7,098 results match your criteria Journal of Hospital Infection[Journal]


Antimicrobial-resistant Gram-negative colonisation in infants from a NICU in Thailand.

J Hosp Infect 2019 Apr 14. Epub 2019 Apr 14.

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.

Antimicrobial-resistant Gram-negative bacteria are a major cause of morbidity and mortality in hospitalised neonates in South and South-East Asia. We aimed to determine the dynamics of colonisation with antimicrobial-resistant Gram-negative bacteria amongst infants in a neonatal intensive care unit (NICU) in Thailand. From a total of 97 enrolled infants, 52% of neonates were colonised by an extended-spectrum β-lactamase (ESBL) organism at some point during their stay and 64% were colonised by a carbapenem-resistant organism. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01956701193015
Publisher Site
http://dx.doi.org/10.1016/j.jhin.2019.04.004DOI Listing
April 2019
1 Read

'The method used to dry washed hands affects the number and type of transient and residential bacteria remaining on the skin'.

J Hosp Infect 2019 Apr 13. Epub 2019 Apr 13.

Biomedical Sciences, University of Westminster, London, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.04.006DOI Listing
April 2019
2 Reads

Predictors of Mortality and Length of Stay in Patients with Hospital-Acquired Clostridioides difficile Infection: A Population-Based Study in Alberta, Canada.

J Hosp Infect 2019 Apr 13. Epub 2019 Apr 13.

Department of Community Health Sciences, University of Calgary, Calgary, Canada; Department of Medicine, University of Calgary, Calgary, Canada; O'Brien Institute for Public Health, University of Calgary and Alberta Health Services; Libin Cardiovascular Institute, University of Calgary, Calgary, Canada. Electronic address:

In a population-based, 5-year retrospective cohort study of 5304 adult patients with hospital-acquired Clostridioides difficile infection across Alberta (n=101 hospitals), 30-day all-cause and attributable mortality were 12.2% and 4.5%, respectively. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.04.007DOI Listing

Analysis of Acinetobacter baumannii survival in liquid media and on solid matrixes as well as effect of disinfectants.

J Hosp Infect 2019 Apr 12. Epub 2019 Apr 12.

Department of Immunology, Microbiology and Parasitology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU) Leioa, Spain; Research Centre for Experimental Marine Biology and Biotechnology (PIE-UPV/EHU), Plentzia, Spain.

Background: While being a cause of healthcare-associated infections, Acinetobacter baumannii possesses considerable potential to survive on inanimate hospital surfaces under hostile conditions (e.g. disinfection or desiccation). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.04.009DOI Listing

Comparative activity of a polyhexanide-betaine solution against biofilms produced by multidrug-resistant bacteria belonging to high-risk clones.

J Hosp Infect 2019 Apr 12. Epub 2019 Apr 12.

Unidad de Enfermedades Infecciosas, Microbiología y Medicina Preventiva, Hospital Universitario Virgen Macarena, Sevilla, Spain; Instituto de Biomedicina de Sevilla IBIS, Hospital Universitario Virgen Macarena/CSIC/Universidad de Sevilla, Sevilla, Spain; Red Española de Investigación en Patología Infecciosa (REIPI RD16/0016), Instituto de Salud Carlos III, Madrid, Spain; Departamento de Microbiología, Universidad de Sevilla, Sevilla, Spain.

The aim of this study was to investigate the effect of polyhexanide (polyhexamethylene biguanide)-betaine (PHMB-B) compared with 2% chlorhexidine against biofilms of high-risk and/or multidrug-resistant bacterial clones. The minimum inhibitory concentrations of both biocides were determined by microdilution. The effect of PHMB-B and chlorhexidine on biofilm was evaluated by spectrophotometry and cell viability assays. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.04.008DOI Listing

Age Alone is Not a Risk Factor for Periprosthetic Joint Infection.

J Hosp Infect 2019 Apr 10. Epub 2019 Apr 10.

Rothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, Pennsylvania. Electronic address:

Background: It is not known whether age alone or the increased comorbidities in the older patients are responsible for the higher rate of periprosthetic joint infection (PJI) in the older patients. The hypothesis of this study was that age alone is not a risk factor for PJI after total joint arthroplasty.

