1,484 results match your criteria Journal of Lower Genital Tract Disease [Journal]


Descriptors of Vulvodynia: A Multisocietal Definition Consensus (International Society for the Study of Vulvovaginal Disease, the International Society for the Study of Women Sexual Health, and the International Pelvic Pain Society).

J Low Genit Tract Dis 2019 Feb 12. Epub 2019 Feb 12.

Department of Obstetrics and Gynecology, The George Washington University School of Medicine and Health Sciences and the Center for Vulvovaginal Disorders, Washington, DC.

Objectives: Three scientific societies, the International Society for the Study of Vulvovaginal Disease (ISSVD), the International Society for the Study of Women Sexual Health (ISSWSH), and the International Pelvic Pain Society (IPPS) developed the "2015 ISSVD, ISSWSH, and IPPS Consensus Terminology and Classification of Persistent Vulvar Pain and Vulvodynia" (referred to as the "2015 consensus terminology").The terminology included 11 descriptors of vulvodynia. However, the definitions of the descriptors were not included in the 2015 consensus terminology publications. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000461DOI Listing
February 2019

Reimbursement Incentives to Improve Adherence to Follow-Up of Cervical Cancer Cytology Screening Results in Peru.

J Low Genit Tract Dis 2019 Feb 7. Epub 2019 Feb 7.

Augusta University, Augusta, GA.

Objective: The purpose of this study was to determine Peruvian women's attitudes toward novel reimbursement incentives used to improve adherence to obtaining cervical cytology test results.

Materials And Methods: Women presenting for cervical cancer screening in Peru completed a 34-item Investigational Review Board-approved questionnaire. The questionnaire determined their attitudes toward various reimbursement incentives to improve adherence to obtaining cervical cytology results. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000459DOI Listing
February 2019

Vulvovaginal Discomfort Is Common in Both Premenopausal and Postmenopausal Women.

J Low Genit Tract Dis 2019 Feb 7. Epub 2019 Feb 7.

Vincent Center for Reproductive Biology, Massachusetts General Hospital, Boston, MA.

Objectives: We surveyed women from a primary care population to assess the prevalence of unreported vulvovaginal symptoms.

Materials And Methods: A random sample of women aged 18 to 84 years without a diagnosis of vulvovaginitis or vulvodynia in the past year were surveyed anonymously about prevalence and severity of vulvar and vaginal symptoms of itching, burning, irritation, vaginal discharge, vaginal dryness, and vulvovaginal pain in the past month. Women reporting at least 1 moderate-severe symptom were considered symptomatic. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000460DOI Listing
February 2019
2 Reads

Factors Related to Overtreatment in the See-and-Treat Approach: A Retrospective Multicentric Observational Study.

J Low Genit Tract Dis 2019 Jan 30. Epub 2019 Jan 30.

Gynecological Oncology Unit, Centro di Riferimento Oncologico - National Cancer Institute, Aviano, Italy.

Objective: The aim of the study was to evaluate the association between colposcopic features, age, menopausal status, and overtreatment in women subjected to "see-and-treat" approach, to identify subgroups of patients in which this approach could be more appropriate.

Materials And Methods: Retrospective multicentric cohort study conducted on women older than 25 years, with a high-grade squamous cytological report and a visible squamocolumnar junction, in which colposcopy and the excisional procedure were performed at the same time without a previous cervical biopsy (see and treat). Overtreatment was defined as histopathological finding of cervical intraepithelial lesion grade 1 or normal tissue. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000455DOI Listing
January 2019
5 Reads

Observed Colposcopy Practice in US Community-Based Clinics: The Retrospective Control Arm of the IMPROVE-COLPO Study.

J Low Genit Tract Dis 2019 Jan 25. Epub 2019 Jan 25.

Oklahoma Cancer Specialists and Research Institute and University of Oklahoma School of Community Medicine, Tulsa, OH.

Objective: The aim of the study was to characterize colposcopy practice and management of women with cervical abnormalities in US community-based clinics.

Materials And Methods: IMPROVE-COLPO was a 2-arm study of colposcopy patients with an abnormal screening result. The prospective arm recruited women to undergo examination with a commercial digital colposcope. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000454DOI Listing
January 2019
2 Reads

Should We Always Biopsy in Clinically Evident Lichen Sclerosus?

