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Pain Med 2019 Feb 18. Epub 2019 Feb 18.

Center for Pain Medicine, Erasmus MC-University Medical Center, Rotterdam, the Netherlands.

Objective: Although complex regional pain syndrome (CRPS) of the knee is comparable to CRPS of the ankle/foot at time of diagnosis, no reports are available concerning the course of knee CRPS. Therefore, this study investigated the clinical course in terms of the symptoms and signs, health-related quality of life (HR-QoL), and work status of patients diagnosed with CRPS of the knee.

Design: Observational, descriptive study. Read More

Cas Lek Cesk 2019 ;157(8):411-418

Medical and allied health professions are characteristic of an everyday intense contact with patients and clients. However, these interactions also bring about increased danger of psychosocial risks. Psychosocial risks involve job content, its organization and management, as well as its social context. Read More

Niger J Clin Pract 2019 Feb;22(2):167-173

Department of Family Medicine, Dokuz Eylül University, İzmir, Turkey.

Background: Burnout is a psychosocial syndrome, involving feelings of emotional exhaustion, depersonalization, and diminished personal accomplishment at work. Its occurrence is high in healthcare personnel. Job satisfaction is achieved through the feeling of being professionally competent and is an important condition that prevents burnout syndrome. Read More

Disabil Rehabil 2019 Feb 3:1-16. Epub 2019 Feb 3.

b CanChild Centre for Childhood Disability Research and School of Rehabilitation Science , McMaster University , Hamilton , Canada.

Purpose: To identify workplace accommodations that can contribute to obtaining or maintaining employment for adults with autism spectrum disorder in the peer- reviewed literature.

Method: A scoping review of peer-reviewed articles published between January 1987 and March 2018 was performed. Three independent reviewers searched seven databases. Read More

BMJ Open 2019 Jan 28;9(1):e024296. Epub 2019 Jan 28.

Department of Nervous System Diseases, Faculty of Health Sciences, Wroclaw Medical University, Wroclaw, Poland.

Objectives: To assess life satisfaction, job satisfaction, life orientation and the level of professional burnout in a group of professionally active nurses and midwives.

Design: A cross-sectional study.

Setting: This study was conducted between March and October of 2017 during specialisation training at the European Centre for Postgraduate Education in Wroclaw, Poland. Read More

Psychiatry Res 2019 Jan 11;273:312-317. Epub 2019 Jan 11.

Center for Psychiatric Rehabilitation, Departments of Occupational Therapy, Psychological and Brain Sciences, and Psychiatry, Boston University, 940 Commonwealth Ave. West, Boston, MA 02215, USA. Electronic address:

Deciding whether to disclose one's psychiatric disorder to a prospective employer is a complex decision for people with severe mental illness seeking to return to work, with potential advantages and disadvantages. The present study examined the rates, patterns, and correlates of disclosure in 51 participants (74.5% schizophrenia or schizoaffective disorder) receiving high fidelity Individual Placement Support (IPS) who obtained competitive work over a two-year study period. Read More

J Clin Med 2019 Jan 17;8(1). Epub 2019 Jan 17.

Centre for Interdisciplinary Social Research, Phenikaa University, Yen Nghia, Ha Dong, Hanoi 100803, Vietnam.

Protecting the rights of the lesbians, gays, bisexuals, transgender, intersex, and queers (LGBTIQ) population requires, first and foremost, a proper understanding of their sexual orientation and gender identity. This study highlights a severe misunderstanding and lack of knowledge among health professionals in Vietnam with regard to the men who have sex with men (MSM) and transgenders. This study uses (i) a survey based on the convenience sampling method among 150 health workers that covered 61 questions and (ii) 12 in-depth interviews in two metropolitan centres in Vietnam, Hanoi and Ho Chi Minh city. Read More

J Clin Nurs 2019 Jan 17. Epub 2019 Jan 17.

Student Research Committee, School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran.

Aim: To investigate the relation between the circadian rhythm amplitude and stability, and occupational stress with burnout syndrome and job dissatisfaction among shift working nurses.

