3,643 results match your criteria Journal of Perinatal Medicine[Journal]


Association of maternal disease and medication use with the risk of congenital heart defects in offspring: a case-control study using logistic regression with a random-effects model.

J Perinat Med 2019 Feb 22. Epub 2019 Feb 22.

National Center for Birth Defect Monitoring, Department of Obstetrics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.

Objective To examine the association between maternal diseases and congenital heart defects (CHDs) and to evaluate whether those associations vary with corresponding medication use. Methods A multi-hospital case-control study conducted from February 2010 to December 2014 analysed 916 controls and 1236 cases. Participating mothers were asked whether they suffered from influenza, common cold, herpes and threatened abortion or had used corresponding medication during the periconception period or the early pregnancy period. Read More

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http://dx.doi.org/10.1515/jpm-2018-0281DOI Listing
February 2019

Erythropoietin in perinatal hypoxic-ischemic encephalopathy: a systematic review and meta-analysis.

J Perinat Med 2019 Feb 21. Epub 2019 Feb 21.

Department of Orthopedics, Bhimrao Ambedkar University, Agra, UP, India.

Background Erythropoietin (EPO) appears to confer neuroprotection to the injured brain. Randomized clinical trials (RCTs) have demonstrated its safety in neonates with hypoxic-ischemic encephalopathy (HIE); however, the evidence is unclear. The objective of this study was to examine the role of EPO in perinatal HIE by a systematic review and meta-analysis. Read More

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http://dx.doi.org/10.1515/jpm-2018-0360DOI Listing
February 2019

An exploratory study into social and healthcare variables of maternal mortality: a case-control study.

J Perinat Med 2019 Feb 21. Epub 2019 Feb 21.

Deputy of Health, Isfahan University of Medical Sciences, Isfahan, Iran.

Background Regarding the important role the mothers' health plays in shaping nations' well-being, this study endeavored to explore the main social and healthcare factors related to maternal mortality. Methods In this case-control study, data (viz., all maternal mortalities) were gathered from the national maternal mortality surveillance system. Read More

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http://dx.doi.org/10.1515/jpm-2018-0334DOI Listing
February 2019

Mesenchymal stromal cells and TGF-β1 in tracheal aspirate of premature infants: early predictors for bronchopulmonary dysplasia?

J Perinat Med 2019 Feb 21. Epub 2019 Feb 21.

Division of Neonatology, Department of Pediatrics, Cairo University Children's Hospital, Cairo, Egypt.

Background The pathogenesis of bronchopulmonary dysplasia (BPD) includes arrest of alveolar septation and enhanced fibrosis. We hypothesized that mesenchymal stromal cells (MSC) and transforming growth factor-β1 (TGF-β1) in tracheal aspirates of mechanically ventilated premature infants differ in BPD and non-BPD infants. Methods Tracheal aspirates were collected during the first week of life. Read More

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http://dx.doi.org/10.1515/jpm-2018-0305DOI Listing
February 2019

Neurological development may be accelerated in growth-restricted fetuses: a 4D ultrasound study.

J Perinat Med 2019 Feb 14. Epub 2019 Feb 14.

Department of Perinatology and Gynecology, Kagawa University Graduate School of Medicine, Miki, Kagawa, Japan.

Objective To assess whether neurological maturation and development are accelerated in fetal growth restriction (FGR) in utero using four-dimensional (4D) ultrasound. Methods The facial expressions of 50 appropriate-for-gestational-age (AGA) and 34 FGR fetuses aged between 28 and 35 gestational weeks were assessed using 4D ultrasound. Subsequently, they were differentiated into two gestational age groups (19 aged 28-31 weeks and 31 aged 32-35 weeks in AGA, and 15 aged 28-31 weeks and 19 aged 32-35 weeks in FGR). Read More

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http://dx.doi.org/10.1515/jpm-2018-0379DOI Listing
February 2019

A high concentration of fetal fibronectin in cervical secretions increases the risk of intra-amniotic infection and inflammation in patients with preterm labor and intact membranes.

J Perinat Med 2019 Feb 15. Epub 2019 Feb 15.

Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.

Objective To determine whether the risk of intra-amniotic infection/inflammation and spontaneous preterm delivery (SPTD) varies as a function of the concentration of cervical fetal fibronectin (fFN) in patients with preterm labor and intact membranes. Methods This prospective study included 180 patients with preterm labor and intact membranes who had a sample collected for quantitative fFN measurement and underwent amniocentesis. Amniotic fluid was cultured for aerobic and anaerobic bacteria and genital mycoplasmas. Read More

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http://dx.doi.org/10.1515/jpm-2018-0351DOI Listing
February 2019
1 Read

Reference range of fetal myocardial area by three-dimensional ultrasonography and its applicability in fetuses of pre-gestational diabetic women.

