7,708 results match your criteria Journal of Magnetic Resonance Imaging[Journal]


Optimization and Repeatability of Multipool Chemical Exchange Saturation Transfer MRI of the Prostate at 3.0 T.

J Magn Reson Imaging 2019 Feb 15. Epub 2019 Feb 15.

Centre for Medical Imaging, University College London, London, UK.

Background: Chemical exchange saturation transfer (CEST) can potentially support cancer imaging with metabolically derived information. Multiparametric prostate MRI has improved diagnosis but may benefit from additional information to reduce the need for biopsies.

Purpose: To optimize an acquisition and postprocessing protocol for 3. Read More

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http://dx.doi.org/10.1002/jmri.26690DOI Listing
February 2019

Autoregressive Moving Average Modeling for Hepatic Iron Quantification in the Presence of Fat.

J Magn Reson Imaging 2019 Feb 13. Epub 2019 Feb 13.

Department of Diagnostic Imaging, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

Background: Measuring hepatic R2* by fitting a monoexponential model to the signal decay of a multigradient-echo (mGRE) sequence noninvasively determines hepatic iron content (HIC). Concurrent hepatic steatosis introduces signal oscillations and confounds R2* quantification with standard monoexponential models.

Purpose: To evaluate an autoregressive moving average (ARMA) model for accurate quantification of HIC in the presence of fat using biopsy as the reference. Read More

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http://dx.doi.org/10.1002/jmri.26682DOI Listing
February 2019

Reference range determination for imaging biomarkers: Myocardial T.

J Magn Reson Imaging 2019 Feb 12. Epub 2019 Feb 12.

School of Health Sciences, University of Manchester, UK.

Background: Imaging biomarkers, such as the T relaxation time of the myocardium using MRI, can be valuable in cardiac medicine if they are properly validated. Consensus statements recommend that for myocardial T , each investigator should establish a reference range.

Purpose: To describe a statistically valid method for determining and reporting the reference range in each center, which simultaneously minimizes the twin risks of undersampling, leading to a uselessly uncertain range, and oversampling, which exposes volunteers to unnecessary scanning and wastes resources. Read More

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http://dx.doi.org/10.1002/jmri.26683DOI Listing
February 2019

Highly-accelerated volumetric brain examination using optimized wave-CAIPI encoding.

J Magn Reson Imaging 2019 Feb 8. Epub 2019 Feb 8.

Department of Radiology, A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, USA.

Background: Rapid volumetric imaging protocols could better utilize limited scanner resources.

Purpose: To develop and validate an optimized 6-minute high-resolution volumetric brain MRI examination using Wave-CAIPI encoding.

Study Type: Prospective. Read More

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http://dx.doi.org/10.1002/jmri.26678DOI Listing
February 2019

Paraspinal Muscle DTI Metrics Predict Muscle Strength.

J Magn Reson Imaging 2019 Feb 5. Epub 2019 Feb 5.

Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.

Background: The paraspinal muscles play an important role in the onset and progression of lower back pain. It would be of clinical interest to identify imaging biomarkers of the paraspinal musculature that are related to muscle function and strength. Diffusion tensor imaging (DTI) enables the microstructural examination of muscle tissue and its pathological changes. Read More

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http://dx.doi.org/10.1002/jmri.26679DOI Listing
February 2019
1 Read

Na MRI Depicts Early Changes in Ion Homeostasis in Skeletal Muscle Tissue of Patients With Duchenne Muscular Dystrophy.

J Magn Reson Imaging 2019 Feb 4. Epub 2019 Feb 4.

Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.

Background: Duchenne muscular dystrophy (DMD) is a hereditary neuromuscular disease leading to progressive muscle wasting. Since there is a need for MRI variables that serve as early sensitive indicators of response to treatment, several quantitative MRI methods have been suggested for disease monitoring.

Purpose: To evaluate the potential of sodium ( Na) and proton ( H) MRI methods to assess early pathological changes in skeletal muscle of DMD. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/jmri.26681
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http://dx.doi.org/10.1002/jmri.26681DOI Listing
February 2019
5 Reads

Analysis of aortic pressure fields from 4D flow MRI in healthy volunteers: Associations with age and left ventricular remodeling.

J Magn Reson Imaging 2019 Feb 4. Epub 2019 Feb 4.

Sorbonne Université, INSERM, CNRS, Laboratoire d'Imagerie Biomédicale, Paris, France.

Background: Aging-related arterial stiffness is associated with substantial changes in global and local arterial pressures. The subsequent early return of reflected pressure waves leads to an elevated left ventricular (LV) afterload and ultimately to a deleterious concentric LV remodeling.

