27,570,174 results match your criteria Journal of Otolaryngology: Head and Neck Surgery [Journal]

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[Reconstruction of neglected Achilles tendon rupture: flexor hallucis longus transfer versus gastrocnemius turn-down flaps].

Zhonghua Yi Xue Za Zhi 2019 Feb;99(7):542-546

Institute of Sports Medicine, Peking University Third Hospital, Beijing 100191, China.

To compare the outcome of either flexor hallucis longus transfer or turn-down of proximal Achilles tendon tissue repair in treating chronic Achilles tendon rupture. The clinical data of 21 patients who underwent repair of Myerson type Ⅲ chronic Achilles tendon rupture at Peking University Sports Medicine Research Institute from May 2012 to March 2015 were retrospectively analyzed. Among them, 11 cases were treated with flexor hallucis longus (FHL) transfer, and 10 cases were treated with gastrocnemius turn-down flaps repair. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.07.013DOI Listing
February 2019

[Modified Western Ontario and McMaster University Osteoarthritis Index Scale used in patients with knee osteoarthritis].

Zhonghua Yi Xue Za Zhi 2019 Feb;99(7):537-541

Department of Traditional Chinese Medicine, the 2nd Affiliated Hospital of Harbin Medical University, Harbin 150081, China.

To modify Western Ontario and McMaster University Osteoarthritis Index (WOMAC) for more accurate evaluation of patients with knee osteoarthritis in China,and its reliability and validity were measured. The WOMAC was modified through reviewing relevant literatures and practical survey.Total of 120 patients were enrolled in this study. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.07.012DOI Listing
February 2019

[Different care models and symptom progression of Alzheimer's disease in China].

Zhonghua Yi Xue Za Zhi 2019 Feb;99(7):532-536

Department of Psychiatry, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310014, China.

To compare the differences of cognitive function, daily living ability and neuropsychiatric symptoms in patients with sporadic type of Alzheimer's disease (AD) under different care modes, and find the most favorable care mode for delaying the progress of disease. One hundred and twenty cases of AD patients were divided into three groups: Spouse Care Group, Adult Child Care Group and Nursing Home Group. Medical history collection and scale evaluation were carried out by trained specialists on 3 groups of patients and caregivers. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.07.011DOI Listing
February 2019

[Construction and analysis of gene co-expression networks in intracranial aneurysm].

Zhonghua Yi Xue Za Zhi 2019 Feb;99(7):525-531

Department of Neurology, First Affiliated Hospital, Guangxi Medical University, Nanning 530021, China.

To analyze the expression microarray data in the public databases of intracranial aneurysms (IA) using bioinformatics, and to provide important information for the study of disease mechanisms. Gene co-expression network was constructed by weighted gene co-expression network analysis (WGCNA) based on the dataset (GSE75436) and pivot genes were identified. Using the online tool DAVID (Database for Annotation, Visualization, and Integrated Discovery) to perform GO function enrichment and KEGG path analysis on modules highly related to IA. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.07.010DOI Listing
February 2019

[Correlation among serum levels of Irisin, insulin resistance and abdominal obesityin patients with first-episode schizophrenia].

Zhonghua Yi Xue Za Zhi 2019 Feb;99(7):520-524

Department of Psychiatry, First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, China.

To explore the possible role of Irisin in antipsychotic drug-induced insulin resistance and abdominal obesity in patients with schizophrenia and to provide a theoretical basis for the prevention of antipsychotic drug-induced obesity. Fifty-five patients with first-episode schizophrenia, from the First Affiliated Hospital of Zhengzhou University, between January 2016 and December 2017, were admitted as well as fifty healthy controls during the same period. Serum Irisin levels were measured by enzyme-linked immunosorbent assay (ELISA). Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.07.009DOI Listing
February 2019

[Correlation between polymorphism of CYP19A1, GSTM1, GSTT1 and GSTP1 gene and endometriosis].

Zhonghua Yi Xue Za Zhi 2019 Feb;99(7):515-519

Reproductive Medicine Center, the Affiliated Hospital of Inner Mongolia Medical University, Huhehot 010050, China.

