1,806 results match your criteria Journal of Investigative Surgery [Journal]


Modified Extraperitoneal Uterosacral Ligament Suspension in Preventing Cuff Prolapse Risk after Vaginal Hysterectomy; 4 Clamp Method.

J Invest Surg 2019 Apr 15:1-7. Epub 2019 Apr 15.

a Department of Obstetrics and Gynecology, Kanuni Sultan Süleyman Research and Training Hospital , Istanbul Health Sciences University , İstanbul, Turkey.

Objectives: The extraperitoneal uterosacral ligament suspension (ULS) can be performed during the removal of the uterus in vaginal hysterectomy to prevent cuff prolapse. In this study, we evaluated the modified extraperitoneal ULS technique in terms of preventing cuff prolapse. Methods/Technique: Forty patients with second and third-stage uterine prolapse who were operated were included in the study. Read More

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http://dx.doi.org/10.1080/08941939.2019.1601305DOI Listing
April 2019
1 Read

The Effect of Pre-emptive Dexketoprofen Administration on Postoperative Pain Management in Patients with Ultrasound Guided Interscalene Block in Arthroscopic Shoulder Surgery.

J Invest Surg 2019 Apr 9:1-7. Epub 2019 Apr 9.

a Department of Anesthesiology and Reanimation , Ataturk University School of Medicine , Erzurum , Turkey.

Background: Postoperative pain is an important problem for patients undergoing shoulder surgery. Our study investigated analgesic efficacy, duration of analgesia, postoperative analgesic use and patient satisfaction with the use of preemptive intravenous dexketoprofen for interscalene block in addition to general anesthesia in arthroscopic shoulder surgery.

Methods: 60 patients, scheduled for arthroscopic shoulder surgery were randomized (30 patients each) into either: - control group (Group1) or dexketoprofen group (Group 2). Read More

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http://dx.doi.org/10.1080/08941939.2019.1576809DOI Listing

Outcomes at 2-Years Follow-Up After Hip Arthroscopy Combining Bone Marrow Concentrate.

J Invest Surg 2019 Apr 7:1-9. Epub 2019 Apr 7.

a Department of Orthopaedic Surgery , Hospital Quirónsalud , Barcelona , Spain.

Introduction: The cartilage injuries are related to femoroacetabular impingement (FAI). The prognostic of the injury depends on the grade of itself. Using bone marrow concentrate (BMC), which contains stem cells, is related to the improvement in diverse tissues. Read More

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https://www.tandfonline.com/doi/full/10.1080/08941939.2018.1
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http://dx.doi.org/10.1080/08941939.2018.1535010DOI Listing
April 2019
2 Reads

Short-Term Outcomes of Three-Port Laparoscopic Right Hemicolectomy Versus Five-Port Laparoscopic Right Hemicolectomy: With a Propensity Score Matching Analysis.

J Invest Surg 2019 Apr 4:1-6. Epub 2019 Apr 4.

a Department of General Surgery, Ruijin Hospital , Shanghai Jiao Tong University School of Medicine , Shanghai , China.

Purpose: The aim of this study is to compare the short-term and pathological outcomes of TPLRC (Three-port laparoscopic right hemicolectomy) and FPLRC (Five-port laparoscopic right hemicolectomy), using propensity score matching analysis.

Methods: One hundred and sixty-eight patients who accepted laparoscopic right hemicolectomy with either three ports or five ports from January 2013 to October 2017 were non-randomly selected and analyzed retrospectively. Propensity score matching model was used to eliminate the patients' selection bias between two groups. Read More

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https://www.tandfonline.com/doi/full/10.1080/08941939.2019.1
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http://dx.doi.org/10.1080/08941939.2019.1579276DOI Listing
April 2019
2 Reads

Influence of Surgical Procedures on Serum Paraoxonase-1-Related Variables and Markers of Inflammation in Hospitalized Patients.

J Invest Surg 2019 Apr 4:1-9. Epub 2019 Apr 4.

a Hospital Universitari de Sant Joan , Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili , Reus , Spain.

Purpose: Surgical stress is a phenomenon not completely understood from the biochemical point of view, although it produces alterations in the oxidative balance and inflammatory status. The present study aimed to investigate the alterations of the circulating levels of paraoxonase-1 (PON1)-related variables and markers of inflammation in hospitalized patients who underwent surgery.

Methods: We recruited 285 hospitalized patients. Read More

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http://dx.doi.org/10.1080/08941939.2019.1597223DOI Listing

Rapamycin Inhibits Nf-ΚB Activation by Autophagy to Reduce Catabolism in Human Chondrocytes.

