27,577,210 results match your criteria Journal of Infectious Diseases and Immunity [Journal]

  • Page 1 of 551545

Radiologic and Intraoperative Finding of Intimal Tear in Type A Intramural Hematoma of the Aorta.

Aorta (Stamford) 2018 Jun 22;6(3):92-93. Epub 2019 Feb 22.

Unit of Cardiac Surgery, University of Palermo, Palermo, Italy.

Aortic intramural hematoma (IMH) is described as "dissection without intimal tear" due to rhexis of vasa vasorum, which results in bleeding within the tunica media in the absence of intimal disruption or blood flow communication. The aim of our study is to validate perioperative evidence of intimal entry tear in IMH patients and to suggest that this entity may represent a part of a disease and not a separate disease. Read More

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http://dx.doi.org/10.1055/s-0039-1678569DOI Listing

Rare Case of Surgical Treatment of a Giant Aortic Arch False Aneurysm.

Aorta (Stamford) 2018 Jun 22;6(3):88-91. Epub 2019 Feb 22.

Department of Vascular Surgery, City Multiservice Hospital No. 2, Saint Petersburg, Russia.

The authors present a clinical case of a 44-year-old male patient with a chronic giant aortic arch pseudoaneurysm with a diameter of 136 × 72 mm. The open resection of false aneurysm was accomplished without artificial circulation. Repair was performed with temporary ascending-to-descending and brachiocephalic bypass without cardiopulmonary bypass. Read More

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http://dx.doi.org/10.1055/s-0039-1678553DOI Listing

Blood Flow after Endovascular Repair in the Aortic Arch: A Computational Analysis.

Aorta (Stamford) 2018 Jun 22;6(3):81-87. Epub 2019 Feb 22.

Thoracic Aortic Research Center, IRCCS-Policlinico San Donato, University of Milan, Milan, Italy.

Background:  The benefits of thoracic endovascular aortic repair (TEVAR) have encouraged stent graft deployment more proximally in the aortic arch. This study quantifies the hemodynamic impact of TEVAR in proximal landing zone 2 on the thoracic aorta and the proximal supra-aortic branches.

Methods:  Patients treated with TEVAR in proximal landing zone 2 having available preoperative and 30-day postoperative computer tomography angiography and phase-contrast magnetic resonance imaging data were retrospectively selected. Read More

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http://dx.doi.org/10.1055/s-0039-1683771DOI Listing

Quadrangular Fixation of Pectus Bars to Prevent Displacement in Nuss Procedure.

Thorac Cardiovasc Surg 2019 Feb 22. Epub 2019 Feb 22.

Department of Anesthesiology, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Background:  Double pectus bars are sometimes inserted to correct pectus excavatum. Method of double-bar fixation to prevent bar displacement has been rarely reported. We have used quadrangular fixation of the double pectus bars. Read More

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http://dx.doi.org/10.1055/s-0039-1678695DOI Listing
February 2019

Thymic Epithelial Tumors: Prognostic Significance and Relationship between Histology and the New TNM Staging System.

Thorac Cardiovasc Surg 2019 Feb 22. Epub 2019 Feb 22.

Department of Morfology, Experimental Medicine and Surgery, Section of General and Thoracic Surgery, Sant'Anna Hospital, University of Ferrara, Ferrara, Italy.

Background:  This study aims to describe the relationship between the new tumor nodes metastasis (TNM) staging and World Health Organization (WHO) classification and to identify how these two variables relate to each other and whether they possess a prognostic value in predicting survival and recurrence of disease.

Methods:  Medical records of 54 patients who underwent surgery for thymic epithelial tumors between 1996 and 2015 were reviewed.The histologic type of neoplasm was classified according to the criteria of WHO and staging was evaluated using the new TNM classification system. Read More

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http://dx.doi.org/10.1055/s-0039-1678612DOI Listing
February 2019

Influence of Luminal Communication on Aortic Enlargement after Hemiarch Replacement for Acute Type A Aortic Dissection.

Thorac Cardiovasc Surg 2019 Feb 22. Epub 2019 Feb 22.

Department of Cardiovascular Surgery, Matsubara Tokushukai Hospital, Osaka, Japan.

Background:  Aortic enlargement after hemiarch replacement (HAR) for acute type A aortic dissection (AAAD) is a serious problem. We reviewed our experience and analyzed the risk factors for aortic enlargement.

