2,716 results match your criteria Journal of Clinical and Experimental Neuropsychology[Journal]


Temperament, executive function, and attention-deficit/hyperactivity disorder (ADHD) in adolescents: The mediating role of effortful control.

J Clin Exp Neuropsychol 2019 Apr 21:1-19. Epub 2019 Apr 21.

a Department of Clinical Psychology and Psychobiology, Faculty of Psychology , University of Barcelona , Barcelona , Spain.

Introduction: Temperament dimensions may be related to executive functions (EF) and may be involved in the expression and maintenance of symptoms of attention-deficit/hyperactivity disorder (ADHD). The current study aimed to assess whether effortful control (EC) mediates the relationship between EF and inattentive symptoms, and whether surgency (S) and negative affectivity (NA) mediate the relationships between EF and hyperactive-impulsive ADHD symptoms in adolescents.

Method: Working individually, participants aged between 12 and 16 years (N = 118; 75 with ADHD) performed tests of cognitive EF (working memory, planning, flexibility, and inhibition), and parents and teachers completed a multi-informant assessment focusing on measures of ADHD symptoms and temperament dimensions (EC, S, and NA). Read More

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http://dx.doi.org/10.1080/13803395.2019.1599824DOI Listing

What a pooled data study tells us about the relationships between gender and knowledge of semantic categories.

J Clin Exp Neuropsychol 2019 Apr 17:1-10. Epub 2019 Apr 17.

b Institute of Neurology , IRCCS Fondazione Policlinico Universitario "A. Gemelli & UCSC Catholic University , Rome , Italy.

Introduction: Both the neuropsychological study of patients with category-specific semantic disorders (CSSD) and the experimental research on categorical processing in healthy subjects (HSs) have shown that men are mainly impaired with fruits and vegetables and women with animals and artifacts. Since this difference is more striking in patients with CSSD than in HSs, we hypothesized that the lack of power of some investigations conducted with HSs and the different methods used in studies conducted with HSs and patients with CSSD could explain some of these inconsistencies and that a study conducted with a very large number of HSs using visual naming tasks should strongly confirm the role of gender in categorical tasks.

Methods: Picture naming data gathered during the last ten years with our category-specificity paradigm from a large number (702) of HSs were reanalyzed. Read More

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http://dx.doi.org/10.1080/13803395.2019.1602111DOI Listing

Subjective ratings of cognitive and emotional functioning in patients with mild cognitive impairment and patients with subjective memory complaints but normal cognitive functioning.

J Clin Exp Neuropsychol 2019 Apr 8:1-11. Epub 2019 Apr 8.

b Department of Clinical Neuropsychology , Barrow Neurological Institute , Phoenix , AZ , USA.

In a retrospective chart review, 39 patients referred for a clinical neuropsychological examination were identified as showing either mild cognitive impairment of the amnestic type (MCI-A; N = 21) or subjective memory complaints but with normal memory function (SMC; N = 18). During the clinical interview, patients and informants were routinely asked to make subjective ratings regarding the patient's cognitive and affective functioning in everyday life. The purpose of this study was to determine whether these two patient groups (and their informants) significantly differed in their subjective reports about level of cognitive and affective difficulties. Read More

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http://dx.doi.org/10.1080/13803395.2019.1588229DOI Listing
April 2019
1 Read

Sensitivity of a Preclinical Alzheimer's Cognitive Composite (PACC) to amyloid β load in preclinical Alzheimer's disease.

J Clin Exp Neuropsychol 2019 Mar 29:1-10. Epub 2019 Mar 29.

a The Florey Institute of Neuroscience and Mental Health , The University of Melbourne , Melbourne , VIC , Australia.

Introduction: Preclinical Alzheimer's disease (AD) is characterized by amyloid-related cognitive decline. Reduction in this decline is used to determine the efficacy of drug therapies designed to forestall the disease in preclinical AD clinical trials, measured by a Preclinical Alzheimer's Cognitive Composite (PACC). Most studies estimate rates of cognitive change by comparing cognitively normal (CN) older adults with abnormally high beta-amyloid (Aβ+) to those with low levels (Aβ-). Read More

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http://dx.doi.org/10.1080/13803395.2019.1593949DOI Listing
March 2019
2 Reads

Semantic processing in children with cochlear implants: Evidence from event-related potentials.

J Clin Exp Neuropsychol 2019 Mar 28:1-15. Epub 2019 Mar 28.

a School of Health and Rehabilitation Sciences , The University of Queensland , St Lucia , QLD , Australia.

Introduction: Existing research has shown that children with significant hearing loss who use cochlear implants (CIs) perform worse than their hearing peers on behavioral measures of spoken language. The present study sought to examine how children with CIs process lexical-semantic incongruence, as indexed by electrophysiological evidence of the N400 effect.

Method: Twelve children with CIs, aged between 6 and 9 years, participated in a spoken word-picture matching task while event-related potentials (ERPs) were recorded. Read More

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http://dx.doi.org/10.1080/13803395.2019.1592119DOI Listing

The Titrated Monetary Incentive Delay Task: Sensitivity, convergent and divergent validity, and neural correlates in an RDoC sample.