Purpose: To compute aortic time-resolved pressure fields of healthy subjects from 4D flow MRI and to define relevant pressure-based markers while investigating their relationship with age, LV remodeling, as well as tonometric augmentation index (AIx) and pulse wave velocity (PWV). Read More

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http://dx.doi.org/10.1002/jmri.26673DOI Listing
February 2019

Elevated diastolic wall shear stress in regurgitant semilunar valvular lesions.

J Magn Reson Imaging 2019 Feb 4. Epub 2019 Feb 4.

Pediatric Cardiology and Congenital Heart Disease, German Heart Center at Technical University of Munich, Munich, Germany.

Background: Alterations in wall shear stress (WSS) assessed using 4D flow MRI have been shown to play a role in various vascular pathologies, such as bicuspid aortic valve aortopathy. Most studies have focused on systolic WSS, whereas altered diastolic hemodynamics in regurgitant semilunar valvular lesions have not so far been well characterized.

Purpose: To investigate diastolic WSS in aortic and pulmonary regurgitation. Read More

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http://dx.doi.org/10.1002/jmri.26680DOI Listing
February 2019
1 Read

Intravoxel incoherent motion MRI for discrimination of synovial proliferation in the hand arthritis: A prospective proof-of-concept study.

J Magn Reson Imaging 2019 Jan 31. Epub 2019 Jan 31.

Faculty of Health Sciences, Hokkaido University, Sapporo, Japan.

Background: Postcontrast-enhanced MRI is currently the reference standard for synovial proliferation in rheumatoid arthritis (RA). However, the technique is somewhat invasive due to the use of gadolinium contrast agents, which may cause severe adverse/side effects. Intravoxel incoherent motion (IVIM) simultaneously permits quantification of perfusion as well as diffusion using a single imaging scan. Read More

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http://dx.doi.org/10.1002/jmri.26660DOI Listing
January 2019

Transition zone prostate cancer: Logistic regression and machine-learning models of quantitative ADC, shape and texture features are highly accurate for diagnosis.

J Magn Reson Imaging 2019 Jan 30. Epub 2019 Jan 30.

Department of Medical Imaging, Ottawa Hospital, University of Ottawa, Ontario, Canada.

Background: The limitation of diagnosis of transition zone (TZ) prostate cancer (PCa) using subjective assessment of multiparametric (mp) MRI with PI-RADS v2 is related to overlapping features between cancers and stromal benign prostatic hyperplasia (BPH) nodules, particularly in small lesions.

Purpose: To evaluate modeling of quantitative apparent diffusion coefficient (ADC), texture, and shape features using logistic regression (LR) and support vector machine (SVM) models for the diagnosis of transition zone PCa.

Study Type: Retrospective. Read More

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http://dx.doi.org/10.1002/jmri.26674DOI Listing
January 2019

MRI biomarkers in osseous tumors.

J Magn Reson Imaging 2019 Jan 30. Epub 2019 Jan 30.

Department of Radiology, Stony Brook University, Stony Brook, New York, USA.

Although radiography continues to play a critical role in osseous tumor assessment, there have been remarkable advances in cross-sectional imaging. MRI has taken a lead in this assessment due to high tissue contrast and spatial resolution, which are well suited for bone lesion assessment. More recently, although somewhat lagging other organ systems, quantitative parameters have shown promising potential as biomarkers for osseous tumors. Read More

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http://dx.doi.org/10.1002/jmri.26672DOI Listing
January 2019

Water-fat separation and parameter mapping in cardiac MRI via deep learning with a convolutional neural network.

J Magn Reson Imaging 2019 Jan 30. Epub 2019 Jan 30.

Department of Research and Education, Saint Francis Hospital, Roslyn, New York, USA.

Background: Water-fat separation is a postprocessing technique most commonly applied to multiple-gradient-echo magnetic resonance (MR) images to identify fat, provide images with fat suppression, and to measure fat tissue concentration. Recently, Numerous advancements have been reported. In contrast to early methods, the process of water-fat separation has become complicated due to multiparametric analytic models, optimization methods, and the absence of a unified framework for diverse source data. Read More

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http://doi.wiley.com/10.1002/jmri.26658
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http://dx.doi.org/10.1002/jmri.26658DOI Listing
January 2019
3 Reads

Pilot study on longitudinal change in pancreatic proton density fat fraction during a weight-loss surgery program in adults with obesity.

J Magn Reson Imaging 2019 Jan 30. Epub 2019 Jan 30.

