3,120 results match your criteria Joint Bone Spine [Journal]


Reply to the comment of Sartorelli et al. "Diagnostic approach and novel therapeutic option for cardiac inflammatory disorders".

Joint Bone Spine 2019 Feb 11. Epub 2019 Feb 11.

AP-HP, Service de Rhumatologie, Hôpital Bichat, 75018 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.jbspin.2019.01.026DOI Listing
February 2019

Assessment of major salivary gland size in primary Sjögren's syndrome: comparison between clinical examination and ultrasonography.

Joint Bone Spine 2019 Feb 11. Epub 2019 Feb 11.

Service de rhumatologie, Centre National de Référence des Maladies Auto-immunes Rares de l'Adulte CERAINO, CHU de Brest, Brest, France; UMR1227, Lymphocytes B et Autoimmunité, Université de Brest, Inserm, LabEx IGO, Brest, France.

Objective: Parotidomegaly is a criterion of the EULAR Primary Sjögren Syndrome Disease Activity Index (ESSDAI). The cut-off value was set at 3 cm in length for the parotid gland, 2 cm for the submandibular glands. However, clinical appreciation of salivary glands size remains hazardous. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.025DOI Listing
February 2019

The management of Osteogenesis Imperfecta in Adults: state of the art.

Joint Bone Spine 2019 Feb 8. Epub 2019 Feb 8.

Service de Médecine Physique et de Rééducation, 42270 Saint-Priest-en-Jarez, France.

Osteogenesis imperfecta (OI) is a genetic disease whose clinical phenotype and severity vary considerably. The increased risk of fractures due to bone fragility persists in adulthood, notably after 40 years of age, albeit at a lower level than during growth. Adults with OI require periodic evaluations of the other manifestations of OI including hearing loss, respiratory impairments, ocular and dental abnormalities, and cardiovascular disease. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.02.001DOI Listing
February 2019
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Assessment of the adherence to disease-modifying drugs in patients with chronic inflammatory rheumatic diseases: results of a survey of 1594 patients.

Joint Bone Spine 2019 Feb 6. Epub 2019 Feb 6.

Département Rhumatologie, Hôpital Cochin, 75014 Paris, France; Inserm (U1153), clinical epidemiology and biostatistics, PRES Sorbonne Paris-Cité, 75014 Paris, France.

Objectives: a) to describe the self-reported adherence to disease modifying drugs (DMARDs) (methotrexate and biological DMARDs) among patients with chronic inflammatory rheumatic diseases (CIRDs); b) to assess factors associated with non-adherence.

Methods: An observational, cross-sectional, nationwide study was conducted through the use of an electronic survey, which was released via patient organizations in France to rheumatic patients. The main outcome was the rate of non-adherence to DMARDs, which was evaluated with the following question "Have you ever tried to stop or space out your treatment in contrast to what was planned with your doctor?". Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.023DOI Listing
February 2019

Exploratory study of adalimumab in twelve patients with chronic low back pain associated with Modic I changes.

Joint Bone Spine 2019 Feb 6. Epub 2019 Feb 6.

Department of rheumatology, HFR Fribourg-Cantonal Hospital, 1708 Fribourg, Switzerland.

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http://dx.doi.org/10.1016/j.jbspin.2019.01.024DOI Listing
February 2019

The Risk of Sjogren's Syndrome in the Older adults with Gout: A Medicare Claims Study.

Joint Bone Spine 2019 Feb 6. Epub 2019 Feb 6.

Department of Medicine at the School of Medicine, University of Alabama at Birmingham, 1720 Second Ave. South, Birmingham, 35294-0022 AL, USA.

Objectives: In the absence of previous studies, our objective was to assess whether gout was associated with an increase or decrease in the risk of Sjogren's Syndrome (SS) in older adults, 65 years or older.

Methods: We used the 5% Medicare claims from 2006-2012. A multivariable Cox regression model assessed the association of gout with incident SS adjusting for age, sex, race, Charlson-Romano comorbidity index, and the use of medications for cardiovascular diseases (statins, beta-blockers, diuretics, ACE-inhibitors) and gout (allopurinol, febuxostat). Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.022DOI Listing
February 2019
1 Read

Curative Treatment of Prosthetic Joint Infection in Patients Younger than 80 vs. 80 or Older.

Joint Bone Spine 2019 Feb 5. Epub 2019 Feb 5.

Centre de Référence des Infections Ostéo-Articulaires Complexes, Groupe Hospitalier Diaconesses-Croix Saint-Simon, 125, rue d'Avron, Paris 75020, France; Service de Chirurgie Osseuse et Traumatologique, Groupe Hospitalier Diaconesses-Croix Saint-Simon, 125, rue d'Avron, Paris 75020, France.