Background: Irregular shift working nurses are prone to burnout syndrome (BS) and job dissatisfaction (JD). circadian rhythm difference and occupational stress might be effective in causing burnout syndrome and dissatisfaction. Read More

Health Care Manag (Frederick) 2019 Jan/Mar;38(1):3-10

Author Affiliations: Healthcare Administration Program, Lewis College of Business, Marshall University (Mrs Bakhamis); Department of Marketing and International Business, Monmouth University (Dr Paul); and Lewis College of Business, Marshall University (Drs Smith and Coustasse), South Charleston, West Virginia.

The number of registered nurses (RNs) in the United States is roughly 3 times the number of physicians and surgeons, making RNs a critically important component of the US health care system. Registered nurse burnout-the state of emotional exhaustion in which the individual feels overwhelmed by work to the point of feeling fatigued, unable to face the demands of the job, and unable to engage with others-is a real concern, having been reported in many hospitals. The purpose of this research was to examine the causes and consequences of burnout syndrome among RNs in US hospitals and its role in the RN shortage in hospitals. Read More

J Educ Health Promot 2018 27;7:145. Epub 2018 Nov 27.

Department of Paraclinical Sciences, Public Health Unit, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.

Background: Due to exhaustive working climate, health-care professionals (HCPs) are highly exposed to emotional strain and work-related stress that leads to burnout syndrome (BOS).

Aim: We aimed to explore the prevalence of BOS among HCPs and delineate the factors that contribute to developing this emerging threat in HCPs working in Gondar University Hospital (GUH).

Methods: A cross-sectional study was conducted among HCPs using a self-administered validated questionnaire containing sociodemographic and job characteristics, symptoms of burnout using Astudillo and Mendinueta questionnaire, and Maslach Burnout Inventory scale. Read More

Ann Agric Environ Med 2018 Dec 13;25(4):610-615. Epub 2017 Jul 13.

Department for Woman Health, Institute of Rural Health in Lublin, Poland.

Introduction: Metabolic Syndrome is a set of interrelated risk factors for the emergence and progression of cardiovascular disease and diabetes, such as central obesity (abdominal), elevated blood pressure and disorders of carbohydrate and lipid metabolism. Peri- and postmenopausal women are particularly at risk of developing MS, by aging and the loss of protective effect of estrogen on the body, additionally by intellectual work associated with a sedentary lifestyle and job stress. The aim of our study was to analyze the frequency of MS and its criteria in perimenopausal and postmenopausal women doing intellectual work, as well as selected factors on which metabolic syndrome depend. Read More

Am J Med Genet A 2019 Feb 24;179(2):161-176. Epub 2018 Dec 24.

Down Syndrome Program, Division of Medical Genetics, Department of Pediatrics, Massachusetts General Hospital, Boston, Massachusetts.

A realistic assessment of the range of functional abilities found in people with Down syndrome (DS) may assist in counseling expectant parents. This study asked parents from the United States and the Netherlands to assess 11 functional skills of their sons and daughters with DS: walking, eating, speaking, grooming/personal hygiene, reading, writing, preparing meals, working at a job, going on dates, traveling independently, and living independently. We analyzed responses from 2,658 parents who have sons/daughters with DS of all ages. Read More

Medicine (Baltimore) 2018 Dec;97(49):e13364

School of Pharmaceutical Sciences, São Paulo State University, Araraquara.

Research shows an instability in the way workers in the healthcare field live, and a prevalence of an unhealthy lifestyle. Exhaustion, an overload of obligations and responsibilities and dissatisfaction are all factors that may result in both physical and mental disorders. The aim of our study is to analyze the association between individual and occupational aspects of hospital workers and their job satisfaction, burnout syndrome, and depressive symptoms, as well as the relationship between these 3 factors. Read More

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2018 Oct;36(10):728-733

Department of Public Health Management, Tianjin 4th Center Hospital, Tianjin 300140, China.

