3,741 results match your criteria Journal of Asthma[Journal]


Usefulness of mannitol challenge testing for diagnosing asthma in everyday clinical practice.

J Asthma 2019 Apr 16:1-7. Epub 2019 Apr 16.

a Respiratory Research Unit, Department of Respiratory Medicine , Hvidovre Hospital , Hvidovre , Denmark.

Background: The mannitol test is widely used for assessment of airway responsiveness in patients with possible asthma, but our knowledge of the value in everyday clinical practice is limited.

Objective: To investigate the diagnostic value of the mannitol test in a clinical setting.

Methods: All patients having a mannitol challenge test as part of their diagnostic work-up for asthma at the respiratory outpatient clinic, Hvidovre Hospital, over a 5-year period were included in the present analysis. Read More

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https://www.tandfonline.com/doi/full/10.1080/02770903.2019.1
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http://dx.doi.org/10.1080/02770903.2019.1600144DOI Listing
April 2019
1 Read

Asthma control test reflects not only lung function but also airway inflammation in children with stable asthma.

J Asthma 2019 Apr 10:1-6. Epub 2019 Apr 10.

a Department of Pediatrics, School of Medicine , The Catholic University of Korea , Bucheon St. Mary's Hospital , Bucheon , Korea.

Objective: Various numerical asthma control tools have been developed to distinguish different levels of symptom control. We aimed to examine whether the asthma control test (ACT) is reflective of objective findings such as lung function, fractional exhaled nitric oxide (FeNO) and laboratory data in patients with stable asthma.

Methods: We included patients who were enrolled in the Korean Childhood Asthma Study. Read More

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http://dx.doi.org/10.1080/02770903.2019.1599386DOI Listing
April 2019
1 Read
1.828 Impact Factor

US racial/ethnic disparities in childhood asthma emergent health care use: National Health Interview Survey, 2013-2015.

J Asthma 2019 Apr 8:1-11. Epub 2019 Apr 8.

a University of Michigan School of Public Health , Ann Arbor , MI , USA.

Objective: Racial/ethnic disparities in Emergency Department (ED) visits due to childhood asthma are well documented. We assessed disparities among multiple racial/ethnic groups and examined the effects of asthma management in emergent health care use among children in the United States.

Methods: Data come from the sample child component of the 2013-2015 National Health Interview Survey (NHIS) (ages 2-17). Read More

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http://dx.doi.org/10.1080/02770903.2019.1590588DOI Listing

Preschoolers with recurrent wheezing have a high prevalence of sleep disordered breathing.

J Asthma 2019 Apr 5:1-9. Epub 2019 Apr 5.

a Department of Pediatric Pulmonology and Cardiology, Division of Pediatrics, School of Medicine , Pontificia Universidad Católica de Chile , Santiago , Chile.

Objective: Sleep-disordered breathing (SDB) is highly prevalent in school children with poorly-controlled asthma. However, this association has not been assessed in preschoolers with recurrent wheeze, nor in those at risk for asthma. We hypothesized that preschoolers with asthma risk (positive asthma predictive index [API]) have a higher prevalence of SDB and higher inflammatory biomarkers (blood-hsCRP and urinary-LTE4) levels than those with negative API. Read More

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https://www.tandfonline.com/doi/full/10.1080/02770903.2019.1
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http://dx.doi.org/10.1080/02770903.2019.1599385DOI Listing
April 2019
1 Read

Evaluation of the efficacy of isopathic immunotherapy in the treatment of allergic asthma in BALB/C mice.

J Asthma 2019 Apr 3:1-10. Epub 2019 Apr 3.

a Cellular and Molecular Research Center, Cellular and Molecular Medicine Institute, Urmia University of Medical Sciences , Urmia , Iran.

Introduction: Homeopathy is a therapeutic method based on the fundamental principle of "like cures like." Homeopathic remedies are extremely dilute but involve vigorous shaking at each dilution. Isopathy is one approach of homeopathy, in which the causative agents or products of a disease are used to treat the same disease. Read More

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http://dx.doi.org/10.1080/02770903.2019.1599384DOI Listing

Serological analysis of sensitization in allergic bronchopulmonary aspergillosis: a study on allergen components and interspecies relationships.

J Asthma 2019 Apr 4:1-8. Epub 2019 Apr 4.

a Department of Respiratory Medicine II , Fujita Health University School of Medicine , Nagoya , Aichi , Japan.