Methods: This retrospective study includes the review of 23,966 patients undergoing primary total hip and knee arthroplasty between January 1, 2010 and December 31, 2016 at a single institution. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.04.005DOI Listing

The Open Air Factor, and Infection Control.

Authors:
R A Hobday

J Hosp Infect 2019 Apr 9. Epub 2019 Apr 9.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01956701193015
Publisher Site
http://dx.doi.org/10.1016/j.jhin.2019.04.003DOI Listing
April 2019
1 Read

Oxygenating the argument for consistent performance of anaerobic blood cultures and blood volumes collected.

J Hosp Infect 2019 Apr 8. Epub 2019 Apr 8.

Graduate Entry Medical School, University of Limerick, Limerick, V94 T9PX, Ireland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.04.002DOI Listing

First evidence of KPC-producing ST258 Klebsiella pneumoniae in river water.

J Hosp Infect 2019 Apr 5. Epub 2019 Apr 5.

Department of Clinical Microbiology, University Hospital for Infectious Diseases, Zagreb, Croatia; University of Zagreb Dental School, Zagreb, Croatia.

We report the first occurrence of KPC-2-producing Klebsiella pneumoniae in river water, in Croatia. In total, four KPC-2-producing K. pneumoniae isolates were analysed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.04.001DOI Listing

Do we need to remove rapidly central venous catheter to treat Staphylococcus aureus related-catheter bloodstream infection (CR-BSI) in neonates and children? A 8-year period (2010-2017) retrospective analysis in a French University Hospital.

J Hosp Infect 2019 Apr 4. Epub 2019 Apr 4.

MiHAR Lab, University of Nantes, Nantes, FR-44000; Bacteriology and Infection Control Department, Nantes University Hospital, Nantes, FR-44000. Electronic address:

Catheter-relate bloodstream infection (CR-BSI) treatment is based on empiric antibiotherapy associated with or without catheter removal. The aim of this study was to compare the incidence of failures in neonates and children with S. aureus CR-BSI with or without rapid catheter removal. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.03.015DOI Listing
April 2019
1 Read

Bacterial load and pathogenic species on healthcare personnel attire: implications of alcohol hand-rub use, profession, and time of duty.

J Hosp Infect 2019 Apr 26;101(4):414-421. Epub 2018 Oct 26.

Biostatistics, Helmholtz Centre for Infection Research, Braunschweig, Germany.

Background: Since hand hygiene might prevent the risk of bacterial transmission from healthcare personnel attire (HCPA), the present study investigates the effect of alcohol-based hand rub (ABHR) use on bacterial load and pathogenic species on HCPA.

Methods: HCPA from doctors and nurses was investigated for bacterial contamination post duty. Samples from distinct areas of HCPA were obtained and analysed for bacterial load and species. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2018.10.017DOI Listing
April 2019
1 Read

Improving healthcare worker adherence to the use of transmission-based precautions through application of human factors design: a prospective multi-centre study.

J Hosp Infect 2019 Mar 29. Epub 2019 Mar 29.

Infection Prevention and Control, Michael Garron Hospital, Toronto, Ontario, Canada. Electronic address:

A key component of transmission-based precautions (TBPs) is the use of personal protective equipment (PPE) but healthcare worker (HCW) adherence remains suboptimal. A human factors-based intervention was implemented to improve adherence to TBPs including (i) improved signage, (ii) standardized placement of signage, (iii) introduction of a mask with integrated face shield, and (iv) improvement in PPE availability. Donning of the correct PPE by HCWs improved significantly (79. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01956701193014
Publisher Site
http://dx.doi.org/10.1016/j.jhin.2019.03.014DOI Listing
March 2019
2 Reads

Interventions to improve hand hygiene compliance in emergency departments: A systematic review.

J Hosp Infect 2019 Mar 29. Epub 2019 Mar 29.

College of Nursing, The Catholic University of Korea, Seoul, Korea. Electronic address:

Background: The emergency department (ED) is where hand hygiene problems are significant as the procedures in the ED are often high risk and invasive. To date, there have been no comprehensive reviews on hand hygiene in EDs.