J Low Genit Tract Dis 2019 Jan 25. Epub 2019 Jan 25.

Department of Dermatology, South Infirmary Victoria University Hospital, Cork, Ireland.

The aims of the study were to review cases of clinically diagnosed lichen sclerosus (LS) and to compare the histological features found on biopsy to clinical features seen on examination.

Methods: A retrospective chart review was undertaken of patients attending a specialist vulval service between 2013 and 2015 with a clinical diagnosis of LS. Patients in whom there was clinical diagnostic uncertainty or those with features of lichen planus or lichen planus/LS overlap were excluded. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000457DOI Listing
January 2019

Mindfulness-Based Group Cognitive Behavior Therapy for Provoked Localized Vulvodynia: A Randomized Controlled Trial.

J Low Genit Tract Dis 2019 Jan 25. Epub 2019 Jan 25.

Oregon Health & Science University, Portland, OR.

Objective: The aim of the study was to compare the effectiveness of mindfulness-based group cognitive behavior therapy (M-gCBT) versus education support group therapy for the pain and distress associated with provoked localized vulvodynia.

Materials And Methods: Participants were randomized to M-gCBT or education support group therapy. Mindfulness-based group cognitive behavior participants attended 8 weekly sessions. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000456DOI Listing
January 2019
1 Read

Response to "Immediate Loop Electrode Excisional Procedure for High-Grade Cervical Cytology: One Size Fits All?"

J Low Genit Tract Dis 2019 Jan;23(1):85

Magee Women's Hospital - University of Pittsburgh Medical Center, Pittsburgh, PA Reproductive Biology - Obstetrics and Gynecology UH Cleveland Medical Center Cleveland, OH.

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http://dx.doi.org/10.1097/LGT.0000000000000451DOI Listing
January 2019
1 Read

Calcinosis Cutis of the Vulva: A Review.

J Low Genit Tract Dis 2019 Jan;23(1):75-76

Department of Pathology & Laboratory Medicine, Rutgers-New Jersey Medical School, Newark, NJ.

Idiopathic calcinosis cutis (CC) is an uncommon skin condition. Although it has been reported many times in the scrotum, it is exceedingly rare in the vulva. Most reports of vulvar CC are in children. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000425DOI Listing
January 2019
5 Reads

Should Self-Sampling Be an Option for Women in the United States?

J Low Genit Tract Dis 2019 Jan;23(1):54-57

University of South Alabama, Mitchell Cancer Institute, Mobile, AL.

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http://dx.doi.org/10.1097/LGT.0000000000000453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325773PMC
January 2019
4 Reads

Why Do Women Get Cervical Cancer in an Organized Screening Program in Canada?

J Low Genit Tract Dis 2019 Jan;23(1):1-6

Preventive Care - Cancer Care Ontario.

Objective: The aim of the study was to determine factors associated with the development of cervical malignancy among women participating in an organized cervical screening program.

Materials And Methods: A population-based retrospective cohort study was performed examining the screening histories 2 to 10 years before diagnosis of invasive cancer in Ontario women between 2011 and 2014.

Results: A total of 2,002 cases of cervical cancer were identified; 1,358 (68%) were squamous cell carcinomas and 644 (32%) were adenocarcinomas. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000450DOI Listing
January 2019
10 Reads
1.110 Impact Factor

Anti-Inflammatory Effect of Surfactant Lipid in the Vaginal Mucosa: A Pilot Study.

J Low Genit Tract Dis 2019 Jan;23(1):71-74

Department of Obstetrics & Gynecology, Pennsylvania State University College of Medicine, Hershey, PA.

Objective: The aim of the study was to test the hypothesis that vaginal administration of surfactant lipids, which may counter-balance the proinflammatory effects of vaginal surfactant protein A, will decrease proinflammatory cytokines and increase anti-inflammatory cytokines in vaginal mucosal fluid in healthy women.

Materials And Methods: Three groups of healthy cycling women were randomized to receive vaginally a single dose of the following: (1) low-dose calfactant, a type of surfactant lipids, 0.8 mg/ml; (2) high-dose calfactant 8. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000448DOI Listing
January 2019
1 Read

Immediate Loop Electrode Excisional Procedure for High-Grade Cervical Cytology: One Size Fits All?