Background: Serological testing for immunoglobulin (Ig) E or IgG is useful for diagnosing allergic bronchopulmonary aspergillosis (ABPA), as it detects type I and III allergic reactions to Aspergillus species. However, few reports have investigated the allergen component and cross-reactivity among Aspergillus species. We aimed to measure and analyze the levels of IgGs specific to each Aspergillus species and investigate the prevalence of IgEs specific to each allergen component of A. Read More

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http://dx.doi.org/10.1080/02770903.2019.1599387DOI Listing
April 2019
1 Read

Reference range number line format preferred by adults for display of asthma control status.

J Asthma 2019 Apr 3:1-7. Epub 2019 Apr 3.

a Columbia University School of Nursing , New York , NY , USA.

Objective: Optimal asthma self-management requires an accurate understanding of one's asthma control status. Tailored infographics are a promising way of conveying status information but little is known about which formats are effective at supporting comprehension while also being appealing to adults with asthma.

Methods: In this focus group study, we compared two formats to display Asthma Control Questionnaire (ACQ) scores: a stoplight graphic and a reference range number line (RRNL). Read More

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http://dx.doi.org/10.1080/02770903.2019.1590597DOI Listing

The association between 1,3-dichloropropene and asthma emergency department visits in California, USA from 2005 to 2011: a bidirectional-symmetric case crossover study.

J Asthma 2019 Apr 2:1-9. Epub 2019 Apr 2.

a Health Sciences Research Institute, University of California , Merced , California , USA.

Objective: The ever-increasing rate of pesticide use in California farmlands is of great concern due to its potential toxicity on human health. In this study, the association between short term exposure to 1,3-dichloropropene (1,3-D) and asthma emergency department (ED) visits in central and southern California from 2005 to 2011 is investigated.

Methods: 3878 ED visits were identified from 2005 to 2011 (1064 days). Read More

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http://dx.doi.org/10.1080/02770903.2019.1590596DOI Listing
April 2019
1.828 Impact Factor

Azithromycin treatment in children hospitalized with asthma: a retrospective cohort study.

J Asthma 2019 Apr 1:1-7. Epub 2019 Apr 1.

c Department of Pediatrics , Einstein Medical Center , Philadelphia , PA , USA.

Objective: Azithromycin has anti-inflammatory properties in the lungs and decreases the duration of asthma-like episodes in children. We sought to evaluate length of stay (LOS) and readmission rates of children receiving azithromycin therapy during hospitalization for acute asthma exacerbations.

Methods: This was a retrospective cohort study at an urban, quaternary-care children's hospital including patients under 18 years old hospitalized for asthma, without concurrent infection, from 2002 to 2011. Read More

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https://www.tandfonline.com/doi/full/10.1080/02770903.2019.1
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http://dx.doi.org/10.1080/02770903.2019.1590590DOI Listing
April 2019
7 Reads

Barriers to daily life physical activities for Brazilian children with asthma: a cross-sectional study.

J Asthma 2019 Mar 28:1-9. Epub 2019 Mar 28.

a Department of Physical Therapy, School of Medicine , University of São Paulo , São Paulo , Brazil.

Background Objective: To identify barriers to daily life physical activities (DLPA) and to evaluate physical activity levels for children with asthma and without asthma.

Method: This is a cross-sectional study that enrolled 130 children with asthma and 54 non-asthma, from 7 to 12 years old. All of the children in both groups used an accelerometer for 6 consecutive days to assess DLPA and completed a questionnaire to evaluate barriers to physical activity. Read More

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http://dx.doi.org/10.1080/02770903.2019.1594249DOI Listing
March 2019
1 Read

Validation of Strasbourg environmental exposure chamber (EEC) ALYATEC in mite allergic subjects with asthma.

J Asthma 2019 Mar 28:1-9. Epub 2019 Mar 28.

a Chest Diseases Department , Strasbourg University Hospital , Strasbourg , France.

Objective: Environmental Exposure Chamber (EEC) should have standardized and controlled allergenic and non-allergenic exposures to perform reproducible clinical studies. The aim was to demonstrate that mite exposure in the Alyatec EEC could induce early (EAR) and/or late asthmatic reactions (LAR) in at least 60% of subjects allergic to mite.

Methods: The EEC has a volume of 147-m with 20 seats. Read More

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http://dx.doi.org/10.1080/02770903.2018.1563902DOI Listing
March 2019
2 Reads

Inhalation technique and asthma outcomes with different corticosteroid-containing inhaler devices.

J Asthma 2019 Mar 27:1-9. Epub 2019 Mar 27.

a University of Ljubljana, Faculty of Pharmacy, Chair of Social Pharmacy , Ljubljana , Slovenia.