Methods:  During April 2005 to December 2017, 364 patients underwent HAR for AAAD. Read More

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http://dx.doi.org/10.1055/s-0039-1677886DOI Listing
February 2019

[Chylothorax: Current Therapeutic Options].

Zentralbl Chir 2019 Feb 22. Epub 2019 Feb 22.

Radiologische Klinik, Universitätsklinikum Bonn, Deutschland.

Therapeutic options in management of chylothorax encompass conservative, surgical and also interventional measures. Despite the fact that interventions have been performed in substantial numbers of patients - particularly thoracic duct embolisations - general knowledge about this therapeutic option is still limited. Therefore, this article gives an overview of the state of the art for therapeutic options, also emphasising radiological/interventional procedures. Read More

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http://dx.doi.org/10.1055/a-0831-2649DOI Listing
February 2019

[Impact of Selective Quality of Life Analysis in Patients with Local Hyperhidrosis after Sympathicus Clipping].

Zentralbl Chir 2019 Feb 22. Epub 2019 Feb 22.

Thoraxchirurgische Abteilung in der Chirurgischen Klinik, Universitätsklinikum, Friedrich-Alexander-Universität Erlangen-Nürnberg, Deutschland.

Introduction: Hyperhidrosis (HH) is associated with physical and psychological restrictions. The treatment includes both conservative and surgical methods and aims to permanently improve the quality of life (QoL) of those affected. Endoscopic sympathetic blockade (ESB) is an established surgical therapeutic method and is considered effective when conservative treatment options fail. Read More

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http://dx.doi.org/10.1055/a-0808-5003DOI Listing
February 2019

[Risk Factors for Permanent Postoperative Hypoparathyreoidism].

Zentralbl Chir 2019 Feb 22. Epub 2019 Feb 22.

Klinik für Allgemein- u. Viszeralchirurgie mit Sektion Proktologie, Raphaelsklinik Münster, Deutschland.

Background: Permanent postoperative hypoparathyreoidism remains the most frequent complication after total thyreoidectomy with severe long-term morbidity, impairment of quality of life and economic implications.

Objective: Identification of risk factors for permanent postoperative hypoparathyreoidism.

Material And Methods: 420 patients received total thyreoidectomy in our endocrine centre between 08/2012 und 08/2014, of whom 382 were included in the study. Read More

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http://dx.doi.org/10.1055/a-0837-1013DOI Listing
February 2019

[Development of a Rehab-Wiki for rehabilitation-Related Educational Materials Assigned to Competence-Based Learning Objectives].

Rehabilitation (Stuttg) 2019 Feb 22. Epub 2019 Feb 22.

Institut für Rehabilitationsmedizin der Martin-Luther-Universität Halle-Wittenberg.

Purpose: For adequate rehabilitative care, it is indispensable to impart appropriate competences in medical education based on learning objectives. In addition to the "National Competence-Based Learning Objectives Catalogue for Medicine (NKLM)", a competence-based learning objectives catalogue for the field of rehabilitation in the interdisciplinary subject "Rehabilitation, Physical Medicine, Naturopathy" (RPMN) was recently presented. These learning objectives were to be assigned to a wide variety of teaching materials of different media types and made easily accessible to university lecturers in a free online database. Read More

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http://dx.doi.org/10.1055/a-0847-7344DOI Listing
February 2019

Phonological Treatment Options for Children with Expressive Language Impairment.

Authors:
Jill R Hoover

Semin Speech Lang 2019 Mar 22;40(2):138-148. Epub 2019 Feb 22.

Department of Communication Disorders, University of Massachusetts Amherst, Amherst, Massachusetts.

The vast majority of treatment efficacy research in the area of phonology focuses on issues relevant to children who have significant limitations in productive phonology but are "typically developing" in most other ways. The base of evidence to guide clinicians on planning intervention for children with phonological and cooccurring expressive language difficulties (PD + LI) is less well developed. Thus, the goal of this paper is to summarize the evidence on two treatment procedures designed to facilitate growth in phonological inventory for children who also require direct intervention to target other aspects of expressive language. Read More

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http://dx.doi.org/10.1055/s-0039-1677764DOI Listing

Speech Sound Disorder and Visual Biofeedback Intervention: A Preliminary Investigation of Treatment Intensity.

Semin Speech Lang 2019 Mar 22;40(2):124-137. Epub 2019 Feb 22.

Department of Communication Sciences and Disorders, Montclair State University, Bloomfield, New Jersey.

