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    2013 results match your criteria Job Syndrome

    1 OF 41

    Work productivity loss after mild traumatic brain injury.
    Arch Phys Med Rehabil 2017 Jul 28. Epub 2017 Jul 28.
    Department of Physical Medicine and Rehabilitation, Harvard Medical School; Spaulding Rehabilitation Hospital; & Home Base, A Red Sox Foundation and Massachusetts General Hospital Program, Boston, USA; 79/96 13th Street, Charlestown, MA, USA, 02129. Electronic address:
    Objective: To examine the completeness of return to work (RTW) and the degree of productivity loss in individuals who do achieve a complete RTW after mild traumatic brain injury (MTBI).

    Design: Multi-site prospective cohort.

    Setting: Outpatient concussion clinics. Read More

    Sedentary Occupation Workers Who Meet the Physical Activity Recommendations Have a Reduced Risk for Metabolic Syndrome: A Cross-Sectional Study.
    J Occup Environ Med 2017 Jul 24. Epub 2017 Jul 24.
    Graduate Program in Health Sciences, Federal University of Rio Grande do Norte, Natal, Brazil (Mr Browne, Mr Farias-Junior, Dr Costa); Department of Physical Education, Federal University of Rio Grande do Norte, Natal, Brazil (Mr Browne, Mr Farias-Junior, Mr Freire, Mr Schwade, Mr Macêdo, Drs Dantas, Costa); Naval Hospital of Natal, Natal, Natal, Brazil (Ms Montenegro); and Research Laboratory of Exercise Science, CEFAN, Brazilian Navy, Rio de Janeiro, Brazil (Mr Lopes).
    Objective: We tested the hypothesis that sedentary occupation workers who meet the physical activity recommendations present a lower risk for metabolic syndrome (MetS) than their nonactive counterparts.

    Methods: A cross-sectional study involving 502 sedentary occupation workers. Physical activity level was self-reported. Read More

    [Factors associated with job satisfaction of human resources in healthcare].
    Wiad Lek 2017;70(3 pt 1):443-448
    Introduction: Healthcare employee satisfaction is an important criterion for the efficiency of human resource management and prognostic impact factor for high turnover of staff. Furthermore, job satisfaction positively affects patient satisfaction, which is an important indicator for quality of care.

    Aim: The goal of our study was to identify factors associated with job satisfaction in healthcare organizations in Ukraine. Read More

    [Systemic sclerosis and occupational difficulties: Results of a prospective study].
    Rev Med Interne 2017 Jul 10. Epub 2017 Jul 10.
    Service de pathologies professionnelles et maintien en emploi, CHRU de Lille, Lille, France; Laboratoire de recherche, EA4487 axe droit/santé-travail, Lille, France. Electronic address:
    Between 9000 and 14000 people have systemic sclerosis (ScS) in France. The work is often affected. Our study aims to assess the frequency of professional difficulties (DP) of scleroderma patients, identify these DP, the symptoms involved and the solutions used. Read More

    [Burnout syndrome among generalist medical doctors of Douala region (Cameroon): Can physical activities be a protective factor?]
    Rev Med Brux 2017 ;38(1):10-15
    Département des Sciences biologiques, ENS, Université de Yaoundé I, Cameroun.
    Background: This study aimed to evaluate and document the importance of Burnout syndrome among generalist medical doctors (GMD) since no investigation have been carried in Cameroon.

    Methods: Cross-sectional study including 85 GMD using a self-administered questionnaire on socio-demographic characteristics, socioprofessional conditions, Maslach Burnout Inventory - Human Services Survey (MBI-HSS) to evaluate burnout, and Ricci-Gagnon physical activities level metrics.