Objective: Inhaler devices must be used correctly to ensure the effectiveness of the asthma treatment. This study evaluated inhalation technique across different types of corticosteroid-containing inhaler devices as well as health outcomes in patients with asthma.

Methods: In a cross-sectional study, we evaluated inhaler technique by observing patients' handling of the inhaler devices and using checklists for four inhaler types, namely Diskus (n = 52), pressure metered dose inhalers (pMDIs; n = 41), Turbuhaler (n = 36) and Twisthaler (n = 16). Read More

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http://dx.doi.org/10.1080/02770903.2019.1591442DOI Listing

Linking endotypes to omics profiles in difficult-to-control asthma using the diagnostic Chinese medicine syndrome differentiation algorithm.

J Asthma 2019 Mar 27:1-11. Epub 2019 Mar 27.

c Guang'anmen Hospital, China Academy of Chinese Medical Sciences , Beijing , China.

Objective: Patients with difficult-to-control asthma have difficulty breathing almost all of the time, even leading to life-threatening asthma attacks. However, only few diagnostic markers for this disease have been identified. We aimed to take advantage of unique Chinese medicine theories for phenotypic classification and to explore molecular signatures in difficult-to-control asthma. Read More

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http://dx.doi.org/10.1080/02770903.2019.1590589DOI Listing
March 2019
1 Read

Key factors associated with uncontrolled asthma - the Asthma Control in Latin America Study.

J Asthma 2019 Mar 27:1-10. Epub 2019 Mar 27.

m GSK , Rio de Janeiro , Brazil.

Objective: This study aimed to estimate asthma control at specialist treatment centers in four Latin American countries and assess factors influencing poor asthma control.

Methods: Patients aged ≥12 years with an asthma diagnosis and asthma medication prescription, followed at outpatient specialist centers in Argentina, Chile, Colombia, and Mexico, were included. The study received all applicable ethical approvals. Read More

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http://dx.doi.org/10.1080/02770903.2018.1553050DOI Listing
March 2019
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Weight status and nonadherence to asthma maintenance therapy among children enrolled in a public drug insurance plan.

J Asthma 2019 Mar 26:1-11. Epub 2019 Mar 26.

b Centre de recherche du CHU Sainte-Justine , Montréal , Québec , Canada.

Objective: The pediatric obese-asthma phenotype is associated with poor control, perhaps because of medication nonadherence. This study aimed to assess whether weight status is associated with nonadherence in children prescribed new asthma maintenance therapies.

Methods: A historical cohort was constructed from a clinical database linking individual patient and prescription data to Quebec's prescription claims registry. Read More

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http://dx.doi.org/10.1080/02770903.2019.1590593DOI Listing
March 2019
1 Read

Correction.

Authors:

J Asthma 2019 Mar 26. Epub 2019 Mar 26.

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http://dx.doi.org/10.1080/02770903.2019.1594011DOI Listing
March 2019
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The effects of diet-induced weight loss on asthma control and quality of life in obese adults with asthma: a randomized controlled trial.

J Asthma 2019 Mar 23:1-9. Epub 2019 Mar 23.

b Department of Immunology and Allergy , Ankara University Medical Faculty , Ankara , Turkey.

Objective: While the effects of obesity on asthma are yet to be fully clarified, increased fat tissue is known to increase the severity of asthma and to impair asthma control. This study evaluated the effects of diet-induced weight loss on the characteristics of asthma in obese adults with asthma.

Methods: A total of 55 obese individuals (BMI ≥ 30. Read More

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http://dx.doi.org/10.1080/02770903.2019.1590594DOI Listing
March 2019
1 Read

Onset of respiratory symptoms among Chinese students: associations with dampness and redecoration, PM, NO, SO and inadequate ventilation in the school.

J Asthma 2019 Mar 23:1-10. Epub 2019 Mar 23.

a Institute of Environmental Science, Shanxi University , Taiyuan , Shanxi , China.

Objective: To study onset of respiratory symptoms among students in China in relation to the school and the home environment.

Methods: A two-year prospective cohort study among 1325 students in eight schools. Air pollution was measured at baseline in the schools. Read More

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http://dx.doi.org/10.1080/02770903.2019.1590591DOI Listing
March 2019
1 Read

Treat to target approach for asthma.

Authors:
Luis J Nannini

J Asthma 2019 Mar 23:1-4. Epub 2019 Mar 23.

a Hospital "E Perón" de Granadero Baigorria, Facultad de Ciencias Médicas , Universidad Nacional de Rosario , Rosario , Argentina.