J Invest Surg 2019 Apr 4:1-13. Epub 2019 Apr 4.

b Department of Orthopedic Surgery , General Hospital of Ningxia Medical University, Ningxia Medical University , Yinchuan , Ningxia , China.

Background And Aim: Osteoarthritis is a disease that is accompanied by inflammation and catabolic disorders in the cartilage. Rapamycin is a good autophagy activator and has an inhibitory effect on inflammation, and autophagy can remove waste generated by catabolic disorders and delay the destruction of cartilage by inflammation. This study was designed to evaluate the effect of rapamycin upon the catabolism in human chondrocytes and unravel underlying mechanism. Read More

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https://www.tandfonline.com/doi/full/10.1080/08941939.2019.1
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http://dx.doi.org/10.1080/08941939.2019.1574321DOI Listing
April 2019
5 Reads

Position of Coracoid Button Predicts Loss of Reduction in Acromioclavicular Joint Dislocation Patients Treated With the Suture-Button.

J Invest Surg 2019 Mar 28:1-6. Epub 2019 Mar 28.

a Department of Orthopaedic Surgery , the Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, and Zhejiang Provincial Key Laboratory of Orthopaedics , Wenzhou , Zhejiang , China.

Background: Loss of reduction is the most common complication after acromioclavicular (AC) joint dislocation treated with the suture-button. Some predictors of it are known, but finding new predictors is an ongoing process. In this study, we evaluate the importance of the position of the coracoid button. Read More

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http://dx.doi.org/10.1080/08941939.2019.1593557DOI Listing
March 2019
2 Reads

The Application of T.SPOT-TB Assay for Early Diagnosis of Active Tuberculosis in Chronic Kidney Disease Patients Receiving Immunosuppressive Treatment.

J Invest Surg 2019 Mar 27:1-6. Epub 2019 Mar 27.

a Department of Nephrology , Beijing Hospital, National Center of Gerontology , Beijing , China.

Background: The current study investigated the clinical application of the T-SPOT.TB assay for detecting tuberculosis (TB) infection in chronic kidney disease patients treated with immunosuppressive therapy.

Methods: Clinical data from 91 patients were retrospectively analyzed. Read More

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https://www.tandfonline.com/doi/full/10.1080/08941939.2019.1
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http://dx.doi.org/10.1080/08941939.2019.1566417DOI Listing
March 2019
4 Reads

Acupoint Massage Can Effectively Promote the Recovery of Gastrointestinal Function after Gynecologic Laparoscopy.

J Invest Surg 2019 Mar 27:1-5. Epub 2019 Mar 27.

a Massage Department , Traditional Chinese Medicine Hospital of Xinjiang Uyghur Autonomous Region , Urumqi , China.

Objective: To investigate the effect of acupoint massage on the recovery of gastrointestinal function in patients after laparoscopic surgery for gynecologic indications.

Methods: A total of 160 patients, who underwent gynecologic laparoscopy from December 2015 to January 2017, were recruited. Half of the patients received standard postoperative nursing (i. Read More

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http://dx.doi.org/10.1080/08941939.2019.1577515DOI Listing
March 2019
1 Read

Dexmedetomidine Ameliorates Post-CPB Lung Injury in Rats by Activating the PI3K/Akt Pathway.

J Invest Surg 2019 Mar 26:1-8. Epub 2019 Mar 26.

a Department of Anesthesiology , Affiliated Hospital of Zunyi Medical University , Zunyi , China.

Purpose: To investigate the protective effects of dexmedetomidine (Dex) on post cardiopulmonary bypass (CPB) lung injury in rats and to explore the possibility of underlying mechanisms involving phosphatidylinositol 3-kinase (PI3K)/Akt.

Materials And Methods: Forty healthy male Sprague-Dawley rats were randomly divided into five groups (n = 8 for each). A left lung ischemia-reperfusion injury model of CPB was established in all five groups. Read More

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http://dx.doi.org/10.1080/08941939.2018.1529839DOI Listing

Acute Aortic Dissection in Young Adult Patients: Clinical Characteristics, Management, and Perioperative Outcomes.

J Invest Surg 2019 Mar 25:1-7. Epub 2019 Mar 25.

f Department of Cardiovascular Surgery , Beijing Anzhen Hospital of Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, and Beijing Engineering Research Center of Vascular Prostheses , Beijing , China.

Background: Acute aorta dissection (AD) is a fatal emergency, however, studies addressing the clinical characteristics, management, and outcome of acute AD in young adult patients aged under 45 years in China are very few.

Methods: A retrospective study including 490 patients with acute AD as the final diagnosis was conducted. Patients' demographics, clinical characteristics, medical history, and laboratory and diagnostic imaging findings were retrieved from medical records. Read More

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http://dx.doi.org/10.1080/08941939.2018.1489916DOI Listing
March 2019
1 Read

The Benefits of Preserving the Coracoid Process and Its Attachments.

