3,140 results match your criteria Joint Bone Spine [Journal]


Esophagus type cervical spondylosis.

Authors:
Hecheng Ma Si Meng

Joint Bone Spine 2019 Apr 11. Epub 2019 Apr 11.

Department of Orthopedics, Qilu Hospital of Shandong University, Shandong University, Jinan, 250012, China.

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http://dx.doi.org/10.1016/j.jbspin.2019.04.003DOI Listing
April 2019
1 Read

Uptrend in mortality from systemic connective tissue diseases: a joinpoint regression analysis among the general population of Brazil, 1996-2016.

Joint Bone Spine 2019 Apr 11. Epub 2019 Apr 11.

Disciplina de Reumatologia, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil.

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http://dx.doi.org/10.1016/j.jbspin.2019.03.010DOI Listing

Is prediction of clinical response to methotrexate in individual rheumatoid arthritis patients possible? A systematic literature review.

Joint Bone Spine 2019 Apr 11. Epub 2019 Apr 11.

Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, PO Box 85500, 3508 GA Utrecht, the Netherlands.

Objectives: To identify, by a systematic literature review, predictors of clinical response to methotrexate treatment in rheumatoid arthritis patients, which would facilitate personalised treatment.

Methods: PubMed and Embase databases were searched for original articles. Additionally, congress abstracts of European League Against Rheumatism and American College of Rheumatology annual meetings of the past 2 years were screened. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.04.002DOI Listing
April 2019
1 Read

There is no season for infectious spondylodiscitis.

Joint Bone Spine 2019 Apr 11. Epub 2019 Apr 11.

Department of Rheumatology, CHU Clermont ferrand, 58 rue Montalembert, 63003 Clermont Ferrand CEDEX 1, France.

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http://dx.doi.org/10.1016/j.jbspin.2019.04.001DOI Listing

Biological secondary contributors to osteoporosis in fractured patients, is an early systematic assay relevant?

Joint Bone Spine 2019 Apr 9. Epub 2019 Apr 9.

Rheumatology Department, Cochin Hospital, 75014 Paris, France; INSERM U1153, 75014 Paris France. Electronic address:

Objective: To evaluate the prevalence of biological abnormalities leading to secondary osteoporosis in recently fractured patients.

Methods: Adults older than 50, hospitalized for a nonvertebral fracture from July 2015 to October 2016, were assessed for bone fragility contributors in the Orthopedics Department. Bone mineral density (BMD) measurements and Vertebral Fracture assessment (VFA) were performed within 3 months. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.03.009DOI Listing
April 2019
1 Read

Rate of remission among rheumatoid arthritis patients being treated by rheumatologists in routine practice.

Joint Bone Spine 2019 Mar 27. Epub 2019 Mar 27.

Department of rheumatology, university hospital Gabriel-Montpied 58, rue Montalembert 63003 Clermont-Ferrand cedex 1, France.

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http://dx.doi.org/10.1016/j.jbspin.2019.03.006DOI Listing
March 2019
3 Reads

Isolated muscle hypertrophy revealing diffuse large B-cell lymphoma.

Joint Bone Spine 2019 Mar 27. Epub 2019 Mar 27.

Université Côte d'Azur, faculté de médecine de Nice, 06200 Nice, France; Service de médecine interne, CHU de l'Archet, Nice, 06200 Nice, France. Electronic address:

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http://dx.doi.org/10.1016/j.jbspin.2019.03.007DOI Listing
March 2019
4 Reads

Polymyalgia rheumatica occurrence under multikinase inhibitors (sorafenib and erlotinib) treatment.

Joint Bone Spine 2019 Mar 27. Epub 2019 Mar 27.

Service de rhumatologie, CHRU de Besançon, 25030 Besançon, France; EA 4266 "pathogens and inflammation/EPILAB" université Bourgogne Franche-Comté, 25000 Besançon, France.

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http://dx.doi.org/10.1016/j.jbspin.2019.03.005DOI Listing
March 2019
4 Reads

Early clinical response and long-term radiographic progression in recent-onset rheumatoid arthritis: Clinical remission within six months remains the treatment target.

Joint Bone Spine 2019 Mar 27. Epub 2019 Mar 27.

