1,376 results match your criteria Journal of Cardiovascular Magnetic Resonance [Journal]


Maldistribution of pulmonary blood flow in patients after the Fontan operation is associated with worse exercise capacity.

J Cardiovasc Magn Reson 2018 Dec 17;20(1):85. Epub 2018 Dec 17.

Department of Cardiology, Boston Children's Hospital, Boston, MA, USA.

Background: Maldistribution of pulmonary artery blood flow (MPBF) is a potential complication in patients who have undergone single ventricle palliation culminating in the Fontan procedure. Cardiovascular magnetic resonance (CMR) is the best modality that can evaluate MPBF in this population. The purpose of this study is to identify the prevalence and associations of MPBF and to determine the impact of MPBF on exercise capacity after the Fontan operation. Read More

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http://dx.doi.org/10.1186/s12968-018-0505-4DOI Listing
December 2018

Cardiovascular magnetic resonance left ventricular strain in end-stage renal disease patients after kidney transplantation.

J Cardiovasc Magn Reson 2018 Dec 17;20(1):83. Epub 2018 Dec 17.

University of Toronto, Toronto, Canada.

Background: Cardiovascular disease is a significant cause of morbidity and mortality in patients with end-stage renal disease (ESRD) and kidney transplant (KT) patients. Compared with left ventricular (LV) ejection fraction (LVEF), LV strain has emerged as an important marker of LV function as it is less load dependent. We sought to evaluate changes in LV strain using cardiovascular magnetic resonance imaging (CMR) in ESRD patients who received KT, to determine whether KT may improve LV function. Read More

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http://dx.doi.org/10.1186/s12968-018-0504-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296102PMC
December 2018

Impaired aortic distensibility and elevated central blood pressure in Turner Syndrome: a cardiovascular magnetic resonance study.

J Cardiovasc Magn Reson 2018 Dec 13;20(1):80. Epub 2018 Dec 13.

Department of Endocrinology and Internal Medicine and Medical Research Laboratories, Aarhus University Hospital, Nørrebrogade 44, 8000, Aarhus C, Denmark.

Background: Women with Turner Syndrome have an increased risk for aortic dissection. Arterial stiffening is a risk factor for aortic dilatation and dissection. Here we investigate if arterial stiffening can be observed in Turner Syndrome patients and is an initial step in the development of aortic dilatation and subsequent dissection. Read More

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http://dx.doi.org/10.1186/s12968-018-0497-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292015PMC
December 2018

Simultaneous multi slice (SMS) balanced steady state free precession first-pass myocardial perfusion cardiovascular magnetic resonance with iterative reconstruction at 1.5 T.

J Cardiovasc Magn Reson 2018 Dec 10;20(1):84. Epub 2018 Dec 10.

School of Biomedical Engineering and Imaging Sciences, King's College London, 3rd Floor Lambeth Wing, St Thomas' Hospital, Westminster Bridge Road, London, SW1 7EH, UK.

Background: Simultaneous-Multi-Slice (SMS) perfusion imaging has the potential to acquire multiple slices, increasing myocardial coverage without sacrificing in-plane spatial resolution. To maximise signal-to-noise ratio (SNR), SMS can be combined with a balanced steady state free precession (bSSFP) readout. Furthermore, application of gradient-controlled local Larmor adjustment (GC-LOLA) can ensure robustness against off-resonance artifacts and SNR loss can be mitigated by applying iterative reconstruction with spatial and temporal regularisation. Read More

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http://dx.doi.org/10.1186/s12968-018-0502-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287353PMC
December 2018

Cardiac work is related to creatine kinase energy supply in human heart failure: a cardiovascular magnetic resonance spectroscopy study.

J Cardiovasc Magn Reson 2018 Dec 10;20(1):81. Epub 2018 Dec 10.

Division of MR Research, Department of Radiology, The Johns Hopkins University, Park Building, 600 N Wolfe St, Baltimore, MD 21287, USA.

Background: It has been hypothesized that the supply of chemical energy may be insufficient to fuel normal mechanical pump function in heart failure (HF). The creatine kinase (CK) reaction serves as the heart's primary energy reserve, and the supply of adenosine triphosphate (ATP flux) it provides is reduced in human HF. However, the relationship between the CK energy supply and the mechanical energy expended has never been quantified in the human heart. Read More

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http://dx.doi.org/10.1186/s12968-018-0491-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287363PMC
December 2018

Real-time assessment of right and left ventricular volumes and function in children using high spatiotemporal resolution spiral bSSFP with compressed sensing.

J Cardiovasc Magn Reson 2018 Dec 6;20(1):79. Epub 2018 Dec 6.

UCL Centre for Cardiovascular Imaging, Institute of Cardiovascular Science, University College London, 30 Guildford Street, London, WC1N 1EH, UK.

Background: Real-time cardiovascular magnetic resonance (CMR) assessment of ventricular volumes and function enables data acquisition during free-breathing. The requirement for high spatiotemporal resolution in children necessitates the use of highly accelerated imaging techniques.

Methods: A novel real-time balanced steady state free precession (bSSFP) spiral sequence reconstructed using Compressed Sensing (CS) was prospectively validated against the breath-hold clinical standard for assessment of ventricular volumes in 60 children with congenital heart disease. Read More

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http://dx.doi.org/10.1186/s12968-018-0500-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282387PMC
December 2018
1 Read

Diagnostic and prognostic significance of cardiovascular magnetic resonance native myocardial T1 mapping in patients with pulmonary hypertension.

J Cardiovasc Magn Reson 2018 Dec 3;20(1):78. Epub 2018 Dec 3.

POLARIS, Academic Radiology, Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK.