J Low Genit Tract Dis 2019 Jan;23(1):84

Hospital Lusíadas Porto Porto, Portugal, Unidade de Tracto Genital Inferior, Centro Hospitalar de São João, Porto, Portugal Serviço de Ginecologia e Obstetrícia, Centro Hospitalar de São João, Porto, Portugal Unidade de Tracto Genital Inferior, Centro Hospitalar de São João, Porto, Portugal.

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http://dx.doi.org/10.1097/LGT.0000000000000452DOI Listing
January 2019
7 Reads

Importance of Colposcopy Impression in the Early Diagnosis of Posthysterectomy Vaginal Cancer.

J Low Genit Tract Dis 2019 Jan;23(1):13-17

Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.

Objective: The aim of the study was to investigate the value of cytology, high-risk human papillomavirus (hrHPV) status and colposcopy in the early diagnosis of vaginal cancer after hysterectomy.

Materials And Methods: A retrospective study was performed in the Obstetrics and Gynecology Hospital of Fudan University. Posthysterectomy patients who were diagnosed with vaginal high-grade intraepithelial lesion (HSIL) by colposcopy-directed biopsy with colposcopy impression of extensive HSIL or suspicion of cancer and underwent upper or total vaginectomy from January 2009 to December 2017 were included. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000446DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325769PMC
January 2019
16 Reads

Localized Provoked Vulvodynia: Association With Nerve Growth Factor and Transient Receptor Potential Vanilloid Type 1 Genes Polymorphisms.

J Low Genit Tract Dis 2019 Jan;23(1):58-64

Department of Obstetrics & Gynecology, Galilee Medical Center, Nahariya, Israel.

Objective: The aim of the study was to study the associations between localized provoked vulvodynia (LPV) and several single-nucleotide polymorphisms (SNPs) in the transient receptor potential vanilloid type 1 (TRPV1), nerve growth factor (NGF), and the heparanase (HPSE) genes.

Materials And Methods: Prevalence of SNPs among 65 women with moderate or severe primary LPV (initial symptoms occur with first provoking physical contact) and 126 healthy, ethnically matched controls was analyzed in an observational case-control study. Each participant answered a questionnaire addressing familial LPV occurrence and comorbid pain conditions. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000445DOI Listing
January 2019
9 Reads

Improved anal Cytology Sampling: Tush Brush Compared With Dacron Swab.

J Low Genit Tract Dis 2019 Jan;23(1):48-53

Georgia Cancer Center, Augusta University, Augusta, GA.

Objective: The objective of this study was to determine the performance characteristics of the Tush brush (TB) compared with a saline moistened Dacron swab (DS) as anal cytology sampling devices.

Materials And Methods: TB and DS anal cytology tests were randomly collected from 146 patients presenting for anal cytology. High-resolution anoscopy and biopsies were obtained as indicated. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000447DOI Listing
January 2019
2 Reads

Trainee Performance in Loop Electrosurgical Excision Procedure (LEEP) After Simulation Training.

J Low Genit Tract Dis 2019 Jan;23(1):28-32

University of Queensland Faculty of Medicine, Brisbane, Queensland, Australia.

Objective: The aim of the study was to review the performance of trainees in loop electrosurgical excision procedure (LEEP) procedures after the introduction of a simulation training program.

Materials And Method: A simulation training program was introduced in September 2016 for gynecology trainees at the study institution. Trainees were encouraged to perform at least 3 simulated LEEP procedures before operating. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000443DOI Listing
January 2019

Onclarity Human Papillomavirus Extended Genotyping in the Management of Cervical Intraepithelial Neoplasia 2+ Lesions.

J Low Genit Tract Dis 2019 Jan;23(1):39-42

Clinical Analysis Laboratory, Humanitas Research Hospital, Rozzano, Milan, Italy.

Objective: Many methods are available today for human papillomavirus (HPV) testing; they differ for technology, targets, and information on the genotypes detected. In this study, we evaluated the performance of the Onclarity HPV assay in detection and follow-up of cervical preneoplastic lesions.

Materials And Methods: One hundred sixty-seven women referred to the European Institute of Oncology, Milan, for treatment of cervical lesions were enrolled. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000441DOI Listing
January 2019
3 Reads

Risk Factor Analysis of Persistent High-Grade Squamous Intraepithelial Lesion After Loop Electrosurgical Excision Procedure Conization.

J Low Genit Tract Dis 2019 Jan;23(1):24-27

Medical Center of Diagnosis and Treatment for Cervical Diseases, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China.

