1,667 results match your criteria Journal of Ophthalmology [Journal]


Characteristics and Risk Factors for Spontaneous Closure of Idiopathic Full-Thickness Macular Hole.

Authors:
Xida Liang Wu Liu

J Ophthalmol 2019 13;2019:4793764. Epub 2019 Mar 13.

Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Ophthalmology and Visual Sciences Key Laboratory, Capital Medical University, Beijing 100730, China.

Idiopathic full-thickness macular hole is a severe visual impairment disease. Pars plana vitrectomy remains the primary treatment option for idiopathic full-thickness macular holes, and over 90% idiopathic full-thickness macular holes are closed by vitrectomy surgery. However, the full-thickness macular hole may close spontaneously, with a good visual acuity progress. Read More

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http://dx.doi.org/10.1155/2019/4793764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436358PMC

Sulfur Hexafluoride (SF) versus Perfluoropropane (CF) in the Intraoperative Management of Macular Holes: A Systematic Review and Meta-Analysis.

J Ophthalmol 2019 12;2019:1820850. Epub 2019 Mar 12.

Department of Ophthalmology, Rambam Health Care Campus, Haifa, Israel.

Purpose: A systematic literature search was conducted to identify and review studies comparing SF to CF as a tamponade agent in the intraoperative management of macular holes.

Methods: Publications up to October 2018 that focused on macular hole surgery in terms of primary closure, complications, and clinical outcomes were included. Forest plots were created using a weighted summary of proportion meta-analysis. Read More

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http://dx.doi.org/10.1155/2019/1820850DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434271PMC

10-Year Results of Standard Cross-Linking in Patients with Progressive Keratoconus in Romania.

J Ophthalmol 2019 7;2019:8285649. Epub 2019 Mar 7.

Oculens Clinic, Cluj-Napoca, Romania.

Purpose: The purpose of the current study was to evaluate the long-term functional results based on keratometric measurements, spherical and cylinder equivalent in patients with progressive keratoconus treated with conventional "epi-off" corneal collagen cross-linking (CXL).

Methods: We conducted a retrospective study in which 113 eyes from 90 keratoconus-treated patients with CXL between 2006 and 2008 in Oculens Eye Clinic from Cluj-Napoca, Romania, were included. The diagnosis of keratoconus was based on corneal topography and its clinical signs. Read More

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https://www.hindawi.com/journals/joph/2019/8285649/
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http://dx.doi.org/10.1155/2019/8285649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431502PMC
March 2019
1 Read

Macular Hole in Myopic Eyes: A Narrative Review of the Current Surgical Techniques.

J Ophthalmol 2019 11;2019:3230695. Epub 2019 Mar 11.

Eye Clinic, Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.

Macular hole (MH) in myopic eyes is a disease arising from complex tractional forces exerted by vitreomacular interface, epiretinal tissue, and progressive scleral ectasia of the posterior ocular globe wall. This retinal disease requires vitreoretinal treatment for its repair, and the surgical intervention remains a challenge also for experienced surgeons. The aim of this review is to describe the current knowledge regarding the pathogenesis of MH in myopic eyes and to detail novel surgical techniques and technological advancements in its surgical management. Read More

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https://www.hindawi.com/journals/joph/2019/3230695/
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http://dx.doi.org/10.1155/2019/3230695DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432738PMC
March 2019
1 Read

Current State and Future Trends: A Citation Network Analysis of the Orthokeratology Field.

J Ophthalmol 2019 7;2019:6964043. Epub 2019 Mar 7.

Faculty of Biomedical and Health Sciences, Universidad Europea de Madrid, Madrid 20822, Spain.

Introduction: Citation network analysis is a powerful tool that allows for a visual and objective representation of the past, present, and potential future directions of a research field. The objective of this study is using citation analysis network to analyse the evolution of knowledge in the field of orthokeratology.

Materials And Methods: The database used in this citation networks analysis study was Scopus. Read More

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http://dx.doi.org/10.1155/2019/6964043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431452PMC
March 2019
1 Read

An Internal Limiting Membrane Plug and Gas Endotamponade for Recurrent or Persistent Macular Hole.

J Ophthalmol 2019 7;2019:6051724. Epub 2019 Mar 7.

Dipartimento Neuro-muscoloscheletrico e Organi di Senso, Azienda Ospedaliera Universitaria di Careggi, Florence, Italy.

Introduction: Recurrent or persistent macular holes (MHs) are rare today due to the tendency to carefully peel the internal limiting membrane. Conversely, their treatment is still a challenge for a vitreoretinal surgeon.

Materials And Methods: This is a retrospective, consecutive, and nonrandomized study of patients affected by recurrent or persistent MHs treated using small-gauge pars plana vitrectomy (25- or 23-gauge) and an autologous ILM plug, at the Eye Clinic of Azienda Ospedaliera Universitaria Careggi (Florence, Italy) between January 2016 and May 2018. Read More

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http://dx.doi.org/10.1155/2019/6051724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431435PMC
March 2019
1 Read

Comparison of Toric and Spherical Orthokeratology Lenses in Patients with Astigmatism.