J Clin Exp Neuropsychol 2019 Mar 26:1-18. Epub 2019 Mar 26.

e Department of Psychiatry , University of Utah , Salt Lake County , Salt Lake City, UT , USA.

Introduction: Neuropsychological tests are designed to assay brain function via performance measurements. Many tests corresponding to visual and motor cortex function have been validated. Tests probing reward circuitry, including the ventral striatum (VS), could benefit assessment of numerous neurological and psychiatric disorders in which reward or VS function is disturbed. Read More

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http://dx.doi.org/10.1080/13803395.2019.1585519DOI Listing
March 2019
1 Read

Smell your memories: Positive effect of odor exposure on recent and remote autobiographical memories in Alzheimer's disease.

J Clin Exp Neuropsychol 2019 Mar 19:1-10. Epub 2019 Mar 19.

d Unité de Gériatrie, Centre Hospitalier de Tourcoing , Tourcoing , France.

Introduction: There is a burgeoning interest in the effects of odor exposure on autobiographical memory in Alzheimer's disease (AD). We pursued this line of research by assessing the effect of odor exposure on the retrieval of recent and remote memories in AD.

Method: Twenty-six patients with mild AD and 28 controls were tested in two conditions: with and without odor exposure. Read More

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http://dx.doi.org/10.1080/13803395.2019.1586840DOI Listing

Single-photon emission computed tomography (SPECT) perfusion and neuropsychological performance in mild cognitive impairment.

J Clin Exp Neuropsychol 2019 Mar 18:1-14. Epub 2019 Mar 18.

a Department of Psychiatry and Human Behavior, Warren Alpert Medical School , Brown University , Providence , RI , USA.

Single-photon emission computed tomography (SPECT) is an affordable neuroimaging technique that measures cerebral perfusion and has been utilized repeatedly in aging populations. However, we are aware of no studies to date examining relationships between SPECT imaging and comprehensive neuropsychological evaluations in a clinical sample of patients with mild cognitive impairment (MCI). Participants were 124 older adults with MCI (age, M = 75. Read More

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http://dx.doi.org/10.1080/13803395.2019.1586838DOI Listing
March 2019
4 Reads

Postconcussion symptom reporting is not associated with diffusion tensor imaging findings in the subacute to chronic phase of recovery in military service members following mild traumatic brain injury.

J Clin Exp Neuropsychol 2019 Mar 14:1-15. Epub 2019 Mar 14.

a Defense and Veterans Brain Injury Center , Walter Reed National Military Medical Center , Bethesda , MD , USA.

Introduction: The purpose of this study was to examine the relation between white matter integrity of the brain and postconcussion symptom reporting following mild traumatic brain injury (MTBI).

Method: Participants were 109 U.S. Read More

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http://dx.doi.org/10.1080/13803395.2019.1585518DOI Listing

Differences in self-awareness of functional deficits between amnestic single- and multidomain mild cognitive impairment.

J Clin Exp Neuropsychol 2019 Mar 14:1-10. Epub 2019 Mar 14.

b Department of Medicine , University of Alabama at Birmingham , Birmingham , AL , USA.

Introduction: Prior research examining self-awareness of deficits in those with mild cognitive impairment (MCI) has been inconsistent, suggesting that preservation of insight at this disease stage may be conditional on the domain(s) examined as well as individual characteristics. The current study is the first to examine differences in objective performance and self-awareness of difficulties between older adults with amnestic single- (MCI-ASD) and multidomain MCI (MCI-AMD) across six instrumental activities of daily living (IADLs).

Method: Seventy-five individuals (M = 73. Read More

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http://dx.doi.org/10.1080/13803395.2019.1586839DOI Listing
March 2019
2 Reads

Decision support in patients with mild Alzheimer's disease.

J Clin Exp Neuropsychol 2019 Mar 5:1-13. Epub 2019 Mar 5.

a General Psychology: Cognition and Center for Behavioral Addiction Research (CeBAR) , University of Duisburg-Essen , Duisburg , Germany.

Introduction: Making advantageous decisions is a key competence of individuals of all ages. However, previous studies reported a reduction of this competence in patients with neurodegenerative diseases such as Alzheimer's disease, which is explained by impairments of executive functions such as cognitive flexibility or working memory. While previous findings from healthy participants with reduced executive functions showed that support can improve decision making under risk, the study at hand aimed to investigate this effect in patients with mild Alzheimer's disease (mAD). Read More

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http://dx.doi.org/10.1080/13803395.2019.1585517DOI Listing
March 2019
1 Read

Performance validity measures in clinical patients with aphasia.

J Clin Exp Neuropsychol 2019 Feb 22:1-8. Epub 2019 Feb 22.

a Department of Neurology , Medical University of Innsbruck , Innsbruck , Austria.

Introduction: Performance validity testing has developed into an indispensible element of neuropsychological assessment, mostly applied in forensic determinations. Its aim is to distinguish genuine patient performance from invalid test profiles. Limits to the applicability of performance validity tests (PVTs) may arise when genuine cognitive symptoms are present. Read More

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http://dx.doi.org/10.1080/13803395.2019.1579783DOI Listing
February 2019
3 Reads

Validity of an eyetracking method for capturing auditory-visual cross-format semantic priming.