    Results: 77 GMD (90. Read More

    Occupational contact allergy to omeprazole and ranitidine.
    Med Pr 2017 May 20;68(3):433-435. Epub 2017 Mar 20.
    University of Barcelona, Barcelona, Spain (Unit of Occupational Medicine, School of Medicine).
    Omeprazole is a proton pump inhibition and ranitidine is an H2 histamine receptor antagonist widely used in the treatment of gastroesophageal reflex disease, peptic ulcer disease, Zollinger-Ellison syndrome and as a protector of the gastric mucosae. We report a case of occupational contact allergy to omeprazole and ranitidine. A 48-year-old man, with no pre-existing history of atopy or lifestyle factors. Read More

    Burnout among healthcare workers at L'Aquila: its prevalence and associated factors.
    Psychol Health Med 2017 May 15:1-9. Epub 2017 May 15.
    c Department of Mental Health - Residences for Execution of Security Measures , ASL , Rome 5, Subiaco , Italy.
    Burnout, which is now recognized as a real problem in terms of its negative outcome on healthcare efficiency, is a stress condition that can be increased by exposure to natural disasters, such as the 2009 L'Aquila earthquake. This study aims to evaluate burnout syndrome, its associated risk factors and stress levels, and the individual coping strategies among healthcare professionals at L'Aquila General Hospital. A cross-sectional study of 190 healthcare workers was conducted. Read More

    Surgery for subacromial impingement syndrome in relation to occupational exposures, lifestyle factors and diabetes mellitus: a nationwide nested case-control study.
    Occup Environ Med 2017 May 10. Epub 2017 May 10.
    Danish Ramazzini Centre, Department of Occupational Medicine, Regional Hospital West Jutland-University Research Clinic, Herning, Denmark.
    Objectives: To estimate the risk of surgery for subacromial impingement syndrome (SIS) in relation to occupational exposures, lifestyle factors and diabetes mellitus.

    Methods: We conducted a case-control study nested in a register-based cohort study of the Danish working population. For each of 3000 first-time cases of surgery for SIS, two age-matched and sex-matched controls were drawn. Read More

    Perception and Attitude of Emergency Room Resident Physicians toward Middle East Respiratory Syndrome Outbreak.
    Emerg Med Int 2017 10;2017:6978256. Epub 2017 Apr 10.
    Department of Otolaryngology-Head and Neck Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
    Introduction. Middle East respiratory syndrome (MERS) outbreaks have had a considerable negative impact on health systems in Saudi Arabia. We aimed to study the psychological impact of a Middle East respiratory syndrome coronavirus (MERS-CoV) outbreak on emergency room resident physicians (ERRPs). Read More

    Risk assessment of manual handling operations at work with the key indicator method (KIM-MHO) - determination of criterion validity regarding the prevalence of musculoskeletal symptoms and clinical conditions within a cross-sectional study.
    BMC Musculoskelet Disord 2017 May 10;18(1):184. Epub 2017 May 10.
    Federal Institute for Occupational Safety and Health (BAuA), Nöldnerstrasse 40-42, D-10317, Berlin, Germany.
    Background: Manual handling operations (MHO) are known to be risk factors for work-related upper limb disorders (WRULDs), e.g. symptoms and conditions such as carpal tunnel syndrome. Read More

    Factors Affecting Resilience and Development of Posttraumatic Stress Disorder in Critical Care Nurses.
    Am J Crit Care 2017 May;26(3):184-192
    Meredith Mealer is an assistant professor, Department of Physical Medicine and Rehabilitation, Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado, and Rocky Mountain Mental Illness, Research, Education, and Clinical Center (MIRECC), Denver VA Health, Denver, Colorado. Jacqueline Jones is an associate professor, and Paula Meek is a professor, College of Nursing, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
    Background: Job stress and cumulative exposure to traumatic events experienced by critical care nurses can lead to psychological distress and the development of burnout syndrome and posttraumatic stress disorder. Resilience can mitigate symptoms associated with these conditions.

    Objective: To identify factors that affect resilience and to determine if the factors have direct or indirect effects on resilience in development of posttraumatic stress disorder. Read More

    Prognostic Variables for Patient Return-to-Work Interval Following Carpal Tunnel Release in a Workers' Compensation Population.
    Hand (N Y) 2017 May 28;12(3):246-251. Epub 2016 Jul 28.
    2 The Philadelphia Hand Center, PA, USA.
    Background: We hypothesize that depressive and anxiety disorders, chronic pain conditions, and work-related factors are significant determinants of the time interval for return to work (RTW) in the workers' compensation (WC) population following carpal tunnel release (CTR) surgery.