Aim: To investigate hand hygiene compliance (HHC) rate, factors affecting the HHC rate, and intervention strategies to improve HHC in EDs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.03.013DOI Listing

A Model to Evaluate the Impact of Hospital-Based Interventions Targeting False-positive Blood Cultures on Economic and Clinical Outcomes.

J Hosp Infect 2019 Mar 27. Epub 2019 Mar 27.

From Wing Tech Inc, Menlo Park, CA. Electronic address:

Background: Blood culture contamination (BCC) increases length of stay (LOS) and leads to unnecessary anti-microbial therapy and/or hospital-acquired conditions (HACs).

Aim: We sought to quantify the magnitude of the additional LOS, costs to hospitals and society as well as the harm to patients attributable to BCC.

Methods: A retrospective matched survival analysis was performed involving hospitalized patients with septicaemia-compatible symptoms. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.03.012DOI Listing
March 2019
1 Read
2.544 Impact Factor

Faecal microbiota transplantation for the decolonisation of antibiotic-resistant bacteria in the gut: a systematic review and meta-analysis.

Authors:
Vera Tavoukjian

J Hosp Infect 2019 Mar 26. Epub 2019 Mar 26.

Florence Nightingale Faculty of Nursing, Midwifery and Palliative Care, King's College London, James Clerk Maxwell Building, 57 Waterloo Road, London SE1 8WA, United Kingdom. Electronic address:

Background: Antibiotic resistance is a growing global problem associated with increased morbidity and mortality, and presents a significant financial and economic burden on healthcare. FMT has been proven effective for curing recurrent Clostridium difficile infections, however no systematic review to date has addressed its effectiveness for decolonisation of antibiotic-resistant bacteria from the gut.

Aim: To answer the following research question: Does faecal microbiota transplantation decolonise antibiotic-resistant bacteria from the gut of colonised adults?

Methods: A systematic review was performed by undertaking a comprehensive search on MEDLINE, Embase, CENTRAL, PubMed and CINAHL databases for evidence up till May 2018. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.03.010DOI Listing

Design variables with significant effect on system performance of unidirectional displacement airflow systems in hospitals.

J Hosp Infect 2019 Mar 25. Epub 2019 Mar 25.

The Netherlands Organisation for Applied Scientific Research TNO, Delft, the Netherlands.

Background: The effectiveness of an airflow system in preventing entrainment of particles carrying micro-organisms from the periphery of an operating room (OR) or instrument lay-up room (ILR) is affected by many variables. It is suspected that differences in the design of the systems affect the effective protection ratio (EPR): the ratio of the size of the protected area to the surface area of the supply canopy. However, no analysis has yet been done to determine which design variables have a significant effect on this ratio. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.03.009DOI Listing
March 2019
4 Reads

Prevalence of healthcare-associated infections and antimicrobial resistance in Kyiv acute care hospitals, Ukraine.

J Hosp Infect 2019 Mar 22. Epub 2019 Mar 22.

The Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine.

Background: Healthcare-associated infections (HAIs) are one of the commonest adverse events in patient care and account for substantial morbidity and mortality.

Aim: To obtain the first estimates of the current prevalence of HAIs and antimicrobial resistance in acute care hospitals in Kyiv, Ukraine.

Methods: Prospective surveillance was conducted from January 2014 to December 2016 in five Kyiv acute care hospitals. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.03.008DOI Listing
March 2019
1 Read

Detection of antibiotic resistance genes from blood cultures: performance assessment and potential impact on antibiotic therapy management.

J Hosp Infect 2019 Mar 21. Epub 2019 Mar 21.

Microbiology and Virology Unit, University Hospital Città della Salute e della Scienza di Torino, Turin, Italy.

Molecular assays may constitute a valid method to timely predict antimicrobial resistance and optimize empirical antibiotic therapies. We assessed ELITe MGB assays in blood culture workflow to detect main carbapenemase and ESBL genes, Staphylococcus aureus and mec genes in less than 3h. Excellent agreement results between genotypic and conventional phenotypic approaches were obtained. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.03.007DOI Listing

Hepatitis B and C among healthcare workers and patient groups at increased risk of iatrogenic transmission in the European Union/European Economic Area.

