9,066 results match your criteria Journal of Gastroenterology and Hepatology[Journal]


The zinc finger protein GATA4 induces MET and cellular senescence through the NF-κB pathway in hepatocellular carcinoma.

J Gastroenterol Hepatol 2019 Apr 17. Epub 2019 Apr 17.

Laboratory Animal Center, Chongqing Medical University, Chongqing.

Background And Aim: The high mortality and poor prognosis of hepatocellular carcinoma (HCC) have raised the public attention. Gene therapy is considered as a promising treatment option for cancer; thus, finding a new therapeutic target for hepatocellular carcinoma is urgently needed. GATA4 is a tumor suppressor gene in multiple cancers, but its role in HCC is unclear. Read More

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http://dx.doi.org/10.1111/jgh.14684DOI Listing
April 2019
1 Read

Gastrointestinal: An esophageal subepithelial lesion.

J Gastroenterol Hepatol 2019 Apr 10. Epub 2019 Apr 10.

Department of Gastroenterology and Hepatology, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jgh.14661
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http://dx.doi.org/10.1111/jgh.14661DOI Listing
April 2019
1 Read

The suppressive role of HYAL1 and HYAL2 in the metastasis of colorectal cancer.

J Gastroenterol Hepatol 2019 Mar 14. Epub 2019 Mar 14.

Department of Molecular Biology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.

Background: Hyaluronidases (HAases), enzymes that degrade hyaluronan, have been widely investigated in cancer biology. However, whether HAases serve as tumor promoters or suppressors has been controversial in different cancers, and the exact role of HAases in colorectal cancer (CRC) has not been elucidated.

Methods: The expression levels of HYAL1, HYAL2, and HYAL3 in cancer and corresponding normal tissues from CRC patients were examined via immunohistochemistry. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jgh.14660
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http://dx.doi.org/10.1111/jgh.14660DOI Listing
March 2019
1 Read

Improvement of hyponatremia in cirrhosis is associated with improved complex information processing.

J Gastroenterol Hepatol 2019 Apr 9. Epub 2019 Apr 9.

Liver Unit, Hospital Clinic of Barcelona, University of Barcelona, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), and Centro de Investigaciones en Red Hepatologia y Digestivas (CIBEReHD), Barcelona, Spain.

Background And Aim: Hyponatremia, a cause of brain dysfunction and risk factor for hepatic encephalopathy, is frequent in patients with advanced cirrhosis and ascites. The interdependence of liver failure and hyponatremia makes it difficult to separate the effects of each on cognitive function. The objective was to assess whether an increase in plasma sodium in patients with cirrhosis and ascites leads to an improvement in cognitive function. Read More

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http://dx.doi.org/10.1111/jgh.14683DOI Listing
April 2019
1 Read

A History of Malignancy and Relevant Symptoms May Predict a Positive CT Enterography in Obscure GI Bleeds.

J Gastroenterol Hepatol 2019 Apr 9. Epub 2019 Apr 9.

Department of Medicine, University Health Network, University of Toronto, Toronto, ON, Canada.

Background And Aim: This study aimed to assess the clinical utility of computed tomography enterography (CTE) and identify factors associated with a diagnostic CTE for patients with obscure gastrointestinal bleeding (OGIB).

Methods: A retrospective observational study was performed at a Canadian tertiary care centre from 2005-2015. A total of 138 patients underwent a CTE for OGIB. Read More

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http://dx.doi.org/10.1111/jgh.14682DOI Listing

The value of DNA image cytometry combined with brush routine cytology in diagnosing indeterminate biliary strictures: A large sample size retrospective study.

J Gastroenterol Hepatol 2019 Apr 8. Epub 2019 Apr 8.

Department of Gastroenterology, Changhai Hospital, Second Military Medical University/Naval Medical University, Shanghai, China.