Objective: The aim of the study was to analyze the clinical outcomes of high-grade squamous intraepithelial lesion (HSIL) 6 months after loop electrosurgical excision procedure (LEEP). We explored the risk factors of persistent cervical HSIL after LEEP and evaluated the methods of follow-up.

Patients And Methods: This retrospective study included women who underwent a LEEP and had a diagnosis of HSIL in their LEEP specimen during 2011 to 2015. Read More

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http://Insights.ovid.com/crossref?an=00128360-900000000-9945
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http://dx.doi.org/10.1097/LGT.0000000000000444DOI Listing
January 2019
3 Reads

Vulvar Edema as Presenting Complication of Simultaneous Pancreas-Kidney Transplantation With Bladder Drainage.

J Low Genit Tract Dis 2019 Jan;23(1):82-83

The Ohio State University Wexner Medical Center, Columbus, OH.

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http://dx.doi.org/10.1097/LGT.0000000000000442DOI Listing
January 2019
2 Reads

Comparison of Electrosurgical Devices for Cervical Conization: Novel Monopolar Scalpel (VIO) Versus Ultrasonic Scalpel.

J Low Genit Tract Dis 2019 Jan;23(1):43-47

Gynecology Service, National Kyushu Cancer Center, Fukuoka, Japan.

Objective: The aim of this study was to compare the outcomes associated with the use of a novel monopolar scalpel with those associated with the use of an ultrasonic scalpel for cervical conization of cervical intraepithelial neoplasia.

Materials And Methods: We conducted a retrospective cross-sectional study in patients treated in our institute between April 2010 and March 2017. We used either the VIO monopolar scalpel (VIO) or Harmonic ultrasonic scalpel (HS) for cervical conization. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000439DOI Listing
January 2019
13 Reads

Gynecologic Screening for Men in an OBGYN Resident Community Outreach Clinic: The Transgender Care Experience.

J Low Genit Tract Dis 2018 Oct;22(4):333-335

Department of ObGyn, The Reading Hospital of Tower Health, Reading, PA.

Objective: The aim of the study was to promote the importance of providing gynecologic screening for transgender men (TGM) who desire to keep their female organs.

Materials And Methods: In June 2015, the Women's Health Center (WHC) at Reading Hospital was approached to become a resource for transgender (TG) patients in our community. This also presented the opportunity to develop an educational program for OBGYN residents/providers in TG healthcare. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000429DOI Listing
October 2018
1 Read

Human Papillomavirus Knowledge, Attitudes, Practices, and Prevalence Among Men Who Have Sex With Men in Monrovia, Liberia.

J Low Genit Tract Dis 2018 Oct;22(4):326-332

Icahn School of Medicine at Mount Sinai, New York City, NY.

Objective: The aim of this study was to assess human papillomavirus (HPV) prevalence, knowledge, attitudes, and practices, among men who have sex with men (MSM) in Monrovia, Liberia.

Materials And Method: This cross-sectional study was conducted with 107 MSM, aged 18 to 58 years, completing questionnaires and anal HPV screenings. Using peer-educators and direct community involvement, demographics, risk factors, and HPV knowledge data were collected. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000436DOI Listing
October 2018

Cervical Cancer Incidence Among Elderly Women in Massachusetts Compared With Younger Women.

J Low Genit Tract Dis 2018 Oct;22(4):314-317

Department of Obstetrics and Gynecology, Boston Medical Center, Boston University School of Medicine, Boston, MA.

Importance: Current cancer screening guidelines recommend cessation of cervical cancer screening at the age of 65 years for most women. To examine residual risk among elderly women, we compared cervical cancer incidence rates (IRs) in Massachusetts from 2004 to 2015 among women younger than 65 years versus 65 years and older.

Materials And Methods: The Massachusetts Cancer Registry was used to identify all women diagnosed with cervical cancer between January 01, 2004, to December 31, 2015. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161498PMC
October 2018
17 Reads
1.110 Impact Factor

Cervical Cancer Screening Beliefs and Prevalence of LSIL/HSIL Among a University-Based Population in Cameroon.

J Low Genit Tract Dis 2018 Oct;22(4):274-279

Maricopa Integrated Health System, Phoenix, AZ.

