371,134 results match your criteria Journal of Primary Care & Community Health [Journal]


Prevalence of antibodies to lung self-antigens (Kα1 tubulin and collagen V) and donor specific antibodies to HLA in lung transplant recipients and implications for lung transplant outcomes: Single center experience.

Transpl Immunol 2019 Feb 19. Epub 2019 Feb 19.

Division of Pulmonary and Critical Care Medicine, University of Texas Southwestern Medical Center, Dallas, TX, United States. Electronic address:

Purpose: For patients with end stage lung disease, lung transplantation (LT) remains the only definitive treatment option. Long term survival post LT is limited by acute and chronic allograft dysfunction. Antibodies to lung self-antigens Kα1Tubulin and collagen V (autoantibodies) have been implicated in adverse outcomes post LT. Read More

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http://dx.doi.org/10.1016/j.trim.2019.02.006DOI Listing
February 2019

The Stability of Treatment Preferences among Patients with Advanced Cancer.

J Pain Symptom Manage 2019 Feb 19. Epub 2019 Feb 19.

Cornell Center for Research on End-of-Life Care, Weill Cornell Medicine, New York, New York, U.S.A.; Division of Geriatrics and Palliative Medicine, Department of Medicine, Weill Cornell Medicine, New York, New York, U.S.A.. Electronic address:

Context: Stability of patients' treatment preferences has important implications for decisions about concurrent and future treatment.

Objectives: To examine the stability of treatment preferences and correlates among patients with advanced cancer.

Methods: In this cohort, 104 patients with metastatic cancer, progression after at least one chemotherapy regimen and an oncologist-estimated life-expectancy of ≤ six months participated in structured interviews following clinical visits in which patients' recent scans were discussed. Read More

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http://dx.doi.org/10.1016/j.jpainsymman.2019.01.016DOI Listing
February 2019

Autologous Transplantation for Male Germ Cell Tumors: Improved Outcomes over 3 decades.

Biol Blood Marrow Transplant 2019 Feb 19. Epub 2019 Feb 19.

Medical College of Wisconsin, Milwaukee, WI.

Purpose: The curative potential of autologous hematopoietic cell transplantation (autoHCT) for male germ cell tumors (GCT) is well established. Optimal timing and number (single, ST vs. tandem, TT vs. Read More

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http://dx.doi.org/10.1016/j.bbmt.2019.02.015DOI Listing
February 2019

The Incomplete Medicalization of Obesity: Physician Office Visits, Diagnoses, and Treatments, 1996-2014.

Public Health Rep 2019 Feb 22:33354918813102. Epub 2019 Feb 22.

2 Department of Sociology, University of Kentucky, Lexington, KY, USA.

Objectives:: Despite increased awareness of obesity-related health risks and myriad treatment options, obesity still affects more than one-third of persons in the United States and is a substantial public health problem. Studies show that physicians play a key role in obesity prevention and treatment. The objective of this study was to examine the extent to which obesity is diagnosed and treated at the level of patient-physician interaction. Read More

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http://dx.doi.org/10.1177/0033354918813102DOI Listing
February 2019

AMEE guide no. 123 - How to read studies of educational costs.

Med Teach 2019 Feb 22:1-8. Epub 2019 Feb 22.

j BMJ Learning and Quality , London , United Kingdom of Great Britain and Northern Ireland.

Healthcare and health professions education share many of the same problems in decision making. In both cases, there is a finite amount of resources, and so choices need to be made between alternatives. To navigate the options available requires effective decision making. Read More

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http://dx.doi.org/10.1080/0142159X.2018.1552784DOI Listing
February 2019

Association between otitis media infection and failed hearing screenings in children.

PLoS One 2019 22;14(2):e0212777. Epub 2019 Feb 22.

Department of Pediatrics, State University of New York Downstate Medical Center, Brooklyn, New York, United States of America.

This study aims to assess prospectively whether there is an association between frequencies of upper respiratory tract infections (URTI) or asthma in early childhood and failed otoacoustic emission (OAE) screenings later in life. There are no clear recommendations for hearing testing following acute otitis media (AOM) infection. This is a retrospective, practice based chart review. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212777PLOS
February 2019

Effective coverage of essential antenatal care interventions: A cross-sectional study of public primary healthcare clinics in the West Bank.

PLoS One 2019 22;14(2):e0212635. Epub 2019 Feb 22.

Global Health Cluster, Division for Health Services, Norwegian Institute of Public Health, Oslo, Norway.

Background: The proportion of women attending four or more antenatal care (ANC) visits is widely used for monitoring, but provides limited information on quality of care. Effective coverage metrics, assessing if ANC interventions are completely delivered, can identify critical gaps in healthcare service delivery. We aimed to measure coverage of at least one screening and effective coverage of ANC interventions in the public health system in the West Bank, Palestine, and to explore associations between infrastructure-related and maternal sociodemographic variables and effective coverage. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212635PLOS
February 2019

Simplified end stage renal failure risk prediction model for the low-risk general population with chronic kidney disease.