To study the association between polymorphisms in CYP19A1 rs2899470, GSTM1, GSTT1, and GSTP1 rs1695 and the development of endometriosis. Between October 2015 and October 2017, 262 endometriosis patients and 275 control subjects were recruited from the Affiliated Hospital of Inner Mongolia Medical University. Genotyping was conducted using polymerase chain reaction-coupled with restriction fragment length polymorphism and multiplex allele specific polymerase chain reaction. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.07.008DOI Listing
February 2019

[Regulatory effect of exosomes secreted by vaginal wall fibroblasts on angiogenesis in patients with stress urinary incontinence].

Zhonghua Yi Xue Za Zhi 2019 Feb;99(7):510-514

Department of Obstetrics & Gynecology, Shanxi Academy of Medical Sciences & Shanxi Da Yi Hospital, Shanxi Da Yi Hospital Affiliated to Shanxi Medical University, Taiyuan 030032, China.

Exosomes are considered to mediate intercellular communication by delivering biomolecules like mRNA, miRNA into recipient cells. The purpose of this study was to evaluate the effects of exosomes secreted by fibroblasts from women with stress urinary incontinence (SUI-EXO) on endothelial cells angiogenesis. Primary fibroblasts were acquired from periurethral vaginal wall tissues and exosomes were prepared by ultracentrifugation of fibroblasts cells conditioned medium. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.07.007DOI Listing
February 2019

[The effect of Cathepsin S in primary biliary cholangitis].

Zhonghua Yi Xue Za Zhi 2019 Feb;99(7):505-509

Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Key Laboratory of Rheumatology and Cinical Immunology, Ministry of Education, Beijing 100730, China.

To explore the effect of cathepsin (Cat) S in primary biliary cholangitis (PBC). The serum of PBC patients and Hepatitis B virus (HBV) patients were collected in Peking Union Medical College Hospital from August 2016 to July 2017 and the liver tissue of PBC were collected from March 2010 to July 2013. Indirect enzyme-linked immunosorbent assay (ELISA) was used to detect the serum concentrations of total-and pro-Cat S respectively in 24 PBC patients, 24 Hepatitis B patients and 24 healthy controls. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.07.006DOI Listing
February 2019
5 Reads

[Application of stretched exponential diffusion-weighted imaging model in quantitative diagnosis of nonalcoholic fatty liver disease: in a rabbit model].

Zhonghua Yi Xue Za Zhi 2019 Feb;99(7):500-504

Department of Radiology, Northern Jiangsu People's Hospital, Clinical Medical School of Yangzhou University, Yangzhou 225001, China.

To evaluate the feasibility of diffusion parameters obtained from mono-exponential and stretched exponential diffusion-weighted imaging models in staging of nonalcoholic fatty liver disease and compare the diagnosis ability of nonalcoholic steatohepatitis. Thirty-two 12 -week-old male New Zealand rabbits, about 2.5 kg of each, were randomly divided into five groups. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.07.005DOI Listing
February 2019

[Magnetic resonance imaging and diffusion weighted imaging features of focal peliosis hepatis].

Zhonghua Yi Xue Za Zhi 2019 Feb;99(7):496-499

Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Medical Imaging, Department of Medical Imaging, Shanghai Medical College, Fudan University, Shanghai 200032, China.

To investigate the MRI and diffusion weighted imaging (DWI) features of focal peliosis hepatis. The clinical data and MRI of 19 cases with focal peliosis hepatis confirmed by pathology from January 2012 to March 2018 in Zhongshan Hospital of Fudan University were retrospectively analyzed. The number, location, size, shape, signal intensity of plain scan of lesions, enhancement pattern of lesions, vessels within lesions, and perfusion disorders of hepatic parenchyma were analyzed. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.07.004DOI Listing
February 2019

[Computer-aided assessment of liver fibrosis progression in patients with chronic hepatitis B: an exploratory research].

Zhonghua Yi Xue Za Zhi 2019 Feb;99(7):491-495

Department of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai Institute of Medical Imaging, Fudan University, Shanghai 200032, China.