Université Catholique de Louvain, Institut de Recherche Expérimentale et Clinique (IREC), 1200 Bruxelles, Belgium; Service de rhumatologie, Cliniques universitaires Saint-Luc, 1200 Bruxelles, Belgium. Electronic address:

Objectives: The primary objective was to evaluate the correlation between 5-year radiographic structural disease progression and early clinical remission in recent-onset rheumatoid arthritis (RA). The secondary objective was to assess the correlation between erosion development in joints free of damage at baseline and early clinical remission.

Methods: A single-center retrospective study was performed in 133 patients meeting ACR criteria for RA of recent onset. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.03.008DOI Listing
March 2019
2 Reads

Associations of hyperuricemia, gout, and UA-lowering therapy with the risk of fractures: a meta-analysis of observational studies.

Joint Bone Spine 2019 Mar 22. Epub 2019 Mar 22.

Division of Orthopedic Surgery, Affiliated Hospital of Qinghai University, 810001, Xining, Qinghai Province, China. Electronic address:

Objective: A systematic review and meta-analysis were conducted to investigate the associations of hyperuricemia, gout, and uric acid (UA)-lowering therapy with the risk of fractures.

Methods: Electronic searches on PubMed, the Cochrane Library, and Embase were conducted from inception to January 2, 2019. Observational studies assessing the effects of hyperuricemia, gout, and UA-lowering therapy on fractures were included in the meta-analysis. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.03.003DOI Listing
March 2019
2 Reads

Knee replacement incidence and social deprivation: results from a French ecological study.

Joint Bone Spine 2019 Mar 22. Epub 2019 Mar 22.

University hospital centre of Caen, department of rheumatology, Caen, 14000, France; University of Caen Normandie, medical school, Caen, 14000, France. Electronic address:

Objectives: Temporal and geographic variations in knee osteoarthritis (OA) incidence occur worldwide. Regional variations also exist for socioeconomic status. We analyzed the association between socioeconomic deprivation (SED) and knee replacement (KR) incidence and assessed the proportion of KR associated with affluence. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.03.004DOI Listing
March 2019
2 Reads

Destructive arthropathy of the shoulder complicating a cervical ependymoma.

Authors:
Zeineb Alaya

Joint Bone Spine 2019 Mar 16. Epub 2019 Mar 16.

Service de médecine interne, hôpital universitaire Mohamed-Tahar-Maamouri de Nabeul, 8000 Nabeul, Tunisia. Electronic address:

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http://dx.doi.org/10.1016/j.jbspin.2019.03.002DOI Listing

Epidural corticosteroid injections: Still credible?

Joint Bone Spine 2019 Mar 9. Epub 2019 Mar 9.

Service de Radiologie, Hôpital Lariboisière, 75475 Paris, France.

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https://linkinghub.elsevier.com/retrieve/pii/S1297319X193004
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http://dx.doi.org/10.1016/j.jbspin.2019.03.001DOI Listing
March 2019
1 Read

Rare diseases that mimic Systemic Lupus Erythematosus (Lupus mimickers).

Joint Bone Spine 2019 Mar 26;86(2):165-171. Epub 2018 Oct 26.

Centre national de référence des maladies autoimmunes et systémiques rares Est Sud-Ouest (RESO)-LUPUS, 67000 Strasbourg, France; Service de rhumatologie, hôpitaux universitaires de Strasbourg, 67098 Strasbourg, France; Université de Strasbourg, Inserm UMR-S 1109, 67000 Strasbourg, France. Electronic address:

Several conditions have clinical and laboratory features that can mimic those present in Systemic Lupus Erythematosus (SLE). Some of these "SLE mimickers" are very common, such as rosacea which can be mistaken for the butterfly rash, while others such as Kikuchi disease, type-1 interferonopathies, Castleman's disease, prolidase deficiency, angioimmunoblastic T-cell lymphoma, Evans' syndrome in the context of primary immune deficiencies and the autoimmune lymphoproliferative syndrome are exceptionally uncommon. A proper diagnosis of SLE must therefore be based upon a complete medical history as well as on the adequate constellation of clinical or laboratory findings. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1297319X183042
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http://dx.doi.org/10.1016/j.jbspin.2018.10.007DOI Listing
March 2019
10 Reads

The effect of periodontal treatment on patients with rheumatoid arthritis: The ESPERA randomised controlled trial.

Joint Bone Spine 2019 Feb 26. Epub 2019 Feb 26.

Paul Sabatier University, Dental Faculty, Toulouse University Hospital (CHU de Toulouse), 31062 Toulouse, France; Department of epidemiology and public health, Dental Faculty, 31062 Toulouse, France; Division of oral health and society, faculty of dentistry, McGill university, Montreal, Quebec H3A 0C7, Canada.

