7,056 results match your criteria Journal of Hospital Infection[Journal]


Bacterial contamination rate and associated factors during bone and tendon allograft procurement from Spanish donors.

J Hosp Infect 2019 Feb 14. Epub 2019 Feb 14.

Transplant Coordination Department, Hospital Clínico San Carlos, Madrid, Spain; Health Research Institute, Hospital Clínico San Carlos, Madrid, Spain.

Background: Allograft contamination during extraction represents a major limiting factor for tissue bank availability. Contamination rates remain persistently high independently of the hospital, country or year considered.

Aim: The present study analyses the factors associated with contamination of bone and tendon samples extracted from Spanish donors. Read More

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http://dx.doi.org/10.1016/j.jhin.2019.02.005DOI Listing
February 2019

Results of a multifaceted educational intervention to prevent peripheral venous catheter-associated bloodstream infections.

J Hosp Infect 2019 Feb 13. Epub 2019 Feb 13.

Infectious Diseases Unit/Internal Medicine Dept. Hospital Universitari Son Llàtzer. Crtra Manacor Km 4. 07198, Palma de Mallorca.Baleares. Spain. Electronic address:

Peripheral venous catheter-associated bloodstream infections (PVC-BSIs) lead to prolonged hospitalization, morbidity, and increased costs. We assessed the impact of infection prevention measures on the rate of PVC-BSIs in a university hospital in Spain. An active surveillance programme was initiated in 2015, which revealed a high PVC-BSI Incidence Ratio (0. Read More

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http://dx.doi.org/10.1016/j.jhin.2019.02.004DOI Listing
February 2019

Evaluation of an "all-in-one" seven-day WGS solution in the investigation of a Staphylococcus aureus outbreak in a neonatal Intensive Care Unit.

J Hosp Infect 2019 Feb 13. Epub 2019 Feb 13.

AP-HP, Hôpitaux Universitaires Paris Sud, Hôpital Antoine Béclère, Service de Bactériologie-Hygiène, Clamart, France; EA4043, Bactéries Pathogènes et Santé, Faculté de Pharmacie, Université Paris Sud, Chatenay-Malabry, France; Institute of Integrative Biology of the Cell, CNRS, CEA, Univ. Paris Sud, Paris Saclay University, Gif sur Yvette, France. Electronic address:

Background: Meticillin-susceptible and resistant Staphylococcus aureus (MSSA and MRSA) are responsible for outbreaks in intensive care units. MSSA infections have the same morbidity and mortality rate as MRSA infections but are less often studied. Whole genome sequencing (WGS) is increasingly used for outbreak monitoring but still requires specific installation and trained personnel to obtain and analyse the data. Read More

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http://dx.doi.org/10.1016/j.jhin.2019.01.029DOI Listing
February 2019
1 Read

Psychometric Evaluation of a Measure of Factors Influencing Hand Hygiene Behaviour to Inform Intervention.

J Hosp Infect 2019 Feb 12. Epub 2019 Feb 12.

Irish Centre for Applied Patient Safety and Simulation, School of Medicine, National University of Ireland Galway, Ireland; Discipline of General Practice, School of Medicine, National University of Ireland Galway, Ireland. Electronic address:

Background: Although the hand hygiene (HH) procedure is simple, the related behaviour is complex and is not readily understood, explained, or changed. There is a need for practical tools to provide data that can guide healthcare managers and practitioners not only on the 'what' (the standards that must be met), but also the 'how' (guidance on how to achieve the standards).

Aim: To develop a valid questionnaire to evaluate attitudes to the factors that influence engagement in HH behaviour that can be readily completed, administered, and analysed by healthcare professionals to identify appropriate intervention strategies. Read More

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http://dx.doi.org/10.1016/j.jhin.2019.02.003DOI Listing
February 2019

Carbapenemase-producing Enterobacteriaceae digestive carriage at hospital readmission and the role of antibiotic exposure.

J Hosp Infect 2019 Feb 12. Epub 2019 Feb 12.

Microbiotas, Host, Antibiotics, bacterial Resistance (MiHAR Lab), University of Nantes, Nantes, France; Bacteriology and Infection Control Department, Nantes University Hospital, Nantes, France. Electronic address:

Background: Colonization by carbapenemase-producing Enterobacteriaceae (CPE) may persist for several months after hospital discharge, especially in patients with altered microbiota.

