1,149 results match your criteria Journal of Gastrointestinal Cancer [Journal]


Esophageal Squamous Cell Carcinoma Metastatic to Umbilicus: a Case Report with Review of Literature.

J Gastrointest Cancer 2018 Dec 14. Epub 2018 Dec 14.

Laboratory Oncology Unit, Dr. B.R.A. Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, 110029, India.

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http://dx.doi.org/10.1007/s12029-018-00185-7DOI Listing
December 2018

Surgery for Locally Advanced GIT Cancers Has Potentially Good Postoperative Outcomes in a Tertiary Hospital.

J Gastrointest Cancer 2018 Dec 14. Epub 2018 Dec 14.

Department of Medical Oncology, South Egypt Cancer Institute, Assiut University, Assiut, Egypt.

Background: Adhesions and infiltration into adjacent tissues are present in about 12% of gastrointestinal (GIT) cancers. These adhesions have high potential risk of malignancy. Free resection margin is a predictor of good survival in such patients. Read More

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http://dx.doi.org/10.1007/s12029-018-0181-5DOI Listing
December 2018

MAEL Cancer-Testis Antigen as a Diagnostic Marker in Primary Stages of Gastric Cancer with Helicobacter pylori Infection.

J Gastrointest Cancer 2018 Nov 28. Epub 2018 Nov 28.

Department of Modern Sciences and Technologies, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Purpose: Gastric cancer (GC) is the third leading cause of cancer related deaths in the world. Cancer testis antigens (CTAs) are involved in tumor progression of various cancers. These markers have not any expression or minimally expression in normal tissues, highlighting them as efficient methods for molecular targeted therapy. Read More

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http://dx.doi.org/10.1007/s12029-018-0183-3DOI Listing
November 2018
1 Read

Clinicopathological Criteria Defining Mucinous Appendiceal Tumors from 2476 Appendectomies: a Single-Center Retrospective Study.

J Gastrointest Cancer 2018 Nov 28. Epub 2018 Nov 28.

Pathology Department, Faculty of Medicine, Beni Suef University, Beni Suef, Egypt.

Objectives: Mucinous appendiceal tumors (MATs) constitute 0.2-0.3% of appendectomies. Read More

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http://link.springer.com/10.1007/s12029-018-0182-4
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http://dx.doi.org/10.1007/s12029-018-0182-4DOI Listing
November 2018
3 Reads

Anorectal Cancer in Crohn's Disease Has a Poor Prognosis Due to its Advanced Stage and Aggressive Histological Features: a Systematic Literature Review of Japanese Patients.

J Gastrointest Cancer 2018 Nov 26. Epub 2018 Nov 26.

Department of Surgery, Nara Medical University, Kashihara, Nara, Japan.

Background: Patients with Crohn's disease (CD) are generally known to be at an increased risk of cancer. The anorectal area is the most frequent cancer site in Japanese CD patients. However, the risks are not well defined. Read More

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http://dx.doi.org/10.1007/s12029-018-0180-6DOI Listing
November 2018
4 Reads

Pancreatic Cancer and Immunotherapy: Resistance Mechanisms and Proposed Solutions.

J Gastrointest Cancer 2018 Nov 17. Epub 2018 Nov 17.

Department of Hematology and Medical Oncology, Emory University, Atlanta, GA, USA.

Background: Pancreatic ductal adenocarcinoma (PDAC) continues to be one of the most aggressive and lethal diseases in the world. The success of immunotherapy in other types of malignancy has led to further trials to understand better the role of immunotherapy in PDAC. However, initial studies with immunotherapy, namely, the checkpoint inhibitors, in PDAC have not been met with the same outcomes. Read More

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http://link.springer.com/10.1007/s12029-018-0179-z
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http://dx.doi.org/10.1007/s12029-018-0179-zDOI Listing
November 2018
8 Reads

Follicular Dendritic Cell Sarcoma of Gastrointestinal Tract: an Uncommon Lesion, Commonly Missed.

J Gastrointest Cancer 2018 Nov 15. Epub 2018 Nov 15.

Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan.