A growing body of research suggests that cases of speech sound errors that have not responded to previous intervention can sometimes be eliminated through speech therapy incorporating visual biofeedback. Aside from considerations related to the specific biofeedback type, acquisition and generalization of a motor plan may be linked to treatment intensity. Several researchers have raised the possibility that inadequate dosage levels may present a significant barrier to success. Read More

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http://dx.doi.org/10.1055/s-0039-1677763DOI Listing
March 2019
1 Read

Innovative Service Delivery Models for Serving Children with Speech Sound Disorders.

Semin Speech Lang 2019 Mar 22;40(2):113-123. Epub 2019 Feb 22.

Department of Speech, Language, and Hearing Sciences, Purdue University, West Lafayette, Indiana.

Service delivery variables that may have an impact on the treatment outcomes of children with speech sound disorders include the number and duration of intervention sessions, distribution of the sessions over time, and the format (group intervention or individual intervention). In this article, we briefly review these variables and the recommendations for the most effective service delivery components for children with speech sound disorders. We then describe innovative, collaborative service delivery models for preschoolers and school-age children with speech sound disorder. Read More

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http://dx.doi.org/10.1055/s-0039-1677762DOI Listing

Describing How School-Based SLPs Determine Eligibility for Children with Speech Sound Disorders.

Semin Speech Lang 2019 Mar 22;40(2):105-112. Epub 2019 Feb 22.

Crane Center for Early Childhood Research and Policy, The Ohio State University, Columbus, Ohio.

The purpose of this study was to explore how school-based speech-language pathologists (SLPs) determine eligibility for children with speech sound disorders (SSDs). Presently, there is substantial variability nationwide with respect to if or how children with SSDs receive speech therapy in public schools. We report the results of a nation-wide survey of school-based SLPs, which further underscore this variability. Read More

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http://dx.doi.org/10.1055/s-0039-1677761DOI Listing

What Do Children with Speech Sound Disorders Think about Their Talking?

Semin Speech Lang 2019 Mar 22;40(2):94-104. Epub 2019 Feb 22.

School of Teacher Education, Charles Sturt University, Australia.

Investigating children's feelings and attitudes toward talking assists speech-language pathologists (SLPs) to understand experiences of communication and the impact of speech sound disorders (SSD). This, in turn, can assist SLPs in identifying appropriate intervention for children with SSD that addresses the needs of children, and their communication partners. This paper draws on data from the Sound Start Study in Australia to explore the attitudes toward talking of 132 preschool-aged children with SSD and the relationship between children's attitudes, speech accuracy, and parent-reported intelligibility and participation. Read More

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http://dx.doi.org/10.1055/s-0039-1677760DOI Listing

Clinical Challenges: Assessing Toddler Speech Sound Productions.

Authors:
Shari L DeVeney

Semin Speech Lang 2019 Mar 22;40(2):81-93. Epub 2019 Feb 22.

Department of Special Education and Communication Disorders, University of Nebraska at Omaha, Omaha, Nebraska.

When assessing toddler speech sound productions, speech-language pathologists (SLPs) must be mindful of several important but not insurmountable limitations inherent to working with this young population for whom speech sound production may be of concern. These limitations include: (1) inconsistencies in recommended connected speech sampling size and phonetic transcription accuracy, (2) the prevalence of typical intraword variability for toddlers, (3) limited information regarding the reliability of informal measures of analysis, and (4) irregularities in available normative data for referencing speech sound development and mastery. This article includes a discussion of these factors, an overview of key assessment tools for single-word and connected-speech sampling, advice for current evidence-based practice procedures, and a thorough but not exhaustive listing of opportunities to improve clinical practice in this area. Read More

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http://dx.doi.org/10.1055/s-0039-1677759DOI Listing

Speech Sound Disorders in Children.

Authors:
Katy Cabbage

Semin Speech Lang 2019 Mar 22;40(2):79-80. Epub 2019 Feb 22.

Department of Communication Disorders, Brigham Young University, Provo, Utah.

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http://dx.doi.org/10.1055/s-0039-1677758DOI Listing

Anterolateral Thigh Flap in a Chicken Model: A Novel Perforator Training Model.

J Reconstr Microsurg 2019 Feb 22. Epub 2019 Feb 22.

Department of Human Pathology of the Adult, the Child and the Adolescent, University of Messina, Messina, Italy.

Background:  Preclinical training in perforator flap harvesting is typically conducted on living animal models; however, repeated training is not possible with these models because of ethical and/or economical constraints. We describe an anterolateral thigh flap (ALT flap) training model using chicken thigh that seems to be an appropriate training model prior, for example, to raise a perforator flap in a living rat or swine model.

