2,303 results match your criteria Journal of HIV/AIDS Prevention in Children & Youth [Journal]


Towards UNAIDS Fast-Track goals: targeting priority geographic areas for HIV prevention and care in Zimbabwe.

AIDS 2019 Feb;33(2):305-314

Department of Public Health Medicine, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.

Introduction: Zimbabwe has made substantial progress towards the Joint United Nations Programme on HIV/AIDS (UNAIDS) targets of 90-90-90 by 2020, with 73% of people living with HIV diagnosed, 87% of those diagnosed on antiretroviral therapy (ART) and 86% of those on ART virally suppressed. Despite this exceptional response, more effort is needed to completely achieve the UNAIDS targets. Here, we conducted a detailed spatial analysis of the geographical structure of the HIV epidemic in Zimbabwe to include geographical prioritization as a key component of their overall HIV intervention strategy. Read More

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http://dx.doi.org/10.1097/QAD.0000000000002052DOI Listing
February 2019

Sexual risk behaviour among HIV-infected women in the first twelve months after delivery in South Africa.

J Psychol Afr 2018 3;28(4):330-335. Epub 2018 Jun 3.

Department of Psychiatry and Behavioural Sciences, University of Miami Miller School of Medicine, Miami, USA.

This study aimed to assess sexual risk behaviour and its social correlates in HIV-infected women living in rural South Africa at six and twelve months post-partum. Participants were 699 HIV-positive women recruited prenatally by systematic sampling from twelve community health centres in Mpumalanga province, South Africa (mean age = 28.4 years, SD = 5. Read More

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http://dx.doi.org/10.1080/14330237.2018.1435048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291218PMC

Assessment of the effectiveness of PMTCT program in eight service delivery points in North Central Nigeria.

HIV AIDS (Auckl) 2018 20;10:253-259. Epub 2018 Nov 20.

Hepatology Unit, Imperial College London, London, UK.

Background: Mother-to-child transmission (MTCT) of HIV is one of the commonest avenues through which infants are infected with HIV. To achieve an HIV-free generation, MTCT of HIV should be eliminated. Nigeria began prevention of mother-to-child transmission (PMTCT) services 13 years ago, but it still contributes to over one-third of global MTCT burden. Read More

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http://dx.doi.org/10.2147/HIV.S157685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251355PMC
November 2018

Life expectancy and years of life lost in HIV patients under the care of BandarAbbas Behavioral Disorders Counseling Center.

Nepal J Epidemiol 2017 Dec 31;7(4):702-712. Epub 2017 Dec 31.

Epidemiology and Biostatistics Department, Rafsanjan Medical School, Rafsanjan University of Medical Sciences, Rafsanjan, IR Iran.

Background: HIV epidemic is mostly targeted adults and has numerous negative health, social, economic, cultural and political consequences. In this study Life Expectancy (LE) and Average Years of Life Lost (AYLL) in HIV/AIDS patients are estimated.

Materials And Methods: In this descriptive study all the patients at the age of 18 and more under the care of BandarAbbas Behavioral Disorders Counseling Center (BBDCC) during 2005-2015 are included. Read More

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https://www.nepjol.info/index.php/NJE/article/view/20627
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http://dx.doi.org/10.3126/nje.v7i4.20627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204067PMC
December 2017
2 Reads

[Chinese guidelines for diagnosis and treatment of HIV/AIDS (2018)].

Authors:

Zhonghua Nei Ke Za Zhi 2018 Dec;57(12):867-884

(AIDS) is an important public health problem in China. In 2005, the first edition of the guidelines for the diagnosis and treatment of AIDS was formulated by the AIDS Professional Group of Society of Infectious Diseases of Chinese Medical Association, which was updated twice in 2011 and 2015. The fourth edition of the guidelines in 2018 is revised on the basis of national clinical practice and the latest research studies. Read More

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December 2018
6 Reads

Eliminating perinatal HIV in the United States: mission possible?

AIDS 2018 Nov 19. Epub 2018 Nov 19.

ICAP at Columbia University, Mailman School of Public Health and Vagelos College of Physicians & Surgeons, Columbia University, New York, NY.

In 2015, only 53 infants born in the United States acquired HIV, the lowest recorded number of perinatal HIV infections. Recognizing this significant achievement, we must acknowledge that the United States has not yet reached the goal of eliminating perinatal HIV transmission. This manuscript describes different approaches to perinatal HIV preventive services among five states and the District of Columbia as case studies. Read More

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http://dx.doi.org/10.1097/QAD.0000000000002080DOI Listing
November 2018
5.550 Impact Factor

HIV diagnosis disclosure to infected children and adolescents; challenges of family caregivers in the Central Region of Ghana.

BMC Pediatr 2018 Nov 22;18(1):365. Epub 2018 Nov 22.

Kirkhoff School of Nursing, Grand Valley State University, Michigan, USA.

Background: Disclosure of Human Immunodeficiency Virus (HIV) to infected older children and adolescents is essential for both personal health maintenance and HIV prevention within the larger population. Non-disclosure of HIV status has been identified as one of the potential barriers to optimum adherence especially in children and adolescents. Like many other countries in the SSA region, Ghana has significant number of children and adolescents infected by HIV, who have increased survival times, due to increased access to ART. Read More

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http://dx.doi.org/10.1186/s12887-018-1330-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251211PMC
November 2018
2 Reads

Quality of antenatal care services in Rwanda: assessing practices of health care providers.