Objective: The aim of the study was to determine beliefs and utilization of cervical cancer screening and prevalence of low-grade squamous intraepithelial lesion/high-grade squamous intraepithelial lesion among a university-based population in the Southwest region of Cameroon.

Materials And Methods: A public-private partnership was established between the University of Arizona, University of Buea, and the Cameroon Baptist Convention Health Services. A single-day screening clinic using visual inspection with acetic acid and Lugol's iodine solution (VILI) was provided at the University of Buea. Read More

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http://Insights.ovid.com/crossref?an=00128360-201810000-0000
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http://dx.doi.org/10.1097/LGT.0000000000000433DOI Listing
October 2018
2 Reads

Fact or Fiction? Adipose-Derived Stem Cells and Platelet-Rich Plasma for the Treatment of Vulvar Lichen Sclerosus.

J Low Genit Tract Dis 2019 Jan;23(1):65-70

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of British Columbia.

Objective: The aim of the study was to summarize and review the evidence for the efficacy and safety of adipose-derived stem cells (ADSCs) and platelet-rich plasma (PRP) for the treatment of vulvar lichen sclerosus (LS).

Materials And Methods: PubMed/MEDLINE, Ovid, Web of Science, and clinicaltrials.gov were searched from inception up to May 7, 2018. Read More

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http://Insights.ovid.com/crossref?an=00128360-900000000-9945
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http://dx.doi.org/10.1097/LGT.0000000000000440DOI Listing
January 2019
13 Reads

Expression of Psoriasin in Human Papillomavirus-Induced Cervical High-Grade Squamous Intraepithelial Lesions.

J Low Genit Tract Dis 2019 Jan;23(1):33-38

Department of Clinical Sciences, Division of Obstetrics and Gynecology, Karolinska Institutet Danderyd Hospital, Stockholm, Sweden.

Objectives: Persistent infection with human papillomavirus causes cervical high-grade squamous intraepithelial lesions (HSILs). The role of antimicrobial peptides (AMPs) in premalignant and malignant transformation is not fully understood. In this study, we examined the expression of human β-defensin 1 (HBD-1), HBD-2, HBD-3, LL37, psoriasin, and interleukin 8 (IL-8) in women with HSIL before and 6 months after surgery. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000438DOI Listing
January 2019

Preference for Human Papillomavirus Self-Collection and Papanicolaou: Survey of Underscreened Women in North Carolina.

J Low Genit Tract Dis 2018 Oct;22(4):302-310

Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC.

Objectives: Self-collection of samples for human papillomavirus (HPV) testing (self-collection) has the potential to increase cervical cancer screening among underscreened women. We assessed attitudes toward at-home HPV self-collection compared with clinic-based Pap testing in this higher-risk population.

Materials And Methods: Participants were low-income women in North Carolina overdue for cervical cancer screening. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174678PMC
October 2018
2 Reads

Prevalence of Anal Squamous Intraepithelial Lesions in HIV-1-Infected Young Men Who Have Sex With Men and Transwomen.

J Low Genit Tract Dis 2018 Oct;22(4):340-347

Department of Pediatrics, Division of Pediatric Infectious Diseases, Emory University School of Medicine, Atlanta, GA.

Objective: Anal cancer rates are increasing among HIV-infected persons. Although an efficacious human papillomavirus (HPV) vaccine is available, HPV vaccination rates remain low. Therefore, providers perform anal cancer screening, but there is no consensus on the optimal methods or timing of screening. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158076PMC
October 2018
21 Reads

Cervical Cancer Screening for Women With Disabilities: Time for a New Approach?

J Low Genit Tract Dis 2018 Oct;22(4):318-319

Johns Hopkins University School of Medicine, Baltimore, MD, and.

Women with disabilities are underscreened for cervical cancer compared with the general population, likely because, in part, of both emotional and physical challenges associated with Pap testing. Women with certain disabilities often require an examination under anesthesia to undergo a speculum examination. However, anesthesia is not without risks and the perioperative experience can be burdensome to patients and caregivers. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000432DOI Listing
October 2018
12 Reads

Vaginal Intraepithelial Neoplasia: Clinical Presentation, Management, and Outcomes in Relation to HIV Infection Status.

J Low Genit Tract Dis 2019 Jan;23(1):7-12

Department of Gynecologic Oncology, Hospital Vall d'Hebron, Universitat Autónoma de Barcelona, Barcelona, Spain, and.