Objective: Prosthetic joint infection (PJI) is a serious complication of joint replacement surgery. The major pharmacological and surgical treatments required by PJI increase the risk of peri-operative complications in elderly patients. The increase in life expectancy combined with procedural advances make these treatments possible even in the oldest patients. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.017DOI Listing
February 2019

Bortezomib Improved the Joint Manifestations of Rheumatoid Arthritis in Three Patients.

Joint Bone Spine 2019 Feb 5. Epub 2019 Feb 5.

Service de rhumatologie, centre hospitalier Jean Rougié Cahors 46000, France.

The proteasome inhibitor bortezomib has been proven effective in the treatment of multiple myeloma. We report on 3 patients with rheumatoid arthritis and multiple myeloma in whom bortezomib therapy was associated with improvements in the joint manifestations. The contribution to this effect of the concomitant glucocorticoid therapy is discussed. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1297319X193001
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http://dx.doi.org/10.1016/j.jbspin.2019.01.019DOI Listing
February 2019
2 Reads

Statins, myalgia, and rhabdomyolysis.

Authors:
Anne Tournadre

Joint Bone Spine 2019 Feb 5. Epub 2019 Feb 5.

Service de rhumatologie, CHU Clermont-Ferrand, Hôpital G Montpied, 63003 Clermont-Ferrand, France; Unité de Nutrition Humaine, UMR1019 INRA/Université Clermont Auvergne, 63000 Clermont-Ferrand, France. Electronic address:

Statin-associated muscle symptoms (SAMSs) vary considerably in frequency and severity, with a spectrum extending from myalgia with normal creatine kinase (CK) levels or asymptomatic hyperCKemia to potentially life-threatening rhabdomyolysis and necrotizing autoimmune myopathy. Myalgia with CK elevation is the most common presentation. Onset is usually within 1 month after statin initiation or dosage intensification, and the symptoms can be expected to resolve within a few weeks after treatment discontinuation. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.018DOI Listing
February 2019

Increased incidence of spondyloarthropathies in patients with Takayasu arteritis: a systematic clinical survey.

Joint Bone Spine 2019 Feb 5. Epub 2019 Feb 5.

Division of Rheumatology, Department of Internal Medicine, Gazi University Faculty of Medicine, Ankara, Turkey.

Objectives: Takayasu arteritis and Spondyloarthritis are two distinct inflammatory diseases that affect the same age periods. Increasing number of reports on co-incident Takayasu arteritis-Spondyloarthritis cases in literature raised the hypotheses about their association. The purpose of this study is to evaluate the incidence of Spondyloarthropathy spectrum diseases in Takayasu arteritis patients. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.020DOI Listing
February 2019
1 Read
2.901 Impact Factor

Has Paget's Bone Disease Become Rare?

Joint Bone Spine 2019 Feb 4. Epub 2019 Feb 4.

Pôle appareil locomoteur, service de rhumatologie, Hôpitaux Universitaires Saint-Louis Lariboisière Fernand Widal, AP-HP, Université Paris Diderot et Inserm UMR132 BIOSCAR, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.jbspin.2019.01.015DOI Listing
February 2019

Cryoglobulinemia: an update in 2019.

Joint Bone Spine 2019 Feb 4. Epub 2019 Feb 4.

Sorbonne Universités, UPMC Univ Paris 06, INSERM, UMR S 959, Immunology Immunopathology Immunotherapy (I3), F-75005, Paris, France; Biotherapy (CIC-BTi) and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), Hôpital Pitié-Salpêtrière, AP-HP, F-75651, Paris, France; AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Department of Internal Medicine and Clinical Immunology, Centre national de références Maladies Autoimmunes et systémiques rares et Maladies Autoinflammatoires rares, F-75013, Paris, France. Electronic address:

Cryoglobulinemia is defined as the persistent presence in serum of abnormal immunoglobulins (Igs) that precipitate at low temperatures and dissolve again upon warming. Cryoglobulins may be composed only of a monoclonal Ig (simple type I cryoglobulinemia), of a monoclonal Ig bound to the constant domain of polyclonal Ig heavy chains (mixed type II cryoglobulinemia), or only of polyclonal Igs (mixed type III cryoglobulinemia). The manifestations of type I cryoglobulinemia are often related to intravascular obstruction, whereas those seen in the mixed cryoglobulinemias often originate in true immune complex-mediated vasculitis. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.016DOI Listing
February 2019
2 Reads

Added value of [18F]fluorodeoxyglucose positron emission tomography/computed tomography for the diagnosis of post-operative instrumented spine infection.

Joint Bone Spine 2019 Jan 31. Epub 2019 Jan 31.