Recognition that about half of asthma deaths might be preventable if recommended guidelines are followed suggests that better implementation of established management strategies is needed. However, to achieve a further substantive reduction in asthma mortality, novel strategies will also be required. It is well established that asthma is a disease of chronic inflammation, with episodes of worsening inflammation associated with increased symptoms and/or exacerbations; however, current guidelines paradoxically recommend that initial treatment is only symptomatic, rather than directed at the underlying inflammatory mechanism. Read More

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http://dx.doi.org/10.1080/02770903.2019.1591443DOI Listing
March 2019
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The cross-cultural validation of the English version of RhinAsthma patient's perspective (RAPP).

J Asthma 2019 Mar 25:1-7. Epub 2019 Mar 25.

e Department of Internal Medicine , IRCCS San Martino di Genova University Hospital , Genoa , Italy.

Objective: No validated instrument is currently available in English for use in daily practice to assess Health Related Quality of Life (HRQoL) in asthma and comorbid allergic rhinitis (AR). The aim of this study was to validate and assess the psychometric characteristics of an English language version of RhinAsthma Patient Perspective (RAPP).

Methods: The study was performed in the Philippines. Read More

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http://dx.doi.org/10.1080/02770903.2019.1590595DOI Listing
March 2019
1 Read

Family medicine physician teachers and residents' intentions to prescribe and interpret spirometry: a descriptive cross-sectional study.

J Asthma 2019 Mar 23:1-11. Epub 2019 Mar 23.

a Knowledge Translation, Education and Prevention Chair in Respiratory and Cardiovascular Health , Laval University , Quebec City , QC , Canada.

Background: Spirometry is the best test to demonstrate airway obstruction, but remains underused in primary care.

Objectives: We assessed, among family medicine physician teachers and residents, their intention to prescribe spirometry in patients suspected of chronic obstructive pulmonary disease and their intention to interpret the results. This evaluation is based on the theoretical framework proposed by Godin et al. Read More

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http://dx.doi.org/10.1080/02770903.2018.1553052DOI Listing
March 2019
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Omalizumab may decrease the thickness of the reticular basement membrane and fibronectin deposit in the bronchial mucosa of severe allergic asthmatics.

J Asthma 2019 Mar 23:1-10. Epub 2019 Mar 23.

a Department of Pulmonology , University Hospital , Krakow , Poland.

Introduction: Immunoglobulin E is an important modulator of the inflammatory reaction in allergic asthma. It also contributes to airway remodeling in the course of the disease. The authors evaluated airway structural changes in severe allergic asthma during the omalizumab therapy. Read More

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http://dx.doi.org/10.1080/02770903.2019.1585872DOI Listing

Effectiveness of an educational program for children and their families on asthma control treatment adherence.

J Asthma 2019 Mar 23:1-7. Epub 2019 Mar 23.

b Respiratory and Allergy Unit, 3rd Pediatric Department of National and Kapodistrian University of Athens , University General Hospital "Attikon" , Athens , Greece.

Objective: Τo investigate the effect of an asthma care educational program for children and adolescents with asthma, on adherence to asthma control treatment and on clinical indices.

Methods: Individuals newly diagnosed with asthma, aged 4-16 years, randomized to the intervention and control group. The participants were monitored for 6 weeks. Read More

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http://dx.doi.org/10.1080/02770903.2019.1585873DOI Listing

Processing small sputum samples: a method validation study.

J Asthma 2019 Mar 23:1-4. Epub 2019 Mar 23.

a College of Life Sciences, Department of Infection, Immunity and Inflammation , University of Leicester , Leicester , UK.

Background: Eosinophilia is frequently a feature of asthma. Sputum analysis can help with the diagnosis and phenotyping of asthma. The current gold standard method is unsuitable for samples <100 mg. Read More

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http://dx.doi.org/10.1080/02770903.2018.1553054DOI Listing

Status asthmaticus requiring extracorporeal membrane oxygenation associated with rhinovirus infection.

J Asthma 2019 Mar 18:1-4. Epub 2019 Mar 18.

a Division of Pulmonology , Nemours/Alfred I. duPont Hospital for Children , Wilmington , DE , USA.

Objective: Evolving research links human rhinovirus (HRV) with status asthmaticus (SA) as well as severe respiratory illness in patients with atopy and asthma. This case series reviews five episodes of HRV-associated SA that required extracorporeal membrane oxygenation (ECMO).

Methods: Charts of four patients, five total episodes of ECMO, with SA secondary to HRV were reviewed in this IRB-approved case series. Read More

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http://dx.doi.org/10.1080/02770903.2019.1565826DOI Listing
March 2019
1 Read

Altered mast cell activity in response to rhinovirus infection provides novel insight into asthma.