To investigate the effect of biofeedback therapy on metabolic syndrome (MS) and the effect of different levels of job stress on the outcome. The physicians in tertiary hospitals who were diagnosed with MS from January to December, 2016 were divided into biofeedback group and health education group according to different intervention methods, and moderate group, medium group, and high group according to different levels of job stress. A 6month intervention was implemented from May to October, 2017. Read More

Transfusion 2018 Dec;58 Suppl 3:3056-3064

Division of Clinical Immunology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.

Primary immunodeficiency (PID) diseases result from genetic defects of the immune system that increase a patient's susceptibility to infections. The types of infections that occur in patients with PID diseases are dictated largely by the nature of the immunodeficiency, which can be defined by dysfunction of cellular or humoral defenses. An increasing number of PID diseases, including those with both cellular and humoral defects, have antibody deficiency as a major feature, and as a result can benefit from immunoglobulin replacement therapy. Read More

Int J Environ Res Public Health 2018 12 2;15(12). Epub 2018 Dec 2.

Department of Psychology, Faculty of Psychology, University of Almería, 04120 Almería, Spain.

Health care personnel are considered one of the worker sectors most exposed to heavier workloads and work stress. One of the consequences associated with the exposure to chronic stress is the development of burnout syndrome. Given that evaluating this syndrome requires addressing the context in which they are to be used, the purpose of this work was to analyze the psychometric properties and structure of the Burnout Brief Questionnaire (CBB), and to propose a more suitable version for its application to health professionals, and more specifically nurses. Read More

J Indian Assoc Pediatr Surg 2018 Oct-Dec;23(4):225-227

Department of Pediatric Surgery, All India Institute of Medical Sciences, New Delhi, India.

Chest-drain insertion is considered to be a benign procedure. A 6-year-old girl who is a known case of hyper-IgE/Job's syndrome presented to us following three episodes of fresh bleed following chest-drain insertion for the left lung abscess. The site of bleed was localized to be the ruptured pseudoaneurysm of the anterior segmental branch of the left pulmonary artery. Read More

Hand (N Y) 2018 Nov 12:1558944718810860. Epub 2018 Nov 12.

1 Massachusetts General Hospital, Boston, USA.

Background: This study aims to describe the long-term patient-reported outcomes after surgery for hypothenar hammer syndrome (HTHS) and to identify factors associated with inferior outcomes.

Methods: We retrospectively identified 27 patients who underwent surgical intervention for HTHS from 2002 to 2016. Fifteen patients (56%) completed outcome questionnaires: Quick Disabilities of the Arm, Shoulder, and Hand, Cold Intolerance Symptom Severity (CISS) survey, Patient-Reported Outcomes Measurement Information System Upper Extremity Computer Adaptive Test, and Patient-Reported Outcomes Measurement Information System Pain Interference Computer Adaptive Test. Read More

Brain Nerve 2018 Nov;70(11):1225-1236

Medical Institute of Developmental Disabilities Research, Showa University.

In 2008, we launched a new outpatient clinic and day care service designed exclusively for adults with autism spectrum disorder (ASD). Since then, more than 6000 people visited our facility. We have also launched the Medical Institute for Developmental Disabilities Research (MIDDR) at Showa University, where neuroimaging studies with a 3. Read More

Nat Rev Dis Primers 2018 Nov 8;4(1):43. Epub 2018 Nov 8.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

Multiple sclerosis (MS) is the most common chronic inflammatory, demyelinating and neurodegenerative disease of the central nervous system in young adults. This disorder is a heterogeneous, multifactorial, immune-mediated disease that is influenced by both genetic and environmental factors. In most patients, reversible episodes of neurological dysfunction lasting several days or weeks characterize the initial stages of the disease (that is, clinically isolated syndrome and relapsing-remitting MS). Read More

Rev Lat Am Enfermagem 2018 Oct 25;26:e3056. Epub 2018 Oct 25.

Universidade Estadual de Campinas, Faculdade de Enfermagem, Campinas, SP, Brazil.

Objective: to propose and analyze a theoretical model to measure the effect of nurses' perceptions about the practice environment on safety climate, job satisfaction, intention to stay employed and in the profession, and burnout syndrome.