Background And Objective: Brush cytology is widely applied to diagnosis indeterminate biliary stricture but suffer from low sensitivity. Changes in DNA content is a character of malignant cell and can be detected by DNA image cytometry (DNA-ICM). The study aimed to estimate the value of routine cytology (RC), DNA-ICM, and their combination in diagnosing indeterminate biliary strictures. Read More

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http://dx.doi.org/10.1111/jgh.14681DOI Listing

Gastrointestinal: A rare tumor of inferior vena cava diagnosed by endoscopic ultrasound-guided fine needle aspiration.

J Gastroenterol Hepatol 2019 Apr 7. Epub 2019 Apr 7.

Department of Cytology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

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http://dx.doi.org/10.1111/jgh.14663DOI Listing

Controversies and reality of the FODMAP diet for patients with irritable bowel syndrome.

J Gastroenterol Hepatol 2019 Mar 8. Epub 2019 Mar 8.

Department of Gastroenterology, The Alfred Hospital, Monash University, Melbourne, Victoria, Australia.

Since its first trial showing evidence of efficacy for managing symptoms of irritable bowel syndrome, the fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) diet has been gaining popularity but not without criticism. Application of the diet has changed from a rigid list of "allowed" and "not allowed" foods to a structured program of initial FODMAP restriction followed by food reintroduction and finally personalization so that patients are empowered to adjust their diet themselves to achieve good predictability of symptoms. Safety concerns of the diet have centered around its initial elimination leading to compromise of nutritional and psychological health, but careful patient assessment and management, preferably through a FODMAP-trained dietitian, will reduce the risk of such negative health outcomes. Read More

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http://dx.doi.org/10.1111/jgh.14650DOI Listing
March 2019
4 Reads

Gastrointestinal: A case of spontaneous rupture of esophageal diverticulum.

Authors:
X Ding T Huang X Zou

J Gastroenterol Hepatol 2019 Apr 3. Epub 2019 Apr 3.

Department of Gastroenterology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China.

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http://dx.doi.org/10.1111/jgh.14662DOI Listing

Upper gastrointestinal bleeding in Egyptian patients with cirrhosis: Post-therapeutic outcome and prognostic indicators.

J Gastroenterol Hepatol 2019 Mar 14. Epub 2019 Mar 14.

Hepatology Department, National Liver Institute, University of Menoufia, Shebeen El-Kom, Egypt.

Background And Aim: Upper gastrointestinal bleeding (UGIB) is a serious complication of portal hypertension in cirrhotic patients. The objective of this study is to identify the risk factors for morbidity and mortality occurring after an UGIB attack.

Methods: A total of 1097 UGIB attacks in 690 patients with liver cirrhosis were studied. Read More

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http://dx.doi.org/10.1111/jgh.14659DOI Listing
March 2019
1 Read

A new sub-stage classification strategy for Barcelona Clinic Liver Cancer stage B patients with hepatocellular carcinoma.

J Gastroenterol Hepatol 2019 Apr 1. Epub 2019 Apr 1.

Liver Cancer Institute & Zhongshan Hospital, Fudan University, Shanghai, China.

Background And Aim: Patients with Barcelona Clinic Liver Cancer stage B hepatocellular carcinoma are heterogeneous population, and the classifications available could not predict the prognosis accurately. Herein, we proposed a new sub-stage classification method, Scoring Method for Intermediate Stage, for precise classification and clinical guidance in hepatocellular carcinoma patients within Barcelona Clinic Liver Cancer stage B.

Methods: 1026 stage B patients of hepatocellular carcinoma who underwent transcatheter arterial chemoembolization as first line treatment in liver cancer institute, Zhongshan hospital, Fudan University were retrospectively enrolled. Read More

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http://dx.doi.org/10.1111/jgh.14673DOI Listing
April 2019
1 Read

Epidemiology, characteristics and survival of post-colonoscopy colorectal cancer in Asia: a population-based study.

J Gastroenterol Hepatol 2019 Apr 1. Epub 2019 Apr 1.

Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong.

Background And Aims: Population-based studies on post-colonoscopy colorectal cancer (CRC) from Asia are sparse. We aimed to determine the characteristics and predictive factors and survival of post-colonoscopy CRC in Hong Kong.