J Ophthalmol 2019 20;2019:4275269. Epub 2019 Feb 20.

Department of Ophthalmology, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.

Purpose: This retrospective study aimed at comparing the efficacy and safety of toric and spherical orthokeratology lenses in the treatment of patients with moderate to high astigmatism.

Methods: Fifty adolescents with myopia and moderate to high astigmatism (≥1.50 D) who underwent consecutive orthokeratology treatment for at least 1 year were included in this study. Read More

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http://dx.doi.org/10.1155/2019/4275269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425404PMC
February 2019

Corrigendum to "The Role of Medications in Causing Dry Eye".

J Ophthalmol 2019 4;2019:2989680. Epub 2019 Mar 4.

Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, 3375 SW Terwilliger BouLevard, Portland, OR 97239-4197, USA.

[This corrects the article DOI: 10.1155/2012/285851.]. Read More

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http://dx.doi.org/10.1155/2019/2989680DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425369PMC

Visual Performance after a Unilateral or Bilateral Implantation of Enlarged Depth-of-Focus Intraocular Lens in Patients with Cataract: A Prospective Clinical Trial.

J Ophthalmol 2019 4;2019:2163809. Epub 2019 Mar 4.

Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea.

Purpose: To investigate visual performances after a unilateral or bilateral implantation of enlarged depth-of-focus intraocular lens in patients with cataract.

Methods: In this prospective study, uneventful phacoemulsification and TECNIS® Symfony intraocular lens implantation were performed in 20 eyes of 17 patients. At postoperative 1, 4, and 12 weeks, the logarithm of the minimal angle of resolution visual acuity at far, intermediate, and near distances and the spherical equivalent in manifest refraction and automated refraction were measured. Read More

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https://www.hindawi.com/journals/joph/2019/2163809/
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http://dx.doi.org/10.1155/2019/2163809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425413PMC
March 2019
5 Reads
1.935 Impact Factor

Modeling a Telemedicine Screening Program for Diabetic Retinopathy in Iran and Implementing a Pilot Project in Tehran Suburb.

J Ophthalmol 2019 4;2019:2073679. Epub 2019 Mar 4.

Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Purpose: To model a community-based telescreening program for diabetic retinopathy (DR) in Iran and to implement a pilot project at the Iranian Diabetes Society (IDS) branch in a Tehran suburb.

Methods: In this mixed model study, a web application called the "Iranian Retinopathy Teleophthalmology Screening (IRTOS)" was launched. The educational course for DR screening was established for general practitioners (GPs). Read More

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http://dx.doi.org/10.1155/2019/2073679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425400PMC
March 2019
1 Read

Morphology of Inner Retina in Rhesus Monkeys of Various Ages: A Comparative Study.

J Ophthalmol 2019 3;2019:7089342. Epub 2019 Mar 3.

Laboratory of Animal Disease Model, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, Sichuan, China.

Purpose: To investigate the changes of thickness in each layer, the morphology and density of inner neurons in rhesus monkeys' retina at various growth stages, thus contribute useful data for further biological studies.

Methods: The thickness of nerve fiber layer (NFL), the whole retina, inner plexiform layer (IPL), and outer plexiform layer (OPL) of rhesus monkeys at different ages were observed with hematoxylin and eosin (H&E) staining. The morphology and the density of inner neurons of rhesus monkey retina were detected by immunofluorescence. Read More

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http://dx.doi.org/10.1155/2019/7089342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421773PMC

Reconstruction of Upper Eyelid Defects Secondary to Malignant Tumors with a Newly Modified Cutler-Beard Technique with Tarsoconjunctival Graft.

J Ophthalmol 2019 3;2019:6838415. Epub 2019 Mar 3.

Ophthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, Spain.

Purpose: We describe a modification of Cutler-Beard's technique, using a contralateral tarsoconjunctival graft, in patients who underwent excision of large malignant tumors of the upper eyelid.

Methods: This is an interventional retrospective review (clinical study) of ten cases, with age range from 64 to 86 years (mean: 71.2 years ± 6. Read More

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http://dx.doi.org/10.1155/2019/6838415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421748PMC
March 2019
1 Read

Anterior Segment Biometry with Phenylephrine and Tropicamide during Accommodation Imaged with Ultralong Scan Depth Optical Coherence Tomography.

J Ophthalmol 2019 25;2019:6827215. Epub 2019 Feb 25.

Department of Ophthalmology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China.

Purpose: To investigate the influence of phenylephrine and tropicamide on anterior segment biometry with ultralong scan depth optical coherence tomography (UL-OCT) during accommodation.

Methods: In this study, 20 left eyes of healthy volunteers with a mean ± standard deviation age of 31.05 ± 5. Read More

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http://dx.doi.org/10.1155/2019/6827215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421770PMC
February 2019
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Unfolded Protein Response Pathways Correlatively Modulate Endoplasmic Reticulum Stress Responses in Rat Retinal Müller Cells.

