nutr 2019 Jan 11. Epub 2019 Jan 11.

Harold Simmons Center for Kidney Disease Research and Epidemiology, Division of Nephrology and Hypertension, Department of Medicine, University of California Irvine, School of Medicine, Orange, California; Nephrology Section, Tibor Rubin VA Medical Center, Long Beach, California. Electronic address:

Objective: Serum albumin is a marker of malnutrition and inflammation and has been demonstrated as a strong predictor of mortality in chronic kidney disease (CKD) and end-stage renal disease (ESRD) patients. Yet, whether serum albumin levels in late-stage CKD are associated with adverse outcomes after the transition to ESRD is unknown. We hypothesize that lower levels and a decline in serum albumin in late-stage CKD are associated with higher risk of mortality and hospitalization rates 1 year after transition to ESRD. Read More

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http://dx.doi.org/10.1053/j.jrn.2018.09.004DOI Listing
January 2019
1 Read
2.548 Impact Factor

Low-Fiber Intake Is Associated With High Production of Intraperitoneal Inflammation Biomarkers.

J Ren Nutr 2019 Jan 11. Epub 2019 Jan 11.

School of Medicine, Pontifical Catholic University of Paraná (PUCPR), Curitiba, Brazil.

Objective: Fiber intake influences disturbances in the gastrointestinal tract and is associated with systemic inflammation in the general population. Systemic and intraperitoneal inflammation play an important role in defining outcomes in peritoneal dialysis (PD), but the relationship between dietary fiber intake and inflammatory biomarkers has not yet been reported in the population on PD. The objective of the present study is to analyze whether or not fiber intake in patients on PD is associated with serum and intraperitoneal levels of inflammatory biomarkers. Read More

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http://dx.doi.org/10.1053/j.jrn.2018.10.013DOI Listing
January 2019
1 Read

Carbohydrate and Lipid Prescription, Administration, and Oxidation in Critically Ill Patients With Acute Kidney Injury: A Post Hoc Analysis.

J Ren Nutr 2019 Jan 7. Epub 2019 Jan 7.

Department of General Intensive Care and Institute for Nutrition Research, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Objective: In a prospective multicenter study on adult patients with acute kidney injury (AKI) receiving enteral and/or parenteral nutrition, administered carbohydrates and lipids were compared to the prescribed amounts, as well as to substrate utilization data derived from indirect calorimetry measurements.

Methods: Resting energy expenditure (REE) was measured by indirect calorimetry. Nitrogen excretion was obtained from the protein catabolic rate calculated from urinary urea nitrogen when available and by urea kinetic-based methods in patients on renal replacement therapy. Read More

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http://dx.doi.org/10.1053/j.jrn.2018.09.002DOI Listing
January 2019
3 Reads

Food Consumption in Chronic Kidney Disease: Association With Sociodemographic and Geographical Variables and Comparison With Healthy Individuals.

J Ren Nutr 2018 Dec 24. Epub 2018 Dec 24.

Nutrition Institute, Rio de Janeiro State, University, Rio de Janeiro, Brazil. Electronic address:

Objective: To describe the food consumption of individuals with chronic kidney disease (CKD) per sociodemographic and geographical characteristics and CKD treatment. In addition, we compared the food consumption of individuals with and without CKD.

Methods: Cross-sectional study using data from the National Health Survey (Brazil 2013) that included 60,202 individuals. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10512276183025
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http://dx.doi.org/10.1053/j.jrn.2018.10.010DOI Listing
December 2018
6 Reads

Dietary Sodium Reduction Reduces Albuminuria: A Cluster Randomized Trial.

J Ren Nutr 2018 Dec 24. Epub 2018 Dec 24.

The George Institute for Global Health, UNSW, Sydney, Australia.

Objectives: The objective of the study was to assess the impact of sustained dietary salt reduction on albuminuria in nearly 2000 community-dwelling adults.

Design And Methods: The present study is a prespecified secondary analysis of the China Rural Health Initiative Salt Reduction Study cluster randomized trial undertaken in 120 villages in rural China. Villages were randomized to a sodium reduction program of education and access to reduced-sodium salt substitute or control. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10512276183024
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http://dx.doi.org/10.1053/j.jrn.2018.10.009DOI Listing
December 2018
10 Reads

Decline in the Functional Status and Mortality in Patients on Hemodialysis: Results from the Japan Dialysis Outcome and Practice Patterns Study.

J Ren Nutr 2018 Dec 24. Epub 2018 Dec 24.

Division of Nephrology, Endocrinology and Metabolism, Tokai University School of Medicine, Isehara, Japan.