Methods:  A total of 10 chicken legs were used in this study. Read More

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http://dx.doi.org/10.1055/s-0039-1679882DOI Listing
February 2019

Accuracy of Routine Prenatal Genetic Screening in Patients Referred for Genetic Counseling.

Am J Perinatol 2019 Feb 22. Epub 2019 Feb 22.

Department of Obstetrics and Gynecology, Christiana Care Health System, Newark, Delaware.

Objective:  The American College of Obstetricians and Gynecologists (ACOG) guidelines recommend routine prenatal screening for genetic diseases that could affect the pregnancy. We sought to determine the rate of missed genetic information in the general obstetrician's routine prenatal genetic screening process.

Study Design:  This is a sequential case series of women referred for genetic counseling between March and August of 2015. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1678533
Publisher Site
http://dx.doi.org/10.1055/s-0039-1678533DOI Listing
February 2019
1 Read

Effect of Aflibercept on Cystoid Macular Edema Associated with Central Retinal Vein Occlusion. Results from a District Hospital in the United Kingdom.

Klin Monbl Augenheilkd 2019 Feb 22. Epub 2019 Feb 22.

Department of Ophthalmology, The Ipswich Hospital NHS Trust (affiliated to the University of Cambridge), Ipswich, Suffolk, UK.

Purpose: The purpose of this study was to report the efficiency and safety of intravitreal aflibercept for the treatment of cystoid macular edema (CME) secondary to central retinal vein occlusion (CRVO).

Methods: This is a retrospective cohort study. Ten naive eyes of ten patients with CME secondary to CRVO were included. Read More

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http://dx.doi.org/10.1055/a-0786-7872DOI Listing
February 2019

Predicting the Quality of Warfarin Therapy: Reframing the Question.

Thromb Haemost 2019 Feb 22. Epub 2019 Feb 22.

Department of Internal Medicine, Frankel Cardiovascular Center, University of Michigan, Ann Arbor, Michigan, United States.

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http://dx.doi.org/10.1055/s-0039-1681060DOI Listing
February 2019

S3-Leitlinienreport – Colitis ulcerosa.

Z Gastroenterol 2018 Sep 22;56(9):e181-e459. Epub 2019 Feb 22.

Klinik für Allgemeine Innere Medizin und Gastroenterologie, Klinikum Lüneburg, Lüneburg, Germany.

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http://dx.doi.org/10.1055/a-0651-3773DOI Listing
September 2018

The Neuroprotective Peptide PACAP1-38 Contributes to Horizontal Cell Development in Postnatal Rat Retina.

Invest Ophthalmol Vis Sci 2019 Feb;60(2):770-778

Department of Experimental Zoology and Neurobiology, University of Pécs, Pécs, Hungary.

Purpose: PACAP1-38, a member of the secretin/glucagon superfamily, is expressed in the developing retina with documented neuroprotective effects. However, its function in retinal cell differentiation has yet to be elucidated. Our goals, therefore, were to identify PAC1 expressing cells morphologically, investigate the PACAP1-38 action functionally, and establish PACAP1-38 regulated events developmentally during the first postnatal week in rat retina. Read More

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http://dx.doi.org/10.1167/iovs.18-25719DOI Listing
February 2019

Back cover.

Authors:

Nanoscale 2019 Feb 21;11(8):3758. Epub 2019 Feb 21.

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http://dx.doi.org/10.1039/C9NR90047KDOI Listing
February 2019

Inside back cover.

Authors:

Nanoscale 2019 Feb 21;11(8):3757. Epub 2019 Feb 21.

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http://dx.doi.org/10.1039/C9NR90046BDOI Listing
February 2019

Contents list.

Authors:

Nanoscale 2019 Feb 21;11(8):3403-3413. Epub 2019 Feb 21.

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http://dx.doi.org/10.1039/C9NR90045DDOI Listing
February 2019

Inside front cover.

Authors:

Nanoscale 2019 Feb 21;11(8):3402. Epub 2019 Feb 21.

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http://dx.doi.org/10.1039/C9NR90044FDOI Listing
February 2019

Front cover.

Authors:

Nanoscale 2019 Feb 21;11(8):3401. Epub 2019 Feb 21.

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http://dx.doi.org/10.1039/C9NR90043HDOI Listing
February 2019

Multisite measurement of regional oxygen saturation in Fontan patients with or without protein-losing enteropathy at rest and during exercise.