Background: Native T1 may be a sensitive, contrast-free, non-invasive cardiovascular magnetic resonance (CMR) marker of myocardial tissue changes in patients with pulmonary artery hypertension. However, the diagnostic and prognostic value of native T1 mapping in this patient group has not been fully explored. The aim of this work was to determine whether elevation of native T1 in myocardial tissue in pulmonary hypertension: (a) varies according to pulmonary hypertension subtype; (b) has prognostic value and (c) is associated with ventricular function and interaction. Read More

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http://dx.doi.org/10.1186/s12968-018-0501-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276188PMC
December 2018

Multidimensional fetal flow imaging with cardiovascular magnetic resonance: a feasibility study.

J Cardiovasc Magn Reson 2018 Nov 29;20(1):77. Epub 2018 Nov 29.

Medical Biophysics, University of Toronto, Toronto, ON, Canada.

Purpose: To image multidimensional flow in fetuses using golden-angle radial phase contrast cardiovascular magnetic resonance (PC-CMR) with motion correction and retrospective gating.

Methods: A novel PC-CMR method was developed using an ungated golden-angle radial acquisition with continuously incremented velocity encoding. Healthy subjects (n = 5, 27 ± 3 years, males) and pregnant females (n = 5, 34 ± 2 weeks gestation) were imaged at 3 T using the proposed sequence. Read More

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https://jcmr-online.biomedcentral.com/articles/10.1186/s1296
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http://dx.doi.org/10.1186/s12968-018-0498-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264058PMC
November 2018
5 Reads

Feasibility of 3D black-blood variable refocusing angle fast spin echo cardiovascular magnetic resonance for visualization of the whole heart and great vessels in congenital heart disease.

J Cardiovasc Magn Reson 2018 Nov 26;20(1):76. Epub 2018 Nov 26.

Departments of Pediatrics and Radiology, University of Texas Southwestern/Children's Health, Dallas, TX, USA.

Background: Volumetric black-blood cardiovascular magnetic resonance (CMR) has been hampered by long scan times and flow sensitivity. The purpose of this study was to assess the feasibility of black-blood, electrocardiogram (ECG)-triggered and respiratory-navigated 3D fast spin echo (3D FSE) for the visualization of the whole heart and great vessels.

Methods: The implemented 3D FSE technique used slice-selective excitation and non-selective refocusing pulses with variable flip angles to achieve constant echo signal for tissue with T1 (880 ms) and T2 (40 ms) similar to the vessel wall. Read More

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https://jcmr-online.biomedcentral.com/articles/10.1186/s1296
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http://dx.doi.org/10.1186/s12968-018-0508-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260764PMC
November 2018
2 Reads

Asymptomatic myocardial ischemia forecasts adverse events in cardiovascular magnetic resonance dobutamine stress testing of high-risk middle-aged and elderly individuals.

J Cardiovasc Magn Reson 2018 Nov 22;20(1):75. Epub 2018 Nov 22.

Department of Internal Medicine, Cardiovascular Medicine Section, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina, 27157-1045, USA.

Background: Current guidelines for assessing the risk of experiencing a hospitalized cardiovascular (CV) event discourage stress testing of asymptomatic individuals; however, these recommendations are based on evidence gathered primarily from those aged < 60 years, and do not address the possibility of unrecognized "silent myocardial ischemia" in middle aged and older adults.

Methods: We performed dobutamine cardiovascular magnetic resonance (CMR) stress testing in 327 consecutively recruited participants aged > 55 years without CV-related symptoms nor known coronary artery disease, but otherwise at increased risk for a future CV event due to pre-existing hypertension or diabetes mellitus for at least 5 years. After adjusting for the demographics and CV risk factors, log-rank test and Cox proportional hazards models determined the additional predictive value of the stress test results for forecasting hospitalized CV events/survival. Read More

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http://dx.doi.org/10.1186/s12968-018-0492-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249873PMC
November 2018
2 Reads

Importance of operator training and rest perfusion on the diagnostic accuracy of stress perfusion cardiovascular magnetic resonance.

J Cardiovasc Magn Reson 2018 Nov 19;20(1):74. Epub 2018 Nov 19.

School of Biomedical Engineering & Imaging Sciences, King's College London, King's Health Partners, 4th Floor Lambeth Wing, St Thomas' Hospital, London, SE1 7EH, UK.

Background: Clinical evaluation of stress perfusion cardiovascular magnetic resonance (CMR) is currently based on visual assessment and has shown high diagnostic accuracy in previous clinical trials, when performed by expert readers or core laboratories. However, these results may not be generalizable to clinical practice, particularly when less experienced readers are concerned. Other factors, such as the level of training, the extent of ischemia, and image quality could affect the diagnostic accuracy. Read More

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https://jcmr-online.biomedcentral.com/articles/10.1186/s1296
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http://dx.doi.org/10.1186/s12968-018-0493-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245890PMC
November 2018
7 Reads

Quantitative myocardial first-pass cardiovascular magnetic resonance perfusion imaging using hyperpolarized [1-C] pyruvate.

J Cardiovasc Magn Reson 2018 Nov 12;20(1):73. Epub 2018 Nov 12.

Institute for Biomedical Engineering, University and ETH Zurich, Gloriastrasse, 35 8092, Zurich, Switzerland.

Background: The feasibility of absolute myocardial blood flow quantification and suitability of hyperpolarized [1-C] pyruvate as contrast agent for first-pass cardiovascular magnetic resonance (CMR) perfusion measurements are investigated with simulations and demonstrated in vivo in a swine model.