Objectives: To assess the effect of periodontal treatment on clinical and biochemical parameters of rheumatoid arthritis (RA) and quality of life (QoL) in patients with moderately active RA who were diagnosed with periodontitis.

Methods: In this open-label randomised controlled trial, RA subjects (n = 22) were allocated to "immediate" or "delayed" periodontal treatment (full-mouth non-surgical scaling and root planing, systemic antibiotics, and oral hygiene instructions). The main outcome was the 3-month change on the Disease Activity Score 28 based on the Erythrocyte Sedimentation Rate (DAS28-ESR). Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.02.006DOI Listing
February 2019
4 Reads

Motivational interviewing to improve treatment adherence.

Joint Bone Spine 2019 Feb 22. Epub 2019 Feb 22.

Service de rhumatologie, hôpital Saint Antoine, AP-HP, 184, rue du Faubourg-Saint-Antoine, 75012 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.jbspin.2019.02.005DOI Listing
February 2019

Ultrasound and clinical features of hip involvement in patients with gout.

Joint Bone Spine 2019 Feb 16. Epub 2019 Feb 16.

Università Politecnica delle Marche, Clinica Reumatologica, Dipartimento di Scienze Cliniche e Molecolari, Ancona, 60126, Italy.

Objectives: To investigate the prevalence of the ultrasound findings indicative of monosodium urate crystal deposits at the hip joint in patients with gout and to explore the association between the ultrasound findings and the clinical and serological features.

Methods: Bilateral ultrasound assessment of the hip joint was carried out in 40 consecutive patients with gout, diagnosed according to the latest Gout American College of Rheumatology/European League Against Rheumatism classification criteria, and 25 disease controls. Ultrasound evidence of crystal deposits was obtained using the Outcome Measures in Rheumatology definitions: hip intra-articular aggregates and/or tophi, and "double contour" sign over the hyaline cartilage of the femoral head. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.027DOI Listing
February 2019
1 Read
2.901 Impact Factor

Complex regional pain syndrome secondary to everolimus: Two cases.

Joint Bone Spine 2019 Feb 15. Epub 2019 Feb 15.

Centre de rhumatologie, hôpital Pierre-Paul-Riquet, CHU de Toulouse, place du Dr-Baylac, TSA 40 031, 31059 Toulouse cedex 9, France; Centre de physiopathologie Toulouse Purpan, Inserm UMR 1043, CHU de Purpan, BP 3028, 31024 Toulouse cedex 3, France.

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http://dx.doi.org/10.1016/j.jbspin.2019.02.003DOI Listing
February 2019
1 Read

Geoepidemiology of Sjögren's syndrome in Latin America.

Joint Bone Spine 2019 Feb 16. Epub 2019 Feb 16.

Center for Autoimmune Diseases Research (CREA), School of Medicine and Health Sciences, Universidad del Rosario, Bogota, Colombia. Electronic address:

Objective: To evaluate the geoepidemiology of Sjögren's syndrome (SS) in Latin America.

Methods: This was a three phase study in which original data from a Colombian cohort of patients with SS is presented, followed by a systematic review of Colombian and Latin American studies. Lastly, the geoepidemiology of SS in Latin America was assessed by comparing the clinical characteristics of the region with those of the rest of the world by means of a meta-analysis approach. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.02.004DOI Listing
February 2019
6 Reads
2.901 Impact Factor

Single tumor-like tophus.

Joint Bone Spine 2019 Feb 14. Epub 2019 Feb 14.

Service de rhumatologie, CHU de Hautepierre, 67000 Strasbourg, France.

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http://dx.doi.org/10.1016/j.jbspin.2019.02.002DOI Listing
February 2019

Reply to the comment of Sartorelli et al. "Diagnostic approach and novel therapeutic option for cardiac inflammatory disorders".

Joint Bone Spine 2019 Feb 11. Epub 2019 Feb 11.

Université Paris Diderot, Sorbonne Paris Cité, UFR de Médecine, 75025 Paris, France; AP-HP, Service de Rhumatologie, Hôpital Bichat, 75018 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.jbspin.2019.01.026DOI Listing
February 2019
1 Read

Assessment of major salivary gland size in primary Sjögren's syndrome: Comparison between clinical examination and ultrasonography.