To establish automatic liver fibrosis classification models by using traditional machine learning and deep learning methods and preliminaryly evaluate the efficiency. Gray scale ultrasound images and corresponding elastic images of 354 patients, 247 males and 107 females, mean age (54±12) years undergoing partial hepatectomy in Zhongshan Hospital of Fudan University from November 2014 to January 2016 were enrolled in this study. By using traditional machine learning and deep learning methods, an automatic classification model of liver fibrosis stages (S0 to S4) were established through feature extraction and classification of ultrasound image data sets and the accuracy in different classification categories of each model were calculated, by using liver biopsy as the reference standard. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.07.003DOI Listing
February 2019

[The imaging study and progress of liver fibrosis should be emphasized].

Zhonghua Yi Xue Za Zhi 2019 Feb;99(7):481-483

Department of Medical Imaging, Tongji Hospital of Tongji University, Shanghai 200065, China.

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.07.001DOI Listing
February 2019

[Trans-jugular transcatheter closure of atrial septal defect solely under echocardiography guidance in infants].

Zhonghua Yi Xue Za Zhi 2019 Feb;99(6):458-461

Department of Cardiovascular Surgery, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100037, China.

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.06.015DOI Listing
February 2019

[Effects of penehyclidine hydrochloride on Nrf2/ARE signaling pathway during endotoxin-induced acute lung injury in neonate rats].

Zhonghua Yi Xue Za Zhi 2019 Feb;99(6):453-457

Department of Anesthesiology, Affiliated Anti-cancer Hospital of Zhengzhou University, Zhengzhou 450008, China.

To evaluate the effects of penehyclidine hydrochloride on the nuclear factor erythroid 2-related factor 2/antioxidant responsive element (Nrf2/ARE) signaling pathway during endotoxin-induced acute lung injury(ALI) in neonate rats. Forty 7-day-old Wistar rats weighing 12-18 g were randomly divided into 4 groups (10) using a random number table: normal saline group(NS group), acute lung injury(ALI group), penehyclidine hydrochloride group(PHC group) and penehyclidine hydrochloride+ Nrf2 siRNA plasmid group(PNS group). The ALI model was induced with intraperitoneal endotoxin (5. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.06.014DOI Listing
February 2019
1 Read

[Establishment of rat model of cardiorenal syndrome by transabdominal subtotal nephrectomy].

Zhonghua Yi Xue Za Zhi 2019 Feb;99(6):447-452

Department of Cardiovascular Surgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China.

To evaluate the changes of rat renal function and cardiac function after transabdominal subtotal nephrectomy (STNx) and provide an ideal animal model for the study of chronic kidney disease (CKD) and cardiorenal syndrome (CRS). The SD rats (male, 5-6 weeks) were randomly divided into Sham group (10) and STNx group (10). The rats from Sham group underwent sham surgery, and the right nephrectomy plus the 2/3 left kidney artery ligation through abdominal incision were performed in the rats from STNx group. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.06.013DOI Listing
February 2019

[Changes of intestinal mucosal barrier function and effects of early enteral nutrition in patients with severe organophosphorus poisoning].

Zhonghua Yi Xue Za Zhi 2019 Feb;99(6):442-446

Intensive Care Unit, Bozhou People's Hospital Affiliated to Anhui University of Science and Technology, Bozhou 236800, China.

To observe the changes of intestinal barrier function in patients with acute severe organophosphorus pesticide poisoning (ASOPP) and the effect of early enteral nutrition on them. A single-center, single-sample, prospective, randomized controlled clinical trial was conducted. A total of 50 patients with ASOPP were divided into 24 h enteral nutrition group (group A) and 48 h (48-72 h) enteral nutrition group (B group) according to the order of hospitalization. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.06.012DOI Listing
February 2019

[Analysis of adverse events of clinical blood use except for the adverse reactions of blood transfusion].

Zhonghua Yi Xue Za Zhi 2019 Feb;99(6):438-441

Department of Blood Transfusion, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.

To reduce the occurrence of adverse events of clinical blood use by analyzing the clinical adverse events of blood use except for the adverse reactions of blood transfusion. A retrospective analysis was performed on 294 cases of adverse events of clinical blood use other than adverse blood transfusion reactions in Shijitan hospital from January 2014 to December 2017, and a statistical analysis was made on the types of adverse events of clinical blood use, blood transfusion related departments, and internal and surgical blood use. The incidence of adverse events of clinical blood use was 10. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.06.011DOI Listing
February 2019

[Diagnostic value of multiplex ligation dependent probe amplification combined with Sanger sequencing in 21-hydroxylase deficiency].