BMC Health Serv Res 2018 Nov 19;18(1):865. Epub 2018 Nov 19.

Section of Epidemiology and Social Medicine (EPSO), Department of Public Health and Community Medicine, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.

Background: Although most pregnant women in Rwanda visit antenatal care (ANC) clinics, little has been studied about the quality of services being provided. We investigated the ANC providers' (HCPs) current practices in relation to prevention, management and referral of maternal conditions as well as the information provided to pregnant women attending ANC services in Rwanda.

Methods: This facility-based, cross-sectional study included 312 ANC providers as participants and a review of 605 ANC medical records from 121 health centers. Read More

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https://bmchealthservres.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/s12913-018-3694-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245627PMC
November 2018
4 Reads

The effectiveness of PEPFAR's funding for women and children with HIV/AIDS.

Authors:
Yiyeon Kim

Int J Health Plann Manage 2018 Nov 19. Epub 2018 Nov 19.

Department of Political Science & International Studies, Yonsei University, Seoul, South Korea.

Has President's Emergency Plan for AIDS Relief's (PEPFAR) funding been effective in reducing the rate of HIV new infections and AIDS-related deaths among women and children? While previous studies have found HIV/AIDS aid to be ineffective and PEPFAR funding to produce negative externalities, there is lack of empirical examination of the impact of PEPFAR on women and children despite the emphasis on prevention of mother-to-child transmission of HIV during the Bush and Obama administrations. Using descriptive analysis and difference-in-differences (DID) regression, this study finds that PEPFAR's funding has reduced the HIV new infections and AIDS-related death rates of women and children for both focus countries and recipient countries, which are those that were added in a second phase. These findings show that PEPFAR's strategy for women and children has been effective and that it should be continued. Read More

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http://dx.doi.org/10.1002/hpm.2706DOI Listing
November 2018
5 Reads

The pull of soccer and the push of Xhosa boys in an HIV and drug abuse intervention in the Western Cape, South Africa.

SAHARA J 2018 Dec;15(1):187-199

b Center of Expertise on Women's Health, Gender and Empowerment , University of California Global Health Institute , San Francisco , CA , USA.

There is growing interest in engaging men and boys in health and development programmes targeting the intersection of HIV risk, substance abuse, and violence. Understanding the conceptualisations of masculinities or masculine identities that shape both behaviours and opportunities for intervention is central to advancing the global agenda to engage men in health and development interventions. This paper examines an intervention using soccer and job training to engage and deliver activities for HIV prevention, substance abuse, and gender-based violence in a South African township. Read More

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http://dx.doi.org/10.1080/17290376.2018.1541024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237168PMC
December 2018

Unmet need for contraception among HIV-positive women in Ile-Ife, Nigeria.

Trop Doct 2018 Nov 12:49475518809605. Epub 2018 Nov 12.

3 Professor, Department of Paediatrics, Obafemi Awolowo University, Ile Ife, Nigeria.

As mother-to-child transmission of HIV is difficult to predict and also hard to prevent in practice, pregnancy among women living with HIV/AIDS (WHA) needs to be taken with considerable aforethought. The prevention of unwanted pregnancy among WHA is therefore a public health issue. The aim of our study was to determine the unmet need for contraception among HIV-positive women and the associated factors. Read More

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http://journals.sagepub.com/doi/10.1177/0049475518809605
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http://dx.doi.org/10.1177/0049475518809605DOI Listing
November 2018
6 Reads

Cash Transfers, Young Women's Economic Well-Being, and HIV Risk: Evidence from HPTN 068.

AIDS Behav 2018 Nov 10. Epub 2018 Nov 10.

Carolina Population Center, University of North Carolina, Chapel Hill, NC, USA.

Despite the large interest in economic interventions to reduce HIV risk, little research has been done to show whether there are economic gains of these interventions for younger women and what intermediary role economic resources play in changing participants' sexual behavior. This paper contributes to this gap by examining the impacts of a conditional cash transfer (CCT) for young women in South Africa on young women's economic resources and the extent to which they play a role in young women's health and behavior. We used data from HIV Prevention Trials Network 068 study, which provided transfers to young women (in addition to their parents) conditional on the young woman attending at least 80% of school days in the previous month. Read More

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http://dx.doi.org/10.1007/s10461-018-2329-5DOI Listing
November 2018
2 Reads

Study of human rights violations faced by women who use drugs in Estonia.

Harm Reduct J 2018 Nov 6;15(1):54. Epub 2018 Nov 6.

Estonian Association of People Who Use Psychotropic Substances (LUNEST), Pärnu Maantee 130-25, 11317, Tallinn, Estonia.

Background: Estonia continues to have the highest prevalence of HIV among people who inject drugs, and the highest overdose mortality, in the European Union. In August 2017, the Eurasian Harm Reduction Association (EHRA), the Canadian HIV/AIDS Legal Network (CHALN), and the Estonian Association of People Who Use Psychotropic Substances (LUNEST) conducted a study in Estonia to assess the situation regarding the human rights of women who use drugs and/or living with HIV.