J Asthma 2019 Mar 18:1-9. Epub 2019 Mar 18.

a Department of Respiratory Medicine , The First Affiliated Hospital of Jinzhou Medical University , Jinzhou , China.

Objective: Human rhinoviruses (RVs) are a type of common respiratory virus capable of inducing an asthma attack. Although mast cells are important effector cells involved in allergic disease, little is known about the direct effects of an RV infection on mast cells. The aim of this study is to investigate mast cell behavior in response to RV infection and gain insight into the effects of RVs on mast cells. Read More

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http://dx.doi.org/10.1080/02770903.2019.1585870DOI Listing
March 2019
1 Read

Longitudinal trends in asthma emergency department visits, pollutant and pollen levels, and weather variables in the Bronx from 2001-2008.

J Asthma 2019 Mar 8:1-8. Epub 2019 Mar 8.

a Division of Allergy/Immunology , Montefiore Medical Center, Albert Einstein College of Medicine , Bronx , NY , USA.

Objective: To evaluate how asthma-related emergency department visits (AREDV), air pollutant levels, pollen counts, and weather variables changed from 2001 to 2008 in the Bronx, NY.

Methods: 42,065 daily AREDV values (1 January 2001 to 31 December 2008) were collected using our institution's Clinical Looking Glass software. Daily values of sulfur dioxide (SO), carbon monoxide (CO), ozone (O), nitrogen dioxide (NO), temperature, and humidity were obtained from the National Climatic Data Center's Bronx station. Read More

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https://www.tandfonline.com/doi/full/10.1080/02770903.2019.1
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http://dx.doi.org/10.1080/02770903.2019.1585871DOI Listing
March 2019
12 Reads

The prevalence and disease burden of severe eosinophilic asthma in Japan.

J Asthma 2019 Mar 1:1-12. Epub 2019 Mar 1.

a Department of Respiratory Medicine , Graduate School of Medicine, Kyoto University , Kyoto , Japan.

Background: There are limited data on the prevalence and burden of severe eosinophilic asthma (SEA) both in Japan and globally. This study aimed to assess the prevalence and burden of SEA in Japan.

Methods: This study was a retrospective, observational cohort analysis using health records or health insurance claims from patients with severe asthma treated at Kyoto University Hospital. Read More

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http://dx.doi.org/10.1080/02770903.2018.1534967DOI Listing
March 2019
1 Read

Dupilumab in patients with uncontrolled asthma: type 2 biomarkers might be predictors of therapeutic efficacy.

J Asthma 2019 Mar 1:1-3. Epub 2019 Mar 1.

a West China School of Medicine and West China Hospital , Sichuan University , Chengdu, Sichuan , China.

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http://dx.doi.org/10.1080/02770903.2018.1545857DOI Listing
March 2019
1 Read

Primary care clinician adherence with asthma guidelines: the National Asthma Survey of Physicians.

J Asthma 2019 Mar 1:1-13. Epub 2019 Mar 1.

c Division of Intramural Research , National Institute of Environmental Health Sciences, National Institutes of Health , Research Triangle Park , NC , USA.

Background And Objectives: Although primary care clinicians provide >60% of U.S. asthma care, no nationally representative study has examined variation in adherence among primary care groups to four cornerstone domains of the Expert Panel Report-3 asthma guidelines: assessment/monitoring, patient education, environmental assessment, and medications. Read More

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http://dx.doi.org/10.1080/02770903.2019.1579831DOI Listing

Asthma deaths in North Carolina: 1999-2016.

J Asthma 2019 Feb 27:1-9. Epub 2019 Feb 27.

e Department of Biostatistics, Brody School of Medicine , East Carolina University , Greenville , NC , USA.

Introduction: Despite the significant decline in overall death rates in the U.S. over the past decade, many asthma deaths could have been avoided. Read More

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http://dx.doi.org/10.1080/02770903.2019.1579830DOI Listing
February 2019
1 Read

Analysis of wheeze sounds during tidal breathing according to severity levels in asthma patients.

J Asthma 2019 Feb 27:1-13. Epub 2019 Feb 27.

c College of Engineering , AMA International University , Kingdom of Bahrain.

Objective: This study aimed to statistically analyze the behavior of time-frequency features in digital recordings of wheeze sounds obtained from patients with various levels of asthma severity (mild, moderate, and severe), and this analysis was based on the auscultation location and/or breath phase.