J Ophthalmol 2019 24;2019:9028483. Epub 2019 Feb 24.

Department of Ophthalmology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, China.

Background: Endoplasmic reticulum stress (ERS) in the retinal Müller cells is a key factor contributing to the retinal inflammation and vascular leakage in diabetic retinopathy (DR). This study was to investigate the underlying mechanisms through which the 3 main unfolded protein response (UPR) pathways regulate ERS and to examine the expression levels of vascular endothelial growth factor (VEGF) in Müller cells .

Methods: Rat Müller cell lines were stimulated with high glucose to mimic a diabetic environment . Read More

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http://dx.doi.org/10.1155/2019/9028483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409019PMC
February 2019

Vitamins and Mineral Supplements for Retinitis Pigmentosa.

J Ophthalmol 2019 21;2019:8524607. Epub 2019 Feb 21.

Chengdu University of Traditional Chinese Medicine, 37 Twelve Bridge Road, Chengdu 610075, China.

Retinitis pigmentosa (RP) is a group of inherited progressive retinal dystrophies that is present with progressive vision loss, night blindness, visual field reduction, and retinal pigmentation of the fundus. RP is an uncommon but clinically important disease. It is progressive and potentially blinding, and to date, no cure for RP has been identified and clinical interventions to retard disease progression are limited. Read More

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http://dx.doi.org/10.1155/2019/8524607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409042PMC
February 2019

Corneal Endothelial Cell Density and Morphology in Healthy Egyptian Eyes.

J Ophthalmol 2019 24;2019:6370241. Epub 2019 Feb 24.

Egyptian Police Hospital, Sohag University, Sohag, Egypt.

Purpose: To evaluate the corneal endothelial cell density and morphology in normal Egyptian eyes.

Methods: In total, 568 healthy eyes of 568 Egyptian volunteers aged 20 to 85 years were examined using noncontact specular microscopy for the central corneal thickness (CCT), mean endothelial cell density (MCD), coefficient of variation (CV) in cell area, mean cell area (MCA), and hexagonal cell (Hex) percentage. Variables were compared between sexes and between different age groups. Read More

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http://dx.doi.org/10.1155/2019/6370241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409007PMC
February 2019

Perspectives of Autologous Mesenchymal Stem-Cell Transplantation in Macular Hole Surgery: A Review of Current Findings.

J Ophthalmol 2019 24;2019:3162478. Epub 2019 Feb 24.

S.C.U. Ophthalmology Unit, "City of Health and Science" University Hospital, Via Cherasco 23, 10126 Turin, Italy.

The main treatment available for idiopathic macular holes is represented by pars plana vitrectomy with internal limiting membrane peeling. However, late-stage macular holes are affected by a higher risk of surgical failure. Although adjuvant techniques can be employed, a satisfactory functional recovery is difficult to achieve in refractory macular holes. Read More

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http://dx.doi.org/10.1155/2019/3162478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409040PMC
February 2019

The Relationship between Carotid Intima-Media Thickness and Ocular Circulation in Type-2 Diabetes.

J Ophthalmol 2019 20;2019:3421305. Epub 2019 Feb 20.

Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.

Purpose: To compare clinical findings, including ocular blood flow and intima-media thickness (IMT) of the carotid artery, in mild nonproliferative diabetic retinopathy (NPDR) and no diabetic retinopathy (NDR) patients, and to determine risk factors contributing to mild NPDR.

Methods: In 129 subjects (129 eyes) with type-2 diabetes patients and mild NPDR or NDR, standard statistical techniques were used to determine associations between clinical findings, including diabetes duration, blood levels of creatinine and hemoglobin A1c (HbA1c), central macular thickness (CMT; measured with optical coherence tomography), mean blur rate (MBR; measured with laser speckle flowgraphy), and ultrasound-measured carotid IMT.

Results: Diabetes duration, IMT, and CMT were significantly higher in the mild NPDR patients than the NDR patients (=0. Read More

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http://dx.doi.org/10.1155/2019/3421305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402216PMC
February 2019

Identification of a Heterozygous Mutation in the Gene in a Hui-Chinese Family with Corneal Dystrophy.

J Ophthalmol 2019 19;2019:2824179. Epub 2019 Feb 19.

Center for Experimental Medicine, The Third Xiangya Hospital, Central South University, Changsha, China.

Background/aims: Corneal dystrophies (CDs) belong to a group of hereditary heterogeneous corneal diseases which result in visual impairment due to the progressive accumulation of deposits in different corneal layers. So far, mutations in several genes have been responsible for various CDs. The purpose of this study is to identify gene mutations in a three-generation Hui-Chinese family associated with granular corneal dystrophy type I (GCD1). Read More

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http://dx.doi.org/10.1155/2019/2824179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399521PMC
February 2019

Therapeutic Effect of Traditional Chinese Medicine on a Rat Model of Branch Retinal Vein Occlusion.