Pediatr Res 2019 Feb 22. Epub 2019 Feb 22.

Department of Pediatric Cardiology, University of Erlangen-Nuernberg, Loschgestraße 15, 91054, Erlangen, Germany.

Background: Protein-losing enteropathy (PLE) is a severe complication of Fontan circulation with increased risk of end-organ dysfunction. We evaluated tissue oxygenation via near-infrared spectroscopy (NIRS) at different exercise levels in Fontan patients.

Materials And Methods: Assessment of multisite NIRS during cycle ergometer exercise and daily activities in three groups: Fontan patients with PLE; without PLE; patients with dextro-transposition of the great arteries (d-TGA); comparing univentricular with biventricular circulation and Fontan with/without PLE. Read More

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http://dx.doi.org/10.1038/s41390-019-0346-3DOI Listing
February 2019

Ethanol-induced conditioned place preference and aversion differentially alter plasticity in the bed nucleus of stria terminalis.

Neuropsychopharmacology 2019 Feb 22. Epub 2019 Feb 22.

Department of Pharmacology, Bowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Thurston Bowles Building 104 Manning Drive, Chapel Hill, NC, 27599, USA.

Contextual cues associated with drugs of abuse, such as ethanol, can trigger craving and drug-seeking behavior. Pavlovian procedures, such as place conditioning, have been widely used to study the rewarding/aversive properties of drugs and the association between environmental cues and drug seeking. Previous research has shown that ethanol as an unconditioned stimulus can induce a strong conditioned place preference (CPP) or aversion (CPA) in rodents. Read More

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http://dx.doi.org/10.1038/s41386-019-0349-0DOI Listing
February 2019

Density of small dendritic spines and microtubule-associated-protein-2 immunoreactivity in the primary auditory cortex of subjects with schizophrenia.

Neuropsychopharmacology 2019 Feb 22. Epub 2019 Feb 22.

Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.

Previously, we demonstrated that dendritic spine density (DSD) in deep layer 3 of the primary auditory cortex (A1) lower, due to having fewer small spines, in subjects with schizophrenia (SZ) than non-psychiatric control (NPC) subjects. We also previously demonstrated that microtubule-associated-protein-2 immunoreactivity (MAP2-IR) in A1 deep layer 3 is lower, and positively correlated with DSD, in SZ subjects. Here, we first sought to confirm these findings in an independent cohort of 25 SZ-NPC subject pairs (cohort 1). Read More

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http://dx.doi.org/10.1038/s41386-019-0350-7DOI Listing
February 2019

Optimising the biocompatibility of 3D printed photopolymer constructs in vitro and in vivo.

Biomed Mater 2019 Feb 22. Epub 2019 Feb 22.

Department of Surgery, University of Melbourne Faculty of Medicine Dentistry and Health Sciences, Melbourne, Victoria, AUSTRALIA.

3D printing is a rapid and accessible fabrication technology that engenders creative custom design solutions for cell scaffolds, perfusion systems and cell culture systems for tissue engineering. Critical to its success is the biocompatibility of the materials used, which should allow long-term tissue culture without affecting cell viability or inducing an inflammatory response for in vitro and in vivo applications. Polyjet 3D printers offer arguably the highest resolution with the fewest design constraints of any commercially available 3D printing systems. Read More

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http://dx.doi.org/10.1088/1748-605X/ab09c4DOI Listing
February 2019

A simplified fabrication technique for cellularized high-collagen dermal equivalents.

Biomed Mater 2019 Feb 22. Epub 2019 Feb 22.

Product Development Group Zurich, Eidgenossische Technische Hochschule Zurich Departement Maschinenbau und Verfahrenstechnik, Zurich, ZH, SWITZERLAND.

Human autologous bioengineered skin has been successfully developed and used to treat skin injuries in a growing number of cases. In current clinical studies, the biomaterial used is fabricated via plastic compression of collagen hydrogel to increase the density and stability of the tissue. To further facilitate clinical adoption of bioengineered skin, the fabrication technique needs to be improved in terms of standardization and automation. Read More

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http://dx.doi.org/10.1088/1748-605X/ab09c5DOI Listing
February 2019

Advanced nanostructures for cell membrane poration.

Nanotechnology 2019 Feb 22. Epub 2019 Feb 22.

Mechanical Engineering, University of Colorado Boulder, ECES 158, Boulder, Colorado, 80309-0401, UNITED STATES.