J Perinat Med 2019 Feb 14. Epub 2019 Feb 14.

Department of Obstetrics, Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP), São Paulo-SP, Brazil.

Objectives To determine the reference range for the myocardial area in healthy fetuses using three-dimensional (3D) ultrasonography and validate these results in fetuses of pregnant women with pre-gestational diabetes mellitus (DM). Methods This cross-sectional retrospective study included 168 healthy pregnant women between gestational weeks 20 and 33+6 days. The myocardial area was measured using spatio-temporal image correlation (STIC) in the four-chamber view. Read More

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http://dx.doi.org/10.1515/jpm-2018-0342DOI Listing
February 2019

Fetal abdominal cysts: antenatal course and postnatal outcomes.

J Perinat Med 2019 Feb 14. Epub 2019 Feb 14.

Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital, Imperial College Healthcare NHS Trust, London, UK.

Background There is little information on which to base the prognostic counselling as to whether an antenatally diagnosed fetal abdominal cyst will grow or shrink, or need surgery. This study aims to provide contemporary data on prenatally diagnosed fetal abdominal cysts in relation to their course and postnatal outcomes. Methods Fetal abdominal cysts diagnosed over 11 years in a single centre were identified. Read More

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http://dx.doi.org/10.1515/jpm-2018-0311DOI Listing
February 2019
1 Read

Twin anemia-polycythemia sequence and routine monitoring practices amongst maternal-fetal medicine specialists in the United States: an initial investigation.

J Perinat Med 2019 Feb 14. Epub 2019 Feb 14.

Kent State University, College of Public Health, Kent, OH, USA.

Background The purpose of this initial investigation was to begin to understand the routine twin anemia-polycythemia sequence (TAPS) monitoring practices of maternal-fetal medicine specialists (MFM specialists) in the United States in the absence of a formal guideline. Methods This study used an anonymous, online survey of 90 MFM specialists who were practicing in the United States. A $5 gift card to an online store was used to incentivize participants. Read More

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http://dx.doi.org/10.1515/jpm-2018-0240DOI Listing
February 2019

Behcet's disease and pregnancy: obstetrical and neonatal outcomes in a population-based cohort of 12 million births.

J Perinat Med 2019 Feb 15. Epub 2019 Feb 15.

Department of Obstetrics and Gynecology, Jewish General Hospital, McGill University, Montreal, Quebec, Canada.

Background Behcet's disease (BD) is a rare, multi-systemic inflammatory disorder for which only limited and contradictory data exists in the context of pregnancy. Our objective was to estimate the prevalence of BD in pregnancy and to evaluate maternal and fetal outcomes associated with pregnant women living with BD. Methods Using the 1999-2013 Healthcare Cost and Utilization Project-Nationwide Inpatient Sample from the United States, we performed a population-based retrospective cohort study consisting of pregnancies that occurred during this time period. Read More

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http://dx.doi.org/10.1515/jpm-2018-0161DOI Listing
February 2019
1 Read

Metabolic characterization of amniotic fluids of fetuses with enlarged nuchal translucency.

J Perinat Med 2019 Feb 13. Epub 2019 Feb 13.

Department of Prenatal and Preimplantation Genetic Diagnosis and Fetal Therapy, Ospedale Microcitemico, Via E. Jenner n/n, 09121 Cagliari, Italy.

Background In prenatal diagnosis, a thickened nuchal translucency (NT) is one of the most sensitive and specific markers for several defects but it may also be found in 5% of healthy fetuses. The pathophysiological causes that lead to an increase in NT are not yet fully understood. Metabolomics represents a new promising approach, useful for studying different metabolites in biological organisms in response to environmental stressors. Read More

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http://dx.doi.org/10.1515/jpm-2018-0314DOI Listing
February 2019
1 Read

Identification of growth patterns of preterm and small-for-gestational age children from birth to 4 years - do they catch up?

J Perinat Med 2019 Feb 13. Epub 2019 Feb 13.

Center for Medicine and Society, University of Freiburg, Freiburg, Germany.

Background A legitimate indication for growth hormone (GH) therapy in children born too light or short at birth [small-for-gestational age (SGA)] exists in Germany and the European Union only if special criteria are met. Methods We conducted a longitudinal, multi-centered study on full-term appropriate-for-gestational age (AGA, n=1496) and pre-term born SGA (n=173) and full-term SGA children (n=891) in Germany from 2006 to 2010. We analyzed height, weight, body mass index (BMI) and head circumference. Read More

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http://dx.doi.org/10.1515/jpm-2018-0239DOI Listing
February 2019

Associations between second-trimester amniotic fluid levels of ADAMTS4, ADAMTS5, IL-6, and TNF-α and spontaneous preterm delivery in singleton pregnancies.