    Methods: We retrospectively reviewed records of all WC patients who underwent open CTR surgery over a 5-year period by 1 of 3 fellowship-trained hand surgeons. One hundred fifty-two wrists in 108 patients (64 unilateral, 44 bilateral) met the inclusion criteria. Read More

    Burnout in Dermatology Residents: a Canadian Perspective.
    Br J Dermatol 2017 Apr 4. Epub 2017 Apr 4.
    Division of Dermatology, University of Calgary, Calgary, Canada.
    Burnout is a syndrome comprised of emotional exhaustion (EE), depersonalization (DP), and reduced personal accomplishment (PA). It is associated with poor outcomes involving job performance and health.(1) Previous studies have reported burnout rates ranging from 18-84% during post-graduate medical education (i. Read More

    Emotional Wellness of Current Musculoskeletal Radiology Fellows.
    Acad Radiol 2017 Jun 21;24(6):682-693. Epub 2017 Mar 21.
    Department of Radiology, University of Washington, 1959 NE Pacific St, Seattle, WA 98195.
    Rationale And Objectives: Burnout is a psychological syndrome composed of emotional exhaustion, depersonalization, and sense of lack of personal accomplishment, as a result of prolonged occupational stress. The purpose of our study was to determine the prevalence of burnout among current musculoskeletal radiology fellows and to explore causes of emotional stress.

    Materials And Methods: A 24-item survey was constructed on SurveyMonkey using the Maslach Burnout Inventory. Read More

    HIV Education and Welfare Services in Primary Care: An Empirical Model of Integration in Brazil's Unified Health System.
    Int J Environ Res Public Health 2017 Mar 14;14(3). Epub 2017 Mar 14.
    Department of Biostatistics, Columbia University, 722 West 168th St. New York, NY 10032, USA.
    Integration of health education and welfare services in primary care systems is a key strategy to solve the multiple determinants of chronic diseases, such as Human Immunodeficiency Virus Infection and Acquired Immune Deficiency Syndrome (HIV/AIDS). However, there is a scarcity of conceptual models from which to build integration strategies. We provide a model based on cross-sectional data from 168 Community Health Agents, 62 nurses, and 32 physicians in two municipalities in Brazil's Unified Health System (UHS). Read More

    Medically unexplained physical symptoms (MUPS) among adults in Canada: Comorbidity, health care use and employment.
    Health Rep 2017 Mar;28(3):3-8
    Health Analysis Division, Statistics Canada, Ottawa, Ontario.
    Based on data from the 2014 Canadian Community Health Survey and the 2012 Canadian Community Health Survey-Mental Health, this study provides estimates of the prevalence of medically unexplained physical symptoms (MUPS) in the household population aged 25 or older. MUPS are examined in relation to sociodemographic characteristics, physical and mental comorbidity, health care use and unmet needs, labour force participation and productivity. In 2014, 5. Read More

    Pediatric anaphylaxis and hyper IgE syndrome.
    J Asthma Allergy 2017 28;10:31-33. Epub 2017 Feb 28.
    Department of Pediatrics, Rady Childrens Hospital, San Diego, CA, USA.
    Patients with autosomal-dominant (AD) hyper immunoglobulin E (IgE) syndrome (HIES) or Job syndrome develop frequent dermatologic and pulmonary infections. As patients have an extreme elevation of IgE levels, this database analysis study sought to study the association between AD HIES, Job syndrome, and anaphylaxis. HIES is a heterogeneous group of immune disorders characterized by extremely elevated levels of serum IgE. Read More

    [Features of peripheral nerve injuries in workers exposed to vibration: an analysis of 197 cases].
    Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2016 Dec;34(12):931-934
    Department of Occupational Diseases, Shenzhen Prevention and Treatment Center for Occupational Dieases, Shenzhen 518000, China.
    Objective: To investigate the features of peripheral nerve injuries in workers exposed to vibration. Methods: A total of 197 male workers [median age: 34 years (21-50 years) ; median working years of vibration exposure: 7.3 years (1-20 years) ] engaged in grinding in an enterprise were enrolled. Read More