Authors:
Zhengan Hao

J Invest Surg 2019 Mar 25:1-2. Epub 2019 Mar 25.

a Department of Orthopaedics , Yuhang Branch of the Second Affilited Hospital of Zhejiang University , Hangzhou , China.

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http://dx.doi.org/10.1080/08941939.2018.1492651DOI Listing

Biochemical, Histopathologic, and Genotoxic Effects of Ethanol Extract of Salvia hypargeia (Fisch. & Mey.) on Incisional and Excisional Wounded Diabetic Rats.

J Invest Surg 2019 Mar 25:1-13. Epub 2019 Mar 25.

i Department of Biology, Faculty of Arts and Science , Uşak University , Uşak , Turkey.

Purpose: Nonhealing wounds are a serious problem of diabetic patients. Salvia species are traditionally used for the treatment of wounds. The aim of the study was to investigate the effects of ointment prepared with ethanol extract obtained from the aerial parts of Salvia hypargeia, an endemic plant from Turkey, on diabetic rat incisional and excisional skin wounds. Read More

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http://dx.doi.org/10.1080/08941939.2019.1590483DOI Listing

Investigating the Role of Minimally Invasive Surgery in Patients with Chronic Pulmonary Disease.

J Invest Surg 2019 Mar 25:1-2. Epub 2019 Mar 25.

b Department of Surgery , Gynecologic Oncology Unit, Fondazione IRCCS Istituto Nazionale Tumori , Milan , Italy.

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http://dx.doi.org/10.1080/08941939.2019.1584653DOI Listing

C14orf166 Is a Biomarker for Predicting Hepatocellular Carcinoma Recurrence.

J Invest Surg 2019 Mar 24:1-10. Epub 2019 Mar 24.

a Department of Hepatobiliary Surgery , The Fifth Affiliated Hospital of Sun Yat-sen University , Zhuhai , China.

Aim: Chromosome 14 open reading frame 166 (C14orf166) acts as a transcriptional repressor and is correlated with centrosome architecture manipulation. Nevertheless, the function of C14orf166 in hepatocellular carcinoma (HCC) progression remains unclear. We aimed to investigate the role C14orf166 plays in HCC and further compared the prognostic value of C14orf166 with that of clinicopathological features. Read More

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https://www.tandfonline.com/doi/full/10.1080/08941939.2019.1
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http://dx.doi.org/10.1080/08941939.2019.1586015DOI Listing
March 2019
3 Reads

An Efficacy Comparison of Two Hemostatic Agents in a Porcine Liver Bleeding Model: Gelatin/Thrombin Flowable Matrix versus Collagen/Thrombin Powder.

J Invest Surg 2019 Mar 24:1-11. Epub 2019 Mar 24.

b Baxter Medical Products GmbH , Vienna , Austria.

Purpose: Management of bleeding during surgery can be aided by the application of topical hemostatic agents. This study compared the hemostatic efficacy of a new powder agent containing collagen, chondroitin sulfate, and thrombin (PCCT) with a flowable gelatin-thrombin matrix with smooth particles (SmGM) in a porcine liver bleeding model.

Materials And Methods: Lesions 4-6 mm deep and ∼10 mm in diameter were created in porcine livers and treated with either SmGM or PCCT. Read More

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http://dx.doi.org/10.1080/08941939.2019.1571130DOI Listing
March 2019
1 Read

Direct Peritoneal Resuscitation Reduces Lung Injury and Caspase 8 Activity in Brain Death.

J Invest Surg 2019 Mar 24:1-10. Epub 2019 Mar 24.

a Department of Surgery , University of Louisville , Louisville , KY , USA.

Background: Acute brain death (ABD) is associated with inflammation and lung injury. Direct peritoneal resuscitation (DPR) improves blood flow to the vital organs after ABD. DPR reduces lung injury, but the mechanism for this is unknown. Read More

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http://dx.doi.org/10.1080/08941939.2019.1579274DOI Listing

A Gene-Related Nomogram for Preoperative Prediction of Lymph Node Metastasis in Colorectal Cancer.

J Invest Surg 2019 Mar 24:1-8. Epub 2019 Mar 24.

a The First Department of General Surgery , Changzheng Hospital, Second Military Medical University , Shanghai , China.

Purpose: To develop and validate a gene-related nomogram for predicting the risk of lymph node (LN) metastasis preoperatively in patients with colorectal cancer (CRC).