Introduction: Follicular dendritic cell sarcoma (FDCS) is a rare neoplasm, accounting for only 0.4% of soft-tissue sarcomas. It shows both nodal and extranodal involvement. Read More

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http://link.springer.com/10.1007/s12029-018-0178-0
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http://dx.doi.org/10.1007/s12029-018-0178-0DOI Listing
November 2018
2 Reads

Outcomes of Neoadjuvant Chemoradiation in Patients with Gastro-esophageal Junction Adenocarcinoma: a Retrospective Cohort Study in Iran.

J Gastrointest Cancer 2018 Nov 7. Epub 2018 Nov 7.

Department of Radiation Oncology, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran.

Purpose: The optimal treatment for locally advanced GEJ and cardia adenocarcinoma is controversial. Several studies have shown that treating these patients with neoadjuvant chemoradiotherapy followed by surgery leads to survival benefits, and there are also studies that have declared conflicting results. It seems that there is still room for discussion. Read More

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http://link.springer.com/10.1007/s12029-018-0155-7
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http://dx.doi.org/10.1007/s12029-018-0155-7DOI Listing
November 2018
6 Reads

Synchronous Adeno-squamous Carcinoma of Gallbladder and Adenocarcinoma of Common Bile Duct: Twin Trouble.

J Gastrointest Cancer 2018 Nov 6. Epub 2018 Nov 6.

Department of Diagnostic and Interventional Radiology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.

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http://dx.doi.org/10.1007/s12029-018-0177-1DOI Listing
November 2018
1 Read

Radio-pathological Correlation of 18F-FDG PET in Characterizing Gallbladder Wall Thickening.

J Gastrointest Cancer 2018 Nov 6. Epub 2018 Nov 6.

Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.

Aim: Thick-walled gallbladder is difficult to characterize on conventional imaging. 18F-FDG PET was used to differentiate benign and malignant wall thickness and compared with histopathology.

Methods: Thirty patients with gallbladder (GB) wall thickening (focal > 4 mm and diffuse > 7 mm), underwents uspected on  ultrasound, or CT scan, and underwent 18F-FDG PET. Read More

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http://link.springer.com/10.1007/s12029-018-0176-2
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http://dx.doi.org/10.1007/s12029-018-0176-2DOI Listing
November 2018
5 Reads

Recurrent Pancreatitis Secondary to Diffuse Large B Cell Lymphoma.

J Gastrointest Cancer 2018 Nov 5. Epub 2018 Nov 5.

Section of Digestive Diseases and Nutrition, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.

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http://dx.doi.org/10.1007/s12029-018-0175-3DOI Listing
November 2018

Acknowledgment of Reviewers 2016 and 2017.

Authors:

J Gastrointest Cancer 2018 Nov 5. Epub 2018 Nov 5.

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http://dx.doi.org/10.1007/s12029-018-0174-4DOI Listing
November 2018

Testicular Choriocarcinoma Metastasizing to the Small Bowel Causing Intussusception: Case Report.

J Gastrointest Cancer 2018 Oct 27. Epub 2018 Oct 27.

Pathology Department, Texas Tech Health and Science Center, El Paso, TX, USA.

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http://dx.doi.org/10.1007/s12029-018-0172-6DOI Listing
October 2018
1 Read

Platelet and Neutrophil Counts as Predictive Markers of Neoadjuvant Therapy Efficacy in Rectal Cancer.

J Gastrointest Cancer 2018 Oct 24. Epub 2018 Oct 24.

Division of Clinical Sciences, Northern Ontario School of Medicine, Sudbury, ON, Canada.

Aims: To investigate pretreatment platelet and neutrophil counts as well as a combined platelet-neutrophil (PN) index for prognostic information in patients with rectal adenocarcinoma that received neoadjuvant treatment.

Patients And Methods: Charts from 164 patients with localized rectal adenocarcinoma were retrospectively reviewed, and 112 patients with complete data were included in the study. Patients were stratified in groups according to their neutrophil counts, platelet counts, and a combined platelet/neutrophil (PN) index. Read More

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http://link.springer.com/10.1007/s12029-018-0173-5
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http://dx.doi.org/10.1007/s12029-018-0173-5DOI Listing
October 2018
3 Reads

Improved Survival of Hepatocellular Carcinoma Patients Diagnosed with a Dedicated Screening Programme-a Propensity Score Adjusted Analysis.