Method: correlational study with probabilistic sample of 465 nurses. In the theoretical model, the dimensions of the nursing practice environment were considered as independent variables and job satisfaction, safety climate, intention to stay employed and in the profession, and burnout were considered the outcome variables. Read More

Clinics (Sao Paulo) 2018 Oct 18;73:e428. Epub 2018 Oct 18.

Associacao Nacional de Medicina do Trabalho, Vitoria, ES, BR.

Objectives: The function of a medical expert within the scope of the Brazilian social security system consists of medically evaluating the examinee to draw a conclusive opinion on the person's working ability capacity and to characterize the disability for social security and assistance purposes. Forensic decisions inevitably converge on two opposite outcomes: concession or refusal. Rejection is against the interests of the candidates, who can direct their disappointment and dissatisfaction at the professional, exposing the latter to potentially stressful situations. Read More

J Adv Med Educ Prof 2018 Oct;6(4):162-167

Shiraz University of Medical Sciences, Shiraz, Iran.

Introduction: Occupational burnout is a prevalent syndrome among medical students as well as other health professionals. It may be an important factor contributing to professional conducts. The aim of this study was to determine the prevalence of burnout among medical students of Shiraz University of Medical Sciences at clinical level and its relationship with professionalism. Read More

Cancer Radiother 2018 Dec 19;22(8):784-789. Epub 2018 Oct 19.

Département de radiothérapie, centre Henri-Becquerel, 1, rue d'Amiens, 76000 Rouen, France; CNRS, Laboratoire QuantIF, EA4108-Litis, FR UMR 3638, 1, rue d'Amiens, 76000 Rouen, France; Société française des jeunes radiothérapeutes oncologues (SFjRO), centre Antoine-Béclère, 47, rue de la Colonie, 75013 Paris, France.

Purpose: Cancer caregivers are at high risk of burn-out, with potential severe consequences on professionals' health and on patients' care. We have investigated the prevalence of burn-out and its impact in terms of psychological morbidity among French radiation oncologists.

Methods And Materials: An anonymous online questionnaire was advertised in all French senior radiation oncologists and residents, including demographical data, job-related stress factors, drug use, the Maslach Burn-out Inventory (MBI) and the General Health Questionnaire (GHQ-12). Read More

Ann Gen Psychiatry 2018 8;17:43. Epub 2018 Oct 8.

Research and Training Department, Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia.

Introduction: There is a cultural variability around the perception of what causes the syndrome of schizophrenia. As far as the cause of schizophrenia by the general public concerned, people living in western countries focus mainly on biological and social risk factors such as genetic vulnerability, disease of the brain, infection or stressful social conditions or personal weakness, but the predominant views held by people living in non-western countries focus mainly on supernatural and religious factors. Awareness and beliefs about the causes of mental illnesses influence the preferred treatments. Read More

J Am Coll Cardiol 2018 Oct;72(17):2000-2002

Division of Cardiovascular Medicine, UC San Diego Sulpizio Cardiovascular Center, La Jolla, California. Electronic address: https://twitter.com/oribenyehuda.

JAMA 2018 09;320(11):1131-1150

Harvard Medical School, Boston, Massachusetts.

Importance: Burnout is a self-reported job-related syndrome increasingly recognized as a critical factor affecting physicians and their patients. An accurate estimate of burnout prevalence among physicians would have important health policy implications, but the overall prevalence is unknown.

Objective: To characterize the methods used to assess burnout and provide an estimate of the prevalence of physician burnout. Read More

Vasa 2018 Oct 16:1-11. Epub 2018 Oct 16.

4 Practice for Internal Medicine and Vascular Diseases, Vein Competence Centre, Halle, Germany.

Hypothenar or thenar hammer syndrome (HHS) and hand-arm vibration syndrome (HAVS) are diseases caused by acute or chronic trauma to the upper extremities. Since both diseases are generally related to occupation and are recognised as occupational diseases in most countries, vascular physicians need to be able to distinguish between the two entities and differentiate them from other diagnoses. A total of 867 articles were identified as part of an Internet search on PubMed and in non-listed occupational journals. Read More

Encephale 2018 Oct 9. Epub 2018 Oct 9.