Zhonghua Yi Xue Za Zhi 2019 Feb;99(6):432-437

Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Key Laboratory of Endocrinology, National Health Commission, Beijing 100730, China.

To study the procedure of gene mutation detection in 21-hydroxylase deficiency (21-OHD) patients. The detail clinical and biochemical data of 51 patients with 21-OHD [18 males and 33 females, with an average age of (16.4±9. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.06.010DOI Listing
February 2019

[Complications of transperineal template-guided prostate mapping biopsy].

Zhonghua Yi Xue Za Zhi 2019 Feb;99(6):428-431

Department of Urology, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou 225001, China.

To assess the complications of transperineal template-guided prostate mapping biopsy (TTMB). Between May 2017 and March 2018, 142 consecutive patients with prior negative transrectal biopsy results and persistently elevated prostate-specific antigen (PSA) were divided into the observation group and the control group randomly. The observation group underwent TTMB and the control group underwent transperineal template-guided prostate saturation biopsy (TTSB). Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.06.009DOI Listing
February 2019

[Comparative observation of thulium laser resection of the prostate-tangerine technique and transurethral resection of the prostate for the treatment of benign prostatic hyperplasia of various sizes].

Zhonghua Yi Xue Za Zhi 2019 Feb;99(6):423-427

Department of Urology, Guizhou Provincial People's Hospital, Guiyang 550002, China.

To compare the efficiency and safety of thulium laser resection of the prostate-tangerine technique (TmLRP-TT) and transurethral resection of the prostate (TURP) for the treatment of benign prostatic hyperplasia (BPH) of various sizes. Clinical data of 249 BPH patients received TmLRP-TT or TURP were retrospectively collected. Patients were divided into small prostate group [prostate volume (PV)<40 ml], medium prostate group (40 ml≤PV<80 ml) and large prostate group (PV ≥ 80 ml) based on transrectal ultrasound (TRUS) results. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.06.008DOI Listing
February 2019

[Activation of GPER inhibts proliferation and autophagy in prostatic epithelial cells].

Zhonghua Yi Xue Za Zhi 2019 Feb;99(6):419-422

Department of Urology, the First Affiliated Hospital of Guangzhou Medical College, Guangdong Key Laboratory of Urology, Guangzhou 510230, China.

To investigate the effect of G protein-coupled estrogen receptor (GPER) on proliferation and autophagy in prostatic epithelial cells. Cell Counting Kit-8 (CCK8) assay was used to observe the growth of BPH-1 and RWPE-1 cells after treating with or not with estradiol or GPER selective agonist G1. Autophagy was quantified with Western blot and Cyto-ID autophagy detection kit after treating with estradiol, G1 or both G1 and G15 in the same cells. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.06.007DOI Listing
February 2019

[Current view on obstructive sleep apnea in idiopathic pulmonary fibrosis].

Authors:
Q Y Li A L Song

Zhonghua Yi Xue Za Zhi 2019 Feb;99(6):416-418

Wuxi Branch of Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Wuxi 214000, China.

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.06.006DOI Listing
February 2019
1 Read

[Bronchial asthma and obstructive sleep apnea].

Zhonghua Yi Xue Za Zhi 2019 Feb;99(6):414-415

The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Health, National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou 510120, China.

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.06.005DOI Listing
February 2019
2 Reads

[Sleep and sleep related breathing disorders in chronic obstructive pulmonary disease].

Authors:
W Wang

Zhonghua Yi Xue Za Zhi 2019 Feb;99(6):411-413

Department of Respiratory and Critical Care Medicine, the First Hospital of China Medical University, Shenyang 110001, China.

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.06.004DOI Listing
February 2019

[Sleep and sleep breathing problems in lung cancer patients].

Authors:
X L Zhang B Y Chen

Zhonghua Yi Xue Za Zhi 2019 Feb;99(6):407-410

Department of Respiratory and Critical Care Medicine, Tianjin Medical University General Hospital, Tianjin 300052, China.

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.06.003DOI Listing
February 2019

[Focus on complications of flexible ureteroscopic lithotripsy].