Liver Imaging Group, Department of Radiology, University of California, San Diego School of Medicine, La Jolla, California, USA.

Background: Quantitative-chemical-shift-encoded (CSE)-MRI methods have been applied to the liver. The feasibility and potential utility CSE-MRI in monitoring changes in pancreatic proton density fat fraction (PDFF) have not yet been demonstrated.

Purpose: To use quantitative CSE-MRI to estimate pancreatic fat changes during a weight-loss program in adults with severe obesity and nonalcoholic fatty liver disease (NAFLD). Read More

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http://dx.doi.org/10.1002/jmri.26671DOI Listing
January 2019

MRI in pregnancy: Indications and practical considerations.

J Magn Reson Imaging 2019 Mar 31;49(3):621-631. Epub 2019 Jan 31.

Division of Abdominal Imaging, University of North Carolina Department of Radiology, Chapel Hill, North Carolina, USA.

There is a constantly evolving knowledgebase regarding the safety of MRI in pregnant patients, as well as the safety of gadolinium administration, given potential fetal risks. This review provides an overview of national and international recommendations for patient screening and safety by trimester, evaluates the most recent literature regarding administration of gadolinium in pregnant patients, and discusses technical requirements when imaging pregnant patients. A protocol for imaging pregnant patients is provided, and multiple common indications for MRI in pregnancy are discussed. Read More

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http://dx.doi.org/10.1002/jmri.26317DOI Listing

Associations between vertebral body fat fraction and intervertebral disc biochemical composition as assessed by quantitative MRI.

J Magn Reson Imaging 2019 Jan 30. Epub 2019 Jan 30.

Department of Orthopedic Surgery, University of California San Francisco, San Francisco, California, USA.

Background: There is an interplay between the intervertebral disc (IVD) and the adjacent bone marrow that may play a role in the development of IVD degeneration and might influence chronic lower back pain (CLBP).

Purpose: To apply novel quantitative MRI techniques to assess the relationship between vertebral bone marrow fat (BMF) and biochemical changes in the adjacent IVD.

Study Type: Prospective. Read More

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http://doi.wiley.com/10.1002/jmri.26675
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http://dx.doi.org/10.1002/jmri.26675DOI Listing
January 2019
2 Reads

Sensorineural hearing loss and cognitive impairments: Contributions of thalamus using multiparametric MRI.

J Magn Reson Imaging 2019 Jan 29. Epub 2019 Jan 29.

Jiangsu Key Laboratory of Molecular Imaging and Functional Imaging, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China.

Background: The thalamus is an integrative hub conveying sensory information between cortical areas and related to cognition. However, alterations of the thalamus following partial hearing deprivation remains unknown.

Purpose: To investigate the modifications of the thalamus and its seven subdivisions in terms of structure, function, and perfusion in subjects with sensorineural hearing loss (SNHL), as well as their associations with SNHL-induced cognitive impairments. Read More

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http://doi.wiley.com/10.1002/jmri.26665
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http://dx.doi.org/10.1002/jmri.26665DOI Listing
January 2019
5 Reads
3.210 Impact Factor

Evaluation of the distribution and progression of intraluminal thrombus in abdominal aortic aneurysms using high-resolution MRI.

J Magn Reson Imaging 2019 Jan 29. Epub 2019 Jan 29.

Department of Radiology and Biomedical Imaging, UCSF, San Francisco, California, USA.

Background: Intraluminal thrombus (ILT) signal intensity on MRI has been studied as a potential marker of abdominal aortic aneurysm (AAA) progression.

Purpose: 1) To characterize the relationship between ILT signal intensity and AAA diameter; 2) to evaluate ILT change over time; and 3) to assess the relationship between ILT features and AAA growth.

Study Type: Prospective. Read More

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http://dx.doi.org/10.1002/jmri.26676DOI Listing
January 2019
1 Read

Renal and adrenal masses containing fat at MRI: Proposed nomenclature by the society of abdominal radiology disease-focused panel on renal cell carcinoma.

J Magn Reson Imaging 2019 Jan 28. Epub 2019 Jan 28.

Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts, USA.

This article proposes a consensus nomenclature for fat-containing renal and adrenal masses at MRI to reduce variability, improve understanding, and enhance communication when describing imaging findings. The MRI appearance of "macroscopic fat" occurs due to a sufficient number of aggregated adipocytes and results in one or more of: 1) intratumoral signal intensity (SI) loss using fat-suppression techniques, or 2) chemical shift artifact of the second kind causing linear or curvilinear India-ink (etching) artifact within or at the periphery of a mass at macroscopic fat-water interfaces. "Macroscopic fat" is most commonly observed in adrenal myelolipoma and renal angiomyolipoma (AML) and only rarely encountered in other adrenal cortical tumors and renal cell carcinomas (RCC). Read More

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http://dx.doi.org/10.1002/jmri.26542DOI Listing
January 2019
2 Reads

MRI breast screening revisited.