J Ophthalmol 2019 18;2019:9521379. Epub 2019 Feb 18.

Institute of Neurobiology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, Shaanxi 710061, China.

Branch retinal vein occlusion (BRVO) is a common retinal vascular disorder leading to visual impairment. Currently, the general strategies for BRVO are symptomatic therapies. Cardiovascular aspects are essential risk factors for BRVO. Read More

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http://dx.doi.org/10.1155/2019/9521379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398022PMC
February 2019

Quantitative Assessment of Outer Retinal Layer and Photoreceptor Outer Segment Layer and Their Relation to Visual Acuity in Diabetic Macular Edema.

J Ophthalmol 2019 17;2019:8216150. Epub 2019 Feb 17.

Assistant Professor of Ophthalmology, Ain Shams University, Cairo, Egypt.

Purpose: To compare outer retinal layer (ORL) thickness and photoreceptor outer segment (PROS) length between normal eyes and eyes with diabetic macular edema (DME), and also, to study the correlation between central macular thicknesses (CMT), ORL, and PROS length with best corrected visual acuity (BCVA) in DME.

Methods: 80 eyes were included in the study; they were divided into two groups, group Ι (40 normal eyes) and group ΙΙ (40 eyes) with DME. Complete ophthalmic examination and OCT were done for all eyes. Read More

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http://dx.doi.org/10.1155/2019/8216150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397985PMC
February 2019

Management of Corneal Ectasia after LASIK with Phototherapeutic Keratectomy Combined with Photorefractive Keratectomy and Collagen Cross-Linking.

J Ophthalmol 2019 18;2019:2707826. Epub 2019 Feb 18.

Department of Ophthalmology, Shandong Provincial Hospital Affiliated to Shandong University, No. 324 Jingwuweiqi Road, Jinan, Shandong, China.

Background: To evaluate the efficacy of phototherapeutic keratectomy (PTK) combined with photorefractive keratectomy (PRK) and riboflavin with ultraviolet-A collagen cross-linking (CXL), performed sequentially on the same day, in the management of corneal ectasia after LASIK.

Methods: This retrospective review comprised consecutive patients with corneal ectasia after LASIK. The patients were administered PTK and PRK on the previous corneal flap, and CXL was given on the same day by the same surgeon. Read More

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http://dx.doi.org/10.1155/2019/2707826DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397964PMC
February 2019
1 Read

Inpatient and Emergency Room Ophthalmology Consultations at a Tertiary Care Center.

J Ophthalmol 2019 14;2019:7807391. Epub 2019 Feb 14.

University of Illinois at Chicago, Department of Ophthalmology and Visual Sciences, Chicago, IL, USA.

Background: An ophthalmology consultation service is of significant benefit to patients in the hospital and is an instructive component of a residency education program. Ophthalmology consultations in a hospital present unique challenges to those seen in an outpatient clinic, for which the consulting ophthalmologist should be prepared. The purpose of this study was to profile the emergency room and inpatient ophthalmology consultations seen at an academic institution. Read More

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http://dx.doi.org/10.1155/2019/7807391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393906PMC
February 2019

Influence of Type 1 Diabetes Mellitus on the Ocular Biometry of Chinese Children.

J Ophthalmol 2019 14;2019:7216490. Epub 2019 Feb 14.

Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, No. 100, Haining Road, Shanghai 200080, China.

Purpose: To compare ocular biometry between children with type 1 diabetes mellitus (T1DM) and healthy children in China and to determine the correlation of ocular biometry with the glycosylated hemoglobin (HbA1c) level and diabetes duration.

Methods: A case-control study was conducted at Children's Hospital of Fudan University between T1DM children and healthy children. The participants were evaluated for central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), K1 and K2 keratometry, and axial length (AL); also cycloplegic refraction was performed, and spherical equivalent (SE) was acquired. Read More

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http://dx.doi.org/10.1155/2019/7216490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393916PMC
February 2019
2 Reads

Pachychoroid Pigment Epitheliopathy and Choroidal Thickness Changes in Coeliac Disease.

J Ophthalmol 2019 13;2019:6924191. Epub 2019 Feb 13.

University of Health Sciences, Okmeydani Training and Research Hospital, Department of Gastroenterology, Istanbul, Turkey.

Purpose: To evaluate choroidal thickness in patients with coeliac disease (CD) using spectral domain optical coherence tomography (SD-OCT) and to compare the results to normal eyes.

Methods: Seventy patients with CD and 70 healthy controls were included in this prospective, comparative study. All participants underwent a complete ophthalmologic evaluation and SD-OCT. Read More

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http://dx.doi.org/10.1155/2019/6924191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394117PMC
February 2019

Intraocular Foreign Bodies: Clinical Characteristics and Prognostic Factors Influencing Visual Outcome and Globe Survival in 373 Eyes.

J Ophthalmol 2019 13;2019:5208092. Epub 2019 Feb 13.