Zhonghua Yi Xue Za Zhi 2019 Feb;99(6):404-406

Department of Urology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200080, China.

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.06.002DOI Listing
February 2019

[Recognize sleep disorder in patients with common respiratory diseases].

Authors:
F Han B Y Chen

Zhonghua Yi Xue Za Zhi 2019 Feb;99(6):401-403

Department of Respiratory and Critical Care Medicine, Tianjin Medical University General Hospital, Tianjin 300052, China.

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.06.001DOI Listing
February 2019

An International Summit in Human Genetics and Genomics: Empowering clinical practice and research in developing countries.

Mol Genet Genomic Med 2019 Jan;7(1):e00599

National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland.

To help fill the knowledge gap in human genetics and genomics, an International Summit (IS) in Human Genetics and Genomics was conceived and organized by the National Human Genome Research Institute (NHGRI) of the National Institutes of Health (NIH) as a 5-year initiative, from 2016 to 2020. In its first 3 years, 71 professionals from 34 countries received training. Read More

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http://dx.doi.org/10.1002/mgg3.599DOI Listing
January 2019

The self-perceptions of aging were an important factor associated with the quality of life in Chinese elderly with hypertension.

Psychogeriatrics 2019 Feb 20. Epub 2019 Feb 20.

Division of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, China.

Background: In China, quality of life (QOL) of the elderly with hypertension was lower than that of normal elderly and lower self-perceptions of aging (SPA) in the elderly with chronic diseases have been shown. Previous studies showed that SPA played a key role in QOL of the elderly. We hypothesised that SPA were associated with QOL in Chinese elderly with hypertension, with more negative SPA predicting lower QOL. Read More

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http://dx.doi.org/10.1111/psyg.12400DOI Listing
February 2019

Quantitative CT-derived vessel metrics in idiopathic pulmonary fibrosis: A structure-function study.

Respirology 2019 Feb 20. Epub 2019 Feb 20.

Ludwig Boltzmann Institute for Lung Vascular Research, Graz, Austria.

Background And Objective: This study aimed to investigate whether quantitative lung vessel morphology determined by a new fully automated algorithm is associated with functional indices in idiopathic pulmonary fibrosis (IPF).

Methods: A total of 152 IPF patients had vessel volume, density, tortuosity and heterogeneity quantified from computed tomography (CT) images by a fully automated algorithm. Separate quantitation of vessel metrics in pulmonary arteries and veins was performed in 106 patients. Read More

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http://dx.doi.org/10.1111/resp.13485DOI Listing
February 2019
1 Read

Intensity-modulated radiation therapy dose prescription and reporting: Sum and substance of the International Commission on Radiation Units and Measurements Report 83 for veterinary medicine.

Vet Radiol Ultrasound 2019 Feb 20. Epub 2019 Feb 20.

Division of Radiation Oncology, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.

Institutions' adherence to protocol, quality assurance, and radiation parameter reporting are key to adequately interpret and compare treatment outcomes in radiation oncology. In 2017, the editorial board for Veterinary Radiology & Ultrasound adapted author guidelines on "technical information for radiation therapy (RT)". These guidelines provide a framework to report the RT treatment process in manuscripts resulting from veterinary clinical trials. Read More

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http://dx.doi.org/10.1111/vru.12722DOI Listing
February 2019

Abdominal CT evaluation of the liver and spleen for staging mast cell tumors in dogs yields nonspecific results.

Vet Radiol Ultrasound 2019 Feb 20. Epub 2019 Feb 20.

Department of Clinical Sciences and Services, The Royal Veterinary College, North Mymms, Hatfield, AL9 7TA, UK.

Canine mast cell tumor staging is commonly performed using abdominal ultrasonography and fine-needle aspiration cytology of masses, lymph nodes, and hepatic and splenic parenchyma. Computed tomography is used for abdominal, thoracic, or whole body imaging in staging mast cell tumors in the authors' institution enabling evaluation of multiple body areas in one examination. The aim of this study was to compare the CT examinations acquired for staging of mast cell disease to their subsequent liver and spleen cytology findings. Read More

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http://dx.doi.org/10.1111/vru.12717DOI Listing
February 2019

The prevalence and diagnostic classification of mixed features in patients with major depressive episodes: A multicenter study based on the DSM-5.