J Magn Reson Imaging 2019 Jan 28. Epub 2019 Jan 28.

Department of Radiology, NYU School of Medicine, New York, New York, USA.

Contrast-enhanced breast MRI is a standard evidence-based component of supplemental screening in conjunction with mammography for higher-risk populations because of its high sensitivity for detecting breast cancer; the use of breast MRI for screening in high-risk populations is recommended in multiple national and international guidelines. The current MRI exam, however, is expensive relative to other screening technologies such as mammography, and relatively more time-intensive. Recent investigations have focused on techniques that have the potential for improving efficiency of the breast MRI exam, decreasing acquisition and reading times, without impacting diagnostic accuracy. Read More

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http://dx.doi.org/10.1002/jmri.26547DOI Listing
January 2019
1 Read

3D-T prepared zero echo time-based PETRA sequence for in vivo biexponential relaxation mapping of semisolid short-T tissues at 3 T.

J Magn Reson Imaging 2019 Jan 28. Epub 2019 Jan 28.

Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, New York, USA.

Background: In addition to the articular cartilage, osteoarthritis (OA) affects several other tissues such as tendons, ligaments, and subchondral bone. T1 relaxation study of these short T tissues may provide a more comprehensive evaluation of OA.

Purpose: To develop a 3D spin-lattice relaxation in the rotating frame (T ) prepared zero echo time (ZTE)-based pointwise encoding time reduction with radial acquisition (3D-T -PETRA) sequence for relaxation mapping of semisolid short-T tissues on a clinical 3 T scanner. Read More

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http://dx.doi.org/10.1002/jmri.26664DOI Listing
January 2019

Assessing the performance of benign and malignant breast lesion classification with bilateral TIC differentiation and other effective features in DCE-MRI.

J Magn Reson Imaging 2019 Jan 28. Epub 2019 Jan 28.

Sino-Dutch Biomedical and Information Engineering School, Northeastern University, Shenyang, China.

Background: Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is increasingly being used to detect and diagnose breast cancer. However, the effective methods based on quantitative feature analysis need to be explored.

Purpose: To investigate a new approach for improving the performance of benign and malignant breast lesion classification by combining bilateral time-intensity curve (TIC) differentiation features with other effective features. Read More

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http://dx.doi.org/10.1002/jmri.26646DOI Listing
January 2019
3.210 Impact Factor

Quantitative myocardial perfusion in coronary artery disease: A perfusion mapping study.

J Magn Reson Imaging 2019 Jan 25. Epub 2019 Jan 25.

University College London, Institute of Cardiovascular Science, London, UK.

Background: Cardiac MR stress perfusion remains a qualitative technique in clinical practice due to technical and postprocessing challenges. However, automated inline perfusion mapping now permits myocardial blood flow (MBF, ml/g/min) quantification on-the-fly without user input.

Purpose: To investigate the diagnostic performance of this novel technique in detecting occlusive coronary artery disease (CAD) in patients scheduled to undergo coronary angiography. Read More

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http://dx.doi.org/10.1002/jmri.26668DOI Listing
January 2019
2 Reads

Differentiating supraclavicular from gluteal adipose tissue based on simultaneous PDFF and T * mapping using a 20-echo gradient-echo acquisition.

J Magn Reson Imaging 2019 Jan 25. Epub 2019 Jan 25.

Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.

Background: Adipose tissue (AT) can be classified into white and brown/beige subtypes. Chemical shift encoding-based water-fat MRI-techniques allowing simultaneous mapping of proton density fat fraction (PDFF) and T * result in a lower PDFF and a shorter T * in brown compared with white AT. However, AT T * values vary widely in the literature and are primarily based on 6-echo data. Read More

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http://dx.doi.org/10.1002/jmri.26661DOI Listing
January 2019
3 Reads

Absence of dentate nucleus resting-state functional connectivity changes in nonneurological patients with gadolinium-related hyperintensity on T -weighted images.

J Magn Reson Imaging 2019 Jan 25. Epub 2019 Jan 25.

Departmental Faculty of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.

Background: The dentate nuclei of the cerebellum are the areas where gadolinium predominantly accumulates. It is not yet known whether gadolinium deposition affects brain functions.

