597,830 results match your criteria Joint Reduction Elbow Dislocation Posterior

Treatment of Periprosthetic Joint Infection in Total Knee Arthroplasty with a Temporary Intramedullary Nail: Is a Long or Short Nail Better?

J Knee Surg 2021 May 4. Epub 2021 May 4.

Center for Joint Preservation and Replacement, Rubin Institute for Advanced Orthopedics, Sinai Hospital of Baltimore, Baltimore, Maryland.

To our knowledge, no studies have compared postoperative outcomes between patients who received a temporary short or long intramedullary (IM) nail in the setting of infected total knee arthroplasty (TKA). Therefore, the aim of this study was to compare short-term outcomes for patients who underwent long or short IM nail insertion for treatment of periprosthetic knee infection. Specifically, we compared: (1) success rates; (2) patient reported/functional outcomes; and (3) complications between patients implanted with a short or a long IM nail following PJI of the knee. Read More

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Extensor hallucis longus muscle contracture after distal tibial physeal injury: A report of two cases.

Foot (Edinb) 2021 Apr 15;47:101802. Epub 2021 Apr 15.

Department of Orthopedic Surgery, Osaka Medical and Phamaceutical University, 2-7, Daigaku-machi, Takatsuki 569-8686, Japan. Electronic address:

Few studies have reported about isolated contracture in the extensor hallucis longus (EHL) muscle, but none of the EHL muscle contracture after distal tibial physeal injury. Two such cases in 16- and 14-year-old boys who underwent surgeries for distal physeal injury of the tibia at a previous hospital are presented. Extension contracture of the hallux appeared 1-2 months post-surgery. Read More

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Beaming in the Charcot foot: A case series with 12-month minimum follow-up.

Foot (Edinb) 2021 Apr 18;47:101814. Epub 2021 Apr 18.

Department of Orthopaedics and Trauma Surgery, 'Gregorio Marañón' University Hospital, Madrid, Spain. Electronic address:

Background: Charcot neuropathic arthropathy is a progressive degeneration of the weightbearing joints of the foot induced by denervation and disturbance of sensorial perception. This entity clinically behaves as a destructive fast-progressive arthropathy, resulting in loss of independent walking and often requiring amputation of the leg. This study analyzes our experience with midfoot realignment arthrodesis and stabilization by intramedullary beaming in patients with Charcot diabetic foot as a limb-sparing procedure. Read More

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A case report with review of literature of a rare variant of midfoot dislocations (mid-Chopart dislocation): Combined naviculo-cuneiform and calcaneo-cuboid dislocation.

Foot (Edinb) 2021 Apr 20;47:101806. Epub 2021 Apr 20.

Faculty of Medicine, Helwan University, Cairo, Egypt. Electronic address:

Closed midfoot and Chopart dislocations are uncommon injuries. Moreover, a combination of these dislocations is extremely rare. A 30-year-old male presented to our emergency department with mid-Chopart dislocation (combined naviculo-cuneiform and calcaneo-cuboid dislocation). Read More

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Does the length of the plate affect the failure rate of hallux MTP joint arthrodesis for severe hallux valgus?

Foot (Edinb) 2021 Jan 2;47:101773. Epub 2021 Jan 2.

Division of Foot and Ankle Surgery, Department of Orthopaedic Surgery, University of Virginia Health System, PO Box 801016 Charlottesville, VA, USA. Electronic address:

Purpose: The purpose of this study was to investigate the effect of the length of the dorsal locking plate on the failure rate of first MTP joint arthrodesis for severe hallux valgus deformities.

Methods: A retrospective review was conducted for all patients who underwent first MTP joint arthrodesis using solely a specific locked plating system (Depuy-Synthes, Raynham, MA) for severe hallux valgus deformities between January 2014 to June 2017. Patients were divided into subgroups according to the length of the plate and the failure rate was investigated. Read More

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January 2021

Targeted and nontargeted metabolomics analysis for determining the effect of storage time on the metabolites and taste quality of keemun black tea.

Food Chem 2021 Apr 24;359:129950. Epub 2021 Apr 24.