Objectives: Patients with end-stage renal disease (ESRD) treated with hemodialysis suffer a high burden of poor functional status. Poor functional status is known as a strong, consistent predictor of mortality. However, little is known about the trajectory of functional status and its association with clinical outcomes in the ESRD population. Read More

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http://dx.doi.org/10.1053/j.jrn.2018.10.012DOI Listing
December 2018
2 Reads

Message From the Council on Renal Nutrition Chair.

J Ren Nutr 2019 Jan;29(1):76-77

NKF CRN Chair 2018-2019. Electronic address:

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http://dx.doi.org/10.1053/j.jrn.2018.10.002DOI Listing
January 2019
1 Read

Opportunities for Renal Nutrition and Metabolism at the Dawn of 2020s: An Inauguration Message From the New JREN Editors-In-Chief.

J Ren Nutr 2019 Jan;29(1)

International Society of Renal Nutrition and Metabolism.

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http://dx.doi.org/10.1053/j.jrn.2018.11.003DOI Listing
January 2019
2 Reads
2.548 Impact Factor

Phase Angle Is Associated With Handgrip Strength but Not With Sarcopenia in Kidney Transplantation Patients.

J Ren Nutr 2019 May 21;29(3):196-204. Epub 2018 Dec 21.

School of Medicine, Federal University of Uberlandia (UFU), Uberlandia, Minas Gerais, Brazil. Electronic address:

Objectives: Phase angle (PhA) is a cell health marker and has been associated with muscle mass and strength in non-kidney disease individuals. However, it is unknown whether PhA is a predictor of sarcopenia and its components in kidney transplantation patients. The aim of the present study was to associate PhA with sarcopenia and its components in kidney transplantation patients. Read More

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http://dx.doi.org/10.1053/j.jrn.2018.10.005DOI Listing
May 2019
1 Read

Comparison of the Correlates Between Body Mass Index, Waist Circumference, Waist-to-Height Ratio, and Chronic Kidney Disease in a Rural Chinese Adult Population.

J Ren Nutr 2018 Dec 20. Epub 2018 Dec 20.

Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China. Electronic address:

Objective: The aim of the article was to evaluate and compare the correlates of body mass index (BMI), waist circumference (WC), and waist-to-height ratio (WHtR) with chronic kidney disease (CKD) among a rural Chinese adult population.

Design: This was a case-control study.

Methods: A total of 4,221 adults, aged 27 to 95 years, were divided into different groups based on the standard of CKD stages. Read More

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http://dx.doi.org/10.1053/j.jrn.2018.10.008DOI Listing
December 2018
4 Reads

Bicarbonate Supplement Restores Urinary Klotho Excretion in Chronic Kidney Disease: A Pilot Study.

J Ren Nutr 2018 Dec 20. Epub 2018 Dec 20.

Univ Lyon, UCBL, CARMEN, CENS, Département de Néphrologie-Dialyse-Nutrition, Centre Hospitalier Lyon-Sud, Pierre Bénite, France. Electronic address:

Objective: We tested the hypothesis that correcting acidosis may improve urinary Klotho excretion and serum α-Klotho.

Design: This is a prospective, interventional, nonrandomized, open-label trial study. In this study setting, metabolic acidosis is commonly observed during chronic kidney disease (CKD). Read More

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http://dx.doi.org/10.1053/j.jrn.2018.11.001DOI Listing
December 2018
3 Reads

The Likelihood of Self-reporting Balance Problems in Those With Advanced Chronic Kidney Disease, Slow Gait Speed, or Low Vitamin D.

J Ren Nutr 2018 Dec 20. Epub 2018 Dec 20.

Department of Biomechanics, University of Nebraska at Omaha, Omaha, Nebraska. Electronic address:

Objective: The purpose of this study was to determine the prevalence of vitamin D (25(OH)D) and balance deficits in persons with chronic kidney disease (CKD) and the likelihood of self-reporting balance and falling problems, measured gait speed in persons with kidney disease, and low levels of vitamin D and albumin.

Design: Analysis of the National Health and Nutrition Examination Survey 1999-2004 data set.

Subjects: The study included 8,554 subjects aged >40 years who were categorized into CKD stages based on the glomerular filtration rate (normal kidney function and stages 1 and 2 served as the control group, and stages 3 and 4/5 served as the CKD groups). Read More

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http://dx.doi.org/10.1053/j.jrn.2018.10.011DOI Listing
December 2018
1 Read

Low-Carbohydrate High-Protein Diet is Associated With Increased Risk of Incident Chronic Kidney Diseases Among Tehranian Adults.

J Ren Nutr 2018 Dec 19. Epub 2018 Dec 19.

Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, I.R. Iran.

Objective: The aim of this article was to assess the association between low-carbohydrate high-protein (LCHP) diet score and the risk of incident chronic kidney disease (CKD).