Joint Bone Spine 2019 Feb 11. Epub 2019 Feb 11.

Service de rhumatologie, centre national de référence des maladies auto-immunes rares de l'adulte CERAINO, CHU de Brest, 29200 Brest, France; UMR1227, lymphocytes B et autoimmunité, université de Brest, Inserm, LabEx IGO, 29200 Brest, France.

Objective: Parotidomegaly is a criterion of the EULAR Primary Sjögren Syndrome Disease Activity Index (ESSDAI). The cut-off value was set at 3 cm in length for the parotid gland, 2 cm for the submandibular glands. However, clinical appreciation of salivary glands size remains hazardous. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.025DOI Listing
February 2019

The management of osteogenesis imperfecta in adults: state of the art.

Joint Bone Spine 2019 Feb 8. Epub 2019 Feb 8.

Service de médecine physique et de rééducation, 42270 Saint-Priest-en-Jarez, France.

Osteogenesis imperfecta (OI) is a genetic disease whose clinical phenotype and severity vary considerably. The increased risk of fractures due to bone fragility persists in adulthood, notably after 40 years of age, albeit at a lower level than during growth. Adults with OI require periodic evaluations of the other manifestations of OI including hearing loss, respiratory impairments, ocular and dental abnormalities, and cardiovascular disease. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.02.001DOI Listing
February 2019
8 Reads

Diagnostic approach and novel therapeutic option for cardiac inflammatory disorders. Comment on "Antisynthetase syndrome and cardiac involvement: a rare association" by Meudec et al. Joint Bone Spine 2018. doi: 10.1016/j.jbspin.2018.09.019.

Joint Bone Spine 2019 Feb 7. Epub 2019 Feb 7.

Unit of Immunology, Rheumatology, Allergy and Rare diseases, IRCCS San Raffaele Hospital, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1016/j.jbspin.2019.01.021DOI Listing
February 2019
1 Read

Assessment of the adherence to disease-modifying drugs in patients with chronic inflammatory rheumatic diseases: Results of a survey of 1594 patients.

Joint Bone Spine 2019 Feb 7. Epub 2019 Feb 7.

Département rhumatologie, hôpital Cochin, 75014 Paris, France; Inserm (U1153), clinical epidemiology and biostatistics, PRES Sorbonne Paris-Cité, 75014 Paris, France.

Objectives: a) to describe the self-reported adherence to disease modifying drugs (DMARDs) (methotrexate and biological DMARDs) among patients with chronic inflammatory rheumatic diseases (CIRDs); b) to assess factors associated with non-adherence.

Methods: An observational, cross-sectional, nationwide study was conducted through the use of an electronic survey, which was released via patient organizations in France to rheumatic patients. The main outcome was the rate of non-adherence to DMARDs, which was evaluated with the following question "Have you ever tried to stop or space out your treatment in contrast to what was planned with your doctor?" A positive answer was considered "low adherent". Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.023DOI Listing
February 2019
2 Reads

Exploratory study of adalimumab in twelve patients with chronic low back pain associated with Modic I changes.

Joint Bone Spine 2019 Feb 7. Epub 2019 Feb 7.

Department of rheumatology, HFR Fribourg-Cantonal Hospital, 1708 Fribourg, Switzerland.

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http://dx.doi.org/10.1016/j.jbspin.2019.01.024DOI Listing
February 2019
4 Reads

The risk of Sjogren's syndrome in the older adults with gout: A medicare claims study.

Joint Bone Spine 2019 Feb 7. Epub 2019 Feb 7.

Department of Medicine at the School of Medicine, University of Alabama at Birmingham, 1720 Second avenue South, Birmingham, 35294-0022 AL, USA.

Objectives: In the absence of previous studies, our objective was to assess whether gout was associated with an increase or decrease in the risk of Sjogren's Syndrome (SS) in older adults, 65 years or older.

Methods: We used the 5% Medicare claims from 2006-2012. A multivariable Cox regression model assessed the association of gout with incident SS adjusting for age, sex, race, Charlson-Romano comorbidity index, and the use of medications for cardiovascular diseases (statins, beta-blockers, diuretics, ACE-inhibitors) and gout (allopurinol, febuxostat). Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.022DOI Listing
February 2019
1 Read

Curative treatment of prosthetic joint infection in patients younger than 80 vs. 80 or older.

Joint Bone Spine 2019 Feb 6. Epub 2019 Feb 6.