Aim: To identify how many previously OXA-48 CPE-positive patients identified during an outbreak period were readmitted; to evaluate their CPE-positive or -negative digestive tract colonization at hospital readmission and during readmission stay; and to assess the role of antibiotic exposure on their CPE colonization status during readmission.

Methods: All CPE cohort patients from June 2013 to May 2016 (N = 189) were registered in a survey database and were systematically identified at readmission by a daily informatics and alert program using specific hospital population number. Read More

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http://dx.doi.org/10.1016/j.jhin.2019.02.002DOI Listing
February 2019

Down the drain and back up a drain.

Authors:
M Weinbren

J Hosp Infect 2019 Feb 8. Epub 2019 Feb 8.

King's Mill NHS Foundation Trust, Sutton-In-Ashfield, Nottinghamshire, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jhin.2019.01.027DOI Listing
February 2019

A quasi-randomized controlled before-after study using performance feedback and goal setting as elements of hand hygiene promotion.

J Hosp Infect 2019 Feb 7. Epub 2019 Feb 7.

Department of Social Psychology, Ulm University, Ulm Germany.

Background: Hand hygiene (HH) plays an important role in infection prevention but is often suboptimal.

Aim: To test the potential of goal setting and performance feedback in improving HH.

Method: A prospective controlled intervention study was conducted at a German hospital. Read More

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http://dx.doi.org/10.1016/j.jhin.2019.02.001DOI Listing
February 2019

A tsunami of drug resistance in Iran's hospitals, is it true?

J Hosp Infect 2019 Feb 5. Epub 2019 Feb 5.

Department of Microbiology, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.

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http://dx.doi.org/10.1016/j.jhin.2018.12.021DOI Listing
February 2019
1 Read

Response to the article 'Instrument cleanliness and protein misfolding disorders'.

Authors:
Michael Simmons

J Hosp Infect 2019 Feb 5. Epub 2019 Feb 5.

Public Health Wales, Carmarthen, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jhin.2019.01.028DOI Listing
February 2019

Ozonized water as an alternative to alcohol-based hand disinfection.

J Hosp Infect 2019 Feb 4. Epub 2019 Feb 4.

Faculty of Western Norway University of Applied Sciences, Førde, Norway.

Background: Hand hygiene plays a vital role in the prevention of transmission of microorganisms. Ozone (O3) is a highly reactive gas with a broad spectrum of antimicrobial effects on bacteria, viruses and protozoa. It can easily be produced locally in small generators, and dissolved in tap water, and quickly transmits into ordinary O2 in the surrounding air. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01956701193005
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http://dx.doi.org/10.1016/j.jhin.2019.01.026DOI Listing
February 2019
5 Reads

The contribution of whole-genome sequencing to our understanding of the epidemiology and control of methicillin-resistant Staphylococcus aureus.

J Hosp Infect 2019 Feb 2. Epub 2019 Feb 2.

Microbiology Research Unit, Dublin Dental University Hospital, Trinity College Dublin, University of Dublin, Dublin, Ireland.

In recent years, approaches to tracking the spread of meticillin-resistant Staphylococcus aureus (MRSA) as part of outbreak management have used conventional DNA-based methods including pulsed field gel electrophoresis (PFGE) and spa typing. However, when a predominant clone is present, these methods may be insufficiently discriminatory. We conducted a literature search to highlight how whole genome sequencing (WGS) has revolutionised the investigation of outbreaks of MRSA, including intra-hospital spread and MRSA in the community, and to review its future potential. Read More

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http://dx.doi.org/10.1016/j.jhin.2019.01.025DOI Listing
February 2019

The Clinical Risk Stratification and Antibiotic Management of NDM and OXA-48 carbapenemase-producing Enterobacteriaceae bloodstream infections the United Kingdom.

J Hosp Infect 2019 Feb 1. Epub 2019 Feb 1.

National Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London, Hammersmith Campus, Du Cane Road, London, W12 0NN, UK; Hammersmith Hospital, Imperial College Healthcare NHS Trust, Du Cane Road, London W12 0HS UK.