Methods: A versatile simulation framework for hyperpolarized CMR subject to physical, physiological and technical constraints was developed and applied to investigate experimental conditions for accurate perfusion CMR with hyperpolarized [1-C] pyruvate. Absolute and semi-quantitative perfusion indices were analyzed with respect to experimental parameter variations and different signal-to-noise ratio (SNR) levels. Read More

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http://dx.doi.org/10.1186/s12968-018-0495-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231262PMC
November 2018

Incidence and predictors of left ventricular thrombus by cardiovascular magnetic resonance in acute ST-segment elevation myocardial infarction treated by primary percutaneous coronary intervention: a meta-analysis.

J Cardiovasc Magn Reson 2018 Nov 8;20(1):72. Epub 2018 Nov 8.

The Hatter Cardiovascular Institute, Institute of Cardiovascular Science, University College London, London, UK.

Introduction: The incidence of left ventricular (LV) thrombus formation in ST-segment elevation myocardial infarction (STEMI) patients in the current era of primary percutaneous coronary intervention (PCI) is not well established. We performed a meta-analysis to assess the actual incidence and predictors of LV thrombus by cardiovascular magnetic resonance (CMR) in STEMI treated by primary PCI.

Methods: We searched MEDLINE and EMBASE databases up to February 2018. Read More

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https://jcmr-online.biomedcentral.com/articles/10.1186/s1296
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http://dx.doi.org/10.1186/s12968-018-0494-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222991PMC
November 2018
5 Reads

Validation of a rapid semi-automated method to assess left atrial longitudinal phasic strains on cine cardiovascular magnetic resonance imaging.

J Cardiovasc Magn Reson 2018 Nov 5;20(1):71. Epub 2018 Nov 5.

National Heart Research Institute Singapore, National Heart Centre Singapore, 5 Hospital Drive, Singapore, 169609, Singapore.

Background: Abnormal left atrial (LA) function is a marker of cardiac dysfunction and adverse cardiovascular outcome, but is difficult to assess, and hence not, routinely quantified. We aimed to determine the feasibility and effectiveness of a fast method to measure long-axis LA strain and strain rate (SR) with standard cardiovascular magnetic resonance (CMR) compared to conventional feature tracking (FT) derived longitudinal strain.

Methods: We studied 50 normal controls, 30 patients with hypertrophic cardiomyopathy, and 100 heart failure (HF) patients, including 40 with reduced ejection fraction (HFrEF), 30 mid-range ejection fraction (HFmrEF) and 30 preserved ejection fraction (HFpEF). Read More

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https://jcmr-online.biomedcentral.com/articles/10.1186/s1296
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http://dx.doi.org/10.1186/s12968-018-0496-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219067PMC
November 2018
3 Reads

Semi-automatic detection of myocardial trabeculation using cardiovascular magnetic resonance: correlation with histology and reproducibility in a mouse model of non-compaction.

J Cardiovasc Magn Reson 2018 Oct 25;20(1):70. Epub 2018 Oct 25.

Aix-Marseille University, CNRS, CRMBM, Marseille, France.

Background: The definition of left ventricular (LV) non-compaction is controversial, and discriminating between normal and excessive LV trabeculation remains challenging. Our goal was to quantify LV trabeculation on cardiovascular magnetic resonance (CMR) images in a genetic mouse model of non-compaction using a dedicated semi-automatic software package and to compare our results to the histology used as a gold standard.

Methods: Adult mice with ventricular non-compaction were generated by conditional trabecular deletion of Nkx2-5. Read More

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http://dx.doi.org/10.1186/s12968-018-0489-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201553PMC
October 2018

Cardiovascular magnetic resonance evidence of myocardial fibrosis and its clinical significance in adolescent and adult patients with Ebstein's anomaly.

J Cardiovasc Magn Reson 2018 Sep 27;20(1):69. Epub 2018 Sep 27.

Department of Cardiology, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan Province, China.

Background: Myocardial fibrosis is a common pathophysiological process that is related to ventricular remodeling in congenital heart disease. However, the presence, characteristics, and clinical significance of myocardial fibrosis in Ebstein's anomaly have not been fully investigated. This study aimed to evaluate myocardial fibrosis using cardiovascular magnetic resonance (CMR) late gadolinium enhancement (LGE) and T1 mapping techniques, and to explore the significance of myocardial fibrosis in adolescent and adult patients with Ebstein's anomaly. Read More

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http://dx.doi.org/10.1186/s12968-018-0488-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158838PMC
September 2018
7 Reads

Cardiovascular magnetic resonance imaging in the prospective, population-based, Hamburg City Health cohort study: objectives and design.

J Cardiovasc Magn Reson 2018 Sep 24;20(1):68. Epub 2018 Sep 24.

University Heart Center Hamburg, Department of General and Interventional Cardiology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.

Background: The purpose of this work is to describe the objectives and design of cardiovascular magnetic resonance (CMR) imaging in the single center, prospective, population-based Hamburg City Health study (HCHS). The HCHS aims at improving risk stratification for coronary artery disease (CAD), atrial fibrillation (AF) and heart failure (HF).

Methods: The HCHS will finally include 45,000 inhabitants of the city of Hamburg (Germany) between 45 and 74 years who undergo an extensive cardiovascular evaluation and collection of biomaterials. Read More

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http://dx.doi.org/10.1186/s12968-018-0490-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151919PMC
September 2018
3 Reads

Society for Cardiovascular Magnetic Resonance (SCMR) expert consensus for CMR imaging endpoints in clinical research: part I - analytical validation and clinical qualification.

J Cardiovasc Magn Reson 2018 Sep 20;20(1):67. Epub 2018 Sep 20.

Institute of Experimental and Translational Cardiovascular Imaging, Goethe University Hospital Frankfurt, Frankfurt, Germany.