Exercise and Sport Physiology and Medicine Unit, University of Douala, PO Box 7064 Logbessou, Bassa, Douala, Cameroon. Electronic address:

Objectives: This study aimed to evaluate the epidemiology of burnout syndrome among university teaching staff in Cameroon; and to establish if the practice of physical activities and leisures could have preventive effect.

Methods: A cross-sectional study using a self-administered questionnaire on socio-demographic characteristics, socio-professional conditions, Maslach Burnout Inventory-Educator Survey (MBI-ES) to evaluate burnout syndrome, and Ricci-Gagnon metrics to assess level of physical activities practice among grades of teaching staff, in the various faculties of the University of Douala, Cameroon.

Results: Three hundreds and three teaching staff members aged 43±7 years were included (69% males). Read More

Int J Environ Res Public Health 2018 10 5;15(10). Epub 2018 Oct 5.

Department of Healthcare Information and Management, Ming Chuan University, No. 5, Teh-Ming Rd., Gwei-Shan, Taoyuan 333, Taiwan.

The objective of the study was to explore the dynamic effects of socioeconomic status (SES) and lifestyle behaviors on the risks of metabolic syndrome (MS) or cardiovascular disease (CVD) in life course. The data of 12,825 subjects (6616 males and 6209 females) who underwent repeated examinations and answered repeated questionnaires from 2006 to 2014 at the Major Health Screening Center in Taiwan, was collected and analyzed. The trajectory of trends in the subjects' SES and lifestyle mobility over time was observed, and the effects of factors with potential impacts on health were tested and analyzed using multiple logistic regression and a generalized estimated equation model. Read More

Contemp Clin Dent 2018 Sep;9(Suppl 2):S256-S260

Department Oral Pathology, Faculty of Dentistry, Birjand University of Medical Sciences, Birjand, Iran.

Background And Aim: Burning mouth syndrome (BMS) may be defined as a burning sensation in the oral mucosa usually unaccompanied by clinical signs. Multiple conditions have been attributed to a burning sensation. The aim of this study was to determine the role of age and sex in BMS. Read More

Sleep Med 2018 Dec 22;52:51-57. Epub 2018 Aug 22.

Department of Epidemiology and Biostatistics, Amsterdam University Medical Centres, The Netherlands; Amsterdam Public Health Research Institute, The Netherlands. Electronic address:

Background: Previous studies have investigated the association between sleep duration, insomnia, day-time napping and metabolic syndrome individually, but never conjointly. In addition, the association with sleep medication use has yet to be investigated. We aimed to examine the associations between these sleep-related characteristics and the metabolic syndrome, individually and conjointly, in a population-based cohort. Read More

Immunol Cell Biol 2018 Sep 28. Epub 2018 Sep 28.

Seattle Children's Research Institute, Seattle, Washington, USA.

Hyper IgE syndromes comprise a group of rare primary immunodeficiency disorders characterized by a triad of atopic dermatitis, recurrent skin and lung infections along with elevated IgE levels. Job syndrome or autosomal dominant hyper IgE syndrome because of heterozygous loss-of-function mutations with dominant negative effect in signal transducer and activator of transcription-3 is the prototype of these disorders. However, several other genetically characterized immunodeficiency disorders have been identified over the past decade and joined the umbrella of hyper IgE syndromes including autosomal recessive mutations in the DOCK8, ZNF431 and PGM3 genes and heterozygous mutations with dominant negative effect in the CARD11 gene. Read More

J Occup Health 2018 Nov 27;60(6):485-493. Epub 2018 Sep 27.

Department of Epidemiology and Prevention, Center for Clinical Sciences, National Center for Global Health and Medicine.

Objective: To investigate associations of work-related stressors and their changes over time with the risk of developing metabolic syndrome (MetS) among Japanese manufacturing workers.

Methods: Participants were 1,040 employees aged 19 to 68 years who were free from MetS at baseline and completed the three year-interval follow-up survey. MetS was defined according to the Joint Interim Statement. Read More

Int J Environ Res Public Health 2018 09 25;15(10). Epub 2018 Sep 25.