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http://dx.doi.org/10.1016/j.jhin.2019.01.023DOI Listing
February 2019

Prospective surveillance of bacterial colonization and primary sepsis - findings of a tertiary neonatal intensive and intermediate care unit.

J Hosp Infect 2019 Feb 1. Epub 2019 Feb 1.

Institute for Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany. Electronic address:

Background: Preterm infants and critically ill neonates are predisposed to nosocomial infections as sepsis. Moreover, these infants acquire commensal bacteria, which might become potentially harming. On-ward transmission of these bacteria can cause outbreaks. Read More

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http://dx.doi.org/10.1016/j.jhin.2019.01.021DOI Listing
February 2019
1 Read

Corrigendum to "Environmental contamination by bacteria in hospital washrooms according to hand-drying method: a multi-centre study" [J Hospital Infection 100 (2018) 469-475].

J Hosp Infect 2019 Jan 31. Epub 2019 Jan 31.

Microbiology, Leeds Teaching Hospitals, Leeds, UK; University of Leeds, Leeds, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jhin.2019.01.014DOI Listing
January 2019

60% and 70% isopropanol are effective against "isopropanol-tolerant" E. faecium.

J Hosp Infect 2019 Jan 31. Epub 2019 Jan 31.

Institute for Hygiene and Public Health, University Hospital Bonn, Sigmund-Freud-Str. 25, 53127 Bonn, Germany.

We have determined the bactericidal activity of isopropanol against E. faecium ATCC 6057, ST 796 (isopropanol-tolerant strain) and E. hirae ATCC 10541 (EN 13727). Read More

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http://dx.doi.org/10.1016/j.jhin.2019.01.024DOI Listing
January 2019

Incidence of methicillin-resistant Staphylococcus aureus contamination on mobile phones of medical students.

Authors:
Z N L Goh P Y Chung

J Hosp Infect 2019 Jan 31. Epub 2019 Jan 31.

School of Medicine, International Medical University, Kuala Lumpur, Malaysia. Electronic address:

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http://dx.doi.org/10.1016/j.jhin.2019.01.022DOI Listing
January 2019
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The Burden of Clostridium difficile Infection During Inpatient Stays in the United States between 2012 and 2016.

J Hosp Infect 2019 Jan 25. Epub 2019 Jan 25.

Da Volterra, 172 Rue de Charonne, Paris, France. Electronic address:

Background: The healthcare burden of Clostridium (Clostridioides) difficile infection (CDI) is high but not fully characterized.

Aim: The objective of this study was to assess hospitalization costs, length of hospital stay (LOS), and in-hospital mortality attributable to CDI in the United States by analysing nationwide hospital discharge records over the 2012-2016 period.

Methods: A retrospective, observational study based on the Truven Health MarketScan Hospital Drug Database was conducted, in which 46 097 inpatient stays with a diagnosis of CDI were analyzed. Read More

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http://dx.doi.org/10.1016/j.jhin.2019.01.020DOI Listing
January 2019

Hospital Acquired Clostridium difficile Infection (HA-CDI): An institutional costing analysis.

J Hosp Infect 2019 Jan 25. Epub 2019 Jan 25.

School of Epidemiology, Public Health and Preventive Medicine, University of Ottawa, Canada; Department of Medicine, The Ottawa Hospital and University of Ottawa, Ottawa, Ontario, Canada; Ottawa Hospital Research Institute, Ottawa, Ontario, Canada. Electronic address:

Background: Healthcare-acquired Clostridium difficile infection (HA-CDI) is a common infection and a financial burden on the healthcare system.

Aim: To estimate the hospital-based financial costs of HA-CDI by comparing time-fixed statistical models that attribute cost to the entire hospital stay to time-varying statistical models that adjust for the time between admission, diagnosis of HA-CDI, and discharge and only attribute HA-CDI costs post diagnosis.

Methods: A retrospective cohort study was conducted (April 2008-March 2011) using clinical and administrative costing data of inpatients (≥15 years) who were admitted to The Ottawa Hospital with stays > 72h. Read More

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http://dx.doi.org/10.1016/j.jhin.2019.01.019DOI Listing
January 2019

Development of case vignettes for assessment of the inter-rater variability of national validation teams for the Point Prevalence Survey of Healthcare-Associated Infections and Antimicrobial Use in European Acute Care Hospitals.