Department of Infectious and Tropical Diseases, Hôpital Pellegrin, CHU de Bordeaux, 33076 Bordeaux, France; Centre de Référence Infections Ostéo-Articulaires Complexes du Grand Sud-Ouest (Crioac GSO), 33076 Bordeaux, France; INSERM U1219 Bordeaux Population Health, ISPED, University of Bordeaux, 33076 Bordeaux, France. Electronic address:

Purpose: Post-operative instrumented spine infection (PISI) is an infrequent complication. Diagnosis of spinal implant infection can be difficult, especially in case of chronic infection.

Methods: This retrospective study attempts to evaluate the diagnostic performance of [18F]fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) in PISI. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.009DOI Listing
January 2019

McCune-Albright Syndrome and the shepherd crook deformity.

Joint Bone Spine 2019 Jan 31. Epub 2019 Jan 31.

Rheumatology Department, Centro Hospitalar e Universitario de Coimbra EPE, Coimbra, Portugal.

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http://dx.doi.org/10.1016/j.jbspin.2019.01.010DOI Listing
January 2019

Post-Traumatic Femoral Cartilage Separation in a Child Patient.

Joint Bone Spine 2019 Jan 31. Epub 2019 Jan 31.

Department of Radiology, Medical Faculty, Ataturk University, Erzurum, Turkey.

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http://dx.doi.org/10.1016/j.jbspin.2019.01.007DOI Listing
January 2019

Corneal and Scleral Involvement in Inflammatory Joint Disease: Rheumatologists and Ophthalmologists Exchanging Views.

Joint Bone Spine 2019 Jan 31. Epub 2019 Jan 31.

Inserm UMR 1125, 1, rue de Chablis, 93017 Bobigny, France; Service de rhumatologie, Assistance publique-Hôpitaux de Paris (AP-HP), groupe hospitalier Avicenne - Jean-Verdier-René-Muret, 125, rue de Stalingrad, 93017 Bobigny, France.

Corneal and scleral disorders related to inflammatory rheumatic diseases vary both in frequency and in severity. Sicca syndrome and its complications are the most common ocular manifestations and, together with episcleritis, can usually be managed by topical treatments. In contrast, the various forms of scleritis and peripheral ulcerative keratitis generally require systemic glucocorticoid therapy and the initiation or intensification of immunosuppressive treatment. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.014DOI Listing
January 2019

Ultrasonographic criteria for the diagnosis of erosive rheumatoid arthritis using osteoarthritic patients as controls compared to validated radiographic criteria.

Joint Bone Spine 2019 Jan 31. Epub 2019 Jan 31.

Department of Rheumatology, University Hospital of Nancy, 54500 Vandoeuvre-lès-Nancy, France; INSERM, CIC-EC CIE6, University Hospital of Nancy, Epidemiology and Clinical Evaluation, 54500 Vandoeuvre-lès-Nancy, France.

Objectives: The aims of this study were to compare characteristics of radiography (RX) and ultrasound (US) erosive lesions in rheumatoid arthritis (RA) and osteoarthritis (OA) patients (prevalence, topography and severity), to determine thresholds for the diagnosis of erosive RA based on US and to evaluate the performance of US and RX to establish a diagnosis of erosive RA differentiated from hand OA.

Methods: Patients fulfilling ACR 1987 and/or ACR/EULAR 2010 criteria for RA or ACR hand OA criteria were prospectively included. A modified Sharp erosion score was assessed by two blinded readers and one adjudicator for discordant cases (number of eroded joints ≤ three). Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.011DOI Listing
January 2019
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Strategy for Suspected Myositis.

Joint Bone Spine 2019 Jan 31. Epub 2019 Jan 31.

Service de rhumatologie, Hôpitaux Universitaires de Strasbourg, 67098 Strasbourg, France; Centre de Référence des Maladies Autoimmunes Rares de l'Est & Sud Ouest, 33000 Bordeaux, France; Fédération de Médecine Translationnelle de Strasbourg, Université de Strasbourg, 67081 Strasbourg, France.

Skeletal muscle inflammation is the feature shared by all forms of myositis. However, the muscle damage ranges in severity from asymptomatic to responsible for severe weakness. In addition, myositis usually occurs as a systemic disease that affects multiple organs. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.013DOI Listing
January 2019
1 Read

X-Linked Hypophosphatemia: Management and Treatment Prospects.

Joint Bone Spine 2019 Jan 31. Epub 2019 Jan 31.

Centre de référence des maladies rares du métabolisme du calcium et du phosphate, filière OSCAR and Plateforme d'Expertise Maladies Rares Paris-Sud, Hôpital Bicêtre Paris Sud, APHP, 94270 Le Kremlin Bicêtre, France; Endocrinologie et diabète de l'enfant, Hôpital Bicêtre Paris Sud, APHP, 94270 Le Kremlin Bicêtre, France; INSERM U1185 et université Paris Sud Paris-Saclay, Hôpital Bicêtre Paris Sud, 94270 Le Kremlin Bicêtre, France.