Methods: The research methodology, developed by EHRA and CHALN, comprised in-depth interviews with 38 drug-dependent women conducted between August 8 and 14, 2017, in Tallinn and Ida-Viru county. Read More

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https://harmreductionjournal.biomedcentral.com/articles/10.1
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http://dx.doi.org/10.1186/s12954-018-0259-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220502PMC
November 2018
3 Reads

Towards achieving the fast-track targets and ending the epidemic of HIV/AIDS in Ethiopia: Successes and challenges.

Int J Infect Dis 2019 Jan 1;78:57-64. Epub 2018 Nov 1.

School of Public Health, the University of Queensland, Brisbane, Australia.

Background: Ethiopia has adopted the global plan to end the epidemic of HIV/AIDS. The aim of this study was to assess the progress made towards achieving this plan.

Methods: A review and analysis of national population-based surveys, surveillance, and routine programme data was executed. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S12019712183457
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http://dx.doi.org/10.1016/j.ijid.2018.10.022DOI Listing
January 2019
4 Reads

Awareness and Utilization: Prevention of Mother-to-Child Transmission (PMTCT) Services among Primigravid Women attending Primary Health Care Facilities in Zaria, North-Western Nigeria.

West Afr J Med 2018 Sep-Dec;35(3):144-152

Department of Community Medicine, Kaduna State University, Nigeria.

Background: Nigeria with an estimated population of 193 million is Second to South Africa in the number of people living with Human Immune Deficiency Virus and Acquired Immune Deficiency Syndrome (HIV/AIDS) worldwide, representing 9% of the global burden of the disease. The objective of this study is to determine the awareness, knowledge and utilization of PMTCT services before first pregnancy in the study population, which is a critical prong 1 PMTCT strategy to prevent and control the vertical transmission of this pandemic infection.

Methods: An analytical cross-sectional study conducted in February-April 2016 among 300 Primigravid women selected by the cluster sampling technique from six Primary Health Care (PHC) facilities that offered PMTCT services out of a list of 25 PHC facilities in Zaria LGA at the time of the survey. Read More

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November 2018
3 Reads

Setting research priorities to achieve long-term health targets in Iran.

J Glob Health 2018 Dec;8(2):020702

Engineering Seismology Department, International Institute of Earthquake Engineering and Seismology (IIEES), Tehran, Iran.

Background: In 2015, it was estimated that the burden of disease in Iran comprised of 19 million disability-adjusted life years (DALYs), 74% of which were due to non-communicable diseases (NCDs). The observed leading causes of death were cardiovascular diseases (41.9%), neoplasms (14. Read More

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http://jogh.org/documents/issue201802/jogh-08-020702.pdf
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http://dx.doi.org/10.7189/jogh.08.020702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188089PMC
December 2018
10 Reads

Hepatitis C Virus in Women of Childbearing Age, Pregnant Women, and Children.

Am J Prev Med 2018 Nov;55(5):633-641

Division of Viral Hepatitis, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia.

Introduction: Perinatal transmission is an increasingly important mode of hepatitis C virus transmission. The authors characterized U.S. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07493797183194
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http://dx.doi.org/10.1016/j.amepre.2018.05.029DOI Listing
November 2018
6 Reads

Generalizing the per-protocol treatment effect: The case of ACTG A5095.

Clin Trials 2018 Oct 17:1740774518806311. Epub 2018 Oct 17.

1 Department of Epidemiology, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Background Intention-to-treat comparisons of randomized trials provide asymptotically consistent estimators of the effect of treatment assignment, without regard to compliance. However, decision makers often wish to know the effect of a per-protocol comparison. Moreover, decision makers may also wish to know the effect of treatment assignment or treatment protocol in a user-specified target population other than the sample in which the trial was fielded. Read More

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http://journals.sagepub.com/doi/10.1177/1740774518806311
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http://dx.doi.org/10.1177/1740774518806311DOI Listing
October 2018
7 Reads

Determinants of disclosure and non-disclosure of HIV-positive status, by pregnant women in rural South Africa.

SAHARA J 2018 12;15(1):155-163

a HIV/Aids, STI and TB Research Programme , Human Sciences Research Council , Pretoria , South Africa.

Disclosure of HIV status remains one of the major challenges to the effectiveness of the prevention of mother to child transmission of HIV in rural areas in South Africa. This study aimed at assessing the determinants of HIV status disclosure among HIV infected pregnant women who have disclosed their HIV status to someone, as well as among those who have disclosed to their partners. Cross-sectional data was collected from 673 HIV sero-positive pregnant women receiving antenatal care services at 12 Community Health Centers in Mpumalanga province. Read More

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https://www.tandfonline.com/doi/full/10.1080/17290376.2018.1
Publisher Site
http://dx.doi.org/10.1080/17290376.2018.1529613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197005PMC
December 2018
1 Read

An assessment of antiretroviral drug initiation to pregnant women of unknown HIV status during labour and delivery in Cameroon.

Afr J AIDS Res 2018 Sep 14;17(3):265-271. Epub 2018 Oct 14.

i Department of Family Health, Ministry of Public Health , Yaoundé , Cameroon.