J Hosp Infect 2019 Jan 22. Epub 2019 Jan 22.

European Centre for Disease Prevention and Control, Solna, Sweden.

Background: In 2016-17 ECDC organised the second Point Prevalence Survey (PPS) of healthcare-associated infections (HAIs) and antimicrobial use in European acute care hospitals. This survey included a validation study to maximise the accuracy of case identification and classification.

Aim: ECDC developed case vignettes to assess the performance of the national validation teams. Read More

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http://dx.doi.org/10.1016/j.jhin.2019.01.018DOI Listing
January 2019
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Candidemia in an Irish intensive care unit (ICU) setting between 2004 and 2018 reflects increased incidence of Candida glabrata.

J Hosp Infect 2019 Jan 19. Epub 2019 Jan 19.

Centre for Interventions in Infection, Inflammation & Immunity (4i) and Graduate Entry Medical School, University of Limerick, Limerick, Ireland. Electronic address:

The cumulative incidence of candidemia in an Irish Intensive Care Unit (ICU) setting between January 2004 and August 2018 was 17/1000 ICU admissions. Candida albicans was responsible for 55% (n=41). C. Read More

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http://dx.doi.org/10.1016/j.jhin.2019.01.017DOI Listing
January 2019

Effectiveness of early use of fidaxomicin in preventing recurrence of Clostridium difficile infection.

J Hosp Infect 2019 Jan 17. Epub 2019 Jan 17.

Centre for Clinical Infection and Diagnostics Research (CIDR), Guy's & St Thomas' NHS Foundation Trust and King's College, London, UK.

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http://dx.doi.org/10.1016/j.jhin.2019.01.013DOI Listing
January 2019

Influence of bacterial resistance on mortality in intensive care units: A registry study from 2000 to 2013 (IICU Study).

J Hosp Infect 2019 Jan 16. Epub 2019 Jan 16.

Department of Anaesthesiology and Critical Care, University Hospital of Caen, F-14000 Caen, France; Normandie Université, Esplanade de La Paix, CS 14 032, F-14 000 Caen, France. Electronic address:

Introduction: Bacterial resistance to antibiotics is a daily concern in intensive care units. However, few data are available concerning the clinical consequences of in vitro defined resistance. This study aimed to compare the mortality of patients with nosocomial infections according to bacterial resistance profiles. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01956701193001
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http://dx.doi.org/10.1016/j.jhin.2019.01.011DOI Listing
January 2019
3 Reads

Clinical prediction models for ESBL-Enterobacteriaceae colonization or infection: A systematic review.

J Hosp Infect 2019 Jan 14. Epub 2019 Jan 14.

Department of Primary Care Medicine, Faculty of Medicine, University of Malaya, Jalan Universiti, 50603 Kuala Lumpur, Wilayah Persekutuan, Kuala Lumpur, Malaysia.

Objectives: We aimed to identify and critically appraise existing clinical prediction models of extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-EKP) infection or colonization.

Methods: Electronic databases, reference lists, and citations were searched from inception to April 2018. We included papers in any language describing the development or validation, or both, of models and scores to predict the risk of ESBL-EKP infection or colonization. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01956701193001
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http://dx.doi.org/10.1016/j.jhin.2019.01.012DOI Listing
January 2019
3 Reads

Predictive models of surgical site infections after coronary surgery: insights from a validation study on 7090 consecutive patients.

J Hosp Infect 2019 Jan 15. Epub 2019 Jan 15.

Cardio-Thoracic and Vascular Department, Trieste University Hospital, Trieste, Italy.

Background: The role of specific scoring systems in predicting risk of surgical site infections (SSIs) after coronary artery bypass grafting (CABG) has not been established.

Aim: To validate the most relevant predictive systems for SSIs after CABG.

Methods: Five predictive systems (eight models) for SSIs after CABG were evaluated retrospectively in 7090 consecutive patients undergoing isolated (73. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01956701193001
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http://dx.doi.org/10.1016/j.jhin.2019.01.009DOI Listing
January 2019
3 Reads

Healthcare worker screening in Streptococcus pyogenes outbreaks using throat and perineal swabs.

J Hosp Infect 2019 Jan 12. Epub 2019 Jan 12.

Department of Clinical Microbiology, Nottingham University Hospitals NHS Trust, Nottingham, UK.