J Perinat Med 2019 Feb 7. Epub 2019 Feb 7.

Faculty of Medicine, Department of Obstetrics and Gynecology, University of Koc, 34010 İstanbul, Turkey.

Background We investigated the roles of inflammatory cytokines and the A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) family in the etiopathogenesis of spontaneous preterm delivery by comparing the ADAMTS4, ADAMTS5, interleukin (IL)-6, and tumor necrosis factor-α (TNF-α) levels in second-trimester amniotic fluid between pregnant women with preterm birth and term controls. Methods All pregnant women who underwent second-trimester amniocentesis for genetic analysis between January 1, 2016, and January 1, 2018, were enrolled in this study. From this cohort, 22 patients who subsequently experienced spontaneous preterm delivery before 34 weeks of pregnancy formed the study group, and 22 age- and body mass index (BMI)-matched patients without preterm birth constituted the control group. Read More

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http://dx.doi.org/10.1515/jpm-2018-0297DOI Listing
February 2019
1 Read

Continuous infusion vs. intermittent flushing of peripheral cannulas in neonates using a needleless connector: a prospective cohort study.

J Perinat Med 2019 Feb 7. Epub 2019 Feb 7.

Neonatal Intensive Care Unit, Ghent University Hospital, Ghent, Belgium.

Objective To compare the duration of patency of peripheral intravenous cannulas between continuous infusion and intermittent flushing, while using a needleless intravenous connector in newborns admitted to the neonatal intensive care unit (NICU). Methods This is a prospective cohort study, including neonates admitted to the NICU who needed a peripheral intravenous cannula for intermittent administration of intravenous medication. In the first period, neonates received continuous peripheral infusion with NaCl 0. Read More

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http://dx.doi.org/10.1515/jpm-2018-0285DOI Listing
February 2019

Ultrasound Doppler waveform assessment: the story continues.

J Perinat Med 2019 Feb;47(2):139-141

Lenox Hill Hospital, Northwell Health, New York, NY, USA.

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http://dx.doi.org/10.1515/jpm-2018-0387DOI Listing
February 2019

Impact of the new guidelines on the management of premature rupture of membranes for the prevention of late preterm birth: an 11-year retrospective study.

J Perinat Med 2018 Dec 21. Epub 2018 Dec 21.

Obstetrics Service, Department of Obstetrics and Gynecology, Geneva University Hospitals, Geneva, Switzerland.

Objectives To evaluate the number of late preterm (LPT) births (between 34 0/7 and 36 6/7 weeks) that could have been prevented if expectant management of preterm premature rupture of membranes (PPROM) had been applied according to new recommendations. Methods A retrospective cohort study included all births at one Swiss center between January 1, 2002 and December 31, 2012. Births were categorized using an adapted evidence-based classification. Read More

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http://dx.doi.org/10.1515/jpm-2018-0324DOI Listing
December 2018
2 Reads

Prenatal diagnosis, associated findings and postnatal outcome of fetuses with double outlet right ventricle (DORV) in a single center.

J Perinat Med 2018 Dec 20. Epub 2018 Dec 20.

Department of Obstetrics and Prenatal Medicine, University of Bonn, Bonn, Germany.

Objective To assess the spectrum of associated anomalies, the intrauterine course, postnatal outcome and management of fetuses with double outlet right ventricle (DORV). Methods All cases of DORV diagnosed prenatally over a period of 8 years were retrospectively collected in a single tertiary referral center. All additional prenatal findings were assessed and correlated with the outcome. Read More

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http://dx.doi.org/10.1515/jpm-2018-0316DOI Listing
December 2018
1 Read

Dependencies between maternal and fetal autonomic tone.

J Perinat Med 2018 Dec 20. Epub 2018 Dec 20.

Biomagnetic Center, Hans Berger Department of Neurology, Jena University Hospital, Jena, Germany.

Background Disturbances in maternal physiology can cause changes in the fetal condition that may lead to impaired fetal development. Synchronous monitoring of cardiac autonomic tone via the assessment of the fetal and maternal heart rate (HR) and heart rate variability (HRV) may provide an appropriate diagnostic window. Methods Partial rank correlation coefficients between the maternal and fetal HR and HRV indices were calculated and verified by testing surrogate data in 315 magnetocardiographic (MCG) recordings from 141 healthy women pregnant with singleton fetuses [18+6 to 39+2 weeks gestational age (WGA)]. Read More

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http://dx.doi.org/10.1515/jpm-2018-0221DOI Listing
December 2018

Diabetes and obesity during pregnancy are associated with oxidative stress genotoxicity in newborns.