Methods: This is a territory-wide retrospective cohort study. Read More

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http://dx.doi.org/10.1111/jgh.14674DOI Listing
April 2019
2 Reads

The usefulness of intestinal real-time virtual sonography in patients with inflammatory bowel disease.

J Gastroenterol Hepatol 2019 Apr 1. Epub 2019 Apr 1.

Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Japan.

Background And Aim: Trans-abdominal ultrasonography (US) examination for the intestine is often difficult and its precedence for intestinal examination depends on accessibility to experienced ultrasonographers. Real-time virtual sonography (RVS) assists examination of US as a fusion method by synchronizing US images with pre-captured computed tomography (CT) or magnetic resonance (MR) images. We aimed to evaluate the feasibility to use RVS for the examination of the intestine. Read More

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http://dx.doi.org/10.1111/jgh.14670DOI Listing
April 2019
3 Reads

Paritaprevir/ritonavir, ombitasvir plus dasabuvir for East-Asian non-cirrhotic hepatitis C virus genotype 1b patients receiving hemodialysis.

J Gastroenterol Hepatol 2019 Apr 1. Epub 2019 Apr 1.

Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

Background And Aim: Data regarding the efficacy and safety of paritaprevir/ritonavir, ombitasvir plus dasabuvir (PrOD) for East-Asian non-cirrhotic hepatitis C virus genotype 1b (HCV GT1b) patients receiving hemodialysis were limited.

Methods: Forty-six HCV GT1b non-cirrhotic patients receiving hemodialysis who received PrOD for 12 weeks were prospectively enrolled 7 academic centers in Taiwan. The primary efficacy endpoint was sustained virologic response 12 weeks off-therapy (SVR ). Read More

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http://dx.doi.org/10.1111/jgh.14672DOI Listing
April 2019
1 Read

When repeated Helicobacter pylori therapies fail, what should we do?

J Gastroenterol Hepatol 2019 Apr;34(4):627-628

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http://dx.doi.org/10.1111/jgh.14668DOI Listing

Cytoprotective agent for peptic ulcer prevention in patients taking dual antiplatelet agents: A randomized, double-blind placebo-controlled trial.

J Gastroenterol Hepatol 2019 Mar 28. Epub 2019 Mar 28.

Division of Gastroenterology, Chulalongkorn University and King Chulalongkorn Memorial Hospital The Thai Red Cross, Bangkok, Thailand.

Background: Long-term use of dual antiplatelets is increasing, and most patients need primary peptic ulcer prophylaxis. The long-term use of proton pump inhibitors (PPIs) is associated with adverse events. We evaluated the efficacy of rebamipide for peptic ulcer prevention. Read More

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http://dx.doi.org/10.1111/jgh.14671DOI Listing
March 2019
1 Read

Gastrointestinal: Multi-modality imaging of extraskeletal Ewing sarcoma of the stomach.

Authors:
A C Hopp B D Nguyen

J Gastroenterol Hepatol 2019 Mar 25. Epub 2019 Mar 25.

Department of Radiology, Mayo Clinic Arizona, Scottsdale, Arizona, USA.

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http://dx.doi.org/10.1111/jgh.14638DOI Listing

Risk factors of early rebleeding in the endoscopic management of colonic diverticular bleeding.

J Gastroenterol Hepatol 2019 Mar 21. Epub 2019 Mar 21.

Division of Gastroenterology, St. Luke's International University, Tokyo, Japan.

Background And Aim: The risk factors for early rebleeding following the management of colonic diverticular bleeding (CDB) are unclear. This study aimed to determine the risk factors for early rebleeding following initial colonoscopy.

Methods: Overall, 370 patients with CDB were divided as having presumptive (229) or definite CDB with stigmata of recent hemorrhage (141) based on initial colonoscopy. Read More

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http://dx.doi.org/10.1111/jgh.14669DOI Listing

Noneffectiveness of electroacupuncture for comorbid generalized anxiety disorder and irritable bowel syndrome.