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http://dx.doi.org/10.1016/j.jhin.2019.01.010DOI Listing
January 2019

Vancomycin use in surrounding patients during critical illness and risk for persistent colonization with vancomycin-resistant Enterococcus.

J Hosp Infect 2019 Jan 11. Epub 2019 Jan 11.

Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.

The optimal duration of contact precautions for vancomycin-resistant enterococcus (VRE)-colonized patients is uncertain and individual patient characteristics alone may not predict risk of prolonged colonization. Using a cohort of adult patients who underwent testing for VRE at intensive care unit (ICU) admission, we tested the association between local (unit-level) vancomycin use and persistent colonization with VRE. Higher unit-level vancomycin use significantly prolonged VRE colonization (P=0. Read More

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http://dx.doi.org/10.1016/j.jhin.2019.01.008DOI Listing
January 2019

An evaluation of the electronic reporting system for the enhanced surveillance of carbapenemase-producing Gram-negative bacteria in England.

J Hosp Infect 2019 Jan 12. Epub 2019 Jan 12.

Field Service, National Infection Service, Public Health England, UK; NIHR Health Protection Research Unit in Evaluation of Interventions, University of Bristol, Bristol, UK.

Background: An electronic reporting system (ERS) for the enhanced surveillance of carbapenemase-producing Gram-negative bacteria (CPGNB) was launched by Public Health England in May 2015.

Aim: This evaluation aimed to assess uptake, timeliness and completeness of data provided and explore potential barriers and facilitators to adopting the system.

Methods: The evaluation comprised a retrospective analysis of surveillance data and semi-structured interviews with ERS users. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01956701193000
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http://dx.doi.org/10.1016/j.jhin.2019.01.005DOI Listing
January 2019
7 Reads

Water-borne infections and warming the sterile water for washing high-risk infants on neonatal intensive care units.

Authors:
B Cherian E Price

J Hosp Infect 2019 Jan 9. Epub 2019 Jan 9.

Consultant Microbiologist (Retired), London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jhin.2019.01.006DOI Listing
January 2019
1 Read

Effects of a disinfection device on colonization of sink drains and patients during a prolonged outbreak of multidrug-resistant Pseudomonas aeruginosa in an intensive care unit.

J Hosp Infect 2019 Jan 9. Epub 2019 Jan 9.

Department of Medical Microbiology, Leiden University Medical Centre, Leiden, the Netherlands.

Background: Sink drains in intensive care units (ICUs) are frequently colonized with bacteria such as Pseudomonas aeruginosa.

Aim: To study the influence of installing disinfecting devices on sink drains on colonization of sinks and patients in an ICU during a prolonged outbreak of multidrug-resistant P. aeruginosa. Read More

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http://dx.doi.org/10.1016/j.jhin.2019.01.003DOI Listing
January 2019
1 Read

Detection of hepatitis C virus in an exhumed body identified the origin of a nosocomial transmission that caused multiple fatal diseases.

J Hosp Infect 2019 Jan 8. Epub 2019 Jan 8.

Institute of Microbiology, School of Medicine, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy.

Background: Medico-legal conflicts arise when it is difficult to prove the cause of nosocomial infections.

Aim: To report an outbreak of patient-to-patient transmission of hepatitis C virus (HCV) through the repeated use of a multi-dose saline flask during the rinsing of central venous catheters.

Methods: Blood samples were taken from each patient for the comparative analysis of their HCV RNA strains. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01956701193000
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http://dx.doi.org/10.1016/j.jhin.2019.01.004DOI Listing
January 2019
5 Reads

Nosocomial outbreak of extended-spectrum β-lactamase-producing Enterobacter cloacae among cardiothoracic surgical patients: causes and consequences.

J Hosp Infect 2019 Jan 7. Epub 2019 Jan 7.

Infection Control Unit, CHU UCL Namur, Yvoir, Belgium; National Reference Centre for Monitoring Antimicrobial Resistance in Gram-Negative Bacteria, CHU UCL Namur, Yvoir, Belgium.

Background: Enterobacteriaceae are recognized as leading pathogens of healthcare-associated infections.

Aim: To report the investigation of a nosocomial outbreak of extended-spectrum β-lactamase-producing Enterobacter cloacae affecting cardiothoracic surgery patients in a Belgian academic hospital.