PLoS One 2019 22;14(2):e0212590. Epub 2019 Feb 22.

Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.

Background: Chronic kidney disease (CKD) contributes significant morbidity and mortality among Asians; hence interventions should focus on those most at-risk of progression. However, current end stage renal failure (ESRF) risk stratification tools are complex and not validated in multi-ethnic Asians. We hence aimed to develop an ESRF risk prediction model by taking into account ethnic differences within a fairly homogenous socioeconomic setting and using parameters readily accessible to primary care clinicians managing the vast majority of patients with CKD. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212590PLOS
February 2019

Using natural language processing and machine learning to classify health literacy from secure messages: The ECLIPPSE study.

PLoS One 2019 22;14(2):e0212488. Epub 2019 Feb 22.

UCSF Center for Vulnerable Populations, Department of Medicine, University of California, San Francisco, California, United States of America.

Limited health literacy is a barrier to optimal healthcare delivery and outcomes. Current measures requiring patients to self-report limitations are time-consuming and may be considered intrusive by some. This makes widespread classification of patient health literacy challenging. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212488PLOS
February 2019

Palliative Care Comes of Age in the 2018 Declaration of Astana.

J Palliat Med 2019 Mar;22(3):242

1 International Association for Hospice and Palliative Care, Houston, Texas.

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http://dx.doi.org/10.1089/jpm.2018.0615DOI Listing

Assessment of Changes in the Geographical Distribution of Opioid-Related Mortality Across the United States by Opioid Type, 1999-2016.

JAMA Netw Open 2019 Feb 1;2(2):e190040. Epub 2019 Feb 1.

Department of Statistical Sciences, University of Toronto, Toronto, Ontario, Canada.

Importance: As the opioid epidemic evolves, it is vital to identify changes in the geographical distribution of opioid-related deaths, and the specific opioids to which those deaths are attributed, to ensure that federal and state public health interventions remain appropriately targeted.

Objective: To identify changes in the geographical distribution of opioid-related mortality across the United States by opioid type.

Design, Setting, And Participants: Cross-sectional study using joinpoint modeling and life table analysis of individual-level data from the National Center for Health Statistics on 351 630 US residents who died from opioid-related causes from January 1, 1999, to December 31, 2016, for all of the United States and the District of Columbia. Read More

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http://dx.doi.org/10.1001/jamanetworkopen.2019.0040DOI Listing
February 2019

Effectiveness of Later-Stage Exercise Programs vs Usual Medical Care on Physical Function and Activity After Total Knee Replacement: A Randomized Clinical Trial.

JAMA Netw Open 2019 Feb 1;2(2):e190018. Epub 2019 Feb 1.

Department of Physical Therapy, University of Pittsburgh, Pittsburgh, Pennsylvania.

Importance: Several functional limitations persist after total knee replacement (TKR). Intensive exercise programs could resolve these limitations but are not well tolerated by many patients until a later stage (>2 months) after surgery. Evidence for exercise at a later stage after TKR is limited. Read More

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http://dx.doi.org/10.1001/jamanetworkopen.2019.0018DOI Listing
February 2019

Should we provide outreach rehabilitation to very old people living in Nursing Care Facilities after a hip fracture? A randomised controlled trial.

Age Ageing 2019 Feb 22. Epub 2019 Feb 22.

Health and Social Care Economics Group, Flinders University, Sturt Road, Bedford Park SA, Australia.

Objective: to determine whether a 4-week postoperative rehabilitation program delivered in Nursing Care Facilities (NCFs) would improve quality of life and mobility compared with receiving usual care.

Design: parallel randomised controlled trial with integrated health economic study.

Setting: NCFs, in Adelaide South Australia. Read More

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http://dx.doi.org/10.1093/ageing/afz005DOI Listing
February 2019

Does an Elastic Compression Bandage Provide Any Benefit After Primary TKA?

Clin Orthop Relat Res 2019 Jan;477(1):134-144

The Rothman Institute of Orthopedics at Thomas Jefferson University, Philadelphia, PA, USA.

Background: Compression bandages often are used after TKA to reduce swelling. However, the degree to which they are helpful has not been well characterized.

Questions/purposes: The purpose of this study was to determine whether use of a compression bandage after TKA was associated with (1) less leg swelling (our primary endpoint); or (2) secondary study endpoints, including improved ROM of flexion and extension, lower visual analog scale (VAS) pain scores for worst pain and pain during physical therapy just before surgery, postoperative day (POD) 1, POD 2, and POD 28, or fewer wound complications within 90 days of surgery. Read More

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http://dx.doi.org/10.1097/CORR.0000000000000459DOI Listing
January 2019

The 2018 Chitranjan S. Ranawat, MD Award: Developing and Implementing a Novel Institutional Guideline Strategy Reduced Postoperative Opioid Prescribing After TKA and THA.