    The predictors of quality of life in women with polycystic ovarian syndrome.
    Int J Nurs Pract 2017 Jun 21;23(3). Epub 2017 Feb 21.
    Reproductive Health Research Center, Urmia University of Medical Sciences, Urmia, Iran.
    Polycystic ovarian syndrome (PCOS) is one of the most common endocrine disorder that may be effective in reducing the quality of life. This study aimed to determine the predictors of quality of life in women with PCOS. This cross-sectional study was conducted on 174 women with PCOS who attended in public and private fertility clinics in Urmia (West Azerbaijan, Iran), 2015. Read More

    Relationship of work-family conflict, self-reported social support and job satisfaction to burnout syndrome among medical workers in southwest China: A cross-sectional study.
    PLoS One 2017 16;12(2):e0171679. Epub 2017 Feb 16.
    Center for Health Information of Sichuan Province, Chengdu, Sichuan Province, China.
    Background: Burnout is a psychosomatic syndrome widely observed in Chinese medical workers due to the increasing cost of medical treatment, excessive workload, and excessive prescribing behavior. No studies have evaluated the interrelationship among occupational burnout, work-family conflict, social support, and job satisfaction in medical workers. The aim of this study was to evaluate these relationships among medical workers in southwest China. Read More

    Effects of work environment on patient and nurse outcomes.
    Br J Nurs 2017 Feb;26(3):172-176
    Professor, Faculty of Nursing, School of Health Sciences, National and Kapodistrian University of Athens, Greece.
    Background: Several parameters of the nurse's work environment lead to fewer patient complications and lower nurse burnout. The aim of this systematic review was the analysis of research data related to the effect of nurses' work environments on outcomes for both patients and nurses.

    Methods: Medline was searched by using keywords: 'working conditions', 'work environment', 'nurses', 'nursing staff', 'patients', 'outcomes'. Read More

    Prevalence of Burnout Syndrome and Associated Factors Among Rural Health Workers (Behvarzes) in South Khorasan.
    Iran Red Crescent Med J 2016 Oct 9;18(10):e25390. Epub 2016 Jul 9.
    Health Center, Birjand University of Medical Sciences, Birjand, IR Iran.
    Background: Essential primary health care is delivered through the public health center PHC network by public health workers (Behvarzs). Health workers are exposed to different types of stresses while working.

    Objectives: The aim of this study is to determine the prevalence of burnout and associated factors among rural health workers in the health centers of Birjand University of Medical Sciences. Read More

    Prevalence of burnout among musculoskeletal radiologists.
    Skeletal Radiol 2017 Apr 2;46(4):497-506. Epub 2017 Feb 2.
    Department of Radiology, University of Washington, 4245 Roosevelt Way NE, Seattle, WA, 98105, USA.
    Objective: Burnout is a job-related psychological syndrome with three aspects: emotional exhaustion, depersonalization, and perceived lack of personal accomplishment. Burnout is associated with deleterious effects on both workers and their work. When burnout affects physicians, their well-being, longevity, and care of patients are at risk. Read More

    Time spent in sedentary posture is associated with waist circumference and cardiovascular risk.
    Int J Obes (Lond) 2017 May 31;41(5):689-696. Epub 2017 Jan 31.
    School of Medicine, Life-Course Nutrition and Health, University of Glasgow, Glasgow, UK.
    Background: The relationship between metabolic risk and time spent sitting, standing and stepping has not been well established. The present study aimed to determine associations of objectively measured time spent siting, standing and stepping, with coronary heart disease (CHD) risk.

    Methods: A cross-sectional study of healthy non-smoking Glasgow postal workers, n=111 (55 office workers, 5 women, and 56 walking/delivery workers, 10 women), who wore activPAL physical activity monitors for 7 days. Read More

    Association between insomnia symptoms, job strain and burnout syndrome: a cross-sectional survey of 1300 financial workers.
    BMJ Open 2017 Jan 13;7(1):e012816. Epub 2017 Jan 13.
    Université Paris Descartes, Hôtel Dieu, EA 7330 VIFASOM (Vigilance Fatigue et Sommeil), Paris, France.
    Objectives: Professional burnout is closely related to work stress but less frequently associated with disturbed sleep. This study determines whether job strain and sleep disturbances are associated risk factors of burnout among financial workers.

    Design: Observational study. Read More

    Stigma and its correlates in patients with schizophrenia attending a general hospital psychiatric unit.
    Indian J Psychiatry 2016 Jul-Sep;58(3):291-300
    Department of Psychiatry, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
    Background: Very few studies from India have studied stigma experienced by patients with schizophrenia.