Background: Evidence from previous research has shown that antiretroviral (ARV) drug initiation to seropositive pregnant women could significantly contribute to eliminating new paediatric infections even when started during labour and delivery. This study therefore seeks to assess missed opportunities for ARV initiation during this critical period of pregnancy to improve outcomes of the prevention of mother-to-child transmission (PMTCT) programmes in Cameroon.

Methods: A retrospective study was conducted on the 2014 PMTCT data for labour and delivery among pregnant women of unknown HIV status within health facilities in six regions of Cameroon (428 eligible facilities). Read More

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https://www.tandfonline.com/doi/full/10.2989/16085906.2018.1
Publisher Site
http://dx.doi.org/10.2989/16085906.2018.1515780DOI Listing
September 2018
2 Reads

A Missing Link: HIV-/AIDS-Related mHealth Interventions for Health Workers in Low- and Middle-Income Countries.

Curr HIV/AIDS Rep 2018 Dec;15(6):414-422

Department of Global Health, University of Washington, Seattle, WA, 98105, USA.

Purpose Of Review: Through a review of the peer-reviewed and gray literature on HIV mobile health (mHealth) tools for health workers and in-depth interviews with mHealth leaders in the field, we provide a synthesis of current work and propose mHealth research priorities for HIV prevention, care, and treatment.

Recent Findings: Significant investment in implementation research and bringing together researchers capable of identifying drivers of successful implementation and industry leaders capable of bringing efficacious tools to scale are needed to move this area forward. Effective and appropriate technologies to support health systems in the prevention and treatment of HIV/AIDS in low- and middle-income countries are needed to improve the efficiency and quality of health service delivery and ultimately improve health outcomes. Read More

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http://dx.doi.org/10.1007/s11904-018-0416-xDOI Listing
December 2018
11 Reads

Integration of HIV and reproductive health services in public sector facilities: analysis of client flow data over time in Kenya.

BMJ Glob Health 2018 14;3(5):e000867. Epub 2018 Sep 14.

Department of Global Health and Development, London School of Hygiene & Tropical Medicine, London, UK.

Introduction: Integration of HIV/AIDS with reproductive health (RH) services can increase the uptake and efficiency of services, but gaps in knowledge remain about the practice of integration, particularly how provision can be expanded and performance enhanced. We assessed the extent and nature of service integration in public sector facilities in four districts in Kenya.

Methods: Between 2009 and 2012, client flow assessments were conducted at six time points in 24 government facilities, purposively selected as intervention or comparison sites. Read More

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http://dx.doi.org/10.1136/bmjgh-2018-000867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144905PMC
September 2018

HIV Vertical transmission in Rio de Janeiro, Brazil - does the distance matter?

AIDS Care 2018 Sep 6:1-4. Epub 2018 Sep 6.

d Departamento de Ciências Biológicas, Escola Nacional de Saúde Pública Sergio Arouca , Fundação Oswaldo Cruz , Rio de Janeiro , Brazil.

Mother-to-child transmission (MTCT) is the main route of transmission for HIV among under 5 children in Brazil. National data indicate that missed opportunities for HIV prevention of MTCT are still common in antenatal care (ANC). We studied variables related to target process indicators in a cohort of HIV exposed children. Read More

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http://dx.doi.org/10.1080/09540121.2018.1515466DOI Listing
September 2018

Expanding home-based management of malaria to all age groups in Rwanda: analysis of acceptability and facility-level time-series data.

Trans R Soc Trop Med Hyg 2018 Nov;112(11):513-521

Office of the Director General, Rwanda Biomedical Center, Kigali, Rwanda.

Background: In response to a resurgence of malaria in Rwanda, home-based management (HBM) was expanded to enable community-health workers (CHWs) to provide malaria treatment to patients of all ages. We assessed the effect of the expanded HBM program on malaria case presentations at health facilities.

Methods: Services provided by CHWs and health facility presentations among individuals >5 y of age were considered. Read More

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http://dx.doi.org/10.1093/trstmh/try093DOI Listing
November 2018
1 Read

Short Communication: Reduced Nevirapine Concentrations Among HIV-Positive Women Receiving Mefloquine for Intermittent Preventive Treatment for Malaria Control During Pregnancy.

AIDS Res Hum Retroviruses 2018 Nov 17;34(11):912-915. Epub 2018 Oct 17.

3 Malaria Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention , Atlanta, Georgia .

Clinical trials demonstrated intermittent preventive treatment in pregnancy with mefloquine (MQ) reduced malaria rates among pregnant women, yet an unexpected higher risk of mother-to-child transmission (MTCT) of HIV among HIV-positive women receiving MQ has also been observed. To determine if interactions between antiretroviral drugs (ARVs) and MQ could contribute to the increased MTCT observed in women receiving MQ, we performed a retrospective cross-sectional analysis of ARV plasma concentrations in peripheral blood (maternal plasma) and cord blood (cord plasma) collected at delivery from 186 mothers participating in a randomized clinical trial of MQ (n = 102) compared with placebo (n = 84) in Kenya. Plasma zidovudine (AZT), lamivudine (3TC), and nevirapine (NVP) concentrations were measured by high-performance liquid chromatography-tandem mass spectrometry. Read More

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http://dx.doi.org/10.1089/AID.2018.0042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238614PMC
November 2018
1 Read
2.330 Impact Factor

Theory-Based Behavioral Intervention Increases Mother-Son Communication About Sexual Risk Reduction Among Inner-City African-Americans.