Clin Orthop Relat Res 2019 Jan;477(1):104-113

C. C. Wyles, M. Hevesi, R. T. Trousdale, M. W. Pagnano, T. M. Mabry Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA E. R. Trousdale, H. M. Gazelka Department of Anesthesiology, Mayo Clinic, Rochester, MN, USA D. S. Ubl, E. B. Habermann Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery Surgical Outcomes Program, Mayo Clinic, Rochester, MN, USA.

Background: Opioid prescription management is challenging for orthopaedic surgeons, and we lack evidence-based guidelines for responsible opioid prescribing. Our institution recently developed opioid prescription guidelines for patients undergoing several common orthopaedic procedures including TKA and THA in an effort to reduce and standardize prescribing patterns.

Questions/purposes: (1) How do opioid prescriptions at discharge and 30-day refill rates change in opioid-naïve patients undergoing primary TKA and THA before and after implementation of a novel prescribing guideline strategy? (2) What patient, surgical, and in-hospital factors influence opioid prescription quantity and refill rate?

Methods: New institutional guidelines for patients undergoing TKA and THA recommend a maximum postoperative prescription of 400 oral morphine equivalents (OME), comparable to 50 tablets of 5 mg oxycodone or 80 tablets of 50 mg tramadol. Read More

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http://dx.doi.org/10.1007/s11999.0000000000000292DOI Listing
January 2019

2018 John N. Insall Award: Recovery of Knee Flexion With Unsupervised Home Exercise Is Not Inferior to Outpatient Physical Therapy After TKA: A Randomized Trial.

Clin Orthop Relat Res 2019 Jan;477(1):60-69

The Rothman Institute at Thomas Jefferson University, Philadelphia, PA, USA.

Background: Concerns about the cost and convenience of postsurgical physical therapy (PT) have sparked interest in unsupervised, home-based rehabilitation. However, the effectiveness of unsupervised home exercise after primary TKA has not been previously evaluated.

Questions/purposes: (1) Can unsupervised home exercise after surgery provide noninferior recovery of passive knee flexion compared with formal outpatient PT? (2) Does a web-based platform for home-based exercise provide an advantage compared with a printed PT manual?

Methods: We conducted a randomized, noninferiority trial involving 290 patients (20% of the 1464 eligible patients who could be contacted) who underwent primary TKA from March 2016 to April 2018. Read More

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http://dx.doi.org/10.1097/CORR.0000000000000561DOI Listing
January 2019

Higher Volume Surgeons Have Lower Medicare Payments, Readmissions, and Mortality After THA.

Clin Orthop Relat Res 2019 Feb;477(2):334-341

W. S. Murphy, Harvard Medical School, Harvard Business School, Boston, MA, USA T. Cheng, B. Lin, D. Terry, Archway Health Advisors LLC, Watertown, MA, USA S. B. Murphy, New England Baptist Hospital, Tufts University School of Medicine, Boston, MA, USA.

Background: The advent of value-based care, in which surgeons and hospitals accept more responsibility for clinical and financial results, has increased the focus on surgeon- and hospital-specific outcomes. However, methods to identify high-quality, low-cost surgeons are not well developed.

Questions/purposes: (1) Is there an association between surgeon THA volume and 90-day Centers for Medicare & Medicaid Services (CMS) Part A payments, readmissions, or mortality? (2) What proportion of THAs in the United States is performed by low- and high-volume surgeons?

Methods: We performed a retrospective analysis of the CMS Limited Data Set on all primary elective THAs performed in the United States (except Maryland) between January 2013 and June 2016 on patients insured by Medicare. Read More

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http://dx.doi.org/10.1097/CORR.0000000000000370DOI Listing
February 2019

Increasing Mobility via In-hospital Ambulation Protocol Delivered by Mobility Technicians: A Pilot Randomized Controlled Trial.

J Hosp Med 2019 Feb 20;14:E1-E6. Epub 2019 Feb 20.

Center for Value-Based Care Research, Medicine Institute, Cleveland Clinic, Cleveland, Ohio.

Background: Ambulating medical inpatients may improve outcomes, but this practice is often overlooked by nurses who have competing clinical duties.

Objective: This study aimed to assess the feasibility and effectiveness of dedicated mobility technician-assisted ambulation in older inpatients.

Design: This study was a single-blind randomized controlled trial. Read More

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http://dx.doi.org/10.12788/jhm.3153DOI Listing
February 2019

Care Transitions Program for High-Risk Frail Older Adults is Most Beneficial for Patients with Cognitive Impairment.

J Hosp Med 2019 Feb 20;14:E1-E8. Epub 2019 Feb 20.

Division of Primary Care Internal Medicine, Mayo Clinic, Rochester, Minnesota.