Objectives: The data available on vaginal intraepithelial neoplasia (VAIN) and infection by HIV are scarce. We therefore aimed to review the clinical presentation, management, and survival outcomes of VAIN in this group of women.

Materials And Methods: This is an observational cohort study of women diagnosed with VAIN for a 23-year period. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000431DOI Listing
January 2019
3 Reads

Effect of Educational Intervention on Self-Sampling Acceptability and Follow-Up Paps in Border Dwelling Hispanic Females.

J Low Genit Tract Dis 2018 Oct;22(4):295-301

Department of Family and Community, Medicine, Texas Tech University Health Sciences Center El Paso, El Paso, TX.

Objective: The aims of the study were to evaluate the effect of a community outreach worker (promotora)-led high-intensity educational intervention compared with control without promotora-led intervention on cervical cancer screening preference (Pap smear vs self-sampling) and to determine the effect of this preference on subsequent screening completion.

Materials And Methods: This randomized controlled trial compared the effect of educational intervention on women's preferences for self-sampling for human papillomavirus. Inclusion criteria were women aged 30 to 65 years and no cervical cancer screening in 3 years or more. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000424DOI Listing
October 2018

5-Flouorouracil Is an Attractive Medical Treatment in Women With Vaginal Intraepithelial Neoplasia: A Meta-Analysis.

J Low Genit Tract Dis 2018 Oct;22(4):375-381

Department of Gynaecological Oncology, St James's University Hospital, Leeds Teaching Hospitals NHS, Leeds, United Kingdom.

Objective: In the absence of standard guidelines, the management of vaginal intraepithelial neoplasia (VaIN) remains a field of debate. The aim of this systematic review and meta-analysis was to ascertain the 5-flouorouracil (5-FU) effectiveness in this context.

Materials And Methods: A literature search was conducted throughout the PubMed, EMBASE, SCOPUS, ClinicalTrials. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000415DOI Listing
October 2018
1 Read

Cervical Adenoid Basal Carcinoma: Clinicopathologic Features of 9 Cases With Reference to CK17 and Ki-67 Expression.

J Low Genit Tract Dis 2019 Jan;23(1):77-81

Department of Surgical Pathology, the Affiliated Women's Hospital, School of Medicine, Zhejiang University. Zhejiang Province, China.

Objective: The aims of this study were to clarify the histological features of adenoid basal carcinoma (ABC) and determine whether cytokeratin 17 (CK17) and Ki-67 can facilitate the differential diagnosis of ABC from squamous cell carcinoma (SCC).

Materials And Methods: Nine cases of pure ABC were collected from the files of the Division of Pathology at the Zhejiang University Hospital Women's School of Medicine. For comparison, 20 cases of moderately to poorly differentiated cervical SCC, including 2 of basaloid SCC, were also retrieved from the same period. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000428DOI Listing
January 2019

Effect of Immediate Loop Electrode Excisional Procedure for High-Grade Cervical Cytology in an Urban Academic Clinic Setting.

J Low Genit Tract Dis 2018 Oct;22(4):311-313

Department of Reproductive Biology, MacDonald Women's Hospital, University Hospitals Cleveland Medical Center, Cleveland, OH.

Objective: The aim of the study was to determine whether treating all patients older than 25 years with high-grade squamous intraepithelial lesion (HSIL) Paps with immediate loop electrode excisional procedure (LEEP) improves rates of receiving indicated treatment and evaluating whether this practice results in overtreatment (defined by excisional pathology less than cervical intraepithelial neoplasia 2).

Materials And Methods: This was a retrospective cohort study at an urban, Medicaid-based clinic, which evaluated women older than 25 years with HSIL Pap results seen from June 2011 to December 2016. In June 2013, the clinic practice was restructured and management of HSIL Pap results in patients older than 25 years was standardized to immediate LEEP procedure, without intermediate colposcopic examination. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000426DOI Listing
October 2018

Preventing Global Human Papillomavirus-Associated Lower Genital Disease.

J Low Genit Tract Dis 2018 Oct;22(4):267-268

Gynecology and Obstetrics Emory University School of Medicine Atlanta, GA Division of Cancer Prevention and Control Centers for Disease Control and Prevention Atlanta, GA.