J Gastrointest Cancer 2018 Oct 22. Epub 2018 Oct 22.

Hepatology and Liver Transplant Medicine Unit, Flinders Medical Centre, Bedford Park, SA, Australia.

Aim: To assess the overall survival (OS) in those with hepatocellular carcinoma (HCC) diagnosed within a programmatic, centrally co-ordinated, regional screening programme.

Methods: A retrospective cohort analysis of consecutive HCC patients diagnosed between 2004 and 2013. Patients were followed up till death or end of study period (30 April 2015). Read More

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http://dx.doi.org/10.1007/s12029-018-0171-7DOI Listing
October 2018
1 Read

Stereotactic Body Radiation Therapy (SBRT) Using CyberKnife in Oligometastatic Cancer Patients; Retrospective Evaluation, Single Institution Experience.

J Gastrointest Cancer 2018 Oct 6. Epub 2018 Oct 6.

Radiation oncology department King Faisal specialized hospital and research center, Riyadh, Saudi Arabia.

Objectives: We retrospectively evaluate local control rate at 6 months and 1 year in oligometastatic cancer patients treated with SBRT using CyberKnife.

Methods: Total of 21 patients with 24 treatment sites from February 2014 till June 2017 who were treated with SBRT in our institution were included in this study.

Results: Eleven patients were males, 10 patients were females, median age at diagnosis was 63 years, and colorectal cancer is the most commonly diagnosed cancer in 18 patients. Read More

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http://link.springer.com/10.1007/s12029-018-0170-8
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http://dx.doi.org/10.1007/s12029-018-0170-8DOI Listing
October 2018
6 Reads

Faecal Occult Blood Point-of-Care Tests.

J Gastrointest Cancer 2018 Dec;49(4):402-405

Department of Clinical Biochemistry, Institute of Pediatrics, Jagiellonian University Medical College, Wielicka St 265, 30-663, Cracow, Poland.

Background: Early detection of colorectal cancer decreases the risk of mortality. Faecal occult blood tests (FOBT) are recognised as a useful tool for colorectal cancer screening. These non-invasive, rapid, and easy-to-carry assays are very often used as a point-of-care test and for self-testing. Read More

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http://link.springer.com/10.1007/s12029-018-0169-1
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http://dx.doi.org/10.1007/s12029-018-0169-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208834PMC
December 2018
3 Reads

Clostridium septicum Myonecrosis Secondary to an Occult Small Bowel Adenocarcinoma.

J Gastrointest Cancer 2018 Sep 10. Epub 2018 Sep 10.

Spectrum Health Hospital, Acute Care Surgery, 221 Michigan NE, Suite 402, Grand Rapids, MI, 49503, USA.

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http://dx.doi.org/10.1007/s12029-018-0168-2DOI Listing
September 2018

Polymorphisms of Genes Related to Function and Metabolism of Vitamin D in Esophageal Adenocarcinoma.

J Gastrointest Cancer 2018 Sep 5. Epub 2018 Sep 5.

Norton Thoracic Institute, St. Joseph's Hospital and Medical Center, 500 W. Thomas Road, Suite 500, Phoenix, AZ, USA.

Purpose: The vitamin D receptor (VDR) endocrine system has emerged as an endogenous pleiotropic biological cell regulator with anti-neoplastic effects on breast, colorectal, and prostatic adenocarcinomas. We studied the association of gene expression, polymorphisms of VDR, CYP27B1, and CYP24A1 genes and serum vitamin D levels as surrogate markers of disease progression in patients with acid reflux, Barrett's esophagus (BE), or esophageal adenocarcinoma (EAC).

Methods: We analyzed blood and tissue samples from patients with biopsy-confirmed BE or EAC for vitamin D levels, gene expressions, and polymorphisms in VDR (FokI [F/f], BsmI [B/b], ApaI [A/a], and TaqI [T/t]), CYP27B1 (HinfI [H/h]), and CYP24A1 (Hpy1881 [Y/y]). Read More

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http://dx.doi.org/10.1007/s12029-018-0164-6DOI Listing
September 2018
7 Reads

Gallbladder Carcinosarcoma with Mirizzi Syndrome: a Rare Presentation.