Background: Although posthospitalization care transitions programs (CTP) are highly diverse, their overall program thoroughness is most predictive of their success.

Objective: To identify components of a successful homebased CTP and patient characteristics that are most predictive of reduced 30-day readmissions.

Design: Retrospective cohort. Read More

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http://dx.doi.org/10.12788/jhm.3112DOI Listing
February 2019

European primary care research and a national general practice research agenda.

Authors:
Jelle Stoffers

Eur J Gen Pract 2019 Jan;25(1):3-4

a Department of Family Medicine , Care and Public Health Research Institute (CAPHRI), Maastricht University , Maastricht , The Netherlands.

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http://dx.doi.org/10.1080/13814788.2018.1559568DOI Listing
January 2019

Exploring the real-world profile of refractory and non-refractory chronic idiopathic urticaria in the USA: clinical burden and healthcare resource use.

Curr Med Res Opin 2019 Feb 22. Epub 2019 Feb 22.

b Health Economics and Outcomes Research, Novartis Pharmaceuticals Corporation , East Hanover , NJ , USA.

Introduction: Chronic idiopathic/spontaneous urticaria (CIU/CSU) is a debilitating skin condition that is burdensome for patients and healthcare providers. We aimed to describe clinical characteristics, consultation patterns, and healthcare resource utilization in real-world US patients with refractory and non-refractory CIU/CSU.

Methods: Data were collected from the Adelphi Real World 2015 Urticaria Disease Specific Programme. Read More

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http://dx.doi.org/10.1080/03007995.2019.1586222DOI Listing
February 2019

Distal Ureter Management during Nephroureterectomy: Evidence from a Systematic Review and Cumulative Analysis.

J Endourol 2019 Feb 22. Epub 2019 Feb 22.

Queen Elizabeth University Hospital, 473300, Glasgow Urological Research Unit, Glasgow, United Kingdom of Great Britain and Northern Ireland ;

Introduction & Objectives: Standard of care in upper tract urothelial cancer is nephroureterectomy with bladder cuff excision (BCE). However, alternative techniques such as transurethral incision/resection have been employed to simplify distal ureterectomy. The optimum strategy is unclear and current guidelines do not specify a gold standard technique. Read More

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http://dx.doi.org/10.1089/end.2018.0819DOI Listing
February 2019

A membership categorization analysis of roles, activities and relationships in inclusive research conducted by co-researchers with intellectual disabilities.

J Appl Res Intellect Disabil 2019 Feb 22. Epub 2019 Feb 22.

Chair Disability Studies: Diversity in Participation, Rotterdam University of Applied Sciences, Rotterdam, The Netherlands.

Background: Inclusive research is studied mainly in short-term collaborations between researchers with and without intellectual disabilities focusing on practicalities. Structural study of long-term collaborations can provide insight into different roles of inclusive researchers, thereby contributing to a collective approach.

Method: Interviews with inclusive research team members (n = 3), colleagues (n = 8), and managers (n = 2) and three group discussions within the inclusive research team were held. Read More

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http://dx.doi.org/10.1111/jar.12567DOI Listing
February 2019

Prevalence, distribution, and clinical characteristics of hemangiosarcoma-associated skeletal muscle metastases in 61 dogs: A whole body computed tomographic study.

J Vet Intern Med 2019 Feb 22. Epub 2019 Feb 22.

Service of Diagnostic Imaging, I Portoni Rossi Veterinary Hospital, Zola Predosa, Bologna, Italy.

Background: Skeletal muscle metastases (SMMs) have been described sporadically in canine oncology.

Hypothesis/objectives: To determine the prevalence, localization, and clinical signs of SMMs associated with hemangiosarcoma (HSA) in a population of dogs presented for whole body computed tomography (CT).

Animals: Dogs with a histologically confirmed HSA and a tissue core specimen or fine needle aspirate of suspected metastatic lesions were included in the study. Read More

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http://dx.doi.org/10.1111/jvim.15456DOI Listing
February 2019

Perspectives of beneficiaries, health service providers, and community members on a maternal and child health conditional cash transfer pilot programme in Nigeria.

Int J Health Plann Manage 2019 Feb 22. Epub 2019 Feb 22.

SURE-P MCH Project Implementation Unit, National Primary Health Care Development Agency, Abuja, Nigeria.

Background: Our paper presents experiences and perceptions of beneficiaries, health service providers, and community members about a conditional cash transfer (CCT) programme piloted in Nigeria from April 2013 to May 2015 to boost demand for maternal, newborn, and child health services.