J Adolesc Health 2018 Oct 23;63(4):497-502. Epub 2018 Aug 23.

College of Nursing and Health Professions, Drexel University, Philadelphia, Pennsylvania.

Purpose: African-American adolescent males are at increased risk for HIV, yet there are few sexual risk-reduction interventions targeting this population. Interventions that include mothers can influence parentingbehaviors and in turn, reduce risky behaviors in adolescents. This study tests the efficacy of the Mother-Son Health Promotion Project at increasing mother-son communication about sexual risk reduction. Read More

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http://dx.doi.org/10.1016/j.jadohealth.2018.04.017DOI Listing
October 2018
2 Reads

Evaluation of Specimen Types for Pima CD4 Point-of-Care Testing: Advantages of Fingerstick Blood Collection into an EDTA Microtube.

PLoS One 2018 23;13(8):e0202018. Epub 2018 Aug 23.

United States Centers for Disease Control & Prevention, Center for Global Health, Division of Global HIV/AIDS, Atlanta, Georgia, United States of America.

Introduction: Effective point-of-care testing (POCT) is reliant on optimal specimen collection, quality assured testing, and expedited return of results. Many of the POCT are designed to be used with fingerstick capillary blood to simplify the blood collection burden. However, fingerstick blood collection has inherent errors in sampling. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0202018PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107158PMC
August 2018
1 Read

Effect of a multicomponent behavioural PMTCT cluster randomised controlled trial on HIV stigma reduction among perinatal HIV positive women in Mpumalanga province, South Africa.

SAHARA J 2018 12;15(1):80-88

c Department of Psychiatry & Behavioral Sciences , University of Miami Miller School of Medicine , Miami , Florida , USA.

Background: We evaluate the impact a multicomponent, behavioural, prevention of mother to child transmission (PMTCT), cluster randomised controlled trial on HIV stigma reduction among perinatal HIV infected women in rural South Africa.

Methods: In a cluster randomised controlled trial, twelve community health centres (CHCs) in Mpumalanga Province, South Africa, were randomised; pregnant women living with HIV enrolled received either: A Standard Care (SC) condition plus time-equivalent attention-control on disease prevention (SC; 6 CHCs; n =357), or an Enhanced Intervention (EI) condition of SC PMTCT plus the 'Protect Your Family' intervention (EI; 6 CHCs; n =342). HIV-infected pregnant women in the SC attended four antenatal and two postnatal video sessions; those in the EI, four antenatal and two postnatal group PMTCT sessions, including stigma reduction, led by trained lay health workers. Read More

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http://dx.doi.org/10.1080/17290376.2018.1510787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116698PMC
December 2018
12 Reads

Study protocol of "Our Choice": a randomized controlled trial of the integration of safer conception counseling to transform HIV family planning services in Uganda.

Implement Sci 2018 08 14;13(1):110. Epub 2018 Aug 14.

RAND Corporation, Santa Monica, CA, USA.

Background: About 40% of HIV-positive women in sub-Saharan Africa become pregnant post-diagnosis. Despite about half of their pregnancies being planned, safer conception methods (SCM) are underutilized among serodiscordant couples, partially due to the fact that safer conception counseling (SCC) has not been integrated into routine HIV family planning (FP) services.

Methods: Our Choice is a comprehensive FP intervention that promotes unbiased childbearing consultations to ensure clients receive SCC or contraception services to achieve their desired reproductive goals. Read More

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https://implementationscience.biomedcentral.com/articles/10.
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http://dx.doi.org/10.1186/s13012-018-0793-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092849PMC
August 2018
10 Reads

Psychosocial predictors of consistent condom use among migrant road construction workers in the Southwest Region of Cameroon using the Health Belief Model.

Pan Afr Med J 2018 18;29:215. Epub 2018 Apr 18.

HIV/AIDS Prevention Research Network Cameroon (HIVPREC), Kumba, South-west Region, Cameroon.

Introduction: A significant proportion of road construction workers are migrants and prone to HIV infection. This study investigated the psychosocial predictors of consistent condom use among migrant road construction workers in the South-west region of Cameroon using the Health Belief Model (HBM) as the theoretical framework.

Methods: A cross-sectional survey of a stratified sample of 254 road construction workers was conducted at construction sites along the Kumba-Mamfe road in the South-west region of Cameroon in December 2015. Read More

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http://dx.doi.org/10.11604/pamj.2018.29.215.15130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080963PMC

Hepatitis C virus infection in children: How do we prevent it and how do we treat it?

Expert Rev Anti Infect Ther 2018 Sep 21;16(9):689-694. Epub 2018 Aug 21.

a Division of Reproductive Health , National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention , Atlanta , GA , USA.

Introduction: Hepatitis C virus (HCV) infection is an important contributor to the worldwide burden of liver-related morbidity and mortality. Mother-to-child transmission of HCV ranges from 6 to 11% in different populations globally, but accurate estimates on the burden of pediatric HCV infection are limited because screening approaches are not consistent. Areas covered: The advent of new direct-acting antiviral agents that achieve very high rates of sustained virologic response (representing virologic cure) with short (i. Read More

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http://dx.doi.org/10.1080/14787210.2018.1509707DOI Listing
September 2018
2 Reads

Agony resulting from cultural practices of canine bud extraction among children under five years in selected slums of Makindye: a cross sectional study.

