8,138 results match your criteria Journal of Groups in Addiction & Recovery [Journal]


Neuropsychiatric symptoms in Tanzanian HIV-infected children receiving long-term efavirenz treatment: a multicentre, cross-sectional, observational study.

Lancet HIV 2019 Feb 12. Epub 2019 Feb 12.

Department of Paediatrics, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.

Background: Efavirenz is commonly prescribed for children with HIV infection, yet little is known about risks of neuropsychiatric side-effects. We aimed to compare competence (social involvement, activities, and school performance) and psychopathology (internalising and externalising problems), cognitive performance (intelligence and working memory), and adherence in Tanzanian children on an efavirenz-based versus a non-efavirenz-based regimen.

Methods: In this multicentre, cross-sectional, observational study, we included consecutive children (aged 6-12 years) with HIV infection, on combination antiretroviral therapy (cART) for at least 6 months, and with viral loads of less than 1000 copies per mL from HIV care clinics of three primary health facilities and three referral hospitals in Moshi, Kilimanjaro, Tanzania. Read More

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http://dx.doi.org/10.1016/S2352-3018(18)30329-1DOI Listing
February 2019

Quality of life and psychological dysfunction in traumatized and nontraumatized patients with psychogenic nonepileptic seizures (PNES).

Epilepsy Behav 2019 Feb 12;92:341-344. Epub 2019 Feb 12.

CAPHRI School for Public Health and Primary Care, Department of Health Services Research, Maastricht University, Maastricht, the Netherlands; Centre for Economic Evaluation, Trimbos Institute, Netherlands Institute of Mental Health and Addiction, Utrecht, the Netherlands.

Objectives: Psychogenic nonepileptic seizures (PNES) have the appearance of epileptic seizures, yet show no epileptiform discharges in the brain. The quality of life (QOL) in patients with PNES is reportedly low and trauma eems to be a relevant risk factor. The objective of this study was to examine the difference between measures of (epilepsy-specific) QOL (Quality of Life in Epilepsy Inventory; QOLIE-31p) and psychological dysfunction (trauma symptom inventory; TSI) between patients with diagnosed PNES with self-reported trauma and those without self-reported trauma. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15255050183095
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http://dx.doi.org/10.1016/j.yebeh.2019.01.024DOI Listing
February 2019
5 Reads

Theta-gamma Coupling in the Prelimbic Area is Associated with Heroin Addiction.

Neurosci Lett 2019 Feb 12. Epub 2019 Feb 12.

Department of Psychology & key Laboratory of Psychological Assessment and Rehabilitation for Exceptional Children, Lingnan Normal University, Zhanjiang 524048, China. Electronic address:

The medial prefrontal cortex (mPFC) is implicated in the regulation of drug-seeking behavior, but the specific contributions of the mPFC prelimbic (PL) subdivision and the precise mechanisms underlying heroin abuse remain largely unclear. In the present study, we examined changes in the rhythmic ensemble activity of PL neurons after induction of heroin addiction in rats. Rats were injected daily with saline (control group) or heroin (addiction group) in the light chamber of a light-dark shuttle box, and a video tracking system was used to measure conditioned place preference (CPP) as a sign of addiction. Read More

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http://dx.doi.org/10.1016/j.neulet.2019.02.020DOI Listing
February 2019

Deficient Functioning of Fronto-Striatal Circuits During the Resolution of Cognitive Conflict in Cannabis-Using Youth.

J Am Acad Child Adolesc Psychiatry 2018 Oct 30. Epub 2018 Oct 30.

New York State Psychiatric Institute and the Department of Psychiatry, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY.

Objective: Disturbances in self-regulatory control are involved in the initiation and maintenance of addiction, including cannabis use disorder (CUD). In adults, chronic cannabis use is associated with disturbances in fronto-striatal circuits during tasks that require the engagement of self-regulatory control, including the resolution of cognitive conflict. Understudied are the behavioral and neural correlates of these processes earlier in the course of cannabis use, disentangled from effects of long-term use. Read More

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http://dx.doi.org/10.1016/j.jaac.2018.09.436DOI Listing
October 2018

The Effect of the Irreversible Inequality on Pro-social Behaviors of People With Disabilities.

Front Psychol 2019 31;10:12. Epub 2019 Jan 31.

Department and Institute of Psychology, Ningbo University, Ningbo, China.

Inequalities have always been central to psychology, sociology and related fields such as social policy, gender studies, critical race studies, and human geography. Although inequality affects pro-social behaviors, there are still some controversies over this issue among people with disabilities. The current study aimed to investigate pro-social behaviors of people with disabilities and the effect of the irreversible inequality on pro-social behaviors. Read More

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http://dx.doi.org/10.3389/fpsyg.2019.00012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366110PMC
January 2019

Passion for Exercise: Passion's Relationship to General Fitness Indicators and Exercise Addiction.

Int J Exerc Sci 2019 1;12(5):122-135. Epub 2019 Jan 1.

School of Kinesiology, Ball State University, Muncie, IN, USA.

Research into the Dualistic Model of Passion (DMP) has suggested that a harmonious passion for an activity is related to more positive outcomes (e.g., higher well-being and satisfaction with life), and an obsessive passion for an activity is related to negative and less adaptive outcomes (e. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355203PMC
January 2019

Sub-dimensions of Alcohol Use Disorder in Alcohol Preferring and Non-preferring Rats, a Comparative Study.