Methods: We conducted a descriptive cross-sectional retrospective study using both qualitative and quantitative methods. Personal interviews and focus group discussions (FGDs) were conducted between June and July 2015 for 314 CCT beneficiaries, 72 ward development committee (WDC) members, and 60 service providers (midwives, community health extension workers [CHEWs], and village health workers [VHWs]) including 29 officers-in-charge as key informants. Read More

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http://dx.doi.org/10.1002/hpm.2741DOI Listing
February 2019

Reducing arthritis fatigue impact: two-year randomised controlled trial of cognitive behavioural approaches by rheumatology teams (RAFT).

Ann Rheum Dis 2019 Feb 6. Epub 2019 Feb 6.

Department of Health and Social Sciences, University of the West of England Bristol, Bristol, UK.

Objectives: To see if a group course delivered by rheumatology teams using cognitive-behavioural approaches, plus usual care, reduced RA fatigue impact more than usual care alone.

Methods: Multicentre, 2-year randomised controlled trial in RA adults (fatigue severity6/10, no recent major medication changes). RAFT (Reducing Arthritis Fatigue: clinical Teams using CB approaches) comprises seven sessions, codelivered by pairs of trained rheumatology occupational therapists/nurses. Read More

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http://dx.doi.org/10.1136/annrheumdis-2018-214469DOI Listing
February 2019

Effect of Supportive Supervision on Performance of Malaria Rapid Diagnostic Tests in Sub-Saharan Africa.

Am J Trop Med Hyg 2019 Feb 19. Epub 2019 Feb 19.

President's Malaria Initiative (PMI) MalariaCare Project, PATH, Washington, District of Columbia.

Rapid diagnostic tests (RDTs) are one of the primary tools used for parasitological confirmation of suspected cases of malaria. To ensure accurate results, health-care workers (HCWs) must conduct the RDT test correctly. Trained supervisors visited 3,603 facilities to assess RDT testing performance and conduct outreach training and supportive supervision activities in eight African countries between 2015 and 2017, using a 12-point checklist to determine if key steps were being performed. Read More

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http://dx.doi.org/10.4269/ajtmh.18-0364DOI Listing
February 2019

Social and economic influences on infant and child feeding practices in a Marshallese community.

Public Health Nutr 2019 Feb 22:1-10. Epub 2019 Feb 22.

1Office of Community Health and Research,University of Arkansas for Medical Sciences,Northwest Campus,1125 N. College Avenue,Fayetteville,AR 72701,USA.

Objective: The present study aimed to examine the key influences on infant and child feeding practices among a Marshallese community at each social ecological level. It is the first study to examine the key influences on infant and child feeding practices with Marshallese immigrant women in the USA and helps fill a gap in the previous literature that has included other immigrant women.

Design: Community-based participatory research design with twenty-seven participants taking part in four qualitative focus groups. Read More

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http://dx.doi.org/10.1017/S1368980018004007DOI Listing
February 2019

Systems biology identifies preserved integrity but impaired metabolism of mitochondria due to a glycolytic defect in Alzheimer's disease neurons.

Aging Cell 2019 Feb 21:e12924. Epub 2019 Feb 21.

Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.

Mitochondrial dysfunction is implicated in most neurodegenerative diseases, including Alzheimer's disease (AD). We here combined experimental and computational approaches to investigate mitochondrial health and bioenergetic function in neurons from a double transgenic animal model of AD (PS2APP/B6.152H). Read More

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http://dx.doi.org/10.1111/acel.12924DOI Listing
February 2019

The heart rate variability derived Newborn Infant Parasympathetic Evaluation (NIPE ) Index in paediatric surgical patients from 0-2 years under sevoflurane anaesthesia - a prospective observational pilot study.

Paediatr Anaesth 2019 Feb 21. Epub 2019 Feb 21.

Department of Anaesthesiology, Erasmus University Medical Center, Sophia Children's Hospital, Rotterdam, The Netherlands.

Background: The heart rate variability derived Newborn Infant Parasympathetic Evaluation (NIPE ) Index is a continuous non-invasive tool to assess pain and discomfort in infants < 2 years. Initial studies focused on pain monitoring in the neonatal intensive care unit environment.

Aim: To investigate the performance of the NIPE in infants under sevoflurane anaesthesia. Read More

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http://dx.doi.org/10.1111/pan.13613DOI Listing
February 2019

Oral Care Practices in Non-Mechanically Ventilated Intensive Care Unit Patients: An Integrative Review.

J Clin Nurs 2019 Feb 21. Epub 2019 Feb 21.

University of Central Florida, 3205 Portofino Point Apt. B-1, Coconut Creek, FL, 33066-1223.

Aims And Objectives: The primary aim of this integrative review was to explore current oral care practices in non-mechanically ventilated ICU patients.

Background: Oral hygiene is an important aspect of nursing care in hospitalized populations. Oral care is a disease preventive and cost-effective measure for patients, particularly in ICU patients. Read More

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http://dx.doi.org/10.1111/jocn.14829DOI Listing
February 2019

Comparing Web-Based Video Interventions to Enhance University Student Willingness to Donate Organs: A Randomized Controlled Trial.