    Aim Of The Study: To study stigma in patients with schizophrenia (in the form of internalized stigma, perceived stigma and social-participation-restriction stigma) and its relationship with specified demographic and clinical variables (demographic variables, clinical profile, level of psychopathology, knowledge about illness, and insight).

    Materials And Methods: Selected by purposive random sampling, 100 patients with schizophrenia in remission were evaluated on internalized stigma of mental illness scale (ISMIS), explanatory model interview catalog stigma scale, participation scale (P-scale), positive and negative syndrome scale for schizophrenia, global assessment of functioning scale, scale to assess unawareness of mental disorder, and knowledge of mental illness scale. Read More

    Lessons from a seven-year experience of paediatric HIV in Pakistan: A single centre experience.
    J Pak Med Assoc 2017 Jan;67(1):105-110
    Department of Pediatrics, Shifa International Hospital, Islamabad.
    Objective: To describe demographic, clinical and immunologic features of children with human immunodeficiency virus.

    Methods: This descriptive study was conducted at the Shifa International Hospital, Islamabad, Pakistan, from 2005 to 2011, and comprised children with human immunodeficiency virus and acquired immune deficiency syndrome. Patients with detailed physical examination and appropriate investigations and those eligible for therapy were included. Read More

    Factors Influencing Emergency Nurses' Burnout During an Outbreak of Middle East Respiratory Syndrome Coronavirus in Korea.
    Asian Nurs Res (Korean Soc Nurs Sci) 2016 Dec 9;10(4):295-299. Epub 2016 Nov 9.
    College of Nursing, Gachon University, Incheon, South Korea. Electronic address:
    Purpose: Emergency department (ED) nurses suffer from persistent stress after experiencing the traumatic event of exposure to Middle East respiratory syndrome coronavirus (MERS-CoV), which can subsequently lead to burnout. This study aimed to assess ED nurses' burnout level during an outbreak of MERS-CoV and to identify influencing factors in order to provide basic information for lowering and preventing the level of burnout.

    Methods: Study participants were ED nurses working in eight hospitals designated for treating MERS-CoV-infected patients in Korea. Read More

    Diagnostic accuracy of salivary and serum-free light chain assays in primary Sjögren's syndrome: a pilot study.
    Int J Rheum Dis 2017 Jun 30;20(6):760-766. Epub 2016 Dec 30.
    Department of Clinical Immunology & Rheumatology, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.
    Objective: To estimate levels of salivary and serum free light chains (FLCs) and explore its utility as a biomarker in primary Sjögren's syndrome (pSS).

    Methods: Patients with pSS classified by American European Consensus group 2002 or American College of Rheumatology 2012 criteria between January 2015 and August 2015 were included. Healthy staff and non-first degree relatives of patients constituted controls. Read More

    Complex regional pain syndrome: medical and legal ramifications of clinical variability and experience and perspective of a practicing clinician.
    J Pain Res 2017 19;10:9-14. Epub 2016 Dec 19.
    Department of Neurology, Albany Medical College, Albany, NY, USA.
    Objective: The aim of this study was to demonstrate the ramifications of clinical variability of complex regional pain syndrome (CRPS) and how they can affect the various aspects of this condition, favorably or unfavorably, for both patients and participating medical and legal professionals.

    Methods: Twelve patients diagnosed with CRPS at different times in the past 25 years were followed up, and their signs and symptoms were reviewed for variability. None had preexisting or ongoing medical disorders and prior injury to the peripheral nerves or musculoskeletal tissues. Read More

    Prevalence of Myofascial Pain Syndrome in Chronic Non-Specific Neck Pain: A Population-Based Cross-Sectional Descriptive Study.
    Pain Med 2016 Dec 20;17(12):2369-2377. Epub 2016 Jun 20.
    Physiotherapy in Women's Health Research Group, Department of Physiotherapy University of Alcalá, Alcalá de Henares, Madrid, Spain.
    Background: Chronic non-specific neck pain is a frequent complaint. It is a recognized medical and socioeconomic problem and a frequent cause of job absenteeism. In recent years, case reports about myofascial pain syndrome (MPS) are emerging among patients suffering from pain. Read More