Methods: RNA-seq data of 581 CRC and 51 normal cases with clinical features were downloaded from TCGA database. In the evaluation cohort with 381 CRC cases, the LASSO regression was used to reduce dimensionality of gene signatures extracted to build gene score. Read More

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http://dx.doi.org/10.1080/08941939.2019.1569738DOI Listing
March 2019
1 Read

Relationship Between Sagittal Balance and Axial Symptoms in Patients with Cervical Spondylotic Myelopathy Treated with Anterior Cervical Discectomy and Fusion.

J Invest Surg 2019 Mar 24:1-8. Epub 2019 Mar 24.

a Department of Orthopedic Surgery , The First Affiliated Hospital of Soochow University , Suzhou , Jiangsu , China.

Purpose: The purpose of this study was to investigate the sagittal balance of the cervical spine and the clinical outcomes of anterior cervical discectomy and fusion (ACDF) for the treatment of cervical spondylotic myelopathy and to explore whether sagittal balance is related to the incidence of postoperative axial symptoms.

Methods: Sixty-seven consecutive patients who underwent ACDF for the treatment of cervical spondylotic myelopathy from January 2014 to December 2016 were enrolled in our study. Sagittal balance parameters (global lordotic angle, segmented lordotic angle, T1 slope, and C2-7 sagittal vertical axis [C2-7 SVA] were recorded in the preoperative period and at 1 month, 3 months, and 1 year postoperatively. Read More

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http://dx.doi.org/10.1080/08941939.2018.1524948DOI Listing

Effects of Asiaticoside Treatment on the Survival of Random Skin Flaps in Rats.

J Invest Surg 2019 Mar 21:1-11. Epub 2019 Mar 21.

a Department of Orthopedics , People's Hospital of YingDe City Guangdong Province , Yingde City , China.

Background: Asiaticoside (AS) is extracted from the traditional herbal medicine Centella asiatica, and has angiogenic, antioxidant, anti-inflammatory, and wound-healing effects. We investigated the effects of AS on skin flap survival.

Methods: Dorsal McFarlane flaps were harvested from 36 rats and divided into two groups: an experimental group treated with 40 mg/kg AS administered orally once daily, and a control group administered normal saline in an identical manner. Read More

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http://dx.doi.org/10.1080/08941939.2019.1584255DOI Listing
March 2019
1 Read

Need For Whole Large Bowel Investigation in Sole Change in Bowel Habit: An Analysis of 719 Patients.

J Invest Surg 2019 Mar 21:1-6. Epub 2019 Mar 21.

a Department of Colorectal Surgery , West Suffolk Hospital , Suffolk , UK.

Purpose/Aim of the study: Patients referred for suspected colorectal cancer typically undergo whole large bowel investigation (WLBI) as per national guidelines. Sole change in bowel habit (CIBH) with no anemia/abdominal mass at time of referral has low oncological yield following diagnostic investigations, particularly for tumors proximal to the splenic flexure. Study aims were to evaluate cancer yield of patients referred for suspected colorectal cancer presenting with sole-symptom CIBH and to assess clinical and financial feasibility of a straight-to-test flexible sigmoidoscopy (FS). Read More

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http://dx.doi.org/10.1080/08941939.2019.1589606DOI Listing
March 2019
4 Reads

Quality of Care in Laparoscopic Cholecystectomy: Using Register Data Sensibly.

Authors:
Thomas Petzold

J Invest Surg 2019 Mar 21:1-2. Epub 2019 Mar 21.

a Medizinischer Dienst der Krankenversicherung im Freistaat Sachsen e V , Dresden , Germany.

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http://dx.doi.org/10.1080/08941939.2019.1579279DOI Listing

A Propensity Score-Matched Analysis of Laparoscopic versus Open Surgery in Patients with COPD.

J Invest Surg 2019 Mar 21:1-10. Epub 2019 Mar 21.

a Department of Surgery , Rutgers New Jersey Medical School , Newark , NJ , USA.

Purpose: This study aims to compare outcomes of laparoscopic surgery to the outcomes of open surgery in patients with chronic obstructive pulmonary disease (COPD). Plethora of studies compares laparoscopic and open surgery in the general population; however, there is a paucity of existing literature examining the optimal surgical techniques in the COPD population.

Materials And Methods: A propensity score-matched analysis using the 2012-2015 National Inpatient Sample (NIS) was conducted to match COPD patients undergoing the most common laparoscopic procedures to COPD patients undergoing the same procedures through an open approach. Read More

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http://dx.doi.org/10.1080/08941939.2019.1581307DOI Listing
March 2019
2 Reads

Enteral Immunonutrition Promotes Immune and Inflammatory Recovery after Surgery for Gastric Cancer.