J Perinat Med 2018 Dec 18. Epub 2018 Dec 18.

Materno-Fetal Medicine Unit, Obstetrics and Gynecology Department, Hospital General de México Eduardo Liceaga O.D., Mexico City, Mexico.

Objective To compare the level of oxidative deoxyribonucleic acid (DNA) damage (genotoxicity) between the offspring of mothers with and without diabetes diagnosed during pregnancy and its association with maternal body mass index (BMI). Methods We measured 8-hydroxy-deoxyguanosine (8-OH-dG), a marker of DNA oxidative damage, in venous umbilical cord plasma from newborns of mothers with (n=34) and without (n=56) diabetes diagnoses obtained during pregnancy. Two markers of oxidative stress - namely, nitric oxide degradation products (NOx) and total glutathione (GSH) - were quantified in both mothers and newborns. Read More

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http://dx.doi.org/10.1515/jpm-2018-0201DOI Listing
December 2018

Customised birthweight standard for a Slovenian population.

J Perinat Med 2019 Jan 17. Epub 2019 Jan 17.

Perinatal Institute, Birmingham, B15 3BU, UK.

Objective To produce a customised birthweight standard for Slovenia. Methods This retrospective study used a cohort from the National Perinatal Information System of Slovenia (NPIS). Prospectively collected information from pregnancies delivered in all of Slovenia's 14 maternal hospitals between 1st January 2003 and 31st December 2012 was included. Read More

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http://dx.doi.org/10.1515/jpm-2018-0219DOI Listing
January 2019
1 Read

Therapeutic hypothermia during neonatal transport at Regional Perinatal Centers: active vs. passive cooling.

J Perinat Med 2018 Dec 7. Epub 2018 Dec 7.

Pediatrics, Division of Neonatology, New York University Medical Center, New York, NY, USA.

Background Earlier initiation of therapeutic hypothermia in term infants with hypoxic-ischemic encephalopathy has been shown to improve neurological outcomes. The objective of the study was to compare safety and effectiveness of servo-controlled active vs. passive cooling used during neonatal transport in achieving target core temperature. Read More

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http://dx.doi.org/10.1515/jpm-2018-0302DOI Listing
December 2018
3 Reads

Placental thickness on ultrasound and neonatal birthweight.

J Perinat Med 2018 Dec 3. Epub 2018 Dec 3.

Penn State Hershey Medical Center, Division of Maternal Fetal Medicine, Hershey, PA, USA.

Objective To investigate the relationship between maximal placental thickness during routine anatomy scan and birthweight at delivery. Methods This retrospective descriptive study analyzed 200 term, singleton deliveries in 2016 at Penn State Hershey Medical Center. We measured maximal placental thickness in the sagittal plane from the ultrasound images of the placenta obtained at the 18-21-week fetal anatomy screen. Read More

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http://dx.doi.org/10.1515/jpm-2018-0100DOI Listing
December 2018
1 Read

Stillbirths in women with pre-gravid obesity.

J Perinat Med 2018 Nov 29. Epub 2018 Nov 29.

Department of Obstetrics and Gynecology, Kaplan Medical Center, affiliated with the Hadassah-Hebrew University School of Medicine, Jerusalem, Rehovot, Israel.

Objective To determine the association between pre-gravid obesity and stillbirth. Methods A retrospective study of a population-based dataset of births at ≥34 weeks' gestation. We excluded fetal deaths due to lethal anomalies and intrapartum fetal deaths. Read More

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http://www.degruyter.com/view/j/jpme.ahead-of-print/jpm-2018
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http://dx.doi.org/10.1515/jpm-2018-0266DOI Listing
November 2018
9 Reads

Doppler evaluation of the fetal pulmonary artery pressure.

J Perinat Med 2019 Feb;47(2):218-221

Unidad de Diagnostico Perinatal (UDP)-Centro Policlínico Valencia (CPV), Valencia, Venezuela.

Background The Doppler effect has allowed the characterization of several vessels in maternal-fetal circulation that have been used for practical purposes. Our review of the literature showed a paucity of information about fetal pulmonary artery pressure (FMPAP) and its behavior in regard to gestational age (GA). The objectives of the study were to evaluate a formula to calculate the main FMPAP and its correlation with GA. Read More

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http://dx.doi.org/10.1515/jpm-2018-0112DOI Listing
February 2019

Fetal anomalies - From prenatal diagnosis to therapy.