Clin Transplant 2019 Feb 21:e13506. Epub 2019 Feb 21.

Center for Reducing Health Disparities, MetroHealth Campus of Case Western Reserve University, Cleveland, Ohio.

Background: The efficacy of video interventions to increase organ donation willingness remains unclear.

Methods: 3-arm web-based randomized controlled trial involving 2261 students at 3 northeastern Ohio universities. Intervention students watched a live-action (n=755) or animated (n=753) donation video. Read More

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http://dx.doi.org/10.1111/ctr.13506DOI Listing
February 2019

Lung disease in STAT3-Hyper-IgE-Syndrome requires intense therapy.

Allergy 2019 Feb 21. Epub 2019 Feb 21.

Environmental Medicine, UNIKA-T, Technical University of Munich and HelmholtzZentrum Munich, Munich/Augsburg, Germany.

Background: Pulmonary complications are responsible for high morbidity and mortality rates in patients with the rare immunodeficiency disorder STAT3 hyper-IgE syndrome (STAT3-HIES). The aim of this study was to expand knowledge about lung disease in STAT3-HIES.

Methods: The course of pulmonary disease, radiological and histopathological interrelations, therapeutic management, and the outcome of 14 STAT3-HIES patients were assessed. Read More

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http://dx.doi.org/10.1111/all.13753DOI Listing
February 2019

A concept analysis of health literacy.

Nurs Forum 2019 Feb 21. Epub 2019 Feb 21.

Texas Tech University Health Sciences Center School of Nursing, Lubbock, Texas.

Aim: To propose a conceptual definition of health literacy incorporating system demands, burdens, and complexities that are a critical part of patients' level of health literacy.

Background: Health literacy is used frequently in health care and often is confused with patients' reading and comprehension levels.

Design: Walker and Avant's concept analysis method was used. Read More

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http://dx.doi.org/10.1111/nuf.12331DOI Listing
February 2019

[Developments in mental health care in Dutch general practices: an overview of recent studies].

Tijdschr Psychiatr 2019 ;61(2):126-134

Background: Dutch policy aims to strengthen mental health care in general practices, to keep health care affordable. Recently, a new function (mental health nurses) and a new referral model for patients with mental health problems were introduced.
AIM: To explore to what extent the volume of mental health care in Dutch general practices has increased and to what extent the content changed in the period 2010-2015. Read More

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January 2019

Risk factors affecting hospital stay among patients undergoing colon cancer surgery: a prospective cohort study.

Support Care Cancer 2019 Feb 22. Epub 2019 Feb 22.

Research Unit, Hospital Galdakao-Usansolo, B° Labeaga s/n, 48960, Galdakao, Biscay, Spain.

Purpose: To identify and validate risk factors that contribute to prolonged length of hospital stay (LOS) in patients undergoing resection for colorectal cancer.

Methods: This prospective cohort study included 1955 patients admitted to 22 hospitals for primary resection of colorectal cancer. Multivariate analyses were used to identify and validate risk factors, randomizing patients into a derivation and a validation cohort. Read More

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http://dx.doi.org/10.1007/s00520-019-04683-7DOI Listing
February 2019

Health Characteristics of the Wayuu Indigenous People.

Mil Med 2019 Feb 22. Epub 2019 Feb 22.

Naval Hospital Jacksonville, 2080 Child Street, Jacksonville, FL.

Introduction: The identified number of isolated populations with unique medical characteristics is growing. These populations are difficult to study. Civil-military humanitarian operations are part of our medical force readiness training, and are also a venue through which unique populations can be simultaneously served and evaluated. Read More

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http://dx.doi.org/10.1093/milmed/usz021DOI Listing
February 2019

Impact of Fire Arms Training in a Virtual Reality Environment on Occupational Performance (Marksmanship) in a Polytrauma Population.

Mil Med 2019 Feb 22. Epub 2019 Feb 22.

Center for the Intrepid, Department of Rehabilitation Medicine, Brooke Army Medical Center, 3551 Roger Brooke Drive, JBSA Fort Sam Houston, TX.

Introduction: Polytrauma, to include major limb amputation, in a military population presents unique rehabilitation challenges with the overarching goal of restoring function leading to the primary question, "Is this Service Member (SM) capable of returning to duty following rehabilitation?" The US military has a vested interest in maximizing injured SMs occupational performance to allow for return to duty. The purpose of this report is to describe marksmanship (shot grouping and weapon qualification) and return to duty outcomes following a course of VRE-based firearm training in a polytrauma patient population.

Methods: The medical records, stored in the Armed Forces Health Longitudinal Technology Application (AHLTA), of all patients who received rehabilitative care at the Center for the Intrepid (CFI) to include VRE-based firearms training between 01OCT2015 and 01AUG2016 were manually reviewed for inclusion. Read More

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http://dx.doi.org/10.1093/milmed/usz010DOI Listing
February 2019

Vitamin D for the Immune System in Cystic Fibrosis (DISC): a double-blind, multicenter, randomized, placebo-controlled clinical trial.