X-linked hypophosphatemia (XLH), due to a PHEX gene mutation, is the most common genetic form of rickets and osteomalacia. Manifestations in children consist of rickets, lower-limb bone deformities, bone pain, failure to thrive, dental abscesses, and/or craniostenosis. Adults may present with persistent bone pain, early osteoarthritis, hairline fractures and Looser zones, enthesopathy, and/or periodontitis. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.012DOI Listing
January 2019
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Long-bones involvement in generalized crystal-storing histiocytosis.

Joint Bone Spine 2019 Jan 24. Epub 2019 Jan 24.

Sorbonne Université, Assistance Publique Hôpitaux de Paris, Service de Médecine Interne 2, Institut e3m, Hôpital de la Pitié-Salpêtrière, Centre National de Référence Maladies Rares Histiocytoses, Paris 75013, France.

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http://dx.doi.org/10.1016/j.jbspin.2019.01.006DOI Listing
January 2019

Pathogenic Effects of Anti-Citrullinated Peptide Antibodies in Rheumatoid Arthritis - Role for Glycosylation.

Joint Bone Spine 2019 Jan 24. Epub 2019 Jan 24.

Service d'Immunologie, Pierre-Bénite, Hospices Civils de Lyon, CHU Lyon-sud, 165, chemin du Grand Revoyet, 69310 Pierre-Bénite, France; Unité d'Immunogénomique & Inflammation, EA4130, Hôpital Edouard Herriot, 5 place d'Arsonval, 69003 Lyon, France; Faculté de médecine Lyon-Est, Université de Lyon, 8 avenue Rockefeller, 69008 Lyon, France. Electronic address:

The identification in 1998 of the main antigenic substrate recognized by autoantibodies was a dramatic turning point in our understanding of rheumatoid arthritis (RA) biology. Now, two decades later, antibodies to citrullinated peptides are viewed no longer as mere biomarkers for RA, but also as major pathophysiological factors involved in the development of bone loss and joint pain. These pathogenic effects are ascribable to abnormal autoantibody glycosylation via a pathway involving the Th17 T cells. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1297319X193000
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http://dx.doi.org/10.1016/j.jbspin.2019.01.005DOI Listing
January 2019
6 Reads
2.901 Impact Factor

Translocation of dead or alive bacteria from mucosa to joints and epiphyseal bone-marrow: facts and hypotheses.

Joint Bone Spine 2019 Jan 21. Epub 2019 Jan 21.

Rheumatology Unit, CHRU de Besançon, and EA4266 (Pathogens and inflammation, EPILAB) Université Bourgogne Franche-Comté. Boulevard Fleming, 25030 Besançon, France.

The recent demonstration that DNA from several mucosal bacteria, including Prevotella spp, could be found in numerous tissues (mesenteric lymph nodes, spleen, serum, liver, lung, eye and ankle joints), either in HLA-B27 rats with or without arthritis, or control rats without HLA-B27, could be a revolution in our understanding of spondyloarthritis and close disorders, including rheumatoid arthritis. Indeed, similar translocations of dead or alive bacteria or fungi from mucosa to joints, could contribute to the onset and flares of inflammatory rheumatisms. This state of the art article addresses six questions revived by this finding: 1-How does this bacterial DNA or living bacteria traffic from mucosa to joints? 2-Can some mucosal bacteria remain alive in those tissues, including joints? 3-Could bacteria from the gut microbiota ('self-bacteria') protect the host cells from invasion by more pathogenic bacteria (like dog-shepherds protect from wolves)? 4-Does the composition of the joint or bone marrow microbiota depends on local metabolism, which might differ from gut metabolism? 5-Could bacterial antigens from mucosal microbiota be sufficient to trigger trained immunity of presenting cells in joints, or does such phenomenon (with lasting epigenetic changes of presenting cells) require intra-cellular infection of presenting cells or their ancestors? 6-In which subsets of cells could living bacteria preferentially persist for a long period in the joint area? Transient or dormant infections within bone-marrow mesenchymal stem cells leading to trained immunity of some of their daughter cells in joints or enthesis, lasting after clearance or the invader, is an attractive hypothesis to test. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.004DOI Listing
January 2019
5 Reads

Knee psoriatic enthesitis assessed using Positron Emission Tomography (PET)- FNa merged to ultrahigh field magnetic resonance imaging (UHF-MRI).

Joint Bone Spine 2019 Jan 17. Epub 2019 Jan 17.