Front Behav Neurosci 2019 30;13. Epub 2019 Jan 30.

Pharmacology Unit, School of Pharmacy, University of Camerino, Camerino, Italy.

Recent animal models of alcohol use disorder (AUD) are centered in capturing individual vulnerability differences in disease progression. Here, we used genetically selected Marchigian Sardinian alcohol-preferring (msP) and Wistars rats to apply a multidimensional model of AUD adapted from a previously described DSM-IV/DSM-5 multisymptomatic cocaine addiction model. As proof of concept, we hypothesized that msP rats, genetically selected for excessive drinking, would be more prone to develop dependence-like behavior compared to Wistars. Read More

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http://dx.doi.org/10.3389/fnbeh.2019.00003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364792PMC
January 2019

Predictors of substance use treatment initiation and engagement among adult and adolescent Medicaid recipients.

Subst Abus 2019 Feb 13:1-7. Epub 2019 Feb 13.

a Center for Health Systems Effectiveness , Oregon Health & Science University , Portland , Oregon , USA.

Background: It is important to understand patterns and predictors of initiation and engagement in treatment for Medicaid-covered individuals with substance use disorders because Medicaid is a major source of payment for addiction treatment in the United States. Our analysis examined similarities and differences in predictors between adults and adolescents.

Methods: An analysis of Oregon Medicaid claims data for the time period January 2010 through June 2015 assessed rates of substance use and of treatment initiation and engagement using the Healthcare Effectiveness Data and Information Set (HEDIS) definitions. Read More

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http://dx.doi.org/10.1080/08897077.2018.1550467DOI Listing
February 2019

"A scarlet letter": Stigma and other factors affecting trust in the health care system for women seeking substance abuse treatment in a community setting.

Subst Abus 2019 Feb 13:1-8. Epub 2019 Feb 13.

c Department of Psychology , Vanderbilt University , Nashville , Tennessee , USA.

Background: Trust in health care has been shown to influence health care utilization, perceptions of fair treatment, and health outcomes in the general population. The literature on trust in health care in individuals with a history of substance use disorder (SUD) is more limited, primarily examining the patient-provider relationship. Women seeking substance abuse treatment in community-based programs have higher rates of prior trauma and health disparities compared with male counterparts and the general population. Read More

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http://dx.doi.org/10.1080/08897077.2018.1544184DOI Listing
February 2019

Impact of menthol on oral nicotine consumption in female and male Sprague Dawley rats.

Nicotine Tob Res 2019 Feb 11. Epub 2019 Feb 11.

Department of Pharmacology, Faculty of Medicine, Uludag University, Bursa, Turkey.

Introduction: One of the most preferable flavors in oral nicotine delivery systems is menthol which masks the harshness of tobacco. However, possible interactions between oral menthol and nicotine on intake and preference remain unclear. Therefore, we aimed to determine the impact of menthol on oral nicotine consumption. Read More

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http://dx.doi.org/10.1093/ntr/ntz019DOI Listing
February 2019
1 Read

Long-term effectiveness of a gambling intervention program among children in central Illinois.

PLoS One 2019 11;14(2):e0212087. Epub 2019 Feb 11.

Center for Outcomes Research, Department of Medicine, University of Illinois College of Medicine at Peoria, Peoria, IL, United States of America.

Youth gambling is an increasing concern. As a response, the "Don't Gamble Away our Future (DGAOF)" program has been implemented among children in central Illinois. We aim to assess the long-term effectiveness of this school-based youth gambling prevention program in Illinois using the data from 2005 to 2009. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212087PLOS
February 2019

Examining the Link Between Cardiovascular Risk Factors and Neuropsychiatric Symptoms in Mild Cognitive Impairment and Major Depressive Disorder in Remission.

J Alzheimers Dis 2019 Feb 2. Epub 2019 Feb 2.

Department of Psychiatry, University of Toronto, Toronto, Canada.

Background: Cardiovascular risk factors (CVRFs) have been linked to both depression and cognitive decline but their role in neuropsychiatric symptoms (NPS) has yet to be clarified.

Objective: Understanding the role of CVRFs in the etiology of NPS for prospective treatments and preventive strategies to minimize these symptoms.

Methods: We examined the distribution of NPS using the Neuropsychiatric Inventory (NPI) scores in three cohorts from the Prevention of Alzheimer's Dementia with Cognitive Remediation Plus Transcranial Direct Current Stimulation in Mild Cognitive Impairment and Depression (PACt-MD) study: older patients with a lifetime history of major depressive disorder (MDD) in remission, patients with mild cognitive impairment (MCI), and patients with combined MCI and MDD. Read More

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https://www.medra.org/servlet/aliasResolver?alias=iospress&a
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http://dx.doi.org/10.3233/JAD-181099DOI Listing
February 2019
8 Reads

Limonene Inhibits Methamphetamine-Induced Sensitizations via the Regulation of Dopamine Receptor Supersensitivity.

Biomol Ther (Seoul) 2019 Feb 8. Epub 2019 Feb 8.

College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea.

Limonene is a cyclic terpene found in citrus essential oils and inhibits methamphetamine- induced locomotor activity. Drug dependence is a severe neuropsychiatric condition that depends in part on changes in neurotransmission and neuroadaptation, induced by exposure to recreational drugs such as morphine and methamphetamine. In this study, we investigated the effects of limonene on the psychological dependence induced by drug abuse. Read More

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http://dx.doi.org/10.4062/biomolther.2018.213DOI Listing
February 2019
1 Read

Ghrelin: From a gut hormone to a potential therapeutic target for alcohol use disorder.