Purpose/hypothesis: To assess whether gadolinium-dependent high signal intensity of the cerebellum on T -weighted images of nonneurological adult patients with Crohn's disease is associated with modifications of resting-state functional connectivity (RSFC) of the cerebellum and dentate nucleus. Read More

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http://dx.doi.org/10.1002/jmri.26669DOI Listing
January 2019
9 Reads

Na Triple-quantum signal of in vitro human liver cells, liposomes, and nanoparticles: Cell viability assessment vs. separation of intra- and extracellular signal.

J Magn Reson Imaging 2019 Jan 25. Epub 2019 Jan 25.

Computer Assisted Clinical Medicine, Heidelberg University, Mannheim, Germany.

Background: Triple-quantum (TQ) filtered sequences have become more popular in sodium MR due to the increased usage of scanners with field strengths exceeding 3T. Disagreement as to whether TQ signal can provide separation of intra- and extracellular compartments persists.

Purpose: To provide insight into TQ signal behavior on a cellular level. Read More

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http://dx.doi.org/10.1002/jmri.26666DOI Listing
January 2019

Determining the optimal postlabeling delay for arterial spin labeling using subject-specific estimates of blood velocity in the carotid artery.

J Magn Reson Imaging 2019 Jan 25. Epub 2019 Jan 25.

Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.

Background: Arterial spin labeling with 3D acquisition requires determining a single postlabeling delay (PLD) value. PLD affects the signal-to-noise ratio (SNR) per unit time as well as quantitative cerebral blood flow (CBF) values due to its bearing on the presence of a vascular signal.

Purpose: To search for an optimal PLD for pseudocontinuous arterial spin labeling (pCASL) using patient-specific carotid artery blood velocity measurements. Read More

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http://dx.doi.org/10.1002/jmri.26670DOI Listing
January 2019

Fetal brain development at 25-39 weeks gestational age: A preliminary study using intravoxel incoherent motion diffusion-weighted imaging.

J Magn Reson Imaging 2019 Jan 24. Epub 2019 Jan 24.

Department of Radiology & Functional and Molecular Imaging Key Lab of Shaanxi Province, Tangdu Hospital, Fourth Military Medical University (Air Force Medical University), Shaanxi, China.

Background: The fetal brain developmental changes of water diffusivity and perfusion has not been extensively explored.

Purpose/hypothesis: To evaluate the fetal brain developmental changes of water diffusivity and perfusion using intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI).

Study Type: Prospective. Read More

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http://doi.wiley.com/10.1002/jmri.26667
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http://dx.doi.org/10.1002/jmri.26667DOI Listing
January 2019
3 Reads
3.210 Impact Factor

Association of distant recurrence-free survival with algorithmically extracted MRI characteristics in breast cancer.

J Magn Reson Imaging 2019 Jan 22. Epub 2019 Jan 22.

Department of Radiology, Duke University School of Medicine, Durham, North Carolina, USA.

Background: While important in diagnosis of breast cancer, the scientific assessment of the role of imaging in prognosis of outcomes and treatment planning is limited.

Purpose: To evaluate the potential of using quantitative imaging variables for stratifying risk of distant recurrence in breast cancer patients.

Study Type: Retrospective. Read More

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http://dx.doi.org/10.1002/jmri.26648DOI Listing
January 2019

Fast myocardial T mapping using shortened inversion recovery based schemes.

J Magn Reson Imaging 2019 Jan 22. Epub 2019 Jan 22.

School of Biomedical Engineering and Imaging Sciences, Faculty of Life Sciences and Medicine, King's College London, United Kingdom.

Background: Myocardial T mapping shows promise for assessment of cardiomyopathies. Most myocardial T mapping techniques, such as modified Look-Locker inversion recovery (MOLLI), generate one T map per breath-held acquisition (9-17 heartbeats), which prolongs multislice protocols and may be unsuitable for patients with breath-holding difficulties.

Purpose: To develop and characterize novel shortened inversion recovery based T mapping schemes of 2-5 heartbeats. Read More

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http://doi.wiley.com/10.1002/jmri.26649
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http://dx.doi.org/10.1002/jmri.26649DOI Listing
January 2019
4 Reads

Resonate: Reflections and recommendations on implicit biases within the ISMRM.

J Magn Reson Imaging 2019 Jan 21. Epub 2019 Jan 21.

Department of Medical Biophysics, Western University, London, Ontario, Canada.

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http://dx.doi.org/10.1002/jmri.26593DOI Listing
January 2019

T mapping for assessment of renal allograft fibrosis.

J Magn Reson Imaging 2019 Jan 21. Epub 2019 Jan 21.

Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Background: There is an unmet need for noninvasive methods to diagnose and stage renal allograft fibrosis.

Purpose: To investigate the utility of T measured with MRI for the assessment of fibrosis in renal allografts.

Study Type: Institutional Review Board (IRB)-approved prospective. Read More

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http://doi.wiley.com/10.1002/jmri.26656
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http://dx.doi.org/10.1002/jmri.26656DOI Listing
January 2019
6 Reads

Classifying cognitive impairment based on the spatial heterogeneity of cerebral blood flow images.

J Magn Reson Imaging 2019 Jan 21. Epub 2019 Jan 21.

Department of Medical Biophysics, University of Toronto, ON, Canada.

Background: The spatial coefficient of variation (sCoV) of arterial spin-labeled (ASL) MRI can index cerebral blood flow spatial heterogeneity. This metric reflects delayed blood delivery-seen as a hyperintense ASL signal juxtaposed by hypointense regions.

Purpose: To investigate the use of ASL-sCoV in the classification of cognitively unimpaired (CU), mild cognitive impairment (MCI), and Alzheimer's disease (AD) cohorts. Read More

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http://doi.wiley.com/10.1002/jmri.26650
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http://dx.doi.org/10.1002/jmri.26650DOI Listing
January 2019
6 Reads

APT-weighted MRI: Techniques, current neuro applications, and challenging issues.

J Magn Reson Imaging 2019 Jan 20. Epub 2019 Jan 20.

Division of MR Research, Department of Radiology, Johns Hopkins University, Baltimore, Maryland, USA.

Amide proton transfer-weighted (APTw) imaging is a molecular MRI technique that generates image contrast based predominantly on the amide protons in mobile cellular proteins and peptides that are endogenous in tissue. This technique, the most studied type of chemical exchange saturation transfer imaging, has been used successfully for imaging of protein content and pH, the latter being possible due to the strong dependence of the amide proton exchange rate on pH. In this article we briefly review the basic principles and recent technical advances of APTw imaging, which is showing promise clinically, especially for characterizing brain tumors and distinguishing recurrent tumor from treatment effects. Read More

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http://dx.doi.org/10.1002/jmri.26645DOI Listing
January 2019
2 Reads
3.210 Impact Factor

Diagnostic performance of diffusion-weighted (DWI) and dynamic contrast-enhanced (DCE) MRI for the differentiation of benign from malignant soft-tissue tumors.

J Magn Reson Imaging 2019 Jan 20. Epub 2019 Jan 20.

Department of Radiology, Inje University Haeundae Paik Hospital, Busan, Korea.

Background: A wide range of specificity values for the differentiation of benign and malignant soft-tissue tumors show the limitations of conventional MRI features. The data obtained by quantitative analysis of diffusion-weighted image (DWI) and dynamic contrast-enhanced (DCE) MRIs would provide more objective results, especially in terms of cellularity and perfusion.

Purpose: To evaluate the diagnostic efficacies of DWI and DCE MRI for the differentiation of malignant and benign soft-tissue tumors. Read More

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http://doi.wiley.com/10.1002/jmri.26607
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http://dx.doi.org/10.1002/jmri.26607DOI Listing
January 2019
3 Reads

Risk factors of radiotherapy-induced cerebral microbleeds and serial analysis of their size compared with white matter changes: A 7T MRI study in 113 adult patients with brain tumors.

J Magn Reson Imaging 2019 Jan 20. Epub 2019 Jan 20.

Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, USA.

Background: Although radiation therapy (RT) contributes to survival benefit in many brain tumor patients, it has also been associated with long-term brain injury. Cerebral microbleeds (CMBs) represent an important manifestation of radiation-related injury.

Purpose: To characterize the change in size and number of CMBs over time and to evaluate their relationship to white matter structural integrity as measured using diffusion MRI indices. Read More

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http://dx.doi.org/10.1002/jmri.26651DOI Listing
January 2019

Contrast-enhanced MRI for breast cancer screening.

J Magn Reson Imaging 2019 Jan 18. Epub 2019 Jan 18.

Center for Advanced Imaging Innovation and Research / Department of Radiology, Laura and Isaac Perlmutter Cancer Center, New York University School of Medicine, New York, New York, USA.

Multiple studies in the first decade of the 21 century have established contrast-enhanced breast MRI as a screening modality for women with a hereditary or familial increased risk for the development of breast cancer. In recent studies, in women with various risk profiles, the sensitivity ranges between 81% and 100%, which is approximately twice as high as the sensitivity of mammography. The specificity increases in follow-up rounds to around 97%, with positive predictive values for biopsy in the same range as for mammography. Read More

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http://dx.doi.org/10.1002/jmri.26654DOI Listing
January 2019
2 Reads

The need for short MRI examinations: A musculoskeletal perspective.