BMC Oral Health 2018 Aug 7;18(1):133. Epub 2018 Aug 7.

Clarke International University (CIU) formerly International Health Sciences University (IHSU), Plot 4686, St. Barnabas Road Kisugu-Namuwongo, P.O Box 7782, Kampala, Uganda.

Background: Canine Bud Extraction (CBE) is a process of removing or gouging children's healthy canine tooth buds embedded underneath the gum using traditional unsterilized tools. The practice of CBE commonly known as false teeth removal continues to be an adopted cultural intervention of choice, in the prevention of morbidity and mortality from common childhood illnesses. However, it is a practice against the rights of the children with serious consequences. Read More

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http://dx.doi.org/10.1186/s12903-018-0599-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081831PMC
August 2018
1 Read

Pattern of paediatric HIV status disclosure in coastal Karnataka.

Indian J Med Res 2018 05;147(5):501-506

National AIDS Control Organisation, Ministry of Health and Family Welfare, New Delhi, India.

Background & Objectives: Karnataka is a high HIV prevalent State in India. Although benefits have been shown by disclosing the HIV status to the child, information regarding HIV status disclosure in Karnataka is limited. Hence, this study was conducted to estimate the proportion of children who had been disclosed of their HIV status and its pattern among those who visited the district antiretroviral therapy (ART) centre in coastal Karnataka. Read More

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http://dx.doi.org/10.4103/ijmr.IJMR_1821_15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094512PMC

Feasibility and utility of active case finding of HIV-infected children and adolescents by provider-initiated testing and counselling: evidence from the Laquintinie hospital in Douala, Cameroon.

BMC Pediatr 2018 Aug 3;18(1):259. Epub 2018 Aug 3.

Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon.

Background: Universal HIV testing and treatment of infected children remain challenging in resource-limited settings (RLS), leading to undiagnosed children/adolescents and limited access to pediatric antiretroviral therapy (ART). Our objective was to evaluate the feasibility of active cases finding of HIV-infected children/adolescents by provider-initiated testing and counseling in a health facility.

Methods: A cross-sectional prospective study was conducted from January through April 2016 at 6 entry-points (inpatient, outpatient, neonatology, immunization/family planning, tuberculosis, day-care units) at the Laquintinie Hospital of Douala (LHD), Cameroon. Read More

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https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887
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http://dx.doi.org/10.1186/s12887-018-1235-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090739PMC
August 2018
16 Reads

Epidemiology and aetiologies of cryptococcal meningitis in Africa, 1950-2017: protocol for a systematic review.

BMJ Open 2018 Jul 30;8(7):e020654. Epub 2018 Jul 30.

Department of Medical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.

Introduction: Cryptococcal meningitis is a neglected disease and an AIDS-defining illness, responsible for 15% of all AIDS-related deaths globally. In 2014, the estimated number of incident cryptococcal meningitis cases was 223 100, with 73% of them occurring in Africa. Currently available data on the prevalence, incidence, aetiologies and mortality of cryptococcal meningitis across Africa are sparse and of limited quality. Read More

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http://dx.doi.org/10.1136/bmjopen-2017-020654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067404PMC

Cycle of violence among young Kenyan women: The link between childhood violence and adult physical intimate partner violence in a population-based survey.

Child Abuse Negl 2018 Oct 21;84:45-52. Epub 2018 Jul 21.

Division of Global HIV/AIDS & Tuberculosis, U.S. Centers for Disease Control and Prevention, PO Box 606-00621 Nairobi, Kenya. Electronic address:

The aim of the current analysis is to elucidate the link between childhood experiences of violence and physical intimate partner violence in young adulthood in a national survey of young Kenyan women. In 2010, we conducted the Violence against Children Survey in Kenya, collecting retrospective reports from 13 to 24 year old males and females (N = 2928). The analysis presented here focused on females aged 18-24 who ever had an intimate partner (n = 566). Read More

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http://dx.doi.org/10.1016/j.chiabu.2018.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139638PMC
October 2018

The time is now: closing the pediatric treatment gap and building resilience among female sex workers and their children.

AIDS 2018 Sep;32(14):1913-1915

Office of HIV/AIDS, U.S. Agency for International Development, Arlington, Virginia. USA.

: Motherhood is common among female sex workers (FSWs) and many have at least one biological child. Preventable mother-to-child transmission of HIV can occur given poor uptake of contraception coupled with high rates of unintended pregnancies among FSWs. Globally, there are 2. Read More

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http://dx.doi.org/10.1097/QAD.0000000000001952DOI Listing
September 2018
10 Reads

Adverse fetal and infant outcomes among HIV-infected women who received either nonnucleoside reverse transcriptase inhibitor-based or protease inhibitor-based antiretroviral therapy for prevention of mother-to-child transmission.

AIDS 2018 Jul;32(12):1625-1632

Division of HIV/AIDS Prevention, U.S. Centers for Disease Control and Prevention.