Eye Center, The Second Hospital of Jilin University, 218 Ziqiang Street, Changchun, Jilin 130021, China.

Aim: To describe epidemiologic and clinical characteristics and prognostic factors influencing visual outcome after intraocular foreign bodies (IOFBs) injury.

Methods: Medical records of 370 patients (373 eyes) with IOFBs were reviewed to identify the factors influencing visual acuity by univariate and multivariate analyses.

Results: The majority of patients (97. Read More

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http://dx.doi.org/10.1155/2019/5208092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393895PMC
February 2019
2 Reads

Clinicopathological Review of 547 Bulbar Enucleations in Hungary (2006-2017).

J Ophthalmol 2019 14;2019:2042459. Epub 2019 Feb 14.

Department of Ophthalmology, Semmelweis University, Budapest, Hungary.

Purpose: To analyse current clinicopathological enucleation indications in a large third-referral centre in a developed country (Hungary) over a period of 12 years.

Methods: Retrospective review was performed on 547 enucleated eyes of 543 patients (48.6% males, age 52. Read More

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http://dx.doi.org/10.1155/2019/2042459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393907PMC
February 2019
1 Read

Horizontal Saccadic Velocity in Patients with Exotropia before and after Unilateral Resection and Recession Surgery.

J Ophthalmol 2019 13;2019:1374917. Epub 2019 Feb 13.

Department of Integrative Neuroscience, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan.

Purpose: The effects of strabismus surgery on eye movement are not known in detail, as few studies have compared saccade velocities before and after strabismus surgery. In this study, horizontal saccades were recorded using an eye-tracker in patients with only exotropia to compare the peak velocities (PVs), before and after undergoing strabismus surgery of the same type (unilateral resection and recession).

Methods: Horizontal saccades of monocular vision were recorded using an eye-tracking device in 18 patients with exotropia and 20 normal subjects. Read More

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http://dx.doi.org/10.1155/2019/1374917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393912PMC
February 2019

Comparison between Refractive Outcome of Primary Piggyback Intraocular Lens versus Secondary Lens Iris Claw Lens in Posterior Microphthalmos.

J Ophthalmol 2019 14;2019:1356982. Epub 2019 Feb 14.

Ophthalmology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt.

Purpose: To compare the refractive outcome of 2 different methods of intraocular lens implantation in cases of posterior microphthalmos, primary piggyback IOLs versus secondary iris claw lenses.

Methods: This study was a retrospective interventional comparative study that included 60 eyes of 30 patients. The included patients had bilateral microphthalmos with high axial hyperopia and had undergone a lens-based surgical procedure for hyperopia correction. Read More

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http://dx.doi.org/10.1155/2019/1356982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393898PMC
February 2019

Fundus Autofluorescence in Lamellar Macular Holes and Pseudoholes: A Review.

J Ophthalmol 2019 10;2019:4948212. Epub 2019 Feb 10.

Eye Clinic, Department of Clinical Science "Luigi Sacco", Sacco Hospital, University of Milan, Milan, Italy.

Macular pseudoholes (MPHs) and lamellar macular holes (LMHs) have been recently defined according to spectral domain optical coherence tomography (SD-OCT) criteria. A major feature for differentiating an MPH from an LMH remains the loss of foveal tissue. The anatomy of the foveola is peculiar with the macular pigment (MP) embedded in a very thin layer of tissue underlying the internal limiting membrane and mainly constituted of a specialized group of Müller cells and Henle's fibers. Read More

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http://dx.doi.org/10.1155/2019/4948212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387722PMC
February 2019

The Effect of Maxim Eye Drops on Morphology and Apoptosis in Lacrimal Gland of Experimental Dry Eye Rabbit Model.

J Ophthalmol 2019 5;2019:5916243. Epub 2019 Feb 5.

The Domestic First-class Discipline Construction Project of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan Province 410208, China.

The purpose of this study was to investigate the effects of Maxim eye drops on morphology and apoptosis in lacrimal glands of the experimental dry eye rabbit model. A total of thirty-six male rabbits were divided into six study groups, consisting of the control group and the dry eye rabbit model group (without any treatment), the dry eye rabbit model group treated with testosterone, and the dry eye rabbit model group treated with different concentrations of Maxim eye drops (1.0 mg/ml, 1. Read More

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https://www.hindawi.com/journals/joph/2019/5916243/
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http://dx.doi.org/10.1155/2019/5916243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379849PMC
February 2019
4 Reads

Bioresorbable Material in Secondary Orbital Reconstruction Surgery.

J Ophthalmol 2019 3;2019:8715314. Epub 2019 Feb 3.

Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Purpose: To validate the potential of bioresorbable implantation in secondary revisional reconstruction after inadequate primary orbital fracture repair, with assessment of pre- and postoperative clinical characteristics and computed tomography image findings.