Method: Segmented and validated wheeze sounds were collected from the trachea and lower lung base (LLB) of 55 asthmatic patients during tidal breathing maneuvers and grouped into nine different datasets. The quartile frequencies F, F, F, F and F, mean frequency (MF) and average power (AP) were computed as features, and a univariate statistical analysis was then performed to analyze the behavior of the time-frequency features. Read More

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http://dx.doi.org/10.1080/02770903.2019.1576193DOI Listing
February 2019
1 Read

Inhaler training and asthma knowledge are associated with a higher proportion of patients with correct inhaler technique in young but not in elderly asthmatic patients.

J Asthma 2019 Feb 27:1-11. Epub 2019 Feb 27.

a NuESA - Health Environment Study Group, Faculty of Health Sciences , University of Beira Interior , Covilhã , Portugal.

Objective: Incorrect inhaler usage is frequent, particularly in elderly asthmatic patients. This study aimed at comparing inhaler technique errors and their determinants, as well inhaler technique self-perception versus real performance, between elderly and non-elderly asthmatics.

Methods: Cross-sectional assessment of 92 elderly and 100 non-elderly asthmatics followed at specialty clinics. Read More

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http://dx.doi.org/10.1080/02770903.2019.1582063DOI Listing
February 2019
2 Reads

Neighborhood air pollution and household environmental health as it relates to respiratory health and healthcare utilization among elderly persons with asthma.

J Asthma 2019 Feb 27:1-12. Epub 2019 Feb 27.

a Department of Family Medicine, College of Human Medicine , Michigan State University , Grand Rapids , Michigan , USA.

Objective: The study investigated the associations between fine particulate matter (PM; <2.5 μm in diameter), indoor environment, pulmonary function, and healthcare utilization in a vulnerable group of elderly persons with asthma. We hypothesized that environmental conditions were associated with adverse pulmonary health outcomes. Read More

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http://dx.doi.org/10.1080/02770903.2018.1545856DOI Listing
February 2019
2 Reads

Fluticasone furoate/vilanterol versus fluticasone propionate in patients with asthma and exercise-induced bronchoconstriction.

J Asthma 2019 Feb 22:1-10. Epub 2019 Feb 22.

h Firestone Institute for Respiratory Health, Hamilton, ON , Canada.

Objective: To investigate whether once-daily (OD) fluticasone furoate (FF)/vilanterol (VI) provides greater long-term protection from postexercise fall in forced expiratory volume in 1 s (FEV) than twice-daily (BD) fluticasone propionate (FP) in patients with asthma and exercise-induced bronchoconstriction.

Methods: A randomized, double-blind, crossover study was conducted in patients (aged 12-50 years) on low-/mid-dose maintenance inhaled corticosteroid. Following a 4-week run-in period (FP 250 µg BD), patients with a ≥ 20% decrease in postexercise FEV received FF/VI 100/25 µg OD or FP 250 µg BD for 2 weeks. Read More

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http://dx.doi.org/10.1080/02770903.2019.1579344DOI Listing
February 2019
1 Read

Differentiating non-responders from responders in children with moderate and severe asthma exacerbations.

J Asthma 2019 Feb 22:1-5. Epub 2019 Feb 22.

a Department of Pediatrics , Connecticut Children's Medical Center , Hartford , CT , USA.

Objective: Our goal was to assess factors associated with non-response to treatment in children presenting to the Emergency Department (ED) with moderate and severe asthma exacerbations.

Methods: A retrospective chart review was completed from 9/2014 to 2/2017 for patients with a discharge diagnosis of asthma exacerbation. The Modified Pulmonary Index Score (MPIS) was used to quantify illness acuity. Read More

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http://dx.doi.org/10.1080/02770903.2019.1579343DOI Listing
February 2019

Mepolizumab in adolescents with severe eosinophilic asthma not eligible for omalizumab: one center's early clinical experience.

J Asthma 2019 Feb 22:1-4. Epub 2019 Feb 22.

b School of Medicine , University of Glasgow , Glasgow , United Kingdom of Great Britain and Northern Ireland.

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http://dx.doi.org/10.1080/02770903.2019.1579833DOI Listing
February 2019

Eosinophil cell count in bronchoalveolar lavage fluid in early childhood wheezing: is it predictive of future asthma?

J Asthma 2019 Feb 22:1-7. Epub 2019 Feb 22.

d Department of Pediatric Pulmonology , Safra Children's Hospital, Sheba Medical Center, Tel Aviv University, Sackler Faculty of Medicine , Tel Aviv , Israel.