Background: For HIV-infected pregnant and breastfeeding women, antiretroviral therapy (ART) is known to reduce the mother's risk of passing the infection to her child. However, concerns remain about possible associations between various components of different ART regimens and adverse fetal and infant outcomes. As part of a clinical trial in western Kenya for the prevention of mother-to-child transmission (PMTCT) of HIV, pregnant women received one of two different ART regimens. Read More

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http://Insights.ovid.com/crossref?an=00002030-201807310-0000
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http://dx.doi.org/10.1097/QAD.0000000000001816DOI Listing
July 2018
6 Reads

Trend of HIV/AIDS for the last 26 years and predicting achievement of the 90-90-90 HIV prevention targets by 2020 in Ethiopia: a time series analysis.

BMC Infect Dis 2018 Jul 11;18(1):320. Epub 2018 Jul 11.

Department of Medicine, College of Medicine and Health Sciences, Wolkite University, Wolkite, Ethiopia.

Background: HIV infection continues to be epidemic of public health importance with a prevalence of 1.1% and incidence of 0.33/1000 population having low-intensity mixed epidemic. Read More

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12879-018-3214-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042262PMC
July 2018
30 Reads

Pediatric HIV Treatment Gaps in 7 East and Southern African Countries: Examination of Modeled, Survey, and Routine Program Data.

J Acquir Immune Defic Syndr 2018 Aug;78 Suppl 2:S134-S141

ICAP at Columbia University, New York, NY.

Background: Remarkable success in the prevention and treatment of pediatric HIV infection has been achieved in the past decade. Large differences remain between the estimated number of children living with HIV (CLHIV) and those identified through national HIV programs. We evaluated the number of CLHIV and those on treatment in Lesotho, Malawi, Swaziland, Tanzania, Uganda, Zambia, and Zimbabwe. Read More

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http://dx.doi.org/10.1097/QAI.0000000000001739DOI Listing
August 2018
13 Reads
4.560 Impact Factor

Beyond Early Infant Diagnosis: Changing the Approach to HIV-Exposed Infants.

J Acquir Immune Defic Syndr 2018 Aug;78 Suppl 2:S107-S114

Division of Global HIV and TB (DGHT), Centers for Disease Control and Prevention (CDC), Atlanta, GA.

Despite dramatic global progress with implementing prevention of mother-to-child HIV transmission (PMTCT) programs, there were 160,000 new pediatric HIV infections in 2016. More than 50% of infant HIV infections now occur in the postpartum period, reflecting the relatively high coverage of interventions in the antenatal period and the need for greater attention to the breastfeeding mother and her HIV-exposed infant (HEI). Early diagnosis and treatment are critical to prevent morbidity and mortality in HIV-infected children; however, early infant HIV testing rates remain low in most high HIV-burden countries. Read More

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http://dx.doi.org/10.1097/QAI.0000000000001736DOI Listing
August 2018
4 Reads

Strategies for Identifying and Linking HIV-Infected Infants, Children, and Adolescents to HIV Treatment Services in Resource Limited Settings.

J Acquir Immune Defic Syndr 2018 Aug;78 Suppl 2:S98-S106

U.S. Centers for Disease Control and Prevention (CDC), Division of Global HIV and TB, Atlanta, GA.

Many children living with HIV in resource-limited settings remain undiagnosed and at risk for HIV-related mortality and morbidity. This article describes 5 key strategies for strengthening HIV case finding and linkage to treatment for infants, children, and adolescents. These strategies result from lessons learned during the Accelerating Children's HIV/AIDS Treatment Initiative, a public-private partnership between the President's Emergency Plan for AIDS Relief (PEPFAR) and the Children's Investment Fund Foundation (CIFF). Read More

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http://Insights.ovid.com/crossref?an=00126334-201808152-0000
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http://dx.doi.org/10.1097/QAI.0000000000001732DOI Listing
August 2018
8 Reads

Increasing Prevalence of HIV Pretreatment Drug Resistance in Women But Not Men in Rural Uganda During 2005-2013.

AIDS Patient Care STDS 2018 Jul;32(7):257-264

1 Department of Medicine, Massachusetts General Hospital , Boston, Massachusetts.

The prevalence of HIV pretreatment drug resistance (PDR) is increasing in sub-Saharan Africa. We sought to describe correlates of PDR and evaluate effects of PDR on clinical outcomes in rural Uganda. We analyzed data from the Uganda AIDS Rural Treatment Outcomes study, a cohort of antiretroviral therapy (ART)-naive adults with HIV (2005-2015). Read More

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http://dx.doi.org/10.1089/apc.2018.0020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034395PMC
July 2018
10 Reads

Late presentation to HIV/AIDS care at the Douala general hospital, Cameroon: its associated factors, and consequences.

BMC Infect Dis 2018 Jul 3;18(1):298. Epub 2018 Jul 3.

Douala General Hospital, P.0. Box 4856, Douala, Cameroon.

Background: The introduction of anti-retroviral treatment (ART) has significantly reduced mortality and morbidity associated with HIV/AIDS. While treatment at early stages of the disease is related to a better prognosis, late presentation (LP) to care is harmful to the infected person, the society and is more costly. We aimed to describe late presentation to HIV care, its associated factors and consequences in patients followed up in a tertiary hospital in Cameroon. Read More

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http://dx.doi.org/10.1186/s12879-018-3204-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029364PMC
July 2018
7 Reads

Characteristics associated with lack of HIV testing during pregnancy and delivery in 36 U.S. states, 2004-2013.