Aix-Marseille University, CRMBM-CEMEREM, UMR CNRS 7339, 13385 Marseille, France; Department of Rheumatology, AP-HM, Aix-Marseille University, 13274 Marseille, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S1297319X193000
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http://dx.doi.org/10.1016/j.jbspin.2019.01.002DOI Listing
January 2019
3 Reads

Cervical myelopathy revealing a unique case of Retinoid Hyperostosis.

Joint Bone Spine 2019 Jan 17. Epub 2019 Jan 17.

Service de rhumatologie, Centre de Compétence des Maladies Osseuses Rares, Hôpitaux Universitaires de Strasbourg, Université de Strasbourg, 67000 Strasbourg, France.

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http://dx.doi.org/10.1016/j.jbspin.2018.12.010DOI Listing
January 2019

Systemic calprotectin and chronic inflammatory rheumatic diseases.

Joint Bone Spine 2019 Jan 17. Epub 2019 Jan 17.

GREPI, EA 7408, University Grenoble Alpes, 38700 La Tronche, France; Sinnovial SAS, Avenue de Kimberley, 38130 Échirolles, France.

Calprotectin is a calcium binding protein produced by neutrophils and monocytes locally at the site of inflammation in order to trigger the innate immunity receptors. This unique characteristic makes it a good proxy for evaluation of local inflammation in chronic inflammatory rheumatic diseases. Complete data suggest, in inflammatory rheumatic diseases, a relevant role of calprotectin in the inflammatory process. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1297319X183034
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http://dx.doi.org/10.1016/j.jbspin.2019.01.003DOI Listing
January 2019
10 Reads

Internet-based self-diagnosis of Lyme disease caused death in a young woman with systemic lupus erythematosus.

Joint Bone Spine 2019 Jan 17. Epub 2019 Jan 17.

Department of Immunology, 2ndFaculty of Medicine, Charles University in Prague and Motol University Hospital, V Uvalu 84, 150 06, Prague 5, Czech Republic.

In the majority of cases, Lyme disease responds well to antibiotic treatment. Nevertheless, some patients may suffer from chronic nonspecific symptoms such as musculoskeletal pain and fatigue, termed as a post-treatment Lyme disease syndrome (PTLDS). Proper understanding and management of PTLDS may prevent from the incorrect diagnosis of patients with autoimmune, neuromuscular or other somatic disorders, where identical symptoms are equally prevalent. Read More

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http://dx.doi.org/10.1016/j.jbspin.2018.12.011DOI Listing
January 2019
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Patients' information and perspectives on biosimilars in rheumatology: a French nation-wide survey.

Joint Bone Spine 2019 Jan 16. Epub 2019 Jan 16.

Rheumatology department, Hôpital de Hautepierre, Hôpitaux Universitaire de Strasbourg, 1 avenue Molière, 67 098 Strasbourg, France.

Objective: To assess the patients' information about biosimilars and to identify the patients' incentives and deterrents to concur with the use of biosimilars.

Methods: Nation-wide cross-sectional study assessing information and concerns about biosimilars of French patients treated for rheumatic inflammatory diseases, whether they were treated or not by a biological DMARD. The assessment was available online from March to July 2017. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.001DOI Listing
January 2019

Bamboo nodes as evidence of mixed connective tissue disease.

Joint Bone Spine 2018 Dec 28. Epub 2018 Dec 28.

Department of rheumatology, Ramón y Cajal University Hospital, Ctra. Colmenar Viejo, Km 9,100. PC 28034, Madrid. Spain.

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http://dx.doi.org/10.1016/j.jbspin.2018.12.009DOI Listing
December 2018
2 Reads

Gene-environment interactions in Paget's disease of bone.

Joint Bone Spine 2018 Dec 27. Epub 2018 Dec 27.

CHU de Québec-Université Laval Research Centre, Québec (Québec), G1V 4G2, Canada; Department of Medicine, Université Laval, Québec (Québec), G1V 0A6, Canada; Department of Rheumatology, CHU de Québec-Université Laval, Québec (Québec), G1V 4G2, Canada. Electronic address:

Objectives: This study explored the role of outdoor and indoor air pollutants in Paget's disease of bone (PDB).

Methods: We performed a survey in 140 French-Canadian patients with PDB, including 39 carriers ofp.Pro392Leu mutation (SQSTM1 gene) and 113 healthy not mutated controls. Read More

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http://dx.doi.org/10.1016/j.jbspin.2018.12.007DOI Listing
December 2018
7 Reads

Can patients on methotrexate receive live vaccines?

Joint Bone Spine 2018 Dec 27. Epub 2018 Dec 27.