Faculty of Health Sciences, University of Granada, Avenida de la Ilustración N. 60, 18016 Granada, Spain.

The correlation between the burnout syndrome and sociodemographic variables in nursing professionals has been widely studied though research results are contradictory. The aim of this study was to assess the impact of gender, marital status, and children on the dimensions of the burnout syndrome (emotional exhaustion, depersonalization, and personal accomplishment) in nursing professionals, as measured with the Maslach Burnout Inventory. The search was performed in May 2018 in the next databases: CINAHL, CUIDEN, Dialnet, Psicodoc, ProQuest Platform, OVID Platform, and Scopus with the search equation ("Maslach Burnout Inventory" OR "MBI") AND "nurs*", without using any search restriction. Read More

Am J Ind Med 2018 Nov 26;61(11):911-918. Epub 2018 Sep 26.

Research Group on Epidemiology on Chronic and Occupational Diseases (GERMINAL), Faculty of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.

Background: Shift work and psychosocial stressors may contribute to higher metabolic syndrome (MetS) incidence. Few studies investigated whether the presence of both factors simultaneously has a synergic effect on risk of MetS.

Methods: This cross-sectional analysis used baseline data (2008-2010) for 10 960 current workers from ELSA-Brasil. Read More

Soins Psychiatr 2018 Sep - Oct;39(318):12-19

CMME, service du professeur Philip Gorwood, hôpital Sainte-Anne, 1, rue Cabanis, 75014 Paris, France. Electronic address:

Although burnout syndrome was first described clinically about sixty years ago, it hasn't yet found its place in the classification of mental disorders. The wide range of clinical signs and aetiopathogenic theories has certainly contributed to this situation. There are different clinical forms of burnout and various therapeutic strategies. Read More

Rev Esp Sanid Penit 2018 May-Aug;20(2):40-46

Departamento de Trabajo Social y Servicios Sociales. Universidad de Murcia. Murcia (España).

Introduction: The specialized literature has revealed the high prevalence of burnout syndrome in the workforce of different prisons worldwide, as well as the influence of various risk factors associated with sociodemographic and occupational factors linked of the emergence of this occupational health problem. The current study measures the level of burnout and job satisfaction among the group of social workers Spanish prisons.

Methods: A cross-sectional analytical study was carried out on 59 social work professionals at the national level during 2017. Read More

Med Clin (Barc) 2018 Sep 13. Epub 2018 Sep 13.

Servicio de Medicina Interna, Hospital Santa Ana, Motril, Granada, España.

PLoS One 2018 12;13(9):e0203028. Epub 2018 Sep 12.

Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Purpose: This study aimed to explore the association between different obesity phenotypes and health-related quality of life (HRQoL) among Tehranian men and women.

Methods: The participants of this study were 2880 healthy adults (aged>19 years) who participated in Tehran Lipid and Glucose Study (TLGS). To obtain socio-demographic and HRQoL information, participants were interviewed by trained interviewers and were stratified by body mass index categories and metabolic status. Read More

Clin Infect Dis 2018 Sep 8. Epub 2018 Sep 8.

National Institute for Communicable Diseases, A division of the National Health Laboratory Service, South Africa.

Background: Congenital rubella syndrome (CRS) includes disorders associated with intrauterine rubella infection. Incidence of CRS is higher in countries with no rubella-containing vaccines (RCV) in their immunization schedules. In the World Health Organization African region, RCVs are being introduced as part of the 2012-2020 global measles and rubella strategic plan. Read More

Transfusion 2018 09 4;58(9):2122-2127. Epub 2018 Sep 4.

Center for Cancer and Blood Disorders, Phoenix Children's Hospital, Phoenix, Arizona.

Background: After hematopoietic stem cell transplantation (HSCT) autoimmune hemolytic anemia (AIHA) is a known and fairly common complication. It is often refractory to conventional therapies including corticosteroids, intravenous immunoglobulin, splenectomy, and the more recently described use of monoclonal antibodies. The high morbidity associated with these severe persistent cases elucidates the gaps in alternative therapies available for treatment. Read More

Clin Rev Allergy Immunol 2019 Feb;56(1):60-71

University of North Carolina School of Medicine, 321 S Columbia Street, Chapel Hill, NC, 27516, USA.