Nanostructured devices have been able to foster the technology for cell membrane poration. With the size smaller than the cell, nanostructure allows efficient poration on the cell membrane. Emerging nanostructures with various physical transduction have been demonstrated to accommodate effective intracellular delivery. Read More

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http://dx.doi.org/10.1088/1361-6528/ab096bDOI Listing
February 2019

From qualitative to quantitative description of the anomalous thermoelastic behavior of V, Nb, Ta, Pd and Pt.

J Phys Condens Matter 2019 Feb 22. Epub 2019 Feb 22.

Materials Chemistry, Rheinisch - Westfalische Technische Hochschule Aachen, Aachen, GERMANY.

To study the anomalous thermoelastic behavior of bcc V, Nb, Ta as well as fcc Pd and Pt a density functional theory based model is used, which allows for the calculation of the elastic constant c' and c<sub>44</sub> as a function of temperature. Available experimental c<sub>44</sub> trends are correctly reproduced indicating that the electronic structure mechanisms enabling anomalous behavior are captured by the model. A density functional theory based correlative investigation between V, Nb, Ta, Pd and Pt with anomalous thermoelastic properties and Mo and Cu with ordinary behavior reveals a high density of states at the Fermi level to be a necessary but not sufficient condition for an anomalous thermoelastic behavior. Read More

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http://dx.doi.org/10.1088/1361-648X/ab099bDOI Listing
February 2019

Quantum transport through the edge states of zigzag phosphorene nanoribbons in presence of a single point defect: analytic Green's function method.

J Phys Condens Matter 2019 Feb 22. Epub 2019 Feb 22.

University of Isfahan, Isfahan, Isfahan, Iran (the Islamic Republic of).

Zigzag phosphorene nanoribbons have quasi-flat band edge modes entirely detached from the bulk states. We analytically study the electronic transport through such edge states in the presence of a localized defect for semi-infinite and finite ribbon widths. Using the tight-binding model, we derive analytical expressions for the Green's function and transmission amplitude of both pristine and defective nanoribbons. Read More

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http://dx.doi.org/10.1088/1361-648X/ab09b8DOI Listing
February 2019

High-temperature superconductivity in ternary clathrate YCaH12 under high pressures.

J Phys Condens Matter 2019 Feb 22. Epub 2019 Feb 22.

State Key Laboratory of Superhard Materials, Jilin University, Changchun, 130012, P.R.CHINA, Changchun, CHINA.

Binary hydrogen-rich compounds with H clathrate structures can serve as high-temperature superconductors under high pressures. Here, a novel ternary clathrate structure YCaH<sub>12</sub> with space group <i>Pm</i>-3<i>m</i> is uncovered at high pressure using ab initio methods. It is predicted that YCaH<sub>12</sub> can be stable above 180 GPa and decomposes into YH<sub>6</sub> and CaH<sub>6</sub> above 257 GPa. Read More

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http://dx.doi.org/10.1088/1361-648X/ab09b4DOI Listing
February 2019

Benchmark of different assessment methods for non-sinusoidal magnetic field exposure in the context of European Directive 2013/35/EU.

J Radiol Prot 2019 Feb 22. Epub 2019 Feb 22.

Department of Physics, Aristotle University of Thessaloniki, University Campus, Thessaloniki, 54124, GREECE.

For the assessment of non-sinusoidal magnetic fields the European EMF Directive 2013/35/EU specified the Weighted Peak Method in Time Domain (WPM-TD) as the reference method. However, also other scientifically validated methods are allowed, provided that they lead to approximately equivalent and comparable results. In the non-binding guide for practical implementation of 2013/35/EU three methods alternative to the WPM-TD are described, i. Read More

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http://dx.doi.org/10.1088/1361-6498/ab0988DOI Listing
February 2019

Fiducial marker based intra-fraction motion assessment on cine-MR for MR-Linac treatment of prostate cancer.

Phys Med Biol 2019 Feb 22. Epub 2019 Feb 22.

Department of Radiotherapy, Universitair Medisch Centrum Utrecht, Utrecht, NETHERLANDS.

Purpose We have developed a method to determine intrafraction motion of the prostate through automatic fiducial marker (FM) tracking on 3D cine-magnetic resonance (MR) images with high spatial and temporal resolution. Methods Twenty-nine patients undergoing prostate stereotactic body radiotherapy (SBRT), with four implanted cylindrical gold FMs, had cine-MR imaging sessions after each of five weekly fractions. Each cine-MR examination consisted of 55 sequentially obtained 3D datasets ('dynamics'), acquired over a 11 second period, covering a total of 10 minutes. Read More

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http://dx.doi.org/10.1088/1361-6560/ab09a6DOI Listing
February 2019

Individual radiation protection: idea and research needs.