J Magn Reson Imaging 2019 Jan 18. Epub 2019 Jan 18.

Department of Radiology of Biomedical Imaging, University of California, San Francisco, California, USA.

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http://dx.doi.org/10.1002/jmri.26565DOI Listing
January 2019

Multiparameter diffusion-weighted imaging for characterizing pathological patterns in lupus nephritis patients: A preliminary study.

J Magn Reson Imaging 2019 Jan 18. Epub 2019 Jan 18.

Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Pudong, Shanghai, China.

Background: Microstructural changes of lupus nephritis (LN) kidney such as inflammatory cell infiltration or fibrosis could influence water molecular movement or diffusion, which indicates that diffusion-weighted imaging (DWI) may become a valuable tool in evaluation of this disease.

Purpose: To explore whether multiparameter diffusion-weighted imaging (mDWI) could contribute to characterize pathological patterns in LN patients.

Study Type: Retrospective. Read More

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http://dx.doi.org/10.1002/jmri.26657DOI Listing
January 2019
1 Read

Aortic dilatation associates with flow displacement and increased circumferential wall shear stress in patients without aortic stenosis: A prospective clinical study.

J Magn Reson Imaging 2019 Jan 18. Epub 2019 Jan 18.

Department of Clinical Radiology, Kuopio University Hospital, Imaging Center, Kuopio, Finland.

Background: The relationship between blood flow characteristics and ascending aortic (AA) dilatation has not been studied in patients with a tricuspid aortic valve (TAV) without aortic stenosis.

Purpose: To evaluate whether 4D flow characteristics determined in MRI are related to AA dilatation by comparing dilated AA and nondilated AA subjects with TAV.

Study Type: Prospective. Read More

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http://dx.doi.org/10.1002/jmri.26655DOI Listing
January 2019
1 Read

Integration of Neural Reward Processing and Appetite-Related Signaling in Obese Females: Evidence From Resting-State fMRI.

J Magn Reson Imaging 2019 Jan 17. Epub 2019 Jan 17.

Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

Background: The reward-related regions have been considered a crucial component in the regulation of eating behavior. Furthermore, appetite-related regions associated with reward can influence eating behaviors through altered functional activity related to food in brain areas associated with emotion, memory, sensory processing, motor function, and cognitive control.

Purpose: To investigate the key nodes in obese females of reward-related regions and, based on key nodes, to evaluate the directionality of functional connectivity between key nodes and appetite-related regions. Read More

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http://doi.wiley.com/10.1002/jmri.26576
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http://dx.doi.org/10.1002/jmri.26576DOI Listing
January 2019
4 Reads

3D-ASL perfusion correlates with VEGF expression and overall survival in glioma patients: Comparison of quantitative perfusion and pathology on accurate spatial location-matched basis.

J Magn Reson Imaging 2019 Jan 16. Epub 2019 Jan 16.

Department of Radiology, Affiliated Huashan Hospital of Fudan University, Shanghai, P.R. China.

Background: There is a need for an imaging-based tool for measuring vascular endothelial growth factor (VEGF) expression and overall survival (OS) in patients with glioma.

Purpose: To assess the correlation between cerebral blood flow (CBF), measured by 3D pseudo-continuous arterial spin-labeling (3D-ASL), and VEGF expression in gliomas on the basis of coregistered localized biopsy, and investigate whether CBF correlated with survival month (SM) in glioma patients.

Study Type: Prospective cohort. Read More

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http://doi.wiley.com/10.1002/jmri.26562
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http://dx.doi.org/10.1002/jmri.26562DOI Listing
January 2019
6 Reads

Multisite reliability and repeatability of an advanced brain MRI protocol.

J Magn Reson Imaging 2019 Jan 16. Epub 2019 Jan 16.

Advanced Imaging Research Center, Oregon Health & Science University, Portland, Oregon, USA.

Background: MRI is the imaging modality of choice for diagnosis and intervention assessment in neurological disease. Its full potential has not been realized due in part to challenges in harmonizing advanced techniques across multiple sites.

Purpose: To develop a method for the assessment of reliability and repeatability of advanced multisite-multisession neuroimaging studies and specifically to assess the reliability of an advanced MRI protocol, including multiband fMRI and diffusion tensor MRI, in a multisite setting. Read More

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http://dx.doi.org/10.1002/jmri.26652DOI Listing
January 2019

Intravoxel Incoherent Motion Combined With Dynamic Contrast-Enhanced Perfusion MRI of Early Cervical Carcinoma: Correlations Between Multimodal Parameters and HIF-1α Expression.