Centre de référence des infections ostéo-articulaires complexes, groupe hospitalier Diaconesses-Croix Saint-Simon, 125, rue d'Avron, Paris 75020, France; Service de chirurgie osseuse et traumatologique, groupe hospitalier Diaconesses-Croix Saint-Simon, 125, rue d'Avron, Paris 75020, France.

Objective: Prosthetic joint infection (PJI) is a serious complication of joint replacement surgery. The major pharmacological and surgical treatments required by PJI increase the risk of peri-operative complications in elderly patients. The increase in life expectancy combined with procedural advances make these treatments possible even in the oldest patients. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.017DOI Listing
February 2019
6 Reads

Bortezomib improved the joint manifestations of rheumatoid arthritis in three patients.

Joint Bone Spine 2019 Feb 6. Epub 2019 Feb 6.

Service de rhumatologie, centre hospitalier Jean-Rougié Cahors 46000, France.

The proteasome inhibitor bortezomib has been proven effective in the treatment of multiple myeloma. We report on 3 patients with rheumatoid arthritis and multiple myeloma in whom bortezomib therapy was associated with improvements in the joint manifestations. The contribution to this effect of the concomitant glucocorticoid therapy is discussed. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1297319X193001
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http://dx.doi.org/10.1016/j.jbspin.2019.01.019DOI Listing
February 2019
12 Reads

Statins, myalgia, and rhabdomyolysis.

Authors:
Anne Tournadre

Joint Bone Spine 2019 Feb 6. Epub 2019 Feb 6.

Service de rhumatologie, CHU de Clermont-Ferrand, Hôpital G. Montpied, 63003 Clermont-Ferrand, France; Unité de nutrition humaine, UMR1019 INRA/Université Clermont Auvergne, 63000 Clermont-Ferrand, France. Electronic address:

Statin-associated muscle symptoms (SAMSs) vary considerably in frequency and severity, with a spectrum extending from myalgia with normal creatine kinase (CK) levels or asymptomatic hyperCKemia to potentially life-threatening rhabdomyolysis and necrotizing autoimmune myopathy. Myalgia with CK elevation is the most common presentation. Onset is usually within 1 month after statin initiation or dosage intensification, and the symptoms can be expected to resolve within a few weeks after treatment discontinuation. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.018DOI Listing
February 2019
5 Reads

Increased incidence of spondyloarthropathies in patients with Takayasu arteritis: a systematic clinical survey.

Joint Bone Spine 2019 Feb 6. Epub 2019 Feb 6.

Division of Rheumatology, Department of Internal Medicine, Gazi University Faculty of Medicine, Ankara, Turkey.

Objectives: Takayasu arteritis and Spondyloarthritis are two distinct inflammatory diseases that affect the same age periods. Increasing number of reports on co-incident Takayasu arteritis-spondyloarthritis cases in literature raised the hypotheses about their association. The purpose of this study is to evaluate the incidence of spondyloarthropathy spectrum diseases in Takayasu arteritis patients. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.020DOI Listing
February 2019
2 Reads
2.901 Impact Factor

Has Paget's bone disease become rare?

Joint Bone Spine 2019 Feb 4. Epub 2019 Feb 4.

Pôle appareil locomoteur, service de rhumatologie, hôpitaux universitaires Saint-Louis Lariboisière Fernand-Widal, AP-HP, université Paris Diderot et Inserm UMR132 BIOSCAR, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.jbspin.2019.01.015DOI Listing
February 2019

Cryoglobulinemia: An update in 2019.

Joint Bone Spine 2019 Feb 4. Epub 2019 Feb 4.

Sorbonne universités, UPMC Université Paris 06, Inserm, UMR S 959, immunology immunopathology immunotherapy (I3), 75005, Paris, France; Biotherapy (CIC-BTi) and inflammation-immunopathology-biotherapy department (DHU i2B), hôpital Pitié-Salpêtrière, AP-HP, 75651, Paris, France; AP-HP, groupe hospitalier Pitié-Salpêtrière, department of internal medicine and clinical immunology, centre national de référence maladies autoinflammatoires et amylose inflammatoire, centre national de références maladies autoimmunes systémiques rares, 75013, Paris, France. Electronic address:

Cryoglobulinemia is defined as the persistent presence in serum of abnormal immunoglobulins (Igs) that precipitate at low temperatures and dissolve again upon warming. Cryoglobulins may be composed only of a monoclonal Ig (simple type I cryoglobulinemia), of a monoclonal Ig bound to the constant domain of polyclonal Ig heavy chains (mixed type II cryoglobulinemia), or only of polyclonal Igs (mixed type III cryoglobulinemia). The manifestations of type I cryoglobulinemia are often related to intravascular obstruction, whereas those seen in the mixed cryoglobulinemias often originate in true immune complex-mediated vasculitis. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.016DOI Listing
February 2019
16 Reads

Added value of [F]fluorodeoxyglucose positron emission tomography/computed tomography for the diagnosis of post-operative instrumented spine infection.