Methods: Cases were defined based on epidemiological and microbiological investigations, including molecular typing using repetitive element-based polymerase chain reaction and multi-locus sequence typing. Read More

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http://dx.doi.org/10.1016/j.jhin.2019.01.001DOI Listing
January 2019
1 Read

Nosocomial Mycobacterium tuberculosis transmission by brief casual contact identified using comparative genomics.

J Hosp Infect 2019 Jan 7. Epub 2019 Jan 7.

Yamagata Prefectural Institute of Public Health, Yamagata, Japan; Murayama Public Health Centre, Yamagata, Japan.

This paper reports a case of nosocomial transmission of Mycobacterium tuberculosis by brief casual contact. Routine variable number tandem repeat typing in Yamagata Prefecture, Japan found that M. tuberculosis clinical isolates from two patients showed indistinguishable genotypes. Read More

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http://dx.doi.org/10.1016/j.jhin.2019.01.002DOI Listing
January 2019

Prevention of healthcare-associated invasive aspergillosis during hospital construction/renovation works.

J Hosp Infect 2019 Jan 7. Epub 2019 Jan 7.

Department of Clinical Microbiology, Trinity College Dublin, Dublin, Ireland; Department of Microbiology, St James's Hospital, Dublin, Ireland.

The association between healthcare-associated invasive aspergillosis and hospital construction/building works is well recognized. This infection can cause significant morbidity and mortality and imposes a substantial burden on the healthcare system. The population of patients at risk for this opportunistic infection has expanded and multi-triazole drug resistance has emerged globally. Read More

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http://dx.doi.org/10.1016/j.jhin.2018.12.020DOI Listing
January 2019
1 Read

The effect of using Fidaxomicin on recurrent Clostridium difficile infection?

J Hosp Infect 2019 Jan 4. Epub 2019 Jan 4.

University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital Birmingham, Edgbaston, Birmingham, B15 2WB, UK; Institute of Microbiology and Infection, The University of Birmingham, Edgbaston, Birmingham, UK. Electronic address:

Fidaxomicin is a macrocyclic antibiotic licensed for treating Clostridium difficile infection (CDI). In the UK, fidaxomicin is often reserved for severe CDI or recurrences. At Queen Elizabeth Hospital Birmingham, all courses of fidaxomicin during 2017/18 were reviewed. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01956701183072
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http://dx.doi.org/10.1016/j.jhin.2018.12.018DOI Listing
January 2019
5 Reads

A quality improvement initiative for improving hospital visitor hand hygiene.

J Hosp Infect 2019 Jan 4. Epub 2019 Jan 4.

Johns Hopkins Bayview Medical Center, Division of Geriatric Medicine and Gerontology, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.jhin.2018.12.019DOI Listing
January 2019

Can guidelines for the control of multi-drug-resistant Gram-negative organisms be put into practice? A national survey of guideline compliance and comparison of available guidelines.

J Hosp Infect 2019 Jan 5. Epub 2019 Jan 5.

School of Medicine, University College Dublin, Dublin 4, Ireland; Department of Clinical Microbiology, St Vincent's University Hospital, Dublin 4, Ireland.

Multi-drug-resistant Gram-negative organisms (MDRGNO) are an emerging global threat, reflected in the increasing incidence of infections in Ireland and elsewhere. The response to this threat has been the development of Infection Prevention and Control (IPC) guidelines. A survey of IPC teams in Ireland was undertaken to assess compliance with national guidelines. Read More

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http://dx.doi.org/10.1016/j.jhin.2018.12.017DOI Listing
January 2019

Monitoring healthcare-associated infections and antimicrobial use at regional level through repeated point prevalence surveys: what can be learnt?

J Hosp Infect 2018 Dec 29. Epub 2018 Dec 29.

Department of Medicine, University of Udine, Udine, Italy; Azienda Sanitaria Universitaria Integrata di Udine, Udine, Italy.

Background: Healthcare-associated infections (HAIs) surveillance is an essential part of any infection prevention and control programme. Repeated point prevalence surveys (PPSs) according to European Centre for Disease Prevention and Control (ECDC) protocol have been implemented in all Friuli Venezia Giulia (FVG) region (Italy) acute hospitals to reduce and control HAIs.