Cardiovascular disease remains a leading cause of morbidity and mortality globally. Changing natural history of the disease due to improved care of acute conditions and ageing population necessitates new strategies to tackle conditions which have more chronic and indolent course. These include an increased deployment of safe screening methods, life-long surveillance, and monitoring of both disease activity and tailored-treatment, by way of increasingly personalized medical care. Read More

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http://dx.doi.org/10.1186/s12968-018-0484-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147157PMC
September 2018

Effect of isolated left bundle-branch block on biventricular volumes and ejection fraction: a cardiovascular magnetic resonance assessment.

J Cardiovasc Magn Reson 2018 Sep 20;20(1):66. Epub 2018 Sep 20.

Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA, 02215, USA.

Background: Left bundle branch block (LBBB) is associated with abnormal left ventricular (LV) contraction, and is frequently associated with co-morbid cardiovascular disease, but the effect of an isolated (i.e. in the absence of cardiovascular dissease) LBBB on biventricular volumes and ejection fraction (EF) is not well characterized. Read More

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http://dx.doi.org/10.1186/s12968-018-0457-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146610PMC
September 2018

Three-dimensional free breathing whole heart cardiovascular magnetic resonance T mapping at 3 T.

J Cardiovasc Magn Reson 2018 Sep 17;20(1):64. Epub 2018 Sep 17.

Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China.

Background: This study demonstrates a three-dimensional (3D) free-breathing native myocardial T mapping sequence at 3 T.

Methods: The proposed sequence acquires three differently T-weighted volumes. The first two volumes receive a saturation pre-pulse with different recovery time. Read More

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https://jcmr-online.biomedcentral.com/articles/10.1186/s1296
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http://dx.doi.org/10.1186/s12968-018-0487-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139904PMC
September 2018
4 Reads

Automated cardiovascular magnetic resonance image analysis with fully convolutional networks.

J Cardiovasc Magn Reson 2018 Sep 14;20(1):65. Epub 2018 Sep 14.

Biomedical Image Analysis Group, Department of Computing, Imperial College London, London, UK.

Background: Cardiovascular resonance (CMR) imaging is a standard imaging modality for assessing cardiovascular diseases (CVDs), the leading cause of death globally. CMR enables accurate quantification of the cardiac chamber volume, ejection fraction and myocardial mass, providing information for diagnosis and monitoring of CVDs. However, for years, clinicians have been relying on manual approaches for CMR image analysis, which is time consuming and prone to subjective errors. Read More

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http://dx.doi.org/10.1186/s12968-018-0471-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138894PMC
September 2018
2 Reads
4.560 Impact Factor

Comparison of left ventricular strains and torsion derived from feature tracking and DENSE CMR.

J Cardiovasc Magn Reson 2018 Sep 13;20(1):63. Epub 2018 Sep 13.

Department of Biomedical Engineering, University of Kentucky, Lexington, KY, USA.

Background: Cardiovascular magnetic resonance (CMR) feature tracking is increasingly used to quantify cardiac mechanics from cine CMR imaging, although validation against reference standard techniques has been limited. Furthermore, studies have suggested that commonly-derived metrics, such as peak global strain (reported in 63% of feature tracking studies), can be quantified using contours from just two frames - end-diastole (ED) and end-systole (ES) - without requiring tracking software. We hypothesized that mechanics derived from feature tracking would not agree with those derived from a reference standard (displacement-encoding with stimulated echoes (DENSE) imaging), and that peak strain from feature tracking would agree with that derived using simple processing of only ED and ES contours. Read More

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http://dx.doi.org/10.1186/s12968-018-0485-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136226PMC
September 2018

Blood volume measurement using cardiovascular magnetic resonance and ferumoxytol: preclinical validation.

J Cardiovasc Magn Reson 2018 Sep 10;20(1):62. Epub 2018 Sep 10.

Division of Intramural Research, National Heart Lung and Blood Institute, National Institutes of Health, Building 10, Room 2C713, 10 Center Drive, Bethesda, MD, 20892, USA.

Background: The hallmark of heart failure is increased blood volume. Quantitative blood volume measures are not conveniently available and are not tested in heart failure management. We assess ferumoxytol, a marketed parenteral iron supplement having a long intravascular half-life, to measure the blood volume with cardiovascular magnetic resonance (CMR). Read More

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http://dx.doi.org/10.1186/s12968-018-0486-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131893PMC
September 2018
8 Reads

Assessment of longitudinal distribution of subclinical atherosclerosis in femoral arteries by three-dimensional cardiovascular magnetic resonance vessel wall imaging.

J Cardiovasc Magn Reson 2018 Sep 3;20(1):60. Epub 2018 Sep 3.

Center for Biomedical Imaging Research, Department of Biomedical Engineering, Tsinghua University School of Medicine, Beijing, China.

Background: Lower extremity peripheral artery disease has become a significant health burden worldwide. Since the treatment strategies can be different if atherosclerotic disease involves different femoral artery segments, it is important to assess plaque distribution among different segments of femoral arteries. We sought to investigate the longitudinal distribution of subclinical femoral artery atherosclerosis in asymptomatic elderly adults using cardiovascular magnetic resonance (CMR) vessel wall imaging. Read More

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http://dx.doi.org/10.1186/s12968-018-0482-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120082PMC
September 2018
4.560 Impact Factor

Left ventricular blood flow kinetic energy after myocardial infarction - insights from 4D flow cardiovascular magnetic resonance.

J Cardiovasc Magn Reson 2018 Aug 30;20(1):61. Epub 2018 Aug 30.

Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, Leeds, LS2 9JT, UK.