Joint Bone Spine 2019 Jan 31. Epub 2019 Jan 31.

Department of infectious and tropical diseases, hôpital Pellegrin, CHU de Bordeaux, 33076 Bordeaux, France; Centre de référence infections ostéo-articulaires complexes du Grand Sud-Ouest (Crioac GSO), 33076 Bordeaux, France; Inserm U1219 Bordeaux population health, ISPED, university of Bordeaux, 33076 Bordeaux, France. Electronic address:

Purpose: Post-operative instrumented spine infection (PISI) is an infrequent complication. Diagnosis of spinal implant infection can be difficult, especially in case of chronic infection.

Methods: This retrospective study attempts to evaluate the diagnostic performance of [F]fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) in PISI. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.009DOI Listing
January 2019

McCune-Albright syndrome and the shepherd crook deformity.

Joint Bone Spine 2019 Jan 31. Epub 2019 Jan 31.

Rheumatology Department, Centro Hospitalar e Universitario de Coimbra EPE, Coimbra, Portugal.

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http://dx.doi.org/10.1016/j.jbspin.2019.01.010DOI Listing
January 2019
8 Reads

Post-traumatic femoral cartilage separation in a child patient.

Joint Bone Spine 2019 Jan 31. Epub 2019 Jan 31.

Department of Radiology, Medical Faculty, Ataturk University, Erzurum, Turkey.

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http://dx.doi.org/10.1016/j.jbspin.2019.01.007DOI Listing
January 2019

Corneal and scleral involvement in inflammatory rheumatic disease: Rheumatologists and ophthalmologists exchanging views.

Joint Bone Spine 2019 Feb 1. Epub 2019 Feb 1.

Inserm UMR 1125, 1, rue de Chablis, 93017 Bobigny, France; Service de rhumatologie, assistance publique-Hôpitaux de Paris (AP-HP), groupe hospitalier Avicenne Jean-Verdier-René-Muret, 125, rue de Stalingrad, 93017 Bobigny, France.

Corneal and scleral disorders related to inflammatory rheumatic diseases vary both in frequency and in severity. Sicca syndrome and its complications are the most common ocular manifestations and, together with episcleritis, can usually be managed by topical treatments. In contrast, the various forms of scleritis and peripheral ulcerative keratitis generally require systemic glucocorticoid therapy and the initiation or intensification of immunosuppressive treatment. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.014DOI Listing
February 2019

Ultrasonographic criteria for the diagnosis of erosive rheumatoid arthritis using osteoarthritic patients as controls compared to validated radiographic criteria.

Joint Bone Spine 2019 Jan 31. Epub 2019 Jan 31.

Department of rheumatology, university hospital of Nancy, 54500 Vandoeuvre-lès-Nancy, France; Inserm, CIC-EC CIE6, university hospital of Nancy, epidemiology and clinical evaluation, 54500 Vandoeuvre-lès-Nancy, France.

Objectives: The aims of this study were to compare characteristics of radiography (RX) and ultrasound (US) erosive lesions in rheumatoid arthritis (RA) and osteoarthritis (OA) patients (prevalence, topography and severity), to determine thresholds for the diagnosis of erosive RA based on US and to evaluate the performance of US and RX to establish a diagnosis of erosive RA differentiated from hand OA.

Methods: Patients fulfilling ACR 1987 and/or ACR/EULAR 2010 criteria for RA or ACR hand OA criteria were prospectively included. A modified Sharp erosion score was assessed by two blinded readers and one adjudicator for discordant cases (number of eroded joints ≤ three). Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.011DOI Listing
January 2019
2 Reads

Strategy for suspected myositis.

Joint Bone Spine 2019 Feb 1. Epub 2019 Feb 1.