J Hosp Infect 2019 Mar 15. Epub 2019 Mar 15.

European Centre for Disease Prevention and Control, Stockholm, Sweden.

In the European Union/European Economic Area (EU/EEA) approximately 9 million people are chronically infected with hepatitis B virus (HBV) or hepatitis C virus (HCV), and many are undiagnosed. Targeted active case finding initiatives are needed. Iatrogenic transmission of HBV/HCV is relevant in Europe but people at risk of infection are often overlooked. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.03.004DOI Listing
March 2019
1 Read

Laboratory exposure to Coccidioides: lessons learnt in a non-endemic country.

J Hosp Infect 2019 Mar 16. Epub 2019 Mar 16.

Laboratorio Clínico, Clínica Alemana de Santiago, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, Santiago, Chile; Programa Medicina del Viajero, Clínica Alemana de Santiago, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, Santiago, Chile.

Coccidioides is a primary pathogenic fungus, which infects humans through highly infectious arthroconidia, causing substantial morbidity including life-threatening disseminated infections. Due to the low infectious dose, laboratory personnel might become infected during diagnostic procedures. Accordingly, coccidioidomycosis is reported as the most frequent laboratory-acquired systemic mycosis worldwide. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.03.006DOI Listing
March 2019
1 Read

Can the resistance profile affect the survival of Acinetobacter baumannii on hospital surfaces?

J Hosp Infect 2019 Mar 16. Epub 2019 Mar 16.

Laboratório de Microbiologia, Departamento de Ciências Básicas da Saúde, Universidade Estadual de Maringá, Maringá, Paraná, Brazil. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.03.005DOI Listing

Seasonality and community interventions in a mathematical model of Clostridium difficile transmission.

J Hosp Infect 2019 Mar 15. Epub 2019 Mar 15.

Research School of Population Health, Australian National University, Canberra, Australian Capital Territory, Australia.

Background: Clostridium difficile infection (CDI) is the leading cause of antibiotic-associated diarrhoea with peak incidence in late winter or early autumn. Although CDI is commonly associated with hospitals, community transmission is important.

Aim: To explore potential drivers of CDI seasonality and the effect of community-based interventions to reduce transmission. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.03.001DOI Listing

Reply to: Concerns regarding the validity of the conclusion in a recently published paper on Roche Liat implementation.

J Hosp Infect 2019 Mar 14. Epub 2019 Mar 14.

Infection Care Group, St George's University Hospitals NHS Foundation Trust, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.03.003DOI Listing

The economic impact of antimicrobial stewardship programmes in hospitals: a systematic literature review.

J Hosp Infect 2019 Mar 14. Epub 2019 Mar 14.

University of Greifswald, Chair of Health Care Management, Greifswald, Germany.

Background: Antimicrobial stewardship programmes (ASPs) include strategies that enable sustainable management of rational anti-infective treatment in the clinical setting. The successful introduction of ASPs requires close interdisciplinary collaboration among various health professionals, including the hospital management. So far, ASPs have been evaluated mainly from a clinical-pharmacological and infectious disease perspective. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.03.002DOI Listing

Emergence of Candida auris in Russia.

J Hosp Infect 2019 Mar 6. Epub 2019 Mar 6.

Almazov National Medical Research Centre, Saint-Petersburg, Russia. Electronic address:

This paper reports the emergence of Candida auris infections in an intensive care unit at a hospital in Moscow. Forty-nine cases were diagnosed in 2016-2017, and the risk factors and antifungal susceptibilities are described. The 30-day all-cause mortality for 19 bloodstream infections in patients who did not receive appropriate antifungal therapy was 42. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.02.021DOI Listing
March 2019
20 Reads

'Clean care for all - it's in your hands': the 5 May 2019 World Health Organization SAVE LIVES: Clean Your Hands campaign.

J Hosp Infect 2019 Mar 1. Epub 2019 Mar 1.

Infection Control Programme and WHO Collaborating Centre on Patient Safety, University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.02.020DOI Listing
March 2019
1 Read

Healthcare workers' attitudes towards hand-hygiene monitoring technology.