J Radiol Prot 2019 Feb 22. Epub 2019 Feb 22.

Deputy Director General Office, Federal Authority for Nuclear Regulation (FANR), The Landmark Tower Al Markaziyah West - Abu Dhabi Corniche - First Floor Abu Dhabi, United Arab Emirates, Abu Dhabi, Abu Dhabi, 112021, UNITED ARAB EMIRATES.

The current Radiation Protection System is based on the definition and use of the "effective dose", a complex quantity which is not measurable and normally not easily understood by the general public. National radiation protection requirements and regulations stem from a few basic principles, one of which is the respect of individual annual dose limits, specified in terms of the quantities "effective dose" and "equivalent dose". Another guiding principle is the continuous quest for optimization of individual integrated doses, i. Read More

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http://dx.doi.org/10.1088/1361-6498/ab0979DOI Listing
February 2019

Lateral heterostructures and one-dimensional interfaces in 2D transition metal dichalcogenides.

J Phys Condens Matter 2019 Feb 22. Epub 2019 Feb 22.

Department of Physics and Astronomy, Ohio University, 251 Clippinger Laboratories, Athens, Ohio, 45701, UNITED STATES.

The growth and exfoliation of two-dimensional (2D) materials have led to the creation of edges and novel interfacial states at the juncture between crystals with different composition or phases. These hybrid heterostructures (HSs) can be built as vertical van der Waals \textit{stacks}, resulting in a 2D interface, or as \textit{stitched} adjacent monolayer crystals, resulting in one-dimensional (1D) interfaces. Although most attention has been focused on vertical HSs, increasing theoretical and experimental interest in 1D interfaces is evident. Read More

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http://dx.doi.org/10.1088/1361-648X/ab0970DOI Listing
February 2019

A comparison of exhaled breath online and offline measurements for diabetes pre-screening by graphene-based sensor: from powder processing to clinical monitoring prototype.

J Breath Res 2019 Feb 22. Epub 2019 Feb 22.

SRM University, Kattankulathur, Tamil Nadu, INDIA.

Several breath analysis studies have suggested a correlation between blood glucose (BG) levels and breath acetone, indicating acetone as a primary biomarker in exhaled breath for diabetes diagnosis. Herein, we have (i) fabricated and validated graphene based chemi-resistive sensors for selective and sensitive detection of acetone, (ii) performed offline breath analysis by static gas sensing setup to acquire olfactory signal and (iii) developed an LED based portable on/off binary e-nose system for pre-screening diabetes through online analysis. The fabricated sensors showed selective detection for acetone with high sensitivity (5. Read More

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http://dx.doi.org/10.1088/1752-7163/ab09aeDOI Listing
February 2019

Molecular beam epitaxial growth of dilute nitride GaNAs and GaInNAs nanowires.

Nanotechnology 2019 Feb 22. Epub 2019 Feb 22.

Ehime University Faculty of Engineering Graduate School of Science and Engineering, Matsuyama, Ehime, JAPAN.

We report the growth of dilute nitride GaNAs and GaInNAs core-multishell nanowires by plasma-assisted molecular beam epitaxy. Using constituent Ga-induced vapor-liquid-solid growth, these nanowires were grown on Si(111) and silicon on insulator (SOI) substrates. The GaNAs shell nominally contains 0%, 2%, and 3% nitrogen. Read More

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http://dx.doi.org/10.1088/1361-6528/ab0974DOI Listing
February 2019

Epidermal growth factor-nanoparticle conjugates change the activity from anti-apoptotic to pro-apoptotic at membrane rafts.

Acta Biomater 2019 Feb 19. Epub 2019 Feb 19.

WPI Research Initiative for Materials Nanoarchitectonics (MANA), National Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba, Ibaraki, 305-0044, Japan; Graduate School of Advanced Science and Engineering, Waseda University, 3-4-1 Okubo, Shinjuku-ku, Tokyo 169-8555, Japan. Electronic address:

The proliferation epidermal growth factor (EGF) is known to acquire contradictory apoptotic activities upon conjugation with gold nanoparticles (GNPs) through hitherto unknown mechanisms. Here, we identified an essential role of membrane rafts in the drastic activity switching of EGF-GNPs through the following intracellular signaling. 1) In contrast to the rapid diffusion of activated EGF receptor after the soluble EGF stimulation, the receptor is confined within membrane rafts upon binding to the EGF-GNPs. Read More

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http://dx.doi.org/10.1016/j.actbio.2019.02.026DOI Listing
February 2019

A transferrin receptor-binding mucoadhesive elastin-like recombinamer: in vitro and in vivo characterization.