J Gastroenterol Hepatol 2019 Mar 19. Epub 2019 Mar 19.

Institute of Digestive Disease, The Chinese University of Hong Kong, Shatin, Hong Kong.

Background And Aim: Comorbid generalized anxiety disorder and irritable bowel syndrome are common and therapeutically challenging. We aimed to assess the effectiveness of electroacupuncture in relieving anxiety and bowel symptoms in Chinese adults with this form of comorbidity.

Methods: In a single-blind randomized sham-controlled trial, subjects with comorbid generalized anxiety disorder and irritable bowel syndrome were randomly assigned to receive 10 weekly sessions of electroacupuncture or sham electroacupuncture. Read More

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http://dx.doi.org/10.1111/jgh.14667DOI Listing
March 2019
2 Reads

Establishment of gene-edited pigs expressing human blood-coagulation factor VII and albumin for bioartificial liver use.

J Gastroenterol Hepatol 2019 Mar 18. Epub 2019 Mar 18.

Department of Hepatobiliary Surgery II, Guangdong Provincial Research Center for Artificial Organ and Tissue Engineering, Institute of Regenerative Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, China.

Background And Aim: Bioartificial livers (BALs) are considered as a solution to bridge patients with acute liver failure to liver transplantation or to assist in spontaneous recovery for patients with end-stage liver disease. Pig is the best donor of hepatocytes for BALs in clinical trials, because metabolic and detoxification function of its liver are close to human. However, using pig hepatocytes for BALs remains controversial for safety concern owing to nonhuman proteins secretion. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jgh.14666
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http://dx.doi.org/10.1111/jgh.14666DOI Listing
March 2019
5 Reads
3.504 Impact Factor

Late-evening snacking improves liver functions in patients with liver cirrhosis: A meta-analysis of randomized controlled trials.

J Gastroenterol Hepatol 2019 Mar 18. Epub 2019 Mar 18.

Department of Nursing, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

Background And Aim: Reduce post-absorptive (fasting) phase by eating late-evening snacks (LES) is a potential intervention to improve substrate utilization and reverse sarcopenia. This study analyzed the results of published randomized control and controlled clinical trials to evaluate the effects of LES on liver function of patients with cirrhosis.

Methods: A meta-analysis was conducted. Read More

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http://dx.doi.org/10.1111/jgh.14665DOI Listing
March 2019
1 Read

Prevalence of pancreatic cystic lesions detected by magnetic resonance imaging in the Chinese population.

J Gastroenterol Hepatol 2019 Mar 18. Epub 2019 Mar 18.

Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai, China.

Background And Aim: Incidental pancreatic cystic lesions (PCLs) are being diagnosed more frequently. However, little is known about the prevalence of PCLs in the Chinese population. The aim of the study was to assess the crude prevalence of PCLs in individuals who underwent magnetic resonance imaging (MRI). Read More

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http://dx.doi.org/10.1111/jgh.14658DOI Listing

Pancreatic liposarcoma: A rare cause of pancreatic mass in adult.

Authors:
D Cao J Wang L Guo

J Gastroenterol Hepatol 2019 Mar 18. Epub 2019 Mar 18.

Department of Pathology, The First Hospital of Jilin University, Changchun, China.

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http://dx.doi.org/10.1111/jgh.14621DOI Listing

Vonoprazan versus proton-pump inhibitors for healing gastroesophageal reflux disease: A systematic review.

J Gastroenterol Hepatol 2019 Mar 18. Epub 2019 Mar 18.

Director's Office, Center for Medical Statistics, Tokyo, Japan.

Background And Aim: Gastroesophageal reflux disease (GERD) is a common disease caused by reflux of gastric contents to the esophagus. Proton-pump inhibitors (PPIs) are recommended as a first-line therapy to treat GERD. Recently, a new potassium-competitive acid blocker, vonoprazan, was launched in Japan. Read More

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http://dx.doi.org/10.1111/jgh.14664DOI Listing
March 2019
3 Reads

Gallbladder volvulus: A rare cause of acute gallbladder distension.