Physiol Behav 2019 Feb 7;204:49-57. Epub 2019 Feb 7.

Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology, National Institute on Alcohol Abuse and Alcoholism Division of Intramural Clinical and Biological Research and National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Bethesda, MD, USA; Center on Compulsive Behaviors, National Institutes of Health, Bethesda, MD, USA; Medication Development Program, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, MD, USA; Center for Alcohol and Addiction Studies, Department of Behavioral and Social Sciences, Brown University, Providence, RI, USA. Electronic address:

Alcohol use disorder (AUD) is a leading cause of morbidity and mortality worldwide. However, treatment options, including pharmacotherapies, are limited in number and efficacy. Accumulating evidence suggests that elements of the gut-brain axis, such as neuroendocrine pathways and gut microbiome, are involved in the pathophysiology of AUD and, therefore, may be investigated as potential therapeutic targets. Read More

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http://dx.doi.org/10.1016/j.physbeh.2019.02.008DOI Listing
February 2019
2 Reads

Efficiency of local therapy with the use of a new preparation for oral care at periodontitis in the course of hyperpeptic gastritis after tobacco smoke intoxication.

Wiad Lek 2018 ;71(9):1695-1700

Ukrainian Medical Stomatological Academy, Poltava, Ukraine.

Objective: Introduction: Periodontal diseases, arising against a background of stomach pathology at tobacco addiction remain an acute problem of modern dentistry. The aim of the work is an experimental study of efficiency of application of the new preparation for oral care during treatment of periodontitis simulated against a background of hyperpeptic gastritis under conditions of intoxication by tobacco smoke.

Patients And Methods: Materials and methods: At the first stage all experimental animals were divided into 4 groups: І - intact, II - with simulated periodontitis, III - with simulated periodontitis against a background of simulated hyperpeptic gastritis, IV - with simulated periodontitis against a background of hyperpeptic gastritis under conditions of tobacco smoking. Read More

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January 2018
1 Read

Assessing drug cue-induced brain response in heroin dependents treated by methadone maintenance and protracted abstinence measures.

Brain Imaging Behav 2019 Feb 8. Epub 2019 Feb 8.

Department of Radiology, Tangdu Hospital, The Fourth Military Medical University, 569 Xinsi Road, BaQiao District, Xi'an, 710038, Shaanxi, China.

Methadone maintenance treatment (MMT) and protracted abstinence (PA) are common methods of therapy in heroin addiction as both suppress the craving for drug use. However, the difference in patterns of brain function between two groups is unknown. Functional magnetic resonance imaging (fMRI) based drug cue-reactivity task is a good tool to understand the change of brain function during a certain period of treatment. Read More

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http://dx.doi.org/10.1007/s11682-019-00051-5DOI Listing
February 2019
1 Read
3.385 Impact Factor

Emotion Perception in Members of Norwegian Mensa.

Authors:
Jens Egeland

Front Psychol 2019 23;10:27. Epub 2019 Jan 23.

Vestfold Hospital Trust, Division of Mental Health and Addiction, Department of Psychology, University of Oslo, Oslo, Norway.

Are people with superior intelligence also superior in interpreting the emotions of others? Some studies find that an underlying g-factor links all mental processes leading to an expectation of a positive answer to the question, while other studies find that there is a cost to giftedness. No previous study have tested social cognition among highly gifted, or the Mensa society specifically. The study measures emotion recognition in 63 members of the Norwegian Mensa and 101 community controls. Read More

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http://dx.doi.org/10.3389/fpsyg.2019.00027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351459PMC
January 2019
3 Reads

Dentate gyrus μ-opioid receptor-mediated neurogenic processes are associated with alterations in morphine self-administration.

Sci Rep 2019 Feb 6;9(1):1471. Epub 2019 Feb 6.

Department of Neurobiology, School of Basic Medical Sciences, Key Laboratory for Neuroscience of the Ministry of Education and National Health and Family Planning Commission, Neuroscience Research Institute, Peking University, 38 Xueyuan Road, Beijing, 100191, China.

Adult hippocampal dentate gyrus (DG) neural stem cells (NSCs) continuously undergo proliferation and differentiation, producing new functional neurons that remodel existing synaptic circuits. Although proliferation of these adult DG NSCs has been implicated in opiate dependence, whether NSC neuronal differentiation and subsequent dendritogenesis are also involved in such addictive behavior remains unknown. Here, we ask whether opiate exposure alters differentiation and dendritogenesis of DG NSCs and investigate the possibility that these alterations contribute to opiate addiction. Read More

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http://dx.doi.org/10.1038/s41598-018-37083-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365505PMC
February 2019

Hospitalization of children after prenatal exposure to opioid maintenance therapy during pregnancy: a national registry study from the Czech Republic.

Addiction 2019 Feb 6. Epub 2019 Feb 6.

Department of Addictology, First Faculty of Medicine, Charles University in Prague, Czech Republic.

Background And Aims: Our understanding of the long-term safety of prenatal exposure to Opioid Maintenance Treatment (OMT) is insufficient. We compared childhood morbidity (0-3 years) between OMT-exposed and relevant comparison groups.