J Gastrointest Cancer 2018 Sep 4. Epub 2018 Sep 4.

Department of Surgical Gastroenterology, All India Institute of Medical Sciences, Basni Industrial Area, Phase-II, Jodhpur, Rajasthan, 342005, India.

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http://dx.doi.org/10.1007/s12029-018-0167-3DOI Listing
September 2018
1 Read

Second-Line Treatment for Advanced Pancreatic Adenocarcinoma: Is There a Role for Gemcitabine?

J Gastrointest Cancer 2018 Sep 3. Epub 2018 Sep 3.

Department of Oncology, Hospital Sírio-Libanes, SGAS 613-conjunto E lote 95-Asa Sul, Brasília, DF, 70200-001, Brazil.

Purpose: Advanced pancreatic adenocarcinoma (PA) is an aggressive disease that has poor prognosis and frequently interferes with patient's quality of life. There has been progress in first-line regimens; however, there is no standard second-line regimen. The aim of this study is to analyze second-line gemcitabine after first-line fluorouracil (FU) + leucovorin (LV) + irinotecan + oxaliplatin (FOLFIRINOX) regimen. Read More

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http://link.springer.com/10.1007/s12029-018-0166-4
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http://dx.doi.org/10.1007/s12029-018-0166-4DOI Listing
September 2018
5 Reads

Transcript Level of MicroRNA Processing Elements in Gastric Cancer.

J Gastrointest Cancer 2018 Aug 31. Epub 2018 Aug 31.

Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Background: Aberrant expression of microRNAs (miRNAs) has been implicated in the etiopathogenesis and development of various cancers. Drosha and Dicer are the main components of the miRNA biosynthesis machine. Another enzyme, DGCR8, is the assistant of Drosha in the processing complex. Read More

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http://link.springer.com/10.1007/s12029-018-0154-8
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http://dx.doi.org/10.1007/s12029-018-0154-8DOI Listing
August 2018
13 Reads

Significance of HER2 and Ki-67 in Preneoplastic Lesions and Carcinoma of Gallbladder.

J Gastrointest Cancer 2018 Aug 29. Epub 2018 Aug 29.

Department of Pathology, ESI PGIMSR, Manicktala Kolkata, 54 Bagmari Road, Kolkata, West Bengal, 7000054, India.

Background: HER2 is an oncoprotein which is overexpressed in several cancers including breast and stomach. Several studies have shown that HER2 is overexpressed in gallbladder cancer and in precancerous lesions. The present study was undertaken to assess pattern and level of expression of HER2 in metaplasia, dysplasia, and different stages of gallbladder carcinoma, which would determine its suitability as a prognostic biomarker in neoplastic transformation of gallbladder epithelium. Read More

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http://dx.doi.org/10.1007/s12029-018-0162-8DOI Listing
August 2018
5 Reads

A Modified Low-Cost Technique of Cytoreductive Surgery (CRS) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Two Patients: a Solution for Pseudomyxoma Peritonei in the Indian Scenario?

J Gastrointest Cancer 2018 Aug 24. Epub 2018 Aug 24.

Department of Surgery, Renal Transplant Unit, Postgraduate Institute of Medical Education and Research (PGIMER) and Dr. Ram Manohar Lohia Hospital (RMLH), Baba Kharak Singh Marg, Delhi, 110001, India.

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http://dx.doi.org/10.1007/s12029-018-0161-9DOI Listing
August 2018
2 Reads

The Prognostic Value of Cancer Stem Cell Markers (Notch1, ALDH1, and CD44) in Primary Colorectal Carcinoma.

J Gastrointest Cancer 2018 Aug 23. Epub 2018 Aug 23.

Department of General Surgery, Faculty of Medicine, Zagazig University, Markaz El-Zakazik, Ash Sharqia Governorate, 44519, Egypt.