J Gastroenterol Hepatol 2019 Mar 14. Epub 2019 Mar 14.

Department of Surgery, Centre Hospitalier Avranches-Granville, Avranches, France.

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http://dx.doi.org/10.1111/jgh.14619DOI Listing
March 2019
1 Read

Serum C16:1n7/C16:0 ratio as a diagnostic marker for non-alcoholic steatohepatitis.

J Gastroenterol Hepatol 2019 Mar 12. Epub 2019 Mar 12.

Department of Gastroenterology, Graduate School of Medicine, Kanazawa University, Kanazawa, Japan.

Background And Aims: Accurate diagnosis of non-alcoholic steatohepatitis (NASH) from non-alcoholic fatty liver disease (NAFLD) is clinically important. Therefore, there is a need for easier ways of diagnosing NASH. In this study, we investigated the serum fatty acid composition and evaluated the possibility of using the serum fatty acid composition as a diagnostic marker of NASH. Read More

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http://dx.doi.org/10.1111/jgh.14654DOI Listing
March 2019
3 Reads

The safety of newly developed automatic temperature-controlled endobiliary radiofrequency ablation system for malignant biliary strictures: A prospective multicenter study.

J Gastroenterol Hepatol 2019 Mar 12. Epub 2019 Mar 12.

Digestive Disease Center and Research Institute, Department of Internal Medicine, Soonchunhyang University School of Medicine, Korea.

Background And Aims: Catheter-based endobiliary radiofrequency ablation (RFA) is an endoscopic local treatment for patients with malignant biliary stricture (MBS). However, excessive heating of the bile duct by the current RFA system can induce serious complications. Recently, a new RFA system with automatic temperature control was developed. Read More

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http://doi.wiley.com/10.1111/jgh.14657
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http://dx.doi.org/10.1111/jgh.14657DOI Listing
March 2019
10 Reads

Characteristics of acute hepatitis A virus infection before and after 2001: A hospital-based study in Tokyo, Japan.

J Gastroenterol Hepatol 2019 Mar 12. Epub 2019 Mar 12.

Institute of Gastroenterology, Department of Internal Medicine, Tokyo Women's Medical University, Tokyo, Japan.

Background And Aim: The incidence of acute hepatitis A [AH (A)] is decreasing because of improvements in hygiene; however, cases of sporadic severe hepatitis are still being reported. We assessed the epidemiology of AH (A) in Japan.

Methods: This was a hospital-based retrospective study, in which 126 AH (A) patients (96 men [76%], median age 39 [range, 19-66] years) were enrolled. Read More

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http://dx.doi.org/10.1111/jgh.14655DOI Listing
March 2019
2 Reads

Utility of the EncephalApp Stroop Test for covert hepatic encephalopathy screening in Chinese cirrhotic patients.

J Gastroenterol Hepatol 2019 Mar 12. Epub 2019 Mar 12.

Department of Gastroenterology, Peking University People's Hospital, Beijing, China.

Background And Aim: Considering the large size of the potential population and limitations of common detection methods, covert hepatic encephalopathy (CHE) is difficult to screen for routinely. The present study aims to explore EncephalApp Stroop Test as a smartphone-based CHE screening tool in China.

Methods: A multicenter, single-visit study was carried out. Read More

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http://dx.doi.org/10.1111/jgh.14656DOI Listing
March 2019
3 Reads

Urinary abnormalities in children and adolescents with Wilson disease before and during treatment with d-penicillamine.

J Gastroenterol Hepatol 2019 Mar 12. Epub 2019 Mar 12.

Pediatrics Department, Cairo University, Cairo, Egypt.

Background And Aim: Renal abnormalities can occur at any time point during the course of Wilson disease (WD). We aimed to fill a literature gap in this respect by studying urinary abnormalities in children and adolescents with WD.