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http://dx.doi.org/10.1097/LGT.0000000000000427DOI Listing
October 2018
1 Read

Risk Factors of Post-Large Loop Excision of the Transformation Zone Recurrent High-Grade Cervical Intraepithelial Lesion: A Prospective Cohort Study.

J Low Genit Tract Dis 2019 Jan;23(1):18-23

Department of Obstetrics and Gynaecology, Hôpital Nord, APHM, Aix-Marseille University (AMU), Univ Avignon, CNRS, IRD, IMBE UMR, Marseille, France.

Objective: The aim of the study was to identify the risk factors of post-large loop excision of the transformation zone (LLETZ) recurrent disease and the impact of colposcopic guidance at the time of LLETZ on that risk.

Materials And Methods: From December 2013 to July 2014, 204 patients who had undergone LLETZ for the treatment of high-grade intraepithelial lesion with fully visible cervical squamocolumnar junction were included. The use of colposcopy during each procedure was systematically documented. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000423DOI Listing
January 2019
19 Reads

To Shave or Not to Shave? A Series of Periclitoral Masses Associated With Depilatory Techniques and a Review of the Literature.

J Low Genit Tract Dis 2018 Oct;22(4):412-414

Department of Obstetrics and Gynecology, Program in Vulvar Health, Oregon Health & Science University, Portland, OR.

Periclitoral masses are uncommon disorders in gynecology often leading to pain and distress. With the popularity of female genital hair grooming and depilation, the vulva has been exposed to new insults including contact dermatitis and folliculitis. The unique anatomy of the protective covering of the clitoral hood may subject hair fragments to trapping, inflammation, irritation, and in some cases abscess formation. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000420DOI Listing
October 2018
1 Read

The Variable Characteristics of Human Papillomavirus in Squamous Cell Carcinoma and Adenocarcinoma of Cervix in China.

J Low Genit Tract Dis 2018 Oct;22(4):355-361

National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Objective: A hospital-based multicenter, retrospective study was conducted to compare the distribution of human papillomavirus (HPV) in squamous cell carcinoma (SCC) and cervical adenocarcinoma (CADC) in China.

Methods: Paraffin-embedded tissue blocks diagnosed as SCC and CADC across China were collected, as well as the total number of diagnosed invasive cervical cancer of the 9 selected centers. DNA enzyme immunoassay, reverse hybridization, and multiplex type-specific polymerase chain reaction were used for HPV genotyping. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000408DOI Listing
October 2018
5 Reads

Cervical Cancer Screening Among Women by Birthplace and Percent of Lifetime Living in the United States.

J Low Genit Tract Dis 2018 Oct;22(4):280-287

Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Atlanta, GA.

Objective: The aim of the study was to provide national estimates of Pap test receipt, by birthplace, and percent of lifetime in the United States (US).

Materials And Methods: Pooled nationally representative data (2005, 2008, 2013, 2015) from the National Health Interview Survey were used to examine differences in Pap test receipt among adult US women by birthplace and percent of lifetime in the US. Descriptive estimates were age-adjusted. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000422DOI Listing
October 2018

The Impact of Racial, Geographic, and Socioeconomic Risk Factors on the Development of Advanced-Stage Cervical Cancer.

J Low Genit Tract Dis 2018 Oct;22(4):269-273

Division of Gynecologic Oncology, University of Alabama at Birmingham, Birmingham, AL.

Objectives: Despite screening, disparities exist in cervical cancer incidence and outcomes. Demographic factors are associated with diagnosis at advanced stage (AS), but less is known about geographic factors. We sought to investigate risk factors for developing AS cervical cancer in Alabama. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158085PMC
October 2018
3 Reads

Outcome Measurement Instruments for Provoked Vulvodynia: A Systematic Review.

J Low Genit Tract Dis 2018 Oct;22(4):396-404

Dermatology Department, The Royal Women's Hospital, Parkville, Victoria, Australia.

Objective: The objective of this study was to detail the outcome measurement instruments used in randomized control trials and observational studies investigating therapeutic interventions for provoked vulvodynia.

Materials And Methods: We searched Ovid Medline, Embase, Emcare, and PyschINFO libraries from database inception through April 2017. We included randomized control trials and observational studies of provoked vulvodynia that used instruments to measure the outcome of therapeutic interventions. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000418DOI Listing
October 2018
11 Reads

Recalcitrant Vulval and Perineal Crohn Disease Responding to Hyperbaric Oxygen Therapy.