Acta Biomater 2019 Feb 19. Epub 2019 Feb 19.

BIOFORGE (Group for Advanced Materials and Nanobiotechnology), CIBER-BBN, University of Valladolid, Paseo de Belén 19, 47011, Spain. Electronic address:

The development of mucoadhesive materials is of great interest and is also a major challenge. Being adsorption sites, mucosae are suitable targets for drug delivery, but as defensive barriers they are complex biological surfaces to interact with, mainly due to their protective mucus layer. As such, first- and second-generation mucoadhesives focused on material-mucus interactions, whereas the third generation of mucoadhesives introduced structural motifs that are able to interact with the cells beneath the mucus layer. Read More

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http://dx.doi.org/10.1016/j.actbio.2019.02.027DOI Listing
February 2019

Toward Tissue-engineering of Nasal Cartilages.

Acta Biomater 2019 Feb 19. Epub 2019 Feb 19.

Department of Biomedical Engineering, University of California Irvine, 3120 Natural Sciences II, Irvine, CA, 92697-2715, USA. Electronic address:

Nasal cartilage pathologies are common; for example, up to 80% of people are afflicted by deviated nasal septum conditions. Because cartilage provides the supportive framework of the nose, afflicted patients suffer low quality of life. To correct pathologies, graft cartilage is often required. Read More

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http://dx.doi.org/10.1016/j.actbio.2019.02.025DOI Listing
February 2019

Effect of magnesium-degradation products and hypoxia on the angiogenesis of human umbilical vein endothelial cells.

Acta Biomater 2019 Feb 19. Epub 2019 Feb 19.

Institute of Materials Research, Division for Metallic Biomaterials, Helmholtz-Zentrum Geesthacht (HZG), Geesthacht, Germany. Electronic address:

Biodegradable magnesium (Mg) metals have been applied in orthopaedic and stent applications due to their biodegradability, bioabsorbability and adaptability to tissue regeneration. However, further investigations are still needed to understand how angiogenesis will respond to high concentrations of Mg and oxygen content differences, which are vital to vascular remodelling and bone fracture regeneration or tissue healing. Human primary endothelial cells were exposed to various concentrations (2 to 8 mM) of extracellular Mg degradation products under either hypoxia or normoxia. Read More

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http://dx.doi.org/10.1016/j.actbio.2019.02.018DOI Listing
February 2019

VarGrouper - a Bioinformatic Tool for Local Haplotyping of Deletion-Insertion Variants from Next-generation Sequencing Data Post Variant Calling.

J Mol Diagn 2019 Feb 19. Epub 2019 Feb 19.

Department of Pathology, Harvard Medical School / Massachusetts General Hospital, Boston, Massachusetts. Electronic address:

Accurate genetic variant representation through nomenclature and annotation is essential for understanding functional consequence and properly noting the presence of variants across time, assays, and laboratories. Current variant calling algorithms detect single deletion-insertion variants as multiple indel and/or substitution variants from next-generation sequencing data. Consequently, these variants are separately annotated in bioinformatics pipelines, leading to inaccurate variant representation. Read More

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http://dx.doi.org/10.1016/j.jmoldx.2018.12.003DOI Listing
February 2019

Analytical Validation of Variants to Aid in Genotype-Guided Therapy for Oncology.

J Mol Diagn 2019 Feb 19. Epub 2019 Feb 19.

Department of Medicine, Division of Clinical Pharmacology.

The Clinical Laboratory Improvement Amendments (CLIA) of 1988 requires that pharmacogenetic genotyping methods need to be established according to technical standards and laboratory practice guidelines before testing can be offered to patients. Testing methods for variants in ABCB1, CBR3, COMT, CYP3A7, C8ORF34, FCGR2A, FCGR3A, HAS3, NT5C2, NUDT15, SBF2, SEMA3C, SLC16A5, SLC28A3, SOD2, TLR4, and TPMT were validated in a CLIA-accredited laboratory. As no known reference materials were available, DNA samples that were from Coriell Cell Repositories (Camden, NJ) were used for the analytical validation studies. Read More

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http://dx.doi.org/10.1016/j.jmoldx.2019.01.009DOI Listing
February 2019
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