J Perinat Med 2018 Nov;46(9):951-952

MD, FRCOG, FACOG, MBA, Professor of Obstetrics and Gynecology, Medical Director and CEO, University Medical Center Bonn, Sigmund-Freud-Strasse 25, 53105 Bonn, Germany, Tel.: +49 228.287-10900, Fax: +49 228.287-90 10900, Mobile: +49 151.58 233 667,

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http://dx.doi.org/10.1515/jpm-2018-0333DOI Listing
November 2018

Clinical chorioamnionitis at term IX: in vivo evidence of intra-amniotic inflammasome activation.

J Perinat Med 2018 Nov 9. Epub 2018 Nov 9.

Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI, USA.

Background The inflammasome has been implicated in the mechanisms that lead to spontaneous labor at term. However, whether the inflammasome is activated in the amniotic cavity of women with clinical chorioamnionitis at term is unknown. Herein, by measuring extracellular ASC [apoptosis-associated speck-like protein containing a C-terminal caspase recruitment domain (CARD)], we investigated whether there is in vivo inflammasome activation in amniotic fluid of patients with clinical chorioamnionitis at term with sterile intra-amniotic inflammation and in those with intra-amniotic infection. Read More

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http://www.degruyter.com/view/j/jpme.ahead-of-print/jpm-2018
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http://dx.doi.org/10.1515/jpm-2018-0271DOI Listing
November 2018
11 Reads
1.425 Impact Factor

Update on uterine tachysystole.

J Perinat Med 2019 Feb;47(2):152-160

Department of Obstetrics and Gynaecology, Mount Sinai Hospital, Toronto, ON, Canada.

Uterine tachysystole (TS) is a potentially significant intrapartum complication seen most commonly in induced or augmented labors but may also occur in women with spontaneous labor. When it occurs, maternal and perinatal complications can arise if not identified and managed promptly by obstetric care providers. Over recent years, new definitions of the condition have facilitated further research into the field, which has been synthesized to inform clinical management guidelines and protocols. Read More

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http://dx.doi.org/10.1515/jpm-2018-0175DOI Listing
February 2019
2 Reads

Antenatal magnesium sulfate for fetal neuroprotection: a critical appraisal and systematic review of clinical practice guidelines.

J Perinat Med 2018 Oct 20. Epub 2018 Oct 20.

Sidra Medicine, Department of OBGYN, Weill Cornell Medical College-Qatar, Qatar Foundation, PO Box 26999, Doha, Qatar.

Background Magnesium sulfate is an accepted intervention for fetal neuroprotection. There are some perceived differences in the international recommendations on the use magnesium sulfate for fetal neuroprotection in preterm labor. Content This systematic review analyses the available clinical guidelines for the use of magnesium sulfate for fetal neuroprotection and compares the recommendations, and assesses the quality of guidelines. Read More

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http://dx.doi.org/10.1515/jpm-2018-0174DOI Listing
October 2018
1 Read
1.430 Impact Factor

Small for gestational age and extremely low birth weight infant outcomes.

J Perinat Med 2019 Feb;47(2):247-251

MRC-Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, UK.

Background Small for gestational age (SGA) infants are less likely to develop respiratory distress syndrome (RDS), but more likely to develop bronchopulmonary dysplasia (BPD) and have a higher mortality. Our aim was to focus on outcomes of those with a birth weight less than or equal to 750 g. Methods The mortality, BPD severity, necrotising enterocolitis (NEC), home oxygen requirement and length of hospital stay were determined according to SGA status of all eligible infants in a 5-year period admitted within the first 24 h after birth. Read More

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http://dx.doi.org/10.1515/jpm-2018-0295DOI Listing
February 2019

Effect of n-3 long-chain polyunsaturated fatty acids supplementation in healthy mothers on DHA and EPA profiles in maternal and umbilical blood: a randomized controlled trial.

J Perinat Med 2019 Feb;47(2):200-206

Department of Surgery, Mostar Clinical Hospital Center, School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina.

Background The objective of the study was to compare the effect of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) dietary supplementation on their concentration in total lipids (TL) and lipid fractions of maternal and umbilical vein (UV) blood. The specific objective was to analyze the impact of EPA and DHA supplementation on pregnancy outcome and neonatal birth weight. Methods Women were randomly single-blinded (randomized controlled trial; ISRCTN36705743) allocated to the group receiving EPA and DHA supplementation (supplemented group) or the group receiving placebo-corn oil (control group) in the time period from January 1st, 2016 until March 1st, 2017. Read More

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http://www.degruyter.com/view/j/jpme.ahead-of-print/jpm-2018
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http://dx.doi.org/10.1515/jpm-2018-0155DOI Listing
February 2019
3 Reads

Antecedents of red cell transfusion in a large contemporary obstetric cohort.

J Perinat Med 2019 Feb;47(2):195-199

Rotunda Hospital, Parnell Square, Dublin 1, Ireland.