Background: Cancer stem cells proved to have a vital role in cell migration, invasion, metastasis, and treatment resistance of colorectal cancer (CRC) that subsequently lead to poor clinical outcomes. These stem cells may be a novel therapeutic target for the management of CRC progression. Signals of the Notch-1 pathway are responsible for acquisition of stem cell characters. Read More

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http://dx.doi.org/10.1007/s12029-018-0156-6DOI Listing

A Comparative Study of Spatial Distribution of Gastrointestinal Cancers in Poverty and Affluent Strata (Kermanshah Metropolis, Iran).

J Gastrointest Cancer 2018 Aug 23. Epub 2018 Aug 23.

Social Development and Health Promotion Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Introduction: The trend of cancers has witnessed a twofold rise in the last three decades, which is expected to be fivefold by 2030. On the other hand, gastrointestinal cancers have turned into one of the health issues in many societies. Given the presence of gastrointestinal cancer hot spots and evidence of health inequalities across Kermanshah Metropolis and the results of studies signaling the association between gastrointestinal cancers and socioeconomic status of individuals as well as evidence of unequal socioeconomic opportunities in this metropolis, the present study aimed to investigate the spatial distribution of gastrointestinal cancers in the poverty and affluent strata of Kermanshah Metropolis, Iran. Read More

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http://dx.doi.org/10.1007/s12029-018-0163-7DOI Listing

Treatment Outcomes in Patients with Metastatic Neuroendocrine Tumors: a Retrospective Analysis of a Community Oncology Database.

J Gastrointest Cancer 2018 Aug 18. Epub 2018 Aug 18.

The West Clinic, 100 N Humphreys Boulevard, Memphis, TN, 38120, USA.

Purpose: Metastatic neuroendocrine tumors (mNETs) are rare, heterogeneous tumors that present diagnostic and treatment challenges, with limited data on the management of mNETs in clinical practice. The present study was designed to identify current diagnostic and treatment patterns in mNET patients treated in the US community oncology setting.

Methods: Patient-level data was collected from medical records of adults with mNETs from the Vector Oncology Data Warehouse, a comprehensive US community oncology network database. Read More

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http://dx.doi.org/10.1007/s12029-018-0160-xDOI Listing
August 2018
4 Reads

Tumor Platinum Concentrations and Pathological Responses Following Cisplatin-Containing Chemotherapy in Gastric Cancer Patients.

J Gastrointest Cancer 2018 Aug 16. Epub 2018 Aug 16.

Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Room 5-719, 610 University Avenue, Toronto, ON, M5G 2M9, Canada.

Purpose: There is a wide range in tumor response following preoperative chemotherapy in locally advanced gastric or gastroesophageal junction cancers. We investigated the relationship between tumor platinum levels and pathological responses in these patients.

Methods: Tumor and adjacent normal tissues were retrieved. Read More

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http://dx.doi.org/10.1007/s12029-018-0153-9DOI Listing

Outcomes Following Resection of Hepatocellular Carcinoma in the Absence of Cirrhosis.

J Gastrointest Cancer 2018 Aug 16. Epub 2018 Aug 16.

Department of Surgery, Division of Surgical Oncology, University of Tennessee Health Science Center, 910 Madison Avenue, 3rd Floor, Memphis, TN, 38163, USA.

Background: Hepatocellular carcinoma (HCC) occasionally occurs in non-cirrhotic patients; however, outcomes for these patients are not extensively documented.

Methods: We performed an institutional review of patients without cirrhosis who underwent resection for HCC. Clinical data were evaluated to identify factors impacting recurrence-free survival (RFS) and overall survival (OS). Read More

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http://dx.doi.org/10.1007/s12029-018-0152-xDOI Listing

Impact of Prior Malignancy on Survival Outcomes of Stage IV Pancreatic Adenocarcinoma: SEER-Based Cohort.

J Gastrointest Cancer 2018 Aug 14. Epub 2018 Aug 14.

Clinical Oncology Department, Faculty of Medicine, Ain Shams University, Lofty Elsayed Street, Cairo, 11566, Egypt.

Purpose: Pancreatic cancer is one of the most fatal malignancies and the fourth leading cause of cancer-related mortality in the USA. Most clinical trials involving pancreatic adenocarcinoma (PAC) patients exclude subjects with a prior malignancy because of the possible effect of prior malignancies on survival. However, no data in the medical literature support this assumption. Read More

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http://dx.doi.org/10.1007/s12029-018-0158-4DOI Listing

Hepatocellular Carcinoma with Orbital Metastasis: a Unique Multidisciplinary Case Report.