Service des maladies infectieuses et tropicales, hôpital Pitié-Salpêtrière, assistance publique-Hôpitaux de Paris, 47-83, boulevard de l'hôpital, 75013 Paris, France; Sorbonne Université, Inserm U1135, 75013 Paris, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S1297319X183044
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http://dx.doi.org/10.1016/j.jbspin.2018.12.008DOI Listing
December 2018
9 Reads

Repeated switches between reference product etanercept and biosimilar do not affect disease activity or retention rate of etanercept over 24 months - a cohort study with historical controls.

Joint Bone Spine 2018 Dec 22. Epub 2018 Dec 22.

Center for Clinical Research (CKF) Dalarna, Uppsala University, Falun, Sweden; Department of Rheumatology, Falun General Hospital, Falun, Sweden.

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http://dx.doi.org/10.1016/j.jbspin.2018.12.003DOI Listing
December 2018

Why Is Systemic Lupus Erythematosus More Common in Women?

Joint Bone Spine 2018 Dec 22. Epub 2018 Dec 22.

Centre de Physiopathologie de Toulouse Purpan (CPTP), 31024 Toulouse Cedex 3, France; Université de Toulouse, 31300 Toulouse, France; INSERM, CNRS, UPS, 31300 Toulouse, France. Electronic address:

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http://dx.doi.org/10.1016/j.jbspin.2018.12.004DOI Listing
December 2018
1 Read

The Phenotypic Approach to Osteoarthritis: A Look at Metabolic Syndrome-Associated Osteoarthritis.

Joint Bone Spine 2018 Dec 22. Epub 2018 Dec 22.

Service de Rhumatologie, Hôpital Saint-Antoine, Assistance Publique - Hôpitaux de 75012, Paris, France; Sorbonne Université, Paris, France; Centre de Recherche Saint-Antoine, INSERM UMR_S 938, Paris, France. Electronic address:

Metabolic syndrome-associated osteoarthritis (Met-OA) is a clinical phenotype defined by the role of obesity and metabolic syndrome as risk factors and by chronic low-grade inflammation. Obesity is an established risk factor for osteoarthritis not only at the knee, but also at the hands. Metabolic syndrome is also a risk factor for osteoarthritis, and a cumulative effect of the various syndrome components combines with an independent effect of each individual component (diabetes, dyslipidemia, and/or hypertension). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1297319X183044
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http://dx.doi.org/10.1016/j.jbspin.2018.12.005DOI Listing
December 2018
9 Reads

Trained Immunity and Autoimmune Disease: Did Eve Sin before Adam?

Joint Bone Spine 2018 Dec 22. Epub 2018 Dec 22.

Department of Rheumatology, Reference Center for Rare Autoimmune Diseases, Division of Internal Medicine, Hautepierre Hospital, University Hospital of Strasbourg, France.

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https://linkinghub.elsevier.com/retrieve/pii/S1297319X183044
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http://dx.doi.org/10.1016/j.jbspin.2018.12.006DOI Listing
December 2018
1 Read

"Disease knowledge index" and perspectives on reproductive issues: A nationwide study on 398 women with autoimmune rheumatic diseases.

Joint Bone Spine 2018 Dec 21. Epub 2018 Dec 21.

Department of Clinical and Experimental Sciences, University of Brescia, Viale Europa 11, 25123 Brescia, Italy; Rheumatology and Clinical Immunology Unit, ASST Spedali Civili, Piazzale Spedali Civili, 1, 25123 Brescia, Italy.

Objective: The reproductive choices of women affected by rheumatic diseases (RD) can be influenced by several factors, including the quality of physician-patient communication. We conducted a survey on reproductive issues aiming at exploring the unmet needs of women with RD during childbearing age.

Methods: We administered 65 multiple-choice and 12 open-answer questions about pregnancy counselling, contraception, use of drugs during pregnancy and other women reproductive issues to 477 consecutive women with RD aged 18-55 years followed-up in 24 rheumatology centres in Italy. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1297319X183025
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http://dx.doi.org/10.1016/j.jbspin.2018.12.002DOI Listing
December 2018
8 Reads

Pristane-induced arthritis in dark Agouti rat is a relevant model for mimicking vascular dysfunction and lipid paradox in rheumatoid arthritis.

Joint Bone Spine 2018 Dec 19. Epub 2018 Dec 19.

PEPITE EA4267, FHU INCREASE, Université Bourgogne Franche-Comté, 25000 Besançon, France.

Objectives: To understand the pathophysiology of cardiovascular (CV) dysfunction in rheumatoid arthritis (RA) is crucial, but limited by the paucity of animal models able to mimic CV impairments. We wanted to determine if the rat model of Pristane-Induced Arthritis (PIA) reproduced cardiometabolic impairments of RA.