J Invest Surg 2019 Mar 21:1-2. Epub 2019 Mar 21.

a Department of General Surgery, Peking Union Medical College Hospital , Chinese Academy of Medical Science & Peking Union Medical College , Beijing , China.

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http://dx.doi.org/10.1080/08941939.2019.1583295DOI Listing

Molecular and Biological Aspects of Self-Expandable Metallic Stent Placement in Malignant Colorectal Obstruction.

J Invest Surg 2019 Mar 21:1-3. Epub 2019 Mar 21.

a 2nd Department of Internal Medicine , Semmelweis University , Budapest , Hungary.

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http://dx.doi.org/10.1080/08941939.2019.1567879DOI Listing

Design of a Proficiency-Based Skills Training Curriculum for Our Newly Validated 3-Dimensional (3D) Laparoscopic Models, Using MISTELS.

J Invest Surg 2019 Mar 21:1-11. Epub 2019 Mar 21.

a Barts Cancer Institute , Queen Mary University of London , London , UK.

Aim: There are presently no courses or training curricula for surgical simulation that include training with 3-Dimensional (3D) laparoscopic platforms. Our aim is to create an expert led design of a proficiency-based skills training curriculum for our newly validated 3D laparoscopic models, using MISTELS compensating speed for precision and accuracy.

Method: In this study, 5 tasks were performed by 12 expert surgeons of different specializations on low-cost, portable models designed for 3D display. Read More

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http://dx.doi.org/10.1080/08941939.2019.1587113DOI Listing

Penetrating Pharyngoesophageal Injury: Practice Patterns in the Era of Nonoperative Management - A National Trauma Data Bank Review from 2007 to 2011.

J Invest Surg 2019 Mar 21:1-8. Epub 2019 Mar 21.

b Department of Surgery , University of Cape Town Health Sciences Faculty, Trauma Centre, Groote Schuur Hospital , Observatory , Cape Town , South Africa.

Introduction: Selective nonoperative management of neck injuries from penetrating mechanism has become an acceptable management strategy. We herein characterize current management strategies of cervical pharyngoesophageal injuries implemented by trauma surgeons in the United States.

Methods: The National Trauma Data Bank datasets 2007-2011 were queried for penetrating pharyngeal and/or cervical esophageal injuries. Read More

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http://dx.doi.org/10.1080/08941939.2019.1576810DOI Listing
March 2019
1 Read

Crescent Technique with Dual C-Shaped Reconstruction Plates for Posterior Acetabular Wall Fractures: An Invited Commentary.

J Invest Surg 2019 Mar 20:1-3. Epub 2019 Mar 20.

a Department of Orthopaedic Surgery , Third Hospital of Hebei Medical University , Shijiazhuang , China.

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http://dx.doi.org/10.1080/08941939.2018.1556365DOI Listing

A Quantitative Study of the Dimensional Change of Inferior Vena Cava on Computed Tomography During Acute Hemorrhage Shock in Swine.

J Invest Surg 2019 Mar 20:1-8. Epub 2019 Mar 20.

a Trauma Center of PLA, State Key Laboratory of Trauma, Burns and Combined Injury , Institute of Surgery Research, Daping Hospital, Army Medical University , Chongqing , China.

Background: The purpose of this study was to examine the dimensional change of IVC during acute hemorrhage through a volume-controlled acute hemorrhagic shock model in swine.

Methods: Volume-controlled hemorrhage was performed in 10 adult Bama mini pigs. Enhanced CT scan and hemodynamic monitoring were performed when the cumulative blood loss volume reached 0%, 10%, 20%, 30%, and 40%. Read More

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http://dx.doi.org/10.1080/08941939.2019.1567873DOI Listing
March 2019
1 Read
1.191 Impact Factor

The Effect of Hepcidin on Cardiac Ischemia-Reperfusion Injury.

J Invest Surg 2019 Mar 20:1-9. Epub 2019 Mar 20.

d Department of Physiology, Faculty of Medicine , İzmir Katip Çelebi University , İzmir , Turkey.

Background/aim: Hepcidin is the main hormone in the regulation of iron metabolism which is also released from the heart. The aim of our study was to investigate the effects of hepcidin on the cardiac ischemia-reperfusion injury.

Materials And Methods: In this study, 12 Wistar albino rats were divided into two groups (n = 6 each): 1) The ischemia-reperfusion group (Group 1); 2) Hepcidin-treated group (Group 2). Read More

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http://dx.doi.org/10.1080/08941939.2019.1579275DOI Listing

Lumbopelvic Fixation Versus Adjustable Plate for Unilateral Unstable Sacral Fractures.

J Invest Surg 2019 Mar 20:1-2. Epub 2019 Mar 20.

a Chief Orthopedic Department , General Hospital Agios Andreas , Patras , Greece.