Background: Myocardial infarction (MI) leads to complex changes in left ventricular (LV) haemodynamics that are linked to clinical outcomes. We hypothesize that LV blood flow kinetic energy (KE) is altered in MI and is associated with LV function and infarct characteristics. This study aimed to investigate the intra-cavity LV blood flow KE in controls and MI patients, using cardiovascular magnetic resonance (CMR) four-dimensional (4D) flow assessment. Read More

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http://dx.doi.org/10.1186/s12968-018-0483-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117925PMC
August 2018
1 Read

Cardiovascular magnetic resonance in heart transplant patients: diagnostic value of quantitative tissue markers: T2 mapping and extracellular volume fraction, for acute rejection diagnosis.

J Cardiovasc Magn Reson 2018 Aug 27;20(1):59. Epub 2018 Aug 27.

Department of Radiology, University François Rabelais, Tours, France.

Background: The diagnosis of acute rejection in cardiac transplant recipients requires invasive technique with endomyocardial biopsy (EMB) which has risks and limitations. Cardiovascular magnetic resonance imaging (CMR) with T2 and T1 mapping is a promising technique for characterizing myocardial tissue. The purpose of the study was to evaluate T2, T1 and extracellular volume fraction (ECV) quantification as novel tissue markers to diagnose acute rejection. Read More

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https://jcmr-online.biomedcentral.com/articles/10.1186/s1296
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http://dx.doi.org/10.1186/s12968-018-0480-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114788PMC
August 2018
8 Reads

Myocardial native T2 measurement to differentiate light-chain and transthyretin cardiac amyloidosis and assess prognosis.

J Cardiovasc Magn Reson 2018 Aug 16;20(1):58. Epub 2018 Aug 16.

Radiology Department, Henri Mondor Hospital, University Paris Est Créteil, Assistance Publique-Hôpitaux de Paris, 51 av Mal de Lattre de Tassigny, 94000, Créteil, France.

Background: To assess the diagnostic and prognosis value of myocardial native T2 measurement in the distinction between Light-chain (AL) and Transthyretin (ATTR) cardiac amyloidosis (CA).

Methods: Forty-four patients with CA (24 AL; 20 ATTR) and 40 healthy subjects underwent 1.5 T cardiovascular magnetic resonance (CMR). Read More

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http://dx.doi.org/10.1186/s12968-018-0478-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097442PMC
August 2018
7 Reads

Guidelines for training in cardiovascular magnetic resonance (CMR).

J Cardiovasc Magn Reson 2018 Aug 16;20(1):57. Epub 2018 Aug 16.

Hospital of the University of Pennsylvania, Philadelphia, USA.

These "Guidelines for training in Cardiovascular Magnetic Resonance" were developed by the Certification Committee of the Society for Cardiovascular Magnetic Resonance (SCMR) and approved by the SCMR Board of Trustees. Read More

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http://dx.doi.org/10.1186/s12968-018-0481-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094559PMC

Extracellular volume fraction measurements derived from the longitudinal relaxation of blood-based synthetic hematocrit may lead to clinical errors in 3 T cardiovascular magnetic resonance.

J Cardiovasc Magn Reson 2018 Aug 9;20(1):56. Epub 2018 Aug 9.

Department of Radiology, Southwest Hospital, Third Military Medical University, Gaotanyan Street No. 30, Shapingba district, Chongqing, China.

Background: The extracellular volume (ECV), derived from cardiovascular magnetic resonance (CMR) T1 mapping, is a biomarker of the extracellular space in the myocardium. The hematocrit (HCT), measured from venipuncture, is required for ECV measurement. We test the clinic values of synthetic ECV, which is derived from the longitudinal relaxation of blood-based (T1) synthetic hematocrit in 3 T CMR. Read More

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http://dx.doi.org/10.1186/s12968-018-0475-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083590PMC
August 2018
15 Reads

Associations and prognostic significance of diffuse myocardial fibrosis by cardiovascular magnetic resonance in heart failure with preserved ejection fraction.

J Cardiovasc Magn Reson 2018 Aug 8;20(1):55. Epub 2018 Aug 8.

Division of Cardiology, Department of Cardiovascular Diseases, Cliniques Universitaires St. Luc UCL, Av Hippocrate 10/2806, B-1200, Woluwé St. Lambert, Belgium.

Background: Increased myocardial fibrosis may play a key role in heart failure with preserved ejection fraction (HFpEF) pathophysiology. The study aim was to evaluate the presence, associations, and prognostic significance of diffuse fibrosis in HFpEF patients compared to age- and sex-matched controls.

Methods: We prospectively included 118 consecutive HFpEF patients. Read More

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http://dx.doi.org/10.1186/s12968-018-0477-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081897PMC
August 2018
5 Reads

Cardiovascular magnetic resonance imaging of aorto-iliac and ilio-femoral vascular calcifications using proton density-weighted in-phase stack of stars.

J Cardiovasc Magn Reson 2018 Aug 6;20(1):51. Epub 2018 Aug 6.

Radiology, Northwestern Memorial Hospital, Chicago, IL, USA.

Background: Comparing cardiovascular magnetic resonance (CMR) angiography with computed tomography angiography (CTA), a major deficiency has been its inability to reliably image peripheral vascular calcifications that may impact the choice of interventional strategy and influence patient prognosis. Recently, MRI using a proton density-weighted, in-phase stack of stars (PDIP-SOS) technique has proved capable of detecting these calcifications. The goal of the present study was two-fold: (1) to determine whether magnetic field strength impacts the apparent size and conspicuity of ilio-femoral arterial calcifications; and (2) to determine whether the technique can be accurately applied to image aorto-iliac arterial calcifications. Read More

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http://dx.doi.org/10.1186/s12968-018-0479-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091148PMC
August 2018
1 Read

Circulating levels of P-selectin and E-selectin relate to cardiovascular magnetic resonance-derived aortic characteristics in young adults from the general population, a cross-sectional study.