Methods: A retrospective chart review was conducted on 16 consecutive patients treated for orbital fractures at Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, with inadequate prior surgeries between July 2010 and June 2017; patients who had suffered orbital blowout fractures had undergone primary surgeries elsewhere. Secondary repair of orbital fractures used bioresorbable material following unsatisfactory primary orbital repair. Read More

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https://www.hindawi.com/journals/joph/2019/8715314/
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http://dx.doi.org/10.1155/2019/8715314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377963PMC
February 2019
2 Reads

The Management of Retinal Detachment: Techniques and Perspectives 2018.

J Ophthalmol 2019 3;2019:8185619. Epub 2019 Feb 3.

Department of Ophthalmology & Vision Science, University of California Davis Eye Center, Sacramento, CA, USA.

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http://dx.doi.org/10.1155/2019/8185619DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377983PMC
February 2019
3 Reads

-rs12536657 and Ocular Biometric Parameters in Hyperopic Children, Emmetropic Adolescents, and Young Adults: A Multicenter Quantitative Trait Study.

J Ophthalmol 2019 3;2019:7454250. Epub 2019 Feb 3.

Department of Pediatrics and Clinical Genetics Unit, Clínica Universidad de Navarra, Navarra Institute for Health Research (IdiSNA), 31008 Pamplona, Spain.

Introduction: Even though ocular refractive state is highly heritable and under strong genetic control, the identification of susceptibility genes remains a challenge. Several (hepatocyte growth factor) gene variants have been associated with ocular refractive errors and corneal pathology.

Purpose: Here, we assess the association of an gene variant, previously reported as associated with hyperopia, and ocular biometric parameters in a multicenter Spanish cohort. Read More

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http://dx.doi.org/10.1155/2019/7454250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378066PMC
February 2019
1 Read

Management and Microbiological Characteristics of Membrane Formation on a Hydrophilic Acrylic Intraocular Lens: A Clinical Case Series and Material Comparative Study of Different IOLs.

J Ophthalmol 2019 3;2019:5746186. Epub 2019 Feb 3.

Eye Institute, Eye, Ear, Nose, and Throat Hospital of Fudan University, 83 Fenyang Road, Shanghai 200031, China.

/. To report a case series of membrane formation on intraocular lenses (IOLs) after uneventful phacoemulsification and to evaluate the material characteristics and biofilm formation on different IOLs. . Read More

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http://dx.doi.org/10.1155/2019/5746186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377987PMC
February 2019
2 Reads

Twenty-Four-Hour Contact Lens Sensor Monitoring of Aqueous Humor Dynamics in Surgically or Medically Treated Glaucoma Patients.

J Ophthalmol 2019 27;2019:9890831. Epub 2019 Jan 27.

Ophthalmology, Department of Surgical, Medical, Molecular Pathology and of Critical Area, University of Pisa, Pisa, Italy.

Aim: This study assessed the 24 h circadian rhythm of intraocular pressure (IOP) using a contact lens sensor in three groups of patients with open-angle glaucoma.

Methods: This study was a monocentric, cross-sectional, nonrandomized, prospective, pilot study. Eighty-nine patients were enrolled: 29 patients previously underwent an Ex-PRESS mini glaucoma device procedure (Group 1), 28 patients previously underwent Hydrus microstent implantation (Group 2), and 32 patients were currently being treated medically for primary open-angle glaucoma (Group 3). Read More

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http://dx.doi.org/10.1155/2019/9890831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369465PMC
January 2019
4 Reads
1.935 Impact Factor

Nd:YAG Laser Vitreolysis for Symptomatic Vitreous Floaters: Application of Infrared Fundus Photography in Assessing the Treatment Efficacy.

J Ophthalmol 2019 27;2019:8956952. Epub 2019 Jan 27.

Shandong Eye Hospital, Shandong Eye Institute, Shandong Academy of Medical Sciences, Jinan 250021, Shandong, China.

Background: Vitreous floater is a physically common phenomenon with aging and is related to visual impairment and decrease of quality of life. Nd:YAG vitreolysis is supposed to be an option for resolving floaters, but its clinical efficacy is undefined. We aimed to evaluate the efficacy of Nd:YAG vitreolysis in treating floater semiquantifiably by determining changes of floater areas on infrared fundus photography (IR). Read More

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http://dx.doi.org/10.1155/2019/8956952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369481PMC
January 2019
5 Reads

The Study of a New Modified Bicanalicular Intubation for the Repairment of Traumatic Canalicular Laceration.

J Ophthalmol 2019 27;2019:8435185. Epub 2019 Jan 27.

Department of Ophthalmology, The Second People's Hospital of Jinan, 148# Jingyi Road, Jinan 250001, China.

Introduction: To investigate the efficacy and safety of a modified bicanalicular intubation (MBCI) used in canalicular laceration.

Materials And Methods: This study is a retrospective consecutive chart review. A total of 43 eyes from 43 patients (36 males and 7 females) who underwent canalicular intubation were enrolled. Read More

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http://dx.doi.org/10.1155/2019/8435185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369491PMC
January 2019
2 Reads

Early Refractive and Clinical Outcomes of High-Myopic Photorefractive Keratectomy as an Alternative to LASIK Surgery in Eyes with High Preoperative Percentage of Tissue Altered.