Aim: Using the repeated PPSs within a regional-healthcare system (RHS) to promote and evaluate infection prevention and control (IPC) programmes. Read More

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http://dx.doi.org/10.1016/j.jhin.2018.12.016DOI Listing
December 2018
1 Read

Four steps to clean hospitals: LOOK, PLAN, CLEAN and DRY.

Authors:
S J Dancer A Kramer

J Hosp Infect 2018 Dec 27. Epub 2018 Dec 27.

Institute of Hygiene and Environmental Medicine, University Medicine Greifswald, Greifswald, Germany.

Background: Now that cleaning and decontamination are recognized as integral to infection control, it is timely to examine the process in more detail. This is because cleaning practices vary widely within healthcare districts, and it is likely that both time and energy are needlessly wasted with ill-defined duties. Furthermore, inadequate cleaning will not reduce the risk of infection but may even enhance it. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01956701183072
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http://dx.doi.org/10.1016/j.jhin.2018.12.015DOI Listing
December 2018
1 Read

Application of the Theoretical Domains Framework to identify factors that influence hand hygiene compliance in long-term care.

J Hosp Infect 2018 Dec 28. Epub 2018 Dec 28.

Infection Prevention and Control, Public Health Ontario, Toronto, ON, Canada; Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada; The Ottawa Hospital Research Institute, Ottawa, ON, Canada; Faculty of Medicine, University of Toronto, Toronto, ON, Canada.

Background: Healthcare worker (HCW) hand hygiene compliance is key to patient safety; however, compliance is suboptimal. Nevertheless hand hygiene compliance is not well studied in the long-term care setting.

Aim: To apply a behaviour change framework, the Theoretical Domains Framework (TDF), to identify modifiable facilitators and barriers for HCW hand hygiene compliance in long-term care settings. Read More

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http://dx.doi.org/10.1016/j.jhin.2018.12.014DOI Listing
December 2018
1 Read
2.544 Impact Factor

Acinetobacter - the trojan horse of infection control?

J Hosp Infect 2018 Dec 27. Epub 2018 Dec 27.

HCAI & AMR Division, National Infection Service, Public Health England, London, UK.

Background: Five cases of multi-resistant Acinetobacter baumanii (MRA) producing OXA-23 and OXA-51 occurred in a regional burn intensive care unit (BICU). Three were repatriated from other parts of the world (Dubai and Mumbai) and colonized on admission. Despite optimal precautions, two patients acquired MRA. Read More

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http://dx.doi.org/10.1016/j.jhin.2018.12.013DOI Listing
December 2018

Identifying hospital-acquired infections using retrospective record review from the Irish National Adverse Events Study (INAES) and European point prevalence survey case definitions.

J Hosp Infect 2019 Mar 24;101(3):313-319. Epub 2018 Dec 24.

Department of Geriatric & Stroke Medicine, RCSI and Beaumont Hospital, Dublin, Ireland.

Background: Point prevalence surveys (PPSs) collect data on hospital-acquired infections (HAIs) at one point in time but do not provide information on incidence over the entire admission or impact on patients or healthcare resources. Retrospective record review examines the entire admission to determine adverse event prevalence, incidence, preventability, physical impairment and additional length of stay.

Aim: To establish whether European HAI surveillance definitions can be applied to the Irish National Adverse Events Study (INAES) retrospective record review data to determine HAI burden. Read More

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http://dx.doi.org/10.1016/j.jhin.2018.12.011DOI Listing

Food for thought. Malnutrition risk associated with increased risk of healthcare-associated infection.

J Hosp Infect 2019 Mar 25;101(3):300-304. Epub 2018 Dec 25.

Department of Microbiology, Beaumont Hospital, Dublin, Ireland; Health Protection Surveillance Centre, Dublin, Ireland.

Background: Infection and malnutrition are interconnected. UK and Irish guidelines recommend the Malnutrition Universal Screening Tool (MUST) for nutritional risk screening. Patients with a MUST score of ≥2 are considered at high risk of malnutrition and referral for nutritional assessment is recommended. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01956701183071
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http://dx.doi.org/10.1016/j.jhin.2018.12.012DOI Listing
March 2019
10 Reads

Preoperative mechanical and oral antibiotic bowel preparation to reduce infectious complications of colorectal surgery - the need for updated guidelines.