J Cardiovasc Magn Reson 2018 Aug 2;20(1):54. Epub 2018 Aug 2.

Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands.

Background: Although endothelial cell adhesion molecules (CAMs) are postulated to play a key role in early atherosclerosis, studies on endothelial CAMs are mainly pertained to middle-aged populations and populations with an unfavourable cardiovascular risk burden. Therefore, this study evaluated whether circulating endothelial CAMs are related to cardiovascular magnetic resonance imaging (CMR) derived indicators of arterial wall alterations in a random sample of young adults from the general population.

Methods: This cross-sectional study is part of the general-population-based Atherosclerosis-Monitoring-and-Biomarker-measurements-In-The-YOuNg (AMBITYON) cohort study. Read More

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http://dx.doi.org/10.1186/s12968-018-0473-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090925PMC

Myocardial tissue characterization and strain analysis in healthy pregnant women using cardiovascular magnetic resonance native T1 mapping and feature tracking technique.

J Cardiovasc Magn Reson 2018 Aug 2;20(1):52. Epub 2018 Aug 2.

Department of Obstetrics and Gynecology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.

Background: Peripartum cardiomyopathy is a life-threatening condition that occurs during the peripartum period in previously healthy women. Cardiovascular magnetic resonance (CMR) T1 mapping permits sensitive detection of tissue edema and fibrosis, and it may be useful in identifying altered myocardial tissue characteristics in peripartum cardiomyopathy. However, left ventricular (LV) volumes and mass increase considerably even in normal pregnancy, and it is not known whether altered tissue characteristics can be found in normal pregnancy. Read More

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http://dx.doi.org/10.1186/s12968-018-0476-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090929PMC
August 2018
1 Read
4.560 Impact Factor

Diabetes mellitus and insulin resistance associate with left ventricular shape and torsion by cardiovascular magnetic resonance imaging in asymptomatic individuals from the multi-ethnic study of atherosclerosis.

J Cardiovasc Magn Reson 2018 Jul 30;20(1):53. Epub 2018 Jul 30.

Department of Cardiology, Johns Hopkins University, Baltimore, MD, USA.

Background: Although diabetes mellitus (DM) and insulin resistance associate with adverse cardiac events, the associations of left ventricular (LV) remodeling and function with compromised glucose metabolism have not been fully evaluated in a general population. We used cardiovascular magnetic resonance (CMR) to evaluate how CMR indices are associated with DM or insulin resistance among participants before developing cardiac events.

Methods: We studied 1476 participants who were free of clinical cardiovascular disease and who underwent tagged CMR in the Multi-Ethnic Study of Atherosclerosis (MESA). Read More

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http://dx.doi.org/10.1186/s12968-018-0472-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069876PMC
July 2018
7 Reads

Relationship between CMR-derived parameters of ischemia/reperfusion injury and the timing of CMR after reperfused ST-segment elevation myocardial infarction.

J Cardiovasc Magn Reson 2018 Jul 23;20(1):50. Epub 2018 Jul 23.

Centre of Cardiac Magnetic Resonance, University Hospital Lausanne-CHUV, Lausanne, Switzerland.

Background: To investigate the influence of cardiovascular magnetic resonance (CMR) timing after reperfusion on CMR-derived parameters of ischemia/reperfusion (I/R) injury in patients with ST-segment elevation myocardial infarction (STEMI).

Methods: The study included 163 reperfused STEMI patients undergoing CMR during the index hospitalization. Patients were divided according to the time between revascularization and CMR (T: Tertile-1 ≤ 43; 43 < Tertile-2 ≤ 93; Tertile-3 > 93 h). Read More

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http://dx.doi.org/10.1186/s12968-018-0474-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055335PMC
July 2018
5 Reads

A multi-band double-inversion radial fast spin-echo technique for T2 cardiovascular magnetic resonance mapping of the heart.

J Cardiovasc Magn Reson 2018 Jul 19;20(1):49. Epub 2018 Jul 19.

Department of Medical Imaging, University of Arizona, Tucson, AZ, USA.

Background: Double inversion recovery (DIR) fast spin-echo (FSE) cardiovascular magnetic resonance (CMR) sequences are used clinically for black-blood T2-weighted imaging. However, these sequences suffer from slice inefficiency due to the non-selective inversion pulses. We propose a multi-band (MB) encoded DIR radial FSE (MB-DIR-RADFSE) technique to simultaneously excite two slices. Read More

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http://dx.doi.org/10.1186/s12968-018-0470-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052643PMC

Fully automated, inline quantification of myocardial blood flow with cardiovascular magnetic resonance: repeatability of measurements in healthy subjects.

J Cardiovasc Magn Reson 2018 Jul 9;20(1):48. Epub 2018 Jul 9.

Multidisciplinary Cardiovascular Research Centre (MCRC) & Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Clarendon Way, Leeds, LS2 9JT, UK.

Background: Non-invasive assessment of myocardial ischaemia is a cornerstone of the diagnosis of coronary artery disease. Measurement of myocardial blood flow (MBF) using positron emission tomography (PET) is the current reference standard for non-invasive quantification of myocardial ischaemia. Dynamic myocardial perfusion cardiovascular magnetic resonance (CMR) offers an alternative to PET and a recently developed method with automated inline perfusion mapping has shown good correlation of MBF values between CMR and PET. Read More

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http://dx.doi.org/10.1186/s12968-018-0462-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036695PMC
July 2018
7 Reads

Artefacts in 1.5 Tesla and 3 Tesla cardiovascular magnetic resonance imaging in patients with leadless cardiac pacemakers.