J Magn Reson Imaging 2019 Jan 16. Epub 2019 Jan 16.

Department of MR Research, GE Healthcare, Beijing, China.

Background: The identification of hypoxia inducible factor (HIF-1α) expression is helpful for the quantitative assessment of tumor hypoxia. The application of multimodal imaging techniques may play a part in the assessment of HIF-1α expression of cervical carcinoma.

Purpose: To investigate the correlations between multiple imaging parameters and HIF-1α expression of early cervical carcinoma and to determine whether tumor hypoxia can be predicted using multisequence imaging parameters. Read More

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http://doi.wiley.com/10.1002/jmri.26604
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http://dx.doi.org/10.1002/jmri.26604DOI Listing
January 2019
3 Reads

Crossing muscle fibers of the human tongue resolved in vivo using constrained spherical deconvolution.

J Magn Reson Imaging 2019 Jan 16. Epub 2019 Jan 16.

Department of Radiology and Nuclear Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.

Background: Surgical resection of tongue cancer may impair swallowing and speech. Knowledge of tongue muscle architecture affected by the resection could aid in patient counseling. Diffusion tensor imaging (DTI) enables reconstructions of muscle architecture in vivo. Read More

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http://doi.wiley.com/10.1002/jmri.26609
Publisher Site
http://dx.doi.org/10.1002/jmri.26609DOI Listing
January 2019
4 Reads

Diagnostic performance of MR for hepatocellular carcinoma based on LI-RADS v2018, compared with v2017.

J Magn Reson Imaging 2019 Jan 15. Epub 2019 Jan 15.

Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, P.R. China.

Background: The Liver Imaging Reporting and Data System (LI-RADS) is widely adopted for noninvasive diagnosis of hepatocellular carcinoma (HCC). It's updated to version 2018 recently, with some major changes compared with v2017. However, the diagnostic performance of LI-RADS v2018 and its difference with v2017 are yet to be validated. Read More

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http://dx.doi.org/10.1002/jmri.26640DOI Listing
January 2019

Machine learning-based prediction of future breast cancer using algorithmically measured background parenchymal enhancement on high-risk screening MRI.

J Magn Reson Imaging 2019 Jan 16. Epub 2019 Jan 16.

Department of Radiology, Duke University School of Medicine, Durham, North Carolina, USA.

Background: Preliminary work has demonstrated that background parenchymal enhancement (BPE) assessed by radiologists is predictive of future breast cancer in women undergoing high-risk screening MRI. Algorithmically assessed measures of BPE offer a more precise and reproducible means of measuring BPE than human readers and thus might improve the predictive performance of future cancer development.

Purpose: To determine if algorithmically extracted imaging features of BPE on screening breast MRI in high-risk women are associated with subsequent development of cancer. Read More

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http://dx.doi.org/10.1002/jmri.26636DOI Listing
January 2019

Functional parameters impairment after MRI in a patient with a transcatheter pacing system.

J Magn Reson Imaging 2019 Jan 15. Epub 2019 Jan 15.

Department of Electrophysiology, University Heart Centre Cologne University Hospital Cologne Cologne, Germany.

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http://dx.doi.org/10.1002/jmri.26588DOI Listing
January 2019
1 Read

Altered functional connectivity of the marginal division in Parkinson's disease with mild cognitive impairment: A pilot resting-state fMRI study.

J Magn Reson Imaging 2019 Jan 15. Epub 2019 Jan 15.

School of Medicine, Nankai University, Tianjin, P.R. China.

Background: The marginal division (MrD) is an important subcortical center involved in learning and memory. Mild cognitive impairment (MCI) is commonly seen in patients with Parkinson's disease (PD), but the neurobiological basis is yet to be elucidated.

Purpose: To use resting-state functional magnetic resonance imaging (rs-fMRI) to explore the altered functional connectivity (FC) of the MrD in patients with PD-MCI. Read More

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http://dx.doi.org/10.1002/jmri.26548DOI Listing
January 2019
3 Reads

Low-field MRI: An MR physics perspective.

J Magn Reson Imaging 2019 Jan 13. Epub 2019 Jan 13.

C.J.Gorter Center for High Field MRI, Department of Radiology, Leiden University Medical Centre, The Netherlands.

Historically, clinical MRI started with main magnetic field strengths in the ∼0.05-0.35T range. Read More

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http://dx.doi.org/10.1002/jmri.26637DOI Listing
January 2019