J Hosp Infect 2019 Mar 21;101(3):295-299. Epub 2018 Dec 21.

Wirral University Teaching Hospital NHS Foundation Trust, Birkenhead, Wirral, UK.

Background: Increasing evidence indicates that combined mechanical and oral antibiotic bowel preparation reduces the infectious complications of colorectal surgery. Anecdotal evidence suggests the combination is rarely used in the UK and Europe.

Aim: To establish colorectal surgeons' current use and awareness of the benefits of such bowel preparation, and to identify decision-making influences surrounding preoperative bowel preparation. Read More

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http://dx.doi.org/10.1016/j.jhin.2018.12.010DOI Listing

Acetic acid as a decontamination method for ICU sink drains colonized by carbapenemase-producing Enterobacteriaceae and its effect on CPE infections.

J Hosp Infect 2018 Dec 21. Epub 2018 Dec 21.

Department of Microbiology, Ziekenhuis Netwerk Antwerpen, Antwerp, Belgium.

Background: Carbapenemase-producing Enterobacteriaceae (CPE) are emerging pathogens representing a major concern for public health. In Belgium, the OXA-48 carbapenemase resistance gene is identified most frequently. Sink drains in intensive care units (ICUs) are known to be colonized by Gram-negative bacilli. Read More

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http://dx.doi.org/10.1016/j.jhin.2018.12.009DOI Listing
December 2018
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Carbapenem-resistant Enterobacteriaceae dispersal from sinks is linked to drain position and drainage rates in a laboratory model system.

J Hosp Infect 2018 Dec 18. Epub 2018 Dec 18.

Biosafety, Air and Water Microbiology Group, National Infection Service, Public Health England, Salisbury, UK.

Background: Hospital sinks, waste traps and drains can harbour carbapenem-resistant Enterobacteriaceae (CRE).

Aim: To investigate the dispersal of CRE from sinks in which water delivered from the tap flows directly into the drain and from clinical handwash basins with the drain at the rear. The effect of fast and slow drainage rates was also assessed. Read More

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http://dx.doi.org/10.1016/j.jhin.2018.12.007DOI Listing
December 2018
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Implementation of the cobas Liat influenza point-of-care test into an emergency department during a high-incidence season: a retrospective evaluation following real-world implementation.

J Hosp Infect 2019 Mar 16;101(3):285-288. Epub 2018 Dec 16.

Infection Care Group, St George's University Hospitals NHS Foundation Trust, London, UK.

The cobas Liat influenza A/B and respiratory syncytial virus (RSV) assay (Liat) was used in the adult emergency department of a large London hospital from 21 January 2018 to 14 April 2018. Influenza was detected in 308 of 1027 (30%) samples tested; influenza A in 157 (15.3%), influenza B in 149 (14. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01956701183071
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http://dx.doi.org/10.1016/j.jhin.2018.12.008DOI Listing
March 2019
4 Reads

Association between excreta management and incidence of extended-spectrum β-lactamase-producing Enterobacteriaceae: role of healthcare workers' knowledge and practices.

J Hosp Infect 2018 Dec 14. Epub 2018 Dec 14.

MiHAR Lab, University of Nantes, Nantes, France; Bacteriology and Infection Control Department, Nantes University Hospital, Nantes, France. Electronic address:

Background: The spread of extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-PE) in healthcare environments has become a major public health threat in recent years.

Aim: To assess how healthcare workers (HCWs) manage excreta and the possible association with the incidence of ESBL-PE.

Methods: Eight hundred HCWs and 74 nurse-supervisors were questioned through two self-report questionnaires in order to assess their knowledge and practices, and to determine the equipment utilized for excreta management in 74 healthcare departments. Read More

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http://dx.doi.org/10.1016/j.jhin.2018.12.006DOI Listing
December 2018
2 Reads

What are the main drivers for public policies to prevent healthcare-associated infections?

J Hosp Infect 2019 Mar 13;101(3):292-294. Epub 2018 Dec 13.

Nottingham University Business School, Nottingham, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S01956701183068
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http://dx.doi.org/10.1016/j.jhin.2018.07.047DOI Listing
March 2019
13 Reads