    The Surgical Repair of a Hyperimmunoglobulin E Syndrome Associated Ascending Aortic Aneurysm.
    Ann Thorac Surg 2017 Jan;103(1):e65-e67
    Department of Pediatric Cardiology, Inonu University Faculty of Medicine, Malatya, Turkey.
    Hyperimmunoglobulin E syndrome (HIES) is an immunodeficiency disorder that manifests itself by affecting more than one system. Arterial aneurysms are among the significant complications associated with HIES. Surgical procedures for patients with such aneurysms are uncommon. Read More

    Burnout syndrome and job satisfaction in Greek residents: exploring differences between trainees inside and outside the country.
    Ann Transl Med 2016 Nov;4(22):444
    Thoracic Surgery Department, Theagenio Cancer Hospital, Thessaloniki, Greece.
    Background: The purpose of this study is to investigate the levels of burnout among Greek residents, highlighting potential differences between those practicing at home and abroad, as well as to investigate correlations with demographic, individual and labor factors.

    Methods: The research was conducted on a sample of 131 residents, using an anonymous questionnaire which included demographic, individual and labor characteristics, Maslach's Burnout Inventory, questions regarding job and life satisfaction levels, working conditions and the impacts of the economic recession.

    Results: Fifty two point seven percent of the sample were training in the Greek National Health Service (N. Read More

    Shiftwork Is Not Associated with Increased Risk of NAFLD: Findings from the National Health and Nutrition Examination Survey.
    Dig Dis Sci 2017 Feb 19;62(2):526-533. Epub 2016 Dec 19.
    Section of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA.
    Aims: There is increased focus on the metabolic impact of shiftwork, especially given the significant number of employees who work nighttime or rotating shifts. Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic syndrome. We conducted a cross-sectional study to examine the association between shiftwork and the risk of NAFLD. Read More

    The determination of the levels of burnout syndrome, organizational commitment, and job satisfaction of the health workers.
    Niger J Clin Pract 2017 Jan;20(1):48-56
    Department of Biometry and Genetic, Faculty of Agriculture, Ahi Evran University, Kirsehir, Turkey.
    Context: The concept of burnout is an important element for efficiency in occupational groups such as health and education, which necessitate constant communication with people and have a busy schedule.

    Aims: The determination of the levels of burnout syndrome, organizational commitment, and job satisfaction of the health workers.

    Materials And Methods: A questionnaire consisting of four parts was prepared so as to measure the levels of organizational commitment, job satisfaction, and burnout of the medical staff of the institution. Read More

    The impact of epidemics on labor market: identifying victims of the Middle East Respiratory Syndrome in the Korean labor market.
    Int J Equity Health 2016 Dec 1;15(1):196. Epub 2016 Dec 1.
    Department of Economics, Sungkyunkwan University, 25-2 Sungkyunkwan-ro, Jongno-gu, Seoul, 110-745, Republic of South Korea.
    Background: The vulnerability approach suggests that disasters such as epidemics have different effects according not only to physical vulnerability but also to economic class (status). This paper examines the effect of the Middle East Respiratory Syndrome epidemic on the labor market to investigate whether vulnerable groups become more vulnerable due to an interaction between the socio-economic structure and physical risk.

    Methods: This paper examines the effect of the Middle East Respiratory Syndrome epidemic on the labor market by considering unemployment status, job status, working hours, reason for unemployment and underemployment status. Read More

    Novel mutation in DOCK8-HIES with severe phenotype and successful transplantation.
    Clin Immunol 2017 May 23;178:39-44. Epub 2016 Nov 23.
    King Faisal Specialist Hospital and Research Center, Department of Medicine, Allergy and Immunology section, P.O Box 3354, Riyadh 11211, MBC 46, Saudi Arabia; Alfaisal University, Saudi Arabia. Electronic address:
    Background: Hyper-IgE syndrome (HIES) due to DOCK8 deficiency is an autosomal recessive (AR) primary combined immunodeficiency which results in significant morbidity and mortality at a young age. Different mutations in the DOCK8 gene can lead to variable severity of the disease.