J Cardiovasc Magn Reson 2018 Jul 5;20(1):47. Epub 2018 Jul 5.

Department of Cardiology, Kepler University Hospital Linz, Med Campus III, Krankenhausstraße 9, 4021, Linz, Austria.

Background: There are limited data on patients with leadless cardiac pacemakers (LCP) undergoing magnetic resonance imaging. The aim of this prospective, single-center, observational study was to evaluate artefacts on cardiovascular magnetic resonance (CMR) images in patients with LCP.

Methods: Fifteen patients with Micra™ LCP, implanted at least 6 weeks prior to CMR scan, were enrolled and underwent either 1. Read More

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http://dx.doi.org/10.1186/s12968-018-0469-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033226PMC

Non-contrast assessment of microvascular integrity using arterial spin labeled cardiovascular magnetic resonance in a porcine model of acute myocardial infarction.

J Cardiovasc Magn Reson 2018 Jul 2;20(1):45. Epub 2018 Jul 2.

Ming Hsieh Department of Electrical Engineering, University of Southern California, Los Angeles, CA, USA.

Background: Following acute myocardial infarction (AMI), microvascular integrity and function may be compromised as a result of microvascular obstruction (MVO) and vasodilator dysfunction. It has been observed that both infarcted and remote myocardial territories may exhibit impaired myocardial blood flow (MBF) patterns associated with an abnormal vasodilator response. Arterial spin labeled (ASL) CMR is a novel non-contrast technique that can quantitatively measure MBF. Read More

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http://dx.doi.org/10.1186/s12968-018-0468-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027570PMC
July 2018
5 Reads
4.560 Impact Factor

Importance of standardizing timing of hematocrit measurement when using cardiovascular magnetic resonance to calculate myocardial extracellular volume (ECV) based on pre- and post-contrast T1 mapping.

J Cardiovasc Magn Reson 2018 Jun 28;20(1):46. Epub 2018 Jun 28.

Department of Clinical Physiology, Clinical Sciences, Lund University and Lund University Hospital, Getingevägen 3, 221 85, Lund, Sweden.

Background: Cardiovascular magnetic resonance (CMR) can be used to calculate myocardial extracellular volume fraction (ECV) by relating the longitudinal relaxation rate in blood and myocardium before and after contrast-injection to hematocrit (Hct) in blood. Hematocrit is known to vary with body posture, which could affect the calculations of ECV. The aim of this study was to test the hypothesis that there is a significant increase in calculated ECV values if the Hct is sampled after the CMR examination in supine position compared to when the patient arrives at the MR department. Read More

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http://dx.doi.org/10.1186/s12968-018-0464-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022290PMC
June 2018
3 Reads

Two-center clinical validation and quantitative assessment of respiratory triggered retrospectively cardiac gated balanced-SSFP cine cardiovascular magnetic resonance imaging in adults.

J Cardiovasc Magn Reson 2018 Jun 28;20(1):44. Epub 2018 Jun 28.

Department of Radiology, Baylor St. Luke's Medical Center, Houston, TX, USA.

Background: Breath-hold (BH) requirement remains the limiting factor on the spatio-temporal resolution and coverage of the cine balanced steady-state free precession (bSSFP) cardiovascular magnetic resonance (CMR) imaging. In this prospective two-center clinical trial, we validated the performance of a respiratory triggered (RT) bSSFP cine sequence for evaluation of biventricular function.

Methods: Our study included 23 asymptomatic healthy subjects and 60 consecutive patients from Institute A (n = 39) and Institute B (n = 21) referred for a clinically indicated CMR study. Read More

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http://dx.doi.org/10.1186/s12968-018-0467-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022503PMC
June 2018
1 Read

Cardiovascular magnetic resonance black-blood thrombus imaging for the diagnosis of acute deep vein thrombosis at 1.5 Tesla.

J Cardiovasc Magn Reson 2018 Jun 25;20(1):42. Epub 2018 Jun 25.

Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA.

Background: The aim was to investigate the feasibility of a cardiovascular magnetic resonance (CMR) black-blood thrombus imaging (BBTI) technique, based on delay alternating with nutation for tailored excitation black-blood preparation and a variable flip angle turbo-spin-echo readout, for the diagnosis of acute deep vein thrombosis (DVT) at 1.5 T.

Methods: BBTI was conducted in 15 healthy subjects and 30 acute DVT patients. Read More

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http://dx.doi.org/10.1186/s12968-018-0459-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016134PMC
June 2018
6 Reads
4.560 Impact Factor

Right heart catheterization using metallic guidewires and low SAR cardiovascular magnetic resonance fluoroscopy at 1.5 Tesla: first in human experience.

J Cardiovasc Magn Reson 2018 Jun 21;20(1):41. Epub 2018 Jun 21.

Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Building 10, Room 2C713, Bethesda, MD, 20892-1538, USA.

Background: Cardiovascular magnetic resonance (CMR) fluoroscopy allows for simultaneous measurement of cardiac function, flow and chamber pressure during diagnostic heart catheterization. To date, commercial metallic guidewires were considered contraindicated during CMR fluoroscopy due to concerns over radiofrequency (RF)-induced heating. The inability to use metallic guidewires hampers catheter navigation in patients with challenging anatomy. Read More

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http://dx.doi.org/10.1186/s12968-018-0458-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011242PMC
June 2018
2 Reads

Determination of aortic stiffness using 4D flow cardiovascular magnetic resonance - a population-based study.

J Cardiovasc Magn Reson 2018 Jun 21;20(1):43. Epub 2018 Jun 21.

Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.