Design: Nation-wide, registry-based cohort study. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/add.14576
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http://dx.doi.org/10.1111/add.14576DOI Listing
February 2019
3 Reads

Investigation of protective effects of coenzyme Q10 on impaired synaptic plasticity in a male rat model of Alzheimer's disease.

Brain Res Bull 2019 Feb 2;147:14-21. Epub 2019 Feb 2.

Anatomy Department, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.

Oxidative stress plays a key role in contributing to β-amyloid (Aβ) deposition in Alzheimer's disease (AD). Coenzyme Q10 (Q10) is a powerful antioxidant that buffers the potential adverse consequences of free radicals. In this study, we investigated the neuroprotective effects of Q10 on Aβ-induced impairment in hippocampal long-term potentiation (LTP), a widely researched model of synaptic plasticity, which occurs during learning and memory, in a rat model of AD. Read More

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http://dx.doi.org/10.1016/j.brainresbull.2019.01.025DOI Listing
February 2019
3 Reads

Effects of familial risk and stimulant drug use on the anticipation of monetary reward: an fMRI study.

Transl Psychiatry 2019 Feb 4;9(1):65. Epub 2019 Feb 4.

Departments of Psychiatry and Psychology, University of Cambridge, Cambridge, UK.

The association between stimulant drug use and aberrant reward processing is well-documented in the literature, but the nature of these abnormalities remains elusive. The present study aims to disentangle the separate and interacting effects of stimulant drug use and pre-existing familial risk on abnormal reward processing associated with stimulant drug addiction. We used the Monetary Incentive Delay task, a well-validated measure of reward processing, during fMRI scanning in four distinct groups: individuals with familial risk who were either stimulant drug-dependent (N = 41) or had never used stimulant drugs (N = 46); and individuals without familial risk who were either using stimulant drugs (N = 25) or not (N = 48). Read More

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http://dx.doi.org/10.1038/s41398-019-0399-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362203PMC
February 2019

Structural neuroimaging correlates of social deficits are similar in autism spectrum disorder and attention-deficit/hyperactivity disorder: analysis from the POND Network.

Transl Psychiatry 2019 Feb 4;9(1):72. Epub 2019 Feb 4.

Department of Paediatrics, University of Toronto, Toronto, ON, Canada.

Autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder (ADHD), and obsessive-compulsive disorder (OCD) have been associated with difficulties recognizing and responding to social cues. Neuroimaging studies have begun to map the social brain; however, the specific neural substrates contributing to social deficits in neurodevelopmental disorders remain unclear. Three hundred and twelve children underwent structural magnetic resonance imaging of the brain (controls = 32, OCD = 44, ADHD = 77, ASD = 159; mean age = 11). Read More

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http://www.nature.com/articles/s41398-019-0382-0
Publisher Site
http://dx.doi.org/10.1038/s41398-019-0382-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361977PMC
February 2019
4 Reads

Exploring mental health professionals' practice in relation to smoke-free policy within a mental health trust: a qualitative study using the COM-B model of behaviour.

BMC Psychiatry 2019 Feb 4;19(1):54. Epub 2019 Feb 4.

Department of Behavioural Science and Health, University College London, 1-19 Torrington Place, London, WC1E 6BT, UK.

Background: Smoking has played a significant role in the historical culture of mental healthcare settings. Mental health professionals (MHPs) often hold dismissive attitudes regarding the importance of smoking cessation in the context of mental healthcare. In 2007, English mental health inpatient buildings were required by law to become smoke-free, and healthcare trusts have more recently begun to implement comprehensive policies (i. Read More

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http://dx.doi.org/10.1186/s12888-019-2029-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360690PMC
February 2019
1 Read

Greater empathy in MDMA users.

J Psychopharmacol 2019 Feb 5:269881119826594. Epub 2019 Feb 5.

1 Psychopharmacology and Addiction Research Centre (PARC), University of Exeter, Exeter, UK.

Background:: 3,4-Methylenedioxymethamphetamine (MDMA) is widely known for its positive acute effects on social behaviour, such as increasing empathy, whilst also attenuating the negative impact of social exclusion. However there is a scarcity of research that investigates the long-term impact of recreational MDMA use on these fundamental social processes.

Method:: Sixty-seven individuals were split into three groups based on their drug-use history: poly-drug MDMA users ( n = 25), poly-drug users who do not use MDMA ( n = 19), alcohol-only users ( n = 23), and were tested in an independent groups design. Read More

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http://dx.doi.org/10.1177/0269881119826594DOI Listing
February 2019

The effect of inhalation aromatherapy with rose essential oil on the anxiety of patients undergoing coronary artery bypass graft surgery.

Complement Ther Clin Pract 2019 Feb 1;34:201-207. Epub 2018 Dec 1.

Orthopedic Research Center, Mazandaran University of Medical Sciences, Sari, Iran. Electronic address:

Background And Purpose: Anxiety is one of the most common responses of patients awaiting coronary artery bypass graft (CABG) surgery to stressful conditions before surgery. This study is intended to examine the effect of inhalation aromatherapy with rose essential oil on the anxiety of patients undergoing CABG surgery.

Materials And Methods: This was a single-blind randomized clinical trial of 66 patients undergoing CABG surgery. Read More

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http://dx.doi.org/10.1016/j.ctcp.2018.11.014DOI Listing
February 2019
1 Read

An open-label randomized trial of intramuscular olanzapine versus oral clonidine for symptomatic treatment of opioid withdrawal in the emergency department.