    Objective: We evaluated the genetic mutations in three related patients with severe clinical manifestations suggestive of AR HIES. Read More

    Executive Leadership and Physician Well-being: Nine Organizational Strategies to Promote Engagement and Reduce Burnout.
    Mayo Clin Proc 2017 Jan 18;92(1):129-146. Epub 2016 Nov 18.
    President and Chief Executive Officer, Mayo Clinic, Rochester, MN.
    These are challenging times for health care executives. The health care field is experiencing unprecedented changes that threaten the survival of many health care organizations. To successfully navigate these challenges, health care executives need committed and productive physicians working in collaboration with organization leaders. Read More

    Sexually Transmitted Infections Among Hospitalized Patients With Human Immunodeficiency Virus Infection and Acquired Immune Deficiency Syndrome (HIV/AIDS) in Zahedan, Southeastern Iran.
    Int J High Risk Behav Addict 2016 Sep 2;5(3):e28028. Epub 2016 Jul 2.
    Infectious Diseases and Tropical Medicine Research Center, Zahedan University of Medical Sciences, Zahedan, IR Iran.
    Background: Studies show that nearly 40 million people are living with human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS) around the world and since the beginning of the epidemic, about 35 million have died from AIDS. Heterosexual intercourse is the most common route for transmission of HIV infection (85%). People with a sexually transmitted infection (STI), such as syphilis, genital herpes, chancroid, or bacterial vaginosis, are more likely to obtain HIV infection during sex. Read More

    Tyrosine kinase 2 is not limiting human antiviral type III interferon responses.
    Eur J Immunol 2016 Nov 5;46(11):2639-2649. Epub 2016 Oct 5.
    Center for Chronic Immunodeficiency, Faculty of Medicine, Medical Center-University of Freiburg, Freiburg, Germany.
    Tyrosine kinase 2 (TYK2) associates with interferon (IFN) alpha receptor, IL-10 receptor (IL-10R) beta and other cytokine receptor subunits for signal transduction, in response to various cytokines, including type-I and type-III IFNs, IL-6, IL-10, IL-12 and IL-23. Data on TYK2 dependence on cytokine responses and in vivo consequences of TYK2 deficiency are inconsistent. We investigated a TYK2 deficient patient, presenting with eczema, skin abscesses, respiratory infections and IgE levels >1000 U/mL, without viral or mycobacterial infections and a corresponding cellular model to analyze the role of TYK2 in type-III IFN mediated responses and NK-cell function. Read More

    [Socio professional impact of surgical release of carpal tunnel syndrome].
    Pan Afr Med J 2016 13;24:234. Epub 2016 Jul 13.
    Département de Médecine de Travail et d'Ergonomie-Faculté de Médecine de Monastir, Tunisie.
    The objective was studying the socio-professional impact of release surgery for carpal tunnel syndrom (CTS). We conducted a cross-sectional study of patients operated for work-related CTS; data were collected in the Occupational Health Department at the University Hospital Tahar Sfar in Mahdia, Tunisia over a period of 8 years, from 1 January 2006 to December 2013. Data collection was performed using a survey form focusing on participants' socio-professional and medical characteristics and on their professional future. Read More

    Protein stabilization improves STAT3 function in autosomal dominant hyper-IgE syndrome.
    Blood 2016 Dec 31;128(26):3061-3072. Epub 2016 Oct 31.
    Division of Internal Medicine, University of Texas MD Anderson Cancer Center, Houston, TX; and.
    Autosomal dominant hyper-IgE syndrome (AD-HIES) is caused by dominant-negative mutations in STAT3; however, the molecular basis for mutant STAT3 allele dysfunction is unclear and treatment remains supportive. We hypothesized that AD-HIES mutations decrease STAT3 protein stability and that mutant STAT3 activity can be improved by agents that increase chaperone protein activity. We used computer modeling to characterize the effect of STAT3 mutations on protein stability. Read More

    Born and bred to burn out: A life-course view and reflections on job burnout.
    J Occup Health Psychol 2017 Jul 10;22(3):354-364. Epub 2016 Oct 10.
    Center of Excellence for Positive Organizational Psychology, Erasmus University Rotterdam.
    Burnout is a response to prolonged stressors at work, and is defined as a chronic syndrome including exhaustion, cynicism, and reduced professional efficacy. The 40 years of research on burnout have yielded thousands of studies on its measurement, antecedents, correlates, and consequences. However, most of these studies have used a cross-sectional design, and only very few have addressed burnout from a life-course perspective. Read More