J Clin Exp Neuropsychol 2019 May 6;41(4):411-431. Epub 2019 Feb 6.

b Springfield College , Springfield, Massachusetts , MA , USA.

Introduction: Semantic priming paradigms are important for understanding lexical-semantic processing and the nature of linguistic deficits accompanying language performance in neurologically impaired individuals such as people with aphasia. Reaction-time-(RT)-based traditional semantic priming tasks entail potential confounds, especially problematic when applied to people with aphasia, who may have concomitant neurocognitive challenges that limit task performance. Some of these confounds include requirements of following complex instructions, making metalinguistic judgments, and using speech or limb-based motor actions to indicate overt responses. Read More

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http://dx.doi.org/10.1080/13803395.2019.1567692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428604PMC
May 2019
2 Reads

Visuospatial neglect is more severe when stimulus density is large.

J Clin Exp Neuropsychol 2019 May 6;41(4):399-410. Epub 2019 Feb 6.

a Experimental Psychology, Helmholtz Institute , Utrecht University , Utrecht , the Netherlands.

Patients with visuospatial neglect (VSN) suffer from an imbalance in visual attention between their left and right (egocentric or allocentric) hemispace. The view of VSN as an attentional imbalance between two hemispaces ignores the fact that-in our daily life-we are presented with varying levels of stimulus density, within but also across hemispaces. Therefore, we developed a novel experimental paradigm in which stroke patients (n = 207) were presented with a different number of simple objects in the left and right (egocentric) hemispaces and were asked to indicate whether there were more objects in the left or the right hemispace. Read More

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http://dx.doi.org/10.1080/13803395.2019.1566444DOI Listing
May 2019
5 Reads

Regression-based formulas for predicting change in memory test scores in healthy older adults: Comparing use of raw versus standardized scores.

J Clin Exp Neuropsychol 2019 Feb 5:1-9. Epub 2019 Feb 5.

a Neuropsychology , Cleveland Clinic Lou Ruvo Center for Brain Health , Las Vegas , NV , USA.

Introduction: Standardized regression based (SRB) methods can be used to determine whether meaningful changes in performance on cognitive assessments occur over time. Both raw and standardized scores have been used in SRB models but it is unclear which score metric is most appropriate for predicting follow-up performance. The aim of the present study was to examine differences in SRB prediction formulas using raw versus standard scores on two memory tests commonly used in assessment of older adults. Read More

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https://www.tandfonline.com/doi/full/10.1080/13803395.2019.1
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http://dx.doi.org/10.1080/13803395.2019.1571169DOI Listing
February 2019
1 Read

A novel unstructured performance-based task of executive function in children with attention-deficit/hyperactivity disorder.

J Clin Exp Neuropsychol 2019 Feb 4:1-15. Epub 2019 Feb 4.

a Psychology , York University , Toronto , ON , Canada.

Objective: Executive functions (EFs) have been assessed with performance-based measures and rating scales. Research has shown a lack of association between these two methods. One factor that might contribute to this difference is the structure provided on performance-based measures that is not provided on rating scales. Read More

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http://dx.doi.org/10.1080/13803395.2019.1567694DOI Listing
February 2019
1 Read

Cognitive deficits in progressive supranuclear palsy on the Repeatable Battery for the Assessment of Neuropsychological Status.

J Clin Exp Neuropsychol 2019 Feb 4:1-7. Epub 2019 Feb 4.

b Memory and Aging Center, Department of Neurology , University of California , San Francisco , CA, USA.

Progressive supranuclear palsy (PSP) is associated with a variety of cognitive deficits, as well as motor and psychiatric disturbances. As clinical trials for PSP evolve, briefer screening instruments will be needed to determine cognitive effects of interventions. The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) may fill this gap. Read More

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http://dx.doi.org/10.1080/13803395.2019.1572073DOI Listing
February 2019

Neurobehavioral symptom validity in U.S. Department of Veterans Affairs (VA) mild traumatic brain injury evaluations.

Authors:
Lee Ashendorf

J Clin Exp Neuropsychol 2019 May 4;41(4):432-441. Epub 2019 Feb 4.

a Department of Psychiatry , University of Massachusetts Medical School , Worcester , MA , USA.

Introduction: The use of the Neurobehavioral Symptom Inventory (NSI) by U.S. Department of Defense and Veterans Affairs (VA) providers for all mild traumatic brain injury (mTBI) evaluations led to the development of methods to screen for symptom exaggeration. Read More

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http://dx.doi.org/10.1080/13803395.2019.1567693DOI Listing
May 2019
1 Read

Impact of perceived stress on cognitive performance: Moderating effect of mild cognitive impairment and Alzheimer's disease.

J Clin Exp Neuropsychol 2019 May 29;41(4):364-379. Epub 2019 Jan 29.

c Laboratory Epsylon EA 4556 , Université of Montpellier and University Paul Valéry , Montpellier , France.