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http://dx.doi.org/10.1080/08941939.2019.1570398DOI Listing

AJCC-8 TNM Staging System for Gastric Cancer. Is There a Scope for Improvement?

J Invest Surg 2019 Mar 20:1-2. Epub 2019 Mar 20.

c Department of Medical Oncology , The Mid Yorkshire Hospitals NHS Trust , Wakefield , UK.

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http://dx.doi.org/10.1080/08941939.2019.1579280DOI Listing
March 2019
1 Read
1.191 Impact Factor

Development of a Standardized Scoring System to Assess a Murine Model of Clostridium difficile Colitis.

J Invest Surg 2019 Mar 20:1-9. Epub 2019 Mar 20.

a Center for Perinatal Research, The Research Institute at Nationwide Children's Hospital, Department of Pediatric Surgery , Nationwide Children's Hospital , Columbus , OH , USA.

Background: Clostridium difficile infection is the most common cause of antimicrobial-associated diarrhea. Our aim was to introduce a novel and efficient clinical sickness score (CSS), and to define a detailed histologic injury score (HIS) in a murine model of C. difficile colitis. Read More

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http://dx.doi.org/10.1080/08941939.2019.1571129DOI Listing
March 2019
11 Reads

Does Wide Excisional Biopsy in Skin Cancer Prevent Finding The Real Sentinel Lymph Node?

J Invest Surg 2019 Mar 20:1-7. Epub 2019 Mar 20.

a Plastic, Reconstructive and Aesthetic Surgery Department , University of Health Sciences Sisli Hamidiye Etfal Training and Research Hospital , Istanbul , Turkey.

Purpose/Aim: The presence of nodal metastasis is an important prognostic factor for malignant melanoma and causes a 50% decrease in survival. Patients found not to have lymph node metastasis as a result of sentinel lymph node biopsy but develop regional lymph node metastasis in the follow-up period are called false negative sentinel. The hypothesis of this study was that excisional biopsy in patients with large lesions may change the lymphatic pathway and therefore cause false negative results. Read More

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http://dx.doi.org/10.1080/08941939.2018.1559898DOI Listing

Evaluation of Cholestyramine 15% Ointment in Relieving Pruritus and Burning After Ileostomy: A Rrandomized, Double-Blind Placebo-Controlled Clinical Trial.

J Invest Surg 2019 Mar 20:1-8. Epub 2019 Mar 20.

a Department of Clinical Pharmacy, Faculty of Pharmacy , Mazandaran University of Medical Sciences , Sari , Iran.

Purpose/Aims: Skin irritation is a common ileostomy problem that causes burning and pruritus among patients due to the leakage of intestinal discharge around the stoma. This clinical trial was performed to evaluate the efficacy of topical cholestyramine (15%) on the reduction of the levels of burning and pruritus after an ileostomy.

Material And Methods: The patients were randomly divided into two groups of treatment and control (n = 15). Read More

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http://dx.doi.org/10.1080/08941939.2019.1578442DOI Listing
March 2019
2 Reads
1.191 Impact Factor

Plating System Design Determines Mechanical Environment in Long Bone Mid-shaft Fractures: A Finite Element Analysis.

J Invest Surg 2019 Mar 19:1-10. Epub 2019 Mar 19.

a Department of Orthopaedic Surgery , The Third Hospital of Hebei Medical University , Shijiazhuang , People's Republic of China.

Purpose: Internal fixation device failure is rare but unavoidable. Fatigue-related mechanisms are responsible for most mechanical failures of orthopedic plates. Plate design needs to be optimized for both long fatigue life and bone healing. Read More

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http://dx.doi.org/10.1080/08941939.2019.1567875DOI Listing
March 2019
2 Reads

A Commentary on the Sensitivity and Specificity of the Platelet-Lymphocyte Ratio and Neutrophil-Lymphocyte Ratio in the Diagnosis of Acute Mesenteric Ischemia.

Authors:
Meer M Chisthi

J Invest Surg 2019 Mar 19:1-2. Epub 2019 Mar 19.

a Department of General Surgery , Government Medical College , Trivandrum , Kerala , India.

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http://dx.doi.org/10.1080/08941939.2019.1570397DOI Listing
March 2019
1 Read

The Presence of Thyroid Cartilage at the Surgical Level Reduces Early Dysphagia after Single-Level Anterior Cervical Surgery: A Retrospective Study.

J Invest Surg 2019 Mar 19:1-10. Epub 2019 Mar 19.

b Department of Orthopaedic Surgery , The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Zhejiang Spine Surgery Centre, , Wenzhou , PR China.