    Prognostic factors for return-to-work following surgery for carpal tunnel syndrome: a systematic review.
    JBI Database System Rev Implement Rep 2016 Sep;14(9):135-216
    1School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Australia 2Nursing Research Centre, Mater Health Services, Brisbane, Australia 3Brisbane Hand and Upper Limb Research Institute, Brisbane Private Hospital, Brisbane, Australia 4The Queensland Centre for Evidence Based Nursing and Midwifery: a Joanna Briggs Institute Centre of Excellence, Adelaide, Australia 5Orthopaedic Department, Princess Alexandra Hospital, Woolloongabba, Australia 6School of Medicine, The University of Queensland, Brisbane, Australia 7MOVE, VU University, Amsterdam, The Netherlands.
    Background: Carpal tunnel syndrome (CTS) is a common problem, that can be effectively managed by surgery. Screening for prognostic factors is important to identify workers who are at a greater risk of a poor work outcome in order to implement tailored interventions to facilitate their return-to-work.

    Objective: To synthesize the best available evidence on the association of preoperative prognostic factors with work-related outcomes in people who have undergone carpal tunnel surgery. Read More

    Job stress models for predicting burnout syndrome: a review.
    Ann Ist Super Sanita 2016 Jul-Sep;52(3):443-456
    Servizio Sanitario della Polizia di Stato, Ministero dell'Interno, Rome, Italy.
    In Europe, the Council Directive 89/391 for improvement of workers' safety and health has emphasized the importance of addressing all occupational risk factors, and hence also psychosocial and organizational risk factors. Nevertheless, the construct of "work-related stress" elaborated from EU-OSHA is not totally corresponding with the "psychosocial" risk, that is a broader category of risk, comprising various and different psychosocial risk factors. The term "burnout", without any binding definition, tries to integrate symptoms as well as cause of the burnout process. Read More

    Burnout syndrome in critical care team members: A monocentric cross sectional survey.
    Anaesth Crit Care Pain Med 2017 Aug 23;36(4):223-228. Epub 2016 Sep 23.
    Surgical Intensive Care Unit, Amiens University Hospital, 80000 Amiens, France; Cardiac, Thoracic and Vascular Intensive Care Unit, Amiens University Hospital, 80000 Amiens, France; Neurological Intensive Care Unit, Amiens University Hospital, 80000 Amiens, France; Inserm U1088, University of Picardy-Jules-Verne, 80000 Amiens, France. Electronic address:
    Introduction: There has been a growing interest in evaluating the occurrence of burnout syndrome (BOS) among intensive care units (ICU) team over recent years. The aims of this study were to determine the prevalence of BOS among staff working in the Amiens University Hospital and to assess associated factors.

    Patients And Methods: Prospective observational study based on self-administered questionnaires filled in by physicians and non-physicians working in 3 ICUs. Read More

    Anesthetic practices for patients with preeclampsia or HELLP syndrome: A survey.
    J Turk Ger Gynecol Assoc 2016 1;17(3):128-33. Epub 2016 Sep 1.
    Department of Obstetrics and Gynecology, The University of Mississippi Medical Center, Jackson, USA.
    Objective: Substantial controversy exists regarding anesthetic management for patients with preeclampsia or hemolysis, elevated liver enzymes, low platelet count (HELLP) syndrome. Experts, researchers, clinicians, and residents in Turkey were surveyed about their practices.

    Material And Methods: Questionnaires were distributed to attendees at a national conference, and they were filled out immediately. Read More

    [Gender aspects in female and male physicians : Occupational and psychosocial stress].
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2016 Oct;59(10):1343-50
    Klinik für Psychosomatische Medizin und Psychotherapie, Universitätsklinikum Ulm, Albert-Einstein-Allee 23, 89081, Ulm, Deutschland.
    Background: International studies have shown that physicians have an elevated risk of developing depression or burnout syndrome. Gender aspects with regard to occupation are discussed in German politics and society. Currently, there is little data comparing female and male physicians with regard to stress at work, depression, and burnout. Read More

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