Introduction: Stress is a well-known determinant of cognitive performance in both younger and older adults. However, the moderating effect of pathological aging on this relationship remains insufficiently documented. We hypothesize that mild cognitive impairment (MCI) and Alzheimer's disease (AD) patients will report higher perceived stress than control older adults, when asked to complete an effortful cognitive task. Read More

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http://dx.doi.org/10.1080/13803395.2018.1564250DOI Listing
May 2019
14 Reads

Coping style as a protective factor for emotional consequences of structural neuropathology in multiple sclerosis.

J Clin Exp Neuropsychol 2019 May 24;41(4):390-398. Epub 2019 Jan 24.

b Department of Psychology , Pennsylvania State University , University Park , PA , USA.

Introduction: In people with multiple sclerosis (MS), depression symptoms could be a direct consequence of neuropathological processes or a secondary consequence of coping with debilitating illness. We investigated the interaction of white matter structure and patient coping style in predicting positive and negative emotion symptoms of depression.

Method: Participants completed a neuropsychological battery, including the Chicago Multiscale Depression Inventory (CMDI) and a measure of coping strategies that has Active Coping (more adaptive) and Avoidant Coping (less adaptive) scales. Read More

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https://www.tandfonline.com/doi/full/10.1080/13803395.2019.1
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http://dx.doi.org/10.1080/13803395.2019.1566443DOI Listing
May 2019
7 Reads

Validity of the Verbal Concept Attainment Test in multiple sclerosis.

J Clin Exp Neuropsychol 2019 May 14;41(4):331-340. Epub 2019 Jan 14.

d Department of Psychiatry , The Ohio State University , Columbus , OH.

Objective: As many as 70% of people with multiple sclerosis (MS) have clinically significant cognitive impairment, and most of these individuals exhibit executive dysfunction. Most research concerning executive dysfunction in MS has focused upon nonverbal measures. The Verbal Concept Attainment Test (VCAT) has demonstrated construct validity as an executive function measure in people infected with HIV and in people with focal brain lesions, but its validity among people with MS is unknown. Read More

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http://dx.doi.org/10.1080/13803395.2018.1562048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428607PMC
May 2019
1 Read

Emotion and decision-making: Induced mood influences IGT scores and deck selection strategies.

J Clin Exp Neuropsychol 2019 May 11;41(4):341-352. Epub 2019 Jan 11.

a Department of Psychology , University of Massachusetts Boston , Boston , MA , USA.

The somatic marker hypothesis (SMH) represents a rich neuropsychological framework to study emotion-based decision-making. It originates from early brain lesion studies using the Iowa Gambling Task (IGT), which showed that adaptive decision-making relies on intact ventromedial prefrontal cortex for the integration of so-called "hot" affective signals and rational "cold" perceptual cognitive computations. Subsequent studies over the past 20 years have provided converging evidence for the reliability and validity of the IGT in assessing decision-making in both healthy and clinical samples, although some discrepancies remain. Read More

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https://www.tandfonline.com/doi/full/10.1080/13803395.2018.1
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http://dx.doi.org/10.1080/13803395.2018.1562049DOI Listing
May 2019
16 Reads

Alzheimer's disease and the processing of uncertainty during choice task performance: Executive dysfunction within the Hick-Hyman law.

J Clin Exp Neuropsychol 2019 May 11;41(4):380-389. Epub 2019 Jan 11.

b Department of Cognitive, Linguistic, and Psychological Sciences , Brown University , Providence , RI , USA.

The Hick-Hyman law states that choice response time (RT) increases linearly with increasing information uncertainty. Neuroimaging studies suggest that the representation of uncertainty in support of response generation is mediated by the cognitive control network (CCN), which is disrupted in Alzheimer's disease (AD). Thus, we predicted that patients with AD would be sensitive to increased uncertainty particularly under conditions that place demands on the internal representation of uncertainty, and that choice RT performance under these conditions would be associated with performance on tests of executive function. Read More

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http://dx.doi.org/10.1080/13803395.2018.1564813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428614PMC
May 2019
13 Reads

Selection for sentence generation in the context of severe anomia: A case series of left temporal patients.

J Clin Exp Neuropsychol 2019 May 4;41(4):353-363. Epub 2019 Jan 4.

a Neuropsychology Research Unit, School of Psychology , The University of Queensland , Brisbane , QLD , Australia.

Introduction: Anomia is an impairment of naming: the retrieval of specific lexical items from the mental lexicon. Theoretically, whether anomia reflects a failure of selection at the preverbal "idea" level or at the subsequent linguistic formulation stage remains a topic of debate. We investigated the preverbal mechanism of idea selection for sentence generation, which requires the selection of a proposition from among competing alternatives during message formulation, in patients with severe anomia. Read More

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http://dx.doi.org/10.1080/13803395.2018.1562050DOI Listing
May 2019
1 Read

Characterization of inhibitory failure in Multiple Sclerosis: Evidence of impaired conflict resolution.

J Clin Exp Neuropsychol 2019 Apr 10;41(3):320-329. Epub 2018 Dec 10.

a School of Psychological Sciences and Monash Institute of Cognitive and Clinical Neurosciences , Monash University , Clayton , Victoria , Australia.