State Key Laboratory of Tea Plant Biology and Utilization, Anhui Agricultural University, Hefei 230036, China; International Joint Laboratory on Tea Chemistry and Health Effects of Ministry of Education, Anhui Agricultural University, Hefei 230036, China. Electronic address:

The black tea could be stored for a long time, and subsequently affects the flavor characteristics. In the present study, the effects of storage years (1, 2, 3, 4, 5, 10, 17 and 20 years) on the chemical profiling and taste quality of keemun black tea (KBT) were compared by metabolomics and quantitative sensory evaluation. The main polyphenols were degraded during the storing, especially 10-year storage, but caffeine and theobromine were stable. Read More

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Stable and recyclable FeC@CN catalyst supported on carbon felt for efficient activation of peroxymonosulfate.

J Colloid Interface Sci 2021 Apr 20;599:219-226. Epub 2021 Apr 20.

College of Geography and Environmental Science, Zhejiang Normal University, Jinhua 321004, China. Electronic address:

Stable and recyclable catalysts are crucial to the peroxymonosulfate (PMS) based advanced oxidation process (AOPs) for wastewater treatment. Herein, nitrogen-rich carbon wrapped FeC (FeC@CN) on carbon felt (CF) substrate was synthesized by using Prussian blue (PB) loaded CF as the precursors. The obtained FeC@CN/CF catalyst was applied for degradation of bisphenol A (BPA) via the heterogeneous catalytic activation of PMS. Read More

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Roles and performance enhancement of feed spacer in spiral wound membrane modules for water treatment: A 20-year review on research evolvement.

Water Res 2021 Apr 15;198:117146. Epub 2021 Apr 15.

State Key Joint Laboratory of Environment Simulation and Pollution Control, School of Environment, Tsinghua University, Beijing, 100084, China; Research and Application Center for Membrane Technology, School of Environment, Tsinghua University, Beijing 100084, China. Electronic address:

Membrane technologies have been widely applied in water treatment, wastewater reclamation and seawater desalination. Feed spacer present in spiral wound membrane (SWM) modules plays a pivotal role in creating flow channels, promoting fluid mixing and enhancing mass transfer. However, it induces the increase of feed channel pressure (FCP) drop and localized stagnant zones that provokes membrane fouling. Read More

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The nuclear localization sequence of the epigenetic factor RYBP binds to human importin α3.

Biochim Biophys Acta Proteins Proteom 2021 May 1:140670. Epub 2021 May 1.

Institute for Biocomputation and Physics of Complex Systems (BIFI), Joint Units IQFR-CSIC-BIFI, GBsC-CSIC-BIFI, Universidad de Zaragoza, 50018 Zaragoza, Spain; Instituto de Investigación Sanitaria Aragón (IIS Aragón), 50009 Zaragoza, Spain; Fundación ARAID, Government of Aragón, 50018 Zaragoza, Spain; Departamento de Bioquímica y Biología Molecular y Celular, Universidad de Zaragoza, 50009 Zaragoza, Spain; Centro de Investigación Biomédica en Red en el Área Temática de Enfermedades Hepáticas y Digestivas (CIBERehd), 28006 Madrid, Spain.

RYBP (Ring1 and YY1 binding protein, UniProt ID: Q8N488) is an epigenetic factor with a key role during embryonic development; it does also show an apoptotic function and an ubiquitin binding activity. RYBP is an intrinsically disordered protein (IDP), with a Zn-finger domain at its N-terminal region, which folds upon binding to DNA. It is predicted that RYBP has a nuclear localization sequence (NLS), comprising residues Asn58 to Lys83, to allow for nuclear translocation. Read More

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Ultrashort echo time adiabatic T (UTE-Adiab-T) is sensitive to human cadaveric knee joint deformation induced by mechanical loading and unloading.

Magn Reson Imaging 2021 May 1. Epub 2021 May 1.

Department of Radiology, University of California, San Diego, CA, USA.

Purpose: The development of ultrashort echo time (UTE) MRI sequences has led to improved imaging of tissues with short T relaxation times, such as the deep layer cartilage and meniscus. UTE combined with adiabatic T preparation (UTE-Adiab-T) is an MRI measure with low sensitivity to the magic angle effect. This study aimed to investigate the sensitivity of UTE-Adiab-T to mechanical load-induced deformations in the tibiofemoral cartilage and meniscus of human cadaveric knee joints. Read More

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Bone union status of all osteotomy sites one year after curved periacetabular osteotomy based on computed tomography.

Orthop Traumatol Surg Res 2021 May 1:102955. Epub 2021 May 1.