Am J Clin Nutr 2019 Feb 22. Epub 2019 Feb 22.

Division of Endocrinology, Metabolism and Lipids, Department of Medicine, Emory University School of Medicine, Atlanta, GA.

Background: Patients with cystic fibrosis (CF) have increased risk of vitamin D deficiency owing to fat malabsorption and other factors. Vitamin D deficiency has been associated with increased risk of pulmonary exacerbations of CF.

Objectives: The primary objective of this study was to examine the impact of a single high-dose bolus of vitamin D3 followed by maintenance treatment given to adults with CF during an acute pulmonary exacerbation on future recurrence of pulmonary exacerbations. Read More

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http://dx.doi.org/10.1093/ajcn/nqy291DOI Listing
February 2019

Smartphone problem-solving therapy to reduce fear of cancer recurrence among breast cancer survivors: an open single-arm pilot study.

Jpn J Clin Oncol 2019 Feb 22. Epub 2019 Feb 22.

Division of Psycho-Oncology and Palliative Care, Nagoya City University Hospital, Mizuho-cho, Mizuho-ku, Nagoya, Japan.

Objectives: The purpose of this study was to investigate a newly developed smartphone problem-solving therapy (PST) application's feasibility and preliminary effectiveness for reducing fear of cancer recurrence (FCR) among breast cancer survivors.

Methods: Female disease-free breast cancer survivors aged 20-49 years who were more than 6 months post-breast surgery participated in the study. The patients received the smartphone PST using an iPhone or iPad for 8 weeks. Read More

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http://dx.doi.org/10.1093/jjco/hyz005DOI Listing
February 2019

Effect of prehospital tourniquets on resuscitation in extremity arterial trauma.

Trauma Surg Acute Care Open 2019 24;4(1):e000267. Epub 2019 Jan 24.

Department of Surgery, UNLV School of Medicine, Las Vegas, Nevada, USA.

Background: Timely tourniquet placement may limit ongoing hemorrhage and reduce the need for blood products. This study evaluates if prehospital tourniquet application altered the initial transfusion needs in arterial injuries when compared with a non-tourniquet control group.

Methods: Extremity arterial injuries were queried from our level I trauma center registry from 2013 to 2017. Read More

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http://dx.doi.org/10.1136/tsaco-2018-000267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350723PMC
January 2019

Primary Care Provider Continuity Is Associated With Improved Preventive Service Ordering During Brief Visits for Acute Symptoms.

Health Serv Res Manag Epidemiol 2019 Jan-Dec;6:2333392819826262. Epub 2019 Feb 6.

Division of Primary Care Internal Medicine, Mayo Clinic, Rochester, MN, USA.

Background: If a patient presents for an acute care visit and sees their assigned primary care provider (PCP), they may be more likely to receive preventive and other services than a patient not seeing their assigned PCP.

Methods: After exclusion of 2 visits with insufficient information, we reviewed 98 consecutive, outpatient internal medicine 15-minute acute care visits comparing patients seeing their assigned PCP with those seeing a non-PCP provider. The primary outcome, preventive service ordering, was measured in 2 ways: percentage of patient visits with preventive service ordered and the total number of preventive services ordered as a proportion of all preventive service items due for each entire cohort. Read More

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http://dx.doi.org/10.1177/2333392819826262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376498PMC
February 2019

Substance Use, Demographic and Socioeconomic Factors Are Independently Associated With Postpartum HIV Care Engagement in the Southern United States, 1999-2016.

Open Forum Infect Dis 2019 Feb 19;6(2):ofz023. Epub 2019 Jan 19.

Division of Epidemiology, Vanderbilt University Medical Center, Nashville, Tennessee.

Background: Retention in care (RIC) and viral suppression (VS) are associated with reduced HIV transmission and mortality. Studies addressing postpartum engagement in HIV care have been limited by small sample size, short follow-up, and a lack of data from the Southeast United States.

Methods: HIV-positive adult women with ≥1 prenatal visit at the Vanderbilt Obstetrics Comprehensive Care Clinic from 1999 to 2015 were included. Read More

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http://dx.doi.org/10.1093/ofid/ofz023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372056PMC
February 2019

Prevalence and Associated Factors of Depression among Patients with Diabetes at Jazan Province, Saudi Arabia: A Cross-Sectional Study.

Psychiatry J 2019 16;2019:6160927. Epub 2019 Jan 16.

Medical Resident, Internal Medicine Department, King Fahad Medical City, Riyadh, Saudi Arabia.