Background Hemorrhage is a critical contributor to maternal morbidity but estimation of blood loss at delivery is frequently inaccurate. Due to this inaccuracy we sought to examine blood transfusion as a surrogate marker for morbidity in a large non-population based consecutive cohort. Methods A retrospective analysis of prospectively gathered data was carried out at two university institutions serving a heterogeneous urban obstetric population from January to December 2016. Read More

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http://www.degruyter.com/view/j/jpme.ahead-of-print/jpm-2018
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http://dx.doi.org/10.1515/jpm-2018-0227DOI Listing
February 2019
10 Reads

Birth risks according to maternal height and weight - an analysis of the German Perinatal Survey.

J Perinat Med 2018 Dec;47(1):50-60

University of Alberta, Department of Medicine, Division of Preventive Medicine, Edmonton, Alberta, Canada.

Objective To investigate the variability in the prevalences of selected birth risks in women of different heights and weights. Methods Data from the German Perinatal Survey of 1998-2000 were analyzed: 503,468 cases contributed to our analysis of the prevalences of selected birth risks specified according to maternal weight groups, 502,562 cases contributed to our analysis according to maternal height groups and 43,928 cases contributed to our analysis of birth risks in women with a body mass index (BMI) of 21-23 kg/m2 but different heights and weights. Data analysis was performed using SPSS version 22. Read More

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http://dx.doi.org/10.1515/jpm-2017-0038DOI Listing
December 2018
6 Reads

What's new in the multiple gestations literature?

J Perinat Med 2018 Oct;46(8):823-824

Jefferson Medical College of Thomas Jefferson University, Department of Obstetrics and Gynecology, 833 Chestnut St., First Floor, Philadelphia, PA 19107, USA, Tel.: +2159557996, Fax: +(215) 955-5041.

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http://dx.doi.org/10.1515/jpm-2018-0304DOI Listing
October 2018
6 Reads

Mechanisms of death in structurally normal stillbirths.

J Perinat Med 2019 Feb;47(2):222-240

Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI, USA.

Objectives To investigate mechanisms of in utero death in normally formed fetuses by measuring amniotic fluid (AF) biomarkers for hypoxia (erythropoietin [EPO]), myocardial damage (cardiac troponin I [cTnI]) and brain injury (glial fibrillary acidic protein [GFAP]), correlated with risk factors for fetal death and placental histopathology. Methods This retrospective, observational cohort study included intrauterine deaths with transabdominal amniocentesis prior to induction of labor. Women with a normal pregnancy and an indicated amniocentesis at term were randomly selected as controls. Read More

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http://dx.doi.org/10.1515/jpm-2018-0216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349478PMC
February 2019
10 Reads
1.430 Impact Factor

Vitamin A and β-carotene in pregnant and breastfeeding post-bariatric women in an urban population.

J Perinat Med 2019 Feb;47(2):183-189

Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Washington-Seattle, Seattle, WA, USA.

Background As breastfeeding awareness and social acceptance are increased, maternal nutritional deficiency requires more investigation. Methods A prospective cohort study was conducted to determine if vitamin A deficiency is more common in pregnant, lactating post-bariatric surgery women in an inner city population. Antepartum, women after bariatric surgery and controls with no history of malabsorption were recruited. Read More

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http://dx.doi.org/10.1515/jpm-2018-0142DOI Listing
February 2019
4 Reads

The diagnostic value of a detailed first trimester anomaly scan in fetuses with increased nuchal translucency thickness.

Authors:
Ismail Tekesin

J Perinat Med 2019 Feb;47(2):241-246

Prenatal Unit Stuttgart, Alte Poststr. 3, D-70173 Stuttgart, Germany, Tel.: +497114006010, Fax: +4971140060120.

Objectives To assess the diagnostic value of an early anomaly scan in fetuses with increased nuchal translucency (NT) in the prediction of aneuploidy. Methods In this study we analyzed the data of pregnant women obtained at their first trimester screening in our unit. The detailed examination routinely includes measurement of NT and a scan for anatomical defects. Read More

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http://dx.doi.org/10.1515/jpm-2018-0145DOI Listing
February 2019
1 Read

Effect of dual tocolysis with fenoterol and atosiban in human myometrium.

J Perinat Med 2019 Feb;47(2):190-194

Division of Obstetrics, Cantonal Hospital, Baden, Switzerland.

Objectives To measure the tocolytic effect of the combination of the oxytocin receptor antagonist atosiban with the β-mimetic agent fenoterol on human myometrium of pregnant women. Methods An in vitro study of contractility in human myometrium at the Laboratory of the Department of Obstetrics, University Hospital of Zürich, Switzerland, was performed. Thirty-six human myometrial biopsies were obtained during elective caesarean sections of singleton pregnancies at term. Read More

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http://dx.doi.org/10.1515/jpm-2018-0010DOI Listing
February 2019
1 Read

Prognostic value of the aortic isthmus Doppler assessment on late onset fetal growth restriction.