Background: Early dysphagia is a frequent complication of anterior cervical (AC) spine surgery. However, there are no reports that have discussed the correlation between early dysphagia and the positional relationship between thyroid cartilage and the surgical level.

Methods: We retrospectively enrolled 82 patients in our hospital who underwent single-level AC discectomy performed by the same surgeon using the same internal fixation apparatus from 2015 to 2017. Read More

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http://dx.doi.org/10.1080/08941939.2018.1520939DOI Listing
March 2019
1 Read

Higher Body Mass Index and Black Race Increase Risk of Rhabdomyolysis and Acute Kidney Injury After Trauma.

J Invest Surg 2019 Mar 19:1-2. Epub 2019 Mar 19.

a Department of Surgery , Morristown Medical Center , Morristown , NJ , USA.

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http://dx.doi.org/10.1080/08941939.2018.1502378DOI Listing
March 2019
1 Read

Ischemic Preconditioning on Liver Ischemia Reperfusion Injury: How Far is the Bedside from the Bench?

J Invest Surg 2019 Mar 19:1-2. Epub 2019 Mar 19.

b Department of Pathophysiology , Anhui Medical University , Hefei , China.

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http://dx.doi.org/10.1080/08941939.2019.1578443DOI Listing

Proposed Modification of the 8th Edition of the AJCC Staging System for Gastric Cancer.

J Invest Surg 2019 Mar 19:1-7. Epub 2019 Mar 19.

a Department of Gastrointestinal Surgery , Suzhou Municipal Hospital, Nanjing Medical University , Suzhou , China.

Background: The American Joint Committee on Cancer (AJCC) staging system has been the standardized staging system for malignancies since the first edition in 1987. The 8th edition of gastric cancer was released in 2016, and is expected to be used in clinical practice in 2018. The aim of this study was to improve this new gastric cancer staging system. Read More

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https://www.tandfonline.com/doi/full/10.1080/08941939.2018.1
Publisher Site
http://dx.doi.org/10.1080/08941939.2018.1544325DOI Listing
March 2019
3 Reads

Lumbopelvic Fixation Versus Novel Adjustable Plate for Sacral Fractures: A Retrospective Comparative Study.

J Invest Surg 2019 Mar 19:1-9. Epub 2019 Mar 19.

a Department of Orthopaedic Surgery , Third Hospital of Hebei Medical University , Shijiazhuang , Hebei, China.

Purpose: The purpose of this study is to compare the therapeutic effects of the lumbopelvic technique and a novel adjustable plate for sacral fractures.

Materials And Methods: Patients with unilateral sacral fractures fixed via the lumbopelvic technique or using a novel adjustable plate from June 2011 to June 2017 were recruited into this study and were divided into two groups: group A (lumbopelvic fixation) and group B (novel adjustable plate). Surgical time, intraoperative blood loss, frequency of intraoperative fluoroscopy, reduction quality, and related complications were reviewed. Read More

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http://dx.doi.org/10.1080/08941939.2019.1569737DOI Listing

The Efficacy and Safety of Combined Adductor Canal Block with Periarticular Anesthetic Injection Following Primary Total Knee Arthroplasty: A Meta-Analysis.

J Invest Surg 2019 Mar 19:1-10. Epub 2019 Mar 19.

a Department of Orthopaedics , The First People's Hospital of Changzhou , Changzhou , Jiangsu Province , China.

Objective: Recently, there has been an increasing interest in combined adductor canal block (ACB) with periarticular anesthetic injection (PAI) as a technique to control postoperative pain in total knee arthroplasty (TKA). This study evaluated the analgesic efficacy and safety of the combined therapy for early postoperative pain treatment after TKA.

Methods: From the inception to July 2018, two independent investigators used the following electronic databases to search existing literature: PubMed, Embase, Medline, and Web of Science. Read More

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http://dx.doi.org/10.1080/08941939.2019.1579278DOI Listing

Is Ketamine Suitable for Use in Glutamate Toxicity Conditions?: An In Vitro Study.

J Invest Surg 2019 Mar 19:1-8. Epub 2019 Mar 19.

b Department of Anesthesia and Reanimation, Erzurum Regional Training and Research Hospital , Turkey Health Sciences University , Erzurum , Turkey.

Ketamine is an anesthetic agent with sedative and analgesic properties frequently used in surgery. However, particular anesthetic substances need to be applied for different diseases and surgical procedures. Can ketamine be used in all operations and in all patients with an additional disease? The purpose of this study was to determine the neurotoxic or neuroprotective effects of different dosages of ketamine in a glutamate-derived toxicity model in olfactory, cortex and cerebellum cell cultures. Read More

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http://dx.doi.org/10.1080/08941939.2019.1582739DOI Listing
March 2019
1 Read

Sensitivity and Specificity of the Platelet-Lymphocyte Ratio and the Neutrophil-Lymphocyte Ratio in Diagnosing Acute Mesenteric Ischemia in Patients Operated on for the Diagnosis of Mesenteric Ischemia: A Retrospective Case-Control Study.