Objective: Increased eosinophil level in bronchoalveolar lavage fluid (BALF) characterizes asthma in school-age children and adults and has been suggested as a marker for disease severity and response to treatment. We aimed to investigate the occurrence and yield of BALF eosinophil cell count in preschool children with recurrent wheezing and its possible relation to future diagnosis of asthma.

Methods: BALF was retrospectively studied in young wheezy children and its relation to asthma at age 6 years was evaluated. Read More

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http://dx.doi.org/10.1080/02770903.2019.1579829DOI Listing
February 2019

Severe asthma and bronchiectasis.

J Asthma 2019 Feb 20:1-5. Epub 2019 Feb 20.

a Department of Pneumology , Hospital Universitario Central de Asturias , Oviedo , Spain.

Objective: The aim of our study was to determine the tomographic findings and prevalence of bronchiectasis in our population of patients with severe asthma, and to identify factors associated with the presence of bronchiectasis in these patients.

Materials And Methods: We retrospectively collected data from the medical histories of patients referred to the asthma unit of our hospital, with a diagnosis of severe asthma between 2015 and 2017. Patients with ABPA, cystic fibrosis, immunodeficiency or systemic disease were excluded. Read More

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http://dx.doi.org/10.1080/02770903.2019.1579832DOI Listing
February 2019
1 Read

Relationship between asthma status and antibody response pattern to 23-valent pneumococcal vaccination.

J Asthma 2019 Feb 20:1-10. Epub 2019 Feb 20.

h Department of Pediatric and Adolescent Medicine/Internal Medicine , Mayo Clinic , Rochester , MN , USA.

Objective: Asthma poses an increased risk for serious pneumococcal disease, but little is known about the influence of asthma status on the 23-valent serotype-specific pneumococcal antibody response. We examined differences in antibody titers between pre- and post-vaccination with 23-valent pneumococcal polysaccharide vaccine (PPSV-23) in relation to asthma status.

Methods: Asthma status was retrospectively ascertained by the Predetermined Asthma Criteria in an existing vaccine cohort through comprehensive medical record review. Read More

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http://dx.doi.org/10.1080/02770903.2019.1575394DOI Listing
February 2019

Exploring factors associated with health disparities in asthma and poorly controlled asthma among school-aged children in the U.S.

J Asthma 2019 Feb 7:1-14. Epub 2019 Feb 7.

f University of North Texas , Fort Worth , Texas , USA.

Objective: Certain populations suffer disproportionately from asthma and asthma morbidity. The objective was to provide a national descriptive profile of asthma control and treatment patterns among school-aged children (SAC: aged 6-17) in the U.S. Read More

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http://dx.doi.org/10.1080/02770903.2019.1571080DOI Listing
February 2019

The role of serum nuclear factor erythroid 2-related factor 2 in childhood bronchial asthma.

J Asthma 2019 Feb 7:1-6. Epub 2019 Feb 7.

c Neonatology, Kasr Alainy Faculty of Medicine , Cairo University , Cairo , Egypt.

Background: Asthma is one of the most common chronic airway disease of childhood. Poor asthma control has been associated with antioxidant deficiencies.

Objective: To assess the association of bronchial asthma in Egyptian children with serum nuclear factor erythroid 2-related factor2 (NRF2) and its relation to disease severity. Read More

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https://www.tandfonline.com/doi/full/10.1080/02770903.2019.1
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http://dx.doi.org/10.1080/02770903.2019.1571081DOI Listing
February 2019
12 Reads

Trends in the use of cigarettes, cigars, and marijuana among students with and without asthma, 2003-2017.

J Asthma 2019 Feb 7:1-7. Epub 2019 Feb 7.

c Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion , Centers for Disease Control and Prevention , Atlanta , GA , USA.

Aim: Asthma has symptoms that can be exacerbated by using combustible products such as tobacco and marijuana. This study assessed the prevalence and trends in current use of cigarettes, cigars, and marijuana among U.S. Read More

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http://dx.doi.org/10.1080/02770903.2019.1573254DOI Listing
February 2019

Role of technology in improving knowledge and confidence in asthma management in school staff.

J Asthma 2019 Feb 5:1-6. Epub 2019 Feb 5.

a Respiratory Department , Sydney Children's Hospital , Sydney , Australia.

Objective: To investigate the effectiveness of technology enabled learning in improving asthma first aid knowledge and self-confidence in providing asthma first aid to children in staff within a school setting.