J Ophthalmol 2019 28;2019:6513143. Epub 2019 Jan 28.

Department of Ophthalmology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Objective: To analyze the safety and efficacy of high-myopic PRK as an alternative to LASIK surgery in patients with a high preoperative percentage tissue altered (PTA).

Design: Retrospective interventional case series.

Participants: Charts of 256 consecutive eyes that underwent PRK with application of mitomycin-C 0. Read More

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http://dx.doi.org/10.1155/2019/6513143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369480PMC
January 2019
2 Reads

COL11A1 Polymorphisms Are Associated with Primary Angle-Closure Glaucoma Severity.

J Ophthalmol 2019 27;2019:2604386. Epub 2019 Jan 27.

Department of Ophthalmology & Visual Science, Eye & ENT Hospital, Shanghai Medical College, Fudan University, Shanghai 200032, China.

Purpose: PLEKHA7 and COL11A1 were genotyped for single-nucleotide polymorphisms (SNPs) to investigate the possible association of these two genes with primary angle-closure glaucoma (PACG) and disease severity.

Method: A total of 51 PACG cases and 51 normal controls were recruited. Twelve SNPs in the PLEKHA7 (rs216489, rs1027617, rs366590, rs11024060, rs6486330, rs11024097, and rs11024102) and COL11A1 (rs1676484, rs3753841, rs12138977, rs2126642, and rs2622848) genes were genotyped by direct Sanger sequencing. Read More

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http://dx.doi.org/10.1155/2019/2604386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369458PMC
January 2019
2 Reads

The Role of Connexin-43 in the Inflammatory Process: A New Potential Therapy to Influence Keratitis.

J Ophthalmol 2019 21;2019:9312827. Epub 2019 Jan 21.

Department of Ophthalmology, China-Japan Union Hospital of Jilin University, Changchun 130033, Jilin Province, China.

The studies outlined in this review highlight the relationship between inflammatory signaling molecules and connexin-43 (Cx43). Gap junction (GJ) channels and hemichannels (HCs) participate in the metabolic activity between intra- and extracellular space. Some ions and small molecules are exchanged from cell to cell or cell to extracellular space to affect the process of inflammation via GJ. Read More

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http://dx.doi.org/10.1155/2019/9312827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360563PMC
January 2019
3 Reads

Analysis of Gene Mutations in Three Chinese Families with Corneal Dystrophy.

J Ophthalmol 2019 22;2019:6769013. Epub 2019 Jan 22.

Department of Ophthalmology, Taizhou Municipal Hospital, Taizhou University, Taizhou, China.

Objective: To identify the types of (transforming growth factor, beta-induced) gene mutations in three Chinese families with Reis-Bücklers corneal dystrophy (RBCD), lattice corneal dystrophy type I (LCDI), or Avellino corneal dystrophy (ACD) and to investigate the relationship between the phenotypes and genotypes of corneal dystrophy.

Methods: Peripheral blood was collected from 24 patients and 76 phenotypically normal members in three Chinese families as well as from 100 healthy controls. Genomic DNA was extracted. Read More

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http://dx.doi.org/10.1155/2019/6769013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362487PMC
January 2019
2 Reads

Increased Subfoveal Choroidal Thickness and Retinal Structure Changes on Optical Coherence Tomography in Pediatric Alport Syndrome Patients.

J Ophthalmol 2019 21;2019:6741930. Epub 2019 Jan 21.

Tepecik Research and Training Hospital, Ophthalmology Department, Izmir, Turkey.

Objective: To evaluate optical coherence tomography (OCT) findings of pediatric Alport syndrome (AS) patients with no retinal pathology on fundus examination.

Materials And Methods: Twenty-one patients being followed up with the diagnosis of AS (Group 1) and 24 age- and sex-matched healthy volunteers (Group 2) were prospectively evaluated. All participants underwent standard ophthalmologic examination, retinal nerve fibre layer (RNFL) analysis, and horizontal and vertical scan macula enhanced depth imaging OCT (EDI-OCT). Read More

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http://dx.doi.org/10.1155/2019/6741930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360616PMC
January 2019
3 Reads

The Influence of Overnight Orthokeratology on Ocular Surface and Meibomian Gland Dysfunction in Teenagers with Myopia.

J Ophthalmol 2019 21;2019:5142628. Epub 2019 Jan 21.

Tianjin Medical University Eye Hospital, Tianjin Medical University Eye Institute, College of Optometry and Ophthalmology, Tianjin Medical University, Fukang Rd. 251, Nankai District, Tianjin 300384, China.

Purpose: The aim of this study was to investigate the effect of overnight orthokeratology (OOK) on ocular surface and meibomian gland dysfunction in teenagers with myopia.