Context: Patients with diabetes mellitus (DM) have a poorer quality of life when compared with patients without DM. In fact, one in every five diabetic patients suffers from comorbid depression, which can lead to poor management, poor compliance with treatment, and low quality of life. Therefore, we assessed the prevalence of depression and identified its associated factors among diabetic patients at Jazan Province, KSA. Read More

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http://dx.doi.org/10.1155/2019/6160927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354152PMC
January 2019

Evaluating a childhood obesity program with the Reach, Effectiveness, Adoption, Implementation, Maintenance (RE-AIM) framework.

Prev Med Rep 2019 Mar 24;13:321-326. Epub 2019 Jan 24.

Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.

Primary care providers can use behavioral lifestyle interventions to effectively treat children with overweight and obesity, but implementing these interventions is challenging. Most childhood obesity intervention evaluation studies focus on effectiveness. Few studies describe implementation. Read More

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http://dx.doi.org/10.1016/j.pmedr.2019.01.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369326PMC

The impact of user charges on health outcomes in low-income and middle-income countries: a systematic review.

BMJ Glob Health 2018 10;3(Suppl 3):e001087. Epub 2019 Jan 10.

Public Health Policy Evaluation Unit, Department of Primary Care and Public Health, School of Public Health, Imperial College, London, UK.

Background: User charges are widely used health financing mechanisms in many health systems in low-income and middle-income countries (LMICs) due to insufficient public health spending on health. This study systematically reviews the evidence on the relationship between user charges and health outcomes in LMICs, and explores underlying mechanisms of this relationship.

Methods: Published studies were identified via electronic medical, public health, health services and economics databases from 1990 to September 2017. Read More

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http://dx.doi.org/10.1136/bmjgh-2018-001087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350744PMC
January 2019

Exercise-induced laryngeal obstruction in athletes treated with inspiratory muscle training.

BMJ Open Sport Exerc Med 2019 18;5(1):e000436. Epub 2019 Jan 18.

Department of Physiotherapy, Haukeland University Hospital, Bergen, Norway.

Background: Exercise-induced laryngeal obstruction (EILO) is common in athletes and presents with dyspnoea, chest tightness, inspiratory stridor and sometimes panic reactions. The evidence for conservative treatment is weak, but case reports suggest effects from inspiratory muscle training (IMT). We aimed to explore effects from IMT used in athletes with EILO. Read More

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http://dx.doi.org/10.1136/bmjsem-2018-000436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350751PMC
January 2019

Comparison of linezolid and daptomycin for the treatment of vancomycin-resistant enterococcal bacteremia.

Ther Adv Infect Dis 2019 Jan-Dec;6:2049936119828964. Epub 2019 Feb 13.

Division of Infectious Diseases, Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA.

Vancomycin-resistant enterococcal bacteremia (VRE-B) is a common nosocomial infection associated with significant morbidity and mortality. Daptomycin and linezolid are primary treatment options although definitive clinical data to assess comparative therapeutic effectiveness are lacking. This study assessed the outcomes of patients with VRE-B treated with linezolid or daptomycin. Read More

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http://dx.doi.org/10.1177/2049936119828964DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376491PMC
February 2019

Implementation of infection prevention and control in acute care hospitals in Mainland China - a systematic review.

Antimicrob Resist Infect Control 2019 11;8:32. Epub 2019 Feb 11.

Infection Control Program and WHO Collaborating Centre on Patient Safety, University of Geneva Hospitals and Faculty of Medicine, Rue Gabrielle Perret-Gentil 4, 1211 Geneva 14, Switzerland.

Background: Healthcare-associated infections (HAIs) and antimicrobial resistance (AMR) affect patients in acute-care hospitals worldwide. No systematic review has been published on adoption and implementation of the infection prevention and control (IPC) key components. The objective of this systematic review was to assess adoption and implementation of the three areas issued by the "National Health Commission of the People's Republic of China" in acute-care hospitals in Mainland China, and to compare the findings with the key and core components on effective IPC, issued by the European Centre for Disease Prevention and Control (ECDC) and the World Health Organization (WHO). Read More

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http://dx.doi.org/10.1186/s13756-019-0481-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371478PMC
February 2019

Opportunities for use of radiation therapy in penile cancer based on patterns of care in the United States from 2007 to 2013.

Ther Adv Urol 2019 Jan-Dec;11:1756287219828972. Epub 2019 Feb 8.

Department of Radiation Oncology, University of Kansas Medical Center, Kansas City, KS, USA.

Background: Radiation therapy (RT) is an effective modality for the treatment of squamous cell carcinomas of the penis. The National Comprehensive Cancer Network recommends consideration of primary radiation for penile preservation, in surgically unresectable tumors, and as adjuvant therapy for positive margins, bulky groin nodes or pelvic nodes. We performed a population-based analysis to evaluate the usage of RT in penile cancer from 2007 to 2013. Read More

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http://dx.doi.org/10.1177/1756287219828972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376511PMC
February 2019