Int J Methods Psychiatr Res 2019 Feb 20:e1773. Epub 2019 Feb 20.

Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Objectives: The purpose of this study was to evaluate the prevalence of mixed features using the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) and to examine how patients with mixed states would be classified using the DSM-5.

Methods: In total, 12 hospitals participated in this study, and data on the demographic characteristics and clinical diagnoses of patients treated between October 2013 and September 2016 were obtained. We reviewed the data for opposite-polarity symptoms according to the DSM-5 criteria and the research-based diagnostic criteria. Read More

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http://doi.wiley.com/10.1002/mpr.1773
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http://dx.doi.org/10.1002/mpr.1773DOI Listing
February 2019
4 Reads

Legal and ethical implications of defining an optimum means of achieving unconsciousness in assisted dying.

Anaesthesia 2019 Feb 20. Epub 2019 Feb 20.

Nuffield Department of Anaesthetics, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

A decision by a society to sanction assisted dying in any form should logically go hand-in-hand with defining the acceptable method(s). Assisted dying is legal in several countries and we have reviewed the methods commonly used, contrasting these with an analysis of capital punishment in the USA. We expected that, since a common humane aim is to achieve unconsciousness at the point of death, which then occurs rapidly without pain or distress, there might be a single technique being used. Read More

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http://dx.doi.org/10.1111/anae.14532DOI Listing
February 2019

Clonal expansion of hepatic progenitor cells and differentiation into hepatocyte-like cells.

Dev Growth Differ 2019 Feb 20. Epub 2019 Feb 20.

Department of Hepatobiliary Surgery, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Hepatic progenitor cells (HPCs) in adult liver are promising for treatment of liver diseases. A biliary-derived HPC population in adult mice has been characterized by co-expression of stem cell marker Sry (sex determining region Y)-box 9 (SOX9) and biliary marker cytokeratin 7 (CK7). However, isolation of these HPCs in adult healthy liver without any selection procedures remains a big challenge in this field. Read More

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http://dx.doi.org/10.1111/dgd.12596DOI Listing
February 2019

[Alternative Psychoses and Forced Normalization after Seizure Control by Anticonvulsants with Special Consideration of the New Anticonvulsants].

Fortschr Neurol Psychiatr 2019 Feb 20. Epub 2019 Feb 20.

Zentrum für Psychiatrie Südwürttemberg, Klinik für Psychiatrie und Psychotherapie I, Universität Ulm.

In the case of alternative psychosis and forced normalization, the patient alternates between periods of clinically manifest seizures and normal behavior, and other periods of seizure freedom (or significant seizure reduction) accompanied by psychosis or behavioral disturbances. Unlike the clinically defined alternative psychosis, forced normalization is based on EEG findings. In clinical practice and in the literature, both terms are mostly used synonymously, and they also describe the same clinical pictures. Read More

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http://dx.doi.org/10.1055/a-0820-3345DOI Listing
February 2019

[Advance research directives in the context of dementia research: Ethical reflections on the disclosure requirement].

Fortschr Neurol Psychiatr 2019 Feb 20. Epub 2019 Feb 20.

Ruhr-Universität Bochum, Medizinische Fakultät, Institut für medizinische Ethik und Geschichte der Medizin.

In November 2016, the German Federal Diet adopted an amendment to the German Medicinal Products Act (Arzneimittelgesetz), which permits non-therapeutic biomedical research on incompetent adults under a number of strict conditions. One of these conditions is that the potential research participant has declared her wish to participate in biomedical research in a valid research advance directive. Before completing the research advance directive, the potential research participant must be informed about the circumstances of research participation. Read More

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http://dx.doi.org/10.1055/a-0664-7980DOI Listing
February 2019

Sphincterotomy plus balloon dilation versus sphincterotomy alone for choledocholithiasis: a meta-analysis.

Endoscopy 2019 Feb 20. Epub 2019 Feb 20.

Department of Gastroenterology, Zhongnan Hospital of Wuhan University, Wuhan, China.