J Gastrointest Cancer 2018 Aug 13. Epub 2018 Aug 13.

Division of Hematology/Oncology, St. Louis University School of Medicine, Second Floor, Cancer Center Building, 3655 Vista Avenue, St. Louis, MO, 63110, USA.

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http://dx.doi.org/10.1007/s12029-018-0159-3DOI Listing

Emergency Laparoscopic Gastrectomy for Intraperitoneal Ruptured Gastric Gastrointestinal Stromal Tumor.

J Gastrointest Cancer 2018 Aug 9. Epub 2018 Aug 9.

Department of Gastrointestinal Surgery, Inonu University, 44315, Malatya, Turkey.

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http://dx.doi.org/10.1007/s12029-018-0157-5DOI Listing

Von Meyenburg Complexes Mimicking Diffuse Metastatic Liver Disease.

J Gastrointest Cancer 2018 Aug 6. Epub 2018 Aug 6.

2nd Department of Surgery, Army General Hospital, 19 Taxiarhon Street, 19014 Kapandriti, Athens, Greece.

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http://dx.doi.org/10.1007/s12029-018-0151-yDOI Listing
August 2018
1 Read

Treatment Patterns Among Patients with Metastatic and/or Unresectable Gastric Cancer in Brazil.

J Gastrointest Cancer 2018 Aug 4. Epub 2018 Aug 4.

Lilly Research Centre, Eli Lilly and Company, Erl Wood Manor, Sunninghill Road, Windlesham, Surrey, GU20 6PH, UK.

Purpose: In Brazil, patients with gastric cancer have not been systematically followed-up and evaluated, thus data regarding patterns of care and outcomes are scarce or missing. The objective of this study was to evaluate patterns of care of advanced gastric cancer in standard practice in Brazil.

Methods: This was an observational, multicenter, retrospective study, which included patients with metastatic and/or unresectable gastric cancer (MGC) who underwent at least one line of treatment. Read More

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http://dx.doi.org/10.1007/s12029-018-0145-9DOI Listing
August 2018
10 Reads

Association of ki67 Index with Recurrence in Gastrointestinal Stromal Tumors.

J Gastrointest Cancer 2018 Dec;49(4):543-547

Surgical Oncology, Instituto Nacional de Cancerología, Mexico City, Mexico.

Purpose: Gastrointestinal stromal tumors (GIST) have the potential to recur and metastasize. Several prognostic schemes have been developed but none are precise enough and most times the pathologist faces a small biopsy where it is not possible to evaluate the mitotic count. Our aim was to determine the influence of ki67 index and other clinicopathologic characteristics in the recurrence of GIST. Read More

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http://dx.doi.org/10.1007/s12029-018-0150-zDOI Listing
December 2018
1 Read

Vitamin D Levels in Patients with Colorectal Cancer Before and After Treatment Initiation.

J Gastrointest Cancer 2018 Jul 30. Epub 2018 Jul 30.

UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA.

Purpose: We aimed to described 25-hydroxyvitamin D [25(OH)D] levels in newly diagnosed colorectal cancer (CRC) patients and to re-evaluate levels after chemotherapy.

Methods: Permanent residents of the San Francisco Bay Area with a new CRC diagnosis of any stage were recruited prior to any non-surgical therapy. Serum 25(OH)D levels were measured at time of diagnosis and 6-month follow-up. Read More

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http://dx.doi.org/10.1007/s12029-018-0147-7DOI Listing
July 2018
8 Reads

Pre-treatment Peripheral Neutrophil-Lymphocyte Ratio as a Prognostic Marker in Gastric Cancer.

J Gastrointest Cancer 2018 Jul 30. Epub 2018 Jul 30.

Clinical Oncology Department, Faculty of Medicine, Ain Shams University, Abbasia, Cairo, Egypt.