Methods: This study included 60 children with WD presenting to the Pediatric Hepatology Unit, Cairo University. Read More

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http://dx.doi.org/10.1111/jgh.14653DOI Listing
March 2019
1 Read

ZNF133 is associated with infliximab responsiveness in patients with inflammatory bowel diseases.

J Gastroenterol Hepatol 2019 Mar 9. Epub 2019 Mar 9.

Department of Internal Medicine and Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Korea.

Background And Aim: Infliximab has been widely prescribed for treating inflammatory bowel disease (IBD). However, the response rates to infliximab differ among patients. Therefore, we aimed to identify the genetic and clinical markers that predict infliximab response. Read More

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http://dx.doi.org/10.1111/jgh.14652DOI Listing
March 2019
9 Reads

Clinical and psychological characteristics in gastroesophageal reflux disease patients overlapping with laryngopharyngeal reflux symptoms.

J Gastroenterol Hepatol 2019 Mar 8. Epub 2019 Mar 8.

Department of Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation and Tzu Chi University, Hualien, Taiwan.

Background And Aim: Laryngopharyngeal reflux (LPR) defined as reflux of gastric content reaching above the upper esophageal sphincter is frequently found in patients with gastroesophageal reflux disease (GERD). This study aimed to investigate clinical and psychological differences between GERD patients with or without LPR symptoms.

Methods: This study enrolled 303 consecutive patients with proton pump inhibitor treatment-naïve scheduled for upper endoscopy because of troublesome reflux symptoms and recognized as GERD by non-dyspepsia reflux disease questionnaire score. Read More

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http://dx.doi.org/10.1111/jgh.14651DOI Listing
March 2019
5 Reads
3.504 Impact Factor

Best practices on immunomodulators and biological agents for Ulcerative colitis and Crohn's disease in Asia.

J Gastroenterol Hepatol 2019 Mar 8. Epub 2019 Mar 8.

Concord Hospital, Gastroenterology and Liver Services, Sydney, New South Wales, Australia.

The Asia Pacific Working Group on Inflammatory Bowel Disease (IBD) was established in Cebu, Philippines, under the auspices of the Asian Pacific Association of Gastroenterology (APAGE) with the goal of improving IBD care in Asia. This consensus is carried out in collaboration with Asian Organization for Crohn's and Colitis (AOCC). With biological agents and biosimilars becoming more established, it is necessary to conduct a review on existing literature and establish a consensus on when and how to introduce biological agents and biosimilars in the conjunction with conventional treatments for ulcerative colitis (UC) and Crohn's disease (CD) in Asia. Read More

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http://dx.doi.org/10.1111/jgh.14648DOI Listing
March 2019
3 Reads
3.504 Impact Factor

MiR-876-3p regulates cisplatin resistance and stem cell-like properties of gastric cancer cells by targeting TMED3.

J Gastroenterol Hepatol 2019 Mar 6. Epub 2019 Mar 6.

Department of Gastrointestinal Surgery, Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.

Background And Aim: Gastric cancer (GC), a prevalent tumor, exerts a major economic burden, and we aimed to explore miR-876-3p's effects on GC and related mechanisms.

Methods: Cell viability was analyzed via CCK-8 and colony formation assay. Stem cell-like properties were examined via spheroid colony formation assay. Read More

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http://dx.doi.org/10.1111/jgh.14649DOI Listing
March 2019
1 Read

Hepatobiliary and Pancreatic: Sub-Glisson's capsule hepatic multiple nodular formations.

J Gastroenterol Hepatol 2019 Mar 4. Epub 2019 Mar 4.

Department of Medicine Area, Medical Oncology Unit, E.O. Galliera Hospital, Genova, Italy.

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http://dx.doi.org/10.1111/jgh.14618DOI Listing
March 2019
1 Read

Long-term efficacy and safety of CT-P13, a biosimilar of infliximab, in patients with inflammatory bowel disease: A retrospective multicenter study.

J Gastroenterol Hepatol 2019 Mar 3. Epub 2019 Mar 3.

Division of Gastroenterology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.