Service de rhumatologie, hôpitaux universitaires de Strasbourg, 67098 Strasbourg, France; Centre de référence des maladies autoimmunes rares de l'Est et Sud Ouest, 33000 Bordeaux, France; Fédération de médecine translationnelle de Strasbourg, université de Strasbourg, 67081 Strasbourg, France.

Skeletal muscle inflammation is the feature shared by all forms of myositis. However, the muscle damage ranges in severity from asymptomatic to responsible for severe weakness. In addition, myositis usually occurs as a systemic disease that affects multiple organs. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.013DOI Listing
February 2019
5 Reads

X-linked hypophosphatemia: Management and treatment prospects.

Joint Bone Spine 2019 Jan 31. Epub 2019 Jan 31.

Centre de référence des maladies rares du métabolisme du calcium et du phosphate, filière OSCAR and plateforme d'expertise maladies rares Paris-Sud, hôpital Bicêtre Paris Sud, AP-HP, 94270 Le Kremlin Bicêtre, France; Endocrinologie et diabète de l'enfant, hôpital Bicêtre Paris Sud, AP-HP, 94270 Le Kremlin Bicêtre, France; Inserm U1185 et université Paris Sud Paris-Saclay, Hôpital Bicêtre Paris Sud, 94270 Le Kremlin Bicêtre, France.

X-linked hypophosphatemia (XLH), due to a PHEX gene mutation, is the most common genetic form of rickets and osteomalacia. Manifestations in children consist of rickets, lower-limb bone deformities, bone pain, failure to thrive, dental abscesses, and/or craniostenosis. Adults may present with persistent bone pain, early osteoarthritis, hairline fractures and Looser zones, enthesopathy, and/or periodontitis. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.012DOI Listing
January 2019
2 Reads

Long-bones involvement in generalized crystal-storing histiocytosis.

Joint Bone Spine 2019 Jan 25. Epub 2019 Jan 25.

Sorbonne université, assistance publique Hôpitaux de Paris, service de médecine interne 2, institut e3m, hôpital de la Pitié-Salpêtrière, centre national de référence maladies rares histiocytoses, Paris 75013, France.

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https://linkinghub.elsevier.com/retrieve/pii/S1297319X183020
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http://dx.doi.org/10.1016/j.jbspin.2019.01.006DOI Listing
January 2019
1 Read

Pathogenic effects of anti-citrullinated protein antibodies in rheumatoid arthritis - role for glycosylation.

Joint Bone Spine 2019 Jan 25. Epub 2019 Jan 25.

Service d'immunologie, Pierre-Bénite, hospices civils de Lyon, CHU de Lyon-sud, 165, chemin du Grand Revoyet, 69310 Pierre-Bénite, France; Unité d'immunogénomique et inflammation, EA4130, Hôpital Edouard-Herriot, 5, place d'Arsonval, 69003 Lyon, France; Faculté de médecine Lyon-Est, université de Lyon, 8, avenue Rockefeller, 69008 Lyon, France. Electronic address:

The identification in 1998 of the main antigenic substrate recognized by autoantibodies was a dramatic turning point in our understanding of rheumatoid arthritis (RA) biology. Now, two decades later, antibodies to citrullinated proteins are viewed no longer as mere biomarkers for RA, but also as major pathophysiological factors involved in the development of bone loss and joint pain. These pathogenic effects are ascribable to abnormal autoantibody glycosylation via a pathway involving the Th17T cells. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1297319X193000
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http://dx.doi.org/10.1016/j.jbspin.2019.01.005DOI Listing
January 2019
7 Reads
2.901 Impact Factor

Translocation of dead or alive bacteria from mucosa to joints and epiphyseal bone-marrow: facts and hypotheses.

Joint Bone Spine 2019 Jan 21. Epub 2019 Jan 21.

Rheumatology unit, CHRU de Besançon, and EA4266 (Pathogens and inflammation, EPILAB) université Bourgogne Franche-Comté, boulevard Fleming, 25030 Besançon, France.