Background:  Endoscopic sphincterotomy plus balloon dilation (ESBD) is considered to be a promising method for the removal of large common bile duct (CBD) stones. However, when compared with endoscopic sphincterotomy (EST) alone, the efficacy and safety of ESBD remain controversial. This meta-analysis aimed to compare the efficacy and safety of ESBD vs. Read More

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http://dx.doi.org/10.1055/a-0848-8271DOI Listing
February 2019

Acoustic Radiation Force Impulse Elastography and Ultrasonographic Findings of Achilles Tendon in Patients With and Without Diabetic Peripheral Neuropathy: A Cross-Sectional Study.

Exp Clin Endocrinol Diabetes 2019 Feb 20. Epub 2019 Feb 20.

Department of Endocrinology and Metabolism, Başkent University, Ankara, Turkey.

Aims: We aimed to evaluate the elastographic features of Achilles tendon with Acoustic Radiation Force Impulse in patients with and without diabetic neuropathy.

Methods: According to the presence of peripheral neuropathy, 45 patients with type 2 diabetes were divided into 2 subgroups. Those with peripheral neuropathy were defined as group I (22 patients) and those without peripheral neuropathy were defined as group II (23 patients). Read More

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http://dx.doi.org/10.1055/a-0840-3292DOI Listing
February 2019

[Incidental finding: TCC or "the lucky colic"].

Authors:
Pierre Einwaller

Aktuelle Urol 2019 Feb 20. Epub 2019 Feb 20.

Alexianer Krefeld GmbH, Klinik für Urologie und Kinderurologie, Krefeld.

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http://dx.doi.org/10.1055/a-0848-8004DOI Listing
February 2019

Comments on: Isolated Nonocompaction Suggests Subclinical Myopathy.

Authors:
Josef Finsterer

Rev Bras Ginecol Obstet 2019 Feb 20;41(2):135-136. Epub 2019 Feb 20.

Krankenanstalt Rudolfstiftung, Messerli Institute, Veterinary University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1055/s-0038-1676600DOI Listing
February 2019

Comments on: Limitations of HPV DNA Testing in Screening of Cervical Adenocarcinomas.

Rev Bras Ginecol Obstet 2019 Feb 20;41(2):133-134. Epub 2019 Feb 20.

Lâmina Laboratory of Pathology and Cancer Prevention, Brasília, DF, Brazil.

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http://dx.doi.org/10.1055/s-0039-1678591DOI Listing
February 2019

Lithopedion Causing Intestinal Obstruction in a 71-Year-Old Woman: A Case Report Litopedia causando obstrução intestinal em idosa de 71 anos: relato de caso.

Rev Bras Ginecol Obstet 2019 Feb 20;41(2):129-132. Epub 2019 Feb 20.

Division of Medicine, Fortaleza Health Squadron, Força Aérea Brasileira, Fortaleza, CE, Brazil.

Ectopic pregnancy is the leading cause of pregnancy-related death during the first trimester, and it occurs in 1 to 2% of pregnancies. Over 90% of ectopic pregnancies are located in the fallopian tube. Abdominal pregnancy refers to an ectopic pregnancy that has implanted in the peritoneal cavity, external to the uterine cavity and fallopian tubes. Read More

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http://dx.doi.org/10.1055/s-0038-1676060DOI Listing
February 2019

Occult Urinary Incontinence Treatment: Systematic Review and Meta-analysis-Brazilian Guidelines.

Rev Bras Ginecol Obstet 2019 Feb 20;41(2):116-123. Epub 2019 Feb 20.

Faculty of Medicine, Universidade de São Paulo, São Paulo, SP, Brazil.

Objective:  To evaluate if performing anti-incontinence procedures during surgical anterior and/or apical prolapse correction in women with asymptomatic urinary incontinence (UI) may prevent stress urinary incontinence (SUI) postoperatively.

Methods:  We have performed a systematic review of articles published in the PubMed, Cochrane Library, and Lilacs databases until March 31, 2016. Two reviewers performed the data collection and analysis, independently. Read More

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http://dx.doi.org/10.1055/s-0038-1676842DOI Listing
February 2019

Effectiveness of Insulin Analogs Compared with Human Insulins in Pregnant Women with Diabetes Mellitus: Systematic Review and Meta-analysis.