J Invest Surg 2019 Mar 19:1-8. Epub 2019 Mar 19.

a Department of General Surgery, Faculty of Medicine , Ataturk University , Erzurum , Turkey.

Aim: The present study aims to determine whether various hematological parameters and ratios of patients could be used to diagnose AMI.

Materials And Methods: The subjects of the study are the patients who were hospitalized with an acute mesenteric ischemia (AMI) pre-diagnosis and underwent surgery as a consequence. The patients who were determined to have the diagnosis of AMI intraoperatively are categorized in the AMI Group. Read More

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https://www.tandfonline.com/doi/full/10.1080/08941939.2019.1
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http://dx.doi.org/10.1080/08941939.2019.1566418DOI Listing
March 2019
5 Reads

Short-Term Outcomes of Self-Expandable Metallic Stent versus Decompression Tube for Malignant Colorectal Obstruction: A Meta-Analysis of Clinical Data.

J Invest Surg 2019 Mar 19:1-9. Epub 2019 Mar 19.

a Department of general surgery, Beijing Tiantan Hospital , Capital Medical University , Beijing , China.

Purpose: To compare the short-term outcomes between self-expandable metallic stent (SEMS) and decompression tubes (DT) for malignant colorectal obstruction.

Methods: A comprehensive literature search was performed from inception to 2018/12/6 covering Pubmed, Embase, and Cochrane library. Methodological assessments of eligible studies were performed by using Newcastle-Ottawa Scale (NOS). Read More

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http://dx.doi.org/10.1080/08941939.2019.1566419DOI Listing
March 2019
5 Reads

The Impact of a Surgical Unit's Structure and Operative Technique on Quality in Two Swedish Rural Hospitals.

J Invest Surg 2019 Mar 19:1-6. Epub 2019 Mar 19.

a Department of Surgical and Perioperative Sciences , Umeå University/Östersund , Umeå , Sweden.

Introduction: Laparoscopic cholecystectomy (LC) is a commonly performed surgical procedure with a low complication rate. It is performed either as an acute or as an elective procedure. Most elective LCs are performed on nonlethal diseases and this is why good quality is important. Read More

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http://dx.doi.org/10.1080/08941939.2019.1579277DOI Listing

Modifiable Factors as Current Smoking, Hypoalbumin, and Elevated Fasting Blood Glucose Level Increased the SSI Risk Following Elderly Hip Fracture Surgery.

J Invest Surg 2019 Mar 19:1-9. Epub 2019 Mar 19.

a Department of Orthopaedic Surgery , The General Hospital of Jizhong Energy Xingtai Mining Group , Xingtai , Hebei , P. R China.

Objective: Surgical site infection (SSI) following hip fractures represents an important complication. This study aimed to investigate the incidence rate after surgery of hip fractures in the elderly and to identify the associated risk factors.

Patients: Patients' demographic, injury, and surgery-related data and biochemical indexes were retrospectively reviewed and recorded during their hospitalization, between July 2015 and June 2017. Read More

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https://www.tandfonline.com/doi/full/10.1080/08941939.2018.1
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http://dx.doi.org/10.1080/08941939.2018.1556364DOI Listing
March 2019
15 Reads

Effect of Enteral Immunonutrition on Immune, Inflammatory Markers and Nutritional Status in Gastric Cancer Patients Undergoing Gastrectomy: A Randomized Double-Blinded Controlled Trial.

J Invest Surg 2019 Mar 19:1-10. Epub 2019 Mar 19.

c Department of Gastrointestinal Surgery , West China Hospital, Sichuan University , Chengdu , China.

Backgrounds: Enteral immunonutrition (EIN) has received increasing attention, however, evidence on its immunomodulatory and anti-inflammatory function in gastric cancer patients undergoing gastrectomy is poorly investigated. Objectives of this study were to evaluate the effect of EIN on immune function, inflammation response and nutrition status when compared to standard enteral nutrition (SEN).

Methods: Totally 124 gastric cancer patients after gastrectomy were randomized to receive early 5-days postoperative EIN (formula enriched with arginine, glutamine, omega-3 fatty acids and nucleotide), or SEN. Read More

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https://www.tandfonline.com/doi/full/10.1080/08941939.2019.1
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http://dx.doi.org/10.1080/08941939.2019.1569736DOI Listing
March 2019
11 Reads
1.191 Impact Factor