Occupational skin disease is common. It affects workers more often than reported. Contact dermatitis, both irritant and allergic, accounts for the majority of occupational skin diagnoses. Read More

PLoS One 2018 27;13(8):e0202977. Epub 2018 Aug 27.

Division of occupational medicine, Division of fanily medicine, Department of Family and Community Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China.

There was little information concerning the combined effect of occupational psychosocial hazards such as long working hours, high job stress, and high fatigue on the risk of cardiovascular and cerebrovascular diseases (CVD). The aim of this study was to investigate the interaction among occupational psychosocial hazards and the impact of metabolic syndrome (MetS) on the risk of CVD among bus drivers. The Taiwan Bus Driver Cohort Study involving 1014 professional drivers was established in 2005 and comprehensively studied. Read More

Int J Rheum Dis 2018 Aug;21(8):1514-1524

Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece.

Aims: Although rheumatic diseases constitute a leading cause of disability, the environmental risk factors for these diseases are not clarified. In the present study, we aim to systematically appraise the epidemiological credibility of the environmental risk factors for rheumatic diseases.

Methods: We systematically searched PubMed to capture meta-analyses of observational studies on environmental risk factors for the most prevalent rheumatic diseases. Read More

Int J Environ Res Public Health 2018 08 21;15(9). Epub 2018 Aug 21.

Department of Occupational and Environmental Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.

Workers may sometimes do the same work, but differ in their risk of health-related problems depending on whether the employment type is standard or non-standard. Furthermore, even with similar job and employment types, there may be differences in risk factors for health-related problems depending on sex. This study aimed to determine the prevalence of metabolic syndrome (MetS) by employment type and sex using data from the Fifth Korean National Health and Nutrition Examination Survey (KNHANES Ⅴ) (2010⁻2012) and KNHANES Ⅵ (2013⁻2015) conducted by the Korea Centers for Disease Control and Prevention. Read More

J Intellect Disabil Res 2018 Nov 19;62(11):941-951. Epub 2018 Aug 19.

Department of Psychology and Nisonger Center, UCEDD, The Ohio State University, Columbus, OH, USA.

Background: This study explored the role of demographic, psychosocial, stress and life event-related risk factors for psychopathology and challenging behaviour in a clinical sample of adults with Down syndrome.

Method: A convenience sample of adults with Down syndrome seen through a specialised clinic was assessed through interviews and questionnaires specifically designed for use in people with intellectual disabilities.

Results: Recent negative life events and stressors were significantly correlated with mental and behavioural health, and significantly predicted irritability, lethargy and depressed mood. Read More

Mamm Genome 2018 08 9;29(7-8):603-617. Epub 2018 Aug 9.

St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.

Spectacular progress has been made in the characterization of human hyper-IgE syndrome (HIES) over the last 50 years. HIES is a primary immunodeficiency defined as an association of atopy in a context of very high serum IgE levels, characteristic bacterial and fungal diseases, low-level clinical and biological inflammation, and various non-hematopoietic developmental manifestations. Somewhat arbitrarily, three disorders were successively put forward as the underlying cause of HIES: autosomal dominant (AD) STAT3 deficiency, the only disorder corresponding to the original definition of HIES, and autosomal recessive (AR) DOCK8 and PGM3 deficiencies, in which atopy and high serum IgE levels occur in a context of manifestations not seen in patients with typical HIES. Read More

Am J Hosp Palliat Care 2018 Aug 5:1049909118792517. Epub 2018 Aug 5.

1 Center for Research on End-Of-Life Care, Weill Cornell Medicine, NY, USA.

Background: Futile or potentially inappropriate care (futile/PIC) has been suggested as a factor contributing to clinician well-being; however, little is known about this association.

Objective: To determine whether futile/PIC provision is associated with measures of clinician well-being.

Design: Cross-sectional, self-administered, online questionnaire. Read More