J Hosp Infect 2019 Mar 2. Epub 2019 Mar 2.

Aix Marseille University, IRD, AP-HM, SSA, VITROME, IHU-Méditerranée Infection, Marseille, France. Electronic address:

Background: Automated radio-frequency identification (RFID)-based hand-hygiene monitoring technology was implemented in an infectious disease department to study healthcare workers' (HCWs') practices and to improve hand hygiene.

Aim: To assess HCWs' attitudes towards this innovative monitoring device in order to anticipate resistance to change and facilitate future implementation.

Methods: In-depth interviews and an ethnographic approach. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.02.017DOI Listing
March 2019
7 Reads

Tackling antimicrobial resistance 2019-2024 - The UK's five-year national action plan.

J Hosp Infect 2019 Apr 1;101(4):426-427. Epub 2019 Mar 1.

School of Healthcare Sciences, Cardiff University, Cardiff, UK; Hywel Dda University Health Board, Carmarthen, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.02.019DOI Listing

Lessons learned from a Pneumocystis Pneumonia outbreak at a Scottish renal transplant centre.

J Hosp Infect 2019 Feb 22. Epub 2019 Feb 22.

NHS Lothian Infection Service, Clinical Microbiology, Royal Infirmary of Edinburgh, Edinburgh EH16 4SA UK. Electronic address:

Background: Pneumocystis Pneumonia (PCP) is an opportunistic infection occurring in renal transplant patients. Over a 14 month period an increase in PCP cases was identified amongst our renal transplant cohort.

Aim: The outbreak population was studied to identify potential risk factors for the development of PCP. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.02.013DOI Listing
February 2019
1 Read

Concerns regarding the validity of the conclusion in a recently published paper on Roche Liat implementation.

J Hosp Infect 2019 Feb 23. Epub 2019 Feb 23.

Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.02.011DOI Listing
February 2019

In-vitro antibacterial and anti-encrustation performance of silver-polytetrafluoroethylene nanocomposite coated urinary catheters.

J Hosp Infect 2019 Feb 22. Epub 2019 Feb 22.

School of Science and Engineering, University of Dundee, Dundee, UK. Electronic address:

Background: Catheter-associated urinary tract infections (CAUTIs) are among the most common hospital-acquired infections, leading to increased morbidity and mortality. A major reason for this is that urinary catheters are not yet capable of preventing CAUTIs.

Aim: To develop an anti-infective urinary catheter. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.02.012DOI Listing
February 2019

Transmission of multi-drug resistant Pseudomonas aeruginosa between two flexible ureteroscopes and an outbreak of urinary tract infection: the fragility of endoscope decontamination.

J Hosp Infect 2019 Feb 22. Epub 2019 Feb 22.

Department of Microbiology, Kings College Hospital NHS Foundation Trust, Denmark Hill, London SE5 9RS, UK. Electronic address:

Objectives: Flexible endoscopes are difficult to decontaminate, and endoscope-associated infections are increasing. This report describes an outbreak of multi-drug resistant Pseudomonas aeruginosa identified following an increase in incidence of clinical infections associated with flexible ureteroscopy at a tertiary care centre in the UK.

Methods: Clinical, laboratory and central decontamination unit (CDU) records were reviewed to determine the extent of the problem, and links to the used endoscopes. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01956701193009
Publisher Site
http://dx.doi.org/10.1016/j.jhin.2019.02.015DOI Listing
February 2019
10 Reads

Factors affecting bacterial load on nurses' white coats.

J Hosp Infect 2019 Feb 22. Epub 2019 Feb 22.

Department of Textile Technology, Indian Institute of Technology Delhi, Hauz Khas, New Delhi, India. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.02.014DOI Listing
February 2019
2.544 Impact Factor

Prevention of deep sternal wound infections in cardiac surgery - reply to Vos et al.

J Hosp Infect 2019 Feb 23. Epub 2019 Feb 23.

University of Huddersfield, Huddersfield, UK.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01956701193009
Publisher Site
http://dx.doi.org/10.1016/j.jhin.2019.02.016DOI Listing
February 2019
3 Reads

Potential distribution of viable norovirus after simulated vomiting.