Methods: Dark Agouti rats received an injection of pristane or saline (controls) at day 0. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1297319X183026
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http://dx.doi.org/10.1016/j.jbspin.2018.12.001DOI Listing
December 2018
8 Reads

Obstetrical morbidity related to anti-SSA antibodies: Data from a French monocentric retrospective study.

Joint Bone Spine 2018 Dec 5. Epub 2018 Dec 5.

Sorbonne universités, 75006 Paris, France; Service de médecine interne-DHU i2B, hôpital Saint-Antoine, AP-HP, 75012, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.jbspin.2018.11.005DOI Listing
December 2018
4 Reads

New concepts to reduce glucocorticoid toxicity.

Joint Bone Spine 2018 Dec 5. Epub 2018 Dec 5.

Schlosspark-Klinik Charité University Medicine Berlin, Heubnerweg, 2, 14059 Berlin, Germany.

70 years after their first use, low-dose glucocorticoids are a common part of pharmacological rheumatoid arthritis treatment. This is due to their well-proven capacities in symptom severity and disease activity reduction, in particular when combined with a disease-modifying anti-rheumatic drug, such as methotrexate. Nevertheless, glucocorticoid administration, in long-term especially, is also seen critically because of its potential adverse conditions. Read More

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http://dx.doi.org/10.1016/j.jbspin.2018.11.006DOI Listing
December 2018
2 Reads

Lamin A/C gene (LMNA) mutation associated with laminopathy: A rare cause of idiopathic acro-osteolysis.

Joint Bone Spine 2018 Dec 6. Epub 2018 Dec 6.

CHU de Caen, department of rheumatology, avenue de la Côte de Nacre, Caen, 14000, France; Université Caen Normandie, medical School, Caen, 14000, France.

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http://dx.doi.org/10.1016/j.jbspin.2018.11.008DOI Listing
December 2018

The Tuck sign-proliferative extensor tenosynovitis of the wrist.

Joint Bone Spine 2018 Dec 6. Epub 2018 Dec 6.

Rheumatology Department, Norfolk and Norwich University Hospital, Colney lane, Norwich, NR4 7UY, UK.

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http://dx.doi.org/10.1016/j.jbspin.2018.11.007DOI Listing
December 2018
3 Reads
2.901 Impact Factor

New data in causes of autoinflammatory diseases.

Joint Bone Spine 2018 Nov 22. Epub 2018 Nov 22.

Centre national de référence des maladies auto-inflammatoires et de l'amylose inflammatoire (CEREMAIA), 94270 Le Kremlin-Bicêtre, France; Cellules souches, plasticité cellulaire, médecine régénératrice et immunothérapies, Inserm, Université de Montpellier, 34090 Montpellier, France; Département de génétique médicale, maladies rares et médecine personnalisée, CHU de Montpellier, 34295 Montpellier, France.

The spectrum of factors known to mediate autoinflammation has broadened recently to include not only interleukin-1 (IL-1) and interferon, but also abnormalities that impair NF-κB pathway negative regulation. The NF-κB pathway is activated upon contact of a ligand with tumor necrosis factor receptor 1 (TNFR1) and plays a pivotal role in triggering the inflammatory process by producing major cytokines such as IL-1, IL-6, and TNF. Negative regulation of the NF-κB pathway, which is essential to stop the inflammatory process, depends on the level of ubiquitination of the proteins associated with TNFR1 and of other intermediate compounds. Read More

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http://dx.doi.org/10.1016/j.jbspin.2018.11.003DOI Listing
November 2018
15 Reads

Singular case of osteolytic lesions revealing transformation of myeloproliferative syndrome to acute leukemia.

Joint Bone Spine 2018 Nov 22. Epub 2018 Nov 22.

Service de rhumatologie, CHU d'Angers, 4, rue Larrey, 49933 Angers cedex 9, France; Groupe d'Eudes Remodelage Osseux et bioMatériaux LHEA UPRES EA 4658, CHU d'Angers, 4, rue Larrey, 49933 Angers cedex 9, France. Electronic address:

Hematological malignancies can cause bone lesions, of which the most common are the punched-out foci of osteolysis seen in multiple myeloma. However, osteosclerotic lesions are more common in myeloproliferative disorders. We report the unusual case of a patient with myeloproliferative syndrome in whom the development of osteolytic lesions revealed transformation to acute leukemia. Read More

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http://dx.doi.org/10.1016/j.jbspin.2018.11.004DOI Listing
November 2018
13 Reads

Dietary fibers in osteoarthritis: What are the evidences?

Joint Bone Spine 2018 Nov 22. Epub 2018 Nov 22.