J Perinat Med 2019 Feb;47(2):212-217

Fetal Medicine Unit-SAMID, Department of Obstetrics and Gynaecology, University Hospital 12 de Octubre, 12 de Octubre Research Institute (imas12), Complutense University of Madrid, Madrid, Spain.

Background As conflicting results have been reported about the association of reversed flow on the aortic isthmus (AoI) and adverse perinatal results in fetal growth restriction (FGR), we aim to compare perinatal outcomes (including tolerance to labor induction) of late-onset FGR between those with anterograde and reversed AoI flow. Methods This was an observational retrospective cohort study on 148 singleton gestations diagnosed with late-onset FGR (diagnosis ≥32+0 weeks), with an estimated fetal weight (EFW) <10th centile and mild fetal Doppler alteration: umbilical artery (UA) pulsatility index (PI) >95th centile, middle cerebral artery (MCA)-PI <5th centile or cerebral-placental ratio <5th centile. Anterograde AoI flow was present in n=79 and reversed AoI flow in n=69. Read More

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http://www.degruyter.com/view/j/jpme.ahead-of-print/jpm-2018
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http://dx.doi.org/10.1515/jpm-2018-0185DOI Listing
February 2019
22 Reads

Antenatal and prepregnancy care - prevention of perinatal morbidity and mortality.

Authors:
Justin C Konje

J Perinat Med 2018 Sep;46(7):697-700

Executive Chairman Women's Clinical Services Management Group (WCMG), Sidra Medicine, Professor of Obstetrics and Gynaecology, Weill Cornell Medical School, Doha, Qatar.

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http://dx.doi.org/10.1515/jpm-2018-0275DOI Listing
September 2018
1 Read

First trimester prediction of gestational diabetes mellitus using plasma biomarkers: a case-control study.

J Perinat Med 2019 Feb;47(2):161-168

Department of Obstetrics and Gynaecology and Laboratory of Reproductive Biology, Faculty of Medicine, Universidad de Los Andes, San Carlos de Apoquindo 2200, Las Condes, Santiago de Chile, Chile.

Objectives To evaluate the first trimester maternal biomarkers for early pregnancy prediction of gestational diabetes mellitus (GDM). Methods The study was a case-control study of healthy women with singleton pregnancies at the first trimester carried out at the Obstetrics and Gynecology Unit, Clinica Davila, Santiago, Chile. After obtaining informed consent, peripheral blood samples of pregnant women under 14 weeks of gestation were collected. Read More

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http://dx.doi.org/10.1515/jpm-2018-0120DOI Listing
February 2019
2 Reads

Does heart rate variability improve prediction of failed extubation in preterm infants?

J Perinat Med 2019 Feb;47(2):252-257

Transdisciplinary Nucleus for the Study of Chaos and Complexity (NUTECC - FAMERP), São José do Rio Preto, SP, Brazil.

Background Prematurity and its respective comorbidities may result in longer periods of mechanical ventilation in intensive care units (ICU). A method for the assessment of organic maturity would be useful for this population. Heart rate variability (HRV), as an indicator of homeostasis, is a well-established tool for this approach. Read More

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http://www.degruyter.com/view/j/jpme.ahead-of-print/jpm-2017
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http://dx.doi.org/10.1515/jpm-2017-0375DOI Listing
February 2019
3 Reads

Emergency peripartal hysterectomy - a single-center analysis of the last 13 years at a tertiary perinatal care unit.

J Perinat Med 2019 Feb;47(2):169-175

Department of Gynecology and Obstetrics, University Hospital Ulm, Ulm, Germany.

Background Peripartal hysterectomy (PH) is a challenging surgical procedure with elevated maternal morbidity. Methods From 2004 to 2016, 41 emergency PHs were performed at the tertiary care center of the Department of Gynecology and Obstetrics at University Hospital Ulm. In our retrospective analysis, the incidence of PH in our hospital was 12. Read More

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http://dx.doi.org/10.1515/jpm-2018-0149DOI Listing
February 2019

Efficacy and safety of misoprostol vaginal insert vs. oral misoprostol for induction of labor.

J Perinat Med 2019 Feb;47(2):176-182

Department of Obstetrics and Gynecology, University of Basel, University Hospital, Basel, Switzerland.