Study Design: A prospective randomized parallel study using a pre and post test design was conducted across Metropolitan schools of New South Wales (NSW), Australia. School staff in selected schools were randomly assigned to receive first aid asthma management training via a self-directed multimedia eBook learning resource or standard face-to-face training. Read More

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http://dx.doi.org/10.1080/02770903.2019.1571087DOI Listing
February 2019
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Prevalence of symptoms of asthma and allergic rhinitis in children in Southern Brazil: a ten-year monitoring study.

J Asthma 2019 Feb 5:1-8. Epub 2019 Feb 5.

b Universidade Federal de Ciências da Saúde de Porto Alegre, Programa de Pós-Graduação em Patologia , Porto Alegre , RS , Brazil.

Objective: This study analyzes and describes trends in prevalence of asthma and rhinitis in children 6-7 years old living in Santo Ângelo, Brazil, by comparing data from 2007, 2012, and 2017.

Methods: The ISAAC (International Study of Asthma and Allergies in Childhood) standardized written questionnaire was used in a three cross-sectional survey. The questionnaire was applied between March and May of 2007, 2012 and 2017. Read More

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http://dx.doi.org/10.1080/02770903.2019.1573253DOI Listing
February 2019
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Filarial tropical pulmonary eosinophilia.

J Asthma 2019 Feb 5. Epub 2019 Feb 5.

b Dr DY Patil University , Pune , India.

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http://dx.doi.org/10.1080/02770903.2018.1561892DOI Listing
February 2019
3 Reads

Development and validation of the family management scale for children with asthma (FMSCA).

J Asthma 2019 Feb 4:1-11. Epub 2019 Feb 4.

a School of Nursing , Beijing University of Chinese Medicine , Beijing , China.

Objective: This study aims to develop and validate the Family Management Scale for Children with Asthma (FMSCA) in China context.

Methods: Based on the Family Management Style Framework (FMSF) model, an original 89 items were generated from literature review and interviews with 15 caregivers of children with asthma. The preliminary scale was refined to 82 items through two rounds of experts' evaluation and a pilot study, then administered to 329 caregivers of children with asthma for testing between April and July 2013. Read More

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http://dx.doi.org/10.1080/02770903.2019.1571085DOI Listing
February 2019
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1.828 Impact Factor

Respiratory tract infection-induced asthma exacerbations in adults with asthma: assessing predictors and outcomes.

J Asthma 2019 Feb 4:1-10. Epub 2019 Feb 4.

b Department of Clinical Pharmacy & Therapeutics, Faculty of Pharmacy , Applied Science Private University , Amman , Jordan.

Objective: To evaluate clinical and economic burden associated with respiratory tract infection (RTI)-induced asthma exacerbations and to identify risk factors associated with these exacerbations. Factors associated with these exacerbations are understudied and little information is available about consequent expenditures.

Methods: In this retrospective case-control study, medical records and pharmacy data in King Abdullah University Hospital in Northern Jordan were reviewed for adults with asthma aged 40 years and older, over the period 2013-2016. Read More

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http://dx.doi.org/10.1080/02770903.2019.1568454DOI Listing
February 2019
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Diagnostic value of fractional exhaled nitric oxide in cough-variant asthma: an updated meta-analysis.

J Asthma 2019 Feb 1:1-8. Epub 2019 Feb 1.

a Department of Respiratory , Peking University International Hospital , Beijing , China.

Objective: We aimed to evaluate the diagnostic value of fractional exhaled nitric oxide (FeNO) in cough-variant asthma (CVA) detection.

Methods: Relevant studies on the FeNO test in patients with CVA were retrieved from electronic databases including PubMed, Medline, Springer, Elsevier Science Direct, the Cochrane Library, and Google Scholar, up to August 2018. Meta-analysis for sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), and diagnostic odds ratio (DOR) of the FeNO test were conducted after extracting related data from the included studies. Read More

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http://dx.doi.org/10.1080/02770903.2019.1568452DOI Listing
February 2019
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Association between asthma, obesity, and health behaviors in African American youth.

J Asthma 2019 Jan 31:1-11. Epub 2019 Jan 31.

a Childhood Disparities Research Laboratory , University of Michigan , Ann Arbor , Michigan , USA.

Background: There is a clear relationship between obesity and asthma, with obesity recognized as a risk factor for asthma. There is mounting evidence, however, that asthma may predict obesity risk via behavioral pathways.

Objectives: The purpose of this study was to assess the cross-sectional relationships between asthma, body mass index (BMI) percentile, and behavioral factors including caloric intake, dietary inflammatory index, moderate-vigorous physical activity (MVPA), and sedentary time (SED) among African American adolescents. Read More

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http://dx.doi.org/10.1080/02770903.2019.1571083DOI Listing
January 2019
3 Reads