Department of Orthopaedic Surgery, Fukuoka University Faculty of Medicine, 7-45-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan. Electronic address:

Background: Curved periacetabular osteotomy (CPO) is a joint-preservation surgery to treat acetabular dysplasia. It is performed via an anterior approach with the osteotomy of the anterosuperior iliac spine (ASIS). One of the complications associated with CPO includes non-union of the osteotomy sites. Read More

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Prevalence and interference of chronic pain among people with haemophilia: A systematic review and meta-analysis.

J Pain 2021 May 1. Epub 2021 May 1.

Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal; ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal. Electronic address:

Chronic pain is a common condition among people with haemophilia (PWH), associated with joint deterioration due to repeated joint bleeds. This systematic review and meta-analysis aimed to determine the prevalence of chronic pain due to haemophilia and to analyze its interference in the lives of patients. A systematic search was performed in May and June 2019 and updated in February 2021, using PubMed, EMBASE, Web of Science and SciElo. Read More

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Measuring quality of family planning counselling and its effects on uptake of contraceptives in public health facilities in Uttar Pradesh, India: A cross-sectional analysis.

PLoS One 2021 4;16(5):e0239565. Epub 2021 May 4.

Division of Global Public Health, Center on Gender Equity and Health, University of California, San Diego School of Medicine, La Jolla, CA, United States of America.

Background: Quality of care in family planning traditionally focuses on promoting awareness of the broad array of contraceptive options rather than on the quality of interpersonal communication offered by family planning (FP) providers. There is a growing emphasis on person-centered contraceptive counselling, care that is respectful and focuses on meeting the reproductive needs of a couple, rather than fertility regulation. Despite the increasing global focus on person-centered care, little is known about the quality of FP care provided in low- and middle- income countries like India. Read More

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Chronic active non-lethal human-type tuberculosis in a high royal Bavarian officer of Napoleonic times-a mummy study.

PLoS One 2021 4;16(5):e0249955. Epub 2021 May 4.

Institute of Legal Medicine, Ludwig-Maximilians University (LMU), Munich, Germany.

In paleopathology, morphological and molecular evidence for infection by mycobacteria of the M. tuberculosis complex (MTC) is frequently associated with early death. In the present report, we describe a multidisciplinary study of a well-preserved mummy from Napoleonic times with a long-standing tuberculous infection by M. Read More

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Pediatric Acetabular Osteomyelitis Treated With Hip Arthroscopy.

J Am Acad Orthop Surg Glob Res Rev 2021 May 4;5(5):e21.00011. Epub 2021 May 4.

From the Division of Orthopaedic Surgery, Western University, London, Ontario, Canada (Dr. Lovse); the Division of Orthopaedic Surgery, University of Ottawa, Ottawa, Ontario, Canada (Dr. Coupal); the Division of Orthopaedic Surgery, CHEO, Ottawa, Ontario, Canada (Dr. Tice, Dr. Carsen); and the Division of Infectious Diseases, CHEO, Ottawa, Ontario, Canada (Dr. Le Saux).

Osteomyelitis of the acetabulum is a rare condition accounting for only 12% of pelvic osteomyelitis cases. This report describes a previously healthy 10-year-old girl with subacute acetabular osteomyelitis and subsequent development of secondary septic arthritis of the hip. The patient presented with 3 weeks of groin pain, elevated erythrocyte sedimentation rate and C-reactive protein, synovial thickening of the hip on ultrasonography and diffuse signal uptake in the acetabulum on magnetic resonance imaging. Read More

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JAS-GAN: Generative Adversarial Network Based Joint Atrium and Scar Segmentation on Unbalanced Atrial Targets.

IEEE J Biomed Health Inform 2021 May 4;PP. Epub 2021 May 4.

Automated and accurate segmentation of the left atrium (LA) and atrial scars from late gadolinium-enhanced cardiac magnetic resonance (LGE CMR) images are in high demand for quantifying atrial scars. The previous quantification of atrial scars relies on a two-phase segmentation for LA and atrial scars due to their large volume difference (unbalanced atrial targets). In this paper, we propose an inter-cascade generative adversarial network, namely JAS-GAN, to segment the unbalanced atrial targets from LGE CMR images automatically and accurately in an end-to-end way. Read More

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An Immersive Computer-Mediated Caregiver-Child Interaction System for Young Children with Autism Spectrum Disorder.