Objectives To compare the oral application form of misoprostol with the misoprostol vaginal insert (MVI) in a Swiss cohort with special regards to the efficacy and safety. Methods We performed a retrospective case series including a historical group induced with oral misoprostol (MO, n=101) and an MVI group (n=101). The primary outcome was time to delivery. Read More

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http://dx.doi.org/10.1515/jpm-2018-0128DOI Listing
February 2019

Quantitative and qualitative assessment of maternal sexuality during pregnancy.

J Perinat Med 2018 Aug 29. Epub 2018 Aug 29.

University Medical Centre Ljubljana, Division of Obstetrics and Gynaecology, Ljubljana, Slovenia.

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http://dx.doi.org/10.1515/jpm-2018-0206DOI Listing
August 2018
1 Read

Fetal brain development in diabetic pregnancies and normal controls.

J Perinat Med 2018 Sep;46(7):797-803

Department of Obstetrics and Gynecology, University Hospital of Münster, Münster, Germany.

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http://dx.doi.org/10.1515/jpm-2017-0341DOI Listing
September 2018
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Regional differences of hypothermia on oxidative stress following hypoxia-ischemia: a study of DHA and hypothermia on brain lipid peroxidation in newborn piglets.

J Perinat Med 2018 Dec;47(1):82-89

Department of Pediatric Research, Institute of Surgical Research, University of Oslo, Oslo University Hospital Rikshospitalet, Oslo, Norway.

Background Oxidative stress plays an important part in the pathophysiology of hypoxic-ischemic encephalopathy (HIE) and is reliably measured through prostanoids following lipid peroxidation of polyunsaturated fatty acids (PUFAs). The aim of the study is to measure oxidative stress in the prefrontal cortex, white matter and hippocampus in the brains of hypoxic-ischemic piglets treated with docosahexaenoic acid (DHA) and therapeutic hypothermia (TH) and investigate the additive effects of DHA on hypothermia by factorial design. Methods Fifty-five piglets were randomized as having severe global hypoxia (n=48) or not (sham, n=7). Read More

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http://dx.doi.org/10.1515/jpm-2017-0355DOI Listing
December 2018
3 Reads

Prediction of postnatal developmental disabilities using the antenatal fetal neurodevelopmental test: KANET assessment.

J Perinat Med 2018 Dec;47(1):77-81

Department of Pediatrics, Kagawa University Graduate School of Medicine, Miki, Kagawa, Japan.

Objective To assess the usefulness of the antenatal fetal neurodevelopmental test for the prediction of postnatal developmental disabilities. Methods Fetal behavior was assessed with Kurjak's antenatal neurodevelopmental test (KANET) using four-dimensional ultrasound between 28 and 38 weeks of gestation. A score range of 0-5 was characterized as abnormal, from 6 to 9 was considered borderline, and 10-16 was normal. Read More

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http://dx.doi.org/10.1515/jpm-2018-0169DOI Listing
December 2018
9 Reads

Somatic development at birth as influenced by maternal characteristics - an analysis of the German Perinatal Survey.

J Perinat Med 2018 Oct;46(8):889-892

Center for Medicine and Society, University of Freiburg, Freiburg, Germany.

We investigated the effects of maternal age, body weight, body height, weight gain during pregnancy, smoking during pregnancy, previous live births and being a single mother on somatic development at birth. We analysed data from the German Perinatal Survey for the years 1998-2000 from eight German federal states. We had available data on 508,926 singleton pregnancies and neonates in total; for 508,893 of which we could classify the neonates as small, appropriate or large for gestational age (SGA, AGA or LGA) based on the 10th and 90th birth weight percentiles. Read More

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http://dx.doi.org/10.1515/jpm-2017-0039DOI Listing
October 2018

A tribute to Ingrid Gruenberg, Managing Editor of the Journal of Perinatal Medicine and Case Reports in Perinatal Medicine.

J Perinat Med 2018 Aug;46(6):569

Editor-in-Chief, Department of Obstetrics, Charite-Universitatsmedizin Berlin, Augustenburger Platz 1, Berlin 13353, Germany.

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http://dx.doi.org/10.1515/jpm-2018-0235DOI Listing

Serum biomarkers of neuronal injury in newborns evaluated for selective head cooling: a comparative pilot study.

J Perinat Med 2018 Oct;46(8):942-947

Department of Pediatrics, Division of Neonatology, New York University School of Medicine, New York, NY, USA.

Background Evaluation of newborns for hypoxic ischemic encephalopathy (HIE) includes laboratory and clinical parameters, as well as amplitude integrated electroencephalogram (aEEG). Based on qualifying criteria, selective head cooling (SHC) is initiated for infants with evidence of moderate to severe HIE. However, some newborns may not qualify for hypothermia therapy based on normal aEEG. Read More

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http://dx.doi.org/10.1515/jpm-2017-0354DOI Listing
October 2018
5 Reads