The recent demonstration that DNA from several mucosal bacteria, including Prevotella spp, could be found in numerous tissues (mesenteric lymph nodes, spleen, serum, liver, lung, eye and ankle joints), either in HLA-B27 rats with or without arthritis, or control rats without HLA-B27, could be a revolution in our understanding of spondyloarthritis and close disorders, including rheumatoid arthritis. Indeed, similar translocations of dead or alive bacteria or fungi from mucosa to joints, could contribute to the onset and flares of inflammatory rheumatisms. This state of the art article addresses six questions revived by this finding: 1-How does this bacterial DNA or living bacteria traffic from mucosa to joints? 2-Can some mucosal bacteria remain alive in those tissues, including joints? 3-Could bacteria from the gut microbiota ('self-bacteria') protect the host cells from invasion by more pathogenic bacteria (like dog-shepherds protect from wolves)? 4-Does the composition of the joint or bone marrow microbiota depends on local metabolism, which might differ from gut metabolism? 5-Could bacterial antigens from mucosal microbiota be sufficient to trigger trained immunity of presenting cells in joints, or does such phenomenon (with lasting epigenetic changes of presenting cells) require intra-cellular infection of presenting cells or their ancestors? 6-In which subsets of cells could living bacteria preferentially persist for a long period in the joint area? Transient or dormant infections within bone-marrow mesenchymal stem cells leading to trained immunity of some of their daughter cells in joints or enthesis, lasting after clearance or the invader, is an attractive hypothesis to test. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.004DOI Listing
January 2019
11 Reads

Knee psoriatic enthesitis assessed using positron emission tomography (PET) - FNa merged to ultrahigh field magnetic resonance imaging (UHF-MRI).

Joint Bone Spine 2019 Jan 17. Epub 2019 Jan 17.

Aix-Marseille university, CRMBM-CEMEREM, UMR CNRS 7339, 13385 Marseille, France; Department of rheumatology, AP-HM, Aix-Marseille university, 13274 Marseille, France. Electronic address:

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http://dx.doi.org/10.1016/j.jbspin.2019.01.002DOI Listing
January 2019
9 Reads

Cervical myelopathy revealing a unique case of retinoid hyperostosis.

Joint Bone Spine 2019 Jan 17. Epub 2019 Jan 17.

Service de rhumatologie, centre de compétence des maladies osseuses rares, hôpitaux universitaires de Strasbourg, université de Strasbourg, 67000 Strasbourg, France.

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http://dx.doi.org/10.1016/j.jbspin.2018.12.010DOI Listing
January 2019
1 Read

Systemic calprotectin and chronic inflammatory rheumatic diseases.

Joint Bone Spine 2019 Jan 17. Epub 2019 Jan 17.

GREPI, EA 7408, University Grenoble Alpes, 38700 La Tronche, France; Sinnovial SAS, avenue de Kimberley, 38130 Échirolles, France.

Calprotectin is a calcium binding protein produced by neutrophils and monocytes locally at the site of inflammation in order to trigger the innate immunity receptors. This unique characteristic makes it a good proxy for evaluation of local inflammation in chronic inflammatory rheumatic diseases. Complete data suggest, in inflammatory rheumatic diseases, a relevant role of calprotectin in the inflammatory process. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1297319X183034
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http://dx.doi.org/10.1016/j.jbspin.2019.01.003DOI Listing
January 2019
18 Reads

Internet-based self-diagnosis of Lyme disease caused death in a young woman with systemic lupus erythematosus.

Joint Bone Spine 2019 Jan 17. Epub 2019 Jan 17.

Department of Immunology, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, V Uvalu 84, 15006, Prague 5, Czech Republic.

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http://dx.doi.org/10.1016/j.jbspin.2018.12.011DOI Listing
January 2019
3 Reads

Patients' information and perspectives on biosimilars in rheumatology: A French nation-wide survey.

Joint Bone Spine 2019 Jan 16. Epub 2019 Jan 16.

Rheumatology department, hôpital de Hautepierre, hôpitaux universitaire de Strasbourg, 1 avenue Molière, 67098 Strasbourg, France.

Objective: To assess the patients' information about biosimilars and to identify the patients' incentives and deterrents to concur with the use of biosimilars.

Methods: Nation-wide cross-sectional study assessing information and concerns about biosimilars of French patients treated for rheumatic inflammatory diseases, whether they were treated or not by a biological DMARD. The assessment was available online from March to July 2017. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.001DOI Listing
January 2019
4 Reads

Bamboo nodes as evidence of mixed connective tissue disease.

Joint Bone Spine 2018 Dec 28. Epub 2018 Dec 28.

Department of rheumatology, Ramón y Cajal University Hospital, Ctra. Colmenar Viejo, Km 9,100. PC 28034, Madrid. Spain.

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http://dx.doi.org/10.1016/j.jbspin.2018.12.009DOI Listing
December 2018
4 Reads