Rev Bras Ginecol Obstet 2019 Feb 20;41(2):104-115. Epub 2019 Feb 20.

Universidade Federal de Alagoas, Maceió, AL, Brazil.

Diabetes during pregnancy has been linked to unfavorable maternal-fetal outcomes. Human insulins are the first drug of choice because of the proven safety in their use. However, there are still questions about the use of insulin analogs during pregnancy. Read More

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http://dx.doi.org/10.1055/s-0038-1676510DOI Listing
February 2019

International Federation of Gynecology and Obstetrics Global Declaration on Cervical Cancer Elimination.

Authors:

Rev Bras Ginecol Obstet 2019 Feb 20;41(2):102-103. Epub 2019 Feb 20.

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http://dx.doi.org/10.1055/s-0039-1679865DOI Listing
February 2019

The Use of Mobile Educational Tools to Improve Antimicrobial Prescription for the Treatment of Acute Pyelonephritis in Pregnancy: A Retrospective Cross-sectional Study.

Rev Bras Ginecol Obstet 2019 Feb 20;41(2):97-101. Epub 2019 Feb 20.

Graduate Program in Medicine and Health Sciences, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, RS, Brazil.

Objective:  To analyze the prescription of antimicrobial agents for pregnant women admitted into the obstetrics service who presented with acute pyelonephritis.

Methods:  Three cross-sectional studies were performed comparing the prescription of antimicrobials for pyelonephritis in pregnant women in the time periods evaluated (2010-2011: 99 patients evaluated; 2013: 116 patients evaluated; 2015: 107 patients evaluated), at the Hospital Fêmina, Porto Alegre, in the state of Rio Grande do Sul, Brazil. The analysis was performed before and after the promotion of an institutional protocol for the treatment of pyelonephritis during pregnancy, and on a third occasion after the introduction of a smartphone-based mobile educational tool. Read More

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http://dx.doi.org/10.1055/s-0039-1678590DOI Listing
February 2019
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Syphilis in Pregnancy: The Reality in a Public Hospital.

Rev Bras Ginecol Obstet 2019 Feb 20;41(2):90-96. Epub 2019 Feb 20.

Department of Fetal Medicine, Universidade Federal do Triângulo Mineiro, Uberaba, MG, Brazil.

Objective:  The present study assessed epidemiological and obstetrical data from pregnant women with syphilis at the Hospital de Clínicas of the Universidade Federal do Triângulo Mineiro (UFTM, in the Portuguese acronym), describing this disease during pregnancy and its vertical transmission for future healthcare actions.

Methods:  Records from pregnant women who had been admitted to the Obstetrics Department of the Hospital de Clínicas of the UFTM and were diagnosed with syphilis between 2007 and 2016 were reviewed. A standardized form was used to collect epidemiological, obstetric data and outcomes of congenital infection. Read More

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http://dx.doi.org/10.1055/s-0038-1676569DOI Listing
February 2019

Pethidine in Low Doses versus Dipyrone for Pain Relief in Labor: A Randomized Controlled Trial.

Rev Bras Ginecol Obstet 2019 Feb 20;41(2):84-89. Epub 2019 Feb 20.

Graduate Program in Medical Sciences, Universidade de Fortaleza, Fortaleza, CE, Brazil.

Objective:  To compare low doses of pethidine with dipyrone in labor analgesia.

Methods:  In a randomized prospective study conducted by Universidade de Fortaleza, in the state of Ceará, Brazil, between May and December 2016, 200 full-term parturients, with very painful uterine contractions and exhibiting uterine cervix dilatation ≥ 5 cm, were selected to receive a single intravenous dose of either 0.25 mg/kg of pethidine ( = 100) or of 25 mg/kg of dipyrone ( = 100). Read More

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http://dx.doi.org/10.1055/s-0038-1676509DOI Listing
February 2019

Answering the Call to Accelerate the Elimination of Cervical Cancer.

Authors:
Joanna M Cain

Rev Bras Ginecol Obstet 2019 Feb 20;41(2):67. Epub 2019 Feb 20.

School of Medicine, Department of Obstetrics and Gynecology, University of Massachusetts, Massachusetts, United States.

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http://dx.doi.org/10.1055/s-0039-1679864DOI Listing
February 2019
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