Introduction: Inhibitory control deficits are frequently reported in Multiple Sclerosis (MS), although it is unclear whether these deficits represent a global or process-specific failure. Notably, most models of inhibitory control recognize at least two dissociable processes, the most consistent being: (a) the inhibition of a dominant response: response suppression, and (b) the inhibition of a dominant response and initiation of a nondominant response: executive control. This study aimed to ascertain the processes underlying inhibitory failure in MS. Read More

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http://dx.doi.org/10.1080/13803395.2018.1552756DOI Listing
April 2019
1 Read

Risky sexual behavior among adolescents: The role of decision-making, problems from cannabis use and externalizing disorder symptoms.

J Clin Exp Neuropsychol 2019 Apr 6;41(3):300-311. Epub 2018 Dec 6.

b Center for Children and Families , Florida International University , Miami , FL, USA.

Introduction: Previous research has demonstrated that externalizing symptoms, cannabis use problems, and poor decision-making abilities are each independently related to risky sexual behavior (RSB). However, few studies have examined the joint effect of these factors on RSB among a sample of adolescents.

Methods: The current study addresses this gap in the literature by examining how externalizing disorder symptoms, cannabis use, and decision-making abilities interact to predict RSB among a sample of adolescents (n = 204; M = 15. Read More

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https://www.tandfonline.com/doi/full/10.1080/13803395.2018.1
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http://dx.doi.org/10.1080/13803395.2018.1550192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404745PMC
April 2019
18 Reads

Financial incentives influence ImPACT validity indices but not cognitive composite scores.

J Clin Exp Neuropsychol 2019 Apr 5;41(3):312-319. Epub 2018 Dec 5.

c Department of Psychology , Penn State University , University Park , PA , USA.

Introduction: Interpreting change in cognitive performance across baseline and post-concussion evaluations is complicated by poor understanding of how incentives, such as return-to-play, may impact performance. This study examines the influence of an anticipated financial incentive on two sets of outcomes from the ImPACT computerized battery: (a) cognitive composites, meant to serve as measures of cognitive function, and (b) validity indices, proposed as indicators of invalid performance.

Method: 81 uninjured college students, randomized into two groups, completed a concussion assessment battery including ImPACT. Read More

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https://www.tandfonline.com/doi/full/10.1080/13803395.2018.1
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http://dx.doi.org/10.1080/13803395.2018.1551519DOI Listing
April 2019
16 Reads

Cognitive impairment following chemotherapy for breast cancer: The impact of practice effect on results.

J Clin Exp Neuropsychol 2019 Apr 26;41(3):290-299. Epub 2018 Nov 26.

d Department of Oncology , Consorci Sanitari de Terrassa (CST), Terrassa , Barcelona , Spain.

Chemotherapy-Related Cognitive Impairment (CRCI) can be an adverse effect in women treated for breast cancer. Some longitudinal studies reported deficits in attention, memory, and executive function following treatment, but other studies did not find cognitive changes. It is known that practice effects (PE) on repeated assessments with cognitive tests contribute to the discrepancies in these results, but its influence on scores has not been systematically explored. Read More

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http://dx.doi.org/10.1080/13803395.2018.1546381DOI Listing
April 2019
4 Reads

Multiple object tracking and pupillometry reveal deficits in both selective and intensive attention in unilateral spatial neglect.

J Clin Exp Neuropsychol 2019 Apr 14;41(3):270-289. Epub 2018 Nov 14.

b Department of Psychology , University of Oslo , Oslo , Norway.

Introduction: Unilateral spatial neglect is typically associated with a spatial attention deficit, as neglect patients fail to respond to objects in their contralesional hemispace. However, growing evidence suggests that also nonspatial attention impairments (e.g. Read More

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http://dx.doi.org/10.1080/13803395.2018.1536735DOI Listing
April 2019
5 Reads

Does stroke impair academic achievement in children? The role of metacognition in math and spelling outcomes following pediatric stroke.

J Clin Exp Neuropsychol 2019 Apr 23;41(3):257-269. Epub 2018 Oct 23.

a Department of Psychology , York University , Toronto , ON , Canada.

Introduction: Current research suggests that pediatric stroke is associated with a reduction in intellectual functioning. However, less is known about academic achievement and the contribution of specific executive functions to math and literacy in this population. The current study investigates behavioral ratings of executive functioning and their relationship to math and spelling performance in children with a history of unilateral arterial ischemic stroke. Read More

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http://dx.doi.org/10.1080/13803395.2018.1533528DOI Listing
April 2019
1 Read

Assessment of neuropsychological performance in Mexico City youth using the Cambridge Neuropsychological Test Automated Battery (CANTAB).

J Clin Exp Neuropsychol 2019 Apr 18;41(3):246-256. Epub 2018 Oct 18.

c Subdirección de Investigación en Intervenciones Comunitarias , Instituto Nacional de Perinatología , Mexico City , Mexico.

Background: The Cambridge Neuropsychological Test Automated Battery (CANTAB) is a computerized tool used to measure cognitive function in diverse populations and is sensitive for assessing developmental changes in children. Although CANTAB has been used in several countries, its applicability in a Mexican child population is unknown. This study examined developmental trends on CANTAB in a large sample of urban Mexico City youth and tested the hypothesis that their performance would be similar to a large US normative sample. Read More

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https://www.tandfonline.com/doi/full/10.1080/13803395.2018.1
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http://dx.doi.org/10.1080/13803395.2018.1529229DOI Listing
April 2019
24 Reads

Five-year change scores in old age for six neuropsychological tests and normative data for the Useful Field of View (UFOV) test: The influence of physical health.