Design And Methods: This cohort study was conducted on 1,797 Iranian participants, aged ≥20 years, followed-up for a mean of 6.1 years. Read More

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http://dx.doi.org/10.1053/j.jrn.2018.10.007DOI Listing
December 2018
1 Read
2.548 Impact Factor

Potassium Additives and Bioavailability: Are We Missing Something in Hyperkalemia Management?

Authors:
Kelly Picard

J Ren Nutr 2018 Dec 19. Epub 2018 Dec 19.

Northern Alberta Renal Program, Alberta Health Services, Edmonton, Alberta. Electronic address:

Hyperkalemia and hyperphosphatemia are common metabolic disturbances in chronic kidney disease. Management may include instructions on a low-potassium or low-phosphorus diet, respectively. Low-phosphorus diet teaching includes information on phosphorus additives in addition to naturally occurring phosphorus food sources. Read More

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http://dx.doi.org/10.1053/j.jrn.2018.10.003DOI Listing
December 2018
4 Reads

Determinants and the Role of Self-Efficacy in a Sodium-Reduction Trial in Hemodialysis Patients.

J Ren Nutr 2018 Dec 19. Epub 2018 Dec 19.

New York University School of Medicine, Center for Healthful Behavior Change, New York, New York.

Objective: This study was to assess the impact of baseline dietary self-efficacy on the effect of a dietary intervention to reduce sodium intake in patients undergoing hemodialysis (HD) and to identify determinants of low dietary self-efficacy.

Methods: This is a post hoc analysis of the BalanceWise study, a randomized controlled trial that aimed to reduce dietary sodium intake in HD patients recruited from 17 dialysis centers in Pennsylvania. The main outcome measures include dietary self-efficacy and reported dietary sodium density. Read More

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http://dx.doi.org/10.1053/j.jrn.2018.10.006DOI Listing
December 2018
1 Read

Obesity and Mortality in End-Stage Renal Disease. Is It Time to Reverse the "Reverse Epidemiology"-at Least in Peritoneal Dialysis?

J Ren Nutr 2018 Nov 15. Epub 2018 Nov 15.

Kaiser Permanente Southern California, Department of Research & Evaluation, Pasadena, California.

With the rising incidence of chronic kidney disease, there has been a steady growth of the hemodialysis (HD) and peritoneal dialysis (PD) population. Prevalence of obesity has also been on the rise. It has been proposed by some that obesity helps with survival in HD and possibly in PD patients-a concept called "Reverse Epidemiology. Read More

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http://dx.doi.org/10.1053/j.jrn.2018.09.005DOI Listing
November 2018
2 Reads

Glycemic Status and Mortality in Chronic Kidney Disease According to Transition Versus Nontransition to Dialysis.

J Ren Nutr 2019 Mar 15;29(2):82-90. Epub 2018 Nov 15.

Harold Simmons Center for Chronic Disease Research and Epidemiology, University of California Irvine School of Medicine, Orange, California; Tibor Rubin Veterans Affairs Medical Center, Long Beach, California.

Objective: The impact of glycemic control in diabetic patients with chronic kidney disease (CKD) who may or may not transition to dialysis remains uncertain, given recent interest in the conservative management of advanced CKD without dialysis therapy, which may benefit from alternative glycemic control strategies.

Design And Methods: Among a national cohort of US Veterans, we examined the association of glycemic status, defined by averaged random blood glucose and hemoglobin A1c (HbA1c), with mortality after transitioning to dialysis over 2007-2011 (Transition Cohort) compared with patients in a one-to-one matched cohort of CKD patients with diabetes who did not transition to dialysis (Nontransition Cohort).

Results: Among 17,121 patients in the Transition Cohort, averaged random glucose ≥200 mg/dL was associated with higher mortality in expanded case-mix analyses (reference: 100-<120 mg/dL): adjusted hazard ratio (95% confidence interval) 1. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10512276183017
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http://dx.doi.org/10.1053/j.jrn.2018.07.003DOI Listing
March 2019
20 Reads
2.548 Impact Factor

Bioelectrical Impedance Analysis-Derived Phase Angle Predicts Protein-Energy Wasting in Maintenance Hemodialysis Patients.

J Ren Nutr 2018 Nov 13. Epub 2018 Nov 13.

Department of Nutrition, School of Public Health, Sun Yat-Sen University, Guangzhou, China.

Objective(s): To explore the validity of using bioelectrical impedance analysis (BIA)-derived 50 kHz phase angle (PhA) in predicting protein-energy wasting (PEW) in Chinese maintenance hemodialysis (MHD) patients.

Design And Methods: The design was a cross-sectional study. A total of 173 of MHD patients and 173 healthy adults were enrolled in the study. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10512276183021
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http://dx.doi.org/10.1053/j.jrn.2018.09.001DOI Listing
November 2018
20 Reads