J Hosp Infect 2019 Feb 21. Epub 2019 Feb 21.

Health and Safety Executive, Buxton, UK.

Background: Vomiting is one way in which the body rids itself of harmful gastric contents rapidly. Whilst this process is generally beneficial for the emetic individual, it can pose significant infection control issues if they are infected with a highly communicable pathogen such as norovirus. It is not known how far norovirus could spread through vomiting while remaining viable, particularly in far-reaching droplets and splashes that might be missed during cleaning. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.02.010DOI Listing
February 2019
1 Read

Instrument cleanliness and protein misfolding disorders.

Authors:
R L Salmon

J Hosp Infect 2019 Feb 20. Epub 2019 Feb 20.

Chair Advisory Committee on Dangerous Pathogens, Transmissible Spongiform Encephalopathy Subgroup, c/o Public Health England, 61 Colindale Avenue, London NW9 5EQ, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.02.009DOI Listing
February 2019

Effectiveness and core components of infection prevention and control programmes in long-term care facilities: a systematic review.

J Hosp Infect 2019 Feb 19. Epub 2019 Feb 19.

The Research Institute of Nursing Science, College of Nursing, Seoul National University, Seoul, Republic of Korea. Electronic address:

Background: Infection prevention and control (IPC) is a measure to prevent healthcare-associated infections in healthcare settings. There is limited evidence of the effectiveness of IPC programmes in long-term care facilities (LTCFs).

Aim: To review and analyse the effectiveness and the components of IPC programmes in LTCFs for older adults. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.02.008DOI Listing
February 2019
1 Read

Prolonged norovirus shedding and the use of a rapid norovirus polymerase chain reaction to assess terminal room cleaning in immunocompromised patients.

J Hosp Infect 2019 Feb 19. Epub 2019 Feb 19.

University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital Birmingham, Edgbaston, Birmingham, UK; Institute of Microbiology and Infection, The University of Birmingham, Edgbaston, Birmingham, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.02.006DOI Listing
February 2019
1 Read

Healthcare-associated infections and antimicrobial use in long-term care facilities (HALT3): an overview of the Italian situation.

J Hosp Infect 2019 Feb 19. Epub 2019 Feb 19.

Department of Public Health and Paediatrics, University of Turin, Turin, Italy.

Background: Awareness of healthcare-associated infections (HAIs) and antimicrobial use in long-term care facilities (LTCFs) is increasing. In 2017, the third national point prevalence survey (PPS) was conducted in Italy as part of the third 'Healthcare-Associated Infections in European Long-Term Care Facilities' (HALT3) study.

Aim: To report the results of HALT3 and analyse the resident population of LTCFs, implementation of good practices, prevalence of infections and antimicrobial use. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.02.007DOI Listing
February 2019
2 Reads

Bacterial contamination rate and associated factors during bone and tendon allograft procurement from Spanish donors: exploring the contamination patterns.

J Hosp Infect 2019 Feb 14. Epub 2019 Feb 14.

Transplant Coordination Department, Hospital Clínico San Carlos, Madrid, Spain; Health Research Institute, Hospital Clínico San Carlos, Madrid, Spain.

Background: Allograft contamination during extraction represents a major limiting factor for tissue bank availability. Contamination rates remain persistently high independent of the hospital, country or year considered.

Aim: To analyse the factors associated with contamination of bone and tendon samples extracted from Spanish donors. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.02.005DOI Listing
February 2019
1 Read

Results of a multi-faceted educational intervention to prevent peripheral venous catheter-associated bloodstream infections.

J Hosp Infect 2019 Feb 13. Epub 2019 Feb 13.

Infectious Diseases Unit/Internal Medicine Department, Hospital Son Llátzer, Palma de Mallorca, Baleares, Spain.

Peripheral venous catheter-associated bloodstream infections (PVC-BSIs) lead to prolonged hospitalization, morbidity and increased costs. The impact of infection-prevention measures on the rate of PVC-BSIs in a university hospital in Spain was assessed. An active surveillance programme was initiated in 2015, which revealed a high PVC-BSI incidence ratio (0. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.02.004DOI Listing
February 2019

Evaluation of an 'all-in-one' seven-day whole-genome sequencing solution in the investigation of a Staphylococcus aureus outbreak in a neonatal intensive care unit.