Background And Aim: A biosimilar of infliximab, CT-P13 (Remsima®) has the potential to reduce treatment costs and enhance access to biological therapy for inflammatory bowel disease (IBD) patients. However, long-term clinical data on its use for IBD treatment are currently sparse. We aimed to investigate the long-term efficacy and safety of CT-P13 therapy in a large, real-life IBD cohort. Read More

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http://dx.doi.org/10.1111/jgh.14645DOI Listing
March 2019
8 Reads

Chemoprevention of gastric cancer by Helicobacter pylori eradication and its underlying mechanism.

Authors:
Nayoung Kim

J Gastroenterol Hepatol 2019 Mar 3. Epub 2019 Mar 3.

Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.

The cascade of gastric cancer, a leading cause of cancer incidence and mortality, is multifactorial. Helicobacter pylori (HP) infection plays a major role in gastric cancer (GC), and there has been an accumulation of data regarding the chemopreventive effect of HP eradication. However, it remains unclear how HP infection causes GC and how HP eradication prevents GC. Read More

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http://doi.wiley.com/10.1111/jgh.14646
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http://dx.doi.org/10.1111/jgh.14646DOI Listing
March 2019
10 Reads
3.504 Impact Factor

Nivolumab-related pancreatitis with autoimmune pancreatitis-like imaging features.

J Gastroenterol Hepatol 2019 Mar 3. Epub 2019 Mar 3.

Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.

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http://dx.doi.org/10.1111/jgh.14620DOI Listing
March 2019
2 Reads

Searching for the link; mechanisms underlying liver regeneration and recurrence of colorectal liver metastasis post partial hepatectomy.

J Gastroenterol Hepatol 2019 Mar 3. Epub 2019 Mar 3.

Department of Surgery, Austin Health, University of Melbourne, Heidelberg, Victoria, Australia.

Despite excellent treatment of primary colorectal cancer, the majority of deaths occur as a result of metastasis to the liver. Recent population studies have estimated that one quarter of patients with colorectal cancer will incur synchronous or metachronous colorectal liver metastasis. However, only one quarter of these patients will be eligible for potentially curative resection. Read More

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http://dx.doi.org/10.1111/jgh.14644DOI Listing
March 2019
1 Read

Adipose tissue-derived stem cells prevent fibrosis in murine steatohepatitis by suppressing IL-17-mediated inflammation.

J Gastroenterol Hepatol 2019 Mar 3. Epub 2019 Mar 3.

Department of Disease Control and Homeostasis, College of Medical Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.

Background And Aim: The pathological features of non-alcoholic steatohepatitis (NASH) have not been determined, so fundamental treatment has not been established. Adipose-tissue-derived stromal/stem cells (ADSCs) are beneficial for repair/regenerative therapy of impaired organs because of their immuno-modulatory capability. In this study, we assessed how liver damage progresses during the early development phase of the murine NASH model and investigated whether ADSCs are preventatively efficacious against the fibrosis progression of NASH. Read More

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http://dx.doi.org/10.1111/jgh.14647DOI Listing
March 2019
2 Reads

Human amnion epithelial cells and their soluble factors reduce liver fibrosis in murine non-alcoholic steatohepatitis.

J Gastroenterol Hepatol 2019 Mar 1. Epub 2019 Mar 1.

Centre for Inflammatory Disease, School of Clinical Sciences at Monash Health, Monash University, Melbourne, Victoria, Australia.

Background And Aim: Non-alcoholic steatohepatitis (NASH) can lead to cirrhosis and hepatocellular carcinoma. Currently, lifestyle modification is the only effective treatment. We have shown that human amnion epithelial cells (hAECs) reduce inflammation and fibrosis in toxin-induced liver injury models. Read More

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http://dx.doi.org/10.1111/jgh.14643DOI Listing
March 2019
2 Reads

Association between dietary iron and zinc intake and development of ulcerative colitis: A case-control study in Japan.

J Gastroenterol Hepatol 2019 Mar 1. Epub 2019 Mar 1.