Background: Gastric cancer is the fifth cancer worldwide. Inflammatory response increases metastasis through apoptosis inhibition and angiogenesis augmentation. The neutrophil-lymphocyte ratio (NLR), which is a balance between pro-cancer inflammatory and anti-cancer immune responses, was proved as prognostic marker. Read More

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http://dx.doi.org/10.1007/s12029-018-0144-xDOI Listing

Acute Portal Vein Thrombosis Predicts Concomitant Diagnosis of Hepatocellular Carcinoma in Cirrhotic Patients.

J Gastrointest Cancer 2018 Jul 25. Epub 2018 Jul 25.

Institute of Gastroenterology and Liver Diseases, Department of Internal Medicine, Hebrew University-Hadassah Medical Center, P.O.B. 12000, IL-91120, Jerusalem, Israel.

Purpose: Portal vein thrombosis (PVT) is a common condition in cirrhotic patients and mostly attributed to portal hypertension. The objective of our study was to examine the association of PVT with hepatocellular carcinoma (HCC) in cirrhotic patients.

Methods: A retrospective study was performed to identify cirrhotic patients with thrombosis of the portal system. Read More

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http://dx.doi.org/10.1007/s12029-018-0149-5DOI Listing
July 2018
1 Read

Neoadjuvant Radiotherapy Versus No Radiotherapy for Stage IV Rectal Cancer: a Systematic Review and Meta-analysis.

J Gastrointest Cancer 2018 Dec;49(4):389-401

Department of Radiation Oncology, Benavides Cancer Institute, University of Santo Tomas Hospital, España Boulevard, 1008, Manila, Philippines.

Purpose: The aim of this study is to review the contemporary evidence comparing neoadjuvant radiotherapy (NRT) versus no radiotherapy (no RT) in patients with stage IV rectal cancer.

Methods: Literature was searched for studies using the following databases: Pubmed, EMBASE, Science Direct, Scopus, ASCOpubs, the Cochrane Library, and Google Scholar. Studies reporting outcomes for stage IV rectal cancer patients who underwent NRT or no RT were selected. Read More

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http://dx.doi.org/10.1007/s12029-018-0141-0DOI Listing
December 2018

"Pure" High-Grade Large Cell Neuroendocrine Carcinoma Arising from Low- and High-Grade Dysplasia of the Gallbladder: Case Report and Review of the Literature.

J Gastrointest Cancer 2018 Jul 25. Epub 2018 Jul 25.

Department of Pathology, Tulane University School of Medicine, 1430 Tulane Avenue, SL-79, New Orleans, LA, 70112, USA.

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http://dx.doi.org/10.1007/s12029-018-0148-6DOI Listing
July 2018
1 Read

Outcomes After Surgical Resection Differ by Primary Tumor Location for Metastatic Gastrointestinal Stromal Tumors (GISTs): a Propensity Score Matching Population Study.

J Gastrointest Cancer 2018 Jul 23. Epub 2018 Jul 23.

Second Department of Surgery, University General Hospital of Alexandroupoli, Democritus University of Thrace Medical School, 68100, Alexandroupoli, Greece.

Purpose: Primary tumor location has been identified as an important prognostic factor among patients with gastrointestinal stromal tumors (GISTs). The purpose of this study is to identify how primary tumor location may affect outcomes after resection for patients with metastatic GISTs.

Methods: Patients with GISTs and distant metastases at diagnosis were identified in the Surveillance Epidemiology and End Results (SEER) database. Read More

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http://dx.doi.org/10.1007/s12029-018-0137-9DOI Listing
July 2018
2 Reads

Extramedullary Plasmacytoma of the Pancreas Complicated with Left-Sided Portal Hypertension-a Case Report and Literature Review.

J Gastrointest Cancer 2018 Jul 23. Epub 2018 Jul 23.

Department of Internal Medicine, 1st Medical Faculty Charles University and Central Military Hospital Prague, U Vojenské nemocnice 1200, 169 02, Prague, Czech Republic.

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http://dx.doi.org/10.1007/s12029-018-0146-8DOI Listing
July 2018
4 Reads

The Potential Role of TNF-α (rs361525 and rs1800629) in Hepatocellular Carcinoma: Multivariate Analysis (Meta-Analysis).

J Gastrointest Cancer 2018 Jul 20. Epub 2018 Jul 20.