IEEE Trans Neural Syst Rehabil Eng 2021 May 4;PP. Epub 2021 May 4.

Autism Spectrum Disorder (ASD) affects 1 in 54 children in the United States. A core social communication skill negatively impacted by ASD is joint attention (JA), which influences the development of language, cognitive, and social skills from infancy onward. Although several technology-based JA studies have shown potential, they primarily focus on response to joint attention (RJA). Read More

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Knockdown of hsa_circ_0134111 alleviates the symptom of osteoarthritis via sponging microRNA-224-5p.

Cell Cycle 2021 May 4:1-15. Epub 2021 May 4.

Department of Orthopedics, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, P.R. China.

The relevance of circular RNAs (circRNAs) has been indicated in the progression of various diseases. Nevertheless, the precise function of circRNAs in osteoarthritis (OA) remains to be established. Therefore, we aimed to investigate changes in the expression of a specific circRNA, hsa_circ_0134111 (circ_PDE1C) and predict its functions in OA. Read More

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Prediction of stroke-associated pneumonia by the A2DS2, AIS-APS, and ISAN scores: a systematic review and meta-analysis.

Expert Rev Respir Med 2021 May 4. Epub 2021 May 4.

Department of Neurosurgery, Zhuji People's Hospital of Zhejiang Province, Shaoxing 312000, Zhejiang Province, P.R. China.

Background: Different scoring systems (A2DS2, AISAPS, ISAN) have been designed to predict the risk of in-hospital stroke-associated pneumonia (SAP). Studies have assessed the accuracy of these scores for predicting SAP. We performed this meta-analysis to consolidate the evidence on the predictive accuracies for SAP of the A2DS2, AISAPS, and ISAN scores. Read More

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Muscle co-contraction in an upper limb musculoskeletal model: EMG-assisted vs. standard load-sharing.

Comput Methods Biomech Biomed Engin 2020 Oct 14:1-14. Epub 2020 Oct 14.

Laboratory of Biomechanical Orthopedics, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.

Estimation of muscle forces in over-actuated musculoskeletal models involves optimal distributions of net joint moments among muscles by a standard load-sharing scheme (SLS). Given that co-contractions of antagonistic muscles are counterproductive in the net joints moments, SLS might underestimate the co-contractions. Muscle co-contractions play crucial roles in stability of the glenohumeral (GH) joint. Read More

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October 2020

Validation of a Risk Calculator to Personalize Graft Choice and Reduce Rupture Rates for Anterior Cruciate Ligament Reconstruction.

Am J Sports Med 2021 May 4:3635465211010798. Epub 2021 May 4.

Faculty of Health Sciences, Western University, London, Ontario, Canada.

Background: Anterior cruciate ligament reconstructions (ACLRs) fail at an alarmingly high rate in young active individuals. The Multicenter Orthopaedic Outcomes Network (MOON) knee group has developed an autograft risk calculator that uses patient characteristics and lifestyle to predict the probability of graft rupture if the surgeon uses a hamstring tendon (HT) or a bone-patellar tendon-bone (BPTB) graft to reconstruct the ligament. If validated, this risk calculator can be used during the shared decision-making process to make optimal ACLR autograft choices and reduce rupture rates. Read More

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Psychometric properties of the Child Eating Behavior Questionnaire (CEBQ) in school age children with overweight and obesity: A proposed three-factor structure.

Pediatr Obes 2021 May 4:e12795. Epub 2021 May 4.

Department of Pediatrics, University of California San Diego, La Jolla, California, USA.

Background: Obesity in youth is a significant public health concern, with eating behaviors being a major contributor. The Child Eating Behavior Questionnaire (CEBQ) was developed to evaluate the appetitive characteristics of young children, across a myriad of eating domains. Despite the breadth of its use, the psychometric properties of the measure in children with overweight/obesity (OW/OB), particularly treatment seeking youth, remains largely unexplored. Read More

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Clinical Results of Acetabular Fracture via the Pararectus versus Ilioinguinal Approach.

Orthop Surg 2021 May 4. Epub 2021 May 4.

Department of Orthopaedics, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.

Objective: To compare the clinical efficacy of pararectus and ilioinguinal approach in the treatment of acetabular fractures.