J Low Genit Tract Dis 2018 Oct;22(4):409-411

Departments of Dermatology, The Royal Liverpool and Broadgreen University Hospitals, Liverpool, UK.

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http://dx.doi.org/10.1097/LGT.0000000000000417DOI Listing
October 2018

Classic and Hypertrophic Vulvar Lichen Planus.

J Low Genit Tract Dis 2018 Oct;22(4):387-395

Faculty of Health and Medicine, University of Newcastle, Callaghan, New South Wales, Australia.

Objectives: Three types of lichen planus (LP) occur on the vulva: erosive, classic, and hypertrophic. The latter 2 occur on keratinized skin and little is known about their clinicopathologic appearance.

Materials And Methods: Vulvar biopsies of keratinized skin reported as LP or "lichenoid" between 2011 and 2017 were reviewed. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296835PMC
October 2018
14 Reads

International Society for the Study of Vulvovaginal Disease Recommendations Regarding Female Cosmetic Genital Surgery.

J Low Genit Tract Dis 2018 Oct;22(4):415-434

Department of Gynecologic Oncology, Holycross Cancer Center, Kielce, Poland.

Female genital cosmetic surgeries (FGCSs) and procedures are increasingly being advertised as common, simple, and complication-free, capable of not only improving aesthetic appearance but also increasing self-esteem and sexual pleasure.Guidelines for physicians and clear, scientifically correct information for patients must be made available, to minimize the number of ineffective or deleterious procedures.The International Society for the Study of Vulvovaginal Disease positions/recommendations regarding FGCS are as follows:1. Read More

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http://Insights.ovid.com/crossref?an=00128360-201810000-0002
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http://dx.doi.org/10.1097/LGT.0000000000000412DOI Listing
October 2018
12 Reads

Cervical Cytology and Histology After Solid Organ Transplant: A Longitudinal Cohort Study.

J Low Genit Tract Dis 2018 Oct;22(4):362-366

Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN.

Objectives: The ideal frequency of cervical cancer screening in women with solid organ transplants (SOTs) remains to be determined. We aimed to assess the longitudinal rates of cytologic and histologic cervical abnormalities in women after SOT.

Methods: We retrospectively reviewed health records of women aged 18 to 60 years who received their first kidney, liver, pancreas, or combination transplant at Mayo Clinic (Rochester, Minnesota) from 1995 through 2011. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000414DOI Listing
October 2018
3 Reads

Long-Term Outcomes of Women With Recurrent Vulvovaginal Candidiasis After a Course of Maintenance Antifungal Therapy.

J Low Genit Tract Dis 2018 Oct;22(4):382-386

Drexel University College of Medicine and Department of Obstetrics and Gynecology, Philadelphia, PA.

Objectives: Data about long-term clinical outcome after a course of maintenance fluconazole in those with recurrent vulvovaginal candidiasis (RVVC) is lacking. We aimed to determine the rate of recurrence at a minimum of 6 months after completion of maintenance therapy.

Methods: A retrospective analysis of women with Candida albicans RVVC from January 2008 to January 2017 was performed using chart review to obtain information about recurrence after maintenance therapy. Read More

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http://Insights.ovid.com/crossref?an=00128360-201810000-0002
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http://dx.doi.org/10.1097/LGT.0000000000000413DOI Listing
October 2018
9 Reads

Human Papillomavirus Correlates With Histologic Anal High-Grade Squamous Intraepithelial Lesions in Hispanics With HIV.

J Low Genit Tract Dis 2018 Oct;22(4):320-325

Department of Biostatistics and Epidemiology, Graduate School of Public Health, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico.

Objective: To estimate the magnitude of association between anal infection with high-risk human papilloma virus (HR-HPV) types and severity of biopsy-confirmed histopathological anal squamous intraepithelial lesions (SILs) among a clinic-based sample of HIV-infected adults in Puerto Rico.

Methods: This cross-sectional study analyzed data from medical records of adult patients who visited a specialized anal neoplasia clinic from June 2015 to December 2017 (n = 239); sociodemographics, behavioral risk factors, medical history, clinical data, and pathology reports were collected. The magnitude of association between anal HR-HPV and severity of anal SIL, adjusted for potential confounders, was assessed using a multinomial logistic model. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000416DOI Listing
October 2018
4 Reads