J Clin Exp Neuropsychol 2019 Apr 18;41(3):229-245. Epub 2018 Oct 18.

a Function Area Aging Health and Functioning , Karolinska University Hospital , Stockholm , Sweden.

Introduction: Neuropsychological assessment of cognitive change over time is often conducted in clinical settings, but whether neuropsychological change scores are influenced by physical health has, as far as we know, not been examined previously.

Method: In a sample of 153 older Swedish adults (age range, 72-86 years), we evaluated the influence of common age-related diseases, terminal decline pathology, age, education, and gender, to provide (a) preliminary test-specific regression weights and 90% confidence intervals to assess significant change in performance after five years on tests of visual scanning, mental shifting, visual spatial ability, memory, reaction time, and selective attention, and (b) normative data for the Useful Field of View test (UFOV) from a single testing occasion.

Results: Multiple regression analyses showed that test-retest changes were affected by physical health for mental shifting, visual spatial ability, memory, and reaction time, by age for mental shifting and visual reaction time, by education for visual spatial ability, and by Age × Education for auditory reaction time. Read More

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http://dx.doi.org/10.1080/13803395.2018.1527292DOI Listing
April 2019
1 Read

Repeated computerized cognitive testing: Performance shifts and test-retest reliability in healthy older adults.

J Clin Exp Neuropsychol 2018 Oct 15:1-13. Epub 2018 Oct 15.

a Department of Psychology and Brain Health Research Centre , University of Otago , Dunedin , New Zealand.

Introduction: Repeated cognitive assessment is frequently required to monitor changes in cognitive functioning in older adults, but studies of repeated computerized testing in this population are scarce. To provide new insight into retest effects this study examined within- and between-day performance shifts and test-retest reliability among healthy older adults for test scores from a computerized cognitive battery.

Method: Thirty older men (65-71 years) completed the battery six times. Read More

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https://www.tandfonline.com/doi/full/10.1080/13803395.2018.1
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http://dx.doi.org/10.1080/13803395.2018.1526888DOI Listing
October 2018
6 Reads

Neuropsychological predictors of patient-reported cognitive decline after deep brain stimulation in Parkinson's disease.

J Clin Exp Neuropsychol 2019 Apr 8;41(3):219-228. Epub 2018 Oct 8.

a Department of Neurology , The Johns Hopkins University School of Medicine , Baltimore , MD , USA.

Background: Deep brain stimulation (DBS) is effective for treatment of motor complications of dopaminergic therapy in Parkinson's disease (PD) but occasionally has been associated with multidomain cognitive decline. Patient- and caregiver-reported cognitive decline are clinically meaningful and increasingly recognized as important to consider when evaluating therapeutic interventions for PD.

Objective: The objective was to assess presurgical neuropsychological and clinical factors associated with PD patient- and caregiver-reported cognitive decline in two or more domains after DBS. Read More

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http://dx.doi.org/10.1080/13803395.2018.1526889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380950PMC
April 2019
2 Reads

Face-to-trait inferences in patients with Parkinson's disease.

J Clin Exp Neuropsychol 2018 Sep 10:1-9. Epub 2018 Sep 10.

d Division of Neurology , Jichi Medical University , Tochigi , Japan.

Introduction: Parkinson's disease is a progressive neurological disorder characterized by the preferential loss of dopaminergic neurons in the substantia nigra, which project to the striatum. The disease is characterized by prominent motor symptoms, which are its cardinal features. Consequently, Parkinson's disease has been primarily considered a disorder of movement. Read More

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http://dx.doi.org/10.1080/13803395.2018.1513452DOI Listing
September 2018
6 Reads

False memories in patients with mild cognitive impairment and mild Alzheimer's disease dementia: Can cognitive strategies help?

J Clin Exp Neuropsychol 2018 Sep 4:1-15. Epub 2018 Sep 4.

a Center for Translational Cognitive Neuroscience , VA Boston Healthcare System , Boston , MA , USA.

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that presents predominantly with impairments in learning and memory. Patients with AD are also susceptible to false memories, a clinically relevant memory distortion where a patient remembers an incorrect memory that they believe to be true. The use of cognitive strategies to improve memory performance among patients with AD by reducing false memories has taken on added importance given the lack of disease-modifying agents for AD. Read More

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http://dx.doi.org/10.1080/13803395.2018.1513453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399077PMC
September 2018
6 Reads

Explicit and implicit memory for music in healthy older adults and patients with mild Alzheimer's disease.

J Clin Exp Neuropsychol 2018 Sep 3:1-12. Epub 2018 Sep 3.

b Center for Translational Cognitive Neuroscience , VA Boston Healthcare System , Boston , MA , USA.

Introduction: Previous studies have found that music paired with lyrics at encoding may improve the memory performance of patients with mild Alzheimer's disease (AD). To further explore memory for different types of musical stimuli, the current study examined both implicit and explicit memory for music with and without lyrics compared to spoken lyrics.