Clin Toxicol (Phila) 2019 Feb 4:1-6. Epub 2019 Feb 4.

a Department of Emergency Medicine , Hennepin County Medical Center , Minneapolis , MN , USA.

Background: Patients with opioid withdrawal often present to the Emergency Department (ED), but many EDs do not have the infrastructure in place to initiate treatment with opioid agonists (methadone or buprenorphine). Therefore, ED management often entails symptomatic control. The purpose of this study was to compare olanzapine to clonidine for the treatment of opioid withdrawal symptoms. Read More

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http://dx.doi.org/10.1080/15563650.2018.1547828DOI Listing
February 2019

Clinical efficacy of trauma-focused psychotherapies in treatment-resistant depression (TRD) in-patients: A randomized, controlled pilot-study.

Psychiatry Res 2019 Jan 24;273:567-574. Epub 2019 Jan 24.

Psychiatric Hospital "Villa Santa Chiara", Verona, Italy.

In major depressive disorder (MDD) patients, life stress events represent a risk factor for a severe, early-onset, treatment-resistant and chronic endophenotype. Treatment-resistant depression (TRD) patients who have experienced traumatic events could benefit from evidence-based trauma-focused psychotherapies. Because this topic has never been investigated, the aim of this pilot trial was to evaluate whether trauma-focused cognitive-behavioural therapy (TF-CBT) and/or eye movement desensitization and reprocessing (EMDR) can help achieve depressive symptom remission in TRD patients. Read More

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http://dx.doi.org/10.1016/j.psychres.2019.01.070DOI Listing
January 2019

Borderline Intellectual Functioning and Lifetime Duration of Homelessness among Homeless Adults with Mental Illness.

Healthc Policy 2018 Nov;14(2):40-46

Centre for Addiction and Mental Health, Centre for Urban Health Solutions, St. Michael's Hospital, Department of Psychiatry, University of Toronto, Toronto, ON.

This paper reports on the association between intellectual functioning and lifetime homelessness duration among 172 homeless adults with mental illness in Toronto, Canada. Using a standardized test of intellectual functioning, we created two groups: individuals with borderline or lower intellectual functioning (16%) and individuals with above borderline intellectual functioning (84%). Lifetime homelessness duration was approximately three years longer, or almost twice as long, for individuals with borderline or lower intellectual functioning. Read More

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http://dx.doi.org/10.12927/hcpol.2018.25687DOI Listing
November 2018

Loneliness among adults with visual impairment: prevalence, associated factors, and relationship to life satisfaction.

Health Qual Life Outcomes 2019 Feb 1;17(1):24. Epub 2019 Feb 1.

Section for Trauma, Catastrophes and Forced Migration - Adults and Elderly, Norwegian Centre for Violence and Traumatic Stress Studies, PB 181 Nydalen, Oslo, Norway.

Background: Little is known about whether and to what extent loneliness impacts the lives of people with visual impairment (VI). Thus, the aim of this study was to examine the prevalence of and factors associated with loneliness in adults with VI, and to examine its association with life satisfaction.

Methods: This cross-sectional interview study included a probability sample of 736 adults (≥18 years old) with VI who were members of the Norwegian Association of the Blind and Partially Sighted. Read More

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http://dx.doi.org/10.1186/s12955-019-1096-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359849PMC
February 2019

Serotonin transporter gene linked polymorphism (5-HTTLPR) determines progredience of alcohol dependence in Belarusian young males.

Adv Med Sci 2019 Jan 28;64(1):169-173. Epub 2019 Jan 28.

Department of Psychiatry, Medical University of Bialystok, Choroszcz, Poland. Electronic address:

Purpose: Allelic duality and functional impact of degenerate repeat at 5'- flanking promoter region in SLC6A4 gene of the serotonin transporter (5-HTTLPR), have been in the focus of investigations over the years. Various outcomes regarding an association of its polymorphism with risks of alcohol dependence syndrome (ADS) were presented. Such studies have not been conducted in the Eastern European population e. Read More

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http://dx.doi.org/10.1016/j.advms.2018.08.010DOI Listing
January 2019
1 Read

Biochemical Analysis and Association of Butyrylcholinesterase SNPs rs3495 and rs1803274 with Substance Abuse Disorder.

J Mol Neurosci 2019 Feb 1. Epub 2019 Feb 1.

Department of Biosciences, Functional Proteomics and Genomics Lab, COMSATS University Islamabad, Islamabad, Pakistan.

Addiction is a complex mental and behavioral disorder that changes the neurochemistry and physiology of the brain. Genetics also plays a significant role in the pathophysiology of addiction. Butyrylcholinesterase (BChE), a cholinergic enzyme, has been implicated in the metabolism of various drugs, including cocaine, and an association between single-nucleotide polymorphisms (SNPs) of the butyrylcholinesterase gene (BCHE) and neuronal disorders has been reported. Read More

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http://dx.doi.org/10.1007/s12031-018-1251-7DOI Listing
February 2019

A new Classification System for describing concurrent use of Nicotine Vaping Products alongside Cigarettes (so-called "Dual Use"): Findings from the ITC-4 Country Smoking and Vaping Wave 1 Survey t.

Addiction 2019 Jan 31. Epub 2019 Jan 31.

Medical University of South Carolina, USA.

Aims: To determine whether a simple combination of level of smoking and level of vaping results in a useful typology for characterising smoking and vaping behaviours.