Faculty of Biological Science and Biotechnology, Shahid Beheshti University, Tehran, Iran.

Purpose: Tumor necrosis factor-α has been suggested to play a crucial role in the development andprogression of hepatocellular carcinoma (HCC). Previous reports have indicated that rs361525 and rs1800629 might be risk factors for various cancers. Increasing studies have been conducted on the association of these two SNPs with HCC risk but the results remain inconclusive. Read More

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http://dx.doi.org/10.1007/s12029-018-0135-yDOI Listing

Epidemiology of Colorectal Cancer and the Risk Factors in Kermanshah Province-Iran 2009-2014.

J Gastrointest Cancer 2018 Jul 19. Epub 2018 Jul 19.

Nursing and Midwifery School, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Introduction And Objective: Colorectal cancer is the fourth prevalent cancer in the world and there are several factors effective on development of the disease. These factors vary based on geographical distribution. The present study is aimed at surveying epidemiology of colorectal cancer and its risk factors in Kermanshah-Iran between 2009 and 2014. Read More

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http://dx.doi.org/10.1007/s12029-018-0142-zDOI Listing
July 2018
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Duodenal Invasion of Pancreatic Cancer Resulting in Hematemesis.

J Gastrointest Cancer 2018 Jul 16. Epub 2018 Jul 16.

Department of Gastroenterology, Hepatology and Nutrition, Allegheny General Hospital, 320 E North Ave, Pittsburgh, PA, 15212, USA.

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http://dx.doi.org/10.1007/s12029-018-0143-yDOI Listing

Dose Escalation with Simultaneous Integrated Boost (SIB) Using Volumetric Modulated Arc Therapy (VMAT) in Rectal Cancer.

J Gastrointest Cancer 2018 Jul 14. Epub 2018 Jul 14.

Section of Colon and Rectal Surgery, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia.

Purpose: Assess feasibility-rate of PCR, short-term toxicity after neoadjuvant concurrent chemoradiation (NACRT) delivered via simultaneous integrated boost (SIB) using volumetric modulated arc therapy (VMAT) technique for locally advanced rectal cancer.

Methods: Retrospective evaluation of patients with locally advanced rectal cancer treated with VMAT-SIB technique preoperatively at an academic tertiary care center in Riyadh, Saudi Arabia between February 2013 and March 2017.

Results: One hundred patients with depth of invasion staged as T3/T4 or T2 in 93 and seven patients, respectively. Read More

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http://dx.doi.org/10.1007/s12029-018-0133-0DOI Listing
July 2018
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The Neutrophil-Lymphocyte Ratio Is an Independent Prognostic Factor for Overall Survival in Hispanic Patients with Gastric Adenocarcinoma.

J Gastrointest Cancer 2018 Jul 13. Epub 2018 Jul 13.

Departamento de Bioquímica, Escuela de Medicina and Centro de Investigación en Estructuras Microscópicas (CIEMIC), Universidad de Costa Rica, San Pedro, Costa Rica.

Introduction: High values of neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) are related with poor prognosis in patients with gastric cancer. However, this association has been rarely assessed in Hispanic populations that show important clinicopathological differences to Asian and Caucasian patients. In this study, we determined the prognostic value of these biomarkers in Hispanic patients from Costa Rica. Read More

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http://dx.doi.org/10.1007/s12029-018-0134-zDOI Listing

Laparoscopic Liver Resection in a Case of Asymptomatic Elderly Patient with Caroli Syndrome.

J Gastrointest Cancer 2018 Jul 13. Epub 2018 Jul 13.

Department of General and Visceral Surgery, Sozialstiftung Bamberg, Bamberg, Germany.

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http://dx.doi.org/10.1007/s12029-018-0139-7DOI Listing

Alpha-fetoprotein Secreting Neuroendocrine Carcinoma of the Liver: a Case Report and Literature Review.

J Gastrointest Cancer 2018 Jul 13. Epub 2018 Jul 13.

Department of Radiology, Trakya University Faculty of Medicine, Edirne, Turkey.

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http://dx.doi.org/10.1007/s12029-018-0140-1DOI Listing
July 2018
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