Method: In this mixed design, patients with probable mild AD (n = 15) and healthy older adults (n = 13) listened to auditory clips (song, instrumental, or spoken lyrics varied across three sessions) and then had their memory tested. Read More

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http://dx.doi.org/10.1080/13803395.2018.1510904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397787PMC
September 2018
1 Read

Perceptions of the cognitive effects of cannabis use: A survey of neuropsychologists' beliefs.

J Clin Exp Neuropsychol 2018 Aug 20:1-14. Epub 2018 Aug 20.

a Department of Psychology , Palo Alto University , Palo Alto , CA , USA.

Introduction: Research evaluating the neuropsychological effects of cannabis has yielded mixed findings, with some studies finding cognitive deficits in cannabis users (primarily in learning and memory) and others finding no significant effects. It is important to understand how clinicians perceive this discrepancy in the empirical literature. However, no studies have assessed neuropsychologists' beliefs regarding the effects of cannabis on cognitive functioning. Read More

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http://dx.doi.org/10.1080/13803395.2018.1503644DOI Listing
August 2018
34 Reads

Apolipoprotein E (APOE) ε4 genotype is associated with reduced neuropsychological performance in military veterans with a history of mild traumatic brain injury.

J Clin Exp Neuropsychol 2018 Dec 20;40(10):1050-1061. Epub 2018 Aug 20.

a VA San Diego Healthcare System (VASDHS) , San Diego , CA , USA.

Introduction: The purpose of this study was to investigate the effect of the apolipoprotein E (APOE) ε4 allele on neuropsychological functioning in military Veterans with a remote history of mild traumatic brain injury (mTBI).

Method: This cross-sectional study included 99 Veterans (mTBI = 53; military controls, MC = 46) who underwent neuropsychological assessment and APOE genotyping. Three neurocognitive composite scores-memory (α = . Read More

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http://dx.doi.org/10.1080/13803395.2018.1508555DOI Listing
December 2018
15 Reads

Intraindividual variability in neurocognitive performance: No influence due to HIV status or self-reported effort.

J Clin Exp Neuropsychol 2018 Dec 20;40(10):1044-1049. Epub 2018 Aug 20.

f Departments of Psychiatry, Neurology, and Psychology , University of Pittsburgh , Pittsburgh , PA , USA.

Introduction: HIV-associated neurocognitive disorders (HAND) are estimated to affect approximately 50% of infected individuals at any one time. Dispersion, a type of intraindividual variability in neurocognitive test performance, has been identified as a potential behavioral marker of HAND; however, the specificity of dispersion to HAND and how it is influenced by participant effort when taking neurocognitive tests remain unclear.

Method: Data were analyzed from 996 (474 HIV-, 522 HIV+) men enrolled in the Multicenter AIDS Cohort Study (MACS). Read More

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http://dx.doi.org/10.1080/13803395.2018.1508554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294568PMC
December 2018
15 Reads

Exaggerated reaction to novelty as a predictor of incipient cognitive decline among community-dwelling older adults.

J Clin Exp Neuropsychol 2018 Dec 16;40(10):987-999. Epub 2018 Aug 16.

a Department of Psychology , University of Utah , Salt Lake City , UT , USA.

Objective: The ability to detect covert markers of incipient cognitive decline among older adults before cognitive decline becomes overtly evident on traditional cognitive tests represents an important topic of research. Exaggerated reactions to novelty, reflected in novelty-induced increases in action planning latencies ("novelty effect"; NE) and low openness to experience (openness), have been previously associated with incipient cognitive decline among older adults who appeared cognitively normal at baseline. The purposes of the present study were to extend prior research on the utility of these markers by examining whether (a) NE and openness each predict cognitive change uniquely, and (b) whether these indices predict cognitive change above and beyond measures of memory, executive functions, processing speed/efficiency, premorbid IQ, and depressive symptoms. Read More

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http://dx.doi.org/10.1080/13803395.2018.1457627DOI Listing
December 2018
21 Reads

Greater naturally occurring expressive suppression is associated with poorer executive functioning and motor-sequence learning among older adults.

J Clin Exp Neuropsychol 2018 Aug 13:1-15. Epub 2018 Aug 13.

a Department of Psychology , University of Utah , Salt Lake City , UT , USA.

Objectives: Unusually high engagement in expressive suppression (i.e., purposeful regulation of overt affect) has been associated with poorer performance on executive functioning (EF) and motor-sequence learning tasks. Read More

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http://dx.doi.org/10.1080/13803395.2018.1502257DOI Listing
August 2018
1 Read

Parent depressive symptoms and offspring executive functioning.

J Clin Exp Neuropsychol 2018 Aug 13:1-11. Epub 2018 Aug 13.

a Department of Psychology , Idaho State University , Pocatello , ID , USA.

Introduction: Previous research has found mixed results when assessing the association between a parent's history of depressive symptoms and a child's abilities on measures of executive functioning. The purpose of this study was to replicate and expand upon these findings by evaluating the influence of a parent's depressive symptoms on a young person's executive functioning.