Methods: Cross-sectional data from adults (≥18 years) in the 2016 Wave 1 ITC Four Country Smoking and Vaping Survey in the United States (n=2291), England (n=3591), Australia (n=1376), and Canada (n=2784) were used. Participants who either smoked, vaped or concurrently used both at least monthly were included and divided into 8 groups based on use frequency of each product (daily, non-daily, no current use). Read More

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http://dx.doi.org/10.1111/add.14570DOI Listing
January 2019
1 Read

Effects of Electroacupuncture on Expression of D1 Receptor (D1R), Phosphorylation of Extracellular-Regulated Protein Kinase 1/2 (p-ERK1/2), and c-Fos in the Insular Cortex of Ketamine-Addicted Rats.

Med Sci Monit Basic Res 2019 Jan 31;25:26-32. Epub 2019 Jan 31.

Department of Anatomy, Wannan Medical College, Wuhu, Anhui, China (mainland).

BACKGROUND The aim of this study was to investigate the effects of electroacupuncture (EA) on expression of the D1 receptor (D1R), phosphorylation of extracellular-regulated protein kinase 1/2 (p-ERK1/2) and c-Fos in the insular cortex (IC) of ketamine-addicted rats. MATERIAL AND METHODS Sprague-Dawley rats were randomly divided into 7 groups: the normal group, the normal saline (NS) group, the ketamine (Ket) group, the U0126+Ket group, the SCH23390+Ket group, the Ket+acupoints EA (EA1) group, and the Ket+ non-acupoints EA (EA2) group. We used immunohistochemistry to detect the expression of D1R, p-ERK1/2, and c-Fos. Read More

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http://dx.doi.org/10.12659/MSMBR.913285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369650PMC
January 2019

Chronic Addiction to Tramadol and Withdrawal Effect on the Spermatogenesis and Testicular Tissues in Adult Male Albino Rats.

Pharmacology 2019 Jan 30;103(3-4):202-211. Epub 2019 Jan 30.

Department of Biology, College of Science, Majmaah University, Majmaah, Al-Zulfi, Saudi Arabia.

Aim: The present study aimed to elucidate the effects of tramadol on the testicular functions of adult male rats due to the chronic usage of tramadol and the effect of its withdrawal.

Method: Adult male albino rats were classified into the following 3 groups: (I) a control administered with normal saline and (II) tramadol-treated rats (40 mg/kg b.w. Read More

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http://dx.doi.org/10.1159/000496424DOI Listing
January 2019

Advancing implementation frameworks with a mixed methods case study in child behavioral health.

Transl Behav Med 2019 Jan 30. Epub 2019 Jan 30.

Centre for Addiction and Mental Health, Toronto, Canada.

Despite a growing policy push for the provision of services based on evidence, evidence-based treatments for children and youth with mental health challenges have poor uptake, yielding limited benefit. With a view to improving implementation in child behavioral health, we investigated a complementary implementation approach informed by three implementation frameworks in the context of implementing motivational interviewing in four child and youth behavioral health agencies: the Active Implementation Frameworks (AIF) (process), the Consolidated Framework for Implementation Research (factors), and the Implementation Outcomes Framework (evaluation). The study design was mixed methods with embedded interrupted time series and motivational interviewing (MI) fidelity was the primary outcome. Read More

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http://dx.doi.org/10.1093/tbm/ibz005DOI Listing
January 2019
1 Read

Improvement of Inter-Professional Collaborative Work Abilities in Mexican Medical and Nursing Students: A Longitudinal Study.

Front Psychol 2019 15;10. Epub 2019 Jan 15.

Center for Biomedical Research of La Rioja (CIBIR), Logroño, Spain.

Inter-professional and interpersonal relationships in collaborative work environments can prove to be critical elements in healthcare practice. When implementers fail to understand the importance of a collaborative perspective, this can lead to communication problems which ultimately harm the users. To improve the inter-professional collaborative work skills of Mexican students in their first year of medical and nursing degrees through the use of a training program geared toward development of interpersonal skills and interdisciplinary work. Read More

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http://dx.doi.org/10.3389/fpsyg.2019.00005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340986PMC
January 2019

Deep Brain Stimulation rescues memory and synaptic activity in a rat model of global ischemia.

J Neurosci 2019 Jan 29. Epub 2019 Jan 29.

Krembil Research Institute, Toronto Western Hospital, University Health Network, 60 Leonard Avenue, Toronto, ON, M5T 2S8, Canada

Ischaemic stroke is responsible for a large number of neurological deficits including memory impairment. Deep brain stimulation (DBS), a well-established therapeutic modality for the treatment of movement disorders, has recently shown potential beneficial effects on memory in animals and Alzheimer's disease patients. Here, we test DBS for its ability to improve memory impairments by stimulating the entorhinal cortex (EC) in a rat model of global ischemia (GI). Read More

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http://www.jneurosci.org/lookup/doi/10.1523/JNEUROSCI.1222-1
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http://dx.doi.org/10.1523/JNEUROSCI.1222-18.2019DOI Listing
January 2019
3 Reads
6.344 Impact Factor

Parental morphine exposure enhances morphine (but not methamphetamine) preference and increases monoamine oxidase-B level in the nucleus accumbens.

Behav Pharmacol 2019 Jan 28. Epub 2019 Jan 28.

Iranian National Center for Addiction Studies.