Sorbonne université, 75012 Paris, France; INSERM UMRS_938, CRSA, 75012 Paris, France; Département hospitalo-universitaire "inflammation-immunopathologie-biotherapie" (DHU i2B), 75012 Paris, France; Service de rhumatologie, hôpital Saint-Antoine, assistance publique - hôpitaux de Paris (AP-HP), 75012 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.jbspin.2018.10.010DOI Listing
November 2018
13 Reads

Urate and osteoarthritis: Evidence for a reciprocal relationship.

Joint Bone Spine 2018 Nov 22. Epub 2018 Nov 22.

Rheumatology Section, Department of Medicine, New York Harbor Health Care System, New York Campus, US Department of Veterans Affairs, New York, NY, 10003, USA; Crystal Diseases Study Group, Division of Rheumatology, Department of Medicine, New York University School of Medicine/NYU Langone Health, New York, NY, 10016, USA; NYU Langone Orthopedic Hospital, 301 East 17th Street, Suite 1410, New York, NY 10003, USA. Electronic address:

Hyperuricemia is a common condition, and in a subset of patients leads to gout, the most common inflammatory arthritis. Osteoarthritis is the most common form of arthritis overall, and gout and osteoarthritis frequently coexist in the same patient. However, the relationship between the two remains poorly defined. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1297319X183020
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http://dx.doi.org/10.1016/j.jbspin.2018.11.002DOI Listing
November 2018
7 Reads

The relapsing polychondritis damage index (RPDAM): Development of a disease-specific damage score for relapsing polychondritis.

Joint Bone Spine 2018 Nov 15. Epub 2018 Nov 15.

Service de rhumatologie, centre de référence des maladies autoimmunes systemiques rares Est Sud-Ouest (RESO), hôpital de Hautepierre, 1, avenue Molière BP 83049, 67098 Strasbourg cedex, France; Inserm UMR-S1109, 67098 Strasbourg cedex, France. Electronic address:

Objectives: Relapsing polychondritis is a rare, multi-systemic and inflammatory condition of unknown origin. We currently lack a core set of measures to assess and follow damage in patients suffering from this condition. Our primary aim was to derive a disease-specific damage measuring tool for relapsing polychondritis, the Relapsing Polychondritis Damage Index (RPDAM). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1297319X183030
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http://dx.doi.org/10.1016/j.jbspin.2018.11.001DOI Listing
November 2018
17 Reads
2.901 Impact Factor

Biosimilars: complements and comments on the recent statement of the SFR and CRI. Comment on: "Biosimilars: An opportunity. Position statement of the French Rheumatology Society (SFR) and Inflammatory Rheumatic Disease Club (CRI)." Schaeverbeke et al. Joint Bone Spine 2018;95:399-402.

Joint Bone Spine 2018 Oct 27. Epub 2018 Oct 27.

Law and health economics department, faculty of pharmacy, Paris Descartes university, Sorbonne Paris Cité, 4, avenue de l'Observatoire, 75006 Paris, France; Health law institute (Inserm UMR S1145), Paris Descartes university, Sorbonne Paris Cité, 45, rue des Saints-Pères, 75006 Paris, France; Pharmacy department, general agency of equipments and health products (AGEPS), 7, rue du Fer à Moulin, 75005 Paris, France.

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https://linkinghub.elsevier.com/retrieve/pii/S1297319X183018
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http://dx.doi.org/10.1016/j.jbspin.2018.10.009DOI Listing
October 2018
6 Reads

Implication of nurse intervention on engagement with urate-lowering drugs: A qualitative study of participants in a RCT of nurse led care.

Joint Bone Spine 2018 Oct 27. Epub 2018 Oct 27.

Academic rheumatology, faculty of medicine & health sciences, school of medicine, university of Nottingham, Nottingham, UK; Nottingham NIHR biomedical research centre, Nottingham, UK. Electronic address:

Objectives: To explore patient perception of the role of a nurse-led complex package of care in facilitating engagement with urate-lowering therapies (ULTs) in the management of gout.

Methods: Thirty people who had participated in a randomised controlled trial investigating the effect of a nurse-led complex package of care for gout, were purposively sampled and interviewed between 18-26 months after the end of the trial. Interviews were recorded, transcribed and analysed using a modified grounded-theory approach. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1297319X183016
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http://dx.doi.org/10.1016/j.jbspin.2018.10.008DOI Listing
October 2018
8 Reads

Remission and stringent treatment goals in psoriatic arthritis: Doctors' opinion is not enough.

Authors:
Rubén Queiro

Joint Bone Spine 2018 Jul 3. Epub 2018 Jul 3.

Rheumatology Division, Hospital Universitario Central de Asturias (HUCA), Avda. de Roma s/n, 33011 Oviedo, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jbspin.2018.06.003DOI Listing
July 2018
5 Reads