Background: Increased aortic stiffness is an independent predictor of cardiovascular disease. Optimal measurement is highly beneficial for the detection of atherosclerosis and the management of patients at risk. Thus, it was our purpose to selectively measure aortic stiffness using a novel imaging method and to provide reference values from a population-based study. Read More

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http://dx.doi.org/10.1186/s12968-018-0461-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011486PMC
June 2018
1 Read

Cardiovascular magnetic resonance assessment of acute cardiovascular effects of voluntary apnoea in elite divers.

J Cardiovasc Magn Reson 2018 Jun 18;20(1):40. Epub 2018 Jun 18.

Department of Radiology, University Hospital of Bonn, Bonn, Germany.

Background: Prolonged breath holding results in hypoxemia and hypercapnia. Compensatory mechanisms help maintain adequate oxygen supply to hypoxia sensitive organs, but burden the cardiovascular system. The aim was to investigate human compensatory mechanisms and their effects on the cardiovascular system with regard to cardiac function and morphology, blood flow redistribution, serum biomarkers of the adrenergic system and myocardial injury markers following prolonged apnoea. Read More

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http://dx.doi.org/10.1186/s12968-018-0455-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004697PMC

Impact of surgical pulmonary valve replacement on ventricular strain and synchrony in patients with repaired tetralogy of Fallot: a cardiovascular magnetic resonance feature tracking study.

J Cardiovasc Magn Reson 2018 Jun 18;20(1):37. Epub 2018 Jun 18.

Department of Cardiology, Boston Children's Hospital, Boston, USA.

Background: In patients with repaired tetralogy of Fallot (TOF), a better understanding of the impact of surgical pulmonary valve replacement (PVR) on ventricular mechanics may lead to improved indications and outcomes. Therefore, we used cardiovascular magnetic resonance (CMR) feature tracking analysis to quantify ventricular strain and synchrony in repaired TOF patients before and after PVR.

Methods: Thirty-six repaired TOF patients (median age 22. Read More

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http://dx.doi.org/10.1186/s12968-018-0460-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004693PMC

Prognostic value of myocardial strain and late gadolinium enhancement on cardiovascular magnetic resonance imaging in patients with idiopathic dilated cardiomyopathy with moderate to severely reduced ejection fraction.

J Cardiovasc Magn Reson 2018 Jun 14;20(1):36. Epub 2018 Jun 14.

Department of Internal Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.

Background: It has been reported that left ventricular (LV) myocardial strain and late gadolinium enhancement (LGE) on cardiovascular magnetic resonance (CMR) imaging have prognostic value in patients with heart failure (HF). However, previous studies included patients with various systolic functions. This study aimed to investigate the prognostic value of LV myocardial strain and LGE on CMR imaging in patients with idiopathic dilated cardiomyopathy (DCM) with reduced ejection fraction (EF < 40%). Read More

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http://dx.doi.org/10.1186/s12968-018-0466-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001169PMC
June 2018
2 Reads

3D whole-brain vessel wall cardiovascular magnetic resonance imaging: a study on the reliability in the quantification of intracranial vessel dimensions.

J Cardiovasc Magn Reson 2018 Jun 14;20(1):39. Epub 2018 Jun 14.

Biomedical Imaging Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, 8700 Beverly Blvd., PACT 400, Los Angeles, CA, 90048, USA.

Background: One of the potentially important applications of three-dimensional (3D) intracranial vessel wall (IVW) cardiovascular magnetic resonance (CMR) is to monitor disease progression and regression via quantitative measurement of IVW morphology during medical management or drug development. However, a prerequisite for this application is to validate that IVW morphologic measurements based on the modality are reliable. In this study we performed comprehensive reliability analysis for the recently proposed whole-brain IVW CMR technique. Read More

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http://dx.doi.org/10.1186/s12968-018-0453-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000985PMC
June 2018
8 Reads
4.560 Impact Factor

Age-related changes of right atrial morphology and inflow pattern assessed using 4D flow cardiovascular magnetic resonance: results of a population-based study.

J Cardiovasc Magn Reson 2018 Jun 14;20(1):38. Epub 2018 Jun 14.

Department of Neurology and Neuroscience, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.

Background: To assess age-related changes of blood flow and geometry of the caval veins and right atrium (RA) using 4D flow cardiovascular magnetic resonance (CMR) data obtained in a population-based study.

Methods: An age-stratified sample (n = 126) of the population of the city of Freiburg, Germany, underwent transthoracic echocardiography and electrocardiogram-triggered and navigator-gated 4D flow CMR at 3 Tesla covering the caval veins and right heart. Study participants were divided into three age groups (1:20-39; 2:40-59; and 3:60-80 years of age). Read More

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http://dx.doi.org/10.1186/s12968-018-0456-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001162PMC
June 2018
2 Reads

Quantitative assessment of symptomatic intracranial atherosclerosis and lenticulostriate arteries in recent stroke patients using whole-brain high-resolution cardiovascular magnetic resonance imaging.

J Cardiovasc Magn Reson 2018 Jun 7;20(1):35. Epub 2018 Jun 7.

Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China.

Background: It has been shown that intracranial atherosclerotic stenosis (ICAS) has heterogeneous features in terms of plaque instability and vascular remodeling. Therefore, quantitative information on the changes of intracranial atherosclerosis and lenticulostriate arteries (LSAs) may potentially improve understanding of the pathophysiological mechanisms underlying stroke and may guide the treatment and work-up strategies. Our present study aimed to use a novel whole-brain high-resolution cardiovascular magnetic resonance imaging (WB-HRCMR) to assess both ICAS plaques and LSAs in recent stroke patients. Read More

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http://dx.doi.org/10.1186/s12968-018-0465-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992765PMC
June 2018
4 Reads
4.560 Impact Factor