Opioid addiction is one of the most crucial issues in the world. Opioid abuse by parents makes children more prone to many psychological disorders such as drug addiction. Therefore, this study was carried out to examine the effect of morphine exposure 10 days before gestation on morphine and methamphetamine preference in male offspring. Read More

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http://dx.doi.org/10.1097/FBP.0000000000000465DOI Listing
January 2019
1 Read

Clinical presentations, social functioning, and treatment receipt among individuals with comorbid lifetime PTSD and alcohol use disorders versus drug use disorders: Findings from NESARC-III.

Addiction 2019 Jan 29. Epub 2019 Jan 29.

Department of Psychiatry & Behavioral Sciences, University of Washington, Seattle, Washington.

Aims: To compare individuals with comorbid lifetime Posttraumatic Stress Disorder (PTSD) and alcohol use disorders (AUD; i.e., no drug use disorders [DUD]) with to those with comorbid PTSD and DUD on past-year prevalence of these disorders, social functioning, lifetime psychiatric comorbidities, and treatment receipt. Read More

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http://doi.wiley.com/10.1111/add.14565
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http://dx.doi.org/10.1111/add.14565DOI Listing
January 2019
5 Reads

White matter microstructure in schizophrenia patients with a history of violence.

Eur Arch Psychiatry Clin Neurosci 2019 Jan 29. Epub 2019 Jan 29.

NORMENT, KG Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital, Nydalen, P.O. Box 4956, 0424, Oslo, Norway.

Schizophrenia (SCZ) is associated with increased risk of violence compared to the general population. Neuroimaging research suggests SCZ to be a disorder of disrupted connectivity, with diffusion tensor imaging (DTI) indicating white matter (WM) abnormalities. It has been hypothesized that SCZ patients with a history of violence (SCZ-V) have brain abnormalities distinguishing them from SCZ patients with no history of violence (SCZ-NV). Read More

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http://link.springer.com/10.1007/s00406-019-00988-0
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http://dx.doi.org/10.1007/s00406-019-00988-0DOI Listing
January 2019
2 Reads

Effectiveness of a self-management training for patients with chronic and treatment resistant anxiety or depressive disorders on quality of life, symptoms, and empowerment: results of a randomized controlled trial.

BMC Psychiatry 2019 Jan 28;19(1):46. Epub 2019 Jan 28.

Behavioural Science Institute, Radboud University Medical Center, PO Box 9104, 6500, HE, Nijmegen, The Netherlands.

Background: Anxiety and depressive disorders are common mental disorders. A substantial part of patients does not achieve symptomatic remission after treatment in specialized services. Current care as usual (CAU) for these patients consists of long-term supportive contacts. Read More

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https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12
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http://dx.doi.org/10.1186/s12888-019-2013-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348638PMC
January 2019
3 Reads

Perceived need and availability of psychosocial interventions across buprenorphine prescriber specialties.

Addict Behav 2019 Jan 16;93:72-77. Epub 2019 Jan 16.

University of Kentucky, Department of Behavioral Science and Center on Drug and Alcohol Research, 845 Angliana Avenue, Lexington, KY 40508, United States.

Introduction: Psychosocial interventions are often recommended as part of buprenorphine treatment for patients with opioid use disorder, but little is known about prescriber perspectives on their use and how this varies across buprenorphine prescriber specialties.

Methods: A large US sample of physicians actively prescribing buprenorphine (n = 1174) was surveyed from July 2014 to January 2017. Analyses examined prescriber characteristics and their perceptions and use of psychosocial interventions across three groups of physicians: primary care providers (PCPs), addiction physicians/psychiatrists, and other physicians. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03064603183115
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http://dx.doi.org/10.1016/j.addbeh.2019.01.023DOI Listing
January 2019
2 Reads

Taking a Stand: An Untapped Strategy to Reduce Waterpipe Smoking in Adolescents.

Subst Use Misuse 2019 Jan 26:1-11. Epub 2019 Jan 26.

b Department of Public Health and Clinical Medicine, Unit of Epidemiology and Global Health , Umeå University , Umeå , Sweden.

Introduction: Waterpipe use amongst adolescents is on the rise globally. Thus, there is a need to understand adolescents 'attitudes towards and perceptions of waterpipe use in order to develop specific interventions against this form of tobacco use.

Methods: Focus group interviews were conducted among 37 Swedish adolescents (14 boys and 23 girls) from grades 10 to 12. Read More

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https://www.tandfonline.com/doi/full/10.1080/10826084.2018.1
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http://dx.doi.org/10.1080/10826084.2018.1521429DOI Listing
January 2019
2 Reads

[Profile of first year secondary school children involved in the anti-smoking prevention trial "PEPITES"].

Rev Epidemiol Sante Publique 2019 Jan 24. Epub 2019 Jan 24.

Fondation JDB, 2-4, rue du Mont-Louvet, 91640 Fontenay-Lès-Briis, France.

Background: Many programs which aim to reduce tobacco consumption in young people are carried out in the school environment, addressing a "captive audience" and monitoring the actions over a period of several years. The approaches identified as promising involve putting in place a tobacco prevention program throughout the entire school years incorporated in the school program. Several studies showed that early initiation to psychoactive substances is a strong predictor of addiction. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03987620193000
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http://dx.doi.org/10.1016/j.respe.2018.11.018DOI Listing
January 2019
1 Read

Low-dose augmentation with buprenorphine increases emotional reactivity but not reward activity in treatment resistant mid- and late-life depression.