Methods: A retrospective analysis of the clinical data of 60 patients with acetabular fractures treated by the pararectus approach or the ilioinguinal approach from January 2016 to January 2019 was performed to record all data by comparing the length of the surgical incision, the time to expose the fracture and the amount of blood loss during the operation. Patients were routinely followed up at 1, 6 and 12 months postoperatively. Read More

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PTH-induced EndMT via miR-29a-5p/GSAP/Notch1 pathway contributed to valvular calcification in rats with CKD.

Cell Prolif 2021 May 4:e13018. Epub 2021 May 4.

Institute of Nephrology, School of Medicine, Zhong Da Hospital, Southeast University, Nanjing, China.

Background: Endothelial-to-mesenchymal transition (EndMT) is a common pathophysiology in valvular calcification (VC) among non-chronic kidney disease (CKD) patients. However, few studies were investigated in CKD-induced VC. Parathyroid hormone (PTH) was considered to be an important component of EndMT in CKD-induced cardiovascular diseases. Read More

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Assessment of accuracy of an imageless hand-held robotic-assisted system in component positioning in total knee replacement: a prospective study.

J Robot Surg 2021 May 4. Epub 2021 May 4.

Department of Orthopedics, Lokmanya Hospital, Nigdi, Pradhikaran, Pune, India.

In recent years, robotic technology is becoming more pervasive in joint arthroplasty. The role of robotics in joint replacement surgery is to bring precision and accuracy in bone preparation, implant positioning and soft tissue balancing. However, there is yet to be a study conducted to determine the accuracy of bone preparation done by a new robotic system. Read More

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[Economics and management of CAR T- cell therapy : Status quo and future perspectives].

Internist (Berl) 2021 May 4. Epub 2021 May 4.

Klinik I für Innere Medizin, Uniklinik Köln und Centrum für Integrierte Onkologie Aachen Bonn Köln Düsseldorf, Köln, Deutschland.

Background: Virtually no other topic has attracted more attention in oncology in recent years than chimeric antigen receptor (CAR) T‑cell therapy (CAR T). On the one hand it opens up completely new treatment options for cancer patients, while on the other it generates treatment costs exceeding € 300,000 per treatment.

Objectives: The aim of this work is to analyze the economic, procedural and organizational challenges of CAR T‑cell therapy from the perspective of the service provider, the cost-bearer and the pharmaceutical manufacturer. Read More

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[A multidimensional v-shaped distalizing osteotomy of the tibial tuberosity with a proximal buttress ("coffin-shaped" osteotomy)].

Orthopade 2021 May 4. Epub 2021 May 4.

Dept. für Orthopädie und Traumatologie, Medizinische Universität Innsbruck, Anichstraße 35, 6020, Innsbruck, Österreich.

The aim of the intervention presented is a distalization of the tibial tuberosity. It is indicated in patients with symptomatic patella alta, i.e. Read More

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ICD-10 Coding of Musculoskeletal Conditions in the Veterans Health Administration.

Pain Med 2021 May 3. Epub 2021 May 3.

Pain Research, Informatics, Multimorbidities, and Education (PRIME) Center, VA Connecticut Healthcare System, West Haven, CT.

Objective: We describe the most frequently used musculoskeletal diagnoses in Veterans Health Administration (VHA) care. We report the number of visits and patients associated with common musculoskeletal ICD-10 codes and compare trends across primary and specialty care settings.

Design: Secondary analysis of a longitudinal cohort study. Read More

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Effect of Half-Dose vs Stable-Dose Conventional Synthetic Disease-Modifying Antirheumatic Drugs on Disease Flares in Patients With Rheumatoid Arthritis in Remission: The ARCTIC REWIND Randomized Clinical Trial.

JAMA 2021 May;325(17):1755-1764

Division of Rheumatology and Research, Diakonhjemmet Hospital, Oslo, Norway.

Importance: Sustained remission has become an achievable goal for patients with rheumatoid arthritis (RA) receiving conventional synthetic disease-modifying antirheumatic drugs (csDMARDs), but how to best treat patients in clinical remission remains unclear.

Objective: To assess the effect of tapering of csDMARDs, compared with continuing csDMARDs without tapering, on the risk of flares in patients with RA in sustained remission.

Design, Setting, And Participants: ARCTIC REWIND was a multicenter, randomized, parallel, open-label noninferiority study conducted in 10 Norwegian hospital-based rheumatology practices. Read More

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