Methods: A total of 59 subjects were recruited in this prospective study. The following tests were performed before and after 1, 3, 6, 12, and 24 months of OOK lens wear, including ocular surface disease index (OSDI) questionnaire, slit-lamp examination, and Keratograph 5M. Read More

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http://dx.doi.org/10.1155/2019/5142628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360595PMC
January 2019
8 Reads

Internal Limiting Membrane Flap in the Management of Retinal Detachment due to Paracentral Retinal Breaks.

J Ophthalmol 2019 21;2019:4303056. Epub 2019 Jan 21.

Department of Ophthalmology, Changhua Christian Hospital, Changhua, Taiwan.

Purpose: To describe the technique and outcomes of using either inverted or free internal limiting membrane flap in the management of retinal detachment due to paracentral retinal breaks.

Methods: This retrospective observational case series includes nine patients who received surgery for retinal detachment due to paracentral retinal breaks developed either from primary rhegmatogenous origin, or secondary iatrogenic retinal breaks after prior membrane peeling, or during surgery for tractional retinal detachment. Either inverted or free internal limiting membrane flaps were inserted in the identified breaks, followed by air fluid exchange and gas tamponade. Read More

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http://dx.doi.org/10.1155/2019/4303056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360606PMC
January 2019
3 Reads

Epiretinal Membrane Surgery in Daily Clinical Practice: Results of a Proposed Management Scheme.

J Ophthalmol 2019 10;2019:8246858. Epub 2019 Jan 10.

Clínica Rementería, Madrid, Spain.

Purpose: To report the results of the epiretinal membrane (ERM) management guidelines followed in our center.

Methods: Patients with ERM seen between 2014 and 2015, with ≥2 years follow-up or who had undergone ERM surgery, were included. Corrected visual acuity (VA), lens status, and ERM configuration were recorded at each visit. Read More

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http://dx.doi.org/10.1155/2019/8246858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350604PMC
January 2019
2 Reads

The Effects of Diabetic Duration on Lacrimal Functional Unit in Patients with Type II Diabetes.

J Ophthalmol 2019 10;2019:8127515. Epub 2019 Jan 10.

Tianjin Medical University Eye Hospital, Tianjin Medical University Eye Institute, College of Optometry and Ophthalmology, Tianjin Medical University, Tianjin 300384, China.

Purpose: To observe ocular surface changes in Type II diabetic patients with different disease durations and to understand the correlations between clinical parameters and diabetic durations.

Methods: In this cross-sectional, prospective study, 51 healthy controls and 91 patients with Type II diabetes were enrolled. The diabetics were divided into 3 subgroups according to the disease duration, including duration <10 y group, 10 to 20 y group, and ≥21 y group. Read More

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http://dx.doi.org/10.1155/2019/8127515DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350560PMC
January 2019
4 Reads
1.935 Impact Factor

Early Macular Angiography among Patients with Glaucoma, Ocular Hypertension, and Normal Subjects.

J Ophthalmol 2019 15;2019:7419470. Epub 2019 Jan 15.

Department of Ophthalmology, Show Chwan Memorial Hospital, Changhua, Taiwan.

Purpose: To evaluate early macular circulation in open-angle glaucoma (OAG), normal-tension glaucoma (NTG), ocular hypertension (OHT), and healthy subjects via optical coherence tomography angiography (OCTA).

Methods: A retrospective cross-sectional study was conducted. Medical records were reviewed, and the patients who received OCTA examinations were divided into the OAG, NTG, OHT, and normal groups. Read More

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http://dx.doi.org/10.1155/2019/7419470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350555PMC
January 2019
4 Reads

The Association of Oxidative Stress Status with Open-Angle Glaucoma and Exfoliation Glaucoma: A Systematic Review and Meta-Analysis.

J Ophthalmol 2019 15;2019:1803619. Epub 2019 Jan 15.

Department of Clinical Laboratory, Eye & ENT Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

Purpose: To systematically evaluate the associations between oxidative stress status and different types of glaucoma.

Design: Systematic review and meta-analysis.

Methods: We searched PubMed, EMBASE, and the Web of Science for randomized controlled trials written in the English language between January 1, 1990, and November 30, 2016. Read More

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http://dx.doi.org/10.1155/2019/1803619DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350588PMC
January 2019
3 Reads

Long-Term Clinical Outcomes after Mix and Match Implantation of Two Multifocal Intraocular Lenses with Different Adds.

J Ophthalmol 2019 14;2019:6789263. Epub 2019 Jan 14.

Tianjin Medical University Eye Hospital, Tianjin Medical University Eye Institute & Tianjin Medical University School of Optometry and Ophthalmology, No. 251, Fukang Road, Nankai District, Tianjin 300384, China.

Purpose: To compare long-term clinical outcomes between patients with bilateral implantation of +3.0 diopter (D) multifocal intraocular lenses (IOLs) and mix and match implantation of +2.5 D and +3. Read More

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http://dx.doi.org/10.1155/2019/6789263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348908PMC
January 2019
4 Reads
1.935 Impact Factor