Int J STD AIDS 2018 Oct 4;29(12):1225-1233. Epub 2018 Jul 4.

3 Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.

The Centers for Disease Control and Prevention and the American Congress of Obstetricians and Gynecologists recommend universal prenatal HIV testing to prevent perinatal HIV transmission in the U.S.; since the 1990s perinatal HIV transmission has declined. Read More

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http://dx.doi.org/10.1177/0956462418780053DOI Listing
October 2018
9 Reads
1.037 Impact Factor

Early Breastfeeding Cessation Among HIV-Infected and HIV-Uninfected Women in Western Cape Province, South Africa.

AIDS Behav 2018 Jul;22(Suppl 1):114-120

Department of Paediatrics & Child Health, Stellenbosch University, Francie van Zijl Drive, Cape Town, 8000, South Africa.

As part of the Mother-Infant Health Study, we describe infant feeding practices among HIV-infected and HIV-uninfected mothers over a 12-month period when the Western Cape Province prevention of mother-to-child transmission (PMTCT) program was transitioning from a policy of exclusive formula feeding to one of exclusive breastfeeding. Two hundred pairs of mother and HIV-uninfected infant were included in the analysis, among whom 81 women were HIV uninfected and breastfeeding. Of the 119 HIV-infected mothers, 50 (42%) were breastfeeding and 69 (58%) were formula feeding. Read More

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http://dx.doi.org/10.1007/s10461-018-2208-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091631PMC
July 2018
11 Reads

Eliminating Mother-to-Child Transmission of HIV by 2030: 5 Strategies to Ensure Continued Progress.

Glob Health Sci Pract 2018 06 29;6(2):249-256. Epub 2018 Jun 29.

Office of HIV/AIDS, United States Agency for International Development, Washington, DC, USA.

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http://dx.doi.org/10.9745/GHSP-D-17-00097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024627PMC

"Well, not me, but other women do not register because..."- Barriers to seeking antenatal care in the context of prevention of mother-to-child transmission of HIV among Zimbabwean women: a mixed-methods study.

BMC Pregnancy Childbirth 2018 Jun 28;18(1):271. Epub 2018 Jun 28.

Centre for Sexual Health and HIV/AIDS Research (CeSHHAR) Zimbabwe, 9 Monmouth Rd, Avondale West, Harare, Zimbabwe.

Background: While barriers to uptake of antenatal care (ANC) among pregnant women have been explored, much less is known about how integrating prevention of mother-to-child transmission (PMTCT) programmes within ANC services affects uptake. We explored barriers to uptake of integrated ANC services in a poor Zimbabwean community.

Methods: A cross-sectional survey was conducted among post-natal women at Mbare Clinic, Harare, between September 2010 and February 2011. Read More

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http://dx.doi.org/10.1186/s12884-018-1898-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022348PMC
June 2018
4 Reads

Update of Recommendations for Use of Once-Weekly Isoniazid-Rifapentine Regimen to Treat Latent Mycobacterium tuberculosis Infection.

MMWR Morb Mortal Wkly Rep 2018 Jun 29;67(25):723-726. Epub 2018 Jun 29.

Division of Tuberculosis Elimination, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, CDC.

Treatment of latent tuberculosis infection (LTBI) is critical to the control and elimination of tuberculosis disease (TB) in the United States. In 2011, CDC recommended a short-course combination regimen of once-weekly isoniazid and rifapentine for 12 weeks (3HP) by directly observed therapy (DOT) for treatment of LTBI, with limitations for use in children aged <12 years and persons with human immunodeficiency virus (HIV) infection (1). CDC identified the use of 3HP in those populations, as well as self-administration of the 3HP regimen, as areas to address in updated recommendations. Read More

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http://www.cdc.gov/mmwr/volumes/67/wr/mm6725a5.htm?s_cid=mm6
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http://dx.doi.org/10.15585/mmwr.mm6725a5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023184PMC
June 2018
16 Reads

Prevention of Hepatitis B Virus Infection in the United States: Recommendations of the Advisory Committee on Immunization Practices.

MMWR Recomm Rep 2018 01 12;67(1):1-31. Epub 2018 Jan 12.

Division of Viral Hepatitis, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, CDC.

HEPATITIS B VIRUS (HBV) IS TRANSMITTED VIA BLOOD OR SEXUAL CONTACT. PERSONS WITH CHRONIC HBV INFECTION ARE AT INCREASED RISK FOR CIRRHOSIS AND LIVER CANCER AND REQUIRE MEDICAL CARE. THIS REPORT UPDATES AND SUMMARIZES PREVIOUSLY PUBLISHED RECOMMENDATIONS FROM THE ADVISORY COMMITTEE ON IMMUNIZATION PRACTICES (ACIP) AND CDC REGARDING THE PREVENTION OF HBV INFECTION IN THE UNITED STATES. Read More

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http://dx.doi.org/10.15585/mmwr.rr6701a1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837403PMC
January 2018
4 Reads