J Hosp Infect 2019 Feb 14. Epub 2019 Feb 14.

AP-HP, Hôpitaux Universitaires Paris Sud, Hôpital Antoine Béclère, Service de Bactériologie-Hygiène, Clamart, France; EA4043, Bactéries pathogènes et santé, Faculté de Pharmacie, Université Paris Sud, Chatenay-Malabry, France; Institute of Integrative Biology of the Cell, CNRS, CEA, Université Paris Sud, Paris Saclay University, Gif sur Yvette, France. Electronic address:

Background: Meticillin-susceptible and -resistant Staphylococcus aureus (MSSA and MRSA) are responsible for outbreaks in intensive care units. MSSA infections have the same morbidity and mortality rate as MRSA infections but are studied less often. Whole-genome sequencing (WGS) is used increasingly for outbreak monitoring, but still requires specific installation and trained personnel to obtain and analyse the data. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.01.029DOI Listing
February 2019
4 Reads

Psychometric evaluation of a measure of factors influencing hand hygiene behaviour to inform intervention.

J Hosp Infect 2019 Feb 13. Epub 2019 Feb 13.

Irish Centre for Applied Patient Safety and Simulation, School of Medicine, National University of Ireland Galway, Ireland; Discipline of General Practice, School of Medicine, National University of Ireland Galway, Ireland. Electronic address:

Background: Although the hand hygiene (HH) procedure is simple, the related behaviour is complex and is not readily understood, explained or changed. There is a need for practical tools to provide data that can guide healthcare managers and practitioners not only on the 'what' (the standards that must be met), but also the 'how' (guidance on how to achieve the standards).

Aim: To develop a valid questionnaire to evaluate attitudes to the factors that influence engagement in HH behaviour that can be readily completed, administered and analysed by healthcare professionals to identify appropriate intervention strategies. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.02.003DOI Listing
February 2019
1 Read

Carbapenemase-producing Enterobacteriaceae digestive carriage at hospital readmission and the role of antibiotic exposure.

J Hosp Infect 2019 Feb 12. Epub 2019 Feb 12.

Microbiotas, Host, Antibiotics, Bacterial Resistance (MiHAR Lab), University of Nantes, Nantes, France; Bacteriology and Infection Control Department, Nantes University Hospital, Nantes, France. Electronic address:

Background: Colonization by carbapenemase-producing Enterobacteriaceae (CPE) may persist for several months after hospital discharge, especially in patients with altered microbiota.

Aim: To identify how many previously OXA-48 CPE-positive patients identified during an outbreak period were readmitted; to evaluate their CPE-positive or -negative digestive tract colonization at hospital readmission and during readmission stay; and to assess the role of antibiotic exposure on their CPE colonization status during readmission.

Methods: All CPE cohort patients from June 2013 to May 2016 (N = 189) were registered in a survey database and were systematically identified at readmission by a daily informatics and alert program using specific hospital population number. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.02.002DOI Listing
February 2019
1 Read

Down the drain and back up a drain.

Authors:
M Weinbren

J Hosp Infect 2019 Feb 8. Epub 2019 Feb 8.

King's Mill NHS Foundation Trust, Sutton-In-Ashfield, Nottinghamshire, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.01.027DOI Listing
February 2019
5 Reads

A quasi-randomized controlled before-after study using performance feedback and goal setting as elements of hand hygiene promotion.

J Hosp Infect 2019 Apr 8;101(4):399-407. Epub 2019 Feb 8.

Department of Social Psychology, Ulm University, Ulm, Germany.

Background: Hand hygiene (HH) plays an important role in infection prevention but is often suboptimal.

Aim: To test the potential of goal setting and performance feedback in improving HH.

Methods: A prospective controlled intervention study was conducted at a German hospital. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2019.02.001DOI Listing

A tsunami of drug resistance in Iran's hospitals, is it true?

J Hosp Infect 2019 Apr 6;101(4):480-481. Epub 2019 Feb 6.

Department of Microbiology, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhin.2018.12.021DOI Listing
April 2019
1 Read