Neuroimage Clin 2019 Jan 22;21:101679. Epub 2019 Jan 22.

Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address:

Buprenorphine is currently being studied for treatment-resistant depression because of its rapid effect, relative safety, and unique pharmacodynamics. To understand the neural impact of buprenorphine in depression, we examined acute limbic and reward circuit changes during an intervention with low-dose buprenorphine augmentation pharmacotherapy. Mid and late-life adults with major depression (N = 31) who did not completely respond to an adequate trial of venlafaxine were randomized to augmentation with low-dose buprenorphine or matching placebo. Read More

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http://dx.doi.org/10.1016/j.nicl.2019.101679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356006PMC
January 2019
3 Reads

Alterations in body mass index and waist-to-hip ratio in never and minimally treated patients with psychosis: A systematic review and meta-analysis.

Schizophr Res 2019 Jan 23. Epub 2019 Jan 23.

Multimodal Imaging Group, Research Imaging Centre, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Geriatric Mental Health Division, CAMH, University of Toronto, Toronto, Ontario, Canada; Campbell Family Mental Health Research Institute, CAMH, University of Toronto, Toronto, Ontario, Canada. Electronic address:

Background: Obesity is up to 4 times higher in patients with schizophrenia than in the general population. However, the link between obesity and schizophrenia in the absence of antipsychotic use is unclear. Therefore, we aimed to examine differences in obesity measures (body mass index (BMI), waist circumference (WC), and waist-to-hip ratio (WHR)) in antipsychotic-naive and minimally treated (up to 2 weeks of lifetime antipsychotic exposure) patients with psychosis compared to healthy controls (HCs). Read More

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http://dx.doi.org/10.1016/j.schres.2019.01.005DOI Listing
January 2019
7 Reads

Structural network integrity of the central executive network is associated with the therapeutic effect of rTMS in treatment resistant depression.

Prog Neuropsychopharmacol Biol Psychiatry 2019 Jan 25;92:217-225. Epub 2019 Jan 25.

Non-Invasive Neurostimulation Therapies (NINET) Laboratory, Department of Psychiatry, University of British Columbia, 2255 Wesbrook Mall, Vancouver, BC V6T 2A1, Canada. Electronic address:

Repetitive transcranial magnetic stimulation (rTMS) is a first-line option for treatment-resistant depression (TRD), but prediction of treatment outcome remains a clinical challenge. The present study aimed to compare structural and functional covariance networks (SCNs and FCNs) between remitters and nonremitters. We determined the predictive capacities of SCNs and FCNs to discriminate the two groups. Read More

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http://dx.doi.org/10.1016/j.pnpbp.2019.01.012DOI Listing
January 2019
1 Read

Estimating Service Needs for Alcohol and Other Drug Users According to a Tiered Framework: The Case of the São Paulo, Brazil, Metropolitan Area.

J Stud Alcohol Drugs Suppl 2019 Jan;Sup 18:87-95

Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.

Objective: The purpose of this study was to estimate the need for population-level services for alcohol and other drug abuse in support of local planning.

Method: Data were drawn from a subsample of 2,942 interviewees from the São Paulo Megacity Study, which evaluated mental health in the general population (18 years and older) of residents in the São Paulo metropolitan area. This population was classified into five hierarchical categories of severity, making it possible to obtain estimates of need for services, combining evaluation criteria regarding drug and alcohol use and general and mental health comorbidities over the last 12 months. Read More

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January 2019
1 Read

Prevalence of awareness, ever-use, and current use of nicotine vaping products (NVPs) among adult current smokers and ex-smokers in 14 countries with differing regulations on sales and marketing of NVPs: Cross-sectional findings from the ITC Project.

Addiction 2019 Jan 25. Epub 2019 Jan 25.

University of Waterloo, Waterloo, Canada.

Aims: This paper presents updated prevalence estimates of awareness, ever-use, and current use of nicotine vaping products (NVPs) from 14 International Tobacco Control Policy Evaluation Project (ITC Project) countries that have varying regulations governing NVP sales and marketing.

Design, Setting, Participants And Measurements: A cross-sectional analysis of adult (≥18 years) current smokers and ex-smokers from 14 countries participating in the ITC Project. Data from the most recent survey questionnaire for each country were included, which spanned the period 2013 to 2017. Read More

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http://doi.wiley.com/10.1111/add.14558
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http://dx.doi.org/10.1111/add.14558DOI Listing
January 2019
3 Reads

What Orthopaedic Surgeons Need to Know: The Basic Science Behind Opioids.

J Am Acad Orthop Surg 2019 Jan 22. Epub 2019 Jan 22.

From the Department of Orthopaedic Surgery and Rehabilitation, University of Texas Medical Branch at Galveston, Galveston, TX (Dr. Hagedorn and Dr. Danilevich), and the Department of Orthopaedic Surgery, McGovern School of Medicine, University of Texas Health Science Center Houston, Houston, TX (Dr. Gary).

On October 26, 2017, US president, Donald J. Trump, declared the opioid epidemic a national public health emergency. This declaration opened the door to government funding for programs geared toward studying and treating opioid addiction; however, part of the responsibility to slow the epidemic falls on physicians. Read More

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http://Insights.ovid.com/crossref?an=00124635-900000000-9942
Publisher Site
http://dx.doi.org/10.5435/JAAOS-D-18-00438DOI Listing
January 2019
2 Reads