Department of Public Health, Osaka City University Graduate School of Medicine, Osaka, Japan.

Background And Aim: The prevalence of ulcerative colitis (UC) has been increasing in Japan. Trace elements, such as iron, zinc, magnesium, and copper, can cause digestive symptoms where there is a deficiency or excess. We focused on the dietary intake of trace elements and their associations with UC development. Read More

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http://dx.doi.org/10.1111/jgh.14642DOI Listing

When the balloon goes up ….

Authors:
Tiing Leong Ang

J Gastroenterol Hepatol 2019 Mar;34(3):483-484

Department of Gastroenterology and Hepatology, Changi General Hospital, and Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

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http://dx.doi.org/10.1111/jgh.14633DOI Listing
March 2019
4 Reads

Call for a close collaborations between bioengineers and gastroenterologist.

Authors:
H Gregersen

J Gastroenterol Hepatol 2019 Mar;34(3):479-480

Prince of Wales Hospital, The Chinese University of Hong Kong, Department of Surgery.

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http://dx.doi.org/10.1111/jgh.14628DOI Listing
March 2019
1 Read

Recent advances in the management of hepatocellular carcinoma: First, cut … is the deepest or is it "no-touch" and exercise?

Authors:
Narci C Teoh

J Gastroenterol Hepatol 2019 Mar;34(3):481-482

Gastroenterology and Hepatology Unit and The Australian National University Medical School, The Canberra Hospital, Canberra, Australian Capital Territory, Australia.

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http://dx.doi.org/10.1111/jgh.14632DOI Listing
March 2019
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The clinicopathological differences of sporadic non-ampullary duodenal epithelial neoplasm depending on tumor location.

J Gastroenterol Hepatol 2019 Feb 27. Epub 2019 Feb 27.

Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.

Background And Aim: Although sporadic non-ampullary duodenal adenoma is speculated to be precancerous lesion, the relationship between adenoma and carcinoma remains unclear due to their rarity. Previous studies on sporadic non-ampullary duodenal epithelial neoplasm (SNADEN) have mainly targeted superficial tumors, like adenoma and early carcinoma. The clinicopathological features, including those of advanced carcinoma, remain poorly investigated. Read More

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http://dx.doi.org/10.1111/jgh.14640DOI Listing
February 2019
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Gastrointestinal: Extensive abdominal involvement as an initial presentation of Langerhans' cell histiocytosis.

J Gastroenterol Hepatol 2019 Feb 27. Epub 2019 Feb 27.

Department of Pathology, University of Pamukkale, Denizli, Turkey.

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http://dx.doi.org/10.1111/jgh.14598DOI Listing
February 2019
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Eradication rate of Helicobacter pylori reinfection in Korea: A retrospective study.

J Gastroenterol Hepatol 2019 Feb 27. Epub 2019 Feb 27.

Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Background And Aim: Guidelines for selecting the eradication regimen for Helicobacter pylori reinfection remain unclear. This study aimed to evaluate the eradication rate of H. pylori reinfection in patients with a previous infection successfully eradicated with index triple therapy. Read More

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http://dx.doi.org/10.1111/jgh.14639DOI Listing
February 2019

Serum Mac-2-binding protein glycosylation isomer and risk of hepatocellular carcinoma in entecavir-treated chronic hepatitis B patients.

J Gastroenterol Hepatol 2019 Feb 20. Epub 2019 Feb 20.

Department of Medicine, Queen Mary Hospital, Hong Kong.

Background And Aim: Hepatocellular carcinoma (HCC) can still develop in chronic hepatitis B (CHB) patients receiving antiviral treatment. Serum Mac-2-binding protein glycosylation isomer (M2BPGi) is a novel marker for liver fibrosis. We investigated its role on incidence of HCC in entecavir (ETV)-treated CHB patients. Read More

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http://doi.wiley.com/10.1111/jgh.14637
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http://dx.doi.org/10.1111/jgh.14637DOI Listing
February 2019
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