Method: As part of a larger study, 135 children (54. Read More

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https://www.tandfonline.com/doi/full/10.1080/13803395.2018.1
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http://dx.doi.org/10.1080/13803395.2018.1504893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474825PMC
August 2018
17 Reads

Facial expression recognition in Alzheimer's disease: A systematic review.

J Clin Exp Neuropsychol 2018 Aug 8:1-12. Epub 2018 Aug 8.

a Center for Alzheimer's Disease , Institute of Psychiatry, Federal University of Rio de Janeiro , Rio de Janeiro , Brazil.

Introduction: It is well established that behavioral variant frontotemporal dementia can impair social and emotional function. However, there is no consensus regarding how Alzheimer's disease can affect facial expression recognition. We aim to systematically review all the literature addressing this issue over the last 10 years. Read More

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http://dx.doi.org/10.1080/13803395.2018.1501001DOI Listing
August 2018
3 Reads

Motor imagery in chronic neglect: An fMRI pilot study.

J Clin Exp Neuropsychol 2019 Feb 6;41(1):58-68. Epub 2018 Aug 6.

d Department of Neurology , University of Heidelberg , Heidelberg , Germany.

Aim: Previous studies indicate the effectiveness of motor imagery training in stroke patients. To determine whether patients showing chronic visuospatial neglect symptoms may profit from motor imagery training, it is important to assess how the brain implements motor imagery when cortical systems involved in attentional control are impaired.

Method: Therefore, in this pilot study, nine chronic neglect patients with right-hemispheric stroke performed motor imagery of a finger opposition task during functional magnetic resonance imaging (fMRI). Read More

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http://dx.doi.org/10.1080/13803395.2018.1500527DOI Listing
February 2019
6 Reads

The origin of the centrality deficit in individuals with attention-deficit/hyperactivity disorder.

J Clin Exp Neuropsychol 2019 Feb 1;41(1):69-86. Epub 2018 Aug 1.

a School of Education , Bar Ilan University , Ramat-Gan , Israel.

Introduction: Studies have shown that skilled and disabled readers recall central ideas, which are important to the overall comprehension of the text, to a greater extent than peripheral, less important ideas after reading. However, readers with attention-deficit/hyperactivity disorder (ADHD) recall significantly fewer central ideas than skilled readers. The present study was designed to examine whether difficulties in identifying, attending, and/or retrieving central ideas underlie their centrality deficit. Read More

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http://dx.doi.org/10.1080/13803395.2018.1501000DOI Listing
February 2019
19 Reads

Monitoring cognition during awake brain surgery in adults: A systematic review.

Authors:
Carla Ruis

J Clin Exp Neuropsychol 2018 Dec 1;40(10):1081-1104. Epub 2018 Aug 1.

a Department of Neurology and Neurosurgery , University Medical Center Utrecht , Utrecht , The Netherlands.

Introduction: Historically, most studies about awake brain surgery have focused on language or motor functions. More recently, other cognitive functions have also been assessed. However, a clear overview of the neuropsychological tests or test paradigms that are used during such procedures is missing. Read More

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http://dx.doi.org/10.1080/13803395.2018.1469602DOI Listing
December 2018
1 Read

Comparing the effect of the subcategories of atypical antipsychotic medications on cognition in schizophrenia using a meta-analytic approach.

J Clin Exp Neuropsychol 2019 Feb 20;41(1):26-42. Epub 2018 Jul 20.

a School of Psychology and Public Health , La Trobe University , Bundoora , VIC , Australia.

Objectives: The aim of this study was to compare the two most commonly prescribed classes of atypical antipsychotic medications (i.e., -pines and -dones) with regard to their effects on cognition in patients with schizophrenia. Read More

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http://dx.doi.org/10.1080/13803395.2018.1488952DOI Listing
February 2019
1 Read

Improved conceptual generation and selection with transcranial direct current stimulation in older adults.

J Clin Exp Neuropsychol 2019 Feb 17;41(1):43-57. Epub 2018 Jul 17.

a Neuropsychology Research Unit, School of Psychology , The University of Queensland , St. Lucia, Brisbane , QLD , Australia.

Introduction: Normal aging is associated with deficits in various aspects of spoken language production, including idea generation and selection, and involves activity in frontal brain areas including left inferior frontal cortex (LIFG). These conceptual preparation processes, largely involving executive control, precede formulation and articulation stages and are critical for language production. Noninvasive brain stimulation (e. Read More

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http://dx.doi.org/10.1080/13803395.2018.1491529DOI Listing
February 2019
6 Reads

Prospective evaluation of first and last memory reports following moderate to severe traumatic brain injury.

J Clin Exp Neuropsychol 2019 Mar 9;41(2):109-117. Epub 2018 Jul 9.

a Monash Institute of Cognitive and Clinical Neurosciences, School of Psychological Sciences , Monash University , Clayton , VIC , Australia.

Prospective monitoring of posttraumatic amnesia (PTA) status is recommended following traumatic brain injury (TBI). Use of patients' subjective reports is, however, still common and necessary in some circumstances. It is therefore important to understand how patients' self-reported first memories relate to prospective measures and how reliable these reports remain over time. Read More

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http://dx.doi.org/10.1080/13803395.2018.1490392DOI Listing